Digital Commons Network^™

History Of Northern Mississippi, David Sansing

Studies in English

No abstract provided.

Expression And Localization Of The 14-3-3 (Ywha) Protein Family Within Mammals, Neha Kumrah, Santanu De

Mako: NSU Undergraduate Student Journal

The 14-3-3 (YWHA) are a family of homologous, acidic, and highly conserved proteins expressed abundantly and ubiquitously in a wide array of organisms ranging from plants to animals, including humans, which regulate important cellular events. Within mammals, seven isoforms of 14-3-3 exist: β, γ, ε, ζ, η, τ, and σ (stratifin), each of which is encoded by a unique gene. Studies have shown similar expression patterns among mammalian species. The 14-3-3 proteins are commonly expressed and have proven to play critical roles in proper cellular localization, function, and homeostatic regulation. Numerous researchers have investigated the expression and localization patterns of …

Personalized Medicine: The Use Of Biomarkers And Molecularly Targeted Therapies For Patient Care And Cancer Intervention, Wafa Asad, Emily Schmitt Lavin

Mako: NSU Undergraduate Student Journal

Personalized medicine and targeted therapy have been emerging fields of study for the remediation and inhibition of cancer. Personalized medicine in the treatment of cancer involves using genetic, immune, and proteomic profiling to provide therapeutic options as well as prognostic background for every patient and their tumor’s genetic mutations. Targeted therapies allow researchers and medical personnel alike to determine the appropriate treatment for a patient based on the molecular basis and mechanistic actions of a cancerous tumor. The overall significance of this study was to express how these treatments use biomarkers to pinpoint the location, and severity of the cancer, …

Vol. 13 (1972): Full Issue, Journal Editors

Studies in English

No abstract provided.

The Censors In The Years Of The Calm, Jackson Taylor Jr.

Studies in English

No abstract provided.

Building A Pillar Of Fame, Robert W. Witt

Studies in English

No abstract provided.

Sir Orfeo: The Self And The Nature Of Art, Christina J. Murphy

Studies in English

No abstract provided.

Did You Wash Your Caving Suit? Cavers’ Role In The Potential Spread Of Pseudogymnoascus Destructans, The Causative Agent Of White-Nose Disease, Violeta Zhelyazkova, Antonia Hubancheva, Georgi Radoslavov, Nia Toshkova, Sebastien J. Puechmaille

International Journal of Speleology

White-Nose Disease (WND) has killed millions of hibernating bats in the US and Canada. Its causative agent, the fungus Pseudogymnoascus destructans was introduced to North America, but is native to Europe and Asia, where it is not associated with mass mortality. Although it is nearly impossible to eradicate an emerging wildlife disease, research on P. destructans spread mechanisms can aid in prevention of new introductions and development of better environmental management strategies. It is of particular importance to quantify the potential role of people visiting caves (cavers, tourists, bat researchers, etc.) whom inadvertently move P. destructans spores between sites, and …

The Evolution Of The Rose: From Form To Flame, Kathryn Hart Patton

Studies in English

No abstract provided.

We Are...Marshall, September 9, 2020, Office Of Marshall University Communications

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.

A Novel Mouse Model Expressing Human Forms For Complement Receptors Cr1 And Cr2., Harriet M. Jackson, Kate E Foley, Rita O'Rourke, Timothy M Stearns, Dina Fathalla, B Paul Morgan, Gareth R Howell

Faculty Research 2020

BACKGROUND: The complement cascade is increasingly implicated in development of a variety of diseases with strong immune contributions such as Alzheimer's disease and Systemic Lupus Erythematosus. Mouse models have been used to determine function of central components of the complement cascade such as C1q and C3. However, species differences in their gene structures mean that mice do not adequately replicate human complement regulators, including CR1 and CR2. Genetic variation in CR1 and CR2 have been implicated in modifying disease states but the mechanisms are not known.

RESULTS: To decipher the roles of human CR1 and CR2 in health and disease, …

Covid-19 Brings Campus Changes

St. Norbert Times

News

• COVID-19 Brings Campus Changes
• Remembering George Floyd
• SNC Students March for Veterans
• SNC Launches Respect Initiative
• Norbert’s Ninth Semester
• So Long, Farewell: Commencement 2020

Opinion

• Reading Five Pages A Day
• SNC Parent Facebook Page
• Police Brutality: What Can We Do?
• Dear Everyone

Features

• Behind the Mask: New Staff at SNC
• “CHIP”: An SNC Inspired Novel

Entertainment

• Student Spotlight
• Weeb Corner: “The God of High School”
• Why You Should Watch “Pose”
• Book Review: “Normal People” by Sally Rooney
• Top Three Reads of the Summer
• Coming Soon to Netflix
• Upcoming Events
• Junk Drawer: Favorite Movie Watched During Quarantine

Sports

• CANCELLED: Dan …

The Impact Of Autonomous Vehicles On Urban Land Use Patterns, Gregory M. Stein

Scholarly Works

Autonomous vehicles are coming. The only questions are how quickly they will arrive, how we will manage the years when they share the road with conventional vehicles, and how the legal system will address the issues they raise. This Article examines the impact the autonomous vehicle revolution will have on urban land use patterns.

