Digital Commons Network^™

Heritability Enrichment Of Immunoglobulin G N-Glycosylation Relevant Genes In Specific Tissues, Xingang Li

Theses: Doctorates and Masters

Genome-wide association studies (GWAS) have identified over 60 genetic loci associated with IgG N-glycosylation; however, the causal genes and their abundance in relevant tissues are uncertain. In this study, firstly, I leveraged data from GWAS summary statistics for 8,090 Europeans, and large-scale expression quantitative trait loci (eQTL) data from the genotype-tissue expression of 53 types of tissues (GTEx v7), to derive a linkage disequilibrium score for the specific expression of genes (LDSC-SEG) and conduct a transcriptome-wide association study (TWAS). I identified 55 genes whose predicted levels of expression were significantly associated with IgG Nglycosylation in 14 tissues with regard to …

The Solo Piano Sonatas Of Cipriani Potter (1792-1871): An Analysis, Reappraisal, And Historical Performance, Jordan Proctor

Theses: Doctorates and Masters

The solo piano sonatas (Op. 1, 3, and 4) of once eminent English pianist/composer Cipriani Potter (1792-1871) are a collection of works that have for the most part fallen into obscurity. Potter produced three such sonatas in his lifetime, each at approximately the same time during his educational trip to Vienna between 1817 and 1818. Potter was much celebrated in his own time as a virtuoso pianist, teacher, and eventual principal at the Royal Academy of Music, and as an editor of the works of Mozart and Beethoven amongst others. This study examines Potter’s sonatas in light of both modern …

Overestimating One’S “Green” Behavior: Better-Than-Average Bias May Function To Reduce Perceived Personal Threat From Climate Change, Zoe Leviston, Hannah V. Uren

Research outputs 2014 to 2021

The actions of others, and what others approve of, can be a powerful tool for promoting proenvironmental behavior. A potential barrier to the utility of social norms, however, are cognitive biases in how people perceive themselves and others, including the better‐than‐average effect. This effect describes the tendency for people to think they are exceptional, especially when compared with their peers. To investigate the role of the better‐than‐average effect in proenvironmental behavior, we administered questions as part of a larger online survey of 5,219 nationally representative Australians. Participants were asked to report whether they engaged in a list of 21 proenvironmental …

A Broad Autism Phenotype Expressed In Facial Morphology, Diana Weiting Tan, Murray T. Maybery, Syed Zulqarnain Gilani, Gail A. Alvares, Ajmal Mian, David Suter, Andrew J. O. Whitehouse

Research outputs 2014 to 2021

Autism spectrum disorder is a heritable neurodevelopmental condition diagnosed based on social and communication differences. There is strong evidence that cognitive and behavioural changes associated with clinical autism aggregate with biological relatives but in milder form, commonly referred to as the ‘broad autism phenotype’. The present study builds on our previous findings of increased facial masculinity in autistic children (Sci. Rep., 7:9348, 2017) by examining whether facial masculinity represents as a broad autism phenotype in 55 non-autistic siblings (25 girls) of autistic children. Using 3D facial photogrammetry and age-matched control groups of children without a family history of ASD, we …

Effectiveness Of A Structured, Framework-Based Approach To Implementation: The Researching Effective Approaches To Cleaning In Hospitals (Reach) Trial, Lisa Hall, Nicole M. White, Michelle Allen, Alison Farrington, Brett G. Mitchell, Katie Page, Kate Halton, Thomas V. Riley, Christian A. Gericke, Nicholas Graves, Anne Gardner

Research outputs 2014 to 2021

BACKGROUND: Implementing sustainable practice change in hospital cleaning has proven to be an ongoing challenge in reducing healthcare associated infections. The purpose of this study was to develop a reliable framework-based approach to implement and quantitatively evaluate the implementation of evidence-based practice change in hospital cleaning. DESIGN/METHODS: The Researching Effective Approaches to Cleaning in Hospitals (REACH) trial was a pragmatic, stepped-wedge randomised trial of an environmental cleaning bundle implemented in 11 Australian hospitals from 2016 to 2017. Using a structured multi-step approach, we adapted the integrated Promoting Action on Research Implementation in Health Services (i-PARIHS) framework to support rigorous and …

Understanding Early-Stage Firm Performance: The Explanatory Role Of Individual And Firm Level Factors, Pi-Shen Seet, Noel Lindsay, Fredric Kropp

Research outputs 2014 to 2021

Purpose:

This study presents and validates a theoretical model linking individual characteristics of the founding or lead innovative entrepreneur of a start-up venture – the entrepreneur’s values, entrepreneurial attitudes and entrepreneurial self-efficacy – to the firm’s entrepreneurial orientation (EO) and market orientation (MO) and, ultimately, to firm performance.

