Digital Commons Network^™

Respiratory Viral Surveillance Of Healthcare Personnel And Patients At An Adult Long-Term Care Facility, Caroline A O'Neil, Lindsay Kim, Mila M Prill, H Keipp Talbot, Brett Whitaker, Senthilkumar K Sakthivel, Yange Zhang, Jing Zhang, Suxiang Tong, Nimalie Stone, Shikha Garg, Susan I Gerber, Hilary M Babcock

Open Access Publications

We conducted active surveillance of acute respiratory viral infections (ARIs) among residents and healthcare personnel (HCP) at a long-term care facility during the 2015-2016 respiratory illness season. ARIs were observed among both HCP and patients, highlighting the importance of including HCP in surveillance programs.

The Impact Of Surgeon Volume And Training Status On Implant Alignment In Total Knee Arthroplasty, Gregory S Kazarian, Charles M Lawrie, Toby N Barrack, Matthew J Donaldson, Gary M Miller, Fares S Haddad, Robert L Barrack

Open Access Publications

BACKGROUND: Implant malalignment may predispose patients to prosthetic failure following total knee arthroplasty (TKA). A more thorough understanding of the surgeon-specific factors that contribute to implant malalignment following TKA may uncover actionable strategies for improving implant survival. The purpose of this study was to determine the impact of surgeon volume and training status on malalignment.

METHODS: In this retrospective multicenter study, we performed a radiographic analysis of 1,570 primary TKAs performed at 4 private academic and state-funded centers in the U.S. and U.K. Surgeons were categorized as high-volume (≥50 TKAs/year) or low-volume (<50 TKAs/year), and as a trainee (fellow/resident under the supervision of an attending surgeon) or a non-trainee (attending surgeon). On the basis of these designations, 3 groups were defined: high-volume non-trainee, low-volume non-trainee, and trainee. The postoperative medial distal femoral angle (DFA), medial proximal tibial angle (PTA), and posterior tibial slope angle (PSA) were radiographically measured. Outlier measurements were defined as follows: DFA, outside of 5° ± 3° of valgus; PTA, >±3° deviation from the neutral axis; and …

Developmental Pathology Of Congenital Kidney And Urinary Tract Anomalies, Sanjay Jain, Feng Chen

Open Access Publications

No abstract provided.

Card And Rbpa Modify The Kinetics Of Initial Transcription And Slow Promoter Escape Of The Mycobacterium Tuberculosis Rna Polymerase, Drake Jensen, Ana R. Manzano, Christina L. Stallings, Eric A. Galburt

Open Access Publications

No abstract provided.

Dietary Pattern And Risk Of Multiple Myeloma In Two Large Prospective Us Cohort Studies, Dong Hoon Lee, Teresa T. Fung, Fred K. Tabung, Graham A. Colditz, Irene M. Ghobrial, Bernard A. Rosner, Edward L. Giovannucci, Brenda M. Birmann

Open Access Publications

No abstract provided.

Complementary Roles Of Pif1 Helicase And Single Stranded Dna Binding Proteins In Stimulating Dna Replication Through G-Quadruplexes, Melanie A. Sparks, Saurabh P. Singh, Peter M. Burgers, Roberto Galletto

Open Access Publications

No abstract provided.

Are The Intrinsically Disordered Linkers Involved In Ssb Binding To Accessory Proteins?, Min Kyung Shinn, Alexander G. Kozlov, Bihn Nguyen, Wlodek M. Bujalowski, Timothy M. Lohman

Open Access Publications

No abstract provided.

Test–Retest Performance Of A 1-Hour Multiparametric Mr Image Acquisition Pipeline With Orthotopic Triple-Negative Breast Cancer Patient-Derived Tumor Xenografts, Xia Ge, James D. Quirk, John A. Engelbach, G. Larry Bretthorst, Shunqiang Li, Kooresh I. Shoghi, Joel R. Garbow, Joseph J.H. Ackerman

Open Access Publications

No abstract provided.

