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2019

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Optimal Allocation Of Distributed Energy Storage Systems To Improve Performance And Power Quality Of Distribution Networks, Choton K. Das, Octavian Bass, Thair S. Mahmoud, Ganesh Kothapalli, Navid Mousavi, Daryoush Habibi, Mohammad A.S. Masoum Jan 2019

Optimal Allocation Of Distributed Energy Storage Systems To Improve Performance And Power Quality Of Distribution Networks, Choton K. Das, Octavian Bass, Thair S. Mahmoud, Ganesh Kothapalli, Navid Mousavi, Daryoush Habibi, Mohammad A.S. Masoum

Research outputs 2014 to 2021

The placement of grid-scale energy storage systems (ESSs) can have a significant impact on the level of performance improvements of distribution networks. This paper proposes a strategy for optimal allocation of distributed ESSs in distribution networks to simultaneously minimize voltage deviation, flickers, power losses, and line loading. The optimal ESS allocation is investigated through the PQ injection (considering a variable power factor on the dispatch of ESSs) and the results are compared in terms of performance and power quality improvements. An IEEE-33 bus distribution system (medium voltage), having a high influence of renewable (wind and solar) distributed generation, is used …


Is The Blood An Alternative For Programmed Cell Death Ligand 1 Assessment In Non-Small Cell Lung Cancer?, Emmanuel Acheampong, Isaac Spencer, Weitao Lin, Melanie Ziman, Michael Millward, Elin Gray Jan 2019

Is The Blood An Alternative For Programmed Cell Death Ligand 1 Assessment In Non-Small Cell Lung Cancer?, Emmanuel Acheampong, Isaac Spencer, Weitao Lin, Melanie Ziman, Michael Millward, Elin Gray

Research outputs 2014 to 2021

Anti-programmed cell death (PD)-1/PD-ligand 1 (L1) therapies have significantly improved the outcomes for non-small cell lung cancer (NSCLC) patients in recent years. These therapies work by reactivating the immune system and enabling it to target cancer cells once more. There is a general agreement that expression of PD-L1 on tumour cells predicts the therapeutic response to PD-1/PD-L1 inhibitors in NSCLC. Hence, immunohistochemical staining of tumour tissue biopsies from NSCLC patients with PD-L1 antibodies is the current standard used to aid selection of patients for treatment with anti-PD-1 as first line therapy. However, issues of small tissue samples, tissue heterogeneity, the …


Genomic Delineation Of Zoonotic Origins Of Clostridium Difficile, Daniel R. Knight, Thomas V. Riley Jan 2019

Genomic Delineation Of Zoonotic Origins Of Clostridium Difficile, Daniel R. Knight, Thomas V. Riley

Research outputs 2014 to 2021

Clostridium difficile is toxin-producing antimicrobial resistant (AMR) enteropathogen historically associated with diarrhea and pseudomembranous colitis in hospitalized patients. In recent years, there have been dramatic increases in the incidence and severity of C. difficile infection (CDI), and associated morbidity and mortality, in both healthcare and community settings. C. difficile is an ancient and diverse species that displays a sympatric lifestyle, establishing itself in a range of ecological niches external to the healthcare system. These sources/reservoirs include food, water, soil, and over a dozen animal species, in particular, livestock such as pigs and cattle. In a manner analogous to human infection, …


Barriers To Grassroots Innovation: The Phenomenon Of Social-Commercial-Cultural Trilemmas In Remote Indigenous Art Centres, Janice Jones, Pi-Shen Seet, Tim Acker, Michelle Whittle Jan 2019

Barriers To Grassroots Innovation: The Phenomenon Of Social-Commercial-Cultural Trilemmas In Remote Indigenous Art Centres, Janice Jones, Pi-Shen Seet, Tim Acker, Michelle Whittle

Research outputs 2014 to 2021

Despite substantial research on grassroots innovation, there is a lack of understanding on the barriers to grassroots innovation. We examine paradoxes that arise as a consequence of multiple, often conflicting, objectives in remote art centres, social enterprises that are key sites for grassroots innovations. We investigate how social, commercial and cultural logics in remote Indigenous art centres contribute to an on-going trilemma that acts as a barrier to the development of grassroots innovation. We also explore the challenges and opportunities managers encounter in reconciling these multiple, often conflicting, logics. The results indicate that although art centres have dual social and …


A Note On Science, Legal Research And Artificial Intelligence, Sean Goltz, Giulia Dondoli Jan 2019

A Note On Science, Legal Research And Artificial Intelligence, Sean Goltz, Giulia Dondoli

Research outputs 2014 to 2021

This paper discusses the principles of scientific research and in turn review legal research that was done using Artificial Intelligence arguing that it is the tools (Artificial Intelligence) that take center stage while the meaning (legal research) is left back stage. In turn, this kind of research does not adhere to the fundamentals of scientific research nor comply with scientific and industry ethical codes.


