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2020

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Articles 23131 - 23160 of 24013

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Protective Effects Of Apocynin On Damaged Testes Of Rats Exposed To Methotrexate, Kübra Kavram Sarihan, Melda Yardimoğlu Yilmaz, Fatma Ceyla Eraldemi̇r, Yusufhan Yazir, Esra Acar Jan 2020

Protective Effects Of Apocynin On Damaged Testes Of Rats Exposed To Methotrexate, Kübra Kavram Sarihan, Melda Yardimoğlu Yilmaz, Fatma Ceyla Eraldemi̇r, Yusufhan Yazir, Esra Acar

Turkish Journal of Medical Sciences

Background/aim: Methotrexate (MTX), widely used as a drug in cancer, has many adverse effects on tissues. Apocynin (APO) is a NADPH oxidase inhibitor and is known with many antioxidant properties. In this study, we aimed to evaluate the adverse effects of MTX on testicular tissue and the protective effects of APO at two different doses (20 mg/kg and 50 mg/kg) on MTX-induced testicular damage.Materials and methods: Fifty adult male Wistar albino rats (8 weeks old and weighing 200-250 g) were divided into five groups of 10 rats each: 1. saline control, 2. dimethyl sulfoxide (DMSO) control, 3. MTX, 4. APO-20 …

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Melatonin Attenuates Ovarian Ischemia Reperfusion Injury In Rats By Decreasing Oxidative Stress Index And Peroxynitrite, Şenol Kalyoncu, Bülent Yilmaz, Mustafa Demi̇r, Meltem Tuncer, Zehra Bozdağ, Onur Ince, Mehmet Aki̇f Bozdayi, Hasan Ulusal, Seyi̇than Taysi Jan 2020

Melatonin Attenuates Ovarian Ischemia Reperfusion Injury In Rats By Decreasing Oxidative Stress Index And Peroxynitrite, Şenol Kalyoncu, Bülent Yilmaz, Mustafa Demi̇r, Meltem Tuncer, Zehra Bozdağ, Onur Ince, Mehmet Aki̇f Bozdayi, Hasan Ulusal, Seyi̇than Taysi

Turkish Journal of Medical Sciences

Background/aim: To evaluate the protective effect of melatonin on ovarian ischemia reperfusion injury in a rat model. Materials and methods: Forty-eight rats were separated equally into 6 groups. Group 1: sham; Group 2: surgical control with 3-h bilateral ovarian torsion and detorsion; Group 3: intraperitoneal 5% ethanol (1 mL) just after detorsion (as melatonin was dissolved in ethanol); Group 4: 10 mg/kg intraperitoneal melatonin 30 min before 3-h torsion; Group 5:10 mg/kg intraperitoneal melatonin just after detorsion; Group 6:10 mg/kg intraperitoneal melatonin 30 min before torsion and just after detorsion. Both ovaries and blood samples were obtained 7 days after …

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Neuropeptide Y1 Receptor Antagonist But Not Neuropeptide Y Itself Increased Bone Mineral Density When Locally Injected With Hyaluronic Acid In Male Wistar Rats, Muhammer Özgür Çevi̇k, Petek Korkusuz, Feza Korkusuz Jan 2020

Neuropeptide Y1 Receptor Antagonist But Not Neuropeptide Y Itself Increased Bone Mineral Density When Locally Injected With Hyaluronic Acid In Male Wistar Rats, Muhammer Özgür Çevi̇k, Petek Korkusuz, Feza Korkusuz

Turkish Journal of Medical Sciences

Background/aim: The nervous system controls bone mass via both the central (CNS) and the peripheral (PNS) nervous systems. Intriguingly, neuropeptide Y (NPY) signaling occurs in both. Less is known on how the PNS stimulated NPY signaling controls bone metabolism. The objective of this study was to evaluate whether NPY or NPY1 receptor antagonist changes local bone mineral density (BMD) when injected into a Wistar rat tibia. Materials and methods: Tibial intramedullary area of 24 wild type male Wistar rats (average weight = 350 ± 50 g, average age = 4 ± 0.5 months) were injected with NPY (1 × 10-5 …

