Digital Commons Network^™

Clonally Expanded Alpha-Chain T-Cell Receptor (Tcr) Transcripts Are Present In Aneurysmal Lesions Of Patients With Abdominal Aortic Aneurysm (Aaa), Song Lu, John V. White, Raquel I. Judy, Lisa L. Merritt, Wan Lu Lin, Xiaoying Zhang, Charalambos Solomides, Ifeyinwa Nwaneshiudu, John Gaughan, Dimitri S. Monos, Emilia L. Oleszak, Chris D. Platsoucas

Biological Sciences Faculty Publications

Abdominal aortic aneurysm (AAA) is a life-threatening immunological disease responsible for 1 to 2% of all deaths in 65 year old or older individuals. Although mononuclear cell infiltrates have been demonstrated in AAA lesions and autoimmunity may be responsible for the initiation and account for the propagation of the disease, the information available about the pathogenesis of AAA is limited. To examine whether AAA lesions from patients with AAA contain clonally expanded α-chain TCR transcripts, we amplified by the non-palindromic adaptor-PCR (NPA-PCR)/Vα-specific PCR and/or the Vα-specific PCR these α-chain TCR transcripts. The amplified transcripts were cloned and sequenced. Substantial proportions …

Flexible Liminality Among The Tibetan Diaspora: Tibetan Exiles Adjusting Cultural Practices In Dharamsala, India And The United States, Sneha Thapa

Theses and Dissertations--Anthropology

In this dissertation, I investigate the characteristics and quality of liminality among the Tibetan exile community in Dharamsala, India, and the United States. I argue that the quality of their liminality defines this exile community’s ability to maneuver and voice their influence to geo-political community of states that surround them, all while within their liminal condition. The Tibetan exile people live as stateless foreigners in India but have a better standard of living and better opportunities to acquire transnational resources than their surrounding host community. In the U.S., Tibetan diaspora people live as asylum-seekers and naturalized Tibetan-Americans but have established …

Finding The Singing Spruce: Craft Labor, Global Forests, And Musical Instrument Makers In Appalachia, Jasper Waugh-Quasebarth

Theses and Dissertations--Anthropology

Musical instrument makers in the state of West Virginia in the United States pursue “singing,” lively instruments that capture ideals of musical tone and “re-enchant” their work and lives through relationships with craft materials and the forest landscape. Suitable tonewoods that grow in the region, such as red spruce (Picea rubens), intersect with makers’ desires to craft instruments in the style of famed makers such as the C.F. Martin Company and the Gibson Company as well as provide instruments imbued with a sense of place. While the demand for and symbolic import of instruments made with local wood …

Consuming Appalachia: An Archaeology Of Company Coal Towns, Zada Komara

Theses and Dissertations--Anthropology

Material culture is an understudied aspect of social life in Appalachian Studies, the multi- disciplinary investigation of social life in the Appalachian region. Historically, material culture in the region has been largely studied for its semiotic properties, decoded as a tangible symbol of “a region apart,” lagging behind the rest of America in terms of moral, mental, economic, and social development. Critical material studies from archaeology and other disciplines paint a different picture, however, and construct a region as American as any other. This study utilizes discourse analysis of material rhetoric about Appalachia and archaeological and oral historical data from …

Middle To Late Holocene (7200-2900 Cal. Bp) Archaeological Site Formation Processes At Crumps Sink And The Origins Of Anthropogenic Environments In Central Kentucky, Usa, Justin Nels Carlson

Theses and Dissertations--Anthropology

Though some researchers have argued that the Big Barrens grasslands of Kentucky were the product of anthropogenic land clearing practices by Native Americans, heretofore, this hypothesis had not been tested archaeologically. More work was needed to refine chronologies of fire activity in the region, determine the extent to which humans played a role in the process, and integrate these findings with the paleoenvironmental and archaeological record. With these goals in mind, I conducted archaeological and geoarchaeological investigations at Crumps Sink in the Sinkhole Plain of Kentucky. The archaeological record and site formation history of Crumps Sink were compared with environmental …

The Wages Of Precarious Work: An Ethnography Of Upstate South Carolina’S Reserve Army Of The Laboring, Henry Bundy

Theses and Dissertations--Anthropology

The proliferation of precarious work represents a sea change in the opportunity structure of the new economies of the American South. As the role of the State has shifted from guarantor of rights and services to anxious custodian of economic liberalization, Americans have been enjoined to shoulder ever-larger shares of the responsibilities and risks associated with wage labor. As a result, the working poor have been left to weather the vicissitudes of the unfettered market with the increasingly paltry social membership guaranteed through waged employment. Among the risks now frequently assumed by individuals, are the responsibilities of health.

