Digital Commons Network^™

Getting Published In Sotl, Emily Faulconer

Publications

Navigating the publication process can be confusing and frustrating if you don't know what to expect. This session will outline and discuss successful approaches from manuscript generation to post-publication promotion of your work.

We will explore how to identify potential dissemination venues, factors to consider when vetting a journal (readership, impact, access, etc.), editorial processes, and how to strategically get your message across to editors and viewers. From search engine optimization to graphical abstracts and social media, what steps can you take the get the most out of your publication? How can you navigate the "failure points" (growth opportunities) in …

Qcm Sensor Arrays, Electroanalytical Techniques And Nir Spectroscopy Coupled To Multivariate Analysis For Quality Assessment Of Food Products, Raw Materials, Ingredients And Foodborne Pathogen Detection: Challenges And Breakthroughs†, David K. Bwambok, Noureen Siraj, Samantha Macchi, Nathaniel E. Larm, Gary A. Baker, Rocío L. Pérez, Caitlan E. Ayala, Charuksha Walgama, David Pollard, Jason D. Rodriguez, Souvik Banerjee, Brianda Elzey, Isiah M. Warner, Sayo O. Fakayode

Faculty Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Quality checks, assessments, and the assurance of food products, raw materials, and food ingredients is critically important to ensure the safeguard of foods of high quality for safety and public health. Nevertheless, quality checks, assessments, and the assurance of food products along distribution and supply chains is impacted by various challenges. For instance, the development of portable, sensitive, low-cost, and robust instrumentation that is capable of real-time, accurate, and sensitive analysis, quality checks, assessments, and the assurance of food products in the field and/or in the production line in a food …

The Effect Of Summer Drought On The Predictability Of Local Extinctions In A Butterfly Metapopulation, Erik Van Bergen, Tad Dallas, Michelle F. Dileo, Aapo Kahilainen, Anniina L.K. Mattila, Miska Luoto, Marjo Saastamoinen

Faculty Publications

© 2020 The Authors. Conservation Biology published by Wiley Periodicals LLC on behalf of Society for Conservation Biology The ecological impacts of extreme climatic events on population dynamics and community composition are profound and predominantly negative. Using extensive data of an ecological model system, we tested whether predictions from ecological models remain robust when environmental conditions are outside the bounds of observation. We observed a 10-fold demographic decline of the Glanville fritillary butterfly (Melitaea cinxia) metapopulation on the Åland islands, Finland in the summer of 2018 and used climatic and satellite data to demonstrate that this year was an anomaly …

Two Hundred And Fifty-Four Metagenome-Assembled Bacterial Genomes From The Bank Vole Gut Microbiota, Anton Lavrinienko, Eugene Tukalenko, Timothy A. Mousseau, Luke R. Thompson, Rob Knight, Tapio Mappes, Phillip C. Watts

Faculty Publications

Vertebrate gut microbiota provide many essential services to their host. To better understand the diversity of such services provided by gut microbiota in wild rodents, we assembled metagenome shotgun sequence data from a small mammal, the bank vole Myodes glareolus (Rodentia, Cricetidae). We were able to identify 254 metagenome assembled genomes (MAGs) that were at least 50% (n = 133 MAGs), 80% (n = 77 MAGs) or 95% (n = 44 MAGs) complete. As typical for a rodent gut microbiota, these MAGs are dominated by taxa assigned to the phyla Bacteroidetes (n = 132 MAGs) and …

17Β-Estradiol Promotes Acute Refeeding In Hungry Mice Via Membrane-Initiated Erα Signaling, Kaifan Yu, Yanlin He, Ilirjana Hyseni, Zhou Pei, Yongjie Yang, Pingwen Xu, Xing Cai, Hesong Liu, Na Qu, Hailan Liu, Yang He, Meng Yu, Chen Liang, Tingting Yang, Julia Wang, Pierre Gourdy, Jean Francois Arnal, Francoise Lenfant, Yong Xu, Chunmei Wang

