Digital Commons Network^™

On The Interior Design Of Healthcare Environments, Liam Owens

Renée Crown University Honors Thesis Projects - All

No abstract provided.

Characterization Of Seizure Threshold In System Xc- Astrocyte-Conditional Null Mice, Myles Morgan

Renée Crown University Honors Thesis Projects - All

No abstract provided.

Nature Does It Better: Biomimicry In Structural And Architectural Design, Michael Yacubov

Renée Crown University Honors Thesis Projects - All

No abstract provided.

Examining The Wealth Trends In Kombewa, Kenya, Alizee Mclorg

Renée Crown University Honors Thesis Projects - All

No abstract provided.

Repetitive Behavior In Maternally Separated Cd-1 Mice, Sarina Wallace

Renée Crown University Honors Thesis Projects - All

No abstract provided.

Philippe And The Syracuse State School: Psychiatry And The Moral Treatment In France And The United States, 1750-1850, Taylor Mckinney

Renée Crown University Honors Thesis Projects - All

No abstract provided.

Counterculture Dystopia: A Comparative Study Of The Rajneesh-Osho Movement And The Counterculture, Junjie Ren

Renée Crown University Honors Thesis Projects - All

No abstract provided.

Controlled Substance Regulation For The Covid-19 Mental Health Crisis, Mason Marks

Scholarly Publications

The COVID-19 pandemic is producing widespread loss of life, unemployment, and social isolation that is triggering a mental health crisis. Experts warn there could be record levels of depression, suicide, and substance use disorders. The U.S. healthcare system is not prepared. It lacks the resources to provide prolonged psychotherapy at scale, and existing drug treatments are ineffective in about half the people who ty them. Amid worsening mental health-related morbidiy and mortaliy, the experimental drugs psilocybin and 3,4- Methylenedioxymethamphetamine (MDMA) are an untapped resource. These drugs belong to a class of compounds called the psychedelics, which has been criminalized and …

Leaders Are Not Fiduciaries, Kelli Alces Williams

Scholarly Publications

Leaders have long been described as fiduciaries because they are entrusted with the power to make decisions that significantly affect the lives and welfare of others. While trustworthiness is an admirable and necessary quality in a leader, fiduciary doctrine describes neither the bounds of a leader's behavior nor the protections enjoyed by the governed Fiduciary doctrine does not occupy the field of trusting relationships. Leaders sell both the goals and priorities thy will pursue in their positions and their own trustworthiness - that is, the combination of ability, integrity, and benevolence they bring to the task. In order to win …

Intraspecific Aggression Towards Common Bottlenose Dolphin Calves, Northern Gulf Of Mexico, Errol Ronje, Sarah Piwetz, Heidi Whitehead, Keith D. Mullin

Gulf and Caribbean Research

Infanticide has been widely documented throughout the animal kingdom, and has generally been viewed as an evolved, or adaptive behavior for the perpetrators. Infanticide motivated by increased sexual access to females with calves, or the elimination of potential genetic competition in the form of calf-directed aggression or infanticide, has been proposed for delphinids including killer whales, Indo-Pacific humpback dolphins, Guiana dolphins, and bottlenose dolphins. However, reports of intraspecific aggression towards bottlenose dolphin calves are relatively infrequent, and accounts of confirmed infanticide are rarer still. Reporting instances of intraspecific calf-directed aggression aids researchers to better understand the socio-behavioral context of these …

Nursery Exposure Of Oyster Spat To Different Predators Strengthens Oyster Shells, Melanie Ponce, Benjamin Belgrad, William Walton, Lee Smee

Gulf and Caribbean Research

No abstract provided.

Essential Oils Of Tagetes Minuta And Tithonia Diversifolia Affect Host Location Behaviour And On-Host Attachment Site Preference Of The Brown Ear Tick, Rhipicephalus Appendiculatus In The Semi-Field Studies, Wycliffe Wanzala, Ahmed Hassanali, Wolfgang Richard Mukabana, Willem Takken, Sheila Iminza Minyoso

All Peer-Reviewed Publications

Effects of essential oils of Tagetes minuta and Tithonia diversifolia (Asteraceae) on orientation behaviour and on-host attachment site preference of newly hatched adult Rhipicephalus appendiculatus were evaluated. Host animals were treated at the ear pinna (by smearing the oil directly on the ear or suspending a tube containing the oil on the ear pinna) and legs + tail in semi-field plots. The legs + tail sites of the essential oil application showed the lowest mean percentage of ticks observed on host body (16.5 ± 1.9% and 26.0 ± 2.8%) and the highest mean percentage reduction of attaching ticks (76.5 ± …

