Digital Commons Network^™

Editorial: Long Non-Coding Rnas And Immunity., Grace J Kwon, Jorge Henao-Mejia, Adam Williams

Faculty Research 2019

No abstract provided.

Q&A With Dr. Elizabeth Vargis | College Of Engineering, Utah State University

College of Engineering News

Q: What motivated you to pursue a career in biological engineering? What motivates you to stick with it? A: My father is a mechanical engineer and my mother is a microbiologist. I grew up working with my dad on projects around the house (whether they were necessary or not) and learning about weird diseases and new diagnostic tools from my mom. When I started college, I considered becoming a doctor but found myself more interested in working to make healthcare more effective and accessible. I work on those problems now, making better models of the human eye and developing new …

Dr. Stats Will See You Now: How Math Makes 'Super-Small' Clinical Trials Possible, Matt Windsor

Browse All News

No abstract provided.

Accumulation Over Evolutionary Time As A Major Cause Of Biodiversity Hotspots In Conifers, Mekala Sundaram, Michael J. Donoghue, Aljos Farjon, Denis Filer, Sarah Mathews, Walter Jetz, Andrew B. Leslie

Faculty Publications

© 2019 The Author(s) Published by the Royal Society. All rights reserved. Biodiversity hotspots are important for understanding how areas of high species richness form, but disentangling the processes that produce them is difficult. We combine geographical ranges, phylogenetic relationships and trait data for 606 conifer species in order to explore the mechanisms underlying richness hotspot formation. We identify eight richness hotspots that overlap known centres of plant endemism and diversity, and find that conifer richness hotspots occur in mountainous areas within broader regions of long-term climate stability. Conifer hotspots are not unique in their species composition, traits or phylogenetic …

Healing The Encounter Between People And Place In Southern Appalachia, Caroline Merritt

Expressive Therapies Capstone Theses

In southern Appalachia, we fail to make visible the roots. Existing not as a geographical location but as a socially constructed culture and a concentrated source of exploited energy, the region reflects a necessary element of the postcolonial American imagination. For nationally lucrative resources such as coal, oil, lumber, and natural gas to be extracted without consideration or consciousness for the people and the place of its origin, the otherized Appalachian stereotype must prevail. Further crystalizing this false construction, white Appalachian scholars traditionally address current health disparities via the victimization of poor white Appalachia. The capitalist initiative to concentrate power …

Detecting Parasite Associations Within Multi-Species Host And Parasite Communities, Tad A. Dallas, Anna Liisa Laine, Otso Ovaskainen

Faculty Publications

© 2019 The Author(s) Published by the Royal Society. All rights reserved. Understanding the role of biotic interactions in shaping natural communities is a long-standing challenge in ecology. It is particularly pertinent to parasite communities sharing the same host communities and individuals, as the interactions among parasites—both competition and facilitation—may have far-reaching implications for parasite transmission and evolution. Aggregated parasite burdens may suggest that infected host individuals are either more prone to infection, or that infection by a parasite species facilitates another, leading to a positive parasite–parasite interaction. However, parasite species may also compete for host resources, leading to the …

Understanding The Biopsychological Effects Of Trauma On Learning: An Investigation Of Interventions To Support Faculty, Joan Buzick

Seton Hall University Dissertations and Theses (ETDs)

The current era in higher education has brought changes to the academic profession. Faculty have an increasing number of responsibilities in addition to their traditional role as an instructor. At the same time, faculty are engaging with a changing and diverse student population. The population has more challenges, with increased stressors, than have been historically observed in higher education students. For many, the stressors are trauma-related and are a growing concern. Trauma has been shown to impact cognitive, social, emotional, and physical well-being. What has been learned about trauma is, to a great extent, a result of the relatively recently …

The Missouri Miner, October 9, 2019

The Missouri Miner Newspaper

No abstract provided.

