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The Exploration Of Nanotoxicological Copper And Interspecific Saccharomyces Hybrids, Matthew Joseph Winans Phd

Graduate Theses, Dissertations, and Problem Reports (ETD)

Nanotechnology takes advantage of cellular biology’s natural nanoscale operations by interacting with biomolecules differently than soluble or bulk materials, often altering normal cellular processes such as metabolism or growth. To gain a better understanding of how copper nanoparticles hybridized on cellulose fibers called carboxymethyl cellulose (CMC) affected growth of Saccharomyces cerevisiae, the mechanisms of toxicity were explored. Multiple methodologies covering genetics, proteomics, metallomics, and metabolomics were used during this investigation. The work that lead to this dissertation discovered that these cellulosic copper nanoparticles had a unique toxicity compared to copper. Further investigation suggested a possible ionic or molecular mimicry …

Evolutionary Genomics Of Dynamic Sex Chromosomes In The Salicaceae, Ran Zhou

Graduate Theses, Dissertations, and Problem Reports (ETD)

Identifying the sex-determination region (SDR) and other genomic features of sex chromosomes are of great importance in the studies of the evolution of sex. However, the process of accurately identifying the size and location of the SDR is often difficult, even when a genomic sequence is available. This usually is hindered by large repetitive elements and a lack of recombination in the SDR. In this thesis, I assemble sex chromosomes with whole genomic sequencing data, identify SDRs and explore their genomic features in two sister species from the Salicaceae family. I also develop an interpretation of the lability of the …

An Interactive Mobile Equipment Task-Training With Virtual Reality, Lazar Zujovic

Graduate Theses, Dissertations, and Problem Reports (ETD)

Improving the quality of equipment training for the Heavy Equipment Operators (HEO) is a critical task in the ever-lasting effort to improve safety and eliminate equipment-related injuries in mining environments. Traditional miner training includes the use of hardcopy documents and video instructions. However, modern mobile and computer technology offers tremendous potential to improve the training process. One major responsibility for the heavy-machine operators is proper machine inspection. Establishing new training methods that utilize modern technologies—such as 360-degree images, videos, and Virtual Reality—and implementing computers for training purposes have a potential to help new operators learn how to conduct proper machine …

Mnemonic Discrimination And Social Anxiety: The Role Of State Anxiety, Gabriella T. Ponzini

Graduate Theses, Dissertations, and Problem Reports (ETD)

The Mnemonic Similarity Task (MST) measures mnemonic discrimination, or the ability to correctly identify new stimuli from highly similar, old stimuli. Neuroscientific and theoretical suppositions suggest that poor mnemonic discrimination may represent a potential risk or maintenance factor for anxious individuals. However, state affect appears to moderate the relation between mnemonic discrimination abilities and trait anxiety. The current study aimed to elucidate the nascent research on mnemonic discrimination and anxiety by evaluating the MST in a specific subtype of anxiety (i.e., social anxiety) and utilizing a clinically relevant stressor task (i.e., knowledge of a future speech). Participants (N = …

Role Of Ciliary Proteins Adp Ribosylation Factor Like Gtpase 13b (Arl13b) And Bardet-Biedl Syndrome-8 (Bbs8) In Photoreceptor Outer Segment Morphogenesis, Maintenance, And Viability, Tanya L. Dilan

Graduate Theses, Dissertations, and Problem Reports (ETD)

Photoreceptor neurons are modified primary cilia with an extended ciliary compartment known as the outer segment (OS). The mechanisms behind the elaboration of photoreceptor cilia, OS morphogenesis, and maintenance remain poorly understood. In this work, we focused on dissecting the role of two ciliary proteins, the small GTPase ADP-ribosylation factor-like GTPase 13B (ARL13B) and Bardet-Biedl Syndrome-8 (BBS8) in the context of photoreceptor biology. Both BBS8 and ARL13B are linked to defects in ciliogenesis (cilia development) and Retinitis Pigmentosa (vision loss). ARL13B is implicated in regulating ciliary length, and BBS8 is part of the Bardet-Biedl Syndrome complex (BBSome); the BBSome is …

Towards Large Eddy Simulation Of A Staged, Pressurized Oxy-Fuel Combustor, Alain Islas Montero

Graduate Theses, Dissertations, and Problem Reports (ETD)

Identified by the DoE among the novel and transformational technologies, staged-pressurized oxy-fuel combustion (SPOC) is a promising low-cost, low-emission, and highly efficient tool for carbon capture utilization and storage (CCUS), with pulverized coal burning under elevated pressures and low recycled flue gas. A lab-scale SPOC facility, under establishment at Washington University in St. Louis (WUSTL), causes the critical need to develop accurate and reliable computational models to assist the ongoing WUSTL experiments. This constitutes the driving motivation of the present work. Specifically, comprehensive three-dimensional Large-eddy simulations (LES) of the lab-scale SPOC reactor, with most of important characteristics of a multi-phase …

Comparative Study Of Model-Based And Learning-Based Disparity Map Fusion Methods, Douglas E. Kerr Jr.

