Digital Commons Network^™

Musineon Glaucescens (Apiaceae), A New Species From Central Montana, U.S.A., Peter Lesica

Biological Sciences Faculty Publications

Musineon glaucesens is described as a new species from two populations in the Big Belt Mountains of Montana, U.S.A. It appears to be most closely allied to the small genus Musineon which is endemic to western North America. It occurs just outside the range of M. vaginatum but differs from that species by its larger fruits, more widely lobed and glaucous leaves, and talus-slope habitat.

Yale Medicine Magazine, Summer 2019, Yale University. School Of Medicine

Yale Medicine Magazine - alumni bulletin and magazine

This is the Summer 2019 issue of Yale Medicine Magazine, v. 53, no. 3. Prepared in cooperation with the alumni and development offices at the School of Medicine. Earlier volumes are called Yale School of Medicine alumni bulletins, dating from v.1 (1953) through v.13 (1965) and Yale Medicine: alumni bulletin of the School of Medicine, v.1 (1965) through v. 52, no.1. (Autumn, 2017).

Gut Yeasts Do Not Improve Desiccation Survival In Drosophila Melanogaster, Joanne M. Tang, Yanira Jiménez Padilla, Marc-André Lachance, Brent J. Sinclair

Biology Publications

A healthy gut microbiota generally improves the performance of its insect host. Although the effects can be specific to the species composition of the microbial community, the role of gut microbiota in determining water balance has not been well explored. We used axenic and gnotobiotic (reared with a known microbiota) Drosophila melanogaster to test three hypotheses about the effects of gut yeasts on the water balance of adult flies: 1) that gut yeasts would improve desiccation survival in adult flies; 2) that larval yeasts would improve adult desiccation survival; 3) that the effects would be species-specific, such that yeasts closely …

Macaque Anterior Cingulate Cortex Deactivation Impairs Performance And Alters Lateral Prefrontal Oscillatory Activities In A Rule-Switching Task, Liya Ma, Jason L. Chan, Kevin Johnston, Stephen G. Lomber, Stefan Everling

Brain and Mind Institute Researchers' Publications

© 2019 Ma et al. In primates, both the dorsal anterior cingulate cortex (dACC) and the dorsolateral prefrontal cortex (dlPFC) are key regions of the frontoparietal cognitive control network. To study the role of the dACC and its communication with the dlPFC in cognitive control, we recorded local field potentials (LFPs) from the dlPFC before and during the reversible deactivation of the dACC, in macaque monkeys engaging in uncued switches between 2 stimulus-response rules, namely prosaccade and antisaccade. Cryogenic dACC deactivation impaired response accuracy during maintenance of—but not the initial switching to—the cognitively demanding antisaccade rule, which coincided with a …

Transcriptomics Of Female Golden Tilefish (Lopholatilus Chamaeleonticeps) Collected Aboard Multiple R/V Weatherbird Ii Cruises In The Gulf Of Mexico From 2015-08-15 To 2016-09-09, Steven Murawski, Kristina Deak, Larry Dishaw

C-IMAGE data

This dataset contains transcriptomics of female golden tilefish (Lopholatilus chamaeleonticeps) collected from the Gulf of Mexico aboard R/V Weatherbird II cruises WB-1602, WB-1603 and WB-1701 from 2015-08-15 to 2016-09-09. Transcriptome analysis was performed in fifteen female (by macroscopic gonad evaluation) golden tilefish livers collected during 2015-2016 C-IMAGE demersal longline cruises in the Gulf of Mexico. These fish were caught at three stations, including one impacted by the Deepwater Horizon spill in the northern Gulf, one within the Campeche Bay oil fields, and one offshore the Yucatan peninsula, with no surrounding oil extraction activity. Differential gene expression between stations was evaluated …

Can A Distant Relative Allow The Government Access To Your Dna? The Fourth Amendment Implications Of Law Enforcement’S Genealogical Search For The Golden State Killer And Other Genetic Genealogy Investigations, George M. Dery Iii

UC Law Science and Technology Journal

This Article considers the advent of genetic genealogy, used by law enforcement in capturing the Golden State Killer suspect and in other cold cases. In these investigations, police used genetic information obtained from the open source genealogy site, GEDmatch, to build vast family trees spanning the entire country and several generations in order to locate suspects whose DNA matched that left at a crime scene. This Article analyzes the Fourth Amendment implications of government use of such powerful technology to explore such sensitive information as DNA. The conclusion the Supreme Court could reach, should it be called upon to examine …

Southeastern Alumni Magazine- Summer 2019, Southeastern University - Lakeland

Southeastern Alumni Magazine

This issue features alumni from a variety of different colleges.