Autonomous vehicles will transform the use of land and the law governing that valuable land. Automobiles will drop passengers off and then drive themselves to remote parking areas, reducing the need for downtown parking. These vehicles will create the need for substantial changes in roadway design. …

Jeffrey Bletz V. Jeremy Corrie

2020 Decisions

USDC for the Middle District of Pennsylvania

Anti-Trichomonad Activities Of Different Compounds From Foods, Marine Products, And Medicinal Plants: A Review, Mendel Friedman, Christina C. Tam, Luisa W. Cheng, Kirkwood M. Land

College of the Pacific Faculty Articles

Human trichomoniasis, caused by the pathogenic parasitic protozoan Trichomonas vaginalis, is the most common non-viral sexually transmitted disease that contributes to reproductive morbidity in affected women and possibly to prostate cancer in men. Tritrichomonas foetus strains cause the disease trichomoniasis in farm animals (cattle, bulls, pigs) and diarrhea in domestic animals (cats and dogs). Because some T. vaginalis strains have become resistant to the widely used drug metronidazole, there is a need to develop alternative treatments, based on safe natural products that have the potential to replace and/or enhance the activity of lower doses of metronidazole. To help meet this …

Commonwealth Times 2020-09-09

Commonwealth Times, 1969-

No abstract provided.

Covid-19 Update For The University Of Mississippi Community, September 09, 2020, University Of Mississippi

COVID-19 Emails

No abstract provided.

Daily Digest - Wednesday, September 9, 2020 Covid-19 Updates, University Of Mississippi

COVID-19 Website Archives

Campus Update Daily Digest for Wednesday, September 9, 2020

Machine Intelligence For Nerve Conduit Design And Production, Caleb E. Stewart, Chin Fung Kelvin Kan, Brody R. Stewart, Henry W. Sanicola Iii, Jangwook P. Jung, Olawale A. R. Sulaiman, Dadong Wang

Faculty Publications

Nerve guidance conduits (NGCs) have emerged from recent advances within tissue engineering as a promising alternative to autografts for peripheral nerve repair. NGCs are tubular structures with engineered biomaterials, which guide axonal regeneration from the injured proximal nerve to the distal stump. NGC design can synergistically combine multiple properties to enhance proliferation of stem and neuronal cells, improve nerve migration, attenuate inflammation and reduce scar tissue formation. The aim of most laboratories fabricating NGCs is the development of an automated process that incorporates patient-specific features and complex tissue blueprints (e.g. neurovascular conduit) that serve as the basis for more complicated …

Encoding The Odor Of Cigarette Smoke, Timothy S. Mcclintock, Naazneen Khan, Yelena Alimova, Madeline Aulisio, Dong Y. Han, Patrick Breheny

Physiology Faculty Publications

The encoding of odors is believed to begin as a combinatorial code consisting of distinct patterns of responses from odorant receptors (ORs), trace-amine associated receptors (TAARs), or both. To determine how specific response patterns arise requires detecting patterns in vivo and understanding how the components of an odor, which are nearly always mixtures of odorants, give rise to parts of the pattern. Cigarette smoke, a common and clinically relevant odor consisting of > 400 odorants, evokes responses from 144 ORs and 3 TAARs in freely behaving male and female mice, the first example of in vivo responses of both ORs and …

The Lumberjack, September 09, 2020

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.

Smoking And Covid-19: Adding Fuel To The Flame, Vivek K. Kashyap, Anupam Dhasmana, Andrew Massey, Sudhir Kotnala, Nadeem Zafar, Meena Jaggi, Murali M. Yallapu, Subhash C. Chauhan

School of Medicine Publications

The coronavirus disease 2019 (COVID-19) pandemic, an infection caused by the severe acute respiratory syndrome coronavirus (SARS-CoV-2), has led to more than 771,000 deaths worldwide. Tobacco smoking is a major known risk factor for severe illness and even death from many respiratory infections. The effects of smoking on COVID-19 are currently controversial. Here, we provide an overview of the current knowledge on the effects of smoking on the clinical manifestations, disease progression, inflammatory responses, immunopathogenesis, racial ethnic disparities, and incidence of COVID-19. This review also documents future directions of smoking related research in COVID-19. The current epidemiological finding suggests that …

