Digital Commons Network^™

Optimization And Structural Stability Of Gold Nanoparticle–Antibody Bioconjugates, Robert T. Busch, Farzia Karim, John Weis, Yvonne Sun, Chenglong Zhao

Chemical and Materials Engineering Faculty Publications

Gold nanoparticles (AuNPs) bound with biomolecules have emerged as suitable biosensors exploiting unique surface chemistries and optical properties. Many efforts have focused on antibody bioconjugation to AuNPs resulting in a sensitive bioconjugate to detect specific types of bacteria. Unfortunately, bacteria thrive under various harsh environments, and an understanding of bioconjugate stability is needed. Here, we show a method for optimizing Listeria monocytogenes polyclonal antibodies bioconjugation mechanisms to AuNPs via covalent binding at different pH values, from 2 to 11, and 2-(N-morpholino)ethanesulfonic acid (MES), 3-(N-morpholino)propanesulfonic acid, NaOH, HCl conditions. By fitting Lorentz curves to the amide I and II regions, we …

Antisense Oligonucleotide Modulators Of Serotonin Receptor 2c And Uses Thereof, Stefan Stamm, Manli Shen, Serene Josiah

Molecular and Cellular Biochemistry Faculty Patents

The present invention provides, among other things, oligonucleotide modulators of human 5′-HT2C receptor (HTR2C) and improved methods and composition for treating HTR2C-related diseases, disorders or conditions based on such modulators. In particular, oligonucleotides modulators according to the invention target specific regions in the Exon V/Intron V junction of the human HTR2C pre-mRNA and drive expression of HTR2C Vb splice isoform, leading to increased generation of non-edited strong HTR2C receptor and enhanced serotonin receptor activity.

Freshman Intent On 'Fulfilling Her Purpose', Shea Stewart

University of Mississippi News

Next-Generation Rebels: Biology major Khadeejah Franklin has goals in mind

The Current Volume 30 : Issue 4, Nova Southeastern University

Student Newspapers

No abstract provided.

The Experience Of Cognitive Change In Women With Breast Cancer Following Chemotherapy, Mary Louise Kanaskie

Dissertations

Change in cognitive function is one side effect of chemotherapy that has been reported in some breast cancer survivors. Alarming reports indicate that between 16 to 50 percent of women receiving chemotherapy for breast cancer experience symptoms of cognitive impairment. These symptoms include subtle changes in memory, concentration, and some higher order processes that include psychomotor speed and executive functioning. In addition, it has been reported that these symptoms may persist even years after completion of treatment. Research is limited that has explored the lived experience of the phenomenon of chemotherapy-related cognitive change in breast cancer survivors.

The purpose of …

Post-Stroke Depression Screening And Interventions, Shwetaben Pinak Patel

DNP and Student Works

Post-stroke depression (PSD) is the most commonly seen neuropsychiatric condition in stroke patients' population. Depressive symptoms in addition to the stroke symptoms, patients may have negative outcome with increased morbidity, mortality, and lesser functional recovery. Stroke patients may suffer from depression in acute as well as chronic phases. Early identification of depressive symptoms in outpatient, managing, and help patients overcome from those symptoms are very crucial to achieve positive outcome in stroke patients. To facilitate depression screening at the primary care level one should select a screening tool with high specificity, and validity for this patient population. There should be …

Mouth Function Determines The Shape Oscillation Pattern In Regenerating Hydra Tissue Spheres, R. Wang, T. Goel, K. Khazoyan, Ziad Sabry , '21, H. J. Quan, P. H. Diamond, Eva-Maria S. Collins

Biology Faculty Works

Hydra is a small freshwater polyp capable of regeneration from small tissue pieces and from aggregates of cells. During regeneration, a hollow bilayered sphere is formed that undergoes osmotically driven shape oscillations of inflation and rupture. These oscillations are necessary for successful regeneration. Eventually, the oscillating sphere breaks rotational symmetry along the future head-foot axis of the animal. Notably, the shape oscillations show an abrupt shift from large-amplitude, long-period oscillations to small-amplitude, short-period oscillations. It has been widely accepted that this shift in oscillation pattern is linked to symmetry breaking and axis formation, and current theoretical models of Hydra symmetry …