Design/methodology/approach:

We conducted a survey on a stratified random sample of founders of early-stage South Australian micro- and small enterprises with a response rate of 24% (N 5 204). Structural equation modelling was used to evaluate the model.

Findings:

The study found that there is a significant relationship between the individual lead …

Green Human Resource Management: A Two-Study Investigation Of Antecedents And Outcomes, Azadeh Shafaei, Mehran Nejati, Yusmani Mohd Yusoff

Research outputs 2014 to 2021

Purpose

The study aimed to provide insights on antecedent and outcome of green HRM at the organisational level and the outcome of green HRM at the individual level. It also sought to examine the mechanism through which green HRM would lead to employees’ positive outcome.

Design/methodology/approach

A quantitative study design using a two-study approach was employed to collect and analyse the data. For study 1, 206 hotels from Malaysia were included in analysis at the organisational level, while in study 2 at the individual level, 508 employees from different sectors provided insights through an online questionnaire. For both studies, partial …

Integrating And Maintaining Automated External Defibrillators And Emergency Planning In Community Sport Settings: A Qualitative Case Study, Lauren V. Fortington, Sheree Bekker, Caroline Finch

Research outputs 2014 to 2021

Introduction:

A voluntary State Government-led programme in Victoria, Australia ‘Defibrillators for Sporting Clubs and Facilities Program’ ran from 2015 to 2019, broadly aimed at increasing access to automated external defibrillators (AEDs), together with a greater number of community members trained for management of medical emergencies. This study aimed to understand whether participating sport clubs/facilities had successfully integrated an AED and medical planning with other club/facility safety practices, 12 months after delivery of the programme.

Methods:

This was a qualitative case study of 14 sport clubs/facilities in Victoria, Australia in 2017, underpinned by the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) framework. …

How Can School Libraries Support Student Wellbeing? Evidence And Implications For Further Research, Margaret Merga

Research outputs 2014 to 2021

Concern about student wellbeing and related mental health is a global issue, and schools are increasingly expected to support student wellbeing. While the focus on libraries and wellbeing in research is more commonly on public libraries, school libraries can also play an important supportive role in this regard. Robust research evidence is needed from school library contexts to support targeted advocacy in order to enhance student wellbeing. This paper explores how school libraries may support student wellbeing by operating as safe spaces for young people, promoting and resourcing mental health and wellbeing initiatives, and supporting and promoting bibliotherapeutic practices and …

Let The Data Speak: Using Rigour To Extract Vitality From Qualitative Data, Alistair J. Campbell

Research outputs 2014 to 2021

Qualitative data can be gathered from an array of rich sources of research information. One of the popular ways to collect this data is by interviewing a range of experts on the topic, followed by transcription, resulting in a database of written documents, often supplemented by other documented data that informs the topic. Thematic or Content Analysis can then be used to explore the data and identify themes of meaning that enlighten the research topic, with the themes being gathered into nodes. The researcher now has an array of nodes, which needs to be organised into a coherent model, and …

Whole Genome Landscapes Of Uveal Melanoma Show An Ultraviolet Radiation Signature In Iris Tumours, Peter A. Johansson, Kelly Brooks, Felicity Newell, Jane M. Palmer, James S. Wilmott, Antonia L. Pritchard, Natasa Broit, Scott Wood, Matteo S. Carlino, Conrad Leonard, Labros T. Koufariotis, Vaishnavi Nathan, Aaron B. Beasley, Madeleine Howlie, Rebecca Dawson, Helen Rizos, Chris W. Schmidt, Georgina V. Long, Hayley Hamilton, Jens F. Kiilgaard, Timothy Isaacs, Elin S. Gray, Olivia J. Rolfe, John J. Park, Andrew Stark, Graham J. Mann, Richard A. Scolyer, John V. Pearson, Nicolas Van Baren, Nicola Waddell, Karin W. Wadt, Lindsay A. Mcgrath, Sunil K. Warrier, William Glasson, Nicholas K. Hayward