In the …

Making Experts: An Ethnographic Study Of “Makers” In Fablabs In Japan, Vaughn M. Krebs

Theses and Dissertations--Anthropology

“Makers” around the world cohere in a digital and physical network of technology hobbyists. “Makers" are open-source hardware enthusiasts who use machines like 3D printers and laser cutters - manufacturing tools that have only recently become accessible to laypeople - to make things. “Makers" share a vision for a world where everyone would be able to make almost anything, supplanting top-down economic systems and channels of production. This ethnographic research examines a subset of the “maker” community: “makers” in “FabLabs” in Japan. These “FabLabs” are small workshops that house the machines that “makers” need and make them open to the …

Bioeconomic Analysis Of Engraulicypris Sardella (Usipa) In South East Arm Of Lake Malawi, Innocent Gumulira, Graham E. Forrester, Najih Lazar

Natural Resources Science Faculty Publications

Usipa Engraulicypris sardella is the most abundant small pelagic species in Lake Malawi. It plays an important part in the lake communities’ economy and food security. However, much remains unknown on their stock status and bioeconomic importance. This study is carried out to estimate the maximum economic yield and maximum sustainable yield for Usipa fishery in the South-east arm of Lake Malawi. Structured quantitative questionnaire was used to collect information from 139 informants on the price of usipa landings and cost of fishing effort. Catch and effort data for Usipa were used in a biomass dynamic model (ASPIC) to estimate …

Hemen Mazumdar: The Last Romantic, Caterina Corni, Nirmalya Kumar

Research Collection Lee Kong Chian School Of Business

Hemendranath Mazumdar, popularly referred to as Hemen Mazumdar, was born 1894 in Gachihata village of Mymensingh district, which is currently part of Bangladesh. Coming from a relatively wealthy landowning family, at the age of sixteen, Hemen dropped out of school and ran away to Calcutta to pursue his passion for painting. He enrolled at the Government College of Art in 1911, but left in 1912 for another institution, Jubilee Art Academy. By 1915, he left Jubilee Art Academy to start earning his living through portrait painting. Abanindranath Tagore’s coterie had banished any artist following the western academic approach. In response, …

Ecological Rationality: Fast-And-Frugal Heuristics For Managerial Decision Making Under Uncertainty, Shenghua Luan, Jochen Reb, Gerd Gigerenzer

Research Collection Lee Kong Chian School Of Business

Heuristics are often viewed as inferior to “rational” strategies that exhaustively search and process information. Introducing the theoretical perspective of ecological rationality, we challenge this view and argue that under conditions of uncertainty common to managerial decision making, managers can actually make better decisions using fast-and-frugal heuristics. Within the context of personnel selection, we show that a heuristic called Δ-inference can more accurately predict which of two job applicants would perform better in the future than logistic regression, a prototypical rational strategy. Using data from 236 applicants at an airline company, we demonstrate in Study 1 that despite searching less …

Situational Judgment Tests As Measures Of 21st Century Skills: Evidence Across Europe And Latin America, Christoph Herde, Filip Lievens, Emily G. Solberg, Harbaugh Jan L., Mark H. Strong, Gary J. Burkholder

Research Collection Lee Kong Chian School Of Business

Over the years, various governmental, employment, and academic organizations have identified a list of skills to successfully master the challenges of the 21st century. So far, an adequate assessment of these skills across countries has remained challenging. Limitations inherent in the use of self-reports (e.g., lack of self-insight, socially desirable responding, response style bias, reference group bias, etc.) have spurred on the search for methods that could complement or even substitute self-report inventories. Situational judgment tests (SJTs) have been proposed as one of the complements/alternatives to the traditional self-report inventories. SJTs are low-fidelity simulations that confront participants with multiple domain-relevant …

Intensive Pre-Processing Of Kdd Cup 99 For Network Intrusion Classification Using Machine Learning Techniques, Ibrahim M. Obeidat, Nabhan Hamadneh, Mouhammd Alkasassbeh, Mohammad Almseidin, Mazen Ibrahim Alzubi