Sex Differences In Fatigability And Recovery Relative To The Intensity–Duration Relationship, Paul Ansdell, Paul Ansdell, Callum G. Brownstein, Jakob Škarabot, Kristy M. Hicks, Glyn Howatson, Kevin Thomas, Sandra K. Hunter, Stuart Goodall

Exercise Science Faculty Research and Publications

Females are less fatigable than males during isometric exercise at intensities relative to maximal voluntary contraction (MVC); however, whether a sex difference in fatigability exists when exercise is prescribed relative to a critical intensity is unknown. This study established the intensity–duration relationship, and compared fatigability and recovery between sexes following intermittent isometric contractions normalised to critical intensity. Twenty participants (10 females) completed four intermittent isometric knee extension trials to task failure to determine critical intensity and the curvature constant (W′), followed by fatiguing tasks at +10% and −10% relative to critical intensity. Neuromuscular assessments were completed at baseline …

Constructing The Meaning Of Family In The Context Of Biological Family Separation : A Study Of Children In Institutional Care And Care Leavers In Zimbabwe, Getrude Dadirai Gwenzi

Lingnan Theses (MPhil & PhD)

Family has been defined as a powerful and pervasive word in our culture, embracing a variety of social, cultural, economic and symbolic meanings. Its importance for the development and wellbeing of children cannot be overemphasized. How ‘family’ is conceptualized by both children and adults remains a highly-contested subject considering the many changes in the form, structure, and relationships that could be described as ‘family’. Few studies have examined the relational lives of children and young adults who grow up in institutional care from a sociological perspective. The thesis makes meaningful contributions to the literature with a study of children and …

Bright Split Red Fluorescent Proteins For The Visualization Of Endogenous Proteins And Synapses, Siyu Feng, Aruna Varshney, Doris Coto Villa, Cyrus Modavi, John Kohler, Fatima Farah, Shuqin Zhou, Nebat Ali, Joachim D. Müller, Miri Vanhoven, Bo Huang

Faculty Publications, Biological Sciences

Self-associating split fluorescent proteins (FPs) are split FPs whose two fragments spontaneously associate to form a functional FP. They have been widely used for labeling proteins, scaffolding protein assembly and detecting cell-cell contacts. Recently developments have expanded the palette of self-associating split FPs beyond the original split GFP1-10/11. However, these new ones have suffered from suboptimal fluorescence signal after complementation. Here, by investigating the complementation process, we have demonstrated two approaches to improve split FPs: assistance through SpyTag/SpyCatcher interaction and directed evolution. The latter has yielded two split sfCherry3 variants with substantially enhanced overall brightness, facilitating the tagging of endogenous …

My News, Georgia Southern University

My News (2014-2020)

• PwC Network executive to lead this year's Fries Lecture
• Georgia Southern University celebrates Hispanic and Latinx Heritage Month
• Legal Affairs Boot Camp Fall 2019
• 7th annual GreenFest
• Spread the word about the Captain's Cupboard Food Pantry
• Georgia Southern biology graduate students awarded sea grants for research
• Georgia Southern to host STEMFest '19 on Statesboro Campus Sept. 21
• Call for proposals open for 19th annual National Cross-Cultural Counseling and Education Conference for Research, Action and Change
• World Soccer Day, home competitions and military appreciation

Faculty Senate Agenda, Helen Bland

Faculty Senate Agendas

No abstract provided.