REMEMBERING DR. JAMES HENNESY As the longest-serving president of Southeastern, Dr. James Hennesy’s tenure included leading the university to gain regional accreditation, several building projects and spiritual revivals on campus.

RAY & JUDY RACHELS: A LIFETIME OF LOVE AND MINISTRY Ray and Judy (Homer) Rachels fondly remember meeting as students at Southeastern and their preparation for ministry.

BRANDON HURST: TREKKING THROUGH LIFE With an adventurer’s spirit, Brandon Hurst ’08 has hiked on both U.S. coasts, mountain climbed around the world and has run ultra marathons.

JAYMI YAMOAH: INSPIRING HOPE THROUGH …

The Rock, Summer 2019 (Vol. 89, No. 1), Whittier College

The Rock

No abstract provided.

Transmission Dynamics Of Toxoplasma Gondii In Arctic Foxes (Vulpes Lagopus): A Long-Term Mark-Recapture Serologic Study At Karrak Lake, Nunavut, Canada, Emilie Bouchard, Stacey A. Elmore, Ray T. Alisauskas, Gustaf Samelius, Alvin A. Gajadhar, Keaton Schmidt, Sasha Ross, Emily J. Jenkins

United States Department of Agriculture Wildlife Services: Staff Publications

Transmission dynamics of Toxoplasma gondii, a parasite of importance for wildlife and human health, are enigmatic in the Arctic tundra, where free-ranging wild and domestic felid definitive hosts are absent and rarely observed, respectively. Through a multiyear mark-recapture study (2011– 17), serosurveillance was conducted to investigate transmission of T. gondii in Arctic foxes (Vulpes lagopus) in the Karrak Lake region, Nunavut, Canada. Sera from adult foxes and fox pups were tested for antibodies to T. gondii by using serologic methods, including the indirect fluorescent antibody test, direct agglutination test, and modified agglutination test. The overall seroprevalence was 39% in adults …

2018-2019 - Graduate Council Annual Report, College Of Graduate And Continuing Studies, East Tennessee State University

Graduate Council Agendas and Minutes

No abstract provided.

Clinical Data: Sources And Types, Regulatory Constraints, Applications., Stanley C Ahalt, Christopher G Chute, Karamarie Fecho, Gustavo Glusman, Jennifer Hadlock, Casey Overby Taylor, Emily R Pfaff, Peter N Robinson, Harold Solbrig, Casey Ta, Nicholas Tatonetti, Chunhua Weng

Faculty Research 2019

Access to clinical data is critical for the advancement of translational research. However, the numerous regulations and policies that surround the use of clinical data, although critical to ensure patient privacy and protect against misuse, often present challenges to data access and sharing. In this article, we provide an overview of clinical data types and associated regulatory constraints and inferential limitations. We highlight several novel approaches that our team has developed for openly exposing clinical data.

Genomic Data Analysis Workflows For Tumors From Patient-Derived Xenografts (Pdxs): Challenges And Guidelines., Xing Yi Woo, Anuj Srivastava, Joel H Graber, Vinod Yadav, Vishal Kumar Sarsani, Allen K. Simons, Glen L Beane, Stephen C. Grubb, Guruprasad Ananda, Rangjiao Liu, Grace Stafford, Jeffrey Chuang, Susan Airhart, Radha Krishna Murthy Karuturi, Joshy George, Carol J Bult

Faculty Research 2019

BACKGROUND: Patient-derived xenograft (PDX) models are in vivo models of human cancer that have been used for translational cancer research and therapy selection for individual patients. The Jackson Laboratory (JAX) PDX resource comprises 455 models originating from 34 different primary sites (as of 05/08/2019). The models undergo rigorous quality control and are genomically characterized to identify somatic mutations, copy number alterations, and transcriptional profiles. Bioinformatics workflows for analyzing genomic data obtained from human tumors engrafted in a mouse host (i.e., Patient-Derived Xenografts; PDXs) must address challenges such as discriminating between mouse and human sequence reads and accurately identifying somatic mutations …

Drug Safety Africa: An Overview Of Safety Pharmacology & Toxicology In South Africa., Brian D Guth, Anne F Grobler, Kendall S Frazier, Andrea Greiter-Wilke, Danuta Herzyk, Tertius A Hough, Asrar Ali Khan, Michael Markert, James D Smith, Karen L. Svenson, Sara Wells, Michael K Pugsley

Faculty Research 2019

This meeting report is based on presentations given at the first Drug Safety Africa Meeting in Potchefstroom, South Africa from November 20-22, 2018 at the North-West University campus. There were 134 attendees (including 26 speakers and 34 students) from the pharmaceutical industry, academia, regulatory agencies as well as 6 exhibitors. These meeting proceedings are designed to inform the content that was presented in terms of Safety Pharmacology (SP) and Toxicology methods and models that are used by the pharmaceutical industry to characterize the safety profile of novel small chemical or biological molecules. The first part of this report includes an …

Circulation, Vol. 24, No. 3, Center For Coastal Physical Oceanography, Eileen Hofmann, Brynn Pecher, Margaret Mulholland

CCPO Circulation

Summer 2019 issue of CCPO Circulation featuring article, "Combining Forces to Understand Harmful Algal Bloom Dynamics," by Eileen Hofmann, Brynn Pecher, and Margie Mulholland.

