Digital Commons Network^™

Nanoceria Distribution And Effects Are Mouse-Strain Dependent, Robert A. Yokel, Michael T. Tseng, D. Allan Butterfield, Matthew L. Hancock, Eric A. Grulke, Jason M. Unrine, Arnold J. Stromberg, Alan K. Dozier, Uschi M. Graham

Pharmaceutical Sciences Faculty Publications

Prior studies showed nanoparticle clearance was different in C57BL/6 versus BALB/c mice, strains prone to Th1 and Th2 immune responses, respectively. Objective: Assess nanoceria (cerium oxide, CeO₂ nanoparticle) uptake time course and organ distribution, cellular and oxidative stress, and bioprocessing as a function of mouse strain. Methods: C57BL/6 and BALB/c female mice were i.p. injected with 10 mg/kg nanoceria or vehicle and terminated 0.5 to 24 h later. Organs were collected for cerium analysis; light and electron microscopy with elemental mapping; and protein carbonyl, IL-1β, and caspase-1 determination. Results: Peripheral organ cerium significantly increased, generally more …

Immunity From Suit For International Organizations: The Judiciary's New Que Of Separating Lawsuit Sheep From Lawsuit Goats, Ylli Dautaj

Indiana Journal of Global Legal Studies

I. Introduction

II. Immunity from Suit in Public International Law

(A) Sovereign Immunity

(i) Sources of Sovereign Immunity

(ii) Legal Theory on Sovereign Immunity

(iii) Doctrinal Evolution of Sovereign Immunity

(B) Jurisdictional Immunity for International Organizations

(C) Sovereign Immunity and Immunity for International Organizations

Domestically

III. Jam v. Int'l Finance Corporation:

A New Dawn for International Organizations in the United States

(A) Jam v. Int'l Finance Corporation: Majority View

(B) Jam v. Int'l Finance Corporation: Dissenting Opinion by Justice Breyer

IV. The Exception that Proves but does not Swallow the rule on Virtually

Absolute Immunity: Criticism of the Majority in …

Authority And The Globalisation Of Inclusion And Exclusion: Author Meets Readers, Hand Lindahl, Christine Bell Prof, Friedrich Kratochwil, Hans-W. Micklitz, Carlos Thiebaut, Bert Van Roermund

Indiana Journal of Global Legal Studies

Authority is written against the background of intense resistance to globalization processes by a range of political movements and grassroots organizations. These processes are complex and have a variety of dimensions. One of these is the emergence of global legal orders, which I define, in a rough and ready manner, as relatively autonomous legal orders that claim or aspire to claim global validity for themselves. They too-most obviously the World Trade Organization (WTO)-are the butt of resistance. Whatever its forms and aspirations, resistance to globalization is fueled by their peculiar dynamic. Indeed, emergent global legal orders spawn massive exclusion when …

Predicting And Mapping Plethodontid Salamander Abundance Using Lidar-Derived Terrain And Vegetation Characteristics, Marco Antonio Contreras, Wesley A. Staats, Steve J. Price

Forestry and Natural Resources Faculty Publications

Aim of the study: Use LiDAR-derived vegetation and terrain characteristics to develop abundance and occupancy predictions for two terrestrial salamander species, Plethodon glutinosus and P. kentucki, and map abundance to identify vegetation and terrain characteristics affecting their distribution.

Area of study: The 1,550-ha Clemons Fork watershed, part of the University of Kentucky’s Robinson Forest in southeastern Kentucky, USA.

Materials and methods: We quantified the abundance of salamanders using 45 field transects, which were visited three times, placed across varying soil moisture and canopy cover conditions. We created several LiDAR-derived vegetation and terrain layers and used these …

Bong Joon-Ho’S Transnational Challenge To Eurocentrism, Lisa - Marie Spaethen

Film and Media Studies (MA) Theses

Through a narrative analysis of three of Bong Joon-ho’s films: The Host (2006), Snowpiercer (2013), and Okja (2017), this thesis explores the impact of global media flow of transnational cinema, foregrounding its potential to convey broader (but more effective) social and ecological political messages through its wider reach to audiences. Each film selected highlights a specific aspect of transnational cinema – postcolonial transnationalism (Shohat and Stam, 1994), transnational odor (Koichi Iwabuchi, 2002), and ecocinema transnationalism (Kääpä Pietari, 2013) - illustrating the fluidity of cinema in the 21st century and further, the unique position Netflix holds in our contemporary mediascape as …