Using Traditional Ecological Knowledge To Understand And Adapt To Climate And Biodiversity Change On The Pacific Coast Of North America, V. R. De Echeverria, Thomas F. Thornton

Faculty, Staff, and Students

We investigate the perceptions and impacts of climate change on 11 Indigenous communities in Northern British Columbia and Southeast Alaska. This coastal region constitutes an extremely dynamic and resilient social-ecological system where Indigenous Peoples have been adjusting to changing climate and biodiversity for millennia. The region is a bellwether for biodiversity changes in coastal, forest, and montane environments that link the arctic to more southerly latitudes on the Pacific coast. Ninety-six Elders and resource users were interviewed to record Traditional Ecological Knowledge (TEK) and observations regarding weather, landscape, and resource changes, especially as concerns what we term Cultural Keystone Indicator …

The Impact Of European Private Law Upon The Mixed Legal Systems Of Cyprus, Nicholas Mouttotos

Journal of Civil Law Studies

This article attempts to examine the impact of European private law upon the legal system of Cyprus taking into account its mixed elements and whether these elements have contributed towards a smooth reception of EU law. While Nikitas Hatzimihail argued in 2013 that it may still be too early to assess the impact of European Union (EU) law upon the legal system of Cyprus, the financial crisis and its effects render such an assessment possible. Building upon Hatzimihail’s work in his effort at understanding a “unique” legal system by using comparative law theory to understand the doctrinal development and elaboration …

Comprehensive National Nutrition Survey: Preliminary Factsheets, Ministry Of Health And Family Welfare, Government Of India, Unicef, Population Council

Reproductive Health

No abstract provided.

C. Elegans Synmuv B Proteins Regulate Spatial And Temporal Chromatin Compaction During Development, Meghan Elizabeth Costello, Lisa N. Petrella

Biological Sciences Faculty Research and Publications

Tissue-specific establishment of repressive chromatin through creation of compact chromatin domains during development is necessary to ensure proper gene expression and cell fate. Caenorhabditis elegans synMuv B proteins are important for the soma/germline fate decision and mutants demonstrate ectopic germline gene expression in somatic tissue, especially at high temperature. We show that C. elegans synMuv B proteins regulate developmental chromatin compaction and that the timing of chromatin compaction is temperature sensitive in both wild type and synMuv B mutants. Chromatin compaction in mutants is delayed into developmental time periods when zygotic gene expression is upregulated and demonstrates an anterior-to-posterior pattern. …

Spectator 2019-10-09, Editors Of The Spectator

The Spectator

No abstract provided.

Syntheses, Characterization, And Preliminary Evaluation Of Potential Ruthenium Anticancer Complexes Containing Schiff Base Ligands, Stephen Mensah

Theses and Dissertations

Platinum-based drugs have over the years been administered in the treatment of tumours.

Unfortunately, platinum resistance and the severe side effects associated with the treatments has necessitated the research for new anti-cancer drugs. Ruthenium(II) and Ruthenium(III) complexes have shown promise as useful alternative anticancer agents. The lead candidates include the Ru(II) complex RAPTA-C, a ruthenium(II)-arene complex [Ru(η6-p-cymene)Cl2(1,3,5-triaza-7-phosphaadamantane)] and the Ru(III) complex NAMI-A [imidazoleH][trans-Ru(imidazole) (dimethyl sulfoxide)Cl4]. Both compounds have shown potent cytotoxic activity in several primary human tumor models. Unfortunately, NAMI-A could not advance in clinical evaluations due to limited efficacy in vivo, while the clinical evaluation of RAPTA-C is unknown. …

Comprehensive National Nutrition Survey: 2016–2018, Ministry Of Health And Family Welfare, Government Of India, Unicef, Population Council

Reproductive Health

No abstract provided.

Relating The Gut Metagenome And Metatranscriptome To Immunotherapy Responses In Melanoma Patients., Brandilyn A. Peters, Melissa Wilson, Una Moran, Anna Pavlick, Allison Izsak, Todd Wechter, Jeffrey S. Weber, Iman Osman, Jiyoung Ahn

Department of Medical Oncology Faculty Papers

BACKGROUND: Recent evidence suggests that immunotherapy efficacy in melanoma is modulated by gut microbiota. Few studies have examined this phenomenon in humans, and none have incorporated metatranscriptomics, important for determining expression of metagenomic functions in the microbial community.