Longwood Magazine 2019 Summer, Longwood University

Alumni Newsletters & Bulletins

No abstract provided.

Synergistic Anti-Inflammatory Effects And Mechanisms Of Combined Phytochemicals, Lijuan Zhang, Carlos Virgous, Hongwei Si

Human Sciences Faculty Research

The anti-inflammatory effects of phytochemicals, bioactive components from plants having health benefits, have been heavily investigated in the last several decades. However, the gap between the high dosage demands (μM) of phytochemicals in vitro studies and the low bioavailability (nM) of most phytochemicals after consuming relevant foods/supplements in humans undermines the application of these phytochemicals in the prevention of chronic inflammation and its related chronic diseases in humans. One of the approaches to bridging this gap is to combine two or more phytochemicals/foods to synergistically prevent chronic inflammation. While increasing combinations of phytochemicals on anti-inflammation studies have been reported, there …

Uni Schedule Of Classes, Summer 2019, University Of Northern Iowa

UNI Schedule of Classes

A listing and schedule of the courses being taught as well as policies and procedures concerning attending classes at the University of Northern Iowa.

Unexpected Empirical Dependence Of Calf Gender On Insemination Time: System-Based Explanation, Griselda Acosta, Eric Smith, Vladik Kreinovich

Departmental Technical Reports (CS)

To improve the efficiency of artificial insemination, farmers equip cows with sensors, based on which a computer system determines the cow's insemination window. Analysis of the resulting calves showed an unexpected dependence of the calf's gender on the insemination time: cows inseminated earlier in their window mostly gave birth to female calves, while cows inseminated later in their window mostly gave birth to males. In this paper, we provide a general system-based explanation for this phenomenon.

Search, The Jackson Laboratory

Search Magazine

No abstract provided.

Co-Crystal Structure Of The Fusobacterium Ulcerans Ztp Riboswitch Using An X-Ray Free-Electron Laser., Christopher Jones, Brandon Tran, Chelsie Conrad, Jason Stagno, Robert Trachman, Pontus Fischer, Alke Meents, Adrian Ferré-D'Amaré

School of Medicine and Health Sciences Student Works

Riboswitches are conformationally dynamic RNAs that regulate gene expression by binding specific small molecules. ZTP riboswitches bind the purine-biosynthetic intermediate 5-aminoimidazole-4-carboxamide riboside 5'-monophosphate (ZMP) and its triphosphorylated form (ZTP). Ligand binding to this riboswitch ultimately upregulates genes involved in folate and purine metabolism. Using an X-ray free-electron laser (XFEL), the room-temperature structure of the Fusobacterium ulcerans ZTP riboswitch bound to ZMP has now been determined at 4.1 Å resolution. This model, which was refined against a data set from ∼750 diffraction images (each from a single crystal), was found to be consistent with that previously obtained from data collected at …

Gene Co-Expression Analysis Of The Human Substantia Nigra Identifies Bmp2 As A Neurotrophic Factor That Can Promote Neurite Growth In Cells Overexpressing Wild-Type Or A53t Α-Synuclein, Susan R. Goulding, Aideen M. Sullivan, Gerard W. O'Keeffe, Louise M. Collins

Department of Biological Sciences Publications

Introduction: α-synuclein-induced degeneration of dopaminergic neurons has been proposed to be central to the early progression of Parkinson's disease. This highlights the need to identify factors that are neuroprotective or neuroregenerative against α-synuclein-induced degeneration. Due to their potent neurotrophic effects on nigrostriatal dopaminergic neurons, we hypothesized that members of the bone morphogenetic protein (BMP) family have potential to protect these cells against α-synuclein. Methods: To identify the most relevant BMP ligands, we used unbiased gene co-expression analysis to identify all BMP family members having a significant positive correlation with five markers of dopaminergic neurons in the human substantia nigra (SN). …

Making Energy Relevant: The Role Of Free Energy In Introductory Physics, Benjamin D. Geller , '01, A. R. Daane

Physics & Astronomy Faculty Works

Free energy is a non-conserved quantity that is of fundamental importance in biochemistry and sociopolitical discourse, but one that does not often get discussed in introductory physics classrooms. While many canonical representations of energy that are encountered in introductory physics (energy bar charts, energy pie charts, etc.) foster ideas about energy that are productive for learners in a wide range of contexts, they have limited utility in contexts where free energy is an important consideration. In this study, we describe how learners who encounter canonical representations of energy in introductory physics develop a deep conviction that energy is conserved, and …

Beyond Human Rights: The Legal Status Of The Individual In International Law. By Anne Peters. Cambridge, Uk: Cambridge University Press, 2016. Pp. Xxxv, 602. Index, Tara J. Melish

Book Reviews

No abstract provided.

