Digital Commons Network^™

Poverty, People & Politics: A Multimedia Project On Poverty In The City Of Syracuse, Gabrielle Caracciolo

Renée Crown University Honors Thesis Projects - All

No abstract provided.

Reviving The Rust-Belt: An Environmental Design Project, Yunqian Li

Renée Crown University Honors Thesis Projects - All

No abstract provided.

The Emergence And Perpetuation Of Alienation In Capitalist Contexts, Elizabeth Gostev

Renée Crown University Honors Thesis Projects - All

No abstract provided.

Contraception And Sexual Health Counseling In Adolescent And Young Adult Female Cancer Patients, Sarah Hadassah Abelman

Yale Medicine Thesis Digital Library

Introduction:

Adolescent and young adult women undergoing cancer treatment face unique reproductive health risks. The objectives of this study were to assess the prevalence of sexual health counseling and contraception use in the oncology setting, and to identify factors associated with these outcomes.

Methods:

After institutional review board approval, a retrospective chart review was conducted of female patients ages 15-25 receiving cancer treatment at Yale New Haven Hospital from 2013-2018. Univariate and multivariate analyses were used to assess the relationship between patient variables and the outcomes of counseling and contraception use. Additionally, with institutional review board approval, a cross-sectional survey …

Approaches To Fracture Healing Under Inflammatory Conditions: Infection And Diabetes, Sean Vincent Cahill

Yale Medicine Thesis Digital Library

Non-union is a devastating complication of fracture and can be precipitated by abnormal

inflammatory states including infection and diabetes.

This thesis focuses on four related research problems that are addressed through original

scientific investigation and literature review. In addressing these questions, this dissertation

presents evidence for the following conclusions through in vivo animal models and using methods

including bacterial cell culture and counting, histology, radiography, and micro-computed

tomography:

1. Rifampin-loaded hydrogels decrease bacterial load and improve fracture healing in

a MRSA-infected open fracture model.

2. MRSA-infected nonunion is characterized by impaired chondrocyte maturation and

is associated with IL-1 and NF-KB …

Differential Response To Rituximab In Anti-Achr And Anti-Musk Positive Myasthenia Gravis Patients, Tess Litchman

Yale Medicine Thesis Digital Library

Response to immunomodulatory therapies in myasthenia gravis (MG) can be variable. A subset of MG patients remains refractory to conventional agents. B-cell targeted therapy with rituximab has demonstrated a durable response in treating refractory myasthenia gravis (MG). This study compares the response to rituximab between patients with acetylcholine receptor autoantibody positive (AChR+) and muscle-specific kinase autoantibody positive (MuSK+) MG.

This retrospective study included 33 patients with either AChR+ or MuSK+ MG who were treated with rituximab from 05/31/2003 to 05/31/2017. Pretreatment and post-treatment immunotherapy regimens, clinical symptoms, and examination findings were evaluated.

Median MGFA Class of II at baseline improved …

Forecast, 2020, Illinois State University, College Of Applied Science And Technology

foreCAST

Magazine of the Illinois State University College of Applied Science and Technology

Trypanosomatids Detected In The Invasive Avian Parasite Philornis Downsi (Diptera: Muscidae) In The Galapagos Islands, Patricia Parker, Courtney Pike, María Piedad Lincango, Charlotte Causton

Biology Department Faculty Works

Alien insect species may present a multifaceted threat to ecosystems into which they are introduced. In addition to the direct damage they may cause, they may also bring novel diseases and parasites and/or have the capacity to vector microorganisms that are already established in the ecosystem and are causing harm. Damage caused by ectoparasitic larvae of the invasive fly, Philornis downsi (Dodge and Aitken) to nestlings of endemic birds in the Galapagos Islands is well documented, but nothing is known about whether this fly is itself associated with parasites or pathogens. In this study, diagnostic molecular methods indicated the presence …

Corporate Social Responsibility And Financial Performance Of U.S. Manufacturing And Service Small- And Medium-Sized Enterprises, Revlon Orlando Williams

Walden Dissertations and Doctoral Studies

Corporate social responsibility (CSR) investment strategies impact the business outcomes of firms of all sizes regardless of investment motives. But for small- and medium-sized enterprises (SME), the consequences of CSR investment are more immediate when compared to larger firms due to the condensed lag time between decisions and their respective outcomes. The purpose of this study was to determine whether the management decisions of social or environmental CSR investments for U.S.-based service and manufacturing SMEs are effective as represented by financial performance in their respective business sectors. The theoretical framework of this study was stakeholder and social capital theories. Five …

Climate Change Information's Impact On Death-Thought Accessibility And Global Climate Change Belief, Troy Class Franklin

