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Trajectory Of Trauma: The Experiences Of Black Girls In The School-To-Prison Pipeline, Heather Nicholson-Bester

Master's Theses and Doctoral Dissertations

This critical ethnographic research utilizes participatory action research (PAR) and case studies to explore the impacts that zero-tolerance policies have had on the lives of Black girls and women. This work contributes to a small but growing body of work on the intersectional struggles faced by Black girls within the School-to-Prison Pipeline. An aim of this research was to work with the participants to amplify their voices and center them as experts on their own lives. Working with a small sample of three girls and women enabled the creation of detailed narratives of their experiences. These narratives point to the …

Party For One: A Monologue Of The Importance Of Oneself Through Book Arts, Jacob Zhefu Wan

Electronic Theses and Dissertations, 2020-2023

This thesis explores the importance of oneself through sexuality, context, and introspection in the art of book arts. I work with memories, imagination, and consciousness in the form of book arts to express the importance of the self from my personal experience. Through the use of colors, materials, spatial compositions, and other visual components to manifest the content of my art, I want to illuminate the awareness of otherness including gender issues and an individual's vulnerability. Playing with the texts of Chinese and English, I intend to create narratives with languages, images, and other mixed media. In addition to crafting …

Paleoethnobotanical Analysis Of Starch Grains And Phytoliths From Pre-Columbian Ceramic Residues In The Bolivian Amazon, Danielle Young

Electronic Theses and Dissertations, 2020-2023

The Llanos de Mojos of the southwestern Amazon region of Bolivia once supported large Pre-Columbian indigenous populations who were regarded as skilled farmers, and whose agricultural pursuits are still documented on the landscape through tens of thousands of raised fields. Nevertheless, the plants that were cultivated on these fields that contributed to a large part of the local cuisine are not well understood. Microbotanical analyses using starch grains and phytoliths of food residues were conducted on 55 archaeological ceramic fragments from four forest islands in Mojos where people resided recurrently from cal BCE 1200 to cal CE ~1430. The results …

Learning Transferable Representations For Visual Recognition, Yang Zhang

Electronic Theses and Dissertations, 2020-2023

In the last half-decade, a new renaissance of machine learning originates from the applications of convolutional neural networks to visual recognition tasks. It is believed that a combination of big curated data and novel deep learning techniques can lead to unprecedented results. However, the increasingly large training data is still a drop in the ocean compared with scenarios in the wild. In this literature, we focus on learning transferable representation in the neural networks to ensure the models stay robust, even given different data distributions. We present three exemplar topics in three chapters, respectively: zero-shot learning, domain adaptation, and generalizable …

Early Host Defense Mechanisms Against La Crosse Virus Infection, Maria A. Cruz Zamora

Electronic Theses and Dissertations, 2020-2023

Given the importance of innate defense mechanisms in the skin, we have examined the interactions of the arbovirus La Crosse virus (LACV) with serum factors that serve as a first line of antiviral defense, and the outcome of LACV infection of human keratinocytes, one of the main cell types present at viral entry. Incubation of LACV derived from insect cells (I-LACV) with normal human serum in vitro did not result in neutralization, but instead stabilized LACV virions and enhanced infectivity. Enhanced infectivity was also seen with heat inactivated serum devoid of complement activity and with serum from a range of …

Navigating Immersive And Interactive Vr Environments With Connected 360° Panoramas, Samuel Cosgrove

Electronic Theses and Dissertations, 2020-2023

Emerging research is expanding the idea of using 360-degree spherical panoramas of real-world environments for use in "360 VR" experiences beyond video and image viewing. However, most of these experiences are strictly guided, with few opportunities for interaction or exploration. There is a desire to develop experiences with cohesive virtual environments created with 360 VR that allow for choice in navigation, versus scripted experiences with limited interaction. Unlike standard VR with the freedom of synthetic graphics, there are challenges in designing appropriate user interfaces (UIs) for 360 VR navigation within the limitations of fixed assets. To tackle this gap, we …

Fruits In Dakhleh: Isotopic And Bayesian Mixed-Model Reconstruction Of Food Source Contributions And Diet At Kellis 2 Cemetery, Dakhleh Oasis, Egypt, Melissa Gomez

