Digital Commons Network^™

Environmental Degradation And The Legal Imperatives Of Improvement: Forest Policy In Western Australia From European Settlement To 1918, Guy Charlton, Ricardo Napper

The University of Notre Dame Australia Law Review

No abstract provided.

Long-Lasting Insecticide Netting For Protecting Tree Stems From Attack By Ambrosia Beetles (Coleoptera: Curculionidae: Scolytinae), Christopher M. Ranger, Christopher T. Werle, Peter B. Schultz, Karla M. Addesso, Jason B. Oliver, Michael E. Reding

Agricultural and Environmental Sciences Faculty Research

Ambrosia beetles (Coleoptera: Curculionidae: Scolytinae) are destructive wood-boring insects of horticultural trees. We evaluated long-lasting insecticide netting for protecting stems against ambrosia beetles. Container-grown eastern redbud, Cercis canadensis, trees were flood-stressed to induce ambrosia beetle attacks, and deltamethrin-treated netting was wrapped from the base of the stem vertically to the branch junction. Trees were deployed under field conditions in Ohio, Virginia, Tennessee, and Mississippi with the following treatments: (1) flooded tree; (2) flooded tree with untreated netting; (3) flooded tree with treated ‘standard mesh’ netting of 24 holes/cm²; (4) flooded tree with treated ‘fine mesh’ netting of 28 …

Contributions To Variable Selection In Complexly Sampled Case-Control Models, Epidemiology Of 72-Hour Emergency Department Readmission, And Out-Of-Site Migration Rate Estimation Using Pseudo-Tagged Longitudinal Data, Kyle Anderson

Computational and Data Sciences (PhD) Dissertations

This work consists of three different projects.

In the first project, I analyze complexly sampled survey data, representative of the US population, to determine what lifestyle behaviors and notions held by participants are most significant with having had a cancer diagnosis. A logistic regression model was built using automatic variable selection with forward selection with backwards elimination. Our results show that sunscreen usage, level of agreeing with the statement "behaviors can affect high blood pressure", age, intent to eat more or less fruit, average daily hours spent watching tv or playing video games, and level of agreeing with the statement …

Diel Temperature And Ph Variability Scale With Depth Across Diverse Coral Reef Habitats, Tyler Cyronak, Yuichiro Takeshita, Travis A. Courtney, Eric H. Decarlo, Bradley D. Eyre, David I. Kline, Todd R. Martz, Heather Page, Nichole Price, Jennifer Smith, Laura Stoltenberg, Martin Tresguerres, Andreas J. Andersson

Marine & Environmental Sciences Faculty Articles

Coral reefs are facing intensifying stressors, largely due to global increases in seawater temperature and decreases in pH. However, there is extensive environmental variability within coral reef ecosystems, which can impact how organisms respond to global trends. We deployed spatial arrays of autonomous sensors across distinct shallow coral reef habitats to determine patterns of spatiotemporal variability in seawater physicochemical parameters. Temperature and pH were positively correlated over the course of a day due to solar heating and light‐driven metabolism. The mean temporal and spatial ranges of temperature and pH were positively correlated across all sites, with different regimes of variability …

More Than Just Precedent: Perspectives On Judgment Writing, Katrina Banks-Smith

The University of Notre Dame Australia Law Review

No abstract provided.

Habermas And The Question Of Bioethics, Hille Haker

Theology: Faculty Publications and Other Works

In The Future of Human Nature, Jürgen Habermas raises the question of whether the embryonic genetic diagnosis and genetic modification threatens the foundations of the species ethics that underlies current understandings of morality. While morality, in the normative sense, is based on moral interactions enabling communicative action, justification, and reciprocal respect, the reification involved in the new technologies may preclude individuals to uphold a sense of the undisposability (Unverfügbarkeit) of human life and the inviolability (Unantastbarkeit) of human beings that is necessary for their own identity as well as for reciprocal relations. Engaging with liberal …

Miles Article Models Animal Mating Evolution Like Rock, Paper, Scissors, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Thank You, Dad, Eric F. Spina

President's Blog: From the Heart

I have often been accused of being sentimental. In my defense, Italian Catholics are known to be a bit emotional. My eyes well up watching movies, dropping my kids off at college and thinking about what Karen means to me. I plead guilty, unapologetically.