Division of Basic Science Faculty Publications

Objective: Estrogen protects animals from obesity through estrogen receptor α (ERα), partially by inhibiting overeating in animals fed ad libitum. However, the effects of estrogen on feeding behavior in hungry animals remain unclear. In this study, we examined the roles of 17β-estradiol (E2) and ERα in the regulation of feeding in hungry female animals and explored the underlying mechanisms. Methods: Wild-type female mice with surgical depletion of endogenous estrogens were used to examine the effects of E2 supplementation on acute refeeding behavior after starvation. ERα-C451A mutant mice deficient in membrane-bound ERα activity and ERα-AF20 mutant mice lacking ERα transcriptional activity …

Estrogen Receptor-Α Expressing Neurons In The Ventrolateral Vmh Regulate Glucose Balance, Yanlin He, Pingwen Xu, Chunmei Wang, Yan Xia, Meng Yu, Yongjie Yang, Kaifan Yu, Xing Cai, Na Qu, Kenji Saito, Julia Wang, Ilirjana Hyseni, Matthew Robertson, Badrajee Piyarathna, Min Gao, Sohaib A. Khan, Feng Liu, Rui Chen, Cristian Coarfa, Zhongming Zhao, Qingchun Tong, Zheng Sun, Yong Xu

Division of Basic Science Faculty Publications

Brain glucose-sensing neurons detect glucose fluctuations and prevent severe hypoglycemia, but mechanisms mediating functions of these glucose-sensing neurons are unclear. Here we report that estrogen receptor-α (ERα)-expressing neurons in the ventrolateral subdivision of the ventromedial hypothalamic nucleus (vlVMH) can sense glucose fluctuations, being glucose-inhibited neurons (GI-ERαvlVMH) or glucose-excited neurons (GE-ERαvlVMH). Hypoglycemia activates GI-ERαvlVMH neurons via the anoctamin 4 channel, and inhibits GE-ERαvlVMH neurons through opening the ATP-sensitive potassium channel. Further, we show that GI-ERαvlVMH neurons preferentially project to the medioposterior arcuate nucleus of the hypothalamus (mpARH) and GE-ERαvlVMH neurons preferentially project to the dorsal Raphe nuclei (DRN). Activation of ERαvlVMH …

Estrogen-Sensitive Medial Preoptic Area Neurons Coordinate Torpor In Mice, Zhi Zhang, Fernando M.C.V. Reis, Yanlin He, Jae W. Park, Johnathon R. Divittorio, Nilla Sivakumar, J. Edward Van Veen, Sandra Maesta-Pereira, Michael Shum, India Nichols, Megan G. Massa, Shawn Anderson, Ketema Paul, Marc Liesa, Olujimi A. Ajijola, Yong Xu, Avishek Adhikari, Stephanie M. Correa

Division of Basic Science Faculty Publications

Homeotherms maintain a stable internal body temperature despite changing environments. During energy deficiency, some species can cease to defend their body temperature and enter a hypothermic and hypometabolic state known as torpor. Recent advances have revealed the medial preoptic area (MPA) as a key site for the regulation of torpor in mice. The MPA is estrogen-sensitive and estrogens also have potent effects on both temperature and metabolism. Here, we demonstrate that estrogen-sensitive neurons in the MPA can coordinate hypothermia and hypometabolism in mice. Selectively activating estrogen-sensitive MPA neurons was sufficient to drive a coordinated depression of metabolic rate and body …

Genetic Determinants For Agronomic And Yield-Related Traits Localized On A Gbs-Snp Linkage Map From A Japonica X Indica Cross In Rice, Teresa B. De Leon, Rajat Pruthi, Babitha Jampala, Anna H. Borjas, Prasanta K. Subudhi

Faculty Publications

Rice is an important cereal for human consumption. Identification of QTLs for important agronomic traits with high resolution is essential to the identification of genes and marker-assisted breeding to improve rice productivity. A genotyping by sequencing (GBS)-based high-resolution SNP linkage developed in a recombinant inbred lines (RIL) population of a japonica (Bengal) × indica (Pokkali) cross was used for QTL analysis of traits such as days to heading, plant height, panicle length, flag leaf length, 1000 kernel weight, number of unfilled grains, number of filled grains, grain width, grain length, and awns using interval mapping and inclusive composite interval mapping …