Electronic Theses and Dissertations, 2020-2023

This thesis applies a new methodology to dietary reconstructions of a unique population excavated from Kellis 2, a Romano-Christian era (c.50-450 AD) cemetery located in the ancient city of Kellis, Dakhleh Oasis, Egypt. Previously, stable carbon and nitrogen isotope analyses were conducted on bulk hair keratin from 216 individuals to examine their dietary practices and health status. Although this research identified the presence of specific dietary choices in the community, the researchers were not able to determine what fraction of the diet was composed of those resources. This is the first such study to use a priori dietary reconstruction data …

The Policy On Children Of The Icc Office Of The Prosecutor: Toward Greater Accountability For Crimes Against And Affecting Children, Diane Marie Amann

Scholarly Works

The Policy on Children published by the International Criminal Court Office of the Prosecutor in 2016 represents a significant step toward accountability for harms to children in armed conflict and similar extreme violence. This article describes the process that led to the Policy and outlines the Policy’s contents. It then surveys relevant ICC practice and related developments, concluding that despite some salutary efforts, much remains to be done to recognize, prevent and punish the spectrum of conflicted-related crimes against or affecting children.

Removal Of Heavy Metals From Landfill Leachate Using Electrospun Polyelectrolyte Complex Fiber-Laminated Ultrafiltration Membrane, Amirsalar Rabbani Esfahani

Electronic Theses and Dissertations, 2020-2023

Ultrafiltration (UF) is a low-pressure membrane process that yields higher permeate flux and saves significant operating costs compared to NF/RO. However, UF has not been applied as a primary method for landfill leachate treatment due to its large pore size. This research investigated the removal of heavy metals from landfill leachate using an UF membrane laminated with fiber mats produced from electrospinning of a polyelectrolyte complex. In this research, we modified the surface of the UF membrane with two polyelectrolytes including Polyacrylic Acid (PAA) and Polyallylamine Hydrochloride (PAH). The removal of heavy metals including Pb, Cd, and Cu from water …

Data-Driven Identification Of Chemopreventive Agents For Breast Cancer, Deni̇z Can Güven, Cemal Orhan, Kazi̇m Şahi̇n, Fatih Mehmet Uçkun

Turkish Journal of Medical Sciences

Preclinical animal models of breast cancer provide the opportunity to identify chemopreventive drugs with single-agent activity as well as effective multi-modality regimens for primary as well as secondary prevention in high-risk persons. Our group has used the 7,12-dimethylbenz(a)anthracene (DMBA) mouse model of carcinogen-induced breast cancer to explore the clinical potential of two tyrosine kinase inhibitors and a nucleoside analog as chemopreventive agents. All three agents exhibited promising preclinical activity both as monotherapy and as components of combination therapy with the standard chemotherapy drug paclitaxel. The tumors developing despite chemoprevention were not only small and grew slowly, but they also displayed …

Effects Of Oral/Enteral Nutrition Alone Versus Plus Pantoprazole On Gastrointestinalbleeding In Critically Ill Patients With Low Risk Factor: A Multicenter, Randomizedcontrolled Trial, Kürşat Gündoğan, Emre Karakoc, Turgut Teke, Avşar Zerman, Ali̇ye Esmaoglu, Şahi̇n Temel, Muhammet Güven, Murat Sungur

Turkish Journal of Medical Sciences

Background/aim: Critically ill patients are at risk of developing gastrointestinal (GI) bleeding due to stress causing mucosal damage. Aim of the study was to determine the effect of oral/enteral nutrition with or without concomitant pantoprazole on upper GI bleeding in low risk critically ill patients. Materials and methods: This was a prospective, randomized, open-label, multicenter study conducted with intensive care unit (ICU) patients receiving oral/enteral nutritional support. Patients were randomly assigned into two groups including intervention group (received oral/EN plus pantoprazole) and control group (received only oral/EN). Results: A total of 300 patients (intervention group: 152, control group: 148) participated …

Comparison Of The Efficacy Between Bilateral Proximal Tubal Occlusion And Total Salpingectomy On Ovarian Reserve And The Cholinergic System: An Experimental Study, Remzi̇ Atilgan, Şehmus Pala, Tuncay Kuloğlu, Cengi̇z Şanli, Şeyda Yavuzkir, Zehra Sema Özkan

