Digital Commons Network^™

Regulation Of Lipophagy In Nafld By Cellular Metabolism And Cd36, Dmitri Samovski, Nada A. Abumrad

Open Access Publications

No abstract provided.

Synthesis And Characterization Of Diazirine Alkyne Probes For The Study Of Intracellular Cholesterol Trafficking, Mckenna Feltes, Samantha Moores, Sarah E. Gale, Kathiresan Krishnan, Laurel Mydock-Mcgrane, Douglas F. Covey, Daniel S. Ory, Jean E. Schaffer

Open Access Publications

No abstract provided.

Building Bridges: Pcsk7 As A Nafld Candidate Gene Connecting Hepatic Inflammation With Hypertriglyceridemia, Rotonya M. Carr, Nicholas O. Davidson

Open Access Publications

No abstract provided.

The Complex Genetics And Biology Of Human Temperament: A Review Of Traditional Concepts In Relation To New Molecular Findings, C. Robert Cloninger, Kevin M. Cloninger, Igor Zwir, Lisa Keltikangas-Järvinen

Open Access Publications

No abstract provided.

Oxytocin And Oxytocinase In The Obese And Nonobese Parturients During Induction And Augmentation Of Labor, Annemaria De Tina, Jeremy Juang, Thomas F Mcelrath, Jack D Baty, Arvind Palanisamy

Open Access Publications

No abstract provided.

Regulated Phosphosignaling Associated With Breast Cancer Subtypes And Druggability, Kuan-Lin Huang, Yige Wu, Tina Primeau, Joshua F. Mcmichael, Adam D. Scott, Song Cao, Michael C. Wendl, Kimberly J. Johnson, Jason Held, Sherri Davies, R. Reid Townsend, Feng Chen, David Fenyö, Shunqiang Li, Tao Liu, Li Ding, Et Al.

Open Access Publications

No abstract provided.

Hepatic Monoacylglycerol Acyltransferase 1 Is Induced By Prolonged Food Deprivation To Modulate The Hepatic Fasting Response, Andrew J. Lutkewitte, Kyle S. Mccommis, George G. Schweitzer, Kari T. Chambers, Mark J. Graham, Lingjue Wang, Gary J. Patti, Angela M. Hall, Brian N. Finck

Open Access Publications

No abstract provided.

Synthesis Of Oxidized Phospholipids By Sn-1 Acyltransferase Using 2–15-Hete Lysophospholipids, Gao-Yuan Liu, Sung Ho Moon, Christopher M. Jenkins, Harold F. Sims, Shaoping Guan, Richard W. Gross

Open Access Publications

No abstract provided.

Insulin-Independent Reversal Of Type-1 Diabetes Following Transplantation Of Adult Brown Adipose Tissue Supplemented With Igf-1, Subhadra C. Gunawardana, David W. Piston

Open Access Publications

No abstract provided.

Co-Registered Photoacoustic And Ultrasound Imaging Of Human Colorectal Cancer, Guang Yang, Eghbal Amidi, William C. Chapman Jr., Sreyankar Nandy, Atahar Mostafa, Heba Abdelal, Zahra Alipour, Deyali Chatterjee, Matthew Mutch, Quing Zhu

Open Access Publications

No abstract provided.

High-Density Speckle Contrast Optical Tomography Of Cerebral Blood Flow Response To Functional Stimuli In The Rodent Brain, Tanja Dragojević, Ernesto E. Vidal Rosas, Joseph L. Hollmann, Joseph P. Culver, Carles Justicia, Turgut Durduran

Open Access Publications

No abstract provided.

Graft Immaturity And Safety Concerns In Transplanted Human Kidney Organoids, Sun Ah Nam, Kohei Uchimura, Benjamin D. Humphreys, Et Al.

Open Access Publications

No abstract provided.

