Digital Commons Network^™

Research And Innovation As A Catalyst For Food System Transformation, A.C.L. Den Boer, K.P.W. Kok, M. Gill, J. Breda, Jean Cahill, C. Callenius, P. Caron, Z. Damianova, M. Gurinovic, L. Lahteenmaki, T. Lang, R. Sonnino, G. Verburg, H. Westhoek, T. Cesuroglu, B.J. Regeer, J.E.W. Broerse

Research and Innovation - Other

Background Food systems are associated with severe and persistent problems worldwide. Governance approaches aiming to foster sustainable transformation of food systems face several challenges due to the complex nature of food systems.

Scope and approach In this commentary we argue that addressing these governance challenges requires the development and adoption of novel research and innovation (R&I) approaches that will provide evidence to inform food system transformation and will serve as catalysts for change. We first elaborate on the complexity of food systems (transformation) and stress the need to move beyond traditional linear R&I approaches to be able to respond to …

Research And Innovation Supporting The Farm To Fork Strategy Of The European Commission, R. Sonnino, C. Callenius, L. Lahteenmaki, J. Breda, Jean Cahill, P. Caron, Z. Damianova, M.A. Gurinovic, T. Lang, A. Laperriere, C. Mango, J. Ryder, G. Verbrugh, T. Achterbpscj, A.C.L. Den Boer, K.P.W. Kok, B.J. Regeer, J.E. Broerse, J.E.W. Cesuroglu, T. Gill

Research and Innovation - Other

No abstract provided.

Legitimate Interpretation – Or Legitimate Adjudication?, Thomas W. Merrill

Faculty Scholarship

Current debate about the legitimacy of lawmaking by courts focuses on what constitutes legitimate interpretation. The debate has reached an impasse in that originalism and textualism appear to have the stronger case as a matter of theory while living constitutionalism and dynamic interpretation provide much account of actual practice. This Article argues that if we refocus the debate by asking what constitutes legitimate adjudication, as determined by the social practice of the parties and their lawyers who take part in adjudication, it is possible to develop an account of legitimacy that produces a much better fit between theory and practice. …

Do We Need A New Conception Of Authorship?, Shyamkrishna Balganesh

Faculty Scholarship

Thank you to the organizers for having me. I’m delighted to be here. I’m going to take a step away from conceptual art, and go a little bit into history and a little bit into doctrine – and do the usual law professor thing. We law professors like to say that one of the great things about the job is that we get to overrule the Supreme Court ten thousand times a day, but the bad thing about the job is no one cares. And so, I’m going to try and make this such that you care.

Here’s the core …

Understanding The Comorbidity Of Asthma And Anxiety In Childhood: Characteristics, Vulnerabilities, And Treatment Implications, Nicole Fleischer

PCOM Psychology Dissertations

This study examined potential differences in youth (aged 7-17 years, 76% Caucasian, 52% female) with comorbid asthma and anxiety compared to youth with anxiety without asthma who received cognitive-behavioral therapy (CBT) alone, pharmacotherapy alone, the combination of pharmacotherapy or placebo pill in the Child/Adolescent Multimodal Study. Two groups were compared on negative self-talk; number of physical symptoms; parental anxiety; content of their worries; and presence of panic, generalized anxiety, and separation anxiety disorders across treatment conditions. Findings indicated that youth with asthma and anxiety were more likely to exhibit higher rates of negative self-talk than youth without asthma, possibly related …

An Investigation Into The Prospective Effects Of Vitamin D Supplementation On The Development & Attenuation Of Non-Alcoholic Fatty Liver Disease, Gage Fink

Research Papers

The purpose of this study is to shed light on the potential role of vitamin D in its hydroxylated form, 25-OH-Cholecalciferol(25OHD), in moderating the development and attenuation of non-alcoholic fatty liver disease (NAFLD) via an aged laying hen model. Specifically, thirty-month-old single-comb white Leghorn hens were assigned at random to one of three diets: a control diet (CON) consisting of a standard composition of feed and supplements, a vitamin-D-supplemented group (VID) consisting of the CON diet with an additional 69 μg/kg of 25OHD per day, and a whole flaxseed (WFX) supplemented group used as a comparative intervention standard against the …

Black Action Heroines: From Coffy To Rebel, Morgan Nickles

Research Papers

No abstract provided.