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Urinay Neutrophil Gelatinase-Associated Lipocalin As A Biomarker In Different Renal Problems, Di̇dem Turgut, Serhan Vahi̇t Pi̇şki̇npaşa, Ezgi̇ Çoşkun Yeni̇gün, Ni̇hal Aydemi̇r, Fati̇h Dede Jan 2020

Urinay Neutrophil Gelatinase-Associated Lipocalin As A Biomarker In Different Renal Problems, Di̇dem Turgut, Serhan Vahi̇t Pi̇şki̇npaşa, Ezgi̇ Çoşkun Yeni̇gün, Ni̇hal Aydemi̇r, Fati̇h Dede

Turkish Journal of Medical Sciences

Background/aim: Neutrophil gelatinase-associated lipocalin (NGAL) is used previously to estimate the etiology, severity, and clinical outcomes of acute kidney injury (AKI). However, the role of urinary NGAL (uNGAL) in the postrenal setting is not clear. In our study, we aimed to discover the cut-off value of uNGAL that can be used in the differential diagnosis of underlying AKI etiologies. Materials and methods: In this prospective cross-sectional study, we examined 82 subjects in four groups: patients that had (1) postrenal AKI; (2) AKI other than postrenal etiologies; (3) stable chronic kidney disease; and (4) healthy subjects. A renal function assessment was …

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The Assessment Of The Serum Levels Of Tweak And Prostaglandin F2∝ In Covid - 19, Demet Yalçin Kehri̇bar, Mustafa Ci̇hangi̇roğlu, Emi̇ne Sehmen, Bahatti̇n Avci, Mustafa Çapraz, Maruf Boran, Caner Günaydin, Meti̇n Özgen Jan 2020

The Assessment Of The Serum Levels Of Tweak And Prostaglandin F2∝ In Covid - 19, Demet Yalçin Kehri̇bar, Mustafa Ci̇hangi̇roğlu, Emi̇ne Sehmen, Bahatti̇n Avci, Mustafa Çapraz, Maruf Boran, Caner Günaydin, Meti̇n Özgen

Turkish Journal of Medical Sciences

Background/aim: It is claimed that aberrant immune response has a more important role than the cytopathic effect of the virus in the morbidity and mortality of the coronavirus disease 2019 (COVID-19). We aimed to investigate the possible roles of tumor necrosis factor-like weak inducer of apoptosis (TWEAK)/Fn14 pathway and leukotrienes (LT) in uncontrolled immune response that occurs in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Materials and methods: This study included 25 asymptomatic patients and 35 patients with lung involvement who were diagnosed with COVID-19 as well as 22 healthy volunteers. Lung involvement was determined using computed-tomography. Serum TWEAK, LTE4, …

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Comparison Of Ischemic Preconditioning And Botulinuma Toxin Injection For The Prevention Of Ischemia-Reperfusion Injury In Musculocutaneous Flaps, Handan Derebaşinlioğlu, Anil Demi̇röz, Yağmur Aydin, Hakan Ekmekçi̇, Özlem Balci Ekmekçi̇, Övgü Aydin, Levent Cankorkmaz Jan 2020

Comparison Of Ischemic Preconditioning And Botulinuma Toxin Injection For The Prevention Of Ischemia-Reperfusion Injury In Musculocutaneous Flaps, Handan Derebaşinlioğlu, Anil Demi̇röz, Yağmur Aydin, Hakan Ekmekçi̇, Özlem Balci Ekmekçi̇, Övgü Aydin, Levent Cankorkmaz

Turkish Journal of Medical Sciences

Background/aim: The aim of the study was to evaluate the protective effect of Botulinum A toxin injection against ischemia-reperfusion injury. Materials and methods: Thirty-two Sprague-Dawley rats were divided into: control, ischemia-reperfusion, ischemic preconditioning, and botulinum groups. In all groups the musculocutaneous pedicle flap was occluded for 4 h, and then reperfused to induce ischemia- reperfusion injury. Serum and tissue myeloperoxidase (MPO) and nitric oxide (NO) levels were measured at 24 h and at 10 days. Results: Tissue MPO levels did not differ significantly between the ischemic preconditioning and botulinum groups at 24 h but was significantly lower in the botulinum …

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Influence Of Aluminum Salts On Covid-19 Infected Patients, Ali̇ Demi̇r, İbrahi̇m Erayman, Oğuz Doğan, Murat Keki̇lli̇ Jan 2020