Zinc Finger Transcription Factor Zbtb16 Coordinates The Response To Energy Deficit In The Mouse Hypothalamus, Helia Cheng, Schuyler J. Pablico, Jisu Lee, Ji Suk Chang, Sangho Yu

Division of Basic Science Faculty Publications

The central nervous system controls feeding behavior and energy expenditure in response to various internal and external stimuli to maintain energy balance. Here we report that the newly identified transcription factor zinc finger and BTB domain containing 16 (Zbtb16) is induced by energy deficit in the paraventricular (PVH) and arcuate (ARC) nuclei of the hypothalamus via glucocorticoid (GC) signaling. In the PVH, Zbtb16 is expressed in the anterior half of the PVH and co-expressed with many neuronal markers such as corticotropin-releasing hormone (Crh), thyrotropin-releasing hormone (Trh), oxytocin (Oxt), arginine vasopressin (Avp), and nitric oxide synthase 1 (Nos1). Knockdown (KD) of …

Sleep Extension: A Potential Target For Obesity Treatment, Kristin K. Hoddy, Kaitlin S. Potts, Lydia A. Bazzano, John P. Kirwan

Division of Basic Science Faculty Publications

Purpose of Review: Sleep and obesity share a bidirectional relationship, and weight loss has been shown to enhance sleep. Aiming to extend sleep on its own or as part of a lifestyle intervention may attenuate health consequences of short sleep. This review highlights several sleep extension approaches, discusses feasibility of each, and summarizes findings relevant to obesity. Recent Findings: Sleep extension in response to experimental sleep restriction demonstrates partial rescue of cardiometabolic dysfunction in some but not all studies. Adequate sleep on a nightly basis may be necessary for optimal health. While initial sleep extension interventions in habitually short sleepers …

Chronic Intermittent Hypoxia Triggers A Senescence-Like Phenotype In Human White Preadipocytes, Katarzyna Polonis, Christiane Becari, C. Anwar A. Chahal, Yuebo Zhang, Alina M. Allen, Todd A. Kellogg, Virend K. Somers, Prachi Singh

Clinical Research Faculty Publications

Obstructive sleep apnea (OSA) is a common sleep disorder associated with obesity. Emerging evidence suggest that OSA increases the risk of cardiovascular morbidity and mortality partly via accelerating the process of cellular aging. Thus, we sought to examine the effects of intermittent hypoxia (IH), a hallmark of OSA, on senescence in human white preadipocytes. We demonstrate that chronic IH is associated with an increased generation of mitochondrial reactive oxygen species along with increased prevalence of cells with nuclear localization of γH2AX & p16. A higher prevalence of cells positive for senescence-associated β-galactosidase activity was also evident with chronic IH exposure. …

Spread Of Pathological Tau Proteins Through Communicating Neurons In Human Alzheimer's Disease, Jacob W. Vogel, Yasser Iturria-Medina, Olof T. Strandberg, Ruben Smith, Elizabeth Levitis, Alan C. Evans, Oskar Hansson, Michael Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Enchi Liu, Tom Montine, Ronald G. Thomas, Michael Donohue, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Gus Jiminez, Danielle Harvey, Matthew Bernstein, Nick Fox, Paul Thompson, Norbert Schuff, Charles Decarli

Clinical Research Faculty Publications

Tau is a hallmark pathology of Alzheimer’s disease, and animal models have suggested that tau spreads from cell to cell through neuronal connections, facilitated by β-amyloid (Aβ). We test this hypothesis in humans using an epidemic spreading model (ESM) to simulate tau spread, and compare these simulations to observed patterns measured using tau-PET in 312 individuals along Alzheimer’s disease continuum. Up to 70% of the variance in the overall spatial pattern of tau can be explained by our model. Surprisingly, the ESM predicts the spatial patterns of tau irrespective of whether brain Aβ is present, but regions with greater Aβ …

