Digital Commons Network^™

Single-Nuclei Multiomics Analysis Identifies Abnormal Cardiomyocytes In A Murine Model Of Cardiac Development., Riley Leonard, Yi Zhao, Steven Eliason, Kathy Zimmerman, Ariana Batz, Cathy J. Hatcher, Robert M Weiss, Mason Sweat, Xiao Li, Brad A Amendt

PCOM Scholarly Works

Transcription factors such as Tbx5, Gata4, Mef2c and Pitx2 are required during cardiac development, and in adult cardiac homeostasis. We demonstrate that the gene dosage and modulation of these factors are mediated in vivo by the miR-200 family. Inhibition of a single miR-200 family member within the cluster results in defects of the left ventricle and cardiomyocyte maturation during development. Inhibition of the entire miR-200 family results in a ventricular septal defect and embryonic lethality by embryonic day (E)16.5. Inhibition of each miR-200 family has distinct heart phenotypes in cell specific differentiation and maturation. snRNA-sequencing reveals an immature cardiomyocyte cell …

Cocoa Polyphenols Alter The Fecal Microbiome Without Mitigating Colitis In Mice Fed Healthy Or Western Basal Diets, Eliza C. Stewart, Mohammed F. Almatani, Marcus Hayden, Giovanni Rompato, Jeremy Case, Samuel Rice, Korry J. Hintze, Abby D. Benninghoff

Animal, Dairy, and Veterinary Science Student Research

Background/Objectives: Chronic inflammation and Western-style diets elevate colorectal cancer (CRC) risk, particularly in individuals with colitis, a feature of inflammatory bowel disease (IBD). Diets rich in polyphenol-containing functional foods, such as cocoa, may reduce gut inflammation and modulate the gut microbiome. This study investigated the impact of cocoa polyphenol (CP) supplementation on inflammation and microbiome composition in mice with colitis, fed either a healthy or Western diet, before, during, and after the onset of disease. We hypothesized that CPs would attenuate inflammation and promote distinct shifts in the microbiome, especially in the context of a Western diet. Methods: …

Reviving The Lost Art: Historical Foundations And Future Pathways For Bespoke Service In Luxury Retail, Andrew Burnstine

Faculty and Staff Publications & Presentations

The mid-20th century witnessed a zenith of deeply personalized, bespoke service within iconic luxury specialty retailers. This paper critically analyzes the foundational principles of this historical bespoke service model, extending Service-Dominant (S-D) Logic and retail evolution theory, to propose a robust framework for its modern revival. Employing a rigorous qualitative, multiple-case study approach, grounded in extensive historical and media analysis of four archetypal American and British luxury boutiques, and uniquely informed by an insider-ethnographic perspective on the central case exemplar ("Martha's"), the study distills six core principles: Profound Client Knowledge, Visionary Curation & Styling, Anticipatory & Proactive Service, The Exclusive …

Sleep Drive, Not Total Sleep Amount, Increases Seizure Risk, Vishnu Anand Cuddapah, Cynthia T Hsu, Fernanda Valle Sirias, Yongjun Li, Hrishit M Shah, Christopher Saul, Samantha Killiany, Camilo Guevara, Joy Shon, Zhifeng Yue, Gabrielle L Gionet, Mary E Putt, Amita Sehgal

Duncan NRI Faculty and Staff Publications

Sleep loss has been associated with increased seizure risk since antiquity. Using automated video detection of spontaneous seizures in Drosophila epilepsy models, we show that seizures worsen only when sleep restriction raises homeostatic "sleep drive," not simply when total sleep amount falls. This is supported by the paradoxical finding that acute activation of sleep-promoting circuits worsens seizures, because it increases sleep drive without changing sleep amount. Sleep-promoting circuits become hyperactive after sleep loss and are associated with increased whole-brain activity. During sleep restriction, optogenetic inhibition of sleep-promoting circuits to reduce sleep drive protects against seizures. Downregulation of the 5HT1A serotonin …

Transforming Cancer Care: A Narrative Review On Leveraging Artificial Intelligence To Advance Immunotherapy In Underserved Communities, Victor M. Vasquez Jr., Molly Mccabe, Jack C. Mckee, Sharon Siby, Usman Hussain, Farah Faizuddin, Aadil Sheikh, Subramanian Dhandayuthapani, Shrikanth Gadad, Jessica Chacon