Offline Versus Online Travel Experience Sharing: The National Profile Of China, Songshan (Sam) Huang, Xiang Wei Jan 2019

Offline Versus Online Travel Experience Sharing: The National Profile Of China, Songshan (Sam) Huang, Xiang Wei

Research outputs 2014 to 2021

Purpose: This study aims to examine the demographic differences of Chinese nationals’ travel experience sharing through different offline and online platforms.

Design/methodology/approach: Cross-tabulation analysis was applied on a national sample of 6081 respondents in China.

Findings: The study found that Chinese women tend to share travel experience more often than Chinese men; old people in China tend to use the face-to-face approach more than online or social media to share their travel experience. About 66.5 per cent of the survey sample used WeChat Moments to share their travel experience, highlighting WeChat as the dominating social media platform in China for …


Fractional Anisotropy Of Thalamic Nuclei Is Associated With Verticality Misperception After Extra-Thalamic Stroke, Taiza E. G. Santos, Jussara A. O. Baggio, Carlo Rondinoni, Laura Machado, Karina T. Weber, Luiz H. Stefano, Antonio C. Santos, Octavio M. Pontes-Neto, Joao P. Leite, Dylan J. Edwards Jan 2019

Fractional Anisotropy Of Thalamic Nuclei Is Associated With Verticality Misperception After Extra-Thalamic Stroke, Taiza E. G. Santos, Jussara A. O. Baggio, Carlo Rondinoni, Laura Machado, Karina T. Weber, Luiz H. Stefano, Antonio C. Santos, Octavio M. Pontes-Neto, Joao P. Leite, Dylan J. Edwards

Research outputs 2014 to 2021

Verticality misperception after stroke is a frequent neurological deficit that leads to postural imbalance and a higher risk of falls. The posterior thalamic nuclei are described to be involved with verticality perception, but it is unknown if extra-thalamic lesions can have the same effect via diaschisis and degeneration of thalamic nuclei. We investigated the relationship between thalamic fractional anisotropy (FA, a proxy of structural integrity), and verticality perception, in patients after stroke with diverse encephalic extra-thalamic lesions. We included 11 first time post-stroke patients with extra-thalamic primary lesions, and compared their region-based FA to a group of 25 age-matched healthy …


A Systematic Review Of The Antecedents And Prevalence Of Suicide, Self-Harm And Suicide Ideation In Australian Aboriginal And Torres Strait Islander Youth, Joanne M. Dickson, Kate Cruise, Clare A. Mccall, Peter J. Taylor Jan 2019

A Systematic Review Of The Antecedents And Prevalence Of Suicide, Self-Harm And Suicide Ideation In Australian Aboriginal And Torres Strait Islander Youth, Joanne M. Dickson, Kate Cruise, Clare A. Mccall, Peter J. Taylor

Research outputs 2014 to 2021

Suicide and self-harm represent serious global health problems and appear to be especially elevated amongst indigenous minority groups, and particularly amongst young people (aged 24 years or younger). This systematic review investigates for the first time the antecedents and prevalence of suicide, self-harm and suicide ideation among Australian Aboriginal and Torres Strait Islander youth. Web of Science, PubMed, PsychINFO, CINAHL databases and grey literature were searched from earliest records to April 2019 for eligible articles. Twenty-two empirical articles met the inclusion criteria. The data confirmed that indigenous youth in Australia have elevated rates of suicide, self-harm and suicidal ideation relative …


Cetacean Sightings Within The Great Pacific Garbage Patch, Susan E. Gibbs, Chandra P. Salgado Kent, Boyan Slat, Damien Morales, Leila Fouda, Julia Reisser Jan 2019

Cetacean Sightings Within The Great Pacific Garbage Patch, Susan E. Gibbs, Chandra P. Salgado Kent, Boyan Slat, Damien Morales, Leila Fouda, Julia Reisser

Research outputs 2014 to 2021

Here, we report cetacean sightings made within a major oceanic accumulation zone for plastics, often referred to as the ‘Great Pacific Garbage Patch’ (GPGP). These cetacean records occurred in October 2016 and were made by sensors and trained observers aboard a Hercules C-130 aircraft surveying the GPGP at 400 m height and 140 knots speed. Four sperm whales (including a mother and calf pair), three beaked whales, two baleen whales, and at least five other cetaceans were observed. Many surface drifting plastics were also detected, including fishing nets, ropes, floats and fragmented debris. Some of these objects were close to …