Graduate Theses, Dissertations, and Problem Reports (ETD)

Creating an accurate depth map has several, valuable applications including augmented/virtual reality, autonomous navigation, indoor/outdoor mapping, object segmentation, and aerial topography. Current hardware solutions for precise 3D scanning are relatively expensive. To combat hardware costs, software alternatives based on stereoscopic images have previously been proposed. However, software solutions are less accurate than hardware solutions, such as laser scanning, and are subject to a variety of irregularities. Notably, disparity maps generated from stereo images typically fall short in cases of occlusion, near object boundaries, and on repetitive texture regions or texture-less regions. Several post-processing methods are examined in an effort to …

Development Of An Activity-Based Windowing Approach To Evaluate Real-World Nox Emissions From Modern Medium And Heavy-Duty Diesel Trucks, Rasik Pondicherry

Graduate Theses, Dissertations, and Problem Reports (ETD)

The introduction of in-use emissions regulations by the United States Environmental Protection Agency (U.S.EPA) requires medium-duty (MD) and heavy-duty (HD) engine manufacturers to demonstrate emissions compliance during in-fleet operation. In the United States (U.S.), the Not-to-Exceed (NTE) method is used to evaluate real-world emissions compliance from on-highway MD and HD trucks. Regulatory agencies, engine manufacturers and research entities have identified that the NTE method incorporates numerous exclusions and evaluates emissions compliance only under selective operating conditions that are favorable for the selective catalytic reduction (SCR) system to reduce oxides of nitrogen (NOx) emissions efficiently. Such operation is typically encountered only …

Alternative Media And Mulches In Organic Vegetable Production, Heather R. Griffith

Graduate Theses, Dissertations, and Problem Reports (ETD)

Reducing or eliminating waste from organic vegetable production can conserve money as well as resources. Conventional greenhouse production of vegetable transplants often relies on abundant fertigation which produces large amounts of polluted runoff, and the field production of organic vegetables frequently relies on the use of polyethylene mulch. A greenhouse study was conducted to determine if organic transplants can be successfully produced in a greenhouse under reduced soil moisture in order to reduce leaching of nutrients and potential water pollution. To test this, we compared the effect of reduced irrigation volumes to the standard practice of irrigating with 120% of …

Types And Causes Of Physiological Injury In Piano Playing, With Emphasis On Piano Pedagogy In China, Ruixi Niu

Graduate Theses, Dissertations, and Problem Reports (ETD)

Among musicians who seek medical help for their injuries each year, half are pianists. Improper playing technique is a factor influencing the development of injury. This research project focuses on the types and causes of physiological injury in the process of piano playing and includes methods of avoiding such injuries.

The types of piano-related physiological injury and associated conditions that are discussed include tenosynovitis, focal dystonia, and muscle pain. Relevant literature and investigative data—and some legends—are compared and sorted. Chinese pedagogical views concerning piano technique are discussed, along with ongoing debates concerning injury prevention and the appropriate use of exercises …

Evaluation Of The Impact Of An Educational Intervention Aimed At Improving Tuberculosis Infection Control Knowledge Among Health Care Workers In A Military Treatment Facility: A Quality Improvement Project, Allen C. Potter

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Florida (FL) is one of the top five states in the nation for Tuberculosis (TB) infections. A majority of new infections can be found in the minority populations which represents 78% of all TB infections in the state. A combination of TB rates in FL, Orlando located 60 miles away and a transient population who frequently deploys worldwide to austere locations may result in an increased risk of acquiring TB. Literature suggests Health Care Providers (HCPs) obtain training regarding TB Infection Control (TB-IC). The Patrick AFB Military Treatment Facility (MTF) lacked a TB Infection Control (TB-IC) plan. Objective: The …

Interoperability Of Ip-Based Cameras, Faythe C. Maston

Graduate Theses, Dissertations, and Problem Reports (ETD)