Influence Of Aluminum Salts On Covid-19 Infected Patients, Ali̇ Demi̇r, İbrahi̇m Erayman, Oğuz Doğan, Murat Keki̇lli̇

Turkish Journal of Medical Sciences

Background/aim: Based on the antiviral and antibacterial properties of aluminum salts, we aimed to find out the influence of aluminum salts on COVID-19 infected patients. Materials and methods: We performed an observational retrospective cohort study which includes the patients diagnosed as COVID-19 and received aluminum salts in addition to actual treatments during hospitalization as the treatment group (Alum Group). Patients who received standard COVID-19 treatment protocols in the Infectious Diseases Clinics were included as the Control Group. Clinical findings, laboratory parameters, length of stay, survival, radiological follow-up, intensive care and mechanical ventilation needs, the presence of comorbidity, polymerase chain reaction …

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Serum Paraoxonase 1 And 3 Activities In Benign And Malignant Diseases Of The Prostateand Changes In Levels Following Robotic-Assisted Laparoscopic Radical Prostatectomy, Fevzi̇ Bedi̇r, Hüseyi̇n Kocatürk, Mehmet Sefa Altay, Engi̇n Şebi̇n, Banu Bedi̇r Jan 2020

Serum Paraoxonase 1 And 3 Activities In Benign And Malignant Diseases Of The Prostateand Changes In Levels Following Robotic-Assisted Laparoscopic Radical Prostatectomy, Fevzi̇ Bedi̇r, Hüseyi̇n Kocatürk, Mehmet Sefa Altay, Engi̇n Şebi̇n, Banu Bedi̇r

Turkish Journal of Medical Sciences

Background/aim: This study aimed to examine serum paraoxonase 1 and 3 (PON1 and PON3) activities in benign and malignant diseases of the prostate, to determine lipid profile and malondialdehyde (MDA) levels, and to investigate changes in levels following robotic-assisted laparoscopic radical prostatectomy (RALRP). Materials and methods: A total of 137 patients, including a control group, were enrolled in the study and assigned into four groups. Group 1 (n = 33) consisted of patients previously undergoing RALRP with no recurrence, group 2 (n = 36) consisted of patients diagnosed with prostate cancer (PCa) and undergoing RALRP, and group 3 (n = …

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Genetic Evaluation Of Mycobacterium Bovis Isolates With Miru-Vntr And Spoligotyping, Nevi̇n Tuzcu, Fati̇h Köksal Jan 2020

Genetic Evaluation Of Mycobacterium Bovis Isolates With Miru-Vntr And Spoligotyping, Nevi̇n Tuzcu, Fati̇h Köksal

Turkish Journal of Medical Sciences

Background/aim: Determining the epidemiological characteristics of M. bovis strains isolated from human and animal tuberculosis cases will assist in taking more appropriate and effective control measures in controlling tuberculosis originating from animals. Materials and methods: In this study, 32 M. bovis isolates of animal origin and 10 of human origin were isolated and identified in the Çukurova region between March 2011 and June 2012. The 12-locus MIRU-VNTR and spoligotyping methods were used. Results: Six different patterns were determined by spoligotyping and 10 by MIRU-VNTR. When both methods were used together, the number of patterns was found to be 28; MIRU4, …

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Iron Homeostasis Is Altered In Response To Hypoxia And Hypothermic Preconditioning Inbrain Glial Cells, Lati̇fe Arzu Aral, Mehmet Ali̇ Ergün, Ayşe Başak Engi̇n, Alp Özgün Börcek, Hayrunni̇sa Bolay Belen Jan 2020

Iron Homeostasis Is Altered In Response To Hypoxia And Hypothermic Preconditioning Inbrain Glial Cells, Lati̇fe Arzu Aral, Mehmet Ali̇ Ergün, Ayşe Başak Engi̇n, Alp Özgün Börcek, Hayrunni̇sa Bolay Belen