Rates Of Age- And Amyloid Β-Associated Cortical Atrophy In Older Adults With Superior Memory Performance, Christa Dang, Nawaf Yassi, Karra D. Harrington, Ying Xia, Yen Ying Lim, David Ames, Simon M. Laws, Martha Hickey, Stephanie Rainey-Smith, Hamid R. Sohrabi, James D. Doecke, Jurgen Fripp, Olivier Salvado, Peter J. Snyder, Michael Weinborn, Victor L. Villemagne, Christopher C. Rowe, Colin L. Masters, Paul Maruff Jan 2019

Rates Of Age- And Amyloid Β-Associated Cortical Atrophy In Older Adults With Superior Memory Performance, Christa Dang, Nawaf Yassi, Karra D. Harrington, Ying Xia, Yen Ying Lim, David Ames, Simon M. Laws, Martha Hickey, Stephanie Rainey-Smith, Hamid R. Sohrabi, James D. Doecke, Jurgen Fripp, Olivier Salvado, Peter J. Snyder, Michael Weinborn, Victor L. Villemagne, Christopher C. Rowe, Colin L. Masters, Paul Maruff

Research outputs 2014 to 2021

Introduction: Superior cognitive performance in older adults may reflect underlying resistance to age-associated neurodegeneration. While elevated amyloid b (Ab) deposition (Ab1) has been associated with increased cortical atrophy, it remains unknown whether “SuperAgers” may be protected from Ab-associated neurodegeneration. Methods: Neuropsychologically defined SuperAgers (n 5 172) and cognitively normal for age (n 5 172) older adults from the Australian Imaging, Biomarkers and Lifestyle study were case matched. Rates of cortical atrophy over 8 years were examined by SuperAger classification and Ab status. Results: Of the case-matched SuperAgers and cognitively normal for age older adults, 40.7% and 40.1%, respectively, were Ab1. …


Distilling And Applying Criteria For Best Practice Eia Follow-Up, Elise Pinto, Angus Morrison-Saunders, Alan Bond, Jenny Pope, Francois Retief Jan 2019

Distilling And Applying Criteria For Best Practice Eia Follow-Up, Elise Pinto, Angus Morrison-Saunders, Alan Bond, Jenny Pope, Francois Retief

Research outputs 2014 to 2021

Follow-up is an essential component of Environmental Impact Assessment (EIA) if the success of EIA in improving the sustainability of a project once implemented is to be determined. This paper aims to establish universally-applicable criteria for EIA follow-up to evaluate project performance once assessed and underway. A suite of 24 criteria is derived from EIA follow-up best practice principles published by the International Association for Impact Assessment. The criteria are categorized according to the five dimensions of EIA follow-up: monitoring, evaluation, management, communication and governance. Posed as questions, the criteria support qualitative assessments of EIA follow-up performance for a project. …


Acute Effects Of Fine Particulate Matter (Pm2.5) On Hospital Admissions For Cardiovascular Disease In Beijing, China: A Time-Series Study, Endawoke Amsalu, Tianqi Wang, Haibin Li, Yue Liu, Anxin Wang, Xiangtong Liu, Lixin Tao, Yanxia Luo, Feng Zhang, Xinghua Yang, Xia Li, Wei Wang, Xiuhua Guo Jan 2019

Acute Effects Of Fine Particulate Matter (Pm2.5) On Hospital Admissions For Cardiovascular Disease In Beijing, China: A Time-Series Study, Endawoke Amsalu, Tianqi Wang, Haibin Li, Yue Liu, Anxin Wang, Xiangtong Liu, Lixin Tao, Yanxia Luo, Feng Zhang, Xinghua Yang, Xia Li, Wei Wang, Xiuhua Guo

Research outputs 2014 to 2021

Background

Air pollution and cardiovascular disease are increasing problems in China. However, the short-term association between fine particulate matter (PM2.5) and cardiovascular disease (CVD) is not well documented. The purpose of this study is to estimate the short-term effects of PM2.5 on CVD admissions in Beijing, China.

Methods

In total, 460,938 electronic hospitalization summary reports for CVD between 2013 and 2017 were obtained. A generalized additive model using a quasi-Poisson distribution was used to investigate the association between exposure to PM2.5 and hospitalizations for total and cause-specific CVD, including coronary heart disease (CHD), atrial fibrillation (AF), and heart failure (HF) …


Patient-Defined Meaningfulness Within Chronic Pain Rehabilitation: A Concept Analysis, Katrina Liddiard, Annette J. Raynor, Annette M. Rivard, Cary A. Brown Jan 2019

Patient-Defined Meaningfulness Within Chronic Pain Rehabilitation: A Concept Analysis, Katrina Liddiard, Annette J. Raynor, Annette M. Rivard, Cary A. Brown