Association Between Rotator Cuff Muscle Size And Glenoid Deformity In Primary Glenohumeral Osteoarthritis, Alexander W Aleem, Peter N Chalmers, Daniel Bechtold, Adam Z Khan, Robert Z Tashjian, Jay D Keener

Open Access Publications

BACKGROUND: Although glenoid morphology has been associated with fatty infiltration of the rotator cuff in arthritic shoulders, the association of rotator cuff muscle area with specific patterns of glenoid wear has not been studied. The purpose of our study was to assess the associations of glenoid deformity in primary glenohumeral osteoarthritis and rotator cuff muscle area.

METHODS: A retrospective study of 370 computed tomographic (CT) scans of osteoarthritic shoulders was performed. Glenoid deformity according to the modified Walch classification was determined, and retroversion, inclination, and humeral-head subluxation were calculated using automated 3-dimensional software. Rotator cuff muscle area was measured on …

Pathogen-Negative Sepsis—An Opportunity For Antimicrobial Stewardship, Gabriel C. Lockhart, Jacob Hanin, Scott T. Micek, Marin H. Kollef

Open Access Publications

No abstract provided.

Comparison Of The Clinical Characteristics Of Hospital-Acquired And Non-Hospital-Acquired Acinetobacter Calcoaceticus-Baumannii Complex In A Large Midwest Us Health Care System, Juan J. Calix, Jason P. Burnham, Mario F. Feldman

Open Access Publications

No abstract provided.

Interdisciplinary Handover Between Obstetric Nursing And Neonatal Physician Teams: An Observational Study, Anshul Arora, Thomas Kannampallil, Joanna Abraham

Open Access Publications

Objective: We investigated the content and quality of communication of interservice interprofessional handover between obstetric nurses and neonatal physicians for high-risk deliveries.

Design: Observational study.

Setting: Labour and delivery unit at a tertiary care hospital.

Method: We audio-recorded handovers between obstetric and neonatal teams (n=50) and conducted clinician interviews (n=29). A handover content framework was developed and used to qualitatively code missing core and ancillary content and their potential for adverse events.

Results: 26 (52%) handovers missed one or more clinical content elements; a third of the handovers missed at least one core clinical content element. Increase in the number …

Temperament And Character Profiles Of Medical Students Associated With Tolerance Of Ambiguity And Perfectionism, Janni Leung, C Robert Cloninger, Barry A Hong, Kevin M Cloninger, Diann S Eley

Open Access Publications

Background: Certain personal attributes, such as perfectionism and tolerance of ambiguity, have been identified as influential in high achieving students. Medical students have been identified as high achievers and perfectionistic, and as such may be challenged by ambiguity. Medical students undertake a long and challenging degree. Personality has been shown to influence the well-being and coping and may equip some students to better cope with challenges. This paper examines the association between temperament and character personality profiles with measures of tolerance of ambiguity and with both adaptive and maladaptive constructs of perfectionism.

Methods: A self-report questionnaire collected data on a …

Understanding The Experience Of Psychopathology After Intimate Partner Violence: The Role Of Personality, Paulo A S Moreira, Márcia Pinto, C. Robert Cloninger, Daniela Rodrigues, Carlos Fernandes Da Silva

Open Access Publications

Objectives: To fully understand the dynamics of Intimate Partner Violence (IPV) it is necessary to understand the role of personality. The current understanding of which personality characteristics are associated with IPV victimization is, however, far from comprehensive. Given this gap in the literature, our objective was to examine the associations between the dimensions of the psychobiological model of personality and psychopathological symptoms in women who had experienced IPV.

Methods: Using a case-control design, a group of women who had experienced IPV and who were living in shelters (

Results: Victims of IPV showed significantly higher levels of Harm Avoidance and …

Npy2r Signaling Gates Spontaneous And Mechanical, But Not Thermal, Pain Transmission, Sihan Chen, Xian-Yu Liu, Yingfu Jiao, Zhou-Feng Chen, Weifeng Yu

Open Access Publications

No abstract provided.

Comparative Genomic Analysis Of Six Glossina Genomes, Vectors Of African Trypanosomes, Geoffrey M. Attardo, Patrick Minx, Chad Tomlinson, Wesley C. Warren, Richard K. Wilson, Et Al

Open Access Publications

No abstract provided.