Mineral Fertilizer Use In Land-Scarce Conditions: Case Of Rwanda, Josaphat Rusisiro Mugabo, Eric Tollens, Jonas Nwankwo Chianu, Bernard Vanlauwe

All Peer-Reviewed Publications

This study was undertaken to investigate the use of mineral fertilizer by smallholder farmers in order to understand the set of factors influencing the decisions of smallholder farmers to use fertilizers in land-scarce conditions. Using descriptive analysis and the Cragg's double-hurdle model, the study identified and analyzed factors that determine smallholder farmer adoption of mineral fertilizers and those that affect the intensity of household mineral fertilizer use. From factors that only influence the decision of smallholder farmers to use mineral fertilizers, distance to fertilizer market and livestock affects it negatively; while farmer association membership, landholding per capita, access to extension …

The Greater Yellowstone Ecosystem Revisited: Law, Science, And The Pursuit Of Ecosystem Management In An Iconic Landscape, Robert B. Keiter

University of Colorado Law Review

Thirty years ago, the Greater Yellowstone Ecosystem (GYE) concept and ecosystem management surfaced as key to preserving this legally fragmented region's public lands and wildlife in the face of mounting development pressures. Yellowstone's grizzly bears were in sharp decline and wolves were absent from the landscape, while bison and elk management issues festered. The GYE's national forest lands were subject to extensive logging, energy leasing, and other commercial activities that cumulatively threatened the region's ecological integrity. In the face of extreme jurisdictional complexity and a strong commitment to agency discretion, a high-profile federal "Vision" effort to improve and better coordinate …

Seed Quality And Mycoflora Associated With Chickpea (Cicer Arientinum L.) Seed In Ethiopia, G. Getaneh, T. Tefera, F. Lemmessa, S. Ahmed, A. Zewudie

All Peer-Reviewed Publications

The study was conducted at Ethiopian Institute of Agricultural Research, Haramaya University and Jimma University, Ethiopia. Crop yield is directly associated with the physical and biological quality of planting material or seed. Ninety-nine (99) chickpea seed lot samples were collected for physical purity, seed health and germination tests from major chickpea growing areas in Ethiopia in the 2016/17 cropping season to assess the status of chickpea seed health and quality among subsistence farmers, research stations and seed growers. The seed lots were grouped as researcher saved, farmers saved and seed growers’ saved seed. The maximum physical purity of 97.5% was …

Population Genetics Of The Mediterranean Corn Borer (Sesamia Nonagrioides) Differs Between Wild And Cultivated Plants, Abdel Kader Naino Jika, B. Le Ru, C. Capdevielle-Dulac, F. Chardonnet, J. F. Silvain, L. Kaiser, S. Dupas

All Peer-Reviewed Publications

The population genetic structure of crop pest populations gives information about their spatial ecology, which helps in designing management strategies. In this paper, we investigated the genetic structure of the Mediterranean Corn Borer (MCB), Sesamia nonagrioides Lefèbvre (Lepidoptera: Noctuidae), one of the most important maize pests in the Mediterranean countries, using microsatellite markers for the first time in this species. Insects were collected in twenty-five locations in southwest and southeast France from cultivated and wild host plants (Zea mays, Sorghum halepense and Typha domingensis). Contrary to what has been reported so far in France, we found that MCB populations could …

Cooley’S Constitutional Limitations And Constitutional Originalism, Lawrence B. Solum

Faculty Scholarship

Thomas Cooley’s A Treatise on The Constitutional Limitations Which Rest upon the Legislative Power of the States of the American Union was the most influential treatise of constitutional law in the second half of the nineteenth century. This Essay explores the ideas expressed in Cooley’s treatise in light of contemporary originalist constitutional theory. In many ways, Constitutional Limitations anticipated some of the key moves made by contemporary public meaning originalists, including the interpretation-construction distinction and the idea that ordinary meaning, and not technical meaning, is the baseline for constitutional interpretation.