Research outputs 2014 to 2021

Background: As the problem of chronic pain grows worldwide, rehabilitation is critical to improved patient well-being. There is thus a need for rehabilitation-focused research. It appears that outcomes are improved when patients perceive the rehabilitation process to be meaningful. However, there is no empirical evidence determining how this would be achieved. An important first step is to identify and describe the concept of meaningfulness as it is used in the chronic pain rehabilitation literature. Objective: This paper reports the findings of a structured concept analysis to define meaningfulness from the patient perspective in chronic pain rehabilitation. Methodology: In consultation with …


Assessing The Variability And Predictability Of Adipokines (Adiponectin, Leptin, Resistin And Their Ratios) In Non-Obese And Obese Women With Anovulatory Polycystic Ovary Syndrome, Christian Obirikorang, William K. B. A. Owiredu, Sandra Adu-Afram, Emmanuel Acheampong, Evans Adu Asamoah, Enoch Kwabena Antwi-Boasiakoh, Eddie-Williams Owiredu Jan 2019

Assessing The Variability And Predictability Of Adipokines (Adiponectin, Leptin, Resistin And Their Ratios) In Non-Obese And Obese Women With Anovulatory Polycystic Ovary Syndrome, Christian Obirikorang, William K. B. A. Owiredu, Sandra Adu-Afram, Emmanuel Acheampong, Evans Adu Asamoah, Enoch Kwabena Antwi-Boasiakoh, Eddie-Williams Owiredu

Research outputs 2014 to 2021

Objectives

To assess the variability and predictability of adiponectin, leptin, resistin and their ratios in non-obese and obese women with anovulatory polycystic ovary syndrome (aPCOS).

Results

A total of 52 ovulatory controls (mean age = 31.63 ± 4.88 years, BMI = 25.33 ± 2.68 kg/m2); 54 non-obese (mean age = 32.11 ± 4.25 years, BMI = 25.72 ± 2.95 kg/m2) and 50 obese women with aPCOS (mean age = 33.64 ± 4.14 years, BMI = 39.19 ± 2.99 kg/m2) were recruited. The aPCOS group had lower adiponectin [13.0 (10.49–16.59) vs 18.42 (15.72–19.92) µg/ml, p < 0.0001], adiponectin: leptin ratio (A:L) [0.60 (0.35–0.88) vs 1.19 (0.92–1.37), p < 0.0001], and adiponectin: resistin ratio (A:R) [0.30 (0.21–0.43) vs 0.42 (0.32–0.62), p < 0.0001] but a higher leptin [20.02 (14.54–26.80) vs 16.17 (14.51–18.36) ng/ml, p < 0.0001] and leptin: resistin ratio (L:R) [0.53 (0.37–0.82) vs 0.40 (0.27–0.48), p < 0.0001] compared to the controls. The obese aPCOS group had lower adiponectin [11.04 (5.66–13.25) vs 14.18 (11.04–18.02), p < 0.0001 and 18.42 (15.72–19.92) µg/ml, p < 0.0001], A:L [0.36 (0.27–0.44) vs 0.78 (0.61–1.16), p < 0.0001 and 1.19 (0.92–1.37), p < 0.0001], and A:R [0.24 (0.17–0.38) vs 0.40 (0.23–0.58), p < 0.0001 and 0.42 (0.32–0.62), p < 0.0001] but a higher leptin [26.80 (14.28–32.09) vs 17.95 (14.86–21.26), p < 0.05 and 16.17 (14.51–18.36) ng/ml, p < 0.0001] and L:R [0.63 (0.46–1.03) vs 0.41 (0.30–0.61), p < 0.0001 and 0.40 (0.27–0.48), p < 0.0001] compared to the non-obese aPCOS and control group, respectively. A:L showed the best discriminatory power in predicting aPCOS (AUC = 0.83), followed by adiponectin alone (AUC = 0.79), L:R and leptin alone (both AUC = 0.69). Resistin alone had the poorest discriminatory power (AUC = 0.48).


Paired Associative Stimulation As A Tool To Assess Plasticity Enhancers In Chronic Stroke, Joshua Silverstein, Mar Cortes, Katherine Z. Tsagaris, Alejandra Climent, Linda M. Gerber, Clara Oromendia, Pasquale Fonzetti, Rajiv R. Ratan, Tomoko Kitago, Marco Iacoboni, Allan Wu, Bruce Dobkin, Dylan J. Edwards Jan 2019

Paired Associative Stimulation As A Tool To Assess Plasticity Enhancers In Chronic Stroke, Joshua Silverstein, Mar Cortes, Katherine Z. Tsagaris, Alejandra Climent, Linda M. Gerber, Clara Oromendia, Pasquale Fonzetti, Rajiv R. Ratan, Tomoko Kitago, Marco Iacoboni, Allan Wu, Bruce Dobkin, Dylan J. Edwards

Research outputs 2014 to 2021

Background and Purpose: The potential for adaptive plasticity in the post-stroke brain is difficult to estimate, as is the demonstration of central nervous system (CNS) target engagement of drugs that show promise in facilitating stroke recovery. We set out to determine if paired associative stimulation (PAS) can be used (a) as an assay of CNS plasticity in patients with chronic stroke, and (b) to demonstrate CNS engagement by memantine, a drug which has potential plasticity-modulating effects for use in motor recovery following stroke.