Turkish Journal of Medical Sciences

Background/aim: Altered iron metabolism is one of the pathophysiological mechanisms occurring during hypoxic injuries in the central nervous system. Proper homeostasis of cellular iron is regulated by iron import, storage, and export proteins that prevent excess iron overload or iron starvation in cells. Therapeutic hypothermia is an approved treatment for hypoxic ischemia in newborns, but the underlying molecular mechanism is still unknown. We studied the effects of hypoxia, preceded with preconditioning, on the iron homeostasis of glial cells, known as a major actor in the inflammatory process during perinatal brain injury. Materials and methods: Primary microglia and astrocytes in culture …

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Antioxidative Effects Of Uridine In A Neonatal Rat Model Of Hyperoxic Brain Injury, Nevi̇n Al, Ayşen Çakir, Cansu Sevi̇nç, Mehmet Cansev, Tüli̇n Alkan Jan 2020

Antioxidative Effects Of Uridine In A Neonatal Rat Model Of Hyperoxic Brain Injury, Nevi̇n Al, Ayşen Çakir, Cansu Sevi̇nç, Mehmet Cansev, Tüli̇n Alkan

Turkish Journal of Medical Sciences

Background/aim: Premature birth is a major problem that results in an increased risk of mortality and morbidity. The management of such infants consists of supraphysiological oxygen therapy, which affects brain development due, in part, to the deterioration caused by reactive oxygen species (ROS). We showed previously that exogenously administered uridine provides neuroprotection in a neonatal rat model of hyperoxic brain injury. Hence, the aim of the present study was to investigate the effects of uridine on ROS in the same setting. Materials and methods: Hyperoxic brain injury was induced by subjecting a total of 53 six-day-old rat pups to 80% …

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Peripheral Axonal Excitability In Hemiplegia Related To Subacute Stroke, Zeynep Turan, Murat Zi̇nnuroğlu Jan 2020

Peripheral Axonal Excitability In Hemiplegia Related To Subacute Stroke, Zeynep Turan, Murat Zi̇nnuroğlu

Turkish Journal of Medical Sciences

Background/aim: This study aims to investigate peripheral nerve excitability in patients with subacute stroke. Materials and methods: The study was performed in 29 stroke patients within the subacute period and 29 healthy controls using QTRAC software and TRONDNF protocol. The threshold electrotonus, recovery cycle, stimulus-response, strength-duration, and current-threshold relationships were recorded. Results: The membrane was more hyperpolarized, and excitability was decreased in the hemiplegic side. The impairment of inward rectifying channel function, degree of hyperpolarization, and decrease of excitability were directly related to the Brunnstrom stages, which were more pronounced in lower stages. Conclusion: The lower motor neurons were affected …

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Research On The Protective Effect Of Caffeic Acid Phenethyl Ester On Testicular Damagecaused By Cisplatin, Tayfun Ceylan, Emi̇n Kaymak, Fazi̇le Cantürk Tan, Bi̇rkan Yakan Jan 2020

Research On The Protective Effect Of Caffeic Acid Phenethyl Ester On Testicular Damagecaused By Cisplatin, Tayfun Ceylan, Emi̇n Kaymak, Fazi̇le Cantürk Tan, Bi̇rkan Yakan

Turkish Journal of Medical Sciences

Background/aim: Cisplatin (CP), a chemotherapeutic drug, causes damage to spermatogenic serial cells, Sertoli cells, and Leydig cells in rat testicles. It was aimed to investigate the protective effect of caffeic acid phenethyl ester (CAPE), one of the active ingredients of propolis, in eliminating CP-induced testicular damage. Materials and methods: Group 1 (control group) was given physiological saline solution intraperitoneally (IP) throughout the experiment. Group 2 (CP group) was given a single dose of CP (7 mg/kg) IP on the day 7. Group 3 (CP + CAPE group), was given CAPE (10 μmol/kg/day) IP for 12 days and a single dose …

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Mango Ginger (Curcuma Amada) Inhibits Collagen-Induced Arthritis By Modulatinginflammatory Cytokine Levels In Rats, Ahmet Karataş, Cemal Orhan, Mehmet Tuzcu, Nurhan Şahi̇n, İbrahi̇m Hani̇fi̇ Özercan, Süleyman Serdar Koca, Vijaya Juturu, Kazi̇m Şahi̇n Jan 2020