School of Medicine Publications

Purpose: Cancer immunotherapy has transformed oncology, but underserved populations face persistent disparities in access and outcomes. This review explores how artificial intelligence (AI) can help mitigate these barriers. Methods: We conducted a narrative review based on peer-reviewed literature selected for relevance to artificial intelligence, cancer immunotherapy, and healthcare challenges, without restrictions on publication date. We searched three major electronic databases: PubMed, IEEE Xplore, and arXiv, covering both biomedical and computational literature. The search included publications from January 2015 through April 2024 to capture contemporary developments in AI and cancer immunotherapy. Results: AI tools such as machine learning, …

Fictitious Data-Based Watermarking System

Defensive Publications Series

Systems and methods are provided for watermarking via unique synthetic datasets. A candidate model may be trained with a poison dataset including synthetic information. The synthetic information may relate to a fictitious place, person, or scenario, for example. A set of one or more inference questions associated with the poison dataset may be determined. The candidate model may be tested based on the set of one or more inference questions. A confidence may also be generated. The confidence may be associated with one or more identification metrics associated with the candidate model.

Will In Western Thought; An Historico-Critical Survey, Vernon J. Bourke

Hannah Arendt Marginalia - All

New York, Sheed and Ward [1964]

Call #: BD450 .B64

Contains marginalia, underlining, and marginal lining

PDF Information: 39 pages – 35 MB

Selected Poems, Bertolt Brecht

Hannah Arendt Marginalia - All

New York, Reynal & Hitchcock [1947]

Call #: PT2603.R397 A24 1947

Arendt copy contains marginalia, underlining , marginal lining and endpaper notes

PDF Information: 44 pages – 2 MB

The Effect Of A Therapy Dog On Pressure Pain Threshold In Healthy Individuals, Lydia L. Haak, Rhonda L. Verdegan

Internet Journal of Allied Health Sciences and Practice

Purpose: Pain is the most common reason for healthcare consultation in the United States. Pain affects every area of life; biologically, psychologically, and socially. These three constructs make up every individual and thus contribute to their perceived quality of life. The use of therapy dogs (TD) has been widely researched as a source of non-pharmacological pain management. Studies have proven that a dog can reduce perceived pain in people with a variety of comorbidities. The purpose of this study was to prove that pain is modulated biologically by dogs and not just by human perception. Methods: This was …

Understanding The Relationship Between Occupation And Cognitive Abilities: A Preliminary Study, Deepak Puttanna, Srinidhi Konda, Mohammed Al Harbi

Internet Journal of Allied Health Sciences and Practice

Purpose: Understanding the cognitive abilities across various occupational backgrounds is deemed crucial, owing to the fact that the cognitive load imposed in each of the roles varies, thus there may be different levels of cognitive skills used in daily day-to-day activities. Also, it paves the way for the researchers to understand how an intellectually stimulating environment aids in better cognitive reserve or hinders cognitive decline. Method: A total of 60 participants aged between 30 to 50 years participated in the study. These participants were further divided into two broad groups, professional/technical workers and structural work occupations. These occupations were …

The Two Sources Of Morality And Religion, Henri Bergson

Hannah Arendt Marginalia - All

Garden City, N.Y. : Doubleday Anchor, 1935

Call #: B2430.B4 D42 1954

Contains marginalia, underlining, margin lining and endpaper notes.

PDF Information: 16 pages – 5.3mb

Praxis And Action; Contemporary Philosophies Of Human Activity, Richard J. Bernstein

Hannah Arendt Marginalia - All

Philadelphia: University of Pennsylvania Press, 1971

Call #: BD450 .B44

Marginalia, marginal lining and underlining.

PDF Information: 15 pages – 7mb

Duns Scotus: The Basic Principles Of His Philosophy, Efrem Bettoni

Hannah Arendt Marginalia - All

Washington, Catholic University of America Press, 1961

Call #: B765.D74 B43

Contains underling, marginal lining and endpaper notes

PDF Information: 27 pages – 12 MB

Atomic Physics And Human Knowledge, Niels Bohr

Hannah Arendt Marginalia - All

New York : Wiley, 1958.

Call#: QC6 .B598

Contains underlining and marginal lining

PDF Information: 29 pages - 2.3MB

Teachers’ Talk About Children’S Texts, Sarah J. Mccarthey, Ngan Vu, Jiadi Zhang

Teaching/Writing: The Journal of Writing Teacher Education

Using a framework for discourses about writing, the qualitative study investigates teachers’ discussions about student texts during focus group sessions. The setting was a small, private school with a diverse student population and teachers who shared an approach to teaching. Their discussions focused on aspects of student writing including word choice and voice; learning to write within genres such as narrative, opinion, and poetry; and writing for an audience. Teachers valued multimodality by emphasizing how pictures and text can support one another throughout the writing process. The data reflect teachers’ knowledge of the students as writers and their cultural and …

The Political Thought Of Plato And Aristotle, Ernest Barker Sir

Hannah Arendt Marginalia - All

New York : Dover Publication, 1959

Call #: JC72 .B26

Contains underlining

PDF Information: 10 pages – 3.5 MB

The Romans, R.H. Barrow

Hannah Arendt Marginalia - All

Harmondsworth, Middlesex: Penguin Books, 1953

Call #: DG77 .B34 1953

Contains underlining & marginal lining.