Paleoenvironment Reconstruction Of The Eocene Southeastern Tethys Using Geochemistry Of Sedimentary Rocks, Liliana CalderóN Convers

Theses, Dissertations and Culminating Projects

The Early Eocene hyperthermals are a series of transient global warming events that occurred between 54.09 and 52.63 Ma, and are considered as ancient analogues for future climate change. These hyperthermal events are well studied in the deep sea sites, but have not been investigated in the eastern Tethys Ocean. Here, we report new major and trace element geochemistry and stable carbon isotope data of the Early Eocene strata deposited in a shallow marine foreland basin prior to the main stage of India-Asian continent collision at Qumiba section in the Tingri County, southern Tibet. These geochemical data are used to …

Transcriptomic Identification Of Venom Candidates In The Clinging Jellyfish Gonionemus Vertens, Alorah D. Bliese

Theses, Dissertations and Culminating Projects

Gonionemus vertens appearances and stings have been increasing internationally. The medusae of this hydrozoan are small, having an average bell diameter of 2 cm, and are noted for their potent stings that can lead to systemic pain, hospitalization, and disrupted neurocognitive function. They are typically found among algae and in eelgrass beds during the summer months when the population peaks, thus posing a seasonal public health concern for those participating in recreational water activities. To explore the nature of this species’ toxic sting, transcriptome libraries were constructed from poly A⁺ mRNA isolated from mature individuals and sequenced on an …

Factors Affecting Clutch Size In A Population Of Red-Backed Salamander (Plethodon Cinereus) In Northwestern New Jersey, Veronica Lynn Puza

Theses, Dissertations and Culminating Projects

The salamander family Plethodontidae is known for being an indicator of environmental health and has been labeled as the “canary in the coal mine” of forest ecosystems (Urban et al. 2014). One of the most widely distributed and commonly studied plethodontid species is the red-backed salamander (RBS, Plethodon cinereus). Populations of P. cinereus will be influenced by different variables within the environment including temperature, humidity, and leaf litter. Fundamental data on populations of P. cinereus must be gathered before we can understand how these intercorrelated variables will influence P. cinereus distribution and demographics. In this study I aimed to gather …

A Community Of Learning In An Elementary School Mathematics Classroom, Megan Louise Roeder

Theses, Dissertations and Culminating Projects

The goal of this study was to investigate opportunities for cultivating a community of learning in an elementary school mathematics classroom using four guiding principles for productive disciplinary engagement. A community of learning involves teachers and students participating equally in negotiating, sharing, and producing knowledge as co-learners, coteachers, and co-collaborators in the classroom. Characteristics of a community of learning align with effective teaching and learning practices described by national governing bodies and researchers in the field of mathematics education. The essence of a community of learning is beneficial in an elementary mathematics classroom because it invokes deep learning about disciplinary …

The Role Of Covariational Reasoning In Pre-Service Teachers’ Meanings For Quadratic And Exponential Relationships, Madhavi Vishnubhotla

Theses, Dissertations and Culminating Projects

Researchers have indicated that students have difficulties recognizing quadratic and exponential change and do not maintain productive meanings for these relationships. Other researchers have documented that students are capable of developing productive meanings for mathematical ideas via covariational reasoning. This dissertation reports the results of an investigation into ways in which preservice teachers can leverage covariational reasoning to develop meanings for quadratic and exponential relationships. I collected data by engaging two preservice teachers in semi-structured clinical interviews and a semester long teaching experiment. My analyses reveal that whereas in the pre-interviews, the participants did not have meanings that supported differentiating …

Studies Toward The Synthesis Of A Novel Diamine Scaffold, Joseph Edward Quinlan Iii

Theses, Dissertations and Culminating Projects

The orexin system in humans contains receptors Orexin 1 (OX1) and Orexin 2 (OX2). These receptors are involved in numerous physiological processes including wake/sleep cycling, energy homeostasis, and motivation/reward. In scientific literature, it is known that antagonism of these receptors exhibits therapeutic effects in the realm of cocaine and alcohol addiction, as well as sleep disorders. On the market today exist drugs for treatment of sleep disorders through orexin receptor antagonization. Here we report a synthesis toward novel conformationally rigid antagonists of the orexin receptor system that may provide improved affinity and/or selectivity compared to known compounds. We report the …

Benthic Biological Monitoring Of The Elizabeth River Watershed (1999 And 2019), Daniel M. Dauer