Dissemination And Stakeholder Engagement Practices Among Dissemination & Implementation Scientists: Results From An Online Survey, Christopher E. Knoepke, M. Pilar Ingle, Daniel D. Matlock, Ross C. Brownson, Russell E. Glasgow

Open Access Publications

No abstract provided.

Stunting Is Preceded By Intestinal Mucosal Damage And Microbiome Changes And Is Associated With Systemic Inflammation In A Cohort Of Peruvian Infants, Mara Zambruni, Theresa J Ochoa, Anoma Somasunderam, Miguel M Cabada, Maria L Morales, Makedonka Mitreva, Bruce A Rosa, Gonzalo J Acosta, Natalia I Vigo, Maribel Riveros, Sara Arango, David Durand, Maitreyee N Berends, Peter Melby, Netanya S Utay

Open Access Publications

Stunting, defined as height-for-age

Heterogeneity Diffusion Imaging Of Gliomas: Initial Experience And Validation, Qing Wang, Gloria J. Guzmán Pérez-Carrillo, Maria Rosana Ponisio, Pamela Lamontagne, Sonika Dahiya, Daniel S. Marcus, Mikhail Milchenko, Joshua Shimony, Jingxia Liu, Gengsheng Chen, Amber Salter, Parinaz Massoumzadeh, Michelle M. Miller-Thomas, Keith M. Rich, Jonathan Mcconathy, Tammie L. S. Benzinger, Yong Wang

Open Access Publications

OBJECTIVES: Primary brain tumors are composed of tumor cells, neural/glial tissues, edema, and vasculature tissue. Conventional MRI has a limited ability to evaluate heterogeneous tumor pathologies. We developed a novel diffusion MRI-based method-Heterogeneity Diffusion Imaging (HDI)-to simultaneously detect and characterize multiple tumor pathologies and capillary blood perfusion using a single diffusion MRI scan.

METHODS: Seven adult patients with primary brain tumors underwent standard-of-care MRI protocols and HDI protocol before planned surgical resection and/or stereotactic biopsy. Twelve tumor sampling sites were identified using a neuronavigational system and recorded for imaging data quantification. Metrics from both protocols were compared between World Health …

Categorical Encoding Of Decision Variables In Orbitofrontal Cortex, Arno Onken, Jue Xie, Stefano Panzeri, Camillo Padoa-Schioppa

Open Access Publications

No abstract provided.

Glutathione Synthesis Contributes To Virulence Of Streptococcus Agalactiae In A Murine Model Of Sepsis, Elizabeth A Walker, Gary C Port, Michael G Caparon, Blythe E Janowiak

Open Access Publications

No abstract provided.

Congenital Aortic Valve Stenosis, Gautam K Singh

Open Access Publications

Aortic valve stenosis in children is a congenital heart defect that causes fixed form of hemodynamically significant left ventricular outflow tract obstruction with progressive course. Neonates and young infants who have aortic valve stenosis, usually develop congestive heart failure. Children and adolescents who have aortic valve stenosis, are mostly asymptomatic, although they may carry a small but significant risk of sudden death. Transcatheter or surgical intervention is indicated for symptomatic patients or those with moderate to severe left ventricular outflow tract obstruction. Many may need reintervention.

Advanced Glycation End Products Are Elevated In Estrogen Receptor-Positive Breast Cancer Patients, Alter Response To Therapy, And Can Be Targeted By Lifestyle Intervention, Katherine R. Walter, Lindsay L. Peterson, Et Al

Open Access Publications

No abstract provided.

The Children's Respiratory And Environmental Workgroup (Crew) Birth Cohort Consortium: Design, Methods, And Study Population, James E. Gern, Leonard B. Bacharier, Et Al

Open Access Publications

No abstract provided.

Building A Culture Of Health And Well-Being At Merck, Cathryn E. Gunther, Virginia Peddicord, Joseph Kozlowski, Yi Li, Danielle Menture, Raymond Fabius, Sharon Glave Frazee, Peter J. Nigro

Open Access Publications

No abstract provided.