PDF Information: 73 pages – 64mb

Work And Its Discontents, Daniel Bell

Hannah Arendt Marginalia - All

Boston : Beacon Press, [1956]

Call #: HD4904 .B44

Contains marginalia, underlining and marginal lining

PDF information: 25 pages – 1.4 MB

Essays By Locke, Hume, And Rousseau, Ernest Barker Sir

Hannah Arendt Marginalia - All

New York, Oxford University Press, 1962

Call #: JC336 .B27 1962

Contains marginal lining Contained ephemera. 5 x 3 in. notepad page inserted in book with brief notes pertaining to the text. See Arendt ephemera file, folder 005.

PDF Information: 17 pages – 1.2 MB

Cowboy Narrative - Richard Murphy, Sheldon F. Gauthier, Richard Murphy

Writers' Program of the Work Projects Administration in the State of Texas, Fort Worth City Guide and History Draft Records

A transcript of a Cowboy Narrative, or Rangelore, interview conducted by Sheldon F. Gauthier for the Works Progress Administration's Federal Writers' Project in the 1930s with former cowboy Richard Murphy. Murphy was born in Slap out, Brown County, Texas in 1885 and moved to Haskell County at a young age. He began working for the T Diamond outfit at age 11 and worked as a cowhand. In his interview, he describes being inexperienced or "green" in the field, roundups, riding, shooting, stampedes, trail drives, and dealing with rustlers and Native Americans. He also discusses the culture of the range, including …

Cowboy Narrative - J. G. Mooring, Sheldon F. Gauthier, J. G. Mooring

Writers' Program of the Work Projects Administration in the State of Texas, Fort Worth City Guide and History Draft Records

A transcript of a Cowboy Narrative, or Rangelore, interview conducted by Sheldon F. Gauthier for the Works Progress Administration's Federal Writers' Project in the 1930s with former cowboy J. G. Mooring. Mooring was born on his father's ranch in Rains County, Texas in 1868 and learned to ride a horse and perform the duties of a cowhand at a young age. In his interview, he discusses various aspects of working as a cowhand, including horse riding and busting, roundups, treating "screw worms", and how the brushy terrain of Rains County impacted the cattle. He also describes ranchers' dealings with rustlers …

Cowboy Narrative - Robert S. Miller, Sheldon F. Gauthier, Robert S. Miller

Writers' Program of the Work Projects Administration in the State of Texas, Fort Worth City Guide and History Draft Records

A transcript of a Cowboy Narrative, or Rangelore, interview conducted by Sheldon F. Gauthier for the Works Progress Administration's Federal Writers' Project in the 1930s with former cowboy Robert S. Miller. Miller was born on his father's ranch in Williamson County, Texas in 1858 and later moved to Stephens County. In his interview, he describes the effect of the Civil War on his father's ranch while he was away in the Confederate Army. He also describes various aspects of working on the range, including sales, food culture, dealings with rustlers and Native Americans, stampedes, blizzards, and various economic crises and …

Cowboy Narrative - Supplement To Robert S. Miller's Interview, Sheldon F. Gauthier, Robert S. Miller

Writers' Program of the Work Projects Administration in the State of Texas, Fort Worth City Guide and History Draft Records

A transcript of a supplement to a Cowboy Narrative, or Rangelore, interview conducted by Sheldon F. Gauthier for the Works Progress Administration's Federal Writers' Project in the 1930s with former cowboy Robert S. Miller. The supplement adds further information to Miller's main interview, including information about buffalo and buffalo hunting in "No Man's Land" (present-day Oklahoma) and wildfires.