Elizabeth River Reports

Executive Summary

A study of the macrobenthic communities of the Elizabeth River watershed was conducted in summer 1999 and again in summer 2019 – a 20-year span. The primary objective of the Benthic Biological Monitoring Program of the Elizabeth River watershed was to characterize the ecological condition of regional areas of the tidal waters of the Elizabeth River watershed as indicated by the structure of the benthic communities. These characterizations are based upon application of the Benthic Index of Biotic Integrity (BIBI) developed for the Chesapeake Bay to five primary strata - the Mainstem of the river, the Lafayette River, …

Exploring Experiences With Social Disorganization In Denver Communities, Tiffanie Pham

Master's Theses

Social disorganization theory states that individuals residing in disadvantaged communities are more likely to engage in delinquency and criminality due to the elements the individuals experience (Shaw & McKay, 1969). More specifically, social disorganization theory refers to the failure of the community to fully understand and acknowledge the common goals or solve any issues that the community might be experiencing (Kubrin & Weitzer, 2003). Utilizing social disorganization theory, specifically, the family disruption and poverty elements, the current literature focuses on individuals who reside in disadvantaged communities in Denver, Colorado. By using the qualitative approach, this study relied on in-depth interviews …

How Human-Centered Design Affects The Workplace, Alexandra Brigham

Master's Theses

This qualitative study was designed to explore the impact a workplace environment has on employees’ well-being and productivity. The research identified the themes of flattening, perception, unflattening, and well-being from a multidisciplinary approach including art education, fine art, architecture, medicine, philosophy, and science. Flatness is a state, a behavior that occurs when human perception and consciousness are narrowed, blocking sensory information that is not pertinent to a current task. Behavior that is perpetuated by ingrained societal systems and exacerbated by personal, professional, and financial stressors that can impact the human experience. Flattened areas are addressed in this study through a …

Transcriptome Analyses In Bv2 Microglial Cells Following Treatment With Amino-Terminal Fragments Of Apolipoprotein E, Tanner B. Pollock, Giovan N. Cholico, Tarun Suresh, Erica S. Stewart, Madyson M. Mccarthy, Troy T. Rohn

Biology Faculty Publications and Presentations

Despite the fact that harboring the apolipoprotein E4 (APOE4) allele represents the single greatest risk factor for late-onset Alzheimer’s disease (AD), the exact mechanism by which ApoE4 contributes to disease progression remains unknown. Recently, we demonstrated that a 151 amino-terminal fragment of ApoE4 (nApoE4_1–151) localizes within the nucleus of microglia in the human AD brain and traffics to the nucleus causing toxicity in BV2 microglia cells. In the present study, we examined in detail what genes may be affected following treatment by nApoE4_1–151. Transcriptome analyses in BV2 microglial cells following sublethal treatment with nApoE4 …

Effect Of Training Phase On Physical And Physiological Parameters Of Male Powerlifters, Daniel A. Hackett, Guy C. Wilson, Lachlan Mitchell, Marjan Mosalman Haghighi

Open Access archive

Longitudinal research on training and dietary practices of natural powerlifters is limited. This study investigated the effect of phases of training on physical and physiological parameters in male natural powerlifters. Nine participants completed testing at two time points: (i) preparatory phase (~3 months prior to a major competition) and (ii) competition phase (1–2 weeks from a major competition). No significant changes between training phases were found for muscle strength and power. A trend for significance was found for decreased muscle endurance of the lower body (−24.4%, p = 0.08). A significant increase in leg lean mass was found at the …

Nebline, August 2020

NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County

Be an Active Family with Outdoor Activities

EXTENSION OFFICE OPEN

Recipes of the month

What You Need to Know About Having a Well Drilled

Almost Time for Fall Lawn Seeding

Chiggers: Itching in all the Wrong Places

Collect – Share – Practice: Family Emergency Communication Plans

August Blooming Perennial Flowers

Garden Guide: Things to Do This Month

Creating Reading Routines During the Summer Months

HEART OF 4-H

4-H Youth and Volunteers Sew 1,789 Hats and Masks for Bryan Health

4-H’ers Problem Solve Real-Life Situations at County Life Challenge

Virtual State Public Speaking Contest Results

State Fair to Focus on Showcasing …

Isotopic Analysis Of Human Migration Among The Ancient Maya Of Ambergris Caye, Belize, Rachel L. Smith