All Works

© 2019, International Association of Online Engineering. Network security engineers work to keep services available all the time by handling intruder attacks. Intrusion Detection System (IDS) is one of the obtainable mechanism that used to sense and classify any abnormal actions. Therefore, the IDS must be always up to date with the latest intruder attacks signatures to preserve confidentiality, integrity and availability of the services. The speed of the IDS is very important issue as well learning the new attacks. This research work illustrates how the Knowledge Discovery and Data Mining (or Knowledge Discovery in Databases) KDD dataset is very …

Finite Integration Method With Chebyshev Expansion For Finding Numerical Solution Of Nonlinear And Fractional Order Differential Equations, Ampol Duangpan

Chulalongkorn University Theses and Dissertations (Chula ETD)

In this dissertation, we develop the finite integration method by using Chebyshev polynomial expansion (FIM-CPE) for solving one- and two-dimensional nonlinear differential equations. The developed FIM-CPE can be used on any domains. Then, we utilize our FIM-CPE to deal with the spatial variable and the forward difference quotient to handle the derivative involving temporal variable. Thus, the numerical algorithms based on this idea are devised to overcome three nonlinear problems including one-dimensional Burgers' equation with shock wave, time-fractional Benjamin-Bona-Mahony-Burgers' equation and two-dimensional nonlinear Poisson equation over irregular domains. Moreover, we examine our algorithms with several experimental examples by comparing the …

The Use Of Management Control Systems In Social Enterprises, Varaporn Pothipala

Chulalongkorn University Theses and Dissertations (Chula ETD)

Social Enterprises (SEs) have progressively grown, filling gaps where government and the market fail; that is, when public-sector goods/services are unsatisfactory to support social needs, and for-profit organizations cannot make sufficient profit in providing those goods/services (Austin, Stevenson, & Wei-Skillern, 2006; Haugh, 2005). SEs have emerged to tackle persistent and complex social problems. In Southeast Asia, many social problems (i.e. poverty, unemployment, social and economic inequality) have long been recognised and they persist overtime, especially since the Asian financial crisis in 1997, with SE being introduced in Southeast Asia after the crisis (Defourny & Kim, 2011; Kerlin, 2010). SEs are …

Optimized Light Sources For Enhancing Color Discrimination In People With Low Vision, Anukul Radsamrong

Chulalongkorn University Theses and Dissertations (Chula ETD)

This research was divided into 2 parts. The aim of the first part was to investigate if illuminance level and correlated color temperature (CCT) had an effect on mobility performance in people with low vision compared to the elderly wearing simulated low vision glasses and the elderly with naked eyes. We also compared their mobility in pouring liquid to a specified level. The second part’s aim was to optimize combinations of light emitting diode (LED) channels that increased the discrimination of color in people with low vision. The research procedure of the first part involved 7 lighting conditions, with different …

Akt Expression And Lactose Synthesis During Heat Exposure In Saanen Goat, Nungnuch Saipin

Chulalongkorn University Theses and Dissertations (Chula ETD)

In tropical countries, high ambient temperature (HTa) is a fundamental factor that cause a decline in the mammary gland function in dairy animals. Dairy animals fed under HTa decreased milk yield (MY) as well as milk compositions. The current study focuses on the effect of HTa to decrease milk synthesis from natural and in vitro HTa condition. The first experiment was performed to investigate the effect of HTa from the natural condition in early lactating Saanen goat, 2-4 weeks of postpartum (2 PP-4 PP). Five animals were investigated during the winter season as control ambient condition. Six animals as the …

Studies Of Beta-Cardiotoxin From King Cobra Venom On Rat Cardiac Functions: Effect On Isolated Single Cardiomyocyte, Tuchakorn Lertwanakarn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Beta-cardiotoxin (ß-CTX), a novel protein isolated from the King cobra (Ophiophagus hannah) venom has previously been proposed as a beta-blocker candidate. However, cellular mechanisms of ß-CTX on cardiomyocyte is unknown. This study aimed to evaluate the impact of ß-CTX on isolated rat cardiomyocyte function and the cardiac myofibrillar activity, and to explore involvement of ß-adrenergic receptor (ß-AR) signaling pathway. ß-CTX was isolated and purified using two-step chromatographic method and confirmed by N-terminal sequencer. The function of ß-CTX on cardiomyocyte was compared to propranolol in 3 conditions, basal state, with isoproterenol (ISO), and with forskolin (FSK). ß-CTX exhibited more potency than …