Ohio Researcher Collaborates On Paper On Evolution Of Mating Systems (December 20, 2019), University Communications And Marketing

OHIO News Articles Archive

No abstract provided.

A Drive To Driven Model Of Mapping Intraspecific Interaction Networks., Libo Jiang, Jian Xu, Mengmeng Sang, Yan Zhang, Meixia Ye, Hanyuan Zhang, Biyin Wu, Youxiu Zhu, Peng Xu, Ruyu Tai, Zixia Zhao, Yanliang Jiang, Chuanju Dong, Lidan Sun, Christopher H. Griffin, Claudia Gragnoli, Rongling Wu

Division of Endocrinology, Diabetes and Metabolic Diseases Faculty Papers

Community ecology theory suggests that an individual's phenotype is determined by the phenotypes of its coexisting members to the extent at which this process can shape community evolution. Here, we develop a mapping theory to identify interaction quantitative trait loci (QTL) governing inter-individual dependence. We mathematically formulate the decision-making strategy of interacting individuals. We integrate these mathematical descriptors into a statistical procedure, enabling the joint characterization of how QTL drive the strengths of ecological interactions and how the genetic architecture of QTL is driven by ecological networks. In three fish full-sib mapping experiments, we identify a set of genome-wide QTL …

Food Choice Reform: Shifting American Culture Toward Sustainable Diets, Colleen Mccarthy

Student Theses 2015-Present

Excessive meat consumption is associated with a wide range of environmental problems. Reducing meat consumption has been recognized as one of the most efficient ways to decrease one’s ecological footprint, yet meat consumption is still on the rise and many are not willing to make changes to their diets to include less meat. This paper discusses the problem of America’s continued and rising overconsumption of meat, with the end goal of developing and concluding which strategies are most effective at shifting American culture toward sustainable diets. Chapter 1 gives an overview of why a reduction in meat consumption is necessary …

Holy Cross Magazine, Vol. 54, No. 1, Winter 2020, College Of The Holy Cross

Holy Cross Magazine

Mable Millner Looks Back Over a Career Spent Looking Ahead
As she prepares to retire, Millner talks about bridging gaps, breaking ground and why her work is so much more than a profession.
By Meredith Fidrocki

Syllabus: Economics of Inequality
with Kolleen Rask, professor of economics
By Jane Carlton

Sanctae Crucis 2019
Meet the latest recipients of the College’s highest non-degree alumni honor.

Melissa DeChellis Decided to Amputate Her Right Leg. Here's What Happened Next
A lifetime of chronic pain and injury led her here, even though it meant giving up her dream of being a doctor. But what she …

Design, Synthesis, & Biological Evaluation Of Novel Het-Aromatic/Aromatic Analogs For The Treatment Of Hiv, Cancer, & Cognitive Dysfunctions, Mohit Gupta

Electronic Theses and Dissertations

Cyclophilin A are a class of peptidyl-prolyl isomerases that catalyzes isomerization of the proline residue within a protein. Cyclophilin A plays an instrumental role in the pathogenesis of HIV and HCV virus. Using structure-based drug we designed and synthesized small molecule inhibitors of cyclophilin A. These inhibitors were biologically evaluated for their ability to inhibit WT HIV-1 inhibition.