Sequencing Heparan Sulfate Using Hilic Lc-Netd-Ms/Ms, Jiandong Wu, Juan Wei, Pradeep Chopra, Geert Jan Boons, Cheng Lin, Joseph Zaia

Chemical and Biochemical Engineering Faculty Research & Creative Works

Heparan Sulfate (HS) Mediates a Wide Range of Protein Binding Interactions Key to Normal and Pathological Physiology. Though Liquid Chromatography Coupled with Mass Spectrometry (LC-MS) based Disaccharide Composition Analysis is Able to Profile Changes in HS Composition, the Heterogeneity of Modifications and the Labile Sulfate Group Present Major Challenges for Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) Sequencing of the HS Oligosaccharides that Represent Protein Binding Determinants. Here, We Report Online LC-MS/MS Sequencing of HS Oligosaccharides using Hydrophilic Interaction Liquid Chromatography (HILIC) and Negative Electron Transfer Dissociation (NETD). a Series of Synthetic HS Oligosaccharides Varying in Chain Length (Tetramers and Hexamers), …

Genesis Of Iron And Manganese Sediments In Zoloushka Cave (Ukraine/Moldova) As Revealed By Δ13C Organic Carbon, Piotr Kotula, Viacheslav Andreychouk, Jacek Pawlyta, Leszek Marynowski, Izabela Jendrzejewska

International Journal of Speleology

Zoloushka Cave is one of the largest maze gypsum caves in the world. Mining of the gypsum bedrock and lowering of the water level due to the pumping of groundwater led to exposure of the cave passages to vadose conditions and changed the hydrochemistry of the karst water. As a result, large quantities of Fe and Mn hydroxides were deposited in the passages. It was found that at least two groups of various organisms were involved in depositing ferrous and manganese sediments. In order to establish the mechanism of deposition, we conducted chemical analyses of the sediments and isotopic analyses …

Academic Skill Learning And The Problem Of Complexity I: Creational Purposeful Integrated Capability At Skill (Cpics), Martin F. Gardiner

Northeast Journal of Complex Systems (NEJCS)

Physical and mental skills are intended to achieve success at acting purposefully. As capability at any skill increases, the need to adjust details of application to complexity of context and goals will increase as well. It will become more and more important to prepare mentally for what I now term Creational Purposeful Integrated Capability at Skill (CPICS). This paper develops what I mean by CPICS. Theory concerning Complex Dynamical Systems (CDS) such as the brain and other evidence points to the likelihood that the mental operations by which our brain produces any kind of skillful behavior cannot remain constant, …

Full Issue

IdeaFest: Interdisciplinary Journal of Creative Works and Research from Cal Poly Humboldt

No abstract provided.

Perceived Effect Of Telemedicine On Medical Service Delivery By Federal Medical Centers In North Central Zone Of Nigeria, Akor Solomon Obotu

Library Philosophy and Practice (e-journal)

The study investigated the perceived effect of telemedicine on medical service delivery by the Federal Medical Centers in North Central Nigeria. Six objectives guided the study. The study answered six research questions and tested two null hypotheses at 0.05 level of significance. The study adopted survey research design. The research was conducted in the North Central Zone of Nigeria. The population of the study was one thousand four hundred and seven (1407) medical staff (Doctors, Nurses, Laboratory Technologists and Pharmacists). The sample size was three hundred and eleven (311) respondents comprising 97 doctors, 178 nurses, 19 laboratory technologists and 17 …

Senior High School Students’ Use Of Library Resources And Services, Dessy Harisanty

Library Philosophy and Practice (e-journal)

Abstract

Purpose – School library plays an important role in meeting the information needs of students. Students of Senior High School require information to support their personal, study, and environmental needs. Therefore, to meet their needs, high school students conduct information seeking. This study aims to determine the information seeking behavior of high school students in Surabaya.

Design/methodology/approach – The method applied in this study is a descriptive quantitative approach. The samples of this study were high school students in Surabaya-East Java-Indonesia, selected by using multistage random sampling. The data collection was conducted through questionnaires. The sample size is 200 …

Evaluation Of Selected Open Access Electronic Thesis And Dissertation Repositories, Javaid Wani, Umer Gull Khan, Aadil Ahmad Hafiz

Library Philosophy and Practice (e-journal)

Abstract

Purpose: The purpose of the study is to evaluate the selected open access electronic thesis and dissertation repositories based on the selected parameters like Visual interface, search features, format, registration and alerting services.