METHODS: In melanoma patients undergoing immunotherapy, gut microbiome was characterized in pre-treatment stool using 16S rRNA gene and shotgun metagenome sequencing (n = 27). Transcriptional expression of metagenomic pathways was confirmed with metatranscriptome sequencing in a subset of 17. We examined associations of taxa and metagenomic pathways with progression-free survival (PFS) using 500 × 10-fold cross-validated elastic-net penalized Cox regression.

RESULTS: Higher …

Molecular Phylogeny Implemented In An Introductory Plant Classification Course, Chao Cai, Jo Ann Banks

Libraries Faculty and Staff Presentations

Plant classification is one of the core components in undergraduate programs related to plant sciences. Traditionally plant classification courses primarily introduce morphology-based taxonomy because of practical needs in the field. However, the publication of new plant classification systems by Angiosperm Phylogeny Group (APG) using molecular phylogeny methods leads to the trends of using molecular evidence (DNA barcode) for plant identification. In our introductory plant classification course, we included a two-week module (lectures and labs) to introduce key concepts and fundamental skills in molecular phylogeny. Week 1 included concepts of evolutionary tree thinking, data mining in NCBI using BLAST search, and …

Chitosan Biosynthesis And Virulence In The Human Fungal Pathogen Cryptococcus Gattii, Woei C Lam, Rajendra Upadhya, Charles A Specht, Abigail E Ragsdale, Camaron R Hole, Stuart M Levitz, Jennifer K Lodge

Open Access Publications

No abstract provided.

The Bg News October 09, 2019, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. October 09, 2019. Volume 99-Issue 9.

Use Of Compound Specific Δ13c Stable Isotope Analysis For Intact Triacylglcerides Using High Temperature Gas Chromatography Up To 430°C., P Sutton, M Tuthorn, J Newton

School of Geography, Earth and Environmental Sciences

No abstract provided.

Environmental Controls On Surf Zone Injuries On High-Energy Beaches, Bruno Castelle, Tim Scott, Rob Brander, Jak Mccarroll, Arthur Robinet, Eric Tellier, Korte E De, Bruno Simonnet, Louis Rachid Salmi

School of Biological and Marine Sciences

Abstract. The two primary causes of surf zone injuries (SZIs) worldwide, including fatal drowning and severe spinal injuries, are rip currents (rips) and shore-break waves. SZIs also result from surfing and bodyboarding activity. In this paper we address the primary environmental controls on SZIs along the high-energy meso–macro-tidal surf beach coast of southwestern France. A total of 2523 SZIs recorded by lifeguards over 186 sample days during the summers of 2007, 2009 and 2015 were combined with measured and/or hindcast weather, wave, tide, and beach morphology data. All SZIs occurred disproportionately on warm sunny days with low wind, likely because …

University Honors Program News, Georgia Southern University

Honors College: News & Publications (2008-2020)

• Cross-Cultural Experiences in Cancer Research

A Current Update On Human Papillomavirus-Associated Head And Neck Cancers., Ebenezer Tumban

Michigan Tech Publications, Part 1

Human papillomavirus (HPV) infection is the cause of a growing percentage of head and neck cancers (HNC); primarily, a subset of oral squamous cell carcinoma, oropharyngeal squamous cell carcinoma, and laryngeal squamous cell carcinoma. The majority of HPV-associated head and neck cancers (HPV + HNC) are caused by HPV16; additionally, co-factors such as smoking and immunosuppression contribute to the progression of HPV + HNC by interfering with tumor suppressor miRNA and impairing mediators of the immune system. This review summarizes current studies on HPV + HNC, ranging from potential modes of oral transmission of HPV (sexual, self-inoculation, vertical and horizontal …