Research outputs 2014 to 2021

Uveal melanoma (UM) is the most common intraocular tumour in adults and despite surgical or radiation treatment of primary tumours, ~50% of patients progress to metastatic disease. Therapeutic options for metastatic UM are limited, with clinical trials having little impact. Here we perform whole-genome sequencing (WGS) of 103 UM from all sites of the uveal tract (choroid, ciliary body, iris). While most UM have low tumour mutation burden (TMB), two subsets with high TMB are seen; one driven by germline MBD4 mutation, and another by ultraviolet radiation (UVR) exposure, which is restricted to iris UM. All but one tumour have …

Factors Influencing Carbon Stocks And Accumulation Rates In Eelgrass Meadows Across New England, Usa, A. B. Novak, M. C. Pelletier, P. Colarusso, J. Simpson, M. N. Gutierrez, A. Arias-Ortiz, M. Charpentier, Pere Masque, P. Vella

Research outputs 2014 to 2021

Increasing the protection of coastal vegetated ecosystems has been suggested as one strategy to compensate for increasing carbon dioxide (CO2) in the atmosphere as the capacity of these habitats to sequester and store carbon exceeds that of terrestrial habitats. Seagrasses are a group of foundation species that grow in shallow coastal and estuarine systems and have an exceptional ability to sequester and store large quantities of carbon in biomass and, particularly, in sediments. However, carbon stocks (Corg stocks) and carbon accumulation rates (Corg accumulation) in seagrass meadows are highly variable both spatially and temporally, making it difficult to extrapolate this …

Establishing International Best Practice Principles For Impact Assessment Teaching And Training, Angus Morrison-Saunders, Jenny Pope, Megan Jones

Research outputs 2014 to 2021

Best Practice Principles for Impact Assessment (IA) Teaching and Training were developed for the International Association for Impact Assessment (IAIA). Research conducted throughout 2018 and 2019 encompassed seven iterative steps: an initial practitioners workshop; comprehensive review of 40 years of literature on teaching IA; initial survey of teachers and trainers; follow-up interviews; development of draft set of principles; final survey of the importance of the draft principles to university teachers and professional development trainers in IA; and a final workshop at IAIA19. The resulting principles are grouped in relation to content (what is taught), pedagogy (how content is taught) and …

Perceived Barriers To Healthcare Utilization Among Jordanian Families: A Family Centered Approach, Abeer M. Shaheen, Khaldoun M. Hamdan, Maha Alkaid Albqoor, Diana H. Arabiat

Research outputs 2014 to 2021

Aim: This study aimed to understand the barriers to health services utilization by Jordanian families.

Background: Access to quality healthcare services is a significant issue facing healthcare systems. Healthcare systems must identify and apply measures to overcome barriers that face utilizing health services and thus increase clients' satisfaction.

Methods: A cross-sectional qualitative research design was used in this study. Semi-structured interviews were conducted with twenty-five families to elicit the model of health services barriers.

Results: The analysis of the family interviews led to four main themes related to health services barriers: service system, structural/physical barriers, equipment and medication, and staff …

Efficacy Of A Weight Loss Program Prior To Robot Assisted Radical Prostatectomy In Overweight And Obese Men With Prostate Cancer, Rebekah Wilson, Tom Shannon, Emily Calton, Daniel A. Galvao, Dennis Taaffe, Nicolas H. Hart, Philippa Lyons-Wall, Robert U. Newton

Research outputs 2014 to 2021

Background

Obesity in prostate cancer patients is associated with poor prostate-cancer specific outcomes. Exercise and nutrition can reduce fat mass; however, few studies have explored this as a combined pre-surgical intervention in clinical practice.

Purpose

This study examined the efficacy of a weight loss program for altering body composition in prostate cancer patients prior to robot assisted radical prostatectomy (RARP).