Mitogen-Activated Protein Kinase signaling cascades plays a critical role in cancer cell survival, metastasis, and chemo-resistance. The MEK5/ERK5 pathway, which is a member of MAPK signaling cascade, is involved in cell survival, anti-apoptotic signaling, angiogenesis, and cell motility. It is found to …

Evaluating Perceptions Of Student Voice And School Membership Of 9th Grade Students And Teachers, Dan Beck

Electronic Theses and Dissertations

Adolescence marks a developmental period of rapid cognitive, emotional, and physical growth where teenagers are tasked with establishing an identity and strong sense of self. Students and parents often report that transition to ninth grade is a formidable social challenge amidst increased academic demands and stress, and some research suggests that females have a more difficult time in the transition to high school than males. Student voice is a range of student opportunities to interact, collaborate, and partner with adults in an exploration of ideas and perspectives. However, student voice opportunities are often only available to a select group of …

Voices On The Horizon: A Theory Of Ludic Rhetoric, Jeff Lohr

Electronic Theses and Dissertations

Voices on the horizon: A theory of ludic rhetoric begins with the assumption that rhetoric and play offer hope for cooperation and community in a fragmented and divided world. Rhetoric and play share an intellectual trajectory in the history of ideas. The earliest use of the terms rhetor and rhetoric in the Western tradition encouraged playful cooperation. The move toward reason and science during the Enlightenment relegated rhetoric to mere techniques for persuasion and silenced alternative avenues for seeking truth. Reclaiming traditional rhetoric as a meeting place for potential negotiation and cooperation encourages constructive civic discourse. The conclusion of this …

A Study Of Chloride Levels In Pine Creek, Allegheny County, Pa, Selina Prettner

Electronic Theses and Dissertations

Pine Creek is a 22.8-mile long tributary to the Allegheny River draining over 67 square miles of northern Allegheny County, PA. The main stem runs along Route 8 and receives extensive runoff from road salt from deicing. A site near Etna, PA sampled biweekly in 2013 consistently showed elevated conductivity that correlated with increased chloride levels. Winter road deicing runoff produced acute chloride concentrations up to 678 mg/L. Chloride fluctuated in the summer and autumn months but did not exceed the USEPA Secondary Drinking Water Standard (250 mg/L) or the aquatic life criterion for chronic concentrations (230 mg/L). Sampling throughout …

The Effect Of Invasive Plants On Soil Microbial Activity In A Ny Temperate Forest, Victoria Dawn Hull

Theses - ALL

Invasive woody plants are often strong competitors that can have large effects on ecosystem function. While there is evidence that Northeastern invasive species can increase nitrogen cycling in monocultures, little is known about how invasive plants alter biogeochemistry in the field. I hypothesized that the high-quality leaf and root litter of invaders would enhance the quality of soil organic matter, leading to greater belowground microbial activity and faster rates of nitrogen mineralization. In the summer of 2017, I conducted a field survey of invasive and native understory shrubs to see how invasive woody plants influence microbial activity in central New …

Characterization Of Phenolic Acids For Incorporation Into Shape Memory Polymer Foams, Jingyi Liu

Theses - ALL

Shape memory polymer (SMP) foams provide a promising new option for hemorrhage control on the battlefield; however, they lack a mechanism to control wound infections that can delay healing processes. Adding phenolic acids (PAs) into SMP foams provides a natural, non-drug option for incorporations of antioxidant and antimicrobial functionalities that may promote healing. However, PAs lack a systemic characterization of their structure/property relationships, and their chemical incorporation into SMP foams may alter their efficacy. In this work, a library of PAs was screened in terms of antioxidant and antimicrobial properties to provide a full understanding of how their structure affects …

Variation In Herbivore Effects On Grassland Primary Production: A Test Of Three Models, Jacob Penner

Theses - ALL

Grazing animals influence a wide range of plant and soil processes in the world’s grasslands. Ecologists have long understood that grazing can stimulate aboveground net primary production (ANPP), although this phenomenon has not been broadly generalizable across grasslands and grazing regimes. The mechanisms underlying grazer stimulation of ANPP are therefore of interest to a wide variety of stakeholders from ecologists to land managers. Three data-supported hypotheses offer differing explanations for the ways in which grazing interacts with resource availability to drive ANPP: the compensatory continuum hypothesis (CCH) implicates background resource availability, the limiting resource model (LRM) considers the direct effects …

There Must Be Something In The Water: Understanding Pfas Contamination Of Groundwater As A National Security Issue, Kylie N. Ford