Turkish Journal of Medical Sciences

Background and aim: To compare the effects of bilateral proximal tubal occlusion and bilateral total salpingectomy on ovarian reserve and the cholinergic system via rat experiment. Materials and methods: Twenty-one adult female rats were randomly divided into the following three groups: G1 (n = 7), sham group; G2 (n = 7), bilateral total salpingectomy group; and G3 (n = 7), bilateral proximal tubal occlusion group. Four weeks later, the abdomen of the rats was opened. The right ovarian tissues were stored in 10% formaldehyde, whereas the left ovarian tissues were stored at ?80 °C in aluminum foil. Serum samples were …

Omics Era In Forensic Medicine: Towards A New Age, Ramazan Akçan, Burak Taşteki̇n, Mahmut Şeri̇f Yildirim, Hali̇t Canberk Aydogan, Necdet Sağlam

Turkish Journal of Medical Sciences

Background/aim: Forensic medicine and sciences is a multidisciplinary branch of science, which frequently benefit from novel technologies. State of the art omics technologies have begun to be performed in forensic medicine and sciences, particularly in postmortem interval, intoxication, drugs of abuse, diagnosis of diseases and cause of death. This review aims to discuss the role and use of great omics (metabolomics, proteomics, genomics and transcriptomics) in forensic sciences, in detail. Materials and methods: A detailed review of related literature was performed, and studies were subdivided as per the type of omics.Results and conclusion: Omics seems as a revolutionary step in …

Tetanus Vaccine During Pregnancy: Data Of A Tertiary Hospital In Turkey, Gülşah Dağdevi̇ren, Gökçen Örgül, Aykan Yücel, Di̇lek Şahi̇n

Turkish Journal of Medical Sciences

Background/aim: To evaluate the prevalence of tetanus vaccination in pregnant women and determine the factors affecting the vaccination and barriers to vaccination. Materials and methods: An observational-descriptive study was conducted on 494 women who gave birth at the Etlik Zübeyde Hanım Women's Health Training and Research Hospital, Ankara, Turkey. Participants were divided into 2 groups, vaccinated and unvaccinated. Sociodemographic characteristics, obstetric history, and prenatal care status were compared between the 2 groups. Results: There were 242 (48.9%) and 252 (51.1%) women in the vaccinated and unvaccinated groups, respectively. The vaccination rate decreased as the number of pregnancies increased (P = …

Sdg 3: Good Health And Well-Being - Framing Targets To Maximise Co-Benefits For Forests And People, Rosemary A. Mcfarlane, John Barry, Guéladio Cissé, Maya Gislason, Marta Gruca, Kerryn Higgs, Pierre Horwitz, Giang Nguyen, Jane O'Sullivan, Subhashis Sahu, Colin D. Butler

Research outputs 2014 to 2021

Key Points: The achievement of SDG 3 depends on many other SDGs; some SDGs are logically inconsistent, especially in the attempt to increase conventionally defined GDP while preserving natural capital. Any short-term gains for human health from further forest conversion (e.g. food production) creates short- and long-term, direct and indirect health risks for humans, as well as for other biota. Failure to ensure universal access to sexual and reproductive healthcare services (including family planning) will increase pressure on forests at local, regional and global scales. The burning and clearing of forests cause significant harm to health via impaired quality of …

An Insight Into The Epitope-Based Peptide Vaccine Design Strategy And Studies Against Covid-19, Murat Topuzoğullari, Tayfun Acar, Peli̇n Peli̇t Arayici, Burcu Uçar, Erennur Uğurel, Emrah Şefi̇k Abamor, Tüli̇n Arasoğlu, Di̇lek Balik, Serap Derman

Turkish Journal of Biology

SARS-CoV-2 is a new member of the coronavirus family and caused the pandemic of coronavirus disease 2019 (COVID-19) in 2020. It is crucial to design and produce an effective vaccine for the prevention of rapid transmission and possible deaths wcaused by the disease. Although intensive work and research are being carried out all over the world to develop a vaccine, an effective and approved formulation that can prevent the infection and limit the outbreak has not been announced yet. Among all types of vaccines, epitope-based peptide vaccines outshine with their low-cost production, easy modification in the structure, and safety. In …

Today And Yesterday, Vol. 44, 2020, Illinois State University, Department Of History

Today and Yesterday

Newsletter of the Illinois State University Department of History

Religious Freedom And The Churches: Contemporary Challenges In The United States Today, Richard W. Garnett

Journal Articles

A crucial, but often overlooked, dimension of the human and constitutional right to religious freedom is the autonomy of religious institutions, associations and societies with respect to matters of governance, doctrine, formation and membership. Although the Supreme Court of the United States has affirmed this autonomy in the context of American constitutional law, it is vulnerable, and even under threat, for a variety of reasons, including a general decline in the health of civil society and mediating associations and a crisis of confidence and authority caused by clerical sexual abuse and churches’ failure to respond to it.