The Impact Of Appendectomy In Clostridium Difficile Infection And Length Of Hospital Stay., Rajesh Essrani Md, Dany Saturno, Shehriyar Mehershahi, Rajesh Kumar Essrani, Muhammad Rajib Hossain, Shri Jai Kirshan Ravi, Andrea Berger, Asif Mehmood

Department of Emergency Medicine

Introduction We aim to investigate Clostridium difficile infection (CDI) recurrence, severity, complications, and length of hospital stay in patients with and without prior history of appendectomy who were admitted to the hospital with CDI. Method We analyzed retrospective data for 862 patients, 18 years and older, with C. difficile inpatients diagnosed between January 1, 2017 and December 31, 2018 and sorted into two groups, with or without prior appendicectomy, to look for outcomes such as recurrence, hospital stay, complications, and related death in each group and use statistical analysis for comparison. Result There were 862 patients admitted with CDI, of …

Astrocytes Deliver Ck1 To Neurons Via Extracellular Vesicles In Response To Inflammation Promoting The Translation And Amyloidogenic Processing Of App, Zhigang Li, Mohammed Moniruzzaman, Raha M. Dastgheyb, Seung-Wan Yoo, Meina Wang, Hongbo Hao, Jia Liu, Patrizia Casaccia, Carlos Nogueras-Ortiz, Dimitrios Kapogiannis, Barbara S. Slusher, Norman J. Haughey

Advanced Science Research Center

Chronic inflammation is thought to contribute to the early pathogenesis of Alzheimer’s disease (AD). However, the precise mechanism by which inflammatory cytokines promote the formation and deposition of Aβ remains unclear. Available data suggest that applications of inflammatory cytokines onto isolated neurons do not promote the formation of Aβ, suggesting an indirect mechanism of action. Based on evidence astrocyte derived extracellular vesicles (astrocyte derived EVs) regulate neuronal functions, and data that inflammatory cytokines can modify the molecular cargo of astrocyte derived EVs, we sought to determine if IL-1β promotes the formation of Aβ indirectly through …

Decentralized Renewable Hybrid Mini-Grids For Rural Communities: Culmination Of The Irep Framework And Scale Up To Urban Communities, Blessing Ugwoke, Adedoyin Adeleke, Stefano P. Corgnati, Joshua M. Pearce, Pierluigi Leone

Michigan Tech Publications, Part 1

The Integrated Rural Energy Planning (IREP) framework offers a unified road map for locating, planning and operating decentralized renewable hybrid off-grid energy systems for localized (rural) applications in low-income countries. This paper presents the culmination of the IREP framework and aims to illustrate the final step of the IREP framework for two communities in Nigeria. It is focused on two aspects. Firstly, the techno-economic modeling (investment and operation optimization) of a hybrid mini-grid system using HOMER Pro, a techno-economic evaluation tool; and evaluating the benefits of demand side management (DSM) based on energy efficiency on the overall system economics using …

Definition And Characteristics Of Behavioral Medicine, And Main Tasks And Goals Of The International Society Of Behavioral Medicine –An International Delphi Study, Joost Dekker, Marie Amitami, Anne H. Berman, Helen Brown, Bryan Cleal, Maria João Figueiras, Lila J. Finney Rutten, Egil A. Fors, Konstadina Griva, Jing Gu, Chris Keyworth, Maria Kleinstäuber, Claas Lahmann, Joseph T. F. Lau, Bernd Leplow

Psychology Faculty Publications

Background: In the past decades, behavioral medicine has attained global recognition. Due to its global reach, a critical need has emerged to consider whether the original definition of behavioral medicine is still valid, comprehensive, and inclusive, and to reconsider the main tasks and goals of the International Society of Behavioral Medicine (ISBM), as the umbrella organization in the field. The purpose of the present study was to (i) update the definition and scope of behavioral medicine and its defining characteristics; and (ii) develop a proposal on ISBM’s main tasks and goals. Method: Our study used the Delphi method. A core …

President's Convocation (2020 Program And Video), Illinois Wesleyan University

President’s Convocation

No abstract provided.

Change Of Regrowth Of Seripidium Transiliensis Poljak In Different Grazing Disturbance, Shazhou An, Zongjiu Sun, Meng Tao, Falan Jin, Xianhua Zhang

IGC Proceedings (1977-2023)

No abstract provided.

Sward Allowance At Early Lactation Of Primiparous Dairy Cows: Iv-Body Condition Score And Reproductive Parameters, M. Lourdes Adrien, A. Meikle, Pablo Soca, D. A. Mattiauda, P. Chilibroste

IGC Proceedings (1977-2023)

No abstract provided.

Effects Of Haloxylon Plantation On Some Soil Characteristics And Vegetation Cover, Mohammad Jafary, H. Niknahad, R. Erfanzadeh, M. Tahmoures

IGC Proceedings (1977-2023)

No abstract provided.