Fam222a Encodes A Protein Which Accumulates In Plaques In Alzheimer’S Disease, Tingxiang Yan, Jingjing Liang, Ju Gao, Luwen Wang, Hisashi Fujioka, Michael W. Weiner, Norbert Schuff, Howard J. Rosen, Bruce L. Miller, David Perry, Paul Aisen, Paul Aisen, Arthur W. Toga, Gustavo Jimenez, Michael Donohue, Devon Gessert, Kelly Harless, Jennifer Salazar, Yuliana Cabrera, Sarah Walter, Lindsey Hergesheimer, Karen Crawford, Scott Neu, Lon S. Schneider, Sonia Pawluczyk, Mauricio Becerra, Liberty Teodoro, Bryan M. Spann, Ronald Petersen, Clifford R. Jack, Matthew Bernstein, Bret Borowski, Jeff Gunter, Matt Senjem

Clinical Research Faculty Publications

Alzheimer’s disease (AD) is characterized by amyloid plaques and progressive cerebral atrophy. Here, we report FAM222A as a putative brain atrophy susceptibility gene. Our cross-phenotype association analysis of imaging genetics indicates a potential link between FAM222A and AD-related regional brain atrophy. The protein encoded by FAM222A is predominantly expressed in the CNS and is increased in brains of patients with AD and in an AD mouse model. It accumulates within amyloid deposits, physically interacts with amyloid-β (Aβ) via its N-terminal Aβ binding domain, and facilitates Aβ aggregation. Intracerebroventricular infusion or forced expression of this protein exacerbates neuroinflammation and cognitive dysfunction …

66/2 | Jerusalem: Excavations In The Tyropoeon Valley (Givati Parking Lot) Volume Ii The Byzantine And Early Islamic Periods Part 2: Strata Iv–I:The Early Islamic Period, Doron Ben-Ami, Yana Tchekhanovets

IAA Reports—Monograph Series of the Israel Antiquities Authority

This volume is the second in a series of final reports presenting the results of the excavations conducted in the Givati Parking Lot, located on the eastern slope of the Tyropoeon Valley in Jerusalem. The site covers an area of c. 0.5 hectares, making it one of the largest excavations in the City of David. This second volume is comprised of three parts, and presents the remains of the Byzantine and Early Islamic periods. The exposure of Byzantine and Early Islamic remains over an extensive area has enabled a reassessment of the nature of the transition between these two periods, …

Assessment Of Dopaminergic And Serotonergic Receptor Antagonists In Male Rats Trained To Discriminate 4-Methylmethcathinone (Mephedrone), Rachel L. Burroughs

Masters Theses

Preclinical drug discrimination studies of the synthetic cathinone, 4-methylmethcathinone (mephedrone) have demonstrated its effects are comparable to those of other popular psychostimulant drugs. Few studies have directly examined the contribution of specific neurotransmitter receptors to mephedrone’s discriminative stimulus effects. The present study investigated the role of dopamine and serotonin receptors in these effects. Eight adult male Sprague-Dawley rats were trained to discriminate 3.0 mg/kg mephedrone from saline. After dose-response curves were determined with mephedrone (0.375-3.0 mg/kg), a series of stimulus antagonism tests were conducted with dopamine antagonists (Sch 23390, haloperidol) and serotonin antagonists (WAY 100,635, MDL 100,907, pirenperone) administered as …

Detecting Snake Fungal Disease (Ophidiomyces Ophiodiicola) In The Lower Rio Grande Valley, Manuel Zavala

Theses and Dissertations

Emerging diseases such as Snake Fungal Disease (SFD) caused by the fungus Ophidiomyces ophiodiicola (Oo) have caused population declines in various snake species in the United States which play a crucial role in the ecosystem as a natural pest control. This fungus targets the scales as a medium to thrive on which can lead to facial disfiguration and respiratory infections. We examined snakes to see if SFD was present in the LRGV and if other fungal species pose a threat to the various snake species population. The data for this study consisted of 14 live snakes captured in …

Investigation Of Sulfur Cycling In Marine Sponge Cinachyrella Spp. From A South Florida Reef, Shelby K. Cain