Mango Ginger (Curcuma Amada) Inhibits Collagen-Induced Arthritis By Modulatinginflammatory Cytokine Levels In Rats, Ahmet Karataş, Cemal Orhan, Mehmet Tuzcu, Nurhan Şahi̇n, İbrahi̇m Hani̇fi̇ Özercan, Süleyman Serdar Koca, Vijaya Juturu, Kazi̇m Şahi̇n

Turkish Journal of Medical Sciences

Background/aim: Mango ginger (MG: curcuma amada) has antioxidant and antiinflammatory activities. The aim was to evaluate the antiarthritic potential efficacy of MG on collagen-induced arthritis. Materials and methods: Twenty-one female Wistar-albino rats were divided into three groups. Arthritis was induced by intradermal injections of type II collagen and Freund's adjuvant. MG extract was orally administered starting from the first collagen injection. TNF-α, IL-6, IL-17, obestatin, sclerostin, and DKK-1 serum levels were determined, and perisynovial inflammation and cartilage-bone destruction in the paws were histologically evaluated. Moreover, joint tissue TNF-α, IL-17, NF-κB, and COX-2 levels were analyzed. Results: TNF-α, IL-17, IL-6, and …

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Protective Measures For Covid-19 For Healthcare Providers And Laboratory Personnel, Canan Ağalar, Derya Öztürk Engi̇n Jan 2020

Protective Measures For Covid-19 For Healthcare Providers And Laboratory Personnel, Canan Ağalar, Derya Öztürk Engi̇n

Turkish Journal of Medical Sciences

In the COVID-19 pandemic, which affects the whole world, healthcare professionals (HCP) are at high risk of transmission due to their direct contact with patients with COVID-19. Therefore, how to ensure the triage of the patient with acute respiratory symptoms should be determined in advance, the contact distance should be arranged to be at least 2 m, COVID-19 suspect or diagnosed patient should be instructed to wear a surgical mask. During the care of these patients, HCP should wear their personal protective equipment (PPE) in accordance with the procedure and should not neglect hand hygiene. The samples of the patient …

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Understanding Dynamics Of Pandemics, Levent Akin, Mustafa Gökhan Gözel Jan 2020

Understanding Dynamics Of Pandemics, Levent Akin, Mustafa Gökhan Gözel

Turkish Journal of Medical Sciences

Along the centuries, novel strain of virus such as influenza produces pandemics which increase illness, death and disruption in the countries. Spanish flu in 1918, Asian flu in 1957, Hong Kong flu in 1968 and swine flu in 2009 were known pandemic which had various characteristics in terms of morbidity and mortality. A current pandemic is caused by novel corona virus originated from China. COVID-19 pandemic is very similar to Spanish, Hong Kong, Asian and swine influenza pandemics in terms of spreading to world by the mobilized people. Burden of pandemic is considered in terms of disease transmissibility and the …

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Global Surveillance, Travel, And Trade During A Pandemic, Ceren Çeti̇n, Ateş Kara Jan 2020

Global Surveillance, Travel, And Trade During A Pandemic, Ceren Çeti̇n, Ateş Kara

Turkish Journal of Medical Sciences

Pandemics have had very important consequences in human history. Lots of people lost their lives and countries have been intensively affected in terms of socioeconomic problems. Unfortunately, avoidance of pandemics and limiting the spread are still currently not always possible. Maybe the most important factor for this is the increasing frequency of traveling. Increasing airline traveling rate also increases the rate of spread. Global organizations like the World Health Organization and United Nations are trying to play a supreme role over the countries. Pandemics do not have borders; therefore, efforts should be given globally, definition of pandemic should be established …

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Coronaviruses And Sars-Cov-2, Mustafa Hasöksüz, Selçuk Kiliç, Fahri̇ye Saraç Jan 2020

Coronaviruses And Sars-Cov-2, Mustafa Hasöksüz, Selçuk Kiliç, Fahri̇ye Saraç

Turkish Journal of Medical Sciences

Coronaviruses (CoVs) cause a broad spectrum of diseases in domestic and wild animals, poultry, and rodents, ranging from mild to severe enteric, respiratory, and systemic disease, and also cause the common cold or pneumonia in humans. Seven coronavirus species are known to cause human infection, 4 of which, HCoV 229E, HCoV NL63, HCoV HKU1 and HCoV OC43, typically cause cold symptoms in immunocompetent individuals. The others namely SARS-CoV (severe acute respiratory syndrome coronavirus), MERS-CoV (Middle East respiratory syndrome coronavirus) were zoonotic in origin and cause severe respiratory illness and fatalities. On 31 December 2019, the existence of patients with pneumonia …