Electronic Theses and Dissertations

This thesis uses the isotopic composition of tooth enamel from two Maya sites on Ambergris Caye Belize, to identify basic patterns of population movement among the Classic period Maya. Three individuals from San Juan and ten individuals from Chac Balam will shed light on the origin of individuals buried at the sites, including those with nonlocal grave goods. Strontium and oxygen isotope values provide new information on Maya coastal populations and suggest that at least one individual with a distinct body position had a nonlocal origin. Carbon isotope values reveal a childhood diet related to, but not the same as, …

Reduced Vip Expression Affects Circadian Clock Function In Vip-Ires-Cre Mice (Jax 010908), Deborah A.M. Joye, Kayla Rohr, Danielle Keller, Thomas Inda, Adam Telega, Harshida Pancholi, Vania Carmonia-Alcocer, Jennifer A. Evans

Biomedical Sciences Faculty Research and Publications

Circadian rhythms are programmed by the suprachiasmatic nucleus (SCN), which relies on neuropeptide signaling to maintain daily timekeeping. Vasoactive intestinal polypeptide (VIP) is critical for SCN function, but the precise role of VIP neurons in SCN circuits is not fully established. To interrogate their contribution to SCN circuits, VIP neurons can be manipulated specifically using the DNA-editing enzyme Cre recombinase. Although the Cre transgene is assumed to be inert by itself, we find that VIP expression is reduced in both heterozygous and homozygous adult VIP-IRES-Cre mice (JAX 010908). Compared with wild-type mice, homozygous VIP-Cre mice display faster reentrainment and shorter …

The Political Personality Of 2020 Democratic Presidential Nominee Joe Biden, Anne Marie Griebie, Aubrey Immelman

Psychology Faculty Publications

This working paper presents the results of an indirect assessment of the personality of former U.S. vice president Joe Biden, Democratic nominee in the 2020 U.S. presidential election, from the conceptual perspective of personologist Theodore Millon.

Psychodiagnostically relevant data about Biden were collected from biographical sources and media reports and synthesized into a personality profile using the Millon Inventory of Diagnostic Criteria (MIDC), which yields 34 normal and maladaptive personality classifications congruent with DSM-III-R, DSM-IV, and DSM-5.

The personality profile yielded by the MIDC was analyzed on the basis of interpretive guidelines provided in the MIDC and …

Contemplation For Educators: Theoretical, Ethical, And Practical Dimensions Drawn From The Catholic Intellectual Tradition, Joseph Polizzi, Darcy Ronan

Education Faculty Publications

Catholic colleges and universities educate thousands of teachers and school administrators every year to be at the forefront of teaching and leading. The mission and vision of Catholic colleges and universities is unique in higher education while sending their graduates forth into every sector of the wider world. We explore the contribution of the Catholic intellectual tradition (CIT) for colleges of education at Catholic colleges and universities. In this particular piece, we mine the tradition's emphasis on contemplation to cultivate and inform a practice of reflection for aspiring educators.

Clinical Work With Adult Male Incest Survivors: Therapeutic Themes And Perspectives, Kathryn B. Rosenberg

Doctoral Dissertations

For psychotherapists, encountering clients who have experienced sexual trauma or abuse is inevitable, whether or not the abuse is disclosed to the therapist; however, mental health professionals receive extremely limited (if any) training on how to identify or effectively support adult clients who are survivors of childhood sexual abuse (CSA). Many people who experienced CSA, especially those who identify as male, remain isolated and invisible in their suffering as adults even within therapeutic spaces, facing what feel like insurmountable barriers – both internal and external – to getting help. When sexual abuse is intrafamilial, these barriers are both amplified and …

Adaptive Task Sampling For Meta-Learning, Chenghao Liu, Zhihao Wang, Doyen Sahoo, Yuan Fang, Kun Zhang, Steven C. H. Hoi

Research Collection School Of Computing and Information Systems

Meta-learning methods have been extensively studied and applied in computer vision, especially for few-shot classification tasks. The key idea of meta-learning for few-shot classification is to mimic the few-shot situations faced at test time by randomly sampling classes in meta-training data to construct fewshot tasks for episodic training. While a rich line of work focuses solely on how to extract meta-knowledge across tasks, we exploit the complementary problem on how to generate informative tasks. We argue that the randomly sampled tasks could be sub-optimal and uninformative (e.g., the task of classifying “dog” from “laptop” is often trivial) to the meta-learner. …

Sustaining International Trade With China: Does Acfta Improve Asean Export Efficiency?, Antonio Alleyne, Zhaoyong Zhang, Yifei Mu