All HCAS Student Capstones, Theses, and Dissertations

Symbionts within marine sponges are actively participating in the biogeochemical cycles. Among them, the role of symbiont microbes in the sulfur cycle remains a mystery. This study measured the abundance of microbes within the genus Cinachyrella before and after exposure to hydrogen sulfide. A four-part study was conducted: a) five-hour drop experiments, b) vertical distribution experiments, c) five-hour uptake experiments, and d) long-term exposure experiments. The five-hour drop experiment utilized a microsensor to measure sulfide levels, which was lowered 1.0 mm every thirty minutes for a total of 5 hours. Three trials were performed, each with one sponge and a …

Atherosclerosis: Pathology, Role Of Sd-Ldl, Particle Size Characterization Of Sd-Ldl With Multiangle Light Scattering, Akshay Sudhakar Ukey

Masters Theses

Atherosclerosis is an inflammatory disease due to the accumulation of lipids in the inner wall of arteries. As per the report of Center of Diseases Control and Prevention (CDC), 1 in every 4 deaths is due to heart diseases each year. Atherosclerosis occurs when artery walls harden by the buildup of cholesterol, forming multiple atherosclerotic plaques within the aorta (4). Out of the modern medicines available to control cholesterol, statin is amongst the foremost widely used because it is both safe and effective in lowering high risk patients (9). However, usage of high statins dosage typically leads to some mild …

"Through A Forest Wilderness:” Native American Environmental Management At Yosemite And Contested Conservation Values In America’S National Parks, Rochelle Bloom, Douglas Deur

Anthropology Faculty Publications and Presentations

Chapter 9. The philosophies and views of nature prevalent in the 19th century West shaped the early National Park Service, and continue to influence park policy today. Park-builders incorrectly viewed early parks as untouched “wilderness,” even as Native peoples continued to occupy, revere, and actively manage lands and resources on these lands. This misapprehension fostered the creation and enforcement of park regulations meant to protect wild spaces, resulting in the displacement of both Native peoples and the culturally significant habitats that they had helped sustain for millennia. Among these regulations, federally imposed restrictions on burning and other traditional plant community …

Immunohistochemical Characterization Of A Novel Population Of Reticular Thalamic Neurons Expressing Cholecystokinin And Type 1 Cannabinoid Receptors, Shayna Mallat

Master's Theses and Capstones

The thalamic reticular nucleus (TRN) filters somatosensory stimuli by providing inhibition to the excitatory thalamic relay nuclei, which then communicate with the cortex to appropriately integrate and respond to sensory stimuli. The TRN is also responsible for generating and maintaining sleep spindles, which are important for memory and cognition, and are disrupted in various psychiatric disorders. Previous studies have shown that the TRN is comprised of several neuronal subpopulations that carry out specific functions. These neurons can be distinguished using peptide markers such as parvalbumin (PV), somatostatin (SST), and calbindin (CB). In this thesis, I identified a novel neuronal population …

In A Nutshell: Nutritional And Environmental Factors Impacting Small Mammal Seed Selection In Northeastern Forests, Nicholas Bryan Moore

Master's Theses and Capstones

Rodents often play vital roles in their ecosystems as seed predators and dispersers and can significantly influence the succession and assembly of plant communities. We conducted seed tray experiments to assess the nutritional and environmental factors that influence selection and foraging time of three common rodent granivores: the white-footed mouse (Peromyscus leucopus), the deer mouse (Peromyscus maniculatus), and the southern red-backed vole (Myodes gapperi) for three common seeds: American beech (Fagus grandifolia), red maple (Acer rubrum), and eastern hemlock (Tsuga canadensis). This work was conducted at Bartlett Experimental Forest located within White Mountain National Forest in New Hampshire. Using mixed-effects …

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Pastoral Liturgy

No abstract provided.

Fostering Place-Based Education And Inclusion In The Classroom Through School Grades, Karina Gonzales-Smith

Student Projects for Graduate Degrees

Place-based education expands the space where students learn by connecting to the outdoors, such as garden-based lessons that are dynamic and have a multidisciplinary curriculum. Students are given the opportunity to learn healthy behaviors, environmentally sustainable practices, and life skills. Inclusion is fostered by giving teachers and students agency in the learning experience. The purpose of this study was to view garden education through the lens of place-based education, critical pedagogy, and social justice. To this end, a lesson plan template was created to facilitate future development of garden-based lessons characterized by responsive curriculum and alignment with academic standards. A …