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Epidemiology Of Covid-19, Cemal Bulut, Yasuyuki̇ Kato Jan 2020

Epidemiology Of Covid-19, Cemal Bulut, Yasuyuki̇ Kato

Turkish Journal of Medical Sciences

It seems that coronaviruses take an important place in the 21th century history. Five of seven human coronavirus was isolated in this century. Unfortunately, last three of them entered our life with a fear of outbreak, pandemic or death. Last human coronavirus which emerged world from Wuhan China, SARS CoV-2 and its clinical expression, Coronavirus disease (COVID-19) recently taken a significant place in our daily practice. Initial reports showed that, its origin was bats. It transmitted human to human by droplet and contact routes, but some doubt about airborne, fecal or intrauterine transmission also should be removed. Its R0 value …

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Emerging And Reemerging Respiratory Viral Infections Up To Covid-19, İlhami̇ Çeli̇k, Esma Saatçi̇, Ayşegül Füsun Eyüboğlu Jan 2020

Emerging And Reemerging Respiratory Viral Infections Up To Covid-19, İlhami̇ Çeli̇k, Esma Saatçi̇, Ayşegül Füsun Eyüboğlu

Turkish Journal of Medical Sciences

Infectious diseases remain as the significant causes of human and animal morbidity and mortality, leading to extensive outbreaks and epidemics. Acute respiratory viral diseases claim over 4 million deaths and cause millions of hospitalizations in developing countries every year. Emerging viruses, especially the RNA viruses, are more pathogenic since most people have no herd immunity. The RNA viruses can adapt to the rapidly changing global and local environment due to the high error rate of their polymerases that replicate their genomes. Currently, coronavirus disease 2019 (COVID-19) is determined as an infectious disease caused by severe acute respiratory syndrome coronavirus 2 …

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Novel Coronavirus Disease (Covid-19) In Children, Hasan Tezer, Tuğba Bedi̇r Demi̇rdağ Jan 2020

Novel Coronavirus Disease (Covid-19) In Children, Hasan Tezer, Tuğba Bedi̇r Demi̇rdağ

Turkish Journal of Medical Sciences

Coronavirus disease (COVID-19) was firstly reported at the end of 2019. The disease rapidly spread all around the world in a few months and was declared a worldwide pandemic by WHO in March 2020. By April 9, there were 1,436,198 confirmed COVID-19 cases in the world, nearly with 6% mortality rate. This novel infectious disease causes respiratory tract illness that may generally occur as mild upper respiratory tract disease or pneumonia. In older patients and/or patients with underlying conditions, it may result in acute respiratory distress syndrome, multi organ failure and even death. According to the current literature, children account …

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Covid-19, Immune System Response, Hyperinflammation And Repurposingantirheumatic Drugs, Abdurrahman Tufan, Aslihan Avanoğlu Güler, Marco Matucci-Cerinic Jan 2020

Covid-19, Immune System Response, Hyperinflammation And Repurposingantirheumatic Drugs, Abdurrahman Tufan, Aslihan Avanoğlu Güler, Marco Matucci-Cerinic

Turkish Journal of Medical Sciences

In the Wuhan Province of China, in December 2019, the novel coronavirus 2019 (COVID-19) has caused a severe involvement of the lower respiratory tract leading to an acute respiratory syndrome. Subsequently, coronavirus 2 (SARS-CoV-2) provoked a pandemic which is considered a life-threatening disease. The SARS-CoV-2, a family member of betacoronaviruses, possesses singlestranded positive-sense RNA with typical structural proteins, involving the envelope, membrane, nucleocapsid and spike proteins that are responsible for the viral infectivity, and nonstructural proteins. The effectual host immune response including innate and adaptive immunity against SARS-Cov-2 seems crucial to control and resolve the viral infection. However, the severity …

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Supplementation With Aqueous Extract Of Talinum Triangulare And Effect On Thehematology And Serum Biochemistry In Growing Pullets, Chinwe Justina Aronu, Aruh Ottah Anaga, Benjamin Nwabueze Marire, Silvanus Maduka Anika Jan 2020