Student Theses 2015-Present

This report addresses the widespread pollution of domestic groundwater resources with Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS) caused by firefighting activities performed at military installations across the United States. Two former military bases in Southeastern Pennsylvania are used as a single case study: the Naval Air Development Center (NADC) in Warminster and the Naval Air Station Joint Reserve Base (NASJRB) in Horsham. Chapter 1 gives a history of domestic military bases from the perspective of the infrastructure buildup and downsizing that occurred over the 20th Century, along with the environmental degradation revealed during brownfield redevelopment. The chapter then gives specifics about …

Fighting Food Insecurity For Nyc Children And Youth: Urban Agriculture And Food Justice, Devin C. O'Mara

Student Theses 2015-Present

The positive benefits of urban agriculture go beyond just providing fresh and healthy food to metropolitan areas. As the practice of urban farming has become increasingly more popular over the last decade or so, it has proven to develop community relations and aide with metropolitan and global issues such as poverty. Children and teens especially benefit from urban agriculture, specifically those that comes from underprivileged homes that may not have the resources to obtain fresh food every day. A shocking number of kids can go hungry every day due to lack of available food. Many children that live in metropolitan …

Broadening Footpaths: Trail Ecology And Ethic, Miles H. Frank

Student Theses 2015-Present

There is not always a clear distinction between what constitutes responsible use and what constitutes overuse with regard to recreation and the environment. Even on a small scale, outdoor recreation will always leave a footprint. This paper addresses the ecological impact that the growth of outdoor recreation has had on the environment. Using a multi-disciplinary approach, it provides a holistic analysis of the issue from the scale of local vegetation to that of national policy and wilderness philosophy. Chapter one focuses on the immediate impacts of the overuse of hiking trails and the subsequent environmental degradation of at-risk areas. It …

Preserving The Trauma Narrative Of The Hunger Games: As Based In The Novels, The Films, And Morality, Rio Turnbull

Undergraduate Honors Theses

This thesis discusses both the technical aspects and the moral aspects of preserving trauma when adapting a trauma novel to film, in specific relation to Suzanne Collins’s The Hunger Games. The thesis begins by arguing the Hunger Games story as a trauma narrative in its original form, but not so in its film adaptations, and supports this argument by defining the defining characteristics of the trauma narrative–which is voicelessness and an altered sense of self and society, embedded in the internal experience–and applying it to The Hunger Games trilogy, identifying where these occur in the novels and do not …

Functional Implications Of Nlrp1 Variants For Autoimmune Disease, Laura J. Westhoff

Undergraduate Honors Theses

NLRP1 is a protein-coding human gene that plays a crucial role in the NLRP1 inflammasome. Variants to the NLRP1 gene have been associated with autoimmune and autoinflammatory diseases. We examined the effects of polymorphisms at two SNPs on cytokine levels and NLRP1 gene expression in 50 human volunteers without diagnosed autoimmune disease. NLRP1 was genotyped at SNPs rs2670660 and rs12150220 and individuals who were homozygous at one or more SNP were selected for further analysis. Serum IL-18 and IL-1β levels were quantified using ELISA. NLRP1 gene expression was measured using real-time PCR. A strong linkage was found between genotypes of …

The Effects Of Replacement Of Fish Meal Protein With A Mixture Of Poultry By-Product Meal, Fish Silage And Fish Protein Hydrolysate On The Growth Performances Of Asian Sea Bass (Lates Calcarifer), Yu-Cong Hong, Angela Chien, Shyn-Shin Sheen

Journal of Marine Science and Technology–Taiwan

This feeding trial was conducted to investigate the effects of replacement of dietary fishmeal (FM) with a mixture of poultry by-product meal (PBM), fish silage (FS) and fish protein hydrolysate (FPH) on the growth performances of the Asian sea bass Lates calcarifer. Five isonitrogenous (46% crude protein) and isolipidic (12% crude lipid) diets were formulated to replace 0 (CON), 25 (FM 25), 50 (FM 50), 75 (FM 75) and 100% (FM 100) of fishmeal protein with the protein mixture (78% PBM, 11% FS, and 11% FPH). One additional diet, namely POM was designed to completely replace FM protein with PBM. …