Venetoclax: Evidence To Date And Clinical Potential, Luis Miguel Juárez-Salcedo, Viraj Desai, Samir Dalia

Student Publications

The emergence of targeted therapy for patients with hematological diseases has permanently altered the therapeutic landscape. Immunochemotherapy regimes are now more and more being replaced by targeted therapies due to superior efficacy and better safety profiles. However, evolution and selection of subclones with continuous treatment leads to disease relapse and resistance toward these novel drugs. Venetoclax, the highly selective BCL-2 inhibitor (ABT-199), has an acceptable safety profile. To date, it has been approved for the treatment of first-line and relapsed/refractory chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML). However, extension of indications can be expected in monotherapy and in …

Postbreeding Habitat Use By Golden-Cheeked Warblers (Setophaga Chrysoparia), Melanie R. Colón, Mark R. Hutchinson, Ashley M. Long, Gary Voelker, Michael L. Morrison

Western North American Naturalist

The period following breeding but prior to migration is an important, though understudied, component of the avian annual life cycle. We quantified habitat use by endangered Golden-cheeked Warblers (Setophaga chrysoparia) during the postbreeding period in Golden-cheeked Warbler breeding habitat (i.e., oak-juniper [Quercus-Juniperus] woodlands) predominated by Texas oak (Quercus buckleyi) or post oak (Q. stellata), as well as in immediately adjacent oak woodland, oak savanna, and riparian vegetation not usually associated with breeding activity for this species. Most (87%) of the Golden-cheeked Warblers we detected were in oak-juniper woodlands, especially in Texas oak …

Quantification Of Eccentricity In Stems Of Artemisia Tridentata Nutt., Lance S. Evans, Tiffany A. Kharran, Ismael Pena, Stanley G. Kitchen

Western North American Naturalist

Previous research has shown that stems of Artemisia tridentata species exhibit extensive lobe formation. Twenty-two stem samples of Artemisia tridentata Nutt. ssp. wyomingensis (ARTRW) and 24 samples of A. t. ssp. tridentata (ARTRT) were investigated to quantify lobe formation characteristics. For samples of both subspecies, lobe formation values were constant for 8.3-cm-diameter stems. For the above samples, ARTRW had 14 xylem rings, while ARTRT had only 5 rings. Three stem samples (33 to 50 cm long) of ARTRW were cut into a series of 8-mm segments. For the 3 stems, the smallest ends had 8 xylem rings (10 mm^{2 …}

Description Of The Adult Female Of Diplocentrus Lachua (Scorpiones: Scorpionidae: Diplocentrinae) From Northeastern Alta Verapaz, Guatemala, Rony E. Trujillo, Luis F. De Armas, Carlos A. Gaitán

Euscorpius

The female of the scorpion Diplocentrus lachua Armas, Trujillo & Agreda, 2011 is herein described, on the basis of a single specimen collected at Parque Nacional Laguna Lachuá, Alta Verapaz Department, Guatemala, type locality for this species. An emended diagnosis is provided and the known distribution of all described Guatemalan Diplocentrus species is graphically presented.

To Look Or Not To Look: Acknowledging Facial Stigmas In The Interview To Reduce Discrimination, Juan M. Madera, Mikki Hebl

Personnel Assessment and Decisions

As the use of technology-mediated interviews (e.g., Skype) is becoming a standard method to interview applicants, it is important to understand how discrimination can still manifest in these types of interviews. Because technology-mediated interviews focus on applicants’ faces, discrimination based on facial stigmas can be particularly inevitable. Thus, the purpose of the current study is to examine how a facial stigma affects visual attention during a technology-mediated interview and acknowledgment as a remediation strategy that individuals might use to reduce the amount of visual attention on a facial stigma. We used a 2 (acknowledge: yes or no) x 2 (target …

Doe Biological And Environmental Research User Facilities, Louis J. Terminello

National Lab Day

No abstract provided.

Montana Technological University Energy R&D Capabilities, Beverly K. Hartline

National Lab Day

No abstract provided.