Supplementation With Aqueous Extract Of Talinum Triangulare And Effect On Thehematology And Serum Biochemistry In Growing Pullets, Chinwe Justina Aronu, Aruh Ottah Anaga, Benjamin Nwabueze Marire, Silvanus Maduka Anika

Turkish Journal of Veterinary & Animal Sciences

The effects of administration of Talinum triangulare aqueous extract on the hematology and serum biochemistry of growing pullets was studied. Ninety ISA Brown chicks purchased at 1 day old were randomly assigned into three groups: PA, PB, and PC. Pullets in groups PA and PB received 1000 mg of extract from dried T. triangulare and from freshly harvested T. triangulare per liter of water, respectively. Pullets in group PC served as the unsupplemented control. Hematology and serum biochemistry were evaluated at 2-month intervals within the 6-month period of the experiment following standard procedures. Feed and water were administered ad libitum. …

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Determination Of Fat Preferences Of Adult Dogs, Fatma İnal, Mustafa Selçuk Alataş, Oğuzhan Kahraman, Şeref İnal, Mustafa Uludağ Jan 2020

Determination Of Fat Preferences Of Adult Dogs, Fatma İnal, Mustafa Selçuk Alataş, Oğuzhan Kahraman, Şeref İnal, Mustafa Uludağ

Turkish Journal of Veterinary & Animal Sciences

This study was carried out to determine the preferences of dogs for some commonly used fat sources in dog food. Three different types of food were produced using 5% additional sunflower oil, poultry fat, or beef tallow. The food was extruded using a twin-screw extruder at approximately 25% moisture and temperatures in the range of 90 °C to 135 °C. The extrudates were dried for 30-45 min at temperatures of up to 148 °C in a belt dryer. Next, the heated fats were sprayed onto the extrudates. The foods were cooled, sampled, and packaged. A total of 30 neutered adult …

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Clinical Results Of Triple Tibial Osteotomy Treatment In Cranial Cruciateligament-Deficient Dogs, Mustafa Volkan Yaprakci, Zülfükar Kadi̇r Saritaş Jan 2020

Clinical Results Of Triple Tibial Osteotomy Treatment In Cranial Cruciateligament-Deficient Dogs, Mustafa Volkan Yaprakci, Zülfükar Kadi̇r Saritaş

Turkish Journal of Veterinary & Animal Sciences

Canine cranial cruciate ligament ruptures have become common with improved nutrition and nonselective breeding strategies. This study assessed 7 dogs of various breeds and ages with the diagnosis of cranial cruciate ligament ruptures. The triple tibial osteotomy (TTO) method was used to treat the rupture. All of the dogs were admitted to the clinic for varying degrees of lameness. Diagnosis was confirmed using both clinical and radiologic examinations. Body weights of the dogs were between 12 and 65 kg. Informed consent was given by the owners prior to surgery. Postoperatively, early evaluations were made using periodic radiographs and clinical examinations, …

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Effects Of Dietary Guar Meal With Or Without Beta-Mannanase On Performance And Eggquality Traits In Laying Hens, Süleyman Çalişlar Jan 2020

Effects Of Dietary Guar Meal With Or Without Beta-Mannanase On Performance And Eggquality Traits In Laying Hens, Süleyman Çalişlar

Turkish Journal of Veterinary & Animal Sciences

In this study, the effects of beta-mannanase supplementation to laying hens? diets with different guar meal (GM) ratios on performance and egg quality traits were investigated. The experimental period lasted 126 days. Ninety-six Lohman Brown hens at the age of 56 weeks were kept in individual cages. They were divided into 8 treatment groups as follows: 0% guar meal (GM0) (control); 0% GM + 0.05% beta-mannanase (GM0E); 8% GM (GM8); 8% GM + 0.05% beta-mannanase (GM8E); 16% GM (GM16); 16% GM + 0.05% beta-mannanase (GM16E); 24% GM (GM24); and 24% GM + 0.05% beta-mannanase (GM24E). A photoperiod of 16.5 h …