Cowboy Narrative - James W. Mathis, Sheldon F. Gauthier, James W. Mathis

Writers' Program of the Work Projects Administration in the State of Texas, Fort Worth City Guide and History Draft Records

A transcript of a Cowboy Narrative, or Rangelore, interview conducted by Sheldon F. Gauthier for the Works Progress Administration's Federal Writers' Project in the 1930s with former cowboy James W. Mathis. Mathis was born in Logan County, Arkansas, and relocated with his parents to Burnet County, Texas in 1885 when Mathis was 12 years old. He worked at his grandfather's ranch, Sherly Ranch in Burnet as a cowboy upon his arrival. In his interview, he describes transportation in wagons and trains, milking cows, parasites, cattle sales, roundups, branding, and various entertainment that cowhands engaged in during their downtime, including poker, …

Cowboy Narrative - Tom Mcclure, Woody Phipps, Tom Mcclure

Writers' Program of the Work Projects Administration in the State of Texas, Fort Worth City Guide and History Draft Records

A transcript of a Cowboy Narrative, or Rangelore, interview conducted by Woody Phipps for the Works Progress Administration's Federal Writers' Project in the 1930s with former cowboy Tom McClure. McClure was born on his father's stock farm in Wise County, Texas. He grew up working on the ranch, and eventually went to work on trail drives for Andy Coston, who had a government contract to supply the Indian Territory with beef. He describes trail drives, stampedes, fording rivers, and roping contests. He later became a peace officer and sheriff known as the "Six shooter-less Sheriff" because he never carried a …

Cowboy Narrative - Dave May, Woody Phipps, Dave May

Writers' Program of the Work Projects Administration in the State of Texas, Fort Worth City Guide and History Draft Records

A transcript of a Cowboy Narrative, or Rangelore, interview conducted by Woody Phipps for the Works Progress Administration's Federal Writers' Project in the 1930s with former cowboy Dave May. May was born on his father's ranch 20 miles West of Waco, Texas. In his interview he describes horse and cattle thievery known as "rustling", lynchings, stampedes, roundups, and food culture on the range.

Cowboy Narrative - Walter R. Morrison, Sheldon F. Gauthier, Walter R. Morrison

Writers' Program of the Work Projects Administration in the State of Texas, Fort Worth City Guide and History Draft Records

A transcript of a Cowboy Narrative, or Rangelore, interview conducted by Sheldon F. Gauthier for the Works Progress Administration's Federal Writers' Project in the 1930s with former cowboy Walter R. Morrison. Morrison was born in Mineola, Wood County, Texas, where his father owned a lumber mill. From a young age, he rode horses, and at the age of 14 he joined a cattle drive passing his home. In the interview, he describes learning to ride pitching horses, riding at night, stampedes, battles with Native Americans, problems with rustlers, and participating in early organized rodeos in Fort Worth. He worked at …

Cowboy Narrative - James M. Mooney, Sheldon F. Gauthier, James M. Mooney

Writers' Program of the Work Projects Administration in the State of Texas, Fort Worth City Guide and History Draft Records

A transcript of a Cowboy Narrative, or Rangelore, interview conducted by Sheldon F. Gauthier for the Works Progress Administration's Federal Writers' Project in the 1930s with former cowboy James M. Mooney. Mooney was born in Abbeville, Mississippi, but moved with his father to Scurry County, Texas at a young age. Scurry's father established a ranch on Deep Creek. From a young age, Mooney rode horses and performed cowhand duties around the ranch. By age 13 he served as a full-time ranch hand, and by age 19 he was the "trail boss" for his father's outfit. In the interview, he describes …

Cowboy Narrative - John T. "Sad" Gardenhire, Woody Phipps, John T. "Sad" Gardenhire

Writers' Program of the Work Projects Administration in the State of Texas, Fort Worth City Guide and History Draft Records

A transcript of a Cowboy Narrative, or Rangelore, interview conducted by Woody Phipps for the Works Progress Administration's Federal Writers' Project in the 1930s with former cowboy John T. "Sad" Gardenhire. Gardenhire was born near Rockwall in present-day Rockwall County, Texas. He attended school until age 18, then worked as a cowhand for nearly thirty years. In his interview, he discussed the Civil War's effect on cattle ranching, stampedes, cattle drives, shootouts, rustling, and branding. He also describes and names several cowhands he worked with at the US Ranch in Stephens and then Baylor County. After retiring from ranching, he …

Cowboy Narrative - John M. Hardeman, Sheldon F. Gauthier, John M. Hardeman

Writers' Program of the Work Projects Administration in the State of Texas, Fort Worth City Guide and History Draft Records

A transcript of a Cowboy Narrative, or Rangelore, interview conducted by Sheldon F. Gauthier for the Works Progress Administration's Federal Writers' Project in the 1930s with former cowboy John M. Hardeman. Hardeman, whose uncle, J. Baily Hardeman, was a signer of the Texan Declaration of Independence, was born in Robertson County, Texas. His father moved the family to Williamson County, between Round Rock and Taylorville (now Taylor). The majority of the interview consists of Hardeman reciting information about various families and public servants in the early days of Taylor. He discusses killings, shootouts, feuds, and court cases. He also briefly …