A Relational Analysis Of Enterprise Obligations And Carbon Majors For Climate Justice, Sara L. Seck

Articles, Book Chapters, & Popular Press

A coherent theory of climate justice must answer the question of “who owes what to whom, and why?” In this paper I consider this question with a focus on the contribution of business enterprises, in particular the ‘carbon majors’, to climate injustice. I will first introduce a relational approach to legal analysis, drawing upon the work of feminist and vulnerability theorists, Indigenous feminist theorists, and feminist corporate and international law theorists. This relational approach confronts the dominant yet unacknowledged prevalence of the bounded autonomous individual of liberal thought in diverse areas of law and policy, and offers a method not …

Searching For “Superchief” And Other Fictional Indians: A Narrative And Case Comment On R V Bernard, Naiomi Metallic

Articles, Book Chapters, & Popular Press

In R v Bernard, 2017 NBCA 48, the New Brunswick Court of Appeal upheld the lower courts’ reasoning that a Mìgmaw man living in the traditional Mìgmaq hunting territory of St. John, New Brunswick could not exercise his Aboriginal rights to hunt because he could not prove he descended from the particular subgroup of Mìgmaq who were at St. John at the time of contact with Europeans. In deciding so, the Court of Appeal rejected the argument that the Mìgmaq, as a nation, are the appropriate rights holders and ought to be the body deciding who can exercise the Mìgmaw …

Symposium Introduction: Teaching And Researching International Law – Global Perspectives, James Thuo Gathii, Olabisi D. Akinkugbe, Nthope Mapefane, Titilayo Adebola, Ohio Omiunu

Articles, Book Chapters, & Popular Press

Welcome to the Teaching and Researching International Law – Global Perspectives Symposium. This series of blog posts gathers perspectives from international law teachers, researchers and students from different regions and all stages of their careers and legal education, to reflect together on common challenges and imagined futures of our profession. This Symposium is held in a moment of great uncertainty – but also of possibility: the Critical Pedagogy Symposium recently held on Opinio Juris offered thought-provoking commentary from across the globe on critical international pedagogy and the virtual space, while the forthcoming TWAILR series on Critique and the Canon promises …

Covid-19 Vaccines As Global Public Goods, Jason W. Nickerson, Matthew Herder

Articles, Book Chapters, & Popular Press

Vulnerable: The Law, Policy and Ethics of COVID-19 confronts the vulnerabilities that have been revealed by the pandemic and its consequences. It examines vulnerabilities for people who have been harmed or will be harmed by the virus directly and those harmed by measures taken to slow its relentless march; vulnerabilities exposed in our institutions, governance, and legal structures; and vulnerabilities in other countries and at the global level where persistent injustices affect us all. COVID-19 has forced us to not only reflect on how we govern and how we set policy priorities, but also to ensure that pandemic preparedness, precautions, …

Introduction, Aldo Chircop, Floris Goerlandt, Claudio Aporta, Ronald Pelot

Articles, Book Chapters, & Popular Press

This chapter introduces a multidisciplinary collection of chapters addressing various aspects of governance of Arctic shipping written by leading international scholars. It investigates how ocean changes and anthropogenic impacts affect our understanding of risk, policy, management and regulation for safe navigation, environment protection, conflict management between ocean uses, and protection of Indigenous peoples’ interests in Canadian Arctic waters. The book is divided in three parts, together providing a multi-faceted and interdisciplinary view on governance of Arctic shipping. The first part addresses conceptual and empirical aspects of risk governance, management, and assessment in the Canadian Arctic. The second part focuses on …

The Regulation Of Heavy Fuel Oil In Arctic Shipping: Interests, Measures, And Impacts, Jiayu Bai, Aldo Chircop

Articles, Book Chapters, & Popular Press

Since the International Maritime Organization’s (IMO) ban on the use and carriage for use of heavy fuel oil (HFO) for ships operating in Antarctic waters came into effect in 2011, the international community has been engaged in a discourse on whether to adopt a similar standard for ships operating in Arctic waters. The issues are complex as, in addition to reducing the environmental risks posed by HFOs, there are economic and social consequences, including dependence on such fuels by Indigenous peoples. The discourse has involved the IMO, the Arctic Council, industry associations, environmental nongovernmental organizations, and Indigenous peoples. The issue …

The Regulation Of Ship Emissions In Canadian Northwest Atlantic And Arctic Waters: Is There A Need For Consistency And Equity?, Aldo Chircop

Articles, Book Chapters, & Popular Press

Since the adoption of Annex VI of the International Convention on the Prevention of Pollution from Ships, 1973/78, the International Maritime Organization has gradually expanded the scope of ship emission regulation to include VOCs, SOx, NOx, particulate matter and, more recently, greenhouse gas emissions. This regulatory effort has not been integrated and displays some inconsistency and even fragmentation, resulting in different levels of environment protection for different regions and even potential conflicts between standards. The regulation of use and carriage of heavy sulphur fuel oil may lead to increase of clean fuel use and thereby produce more CO2 emissions. Designation …