The Left Ventricular Functions And Heart Rate Variability In Dogs With Pulmonic Valvular Stenosis, Ploypanut Trikhun

Chulalongkorn University Theses and Dissertations (Chula ETD)

Pulmonic valvular stenosis (PS) is one of the most common congenital heart diseases in dogs that can lead to the cardiac maladaptation. Also, PS can affect the cardiac autonomic nervous system (ANS). However, clinical information regarding to systolic function and cardiac ANS alteration in PS dogs had not been fully elucidated. The objectives of this study were to evaluate cardiac electrical property, left ventricular (LV) function, and to assess cardiac ANS from heart rate variability (HRV) analysis in PS dogs compared with healthy dogs. The dogs in this study were divided into 2 groups, PS dogs (n=13) and healthy control …

Adjustment Of Maximum Likelihood Method For Multivariate Fay-Herriot Model, Annop Angkunsit

Chulalongkorn University Theses and Dissertations (Chula ETD)

The most widely used area-level model in small area estimation is the Fay-Herriot model, proposed by Fay and Herriot. It was used first to estimate average per capita income for small places (population less than 1,000) of the USA. In the context of the Fay-Herriot model, the traditional method in obtaining estimation of the population mean is the empirical best linear unbiased prediction (EBLUP) estimator. The estimate can be expressed as a weighted sum of the direct survey estimator and regression estimator. One problem that has received attention is the estimation of variance of the area random effects in the …

Automatic Model Identification For Time Series Analysis Using Deep Learning, Paisit Khanarsa

Chulalongkorn University Theses and Dissertations (Chula ETD)

Most time series data can be characterized by a linear process via the autoregressive integrated moving average model requiring a three-component vector which are the autoregressive, differencing, and moving average orders before fitting coefficients. A model identification which determines those orders is analyzed via the partial autocorrelation function to identify the autoregressive order, the autocorrelation function to identify the moving average order and an extended sample autocorrelation function to identify both orders which is a challenging problem for statisticians. Accordingly, the auto-ARIMA model was proposed to automatically vary those orders and estimates their corresponding coefficients. This thesis proposes three architectures …

Bayesian Models For Poverty Mapping In Thailand, Sarasinee Somjettana

Chulalongkorn University Theses and Dissertations (Chula ETD)

Poverty maps are important sources of information for solving social, economic, and environmental problems. Initially, the World Bank used the ELL method to produce poverty maps for used in designing, targeting, prioritizing interventions and allocating the budgets for underdeveloped countries. Even though the ELL method has been shown to have many advantages in poverty mapping, it does not use a survey for the most benefit. Therefore, the Empirical Bayes (EB) method and the hierarchical Bayes (HB) method were proposed in literature. In another aspect, Louis shows that the usual Bayes has a limitation. Therefore, he proposed a new method called …

Self-Balancing Recursive Partitioning Algorithm For Classification Problems, Artit Sagoolmuang

Chulalongkorn University Theses and Dissertations (Chula ETD)

Creating an effective classification model has been played an important role in knowledge discovery in a database methodology for the past several years. However, there is a critical issue that significantly affects the classification performance appearing in many real-world situations, which is called a class imbalanced problem. In this dissertation, a classification model built based on the recursive partitioning algorithm is improved under the concept of modified entropy components for handling a classification problem regardless of the class imbalanced situation. Three methodologies are introduced for achieving different purposes. The first methodology is presented to classify a binary-class imbalanced dataset dealing …

Stochastic Differential Equation With Jumps For Tilapia Population, Kanitin Sukchum

Chulalongkorn University Theses and Dissertations (Chula ETD)

Tilapia population with harvesting in the tilapia farm can be modeled by an ordinary differential equation (ODE). In real life, tilapia population can be affected by many factors. To make the model for tilapia population more realistic, we develop the ODE into the stochastic differential equation (SDE) together with jumps that represent the epidemic occuring for tilapia. Furthermore, we study the effect of some important parameters in the model to the number of tilapia in the tilapia farm via simulation. Both SDEs for tilapia population with and without jumps are simulated by using Euler-Maruyama and jump-adapted Euler methods.