Methods

A retrospective analysis of 43 overweight and obese prostate cancer patients, aged 47–80 years, who completed a very low-calorie diet (~3000–4000 kJ) combined with moderate-intensity exercise (90 min/day) prior to RARP. Whole body and regional fat mass (FM) and …

Sars-Cov-2 Updates In A West African Population And Precautionary Measures For Sustaining Quality Antenatal Care Delivery, Emmanuel Komla Senanu Morhe, Enoch Odame Anto, David Anthony Coall, Eric Adua, Alexander Yaw Debrah, Otchere Addai-Mensah, Michael Owusu, William K.B.A. Owiredu, Christian Obirikorang, Emmanuel Akomanin Asiamah, Emmanuel Acheampong, Evan Adu Asamoah, Lydia Abradu, Agartha Odame Anto, Youxin Wang, Haifeng Hou, Wei Wang

Research outputs 2014 to 2021

No abstract provided.

Knowledge Management In The Pharmaceutical Industry: Between Academic Research And Industry Regulations, Ahmed Ramy, Mohamed Af Ragab, Amr Arisha

Articles

The pharmaceutical sector is one of the pillars of the world’s economy. A significant proportion of its value lies in intellectual assets generated through continuous innovation and lengthy development cycles within a strictly regulated environment. The purpose of this paper is to address the gap between knowledge management (KM) as an expanding academic discipline in the pharmaceutical industry and at the same time a growing regulatory expectation. A systematic review of 137 refereed KM articles revealed six empirical research themes in the pharmaceutical industry. In a subsequent step, the discovered themes and subthemes were compared with the extant regulatory expectations …

Pre-Intermediate Accounting, Natasha Ware

Syllabus Repository

No abstract provided.

Importance Of Data Distribution On Hive-Based Systems For Query Performance: An Experimental Study, Hilmi Egemen Ciritoglu, John Murphy, Christina Thorpe

Articles

SQL-on-Hadoop systems have been gaining popularity in recent years. One popular example of SQL-on-Hadoop systems is Apache Hive; the pioneer of SQL-on-Hadoop systems. Hive is located on the top of big data stack as an application layer. Besides the application layer, the Hadoop Ecosystem is composed of 3 different main layers: storage, the resource manager and processing engine. The demand from industry has led to the development of new efficient components for each layer. As the ecosystem evolves over time, Hive employed different execution engines too. Understanding the strengths of components is very important in order to exploit the full …

Advanced Accounting: Framework & Special Reporting, Christopher M. Fairchild

Syllabus Repository

No abstract provided.

Advanced Accounting: Framework & Special Reporting, Christopher M. Fairchild

Syllabus Repository

No abstract provided.

Advanced Accounting: Acquisitions & Consolidations, Christopher M. Fairchild

Syllabus Repository

No abstract provided.

Advanced Accounting: Acquisitions And Consolidations, Steelman Library

Syllabus Repository

No abstract provided.

Accounting Internship, Christopher M. Fairchild

Syllabus Repository

No abstract provided.

Accounting Internship, Christopher M. Fairchild

Syllabus Repository

No abstract provided.

Biology I Lab, Melba D. Horton

Syllabus Repository

No abstract provided.

Biology Ii Lab, Melba D. Horton

Syllabus Repository

No abstract provided.

General Genetics Lab, Steelman Library, Melba Horton Dr

Syllabus Repository

No abstract provided.

Research In Biological Sciences, Steelman Library, Melba Horton

Syllabus Repository

No abstract provided.

Repatriating The Canaanite Woman In The Gospel Of Matthew, Cedric Vine

Andrews University Seminary Studies (AUSS)

This study argues that Matthew’s replacement of Mark’s “Gentile of Syrophoenician origin” with a “Canaanite woman” (Mark 7:26; Matt 15:22) is part of a wider narrative strategy to portray the land of Israel and its cities as a new Sodom, a new Canaan, a new Egypt, and a new Babylon. The study employs Dale Allison’s six intertextual devices (explicit statement, inexplicit citation or borrowing, similar circumstances, key words or phrases, similar narrative structure, and word order, syllabic sequence, and poetic resonance) to demonstrate a consistent authorial intention while identifying contemporary or near contemporary sources that would affirm the likelihood that …