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Association Of Toll-Like Receptor 4 (Tlr 4) Gene Exon 3 Variants With Serostatus Of Theovine Johne's Disease (Paratuberculosis) In Turkish Sheep, Yalçin Yaman Jan 2020

Association Of Toll-Like Receptor 4 (Tlr 4) Gene Exon 3 Variants With Serostatus Of Theovine Johne's Disease (Paratuberculosis) In Turkish Sheep, Yalçin Yaman

Turkish Journal of Veterinary & Animal Sciences

In the present study, the effect of exon 3 of the toll-like receptor 4 (TLR4) gene on ovine Johne?s disease (OJD) serostatus was tested in Turkish sheep breeds. Initially, a retrospective cohort was performed using indirect ELISA on a commingled flock consisting of 3 native and 4 composite breeds (n = 1750). Case-control matched pairs were constructed according to the breed type and age (n = 188). Subsequently, exon 3 of the TLR4 gene was sequenced and coding variants were investigated. A total of 15 single nucleotide polymorphisms (SNPs) were detected and 12 of those SNPs were nonsynonymous. Next, 3 …

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The Anti Proliferative Effects Of Rosemary Oil On Keratinocyte Cell Line, Hacat, Muhammet Kuddusi̇ Erhan Jan 2020

The Anti Proliferative Effects Of Rosemary Oil On Keratinocyte Cell Line, Hacat, Muhammet Kuddusi̇ Erhan

Turkish Journal of Veterinary & Animal Sciences

This study aims to investigate the action of rosemary oil on the immortalized keratinocyte cell line. Samples of Rosmarinus officinalis that were growing uncultivated in central Turkey were harvested during flowering in May 2016. The rosemary oil was obtained by the hydrodistillation of the dried ground material in a Clevenger-like apparatus. Human cells from the immortalized nontumorigenic keratinocyte cell line were seeded at a concentration of 5000 cells/well on 96 well plates. Cell viability was measured at the 24, 48, and 72 h. Five different doses of 1.25% to 20% Rosmarinus officinalis oil, 20% DMSO (for toxic examination), and 1 …

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Evaluation Of Morgan's Pocket Technique In The Treatment Of Nictitans Gland Prolapse In Dogs, Mehmet Zeki̇ Yilmaz Deveci̇, Cafer Tayer İşler, Zi̇ya Yurtal, Muhammed Enes Altuğ, Ömer Kirgiz Jan 2020

Evaluation Of Morgan's Pocket Technique In The Treatment Of Nictitans Gland Prolapse In Dogs, Mehmet Zeki̇ Yilmaz Deveci̇, Cafer Tayer İşler, Zi̇ya Yurtal, Muhammed Enes Altuğ, Ömer Kirgiz

Turkish Journal of Veterinary & Animal Sciences

Nictitans gland prolapse (NGP), also known as third eyelid gland prolapse or cherry eye disease, is an important eye problem that should be treated as soon as possible in dogs. Although many surgical methods have been described, there is no consensus on the most effective technique. In this study, it was aimed to evaluate the characteristics of cases and clinical outcomes of Morgan's pocket technique in the treatment of dogs with NGP. In this context, the characteristics of the cases were examined in 25 dogs diagnosed (29 eyes) with NGP. Clinical results, recurrence, and complications were evaluated in 17 dogs …

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Statistical Analysis Of The Relationship Between Mortality And Nosocomial Factors Inpatients With Septicemia And The Importance Of Pseudomonas Aeruginosa, Di̇lek Dülger Jan 2020

Statistical Analysis Of The Relationship Between Mortality And Nosocomial Factors Inpatients With Septicemia And The Importance Of Pseudomonas Aeruginosa, Di̇lek Dülger

Turkish Journal of Veterinary & Animal Sciences

The ongoing evolution of sepsis as a condition constitutes a global health concern and necessitates continuous monitoring and investigation of incidence rates, mortality factors, and disease patterns. This study sought to elucidate the frequency of bacterial cultures in patients with septicemia at our hospital and identify the factors influencing mortality. Zoonotic risk factors with reference to the literature were also taken into account.Independent variables of all patients diagnosed with sepsis were retrospectively screened to reveal factors affecting mortality. Incomplete or unclear data were not included. Continuous variables are represented as means and standard deviations, whereas binary variables are represented as …

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