Methods: We examined the effect of PAS in fourteen participants with chronic hemiparetic stroke at five time-points …


Calculation Of Oxygen Diffusion Coefficients In Oxide Films Formed On Low-Temperature Annealed Zr Alloys And Their Related Corrosion Behavior, Lina Zhang, Liang-Yu Chen, Cuihua Zhao, Yujing Liu, Lai-Chang Zhang Jan 2019

Calculation Of Oxygen Diffusion Coefficients In Oxide Films Formed On Low-Temperature Annealed Zr Alloys And Their Related Corrosion Behavior, Lina Zhang, Liang-Yu Chen, Cuihua Zhao, Yujing Liu, Lai-Chang Zhang

Research outputs 2014 to 2021

The growth of oxide film, which results from the inward oxygen diffusion from a corrosive environment, is a critical consideration for the corrosion resistance of zirconium alloys. This work calculates the oxygen diffusion coefficients in the oxide films formed on zirconium alloys annealed at 400~500 °C and investigates the related corrosion behavior. The annealed samples have a close size for the second-phase particles but a distinctive hardness, indicating the difference in substrate conditions. The weight gain of all samples highly follows parabolic laws. The weight gain of the sample annealed at 400 °C has the fastest increase rate at the …


Interplay Between Residual Protease Activity In Commercial Lactases And The Subsequent Digestibility Of Β-Casein In A Model System, Di Zhao, Thao T. Le, Lotte B. Larsen, Yingqun Nian, Cong Wang, Chunbao Li, Guanghong Zhou Jan 2019

Interplay Between Residual Protease Activity In Commercial Lactases And The Subsequent Digestibility Of Β-Casein In A Model System, Di Zhao, Thao T. Le, Lotte B. Larsen, Yingqun Nian, Cong Wang, Chunbao Li, Guanghong Zhou

Research outputs 2014 to 2021

One of the conventional ways to produce lactose-hydrolyzed (LH) milk is via the addition of commercial lactases into heat-treated milk in which lactose is hydrolyzed throughout storage. This post-hydrolysis method can induce proteolysis in milk proteins due to protease impurities remaining in commercial lactase preparations. In this work, the interplay between lactose hydrolysis, proteolysis, and glycation was studied in a model system of purified β-casein (β-CN), lactose, and lactases using peptidomic methods. With a lactase presence, the proteolysis of β-CN was found to be increased during storage. The protease side-activities mainly acted on the hydrophobic C-terminus of β-CN at Ala, …


Unlocking The Decibel Scoreplayer, Aaron Wyatt, Lindsay Vickery, Stuart James Jan 2019

Unlocking The Decibel Scoreplayer, Aaron Wyatt, Lindsay Vickery, Stuart James

Research outputs 2014 to 2021

This paper discusses recent developments in the Decibel ScorePlayer project, including the introduction of a canvas scoring mode, python ScorePlayer externals, and enhancements to the ScoreCreator application. Firstly, the canvas scoring mode of the Decibel ScorePlayer app allows for other applications, such as Max, to send drawing commands to the ScorePlayer via OSC. Several examples of implementations of generative and animated notation scores are discussed and evaluated. An object model has been developed allowing for the creation of hierarchies of drawn elements. The object model defines a framework of commands that can be used to create and control these objects, …


Perceptions Of Climate Change And Occupational Heat Stress Risks And Adaptation Strategies Of Mining Workers In Ghana, Victor Fannam Nunfam, Jacques Oosthuizen, Kwadwo Adusei-Asante, Eddie Van Etten, Kwasi Frimpong Jan 2019

Perceptions Of Climate Change And Occupational Heat Stress Risks And Adaptation Strategies Of Mining Workers In Ghana, Victor Fannam Nunfam, Jacques Oosthuizen, Kwadwo Adusei-Asante, Eddie Van Etten, Kwasi Frimpong

Research outputs 2014 to 2021

Heavy physical workload for long hours coupled with increasing workplace heat exposure due to rising temperatures stemming from climate change, especially where there are inadequate prevention and control policies, adversely affect workers' health and safety, productive capacity and social well-being. However, variations in workers' concerns and awareness of occupational heat stress and climate change risks impede the effectiveness of heat stress management. A mixed method approach was used to assess climate change perceptions and occupational heat stress risks and adaptation strategies of Ghanaian mining workers. Questionnaires and focus group discussions were used to collect data from 320 respondents. Quantitative and …