Design And Development Of A Perfusion Bioreactor With Internal Volume Expansion And Cell Retention For Cell And Gene Therapy Manufacturing, Corinna Doris

KGI Theses and Dissertations

Economically producing patient-specific cell therapies at commercial levels remains a challenge as it requires manufacturing separate batches per patient where the production system must be scaled-out rather than scaled-up to supply more patient doses. The resulting high production cost and consequent price-point can limit patient access. Specifically, the current cell expansion processes are highly manual and laborious, with the number and complexity of operations and components increasing the opportunities for failure and contamination. This work therefore aims to design a mechanically simple bioreactor that is better suited for scale-out by consolidating the cell expansion process to fewer components, vessels, and …

Estimating Carbon Flux From Optically Recording Total Particle Volume At Depths Below The Primary Pycnocline, Alexander B. Bochdansky, Robert B. Dunbar, Dennis A. Hansell, Gerhard J. Herndl

OES Faculty Publications

Optical instruments can rapidly determine numbers and characteristics of water column particles with high sensitivity. Here we show the usefulness of optically assessed total particle volume below the main pycnocline to estimate carbon export in two systems: the open subarctic North Atlantic and the Ross Sea, Antarctica. Both regions exhibit seasonally high phytoplankton production and efficient export (i.e., a strong biological pump). Total particle volumes in the mesopelagic (200-300 m) were significantly correlated with those in the overlying surface mixed layer (50-60 m), indicating that most particles at depth reflect export from the surface. This connectivity, however, is modulated by …

Mta3 Represses Cancer Stemness By Targeting The Sox2ot/Sox2 Axis, Liang Du, Lu Wang, Jinfeng Gan, Zhimeng Yao, Wan Lin, Junkuo Li, Yi Guo, Yuping Chen, Fuyou Zhou, Sai-Ching Jim Yeung, Robert P Coppes, Dianzheng Zhang, Hao Zhang

PCOM Scholarly Works

Cancer cell stemness (CCS) plays critical roles in both malignancy maintenance and metastasis, yet the underlying molecular mechanisms are far from complete. Although the importance of SOX2 in cancer development and CCS are well recognized, the role of MTA3 in these processes is unknown. In this study, we used esophageal squamous cell carcinoma (ESCC) as a model system to demonstrate that MTA3 can repress both CCS and metastasis in vitro and in vivo. Mechanistically, by forming a repressive complex with GATA3, MTA3 downregulates SOX2OT, subsequently suppresses the SOX2OT/SOX2 axis, and ultimately represses CCS and metastasis. More importantly, MTA3

Microbial Communities In Human Milk Relate To Measures Of Maternal Weight, Sara N. Lundgren, Juliette C. Madan, Margaret R. Karagas, Hilary G. Morrison, Anne G. Hoen, Brock C. Christensen

Dartmouth Scholarship

The process of breastfeeding exposes infants to bioactive substances including a diversity of bacteria from breast milk as well as maternal skin. Knowledge of the character of and variation in these microbial communities, as well as the factors that influence them, is limited. We aimed to identify profiles of breastfeeding-associated microbial communities and their association with maternal and infant factors. Bilateral milk samples were collected from women in the New Hampshire Birth Cohort Study at approximately 6 weeks postpartum without sterilization of the skin in order to capture the infant-relevant exposure. We sequenced the V4–V5 hypervariable region of the bacterial …

Seed Mix Experiments And Analysis Of Native Seed Supply For The Pollinator Habitat Initiative, Laura Jackson, Justin Meissen

Tallgrass Prairie Publications and Reports

We examined the relationship between seed mix design, native seed supply, and delivery of ecosystem services by the Conservation Reserve Program, using the CP-42 Pollinator Initiative in Iowa from 2015 to 2019 as a test case. Iowa farmers enrolled over 237,000 acres into this program over a short time, an achievement that is noticeable on the Iowan landscape.