Walden Dissertations and Doctoral Studies

Global climate change is perhaps the greatest current existential threat to life on this planet. Despite the overwhelming scientific consensus for the existence of human-made global climate change, climate change skepticism continues to be a significant obstacle. The purpose of this experimental online study was to address research questions concerning the effect of climate change information on death-thought accessibility (DTA) and belief in global climate change and to investigate whether a relationship exists between DTA and belief certainty in global climate change. Terror management theory was the theoretical foundation for the study. The study sample consisted of 104 participants randomly …

Association Between Maoa U Vntr Genetic Polymorphism And Aggression, Gender, And Race In Adolescents, Almaz Adair Johnson

Walden Dissertations and Doctoral Studies

A genetic polymorphism found in the upstream region of the monoamine oxidase A (MAOA) gene upstream variable number tandem repeat (u VNTR) has been shown to have an influence on aggression with mixed results. The purpose of this quantitative study was to examine the association between the u VNTR genetic polymorphism of the MAOA gene and aggression in an adolescent population 13–18 years of age. The conceptual framework was based on the biosocial model of antisocial behavior that indicates genes can influence aggressive behaviors with or without environmental influences. Data (N = 2506) from the National Longitudinal Adolescents and Adult …

Evaluation Of The Impact Of Virginia’S Senate Bill 1294 On Crisis Intervention Team Cooperation, Dennis Ray Martin

Walden Dissertations and Doctoral Studies

In 2009, the Commonwealth of Virginia passed Senate Bill (SB) 1294 that directly involved the Department of Criminal Justice Services and the Department of Behavioral Health and Developmental Services in the spread of the Crisis Intervention Team (CIT) program statewide. The purpose of this mixed-method study was to explore how the passage of SB 1294 affected the level of stakeholder cooperation within Virginia’s statewide CIT program, through 11 interviews with Virginian CIT leaders and by the completion of 115 questionnaires by CIT members in a region of central Virginia. Findings indicated the most common way that SB 1294 affected CIT …

Understanding A Transitional Educational Program For Students With Autism And Intellectual Disabilities, Robin E. Ruiz

Walden Dissertations and Doctoral Studies

The number of children in U.S. schools diagnosed with autism and intellectual disabilities disorders is increasing and they face low levels of employment after graduation. Without a viable education, including work skills training, these students cannot be successful citizens. The purpose of this generic qualitative study was to understand the experiences and perceptions of educators implementing an innovative transitional secondary education program designed to prepare students who have intellectual disabilities and autism to be successful in college or the workplace. The conceptual framework for this study included the theory of self-efficacy, sociocultural learning theory, differentiated instruction, and experiential learning theory. …

Impact Of Social Economic Factors On U. S. Veterans’ Access To Care, William Kwaku Adjei Ofori

Walden Dissertations and Doctoral Studies

Coronary heart disease (CHD), the leading cause of death worldwide, affects about 8.45 million United States veterans, individuals honorably discharged from the active military, naval services, and air services. The purpose of this study was to determine whether veterans’ access to care is associated with income level determinants, such as job status, education level, and location. Using the social cognitive theory as the framework, the study examined the extent to which income level and the other social determinants, impacted access to care for veterans with CHD. The 2016 Behavioral Risk Factor Surveillance System, the nation’s leading data system was the …

Untouchable, Michael Schreyach

Art and Art History Faculty Research

No abstract provided.

State Of Our Community: San Antonio Lgbtq+ 2020 Survey, Amy L. Stone, Robert Salcido Jr, Charlotte Georgiou, Ryann Williams

Sociology & Anthropology Faculty Research

In 2017, researchers, advocates, & community members formed the Strengthening Colors of Pride team & set out to understand the lived experiences of lesbian, gay, bisexual, transgender, queer, & other gender & sexual minority (LGBTQ+) people in the San Antonio Metro Area. Project leaders, with the help of a research team & community advisory board members, developed the largest survey of LGBTQ+ identified individuals ever conducted in South Texas. The survey provides important insight about the demographics of LGBTQ+ people in the area & their experiences with housing & homelessness, healthcare, employment, familial rejection & support, financial stability, resiliency, & …

A Leap Of Faith: Twail Meets Caribbean Queer Rights Jurisprudence—Intersections With International Human Rights Law, H. Patrick Wells

Dalhousie Law Journal

This article examines the legal status of queer rights in Caribbean jurisprudence. It conducts an analysis of Caribbean queer rights case law, in order to arrive at an understanding of the extent and dynamics of constitutional protection for these rights. It then uses the revelations from this analysis to determine how Caribbean queer rights jurisprudence has intersected with international human rights norms, values and rules. Finally, the article applies the TWAIL methodological approach to international law to argue that the Caribbean queer rights jurisprudence has not so far reflected the counter-hegemonic, resistance, anti-imperialist discourse that TWAIL champions, in spite of …

Methyl Ketones From Carboxylic Acids As Valuable Target Molecules In The Biorefinery, Olivier Marie, Alexey Ignatchenko, Michael Renz

Chemistry Faculty/Staff Publications

For the preparation of methyl ketones, cross Ketonic Decarboxylation, i.e., the formation of a ketone from two different carboxylic acids, and the reketonization, i.e., the transformation of a carboxylic acid into a ketone employing a ketone as alkyl transfer agent, may be interesting alternatives to classical pathways involving metal-organic reagents.