Route Exploration And Synthesis Of The Reported Pyridone-Based Pdi Inhibitor Stk076545, Eric Greve, Sergey V. Lindeman, Christina Scartelli, Lin Lin, Robert Flaumenhaft, Chris Dockendorff

Chemistry Faculty Research and Publications

The enzyme protein disulfide isomerase (PDI) is essential for the correct folding of proteins and the activation of certain cell surface receptors, and is a promising target for the treatment of cancer and thrombotic conditions. A previous high-throughput screen identified the commercial compound STK076545 as a promising PDI inhibitor. To confirm its activity and support further biological studies, a resynthesis was pursued of the reported β-keto-amide with an N-alkylated pyridone at the α-position. Numerous conventional approaches were complicated by undesired fragmentations or rearrangements. However, a successful 5-step synthetic route was achieved using an aldol reaction with an α-pyridone allyl …

What Is The Effect Of Social Capital On Community Resiliency Against Social Decay?, James Dail

CMC Senior Theses

This thesis builds off of the work of Robert Putnam and Charles Murray by using a fixed effects regression model and a first difference regression model to see if there is a relationship between the number of community institutions within a county and that county’s resiliency against social decay. Historically, it has been difficult to determine if there is a causal relationship in either direction between these variables because they are endogenous. That is, the underlying factors that determine whether a county will have low levels of social capital also determine whether the same county will have high levels of …

Antifungal Defense Molecules From Bacterial Symbionts Of North American Trachymyrmex Ants, Georgia Scherer

CMC Senior Theses

Defensive symbioses, in which microbes provide molecular defenses for an animal host, hold great potential as untapped sources of therapeutically useful antibiotics. Fungus-growing ants use antifungal defenses from bacterial symbionts to suppress pathogenic fungi in their nests. Preliminary chemical investigations of symbiotic bacteria from this large family of ants have uncovered novel antifungal molecules with therapeutic potential, such as dentigerumycin and selvamicin.

In this study, the bacterial symbionts of North American Trachymyrmex fungus-growing ants are investigated for antifungal molecules. Plate-based bioassays using ecologically-relevant fungal pathogens confirmed that these bacteria have antifungal activity. In order to purify and identify the antifungal …

Examining Protein-Protein Interactions Within The Esx-4 Secretion System Of Mycobacterium Smegmatis, Sophie Boerboom

CMC Senior Theses

Bacteria use secretion systems to export proteins from inside of the bacterium into the periplasm, extracellular space, or host cell. Within the Mycobacterium genus, the type VII secretion systems (T7SS) transport products across the unusually thick and waxy mycobacterial envelope. T7SS are of particular importance because they are involved in the virulence of pathogenic mycobacteria. Mycobacteria have as many as five distinct T7SS called ESX systems. ESX-1, 3, and 5, have demonstrated roles in viability and virulence in certain pathogenic species like M. tuberculosis and M. marinum. Our research focuses on the ESX-4 apparatus, the ancestral system that gave rise …

Effects Of Sleep Deprivation And The Link To Alzheimer’S Disease In Night Shift Workers, Aracelia Aldrete

CMC Senior Theses

Alzheimer’s Disease (AD) is a degenerative neurologic disorder that is often defined by beta-amyloid (Aβ) plaques. These Aβ plaques are formed from protein pieces that are incorrectly cleaved from an amyloid precursor protein (APP). These protein segments, cleaved from APP, are toxic due to increased “stickiness”. They cling together to create protofibrils that eventually mature into neuronal plaques. Aβ plaques lead to neuronal cell death causing classic AD symptoms: memory loss, a decline in speech and motor control, and personality changes. One connection between high Aβ plaques levels and AD is chronic sleep loss or disruption. Night shift workers, even …

The Necessity For Sustainable Development In Indonesia: A Governmental Analysis And Carbon Neutral Coliving Recommendation, Michael Wirth

CMC Senior Theses

This thesis explores two distinct topics: first, Indonesia’s current emissions and implementation of sustainability practices; second, the current state of coliving spaces and a proposal of a sustainable space in Indonesia,. The two topics are connected by the fact that the implementation of sustainability practices within Indonesia are necessary from more than just an environmental standpoint, but also from the economic and governmental perspectives.

We exemplify the necessity for sustainable transition within the country through three critical points: first, we show that Indonesia’s exceptional tourist growth is highly dependent on sustaining the natural wonders within the country; second, current coal …