News From Hope College, Volume 51.1: Summer, 2019, Hope College

News from Hope College

No abstract provided.

Can Alternate-Day Statin Regimen Minimize Its Adverse Effects On Muscle And Tendon?: A Systematic Review, Zehra Abdul Muhammad, Tashfeen Ahmad, Naveed Baloch

Section of Orthopaedic Surgery

Objective: To review evidence-based data with respect to safety and efficacy of alternate-day statin therapy in dyslipidaemia compared to the standard daily dose.
Methods: The literature review was conducted at Aga Khan University Hospital, Karachi from July, 2016 to August, 2017. Electronic database search was carried out to compile available literature using PubMed, Excerpta Medica database and Google Scholar. The most relevant evidence-based research articles published over 10 years were selected. The latest search was dated August 03, 2017.
Results: A total of 2,074 articles were initially located. Alternate day statin regimen was reported in 53% of articles. Adverse effects …

Legal Aspects Of Airboats, Robert Jarvis

Faculty Scholarship

No abstract provided.

Competitive Reversal Between Plant Species Is Driven By Species‐Specific Tolerance To Flooding Stress And Nutrient Acquisition During Early Marsh Succession, Andrew Muench, Tracy Elsey‐Quirk, Zhongling Yang

Faculty Publications

No abstract provided.

Improving The Transferability Of Suspended Solid Estimation In Wetland And Deltaic Waters With An Empirical Hyperspectral Approach, Daniel Jensen, Marc Simard, Kyle Cavanaugh, Yongwei Sheng, Cédric G. Fichot, Tamlin Pavelsky, Robert Twilley

Faculty Publications

The deposition of suspended sediment is an important process that helps wetlands accrete surface material and maintain elevation in the face of sea level rise. Optical remote sensing is often employed to map total suspended solids (TSS), though algorithms typically have limited transferability in space and time due to variability in water constituent compositions, mixtures, and inherent optical properties. This study used in situ spectral reflectances and their first derivatives to compare empirical algorithms for estimating TSS using hyperspectral and multispectral data. These algorithms were applied to imagery collected by NASA’s Airborne Visible/Infrared Imaging Spectrometer-Next Generation (AVIRIS-NG) over coastal Louisiana, …

Hepatic Polycyclic Aromatic Hydrocarbons (Pahs) Concentrations In Groupers Collected Aboard Multiple Research And Fishing Vessels In The Gulf Of Mexico From 2011-07-07 To 2017-07-30, Erin Pulster, Justin Mrowicki, Steven A. Murawski, Brigid Carr

C-IMAGE data

This dataset contains hepatic polycyclic aromatic hydrocarbons (PAHs) concentrations in groupers collected aboard multiple research and fishing vessels (R/V Weatherbird II, F/V Brandy, F/V Pisces, F/V SeaFox) in the Gulf of Mexico from 2011-07-07 to 2017-07-30. The dataset contains the location, date, type of grouper, concentrations of various PAHs in liver tissue (ng/g w.w.), and the total or sum of the low and high molecular weight PAHs (ng/g w.w.). PAHs were extracted from homogenized liver tissues using QuEChERS EMR (Agilent Technologies, Bond Elut) and confirmed and quantified using an Agilent’s 7890B gas chromatograph (GC) coupled to a 7010 tandem mass …

Histological Examination Of Livers Of Golden Tilefish (Lopholatilus Chamaeleonticeps) Collected Aboard Multiple R/V Weatherbird Ii Cruises In The Gulf Of Mexico From 2012-08-14 To 2016-09-06, Erin Pulster, S. Fogelson, S. Synder

C-IMAGE data

This dataset contains a histological examination of livers of golden tilefish (Lopholatilus chamaeleonticeps) collected aboard the R/V Weatherbird II cruises WB-1304, WB-1403, WB-1502, WB-1602, WB-1603, and WB-1701 in the Gulf of Mexico from 2012-08-14 to 2016-09-06. The dataset includes the identified presence of histological changes and images of the gross and histological evaluations. Formalin-fixed tissues were individually evaluated for color, texture, size, shape, and consistency. Photographs were taken with a Sony-Cybershot camera (Sony Corporation, Minato, Tokyo, Japan). At least two photographs were taken of the samples from each container. The first photo contained the label along with the tissues from …