The fine chemical 2-undecanone was chosen as model compound and ketonic decarboxylation and reketonization evaluated by Green Chemistry matrices, namely the carbon atom efficiency and the e-factor. The e-factor of the reaction of decanoic acid with acetic acid was less than five and, therewith, in the acceptable range for bulk …

Noncontact Multiscale Diffuse Optical Imaging Of Deep Tissue Hemodynamics In Animals And Humans, Siavash Mazdeyasna

Theses and Dissertations--Biomedical Engineering

Blood flow (BF) impacts the delivery of oxygen and nutrients to tissues and the removal of metabolic byproducts from tissues. Imaging of BF distributions helps characterize many diseases associated with tissue hypoxia/ischemia. The purpose of this study was to develop and validate a novel, noninvasive, noncontact, high-density camera-based speckle contrast diffuse correlation tomography (scDCT) device for use in both animal and human studies. The scDCT uses a galvo-mirror to remotely deliver the focused point near-infrared light to source positions and a sensitive 2D camera to quantify spatial diffuse speckle fluctuations, resulting from the movement of red blood cells in deep …

Fluvial Sediment Organic Matter Degradation Identified With Elemental And Isotopic Fate During Laboratory Incubation, Brenden Riddle

Theses and Dissertations--Civil Engineering

Fluvial sediment is well recognized as a critical factor in both carbon and nutrient budgets within stream systems. However, we find very few studies of reactivity and isotope enrichment for stream water from agricultural and urban streams and the class of substrate known as fluvial sediment organic matter. This study investigated the hypothesis that fluvial sediment is subject to degradation even though many previous studies have considered this class of substrate generally inert. Therefore we qualify that elemental and isotopic signatures of fluvial sediment organic matter should be considered potentially non-conservative when used in tracer studies. Methods applied to this …

A Modeling Approach To Understanding Glyphosate Transport In The Belize River Watershed, Barbara Anmei Astmann

Theses and Dissertations--Civil Engineering

Glyphosate is the most widely used herbicide worldwide and is often transported from application areas to surface water when solubilized in runoff or sorbed to eroded sediment. There is evidence that suggests both glyphosate and its main metabolite aminomethylphosphonic acid (AMPA) may pose a risk to human health, as well as cause adverse effects in the environment. However, consistent monitoring data is still limited, especially in developing countries. Belize is a developing nation with agriculture being a major sector of its economy and is heavily reliant on glyphosate. The widespread use of glyphosate in Belize may be resulting in glyphosate …

Investigation Into The Presence, Persistence, And Fate Of S. Aureus, And Its Mobile Genetic Elements, In Wastewater And The Surrounding Environment, Atena Amirsoleimani

Theses and Dissertations--Civil Engineering

Currently, the world is engaged in a battle against very small parts of our environment that develop and share genes for resistance to multiple environmental conditions. Pathogenic infections caused by antibiotic-resistant bacteria have been impacting animal and human health and life. Increasing incidences of methicillin- resistant Staphylococcus aureus (MRSA) infections transmitted through the environment are rising faster than the discovery of new antibiotics. Multi-drug resistant S. aureus infections in healthy individuals without prior hospitalization have been increasing all around the world.

Many people carry S. aureus in their nose and on their skin, common niches for the bacteria to co-grow …

May Ayim's Blue Notes In Blues In Schwarz Weiss, Gabrielle Taylor

Theses and Dissertations--Modern and Classical Languages, Literature and Cultures

May Ayim has become a staple when it comes to Black German poetry within German Studies and continues to influence and challenge ideas of what it means to be black in Germany at the end of the 20th century. What is perhaps not challenged enough is the ways in which we, the readers and students of German literature and poetry, approach and study Ayim’s poetry as we move deeper into the 21st century. Her collection of poetry, Blues in Schwarz Weiss, can be seen through a significant word found in her collection’s title—blues. It is through blues, …

Landscape Ecology And Population Genomics Of Two Sympatric Pitviper Species Across A Fragmented Appalachian Landscape, Thomas Maigret