In this day and age of advancing technology and increasing crime, more and more citizens are investing in technology to increase their personal security. One such technology is the use of home-based IP security systems. These systems are comprised of one or more IP-based security cameras with owners preferring to have a way to view all camera feeds at once. Since not all security cameras are made to interact with each other, it is necessary to find a program that allows a user to view all security cameras at once, regardless of what brand of cameras they use. After researching, …

Perceptions Of Asian American Representation In Entertainment Media, Lydia Susan Owens

Graduate Theses, Dissertations, and Problem Reports (ETD)

The rise of Asian American representation in entertainment media has brought new questions to the current perceptions of Asian Americans in American culture. Where whitewashing of roles or stereotypes of the Model Minority were once portrayed frequently in the past, there are now more diverse stories being shown. When representational images are being shown in entertainment media, there is need for a media literacy lens to critically analyze these images. With this rise in Asian American representation, what are current perceptions of Asian Americans in American culture and American entertainment media? What are current levels of media literacy? This study …

Comparison Of Skeletal And Dentoalveolar Changes Between Two Bone-Borne Maxillary Expanders, Mohamad Sarraj

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction: Bone-borne maxillary expander (BBME) are designed to provide additional anchorage to widen the maxillary arch for patients who exhibit maxillary transverse deficiency. One form of BBME is the hybrid BBME which uses mini-implants (bone-borne) and posterior teeth (tooth-borne) as anchorage for maxillary expansion. The other form of BBME is absolute BBME which only uses mini-implants as anchorage. It is not clear in the literature if there is a difference in skeletal and dental changes with these two types of expanders. The objective of this study was to compare the skeletal, dentoalveolar, and periodontal changes between the hybrid and the …

Spatio-Temporal Analysis Of Crime Incidents For Forensic Investigation, Jamie Spencer Spaulding

Graduate Theses, Dissertations, and Problem Reports (ETD)

Crime analysis and mapping has been routinely employed to gather intelligence which informs security efforts and forensic investigations. Traditionally, geographic information systems in the form of third-party mapping applications are used for analysis of crime data but are often expensive and lack flexibility, transparency, or efficiency in uncovering associations and relationships in crime. Each crime incident and article of evidence within that incident has an associated spatial and temporal component which may yield significant and relevant information to the case. Wide variations exist in the techniques that departments use and commonly spatial and temporal components of crime are evaluated independently, …

Quality Improvement Of Substance Misuse Screening Of Older Adults In Primary Care Using Evidence-Based Training, Kelly Lopez

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background

The largest increase in preventable overdose deaths from 1999-2017 occurred among adults 50 and older, yet substance misuse among older adults is often not screened for or recognized in primary care settings. This oversight has been attributed to many factors, including age-related biases, unrecognized psychosocial and physiological differences, stigmatization, and a rapidly growing geriatric population.

Objectives

A quality improvement program using evidence-based educational training was implemented in a primary care setting with the intention to expand care knowledge and ultimately improve screening practices of older adults, especially those suffering from substance misuse.

Design

This quality improvement (QI) project used …

A Qualitative Case Study Research Investigation Of Youth Outcomes During An Appalachian Water-Quality Citizen Science Program, Jessica Kaplan

Graduate Theses, Dissertations, and Problem Reports (ETD)

Citizen science has grown in the past decades to not only include everyday people in research, but also varying levels of engagement with diverse opportunities for participant learning and growth. However, few studies reflect the actual learning outcomes of educational citizen science specifically in youth. This single case study research study focuses on assessing learning and other outcomes of an environmental education, collaborative citizen science program with youth in Morgantown, West Virginia. In this study, a water quality monitoring citizen science program focused on Deckers Creek in Morgantown, WV was adapted for a high school afterschool club. Potential outcomes of …

Representation Learning With Adversarial Latent Autoencoders, Stanislav Pidhorskyi M.S.

Graduate Theses, Dissertations, and Problem Reports (ETD)

A large number of deep learning methods applied to computer vision problems require encoder-decoder maps. These methods include, but are not limited to, self-representation learning, generalization, few-shot learning, and novelty detection. Encoder-decoder maps are also useful for photo manipulation, photo editing, superresolution, etc. Encoder-decoder maps are typically learned using autoencoder networks.
Traditionally, autoencoder reciprocity is achieved in the image-space using pixel-wise
similarity loss, which has a widely known flaw of producing non-realistic reconstructions. This flaw is typical for the Variational Autoencoder (VAE) family and is not only limited to pixel-wise similarity losses, but is common to all methods relying upon …