Evaluation Of The Csr1-2 Allele From Arabidopsis Thaliana Cs3102 As An Imazapyr Herbicide Resistance Marker For Biolistic Transformation Of The Shoot Apical Meristem, Amanda J. Stump

Dissertations and Theses @ UNI

Plant genetic engineering requires a marker gene to differentiate transformed cells. To test the csr1-2 allele as a selectable marker for the shoot apical meristem (SAM), we cloned a genomic fragment from Arabidopsis thaliana mutant CS3102 which contained the coding sequence and promoter. We then evaluated the utility of this allele on two model systems, Arabidopsis and tobacco, with soybean as the positive control. Initial dose-response experiments were conducted using a seedling plate assay to determine the lethal dose of imazapyr. For the mutant Arabidopsis thaliana CS3102, a concentration of 500 μM imazapyr was required to overcome the resistance phenotype …

Recoverability Of Large Vs Small Muscle Groups, Jacob Alan Clark

Dissertations and Theses @ UNI

The purpose of this study was to assess differences in recovery between muscles with larger cross-sectional area (Quadriceps) compared to muscles with smaller cross-sectional area (Biceps). Recreationally trained male weight lifters aged 18-30 (n = 9) volunteered in this muscle recovery study. All participants were asked to attend two testing sessions in addition to an initial meeting, all of which took no more than 45-mintues per session to complete. After this initial session where the 10 RM in the biceps curl and quadricep extension were determined, participants were scheduled to perform the biceps curl and quad extension for four sets …

A Ground Based Investigation Of Snow Metamorphism Using An Energy Flux Model And Hyperspectral Imaging Across Cropland, Grassland And Barren Surface In Northeast Iowa, Ayan Sasmal

Dissertations and Theses @ UNI

Snow is unstable under natural environmental conditions; it undergoes metamorphism that can be measurable with an energy flux model. The demand for snow research is increasing due to its importance for maintaining Earth’s energy balance and hydrological applications. Snow metamorphism is a process of transformation of snow particles with an expense of surface free energy. Very few studies have been completed on snow metamorphism in grassland, cropland and barren surfaces that needs farther investigation. In this study, an attempt was made to measure winter snow metamorphism with physical based model and detecting snow metamorphism by using hyperspectral imaging spectroradiameter in …

"This Is How We Play Destroy": Deconstruction And The Construction Of A Cyborg Future In Poppy's Am I A Girl?, Stevie Eve Sanchez

Dissertations and Theses @ UNI

Internet sensation and pop music star Poppy’s 2018 sophomore album Am I a Girl? stands out in an increasingly oversaturated pop landscape, thanks to evocative imagery, cleverly ambiguous lyrics, and daring genre crossovers that challenge conventions of contemporarypop music. Despite the album’s titular question, Poppy is not interested in being defined—instead, she seeks to transcend definition and exist in the space of questioning.On the album, Poppy explores concepts like gender, class, and consciousness in a way that pushes the boundaries of pop, deconstructing her genre, while also deconstructing the issues she sings about—and offering a vision for a future that …

2020 Program, University Of Missouri-St. Louis

Undergraduate Research Symposium

University of Missouri-St. Louis Undergraduate Research Symposium Program

Reducing Meat Consumption: Drawing On Participatory Action Research To Explore Ways Of Engaging In A Process Of Meat Consumption Reduction, Brittany Spadafore

Theses and Dissertations (Comprehensive)

With growing attention to climate change and human impacts on the environment, an emerging body of literature is exploring the impacts of global reliance on meat consumption. Research is increasingly supporting the feasibility of reducing meat consumption to address the environmental pressures of the global food system. However, recommended strategies to promote a reduction in meat consumption have been limited due to narrowly focusing on individual rational decision-making models. Centralizing a Social Practice theoretical lens, the present study utilized an approach to participatory action research to explore the experiences of seven (N = 7) green-building tenants reducing their meat consumption …