Sandwich-Structured, Damage-Resistant Tin/Graded Tisin/Tisin Film, Shuang Peng, Jiang Xu, Paul Munroe, Zonghan Xie Jan 2019

Sandwich-Structured, Damage-Resistant Tin/Graded Tisin/Tisin Film, Shuang Peng, Jiang Xu, Paul Munroe, Zonghan Xie

Research outputs 2014 to 2021

The development of hard, multi-layer coatings is an effective strategy to enhance the wear resistance of cutting tools and so extend their service life. In the present study, a sandwich structured TiN/g-TiSiN/TiSiN film (where a graded (g-) TiSiN layer with an increasing Si content from 0 to 10 at% was inserted as a transitional layer between the TiN layer and the TiSiN layer with a fixed silicon content of 10 at%) was prepared on to a M42 tool steel substrate. Its mechanical properties were compared to both a dual-layered TiN/g-TiSiN film and a monolithic TiN film. Nanoindentation testing, assisted by …


Degradation And Hydrate Phase Equilibria Measurement Methods Of Monoethylene Glycol, Khalid Alef, Stefan Iglauer, Ahmed Barifcani Jan 2019

Degradation And Hydrate Phase Equilibria Measurement Methods Of Monoethylene Glycol, Khalid Alef, Stefan Iglauer, Ahmed Barifcani

Research outputs 2014 to 2021

Monoethylene glycol (MEG), a common chemical used for the inhibition of gas hydrate formation may undergo degradation in the regeneration/reclamation process. Limited research exists on the effect of degradation of MEG on hydrate formation, production facilities and equipment especially in the presence of other chemical additives. The proposed method allows for streamlining the process of preparing, degrading and analysis of MEG solutions for hydrate testing and degradation products.

•

Procedure to prepare accurate MEG solutions avoiding oxidative degradation of MEG (i.e., controlling oxygen ingress).

•

Two methods are suggested to mimic field-like degradation of MEG solutions (i.e., degradation by reclamation …


Time-To-Event Analysis For Sports Injury Research Part 1: Time-Varying Exposures, Rasmus Oestergaard Nielsen, Michael Lejbach Bertelsen, Daniel Ramskov, Merete Møller, Adam Hulme, Daniel Theisen, Caroline F. Finch, Lauren Victoria Fortington, Mohammad Ali Mansournia, Erik Thorlund Parner Jan 2019

Time-To-Event Analysis For Sports Injury Research Part 1: Time-Varying Exposures, Rasmus Oestergaard Nielsen, Michael Lejbach Bertelsen, Daniel Ramskov, Merete Møller, Adam Hulme, Daniel Theisen, Caroline F. Finch, Lauren Victoria Fortington, Mohammad Ali Mansournia, Erik Thorlund Parner

Research outputs 2014 to 2021

BACKGROUND: ‘How much change in training load is too much before injury is sustained, among different athletes?’ is a key question in sports medicine and sports science. To address this question the investigator/practitioner must analyse exposure variables that change over time, such as change in training load. Very few studies have included time-varying exposures (eg, training load) and time-varying effect-measure modifiers (eg, previous injury, biomechanics, sleep/stress) when studying sports injury aetiology.

AIM: To discuss advanced statistical methods suitable for the complex analysis of time-varying exposures such as changes in training load and injury-related outcomes.

CONTENT: Time-varying exposures and time-varying effect-measure …


Time-To-Event Analysis For Sports Injury Research Part 2: Time-Varying Outcomes, Rasmus Oestergaard Nielsen, Michael Lejbach Bertelsen, Daniel Ramskov, Merete Møller, Adam Hulme, Daniel Theisen, Caroline F. Finch, Lauren Victoria Fortington, Mohammad Ali Mansournia, Erik Thorlund Parner Jan 2019

Time-To-Event Analysis For Sports Injury Research Part 2: Time-Varying Outcomes, Rasmus Oestergaard Nielsen, Michael Lejbach Bertelsen, Daniel Ramskov, Merete Møller, Adam Hulme, Daniel Theisen, Caroline F. Finch, Lauren Victoria Fortington, Mohammad Ali Mansournia, Erik Thorlund Parner

Research outputs 2014 to 2021

BACKGROUND: Time-to-event modelling is underutilised in sports injury research. Still, sports injury researchers have been encouraged to consider time-to-event analyses as a powerful alternative to other statistical methods. Therefore, it is important to shed light on statistical approaches suitable for analysing training load related key-questions within the sports injury domain.