Programming Of Floating-Gate Transistors For Nonvolatile Analog Memory Array, Haifa Abulaiha

Graduate Theses, Dissertations, and Problem Reports (ETD)

Since they were introduced, floating-gate (FG) transistors have been used as non-volatile digital memory. Recent research has shown that floating-gate transistors can be successfully used as analog memory, specifically as programmable voltage and current sources. However, their proliferation has been limited due to the complex programming procedure and the complex testing equipment. Analog applications such as field-programmable analog arrays (FPAAs) require hundreds to thousands of floating-gate transistors on a single chip which makes the programming process even more complicated and very challenging. Therefore, a simplified, compact, and low-power scheme to program FGs are necessary. This work presents an improved version …

Searches For Fast Radio Bursts Using Machine Learning, Devansh Agarwal

Graduate Theses, Dissertations, and Problem Reports (ETD)

Fast Radio bursts (FRBs) are enigmatic astrophysical events with millisecond durations and flux densities in the range 0.1-100 Jy, with the prototype source discovered by Lorimer et al. (2007). Like pulsars, FRBs show the characteristic inverse square sweep in observing frequency due to propagation through an ionized medium. This effect is quantified by the dispersion measure (DM). Unlike pulsars, FRBs have anomalously high DMs, which are consistent with an extragalactic origin. Over 100 FRBs have been published at the time of writing, and 13 have been conclusively identified with host galaxies with spectroscopically determined redshifts in the range 0.003 ≤ …

The Fight Is Still On: An Ethical Analysis Of The American Civil Liberties Union’S Partisan Rhetoric In The Trump Era, Emily Charlotte Gerber

Graduate Theses, Dissertations, and Problem Reports (ETD)

The 2016 U.S. presidential election of Donald Trump generated a newfound surge in political advocacy that greatly benefitted certain nonprofits and grassroots organizations. One of these organizations was the American Civil Liberties Union, a nonpartisan nonprofit dedicated to protecting and defending civil liberties and rights in the U.S. The ACLU received an unprecedented number of donations following Election Day and has since pursued an aggressive campaign against President Donald Trump.

In order to explore this phenomenon, this thesis analyzed the ACLU’s rhetoric between Presidents George W. Bush and Donald Trump (both Republicans) and between Presidents Barack Obama (Democrat) and Donald …

Memories Of Judgment: Constructing The Icty's Legacies, Diane Orentlicher

Scholarly Articles in Law Reviews & Journals

As the title of this symposium reflects, a critically important dimension of the Tribunal's legacy is its role in understanding the war and genocide in Bosnia. In my remarks, I want to drill down on the word "understanding," one of the most complex facets of the ICTY's legacy. In brief, I will make four points. The first is that the ICTY's expected contribution to understanding the 1990s conflict in Bosnia and the atrocities associated with that conflict was deeply important to many individuals whom I have interviewed in Bosnia-Herzegovina, as well as in Serbia, about the ICTY's impact in their …

The Use Of Differing Verb Types In The Oral Narratives Of School-Age Children, Allison Ann Switzer

Graduate Theses, Dissertations, and Problem Reports (ETD)

The aim of this project was to examine the use of action, metacognitive, and metalinguistic verbs in narratives relative to age-related growth for children with typical language and their peers with a language-based disorder. While limited information is known about the use of these differing verb types, there is evidence to show that metacognitive and metalinguistic verbs are less salient than action verbs, and therefore have a longer trajectory of acquisition. The oral narratives of 84 typically developing students were coded for occurrences of action verbs, metacognitive verbs, and metalinguistic verbs to obtain a total use as well as to …

Exploring The Challenges Of Social Integration Within An Upper-Level Public Relations Classroom, Tabitha Hayley Dyer

Graduate Theses, Dissertations, and Problem Reports (ETD)

Despite three decades of literature that has explored the gender imbalance of public relations at a professional level, there is a dearth of information addressing if or how these experiences are informed at a collegiate level. Accordingly, this study examines if the gender imbalance impacts students in the upper-level public relations classroom, and the similarities and differences exist between other single-gender dominant programs including nursing and Science, Technology, Engineering, and Mathematics (STEM) using three dimensions (i.e., role strain, teamwork, and overall social environment) as a comparison. Using qualitative in-depth interview data collected from 13 junior- and senior-standing public relations students …

Respectable Women, Ambitious Men: Gender And Family Networks In Victorian Sheffield, Autumn Mayle

Graduate Theses, Dissertations, and Problem Reports (ETD)