Risk Factors Related To School Shootings, Best Anaele

Theses and Dissertations (Comprehensive)

School shootings have become a major issue in the United States for over the past 20 years, contributing to the resurgence of the debates surrounding gun control policies. However, further research is needed to better understand the risk factors of school shootings. The FBI constructed the Four-Pronged Threat Assessment Model, a risk assessment specifically applied to school shooters (O’Toole, n.d). Within the current study, the Four-Pronged Threat Assessment Model will be applied to five school shooters: Eric Harris, Dylan Klebold (both Columbine school shooters), Seung Heung Cho (the Virginia Tech School Shooter), Adam Lanza (the Sandy Hook School Shooter), and …

Examining The Longer-Term Impact Of A Home-Visiting Intervention Program On The School Readiness Skills Of English Language Learners In Kindergarten, Michelle Mccann

Theses and Dissertations (Comprehensive)

Young English Language Learners (ELL) present with varied profiles in their language and literacy development with parental involvement promoting development. The Home Instruction for Parents and Preschool Youngsters Program (HIPPY) is a free home-visiting intervention designed to empower parents to be their child’s first teacher. The current study examined the effectiveness of the HIPPY program on language, reading, and social/emotional skills of kindergarten aged ELLs. The HIPPY group was compared to an English as a first language group (EL1) and a control group of ELL students who did not participate in HIPPY (ESL). Participants were assessed at two time points, …

Synthesis And Biophysical Analysis Of The Cell-Penetrating Peptide Penetratin And Its Aromatic Analogues, An Le

Theses and Dissertations (Comprehensive)

Cell-penetrating peptides (CPPs) interact with biological membranes, undergo cellular intake/uptake, and may act as potential drug delivery agents. Understanding the molecular interactions of these peptides with membranes contributes to gaining a better knowledge of their potential use in medical and pharmaceutical applications to improve human health. The current research focuses on understanding the mechanisms of a CPP in interaction with different model phospholipid membranes. The peptide penetratin (primary sequence: RQIKIWFQNRRMKWKK) is an example of a CPP that can interact with and pass through biological membranes. The current thesis provides spectroscopic and calorimetric evidence that penetratin associates with lipid membranes. Circular …

Investigating Diel, Seasonal, And Interannual Variability Of Dissolved And Particulate Stable Carbon Isotope Values In A Eutrophic Boreal Lake, Rachel Henderson

Theses and Dissertations (Comprehensive)

Lakes are globally significant sources, sinks, and conduits of carbon. Cultural eutrophication of freshwater promotes the growth of phytoplankton blooms, which can transform, respire, and sequester large amounts of carbon. Analysis of stable carbon isotopes is a common tool to study the movement of carbon through the aquatic carbon cycle. The causes of temporal variability in δ¹³C values at different timescales are not well understood, and differ between lakes. In this study, I investigated diel, seasonal, and interannual variability in δ¹³C values of dissolved inorganic carbon (DIC) and particulate organic carbon (POC) in Lake 227, an …

Images Of Ancient Egypt And The Gender Politics Of The Faerie Queene, Genavieve Alt

College of Graduate Studies: Theses & Dissertations

My thesis argues that Edmund Spenser uses radically different representations of Ancient Egypt to explore complex ideas about gender roles in the Faerie Queene. Book III emphasizes the negative view of Egypt perpetuated through the Book of Exodus and Greek understanding of the mythological king Busiris. Book V emphasizes the positive view of Egypt through the many benevolent myths surrounding the goddess Isis. Spenser uses images of good and evil Egypt to discuss the abolition of normative gender roles.