CONTENT: In the present article, we illuminate: (i) the possibilities of including time-varying outcomes in time-to-event analyses, (ii) how to deal with a situation where different types of sports injuries are included in the analyses (ie, competing risks), and (iii) how to deal with the situation where multiple subsequent injuries …


Anti-Inflammatory, Anti-Nociceptive And Antipyretic Activity Of Young And Old Leaves Of Vernonia Amygdalina, Du-Bois Asante, Isaac Tabiri Henneh, Desmond Omane Acheampong, Foster Kyei, Christian Kweku Adokoh, Eric Gyamerah Ofori, Nelson Kwabla Domey, Emmanuel Adakudugu, Lokeswari Prathyusha Tangella, Elvis Ofori Ameyaw Jan 2019

Anti-Inflammatory, Anti-Nociceptive And Antipyretic Activity Of Young And Old Leaves Of Vernonia Amygdalina, Du-Bois Asante, Isaac Tabiri Henneh, Desmond Omane Acheampong, Foster Kyei, Christian Kweku Adokoh, Eric Gyamerah Ofori, Nelson Kwabla Domey, Emmanuel Adakudugu, Lokeswari Prathyusha Tangella, Elvis Ofori Ameyaw

Research outputs 2014 to 2021

Background

Both young and old leaves of Vernonia amygdalina (VA) are traditionally used to treat inflammation, pain and fever. However, the efficacy of young and old leaves for treating these ailments have not been compared till date.

Aim

To ascertain the effect of young and old leaves of VA in managing inflammation, pain and fever.

Methods

Both quantitative and qualitative phytochemical screening of ethanol extracts of young (EthYL) and old (EthOL) leaves of VA were performed. The anti-inflammatory activity of orally administered EthYL and EthOL (50–200 mg/kg) and Diclofenac (10 mg/kg) were evaluated in carrageenan-induced inflammation model in rats. Antipyretic …


Effect Of Direct Current Electric Field Intensity And Electrolyte Layer Thickness On Oxygen Reduction In Simulated Atmospheric Environment, Xin Zhang, Junxi Zhang, Qimeng Chen, Nianwei Dai, Qingzhao Ni, Lai-Chang Zhang, Fahe Cao, Jianqing Zhang Jan 2019

Effect Of Direct Current Electric Field Intensity And Electrolyte Layer Thickness On Oxygen Reduction In Simulated Atmospheric Environment, Xin Zhang, Junxi Zhang, Qimeng Chen, Nianwei Dai, Qingzhao Ni, Lai-Chang Zhang, Fahe Cao, Jianqing Zhang

Research outputs 2014 to 2021

The effect of direct current (DC) electric field and electrolyte layer thickness on oxygen reduction in simulated atmospheric environment were investigated using electrochemical measurements. The results show that the limiting diffusion current density (ilim) decreases with increasing the thin electrolyte layers (TELs) thickness but it increases with increasing the DC electric field intensity. The potential shifts negatively with the DC electric field. It is found that the DC electric field enables OH− ions to quickly migrate from the solution/electrode interface to the electrolyte layer. All these features promote the cathodic reduction process thereby enhancing the metal …


Investigating The Relationships Between Hypothalamic Volume And Measures Of Circadian Rhythm And Habitual Sleep In Premanifest Huntington's Disease, Danielle M. Bartlett, Juan F. Domínguez D, Alvaro Reyes, Pauline Zaenker, Kirk W. Feindel, Robert U. Newton, Anthony J. Hannan, James A. Slater, Peter R. Eastwood, Alpar S. Lazar, Mel Ziman, Travis Cruickshank Jan 2019

Investigating The Relationships Between Hypothalamic Volume And Measures Of Circadian Rhythm And Habitual Sleep In Premanifest Huntington's Disease, Danielle M. Bartlett, Juan F. Domínguez D, Alvaro Reyes, Pauline Zaenker, Kirk W. Feindel, Robert U. Newton, Anthony J. Hannan, James A. Slater, Peter R. Eastwood, Alpar S. Lazar, Mel Ziman, Travis Cruickshank

Research outputs 2014 to 2021

Objective

Pathological changes within the hypothalamus have been proposed to mediate circadian rhythm and habitual sleep disturbances in individuals with Huntington’s disease (HD). However, investigations examining the relationships between hypothalamic volume and circadian rhythm and habitual sleep in individuals with HD are sparse. This study aimed to comprehensively evaluate the relationships between hypothalamic pathology and circadian rhythm and habitual sleep disturbances in individuals with premanifest HD.