Integer-Valued Time Series Risk Model With Surrender And Investment, Nuntanut Foosarmpok

Chulalongkorn University Theses and Dissertations (Chula ETD)

In this study, we construct the discrete-time risk models based on integer-valued time series models by incorporating the concepts of surrender and investment. The surrender considered in this study is the situation that the policyholder decides to exit the policy before maturity date. In our study, we provide the probabilistic properties of the model. Moreover, we derive approximation of ruin probabilities of the constructed risk model. Finally, we discuss the trends of the ruin probability and the value at risk of the model by numerical simulations.

Text Localization And Extraction From Background With Texture And Noise In Digital Images Using Adaptive Thresholding And Convolutional Neural Network, Pukjira Pattaranuprawat

Chulalongkorn University Theses and Dissertations (Chula ETD)

For the past few years, research topics on finding position of text have received more and more attention from researchers because there are still lots of problems that are needed to be solven. We propose a novel method to find the position of text in an image. The first step of the proposed method is to adjust an image by converting a color image to a gray scale image and then use an average filter to improve an image. An average filter is used to make the background smooth and reduce noise. After that an adaptive thresholding is used to …

Iterative Jump To Binding Point For Simplex Method, Rujira Visuthirattanamanee

Chulalongkorn University Theses and Dissertations (Chula ETD)

The basic idea of an iterative jump method is moving a feasible point along the direction that improves the objective value maintaining the feasibility. It is applied for solving a linear programming (LP) model without artificial variables by applying the iterative jump on the LP relaxation having only acute constraints with respect to the objective direction and reinsert all non-acute constraints to find the optimal solution which is named SAJS. However, it may cause the last jump point to locate far away from the optimal solution so another approach for initially finding a suitable starting point is proposed. The new …

First Order Integer-Valued Autoregressive Model With A Two-Parameter Generalized Poisson-Lindley Distribution, Suchiraporn Bunyaris

Chulalongkorn University Theses and Dissertations (Chula ETD)

In this study, we introduce the first order integer-valued autoregressive models for count data with the two-parameter generalized Poisson-Lindley distribution. The thinning operators considered in this study are the binomial and negative binomial thinning operators. Some important probabilistic and statistical properties such as moments, stationarity and autocorrelation functions are derived. Moreover, parameter estimations and numerical simulations to examine the constructed model are performed. Finally, applications of the models for real data sets are also discussed.

Graph Representation For Room Layout Matching Using Spectral Embedding, Thamonwan Sa-Ngawong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Graph matching is efficient to search similar layout when the architectural floor plan data size is increasing. Because the computational time of floor plan matching using spectral embedding is only in seconds, so it is one of the popular methods. However, the isomorphism of each floor plan leads to low accuracy in the matching process and it becomes the weakness of this method. Therefore, we propose a graph representation for room layout matching using spectral embedding. Normally, graph representations of the floor plan define nodes as rooms and edges as connections between rooms. Besides, the graph spectral embedding is to …

Architectural Joinery Design To Prevent Water Leakage In A Precast Concrete Detached House, Prokchol Vataniyobol

Chulalongkorn University Theses and Dissertations (Chula ETD)

The precast concrete construction is widely used in Thailand by customers and developers for residential development. For many decades of building with the precast concrete wall system, the common problems of water leakage are the most pressing concerns. This thesis aims to find the issues that lead to the causes of water penetration and propose a solution to prevent water leakage. From the literature review, the sources of water leakage are at the connection location between the precast modules. The water can penetrate through the opening with the four forces: a momentum of the raindrop, capillary action, gravity, and air …

Co-Expression Of Feedback Resistant Enzymes In Phenylalanine Biosynthesis Pathway To Increase Phenylalanine Production, Charintip Yenyuvadee

Chulalongkorn University Theses and Dissertations (Chula ETD)

L-Phenylalanine (L-Phe) is an important commercial amino acid. It is widely used in food and pharmaceutical industries. Currently, the requirement of L-Phe is increased according to the great demand for the low-calorie sweetener, aspartame. In Escherichia coli, the synthesis of L-Phe is controlled by the multi-hierarchical regulations. AroG isoform of 3-deoxy- D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) and chorismate mutase/prephenate dehydratase (PheA), two important enzymes, are feedback inhibited by LPhe. Co-expression of feedback-resistant pheA (pheA[superscript L359D]) with other pivotal genes in L-Phe biosynthesis pathway: aroB, aroL, phedh, tktA, aroG, pheA, yddG, and glpF in pRSFDuet-1 (pPTFBLYA[superscript L359D]) elevated L-Phe production of E. …