The introductory section will introduce the mythology surrounding Isis followed by a discussion of the literature referenced throughout. The first …

Comprehensive Study Of Bio-Diesel Continuous Flow Synthesis, Aso A. Hassan

Doctoral Dissertations

“Energy has become an indispensable factor in preserving economic growth since the commencement of the industrial revolution. In recent years, biodiesel has gained acceptance as a notable alternative to the widely used petroleum-derived diesel fuel because it is biodegradable, non-toxic, and generates fewer exhaust pollutants. Recently, biodiesel studies have focused on the development of process intensification technologies to resolve some technical challenges facing biodiesel production, such as long residence times and catalyst sensitivity. These intensification technologies enhance process mass/heat transfer to achieve a continuous, scalable process that can be easily transported to utilize locally available feed stocks. Five phases have …

Hydrokinetic Turbine Composite Blades And Sandwich Structures: Damage Evaluation And Numerical Simulation, Mokhtar Fal

Doctoral Dissertations

“Composite materials are gaining interest due to their high strength to weight ratio. This study deals with both experimental and numerical approaches to cover the aspects of the failure of composite materials in hydrokinetic turbine applications. In Part I, the location and magnitude of failure in the horizontal axis water turbine carbon fiber-reinforced polymer (CFRP) composite blades with different laminate stacking sequences were investigated. Two lay-up orientations were adopted for this work ([0⁰]₄ and [0⁰/90⁰]_2s). A finite element analysis model was generated to examine the stresses along the blade. Five angles were introduced to study the effect …

Building Renewed Relevance: Portraits Of Ceos Rebranding Iconic Nonprofit Organizations, Helen A. Lowman

Antioch University Dissertations & Theses

In the United States, we often refer to the social sector as one leg of a three-legged stool. The private and public sectors support the other two legs. The social sector made up of nonprofit, nongovernmental, and charity organizations, contributes to the development of American society by focusing on social good rather than the desire to make profit. For decades, the sector has functioned as the social conscience of our society. However, many iconic, legacy nonprofits have struggled to keep their relevance in today’s world: their creation tied to a past societal problem, their mission and brand no longer germane …

Generative Leadership And The Life Of Aurelia Erskine Brazeal, A Trailblazing African American Female Foreign Service Officer, Atim Eneida George

Antioch University Dissertations & Theses

There is a gap in the literature on generativity and the leadership philosophy and praxis of African American Female Foreign Service Officers (AAFFSOs). I addressed this deficit, in part, by engaging an individual of exceptional merit and distinction—Aurelia Erskine Brazeal—as an exemplar of AAFFSOs. Using qualitative research methods of portraiture and oral history, supplemented by collage, mind mapping and word clouds, this study examined Brazeal’s formative years in the segregated South and the extraordinary steps her parents took to protect her from the toxic effects of racism and legal segregation. In addition, I explored the development of Brazeal’s interest in …

A Case Study: The Role Of Compassionate Cities, Healthy Cities, And Un Sustainable Development Goals In City Leadership And Planning, Lisa A. Berkley

Antioch University Dissertations & Theses

This research is a case study examining the relevance of three holistic city frameworks—Compassionate Cities, Healthy Cities, and UN Sustainable Development Goals—to the intentional or tacit thinking of city leaders, community leaders, and activists of Marina, California. Beginning with a discussion of the origin and development of the three frameworks, the study occurred in three phases: Phase I involved interviewing the five elected leaders, city manager, community development leaders, and two planners; Phase II consisted of a survey of appointed city leaders and community organizers and activists; and Phase III was an analysis of relevant public discourse, drawing from local …

Ethical Leadership: Life Story Of George Ciampa, U.S. Wwii Military Veteran And Community Leader, Susan M. Wiedemann

Antioch University Dissertations & Theses

This qualitative research study explored the influence of life experiences and personal ethics of George Ciampa, a United States military veteran; his work in establishing American military cemeteries in Europe; and later work as a community leader committed to teaching American youth about the cost of freedom. Dimensions of ethical leadership and public service motivation served as the theoretical framework for the study. The research extended knowledge on ethical constructs within the fields of leadership studies and public administration; recorded personal experiences that were absent in military historical archives; and increased awareness of aspects of the U.S. military subculture. The …

Social-Emotional Climate In The Community College Classroom: An Action Research Study Investigating The Impact Of Real-Time Student Feedback To Instructors, Angela E. Quitadamo

Antioch University Dissertations & Theses

Community college students often have obligations outside the classroom (supporting dependents or working part-or full-time jobs), preventing them from participating in extracurricular activities and fulfilling their social-emotional needs on campus. As a result, they rely heavily on classroom interactions with their instructors to gain a sense of belonging and motivation necessary for optimal cognitive growth. This action research study was conducted at a rural community college in New England to learn if an informal feedback tool, given to students, could provide real-time data to instructors to enhance the social-emotional classroom environment. An inquiry group (IG) comprised of the researcher and …