Methods

Thirty-two individuals with premanifest HD and twenty-nine healthy age- and gender-matched controls participated in this dual-site, cross-sectional study. Magnetic resonance imaging scans were performed to evaluate hypothalamic volume. Circadian rhythm and habitual sleep …


Chemically Dealloyed Fe-Based Metallic Glass With Void Channels-Like Architecture For Highly Enhanced Peroxymonosulfate Activation In Catalysis, J.C. Wang, S.X. Liang, Z. Jia, W.C. Zhang, W.M. Wang, Y.J. Lui, J. Lu, L.C Zhang Jan 2019

Chemically Dealloyed Fe-Based Metallic Glass With Void Channels-Like Architecture For Highly Enhanced Peroxymonosulfate Activation In Catalysis, J.C. Wang, S.X. Liang, Z. Jia, W.C. Zhang, W.M. Wang, Y.J. Lui, J. Lu, L.C Zhang

Research outputs 2014 to 2021

Metallic glasses (MGs) with their intrinsic disordered atomic structure and widely controllable atomic components have recently emerged as fascinating functional materials in wastewater treatment. Compared to crystalline alloys, the less-noble atomic components in monolithic metallic glass are more efficient to be selectively dissolved during dealloying process. This work reported a facile chemical dealloying approach to fabricate a void channels-like structured MG with the elemental components of Fe73.5Si13.5B9Cu1Nb3 for methylene blue (MB) degradation. Results indicated that the dealloyed Fe73.5Si13.5B9Cu1Nb3 MGs with the void channels-like morphology presented a significant improvement of catalytic efficiency and reusability. The dye degradation reaction rate (kobs) of …


Diets High In N-3 Fatty Acids Are Associated With Lower Arterial Stiffness In Patients With Rheumatoid Arthritis: A Latent Profile Analysis, Richard J. Woodman, Leena R. Baghdadi, E Michael Shanahan, Inushi De Silva, Jonathan M. Hodgson, Arduino A. Mangoni Jan 2019

Diets High In N-3 Fatty Acids Are Associated With Lower Arterial Stiffness In Patients With Rheumatoid Arthritis: A Latent Profile Analysis, Richard J. Woodman, Leena R. Baghdadi, E Michael Shanahan, Inushi De Silva, Jonathan M. Hodgson, Arduino A. Mangoni

Research outputs 2014 to 2021

Supplementation with n-3 fatty acids can influence inflammation and markers of arterial stiffness that are increased in patients with rheumatoid arthritis (RA). However, it is unknown whether specific patterns of dietary fatty acid intake are similarly associated. In a longitudinal study, eighty-six RA patients reported their dietary intake and had arterial stiffness measured using the augmentation index (AIx) at baseline and 8 months. Latent profile analysis (LPA) was performed to characterise patterns of fatty acid intake using sixteen major fatty acids. Models for two to six profiles were compared using the Akaike and Bayesian information criteria. Associations between AIx and …


Monitoring Melanoma Recurrence With Circulating Tumor Dna: A Proof Of Concept From Three Case Studies, Ashleigh C. Mcevoy, Michelle R. Pereira, Anna Reid, Robert Pearce, Lester Cowell, Zeyad Al-Ogaili, Muhammad A. Khattak, Michael Millward, Tarek M. Meniawy, Elin S. Gray, Melanie R. Ziman Jan 2019

Monitoring Melanoma Recurrence With Circulating Tumor Dna: A Proof Of Concept From Three Case Studies, Ashleigh C. Mcevoy, Michelle R. Pereira, Anna Reid, Robert Pearce, Lester Cowell, Zeyad Al-Ogaili, Muhammad A. Khattak, Michael Millward, Tarek M. Meniawy, Elin S. Gray, Melanie R. Ziman

Research outputs 2014 to 2021

Background: A significant number of melanoma patients experience recurrence to distant sites, despite having had surgical treatment of the primary lesion, with curative intent. Monitoring of patients for early evidence of disease recurrence would significantly improve management of the disease, allowing timely therapeutic intervention. Circulating tumor DNA (ctDNA) is becoming a well-recognized biomarker for monitoring malignancies and has, in a few studies, been shown to signify disease recurrence earlier than conventional methods.

Methods: We performed a retrospective analysis of plasma ctDNA using droplet digital PCR (ddPCR) in 30 primary melanoma patients with tumors harboring BRAF, NRAS or TERT promoter mutations. …


Strategies To Improve The Thermal Performance Of Heat Pipe Solar Collectors In Solar Systems: A Review, Abdellah Sharifian, Mehdi Khiadani, Ataollah Nosrati Jan 2019

Strategies To Improve The Thermal Performance Of Heat Pipe Solar Collectors In Solar Systems: A Review, Abdellah Sharifian, Mehdi Khiadani, Ataollah Nosrati

Research outputs 2014 to 2021

Invention of evacuated tube heat pipe solar collectors (HPSCs) was a huge step forward towards resolving the challenges of conventional solar systems due to their unique features and advantages. This has led to their utilization in a wide range of solar applications surpassing other conventional collectors. However, relatively low thermal efficiency of heat pipe solar (HPS) systems is still the major challenge of solar industry evidenced by numerous studies conducted mainly during the last decade to improve their efficiency. To date, several review papers have been published summarizing studies relevant to utilization of HPSCs in various thermal applications. However, to …