Conscience And Justice In Equity: Comments On Equity: Conscience Goes To Market, Paul B. Miller

Journal Articles

This short essay introduces and engages several philosophical questions raised by Irit Samet’s Equity: Conscience Goes to Market. Amongst other things, it addresses questions going to: the proper scope of equity; the relationship between equity’s remedial and supplemental functions; whether, and if so, to what extent equity promotes compliance with moral obligations; what, if any, moral aims animate equitable intervention; and whether, and if so, how, equity is distinctively concerned with matters of conscience and “particular” justice. All the while, I express appreciation for Samet’s project while raising some doubts about her views on how law and equity divide labor …

Against Fiduciary Constitutionalism, Samuel L. Bray, Paul B. Miller

Journal Articles

A growing body of scholarship draws connections between fiduciary law and the Constitution. In much of this literature, the Constitution is described as a fiduciary instrument that establishes fiduciary duties, not least for the President of the United States. This Article examines and critiques the claims of fiduciary constitutionalism. Although a range of arguments are made in this literature, there are common failings. Some of these involve a literalistic misreading of the works of leading political philosophers (e.g., Plato and Locke). Other failings involve fiduciary law—mistakes about how to identify fiduciary relationships, about the content and enforcement of fiduciary duties, …

Nr2e3 Is A Genetic Modifier That Rescues Retinal Degeneration And Promotes Homeostasis In Multiple Models Of Retinitis Pigmentosa, Sujun Li, Shyamtanu Datta, Emily Brabbit, Zoe Love, Victoria Woytowicz, Kyle Flattery, Jessica Capri, Katie Yao, Siqi Wu, Michael Imboden, Arun Upadhyay, Rasappa Arumugham, Wallace B. Thoreson, Margaret M Deangelis, Neena B. Haider

Journal Articles: Ophthalmology

Recent advances in viral vector engineering, as well as an increased understanding of the cellular and molecular mechanism of retinal diseases, have led to the development of novel gene therapy approaches. Furthermore, ease of accessibility and ocular immune privilege makes the retina an ideal target for gene therapies. In this study, the nuclear hormone receptor gene Nr2e3 was evaluated for efficacy as broad-spectrum therapy to attenuate early to intermediate stages of retinal degeneration in five unique mouse models of retinitis pigmentosa (RP). RP is a group of heterogenic inherited retinal diseases associated with over 150 gene mutations, affecting over 1.5 …

Conflicts And Triage, Kate E. Lynch, Daniel T. Blumstein

Animal Sentience

To represent diverse interests successfully, a strategy for dealing with conflicts is needed. We discuss an approach to maximizing the interests of the greatest number of individuals, present and future.

On The Rhetorical Grotesque: A Mode For Strange Times, Richard Benjamin Crosby

Faculty Publications

This essay argues that the successful political careers of certain populist leaders rhetorically enact what scholars have long recognized in art, literature, and entertainment as the grotesque. The grotesque provides a theoretically rich means for describing the vulgar and chaotic public behaviors that take strong hold among anti-elite audiences at certain points in history. By closely reading comments from political leaders cast in the grotesque mold, including Silvio Berlusconi, Hugo Chavez, and Donald Trump, this essay explains not only what the grotesque is, but also when and how it is likely to find traction in a political culture ripe for …

A High Docosahexaenoic Acid Diet Alters The Lung Inflammatory Response To Acute Dust Exposure, Edward C. Dominguez, Art J. Heires, Jacqueline A. Pavlik, Tricia D. Larsen, Stephanie Guardado, Joseph H. Sisson, Michelle L. Baack, Debra J. Romberger, Tara M. Nordgren

Journal Articles: Internal Medicine

Agricultural workers are at risk for the development of acute and chronic lung diseases due to their exposure to organic agricultural dusts. A diet intervention using the omega-3 fatty acid docosahexaenoic acid (DHA) has been shown to be an effective therapeutic approach for alleviating a dust-induced inflammatory response. We thus hypothesized a high-DHA diet would alter the dust-induced inflammatory response through the increased production of specialized pro-resolving mediators (SPMs). Mice were pre-treated with a DHA-rich diet 4 weeks before being intranasally challenged with a single dose of an extract made from dust collected from a concentrated swine feeding operation (HDE). …