“Respectable Women, Ambitious Men: Gender and Family Networks in Victorian Sheffield” offers a family study of Nonconformist manufacturers in nineteenth-century Sheffield through several thematic case studies on such subjects as gender, family networks and businesses, bankruptcy, piety, and charitable work. This project focuses on the Reads, a family of middle-class Congregationalist smelters who owned a smelting works, named Read & Co., in nineteenth-century Sheffield. The Reads’ experiences contribute to recent scholarship on gender and kinship studies by addressing the role of nineteenth-century conceptions of masculinity and femininity on family, charity, and business and the enduring influence of nuclear families and …

Becoming The Lion's Historian, Khadija-Awa Diop

Graduate Theses, Dissertations, and Problem Reports (ETD)

This professional project examines the ways in which French colonial documentaries were used in conjunction with governmental legislation to enforce dominant narratives and repress marginalized perspectives about the nature of colonialism and the roles of the French and West Africans in its execution. Through the limitations and powers of documentary filmmaking, this project explores the ways in which counter narratives can allow media professionals today to remedy the one sided dominant narratives about marginalized communities that have existed for decades. The culmination of this project is in the creation of a documentary treatment and sizzle reel that will be the …

Oxygen Transport Kinetics Of Surface Modified Mixed Conductor (La0.60sr0.40)0.95co0.20fe0.80o3-X As Solid Oxide Fuel Cell Cathode, Manuel Serrano Laguna

Graduate Theses, Dissertations, and Problem Reports (ETD)

The oxygen transport kinetics of the electrodes of Solid Oxide Fuel Cells (SOFC) are critical properties to achieve higher efficiencies in the cell. (La0.60Sr0.40)0.95Co0.20Fe0.80O3-x (LSCF) is a mixed ion-electron conductor material that is expected to be optimized and utilized as the cathode of the SOFC’s. The reason for LSCF to be considered as the next cathode material for SOFC is due to its high ionic and electronic conductivities, and high oxygen transport kinetics. Additionally, to the excellent properties that this material offers, it has been seen that the kinetic properties of the material can be further optimized by adding a …

Monotonic Response Of Rc Exterior Beam-Column Joints Reinforced With Filler-Modules And Frp Composite Wraps/Gussets, Praveen Kumar Reddy Majjigapu

Graduate Theses, Dissertations, and Problem Reports (ETD)

A review of post-earthquake reconnaissance studies revealed that reinforced concrete (RC) structures, designed and built before the development of Uniform Building Code (UBC) seismic design guidelines in 1976, have suffered complete collapse or severe damages due to the brittle failure of exterior beam-column joints. Over the past 50 years, several studies were conducted to strengthen exterior joints of in-service structures, with limited emphasis on developing simple, economic and durable repair strategies to improve energy absorption through large inelastic joint deformations. Even less emphasis was devoted to developing repair procedures that minimize stress-concentrations at joint corners and enhancing the strength, ductility, …

Accuracy Of Blx And Blt Guided Implants In The Edentulous Maxilla: An In Vivo Study, Benjamin Andrew Kordusky

Graduate Theses, Dissertations, and Problem Reports (ETD)

Objectives: To determine the accuracy of dental implants placed using a dual scan CBCT protocol with a SLA 3D printed mucosa supported surgical guide using a flapless surgical approach with regard to sleeve position, type of implant, and regional location in the maxillary arch.

Methods: Nine patients received 4 dental implants utilizing a fully guided, flapless approach with a mucosa supported SLA surgical guide with 3 fixation pins. Implants were immediately loaded using an attachment placed in an existing Maxillary complete denture. Accuracy of implant positions were evaluated by the Treatment Evaluation module of coDiagnostiX (DentalWings, Montreal, Canada). Statistical analysis …

Collaborative Entrepreneurship And Building Small Business Communities In The Nigerian Fashion Design Industry, Damilola T. Fasinu

Graduate Theses, Dissertations, and Problem Reports (ETD)

A critical part of being an entrepreneur is the ability to work with others. Researchers who explore entrepreneurship acknowledge collaboration and information sharing as key as more obvious skills such as opportunity recognition and determination. Collaboration allows a firm to be entrepreneurial and constantly innovative by exploring new markets. Continuous innovation and market exploration are the foundation of collaboration. Entrepreneurship is a critical factor in the growth of developing countries, as it enables a country to grow economically and encourages sustainable business activity. Therefore, this study explores the collaborative entrepreneurship of communities of some small businesses in Nigeria for their …