Rag-Mediated Dna Breaks Attenuate Pu.1 Activity In Early B Cells Through Activation Of A Spic-Bclaf1 Complex, Deepti Soodgupta, Lynn S. White, Wei Yang, Rachel Johnston, Jared M. Andrews, Masako Kohyama, Kenneth M. Murphy, Nima Mosammaparast, Jacqueline E. Payton, Jeffrey J. Bednarski

Open Access Publications

No abstract provided.

Amigo2 Scales Dendrite Arbors In The Retina, Florentina Soto, Nai-Wen Tien, Anurag Goel, Lei Zhao, Philip A. Ruzycki, Daniel Kerschensteiner

Open Access Publications

No abstract provided.

Nix-Mediated Mitophagy Promotes Effector Memory Formation In Antigen-Specific Cd8+ T Cells, Shubhranshu S. Gupta, Robert Sharp, Colby Hofferek, Le Kuai, Gerald W. Dorn Ii, Jin Wang, Min Chen

Open Access Publications

No abstract provided.

Imaging Biomarkers Of Adiposity And Sarcopenia As Potential Predictors For Overall Survival Among Patients With Endometrial Cancer Treated With Bevacizumab, J. Gillen, K. A. Mills, J. Dvorak, B. Zheng, T. Thai, R. Salani, C. M. Cosgrove, B. Davidson, P. H. Thaker, K. N. Moore

Open Access Publications

No abstract provided.

Factors Influencing Residents’ Interest In Gynecologic Oncology Fellowship, Marguerite Palisoul, Molly Greenwade, Leslie S. Massad, Andrea Hagemann, Matthew Powell, David Mutch, Candice Woolfolk, Lindsay Kuroki

Open Access Publications

No abstract provided.

Mouse Model Recapitulates The Phenotypic Heterogeneity Of Human Adult T-Cell Leukemia/Lymphoma In Bone, Nicole A. Kohart, Said M. Elshafae, Wachirapan Supsahvad, Aylin Alasonyalilar-Demirer, Amanda R. Panfil, Jingyu Xiang, Wessel P. Dirksen, Deborah J. Veis, Patrick L. Green, Katherine N. Weilbaecher, Thomas J. Rosol

Open Access Publications

No abstract provided.

Multiple Changes Underlie Allelic Divergence Of Cup2 Between Saccharomyces Species, Xueing C. Li, Justin C. Fay

Open Access Publications

No abstract provided.

Anchor Surgeon Views Of Patient Selection And Expectations For Periacetabular Osteotomy, Adam I. Edelstein, Karen Kaiser Tegal, Sara Shaunfield, Anchor Group, John C. Clohisy, Michael D. Stover

Open Access Publications

No abstract provided.

Complications Associated With Combined Surgical Hip Dislocation And Periacetabular Osteotomy For Complex Hip Deformities, Adam I. Edelstein, Stephen T. Duncan, Sean Akers, Gail Pashos, Perry L. Schoenecker, John C. Clohisy

Open Access Publications

No abstract provided.

Microglia Drive Apoe-Dependent Neurodegeneration In A Tauopathy Mouse Model, Yang Shi, Melissa Manis, Justin Long, Kairuo Wang, Patrick M. Sullivan, Javier Remolina Serrano, Rosa Hoyle, David M. Holtzman

Open Access Publications

No abstract provided.

Perspectives Of United States–Based Infectious Diseases Physicians On Outpatient Parenteral Antimicrobial Therapy Practice, Yasir Hamad, Michael A. Lane, Susan E. Beekmann, Philip M. Polgreen, Sara C. Keller

Open Access Publications

No abstract provided.

Neutralizing Antibodies Against Mayaro Virus Require Fc Effector Functions For Protective Activity, James T. Earnest, Katherine Basore, Vicky Roy, Adam L. Bailey, David Wang, Galit Alter, Daved H. Fremont, Michael S. Diamond

Open Access Publications

No abstract provided.

Rory Regulates The Nlrp3 Inflammasome, Cyrielle Billon, Meghan H. Murray, Amer Avdagic, Thomas P. Burris

Open Access Publications

No abstract provided.

Thiol Isomerase Erp57 Targets And Modulates The Lectin Pathway Of Complement Activation, Oskar Eriksson, Joyce Chiu, Philip J. Hogg, John P. Atkinson, M. Kathryn Liszewski, Robert Flaumenhaft, Bruce Furie

Open Access Publications

No abstract provided.