Design/methodology/approach: Survey method coupled with online visits to selected repository websites was carried in order to achieve the objectives of the study.

Findings: The findings show that repositories are having adequate features, but there is a need of improvement also.

Research limitations/implications: The scope of the study is limited to the open access electronic thesis and dissertation repositories of three subject domains viz General Sciences, …

Digital Literacy Among Female Postgraduate Students Of Karnatak University, Dharwad, Karnataka, India: A Study, C Krishnamurthy, Latha Shettappanavar

Library Philosophy and Practice (e-journal)

Digital literacy is the ability of an individual to locate, organize, evaluate, analyze and use the required information using digital technologies. It includes a working knowledge of several technologies and understanding of how it can be used. The main objective of the study was to determine the literacy of using digital resources by Female Postgraduate students of Karnatak University, Dharwad. The present study also determines the student’s level of ICT skills, frequency of internet use by the respondents, ascertain their awareness about different databases and their familiarity with various search strategies to retrieve E-resources. The study also highlights the problems …

Mapping Of The Research Output On ‘Wireless Communication (2010 - 2018)’: A Web Of Science Based Scientometric Evaluation, Padma P (Dr.), Ramasamy K (Dr.)

Library Philosophy and Practice (e-journal)

The present study aimed at examining the quantitative and qualitative aspects of literature output on Wireless Communication as available and indexed in Web of Science database covering a nine year period i.e from 2010 to 2018. A total of 8482 records were downloaded from Web of Science core collection database. The downloaded records, in txt format, were exported to Bibexcel software for analyzing the data for certain quantitative and qualitative indicators. MS Excel programme was used to do all the necessary calculations and preparation of cross tables with Pivot Table options. The findings were presented under the major heads as …

E-Learning Platform In Saarc Countries, Rajesh Das, Uttam Kumar Hazra, Sinjini Mukherjee

Library Philosophy and Practice (e-journal)

The present paper deals with the e-Learning platform in SAARC countries. There are eight SAARC countries (Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan and Srilanka) but among them only 5 countries (Afghanistan, Bangladesh, India, Pakistan and Srilanka) have their own e-learning platform for their citizens.

Purpose: To acquire information about each and every e-learning platform which includes name, year of origin, sponsoring authority, aims, subject area covered, learning path, learning quadrant and type of the courses offered by each e-learning platform.

Methodology: e-Learning platforms of each SAARC countries have been studied and filled a questionnaire. The collected data are tabulated …

Highly Cited Papers In Medical Fields: Scientometric Indicators And Collaboration In Oic Countries, Azadeh Haseli-Mofrad, Maryam Shekofteh, Maryam Kazerani

Library Philosophy and Practice (e-journal)

Some OIC countries have been growing rapidly in terms of international scientific publication.The purpose of this study was to determine the number of highly cited papers, the scholarly impact, H-index, Y-index, and the status of scientific collaboration among Islamic countries in medical fields. The research population included the highly cited papers in medical subject fields of all Islamic countries based on ESI. The Islamic world accounts for 1,338 (2.58%) of the world’s highly cited papers in medical fields, showing a rising trend from 2007–2017. Turkey, Saudi Arabia, and Iran rank first to third, respectively, in terms of the number of …

What Do Agricultural And Biological Science Students Use? A Bibliometric Analysis Of Undergraduate Research Projects, Jerome Idiegbeyan-Ose, Ayooluwa Aregbesola, Sols Owolabi, Toluwani Eyiolorunshe, Ayotunde Owolabi

Library Philosophy and Practice (e-journal)

The study investigate the citation pattern of undergraduate projects in a private university, Nigeria. Bibliometric method was adopted for the study to analyze the information sources cited in the research projects. The coverage of the study was from 2015 to 2018 set of graduates. Findings revealed that Animal Science programme accounted for the highest citations, while Agricultural Economics had the lowest citations. It was also discovered that an average of 49 citations per project were recorded. Journal articles and books were the most cited materials. The paper concluded and made recommendations.