Research outputs 2014 to 2021

© 2020 by the authors. The business of international trade has never been identified as zero-sum. Yet, dependence on regional agreements to provide alternate means for countries to overlook shortcomings persists. China's recent rise up the trade value-chain has fostered an assumption that the regional agreement provides various advantages to exports from Association of Southeast Asian Nations (ASEAN) member countries. This paper provides an empirical assessment of the ASEAN-China Free Trade Area (ACFTA) impact on ASEAN export efficiency into the Chinese market, in pre and post eras. Using a structured gravity approach to estimate potential export pattern at aggregate and …

Improving Identification Of High-Risk Obstructive Sleep Apnea Patients In Primary Care: An Integrative Review, Lauren Ashley Paulson

Doctoral Dissertations and Projects

Obstructive sleep apnea continues to be an area that is underdiagnosed and therefore undertreated. Left untreated, the condition is associated with increased morbidity and mortality as it can amplify the risk of multiple health conditions. Due to the negative impact of obstructive sleep apnea it is necessary for healthcare providers to provide timely detection. Primary care providers are in a position to identify high-risk individuals and refer them for further follow up testing. High-risk identification can be accomplished by integrating validated screening tools into patient assessments. This integrative review provides an overview of current screening tools for use in the …

The Black Ceiling: The Underrepresentation Of African American Females In The Ces Professorate, Sharon Vanessa Lewis

Doctoral Dissertations and Projects

This qualitative phenomenological study highlighted the lived experiences of six African American female professors in the counseling education and supervision professorate. The professors were faculty within universities across the United States in the mid-Atlantic, southern, and midwestern regions. This study obtained data from semi-structured interviews as well as photovoice submissions from the interview participants in order to identify experiences which facilitated their persistence in the professorate and overcoming internal and external barriers. The research problem was the underrepresentation of African American females within the counseling education and supervision professorate, which further facilitates minority students’ attrition and underrepresentation. A thematic analysis …

The Jewish Origins Of The Ordinances Of Christianity: Worship Within Baptism And The Lord's Supper, John Edward Ross

Doctoral Dissertations and Projects

The modern evangelical denominations have worship services that include many forms of worship and functions to bring the worshiper into communion with the living God as a disciple of Christ. These worship forms include the two ordinances of baptism and the Lord’s Supper. Generations of denominational congregants have participated in these ordinances with little knowledge of the origin of these two rites. This qualitative historical study focuses on the roots of the ordinances of baptism and the Lord’s Supper formed within Christianity during the early church years. Using research from Christian and Messianic Jewish scholars along with Jewish sources, this …

Folk Physics In The Twenty-First Century: Understanding Tooling As Embodied, Dorothy M. Fragaszy, Madhur Mangalam

Journal Articles

Povinelli’s (2000) studies with chimpanzees (Pan troglodytes) reported in “Folk Physics for Apes” were firmly grounded in a Cartesian view of knowledge, which posits that humans use abstract concepts such as force, gravity, and shape to reason causally about events and plan our actions (with tools in the case of Folk Physics for Apes). Povinelli set out to examine if chimpanzees, like humans, used causal concepts to solve mechanical problems, as the Cartesian view predicts. However, Povinelli’s findings uniformly challenged his expectations. Povinelli’s book stimulated research and contributed to the development of alternate understandings of how animals (including humans) use …

Nutraceutical Potential For Alzheimer's Disease Treatment, Alex Gewecke

Undergraduate Research Journal

Alzheimer’s disease (AD) is a progressive disorder involving buildup of excessive amounts of proteins such as beta amyloid in the brain that leads to memory loss, inability to perform daily functions, and an early death. By 2060, the number of cases is forecast to nearly triple current numbers. Age is the primary risk factor for AD and no new drugs have been approved since 2003. Nutraceuticals, a broad category of substances that can be utilized for both medicinal and nutritional purposes may be able to help, which is why they are being more widely researched. Overall, a number of attempts …

Using Speech Screening Process For Preschool-Age Children: Do Results Lead To Action?, Autumn Rhoads

Undergraduate Research Journal

In this paper, we will discuss the concerns of a microstrip two patch antenna system. Coupling of the two-port system can be miniaturized using Electromagnetic Bandgap Structures (EBG) or Defected Ground Structures (DGS) centered between the two patch antennas half a wavelength in size. Different miniaturization methods were used in the design of the antenna system to change the properties of the signal. Changing via locations that are not found on EBG strips themselves, rather found on interleaved ledges between EBG strips allowed for further change in shifting the signals frequency.