In Pictures And Words: A Womanist Answer To Addressing The Lived Experience Of African American Women And Their Bodies—A Gumbo Of Liberation And Healing, Yolandé Aileen Ifalami Devoe

Antioch University Dissertations & Theses

Whether it is claiming a radical self-love for one’s body or dissatisfaction of one’s body, the experiences of African American women and their bodies cannot be divergent from the sociocultural contexts in which they live. Seeking to reveal how gender, race, and sexual orientation impact the lived experiences of African American women and their bodies, this study will bring attention to and provide a more nuanced understanding of the historical and sociocultural ramifications of the Black female body. Historically, inadequate attention has been given to an intersectional approach to understanding the experiences of the Black female body. It is understood …

Understanding The Context And Social Processes That Shape Person- And Family-Centered Culture In Long-Term Care: The Pivotal Role Of Personal Support Workers, Ellen Helena Melis

Antioch University Dissertations & Theses

This single, exemplar case study explored the context and social processes that shape person-and family-centered culture in a long-term care (LTC) home, using grounded theory and situational analysis for the data collection and analysis. Findings revealed one core dimension: needing to be heard, valued, and understood, and five key roles: personal support workers (PSWs), executive director (ED), senior leadership, nurse managers, and residents and families, which informed five dimensions, each focused on enhancing care for residents: (a) attending to residents’ daily care needs (PSWs), (b) advocating strategically (ED), (c) translating vision into programs and policies (senior leadership), (d) ensuring quality …

Bioactive Indanes: Development And Validation Of An Lc-Ms/Ms Bioanalytical Method For The Determination Of Ph46a, A New Potential Anti-Inflammatory Agent, In Dog And Rat Plasma And Its Application To A Pharmacokinetic Study In Dog, Gaia Scalabrino, Tao Zhang, Neil Frankish, Helen Sheridan

Articles

A new chemical entity, which is a chiral indane dimer, PH46A, has been developed by our research group. As a clinical candidate. PH46A has recently completed Phase I clinical studies in man. Previously, during its pre-clinical development, in in vivo pre-clinical studies PH46A showed potent anti-inflammatory properties, which can be targeted at a range of diseases, including inflammatory bowel disease (IBD). To support the pre-clinical development of this drug candidate, we developed a LC MS/MS method for determining PH46 (the acid form of PH46A salt) in both dog and rat plasma using Compound 1 as internal standard (IS). Those species …

Novel Mast Cell-Stabilising Amine Derivatives Of 3,4 Dihydronaphthalen-1(2h)-One And 6,7,8,9-Tetrahydro-5h-Benzo[7]Annulen-5-One, James W. Barlow, Tao Zhang, Orla Woods, Adam J. Byrne, John J. Walsh

Articles

In an investigation of 4-amino-3,4-dihydronaphthalen-1(2H)-ones as novel modulators of allergic and inflammatory phenomena, we have investigated a series of cyclic analogues. Tertiary amines of structural types 9, 10, 20 and 21 were synthesised and evaluated for mast cell stabilising activity. In vitro and in vivo studies showed that of these compounds, the cyclohexenylamino derivatives of tetralone and benzosuberone of series 20 and 21 exhibited interesting activity both in vitro and in vivo.

Mast Cell Stabilisers, Tao Zhang, Deirdre Frances Finn, James William Barlow, John Jarlath Walsh

Articles

Mast cells play a critical role in type 1 hypersensitivity reactions. Indeed, mast cell mediators are implicated in many different conditions including allergic rhinitis, conjunctivitis, asthma, psoriasis, mastocytosis and the progression of many different cancers. Thus, there is intense interest in the development of agents which prevent mast cell mediator release or which inhibit the actions of such mediators once released into the environment of the cell. Much progress into the design of new agents has been made since the initial discovery of the mast cell stabilising properties of khellin from Ammi visnaga and the clinical approval of cromolyn sodium. …