The Effective Factors On Environmentally Friendly Behavior: A Case Study, Mohammad Hassan Seif, Sareh Nematolahi M.A

Library Philosophy and Practice (e-journal)

The interdependence between human and environment manifest the necessity of investigating human impact on environmental degradation or on environmental protection. The present research aims to develop a causal model of effective factors on environmentally friendly behavior among high school students in Shiraz. This is applied research with a descriptive method. Using an adapted questionnaire, we examined the effect of the variables, including environmental concern, attitude, knowledge, subjective norms, responsibility perception, and dependence on nature, on environmentally friendly behavior. The correlation coefficient was used to examine the effect of different variables on each other, and the path analysis method was used …

Differences Between Faculty Members And Research Scholars In Use Of E-Resources, Anil Kumar Siwach

Library Philosophy and Practice (e-journal)

Purpose: The present study investigates the differences between faculty and research scholars in terms of e-resource use, methods of use, purpose, hindrances faced and search strategies.

Methodology: The study was conducted in five universities of North India using survey method. Stratified random sampling was used for selection of the samples and the final data consisted of 668 respondents including 252 faculty members and 416 research scholars. Mann Whitney test was conducted for testing of hypotheses.

Findings: In the study it was found that the faculty members used e-resources more in comparison to the research scholars. Significant differences …

The Evaluation Of Organizational Climate In College Libraries And Its Relation With Clients’ Satisfaction, Farzad Zabani, Maryam Shekofteh (Corresponding Authour), Maryam Kazerani, Farid Zayeri

Library Philosophy and Practice (e-journal)

Purpose: Healthy organizational climate have an important role in the promotion of customer services. The aim of this research is to evaluate the organizational climate of the college libraries and its relation to the clients’ satisfaction.

Methodology: Research population is the staff and the clients of the college libraries of Shahid Beheshti University of Medical Sciences. The climateQUAL questionnaire was used to assess the libraries organizational climate. A researcher-made questionnaire was used to evaluate clients’ satisfaction. Descriptive statistics and Spearman’s correlation coefficient were applied in SPSS 19 for data analysis.

Findings: The organizational climate score of the libraries was more …

Al-Imam Mohammad Ibn Saud Islamic University: A Bibliometric Research Profile, Sulaiman Khalid Al Fouzan, Ikram Ul Haq, Raken Khalid Al Fouzan

Library Philosophy and Practice (e-journal)

Aim: To investigate the status of research productivity and publication trends of Al-Imam Mohammad ibn Saud Islamic University (IMSIU) during the period of 2009 to 2018.

Method: A quantitative and retrospective research method was used. Publications data of IMSIU researchers have been retrieved from Scopus database published during the period of ten years from January 2009 to December 2018. The retrieved dataset has been transferred in Microsoft Excel spreadsheet to analyse the bibliometric indicators, as the growth of publications by year, subject stratification, national and international collaboration, frequently used journals and productive authors.

Results: IMSIU affiliated researchers have produced 2010 …

Library User Education As Panacea To Students Successful Research In Nigerian Universities : A Case Of Federal University Lokoja, Nigeria, Aminu Danbabale, Ayuba Ubale Saad

Library Philosophy and Practice (e-journal)

No abstract provided.

Open Access Resources In Science And Technology: An Overview., Fakrudhin Ali Ahamed H Mr, Anila Sulochana Dr.

Library Philosophy and Practice (e-journal)

Open access resources includes open access archives/repositories, open access journals, open access books, open access search engines and open educational resources etc., the objective of the study is to find open access resources available in Science and Technology. To achieve this objective the investigator visited several Science & Technology University library websites and research organisations websites to locate the resources. In the findings investigator discussed the several resources related to Science and Technology like open DOAR, PubMed Central, arXiv, BioMed Central, DOAJ, Bentham Open, PLOS Journals, Hindawi journals, Springer Open, Wiley open access journals, Science Direct open access journals, NISCAIR …