Prevalence And Impact Of Hepatitis E Virus Infection Among Persons With Chronic Hepatitis B Living In The Us And Canada, David R. Mcgivern, Hsing-Hua S. Lin, Junyao Wang, Tiffany Benzine, Henry L.A Janssen, Mandana Khalili, Mauricio Lisker-Melman, Robert J. Fontana, Steven H. Belle, Michael W. Fried

Open Access Publications

No abstract provided.

Washu Epigenome Browser Update 2019, Daofeng Li, Silas Hsu, Deepak Purushotham, Renee L. Sears, Ting Wang

Open Access Publications

No abstract provided.

The Piranha Genome Provides Molecular Insight Associated To Its Unique Feeding Behavior, Manfred Schartl, Susanne Kneitz, Helene Volkoff, Mateus Adolfi, Cornelia Schmidt, Petra Fischer, Patrick Minx, Chad Tomlinson, Axel Meyer, Wesley C. Warren

Open Access Publications

No abstract provided.

Influence Of Diagnostic Method On Outcomes In Phase 3 Clinical Trials Of Bezlotoxumab For The Prevention Of Recurrent Clostridioides Difficile Infection: A Post Hoc Analysis Of Modify I/Ii, Mark H. Wilcox, Galia Rahav, Erik R. Dubberke, Lori Gabryelski, Kerrie Davies, Claire Berry, Karen Eves, Misoo C. Ellison, Dalya Guris, Mary Beth Dorr

Open Access Publications

No abstract provided.

Early Increase Of Csf Strem2 In Alzheimer's Disease Is Associated With Tau Related-Neurodegeneration But Not With Amyloid-Β Pathology, Marc Suarez-Calvet, Yuetiva Deming, Laura Piccio, Celeste M. Karch, Carlos Cruchaga, Et Al

Open Access Publications

No abstract provided.

U.S. Adolescent And Adult Women's Experiences Accessing And Using Toilets In Schools, Workplaces, And Public Spaces: A Multi-Site Focus Group Study To Inform Future Research In Bladder Health, Deepa R Camenga, Sonya S Brady, Cecilia T Hardacker, Beverly R Williams, Jeni Hebert-Beirne, Aimee S James, Kathryn Burgio, Jesse Nodora, Jean F Wyman, Amanda Berry, Lisa K Low, Prevention Of Lower Urinary Tract Symptoms (Plus) Research Consortium

Open Access Publications

The World Health Organization recognizes access to clean and safe toilets as crucial for public health. This study explored U.S. adolescent and adult cisgender women's lived experiences accessing toilets in schools, workplaces, and public spaces. As part of the Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium, we conducted 44 focus groups with female participants (n = 360; ages 11-93). Focus groups were stratified by age (11-14, 15-17, 18-25, 26-44, 45-64, 65+) and conducted across 7 geographically diverse U.S. sites from July 2017-April 2018. Using a transdisciplinary approach, we conducted conventional qualitative coding informed by our PLUS conceptual framework …

Me-Class2 Reveals Context Dependent Regulatory Roles For 5-Hydroxymethylcytosine, Christopher E. Schlosberg, Dennis Y. Wu, Harrison W. Gabel, John R. Edwards

Open Access Publications

No abstract provided.

Aebp1 Down Regulation Induced Cell Death Pathway Depends On Pten Status Of Glioma Cells, Swati Sinha, Arun Renganathan, Prathima B. Nagendra, Vasudeva Bhat, Brian Steve Mathew, Manchanahalli R. Satyanarayana Rao

Open Access Publications

No abstract provided.

Study Of Environmental Enteropathy And Malnutrition (Seem) In Pakistan: Protocols For Biopsy Based Biomarker Discovery And Validation, Najeeha T. Iqbal, Ta-Chiang Liu, Michael J. Barratt, Vanderlene L. Kung, Jeffrey I. Gordon, Et Al

Open Access Publications

No abstract provided.