Theses and Dissertations--Biology

Understanding the link between landscape patterns and ecological and evolutionary processes is an important prerequisite for informed wildlife conservation and management, especially in rapidly changing landscapes. Until recently, the inaccessibility of spatial and genomic data sets of sufficient resolution limited our ability to incorporate the impacts of landscape patterns into predictions of ecological and environmental outcomes. In this dissertation, I utilized several high-resolution spatial and genomic data sets to address ecological questions in a rapidly fragmenting landscape in southeastern Kentucky. Overall, my results indicate that large-scale surface coal mining is causing widespread homogenization of landforms, resulting in a uniquely permanent …

Predicting Patterns Of Gene Family Evolution In Taxa With Similar Ecological Niches, Kim Vertacnik

Theses and Dissertations--Biology

To fully understand the genetic basis of adaptation, we need to know its predictability—the extent to which specific selective pressures and contexts can yield corresponding genetic changes. In particular, the repeated colonization of similar, specialized environments by different taxa is ideal for assessing the frequency of reoccurring changes in the same genes or functions. But compared to a growing body of literature on the convergent evolution of individual genes, far less is known about the repeatability of gene family evolution, where families (defined here as groups of genes that share sequence and functional similarity from common ancestry) can expand (gain …

The Role Of Melatonin In Biological Rhythms Of Songbirds, Clifford E. Harpole

Theses and Dissertations--Biology

In vertebrates, melatonin is a hormone that is produced and secreted at night and inhibited by light. This unique “darkness-only” expression profile makes it an intellectually appealing candidate for a means of transmitting temporal information to an individual, both time of day and time of year.

In passerine birds, “time of day” information is certainly transmitted via melatonin secretion. The primary producer of systemic melatonin in this family of birds is the pineal gland, and surgical removal of it causes a bird to become arrhythmic in constant conditions. I find that as pinealectomized house sparrows (Passer domesticus) become …

Investigation Into The Roles Of Her9 And Capn5 During Retinal Development And Regeneration, Cagney Coomer

Theses and Dissertations--Biology

The formation of a healthy and functioning eye requires coordinated interactions between numerous signaling pathways and gene regulatory networks within the developing neural retina. Tight regulation of gene expression is required for cell specification and differentiation in this multilayered, light sensitive tissue. The photoreceptors are the light detecting cells of the retina, capable of functioning in both intense sunlight and dim light at night. When pigment cells of the photoreceptor outer segment are activated by light, a complex chain of events called phototransduction leads to the electrical signal cascade that is transmitted through the retina and ultimately to the brain …

Limb Development In Salamanders: An Evolutionary Perspective To The Tetrapod Limb, Sruthi Purushothaman

Theses and Dissertations--Biology

Vertebrate limb is an ideal model to study growth, patterning and morphogenesis and the interplay between these processes. The developing limb bud is a three-dimensional structure and its outgrowth depends on the interaction between 2 important signaling centers: the Apical Ectodermal Ridge (AER) at the junction of the dorsal and ventral halves of the limb bud and the Zone of Polarizing activity (ZPA) in the posterior mesenchyme. These centers produce their respective key molecules and the close interplay between them specifies structures along the anterior-posterior (thumb to pinky), proximal-distal (shoulder to fingertips) and dorsal-ventral (knuckle to palm) axes.

Developmental biologists …

Becoming Gentrifier/D: Aesthetics, Subjectivities, And Rhythms Of Gentrification In Seoul, South Korea, Myung In Ji

Theses and Dissertations--Geography

Gentrification has been extensively studied beyond Euro-American societies. In particular, previous research of Seoul’s residential gentrification has broadened our understanding of the role of the developmental state and property speculation in urban clearance and renewal. However, little attention has been paid to the contemporary retail gentrification in Seoul that has different aesthetics, subjectivities, and rhythms compared to residential gentrification. In retail gentrification, old urban neighborhoods are no longer demolished but cherished with their nostalgic landscapes and atmospheres. In this context, this dissertation project explores Seochon, a gentrifying neighborhood in Seoul, that was designated as a cultural heritage site in 2010. …

Reserved For The Whole Earth: Forms Of Evidence, Ought Anxiety, And The Futures Of Geographic Inquiry, Eric M. Robsky Huntley

Theses and Dissertations--Geography

This dissertation examines geographic forms of evidence in the practices of landscape architects and geographers. I analyze evidence not only as an epistemic phenomenon, but as an aesthetic one, as well. Convincing an audience that the world is (or should be) one way and not another requires that knowledges be stacked, extended, and stitched together in a manner admissable to an audience. In the first two chapters, I use the case of the landscape architect Ian McHarg to examine how his approach to integrating scientific knowledge---a aesthetic response to what I theorize as 'ought anxiety'---grew alongside the environmental bureaucracy in …