Myd88 Regulates A Prolonged Adaptation Response To Environmental Dust Exposure-Induced Lung Disease, Amber N. Johnson, Jack R. Harkema, Amy J. Nelson, John D. Dickinson, Julianna Kalil, Michael J. Duryee, Geoffrey M. Thiele, Balawant Kumar, Amar B. Singh, Rohit Gaurav, Sarah C. Glover, Ying Tang, Debra J. Romberger, Tammy Kielian, Jill A. Poole

Journal Articles: Internal Medicine

BACKGROUND: Environmental organic dust exposures enriched in Toll-like receptor (TLR) agonists can reduce allergic asthma development but are associated with occupational asthma and chronic bronchitis. The TLR adaptor protein myeloid differentiation factor88 (MyD88) is fundamental in regulating acute inflammatory responses to organic dust extract (ODE), yet its role in repetitive exposures is unknown and could inform future strategies.

METHODS: Wild-type (WT) and MyD88 knockout (KO) mice were exposed intranasally to ODE or saline daily for 3 weeks (repetitive exposure). Repetitively exposed animals were also subsequently rested with no treatments for 4 weeks followed by single rechallenge with saline/ODE.

RESULTS: Repetitive …

From Individual Control To Social Protection: New Paradigms For Privacy Law In The Age Of Predictive Analytics, Dennis D. Hirsch

Maryland Law Review

No abstract provided.

Drawing The Line: A First Amendment Framework For Partisan Gerrymandering In The Wake Of Rucho V. Common Cause, Kyle Keraga

Maryland Law Review

No abstract provided.

Targeting The Tumor Core: Hypoxia-Responsive Nanoparticles For The Delivery Of Chemotherapy To Pancreatic Tumors, Matthew I. Confeld, Babak Mamnoon, Li Feng, Heather Jensen Smith, Priyanka Ray, James Froberg, Jiha Kim, Michael A. Hollingsworth, Mohiuddin Quadir, Yongki Choi, Sanku Mallik

Journal Articles: Eppley Institute

In pancreatic ductal adenocarcinoma (PDAC), early onset of hypoxia triggers remodeling of the extracellular matrix, epithelial-to-mesenchymal transition, increased cell survival, the formation of cancer stem cells, and drug resistance. Hypoxia in PDAC is also associated with the development of collagen-rich, fibrous extracellular stroma (desmoplasia), resulting in severely impaired drug penetration. To overcome these daunting challenges, we created polymer nanoparticles (polymersomes) that target and penetrate pancreatic tumors, reach the hypoxic niches, undergo rapid structural destabilization, and release the encapsulated drugs. In vitro studies indicated a high cellular uptake of the polymersomes and increased cytotoxicity of the drugs under hypoxia compared to …

Tlr2 And Caspase-1 Signaling Are Critical For Bacterial Containment But Not Clearance During Craniotomy-Associated Biofilm Infection, Amy L. Aldrich, Cortney E. Heim, Wen Shi, Rachel W. Fallet, Bin Duan, Tammy Kielian

Journal Articles: Pathology and Microbiology

BACKGROUND: A craniotomy is required to access the brain for tumor resection or epilepsy treatment, and despite precautionary measures, infectious complications occur at a frequency of 1-3%. Approximately half of craniotomy infections are caused by Staphylococcus aureus (S. aureus) that forms a biofilm on the bone flap, which is recalcitrant to antibiotics. Our prior work in a mouse model of S. aureus craniotomy infection revealed a critical role for myeloid differentiation factor 88 (MyD88) in bacterial containment and pro-inflammatory mediator production. Since numerous receptors utilize MyD88 as a signaling adaptor, the current study examined the importance of Toll-like receptor 2 …

Rewilding And Domestication: Clarifying Terminology, Catia Correia-Caeiro

Animal Sentience

Baker & Winkler (B&W) describe the state of Asian elephant conservation, raising unique issues, and proposing a direction based on rewilding. The long history and socio-biology of elephants and humans has some parallels with the domestication of dogs (and other species). However, markers of domestication seem absent from elephants. The proper use of terms such as “wild” and “domestic” is crucial in defining the best conservation strategies, and, more important, in attending to the welfare needs of individuals, which can differ between wild and domestic animals. B&W’s target article represents an important starting point for discussion around elephant conservation, but …