“Mortality’S Wilting Flower:” Terror Management Theory And Music In Animated Films, Lauren Bertsch

Senior Honors Projects

There’s something about animated films - so full of light and wonder - that invokes this “warm and fuzzy” feeling when you sit down to watch it. Yet an entire spectrum of human emotion is demanded from us as an audience. Buried in the heart of animated films are these dark themes, problems that lie in the bedrock of humanity. And it leaves us pondering: why? The answer may actually stretch back to when our species developed thought and reason. In 1973, American anthropologist Ernest Becker uncovered the mental foundation that allows us to live, function, and thrive in a …

Forced Business Closures: Executive Orders By The Governor Closing Private Businesses, Baylee A. Culverhouse, Alexa R. Martin

Georgia State University Law Review

Governor Brian Kemp (R) issued Executive Orders in response to the COVID-19 pandemic that required businesses to close in an effort to limit the spread of the virus. Business owners often challenged those forced business closures as unconstitutional or as exceeding the State’s police power, and those challenges were met with varying degrees of success.

Vol. 97, No. 2: Full Issue, Denver Law Review

Denver Law Review

No abstract provided.

Ctrp3 And Serum Triglycerides In Children Aged 7-10 Years, Arsham Alamian, Jo Ann Marrs, W. Andrew Clark, Kristy L. Thomas, Jonathan M. Peterson

ETSU Faculty Works

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Introduction The prevalence of obesity-related disorders has been steadily increasing over the past couple of decades. Diseases that were once only detected in adults are now prevalent in children, such as hyperlipidemia. The adipose tissue-derived hormonal factor C1q TNF Related Protein 3 (CTRP3) has been linked to triglyceride regulation especially in animal models. However, the relationship between circulating CTRP3 levels and obesity-related disorders in human subjects …

A Narrative Review On The Basic And Clinical Aspects Of The Novel Sars-Cov-2, The Etiologic Agent Of Covid-19., Joseph Hokello, Adhikarimayum Lakhikumar Sharma, Girish C. Shukla, Mudit Tyagi

Center for Translational Medicine Faculty Papers

The novel SARS-CoV-2 is responsible for causing the ongoing outbreak of coronavirus disease 19 (COVID-19), a systemic infection in humans. Ever since it was first detected in December 2019, the number of confirmed cases has continued to increase. Within a short period, this disease has become a global issue, and therefore it is characterized as a pandemic. The current understanding and explanations are based on epidemiological, clinical and physiological observations. Besides, it remains a great challenge, as much remains to be understood about this new disease-causing virus. Therefore, we seek to provide an overview of SARS-CoV-2, including its classification, origin, …

Aging, But Not Sex And Genetic Diversity, Impacts The Pathobiology Of Bacterial Endophthalmitis, Pawan Kumar Singh, Sukhvinder Singh, Robert Emery Wright, Ramandeep Rattan, Ashok Kumar

Obstetrics, Gynecology and Women's Health Services Articles

Purpose: Age, sex, and genetics are important biological variables in determining an individual's susceptibility or response to infectious agents; however, their role has not been evaluated in intraocular infections. In this study, we comprehensively examined the impact of these host biological factors in the pathogenesis of experimental bacterial endophthalmitis.

Methods: Endophthalmitis was induced by intravitreal injection of bacteria (Staphylococcus aureus) in the eyes of male and female C57BL/6 mice of different ages: group I (young, 6-8 weeks), group II (mid-age, 18-20 weeks), and group III (old, 1 year). Highly heterogeneous outbred J:DO mice were used for genetic diversity analysis. Eyes …

Gods Among Men, Christian Burgos

Legacy Theses & Dissertations (2009 - 2024)

Abstract Gods Among Men is a creative text that functions critically to dissect the genre of superhero fiction and bring forth critiques of our culture of worshipping celebrities and political figures. I cite Woody Evans’ work in my critical introduction as being central to my project. Evans puts forth the idea that superheroes are inherently conservative because they are reactive agents that do not proactively change anything. They instead maintain the status quo. Villains, on the other hand, try to effect change for a different end, one they deem better for society. Through the use of characters, this text demonstrates …