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Articles 28681 - 28710 of 29568
Full-Text Articles in Entire DC Network
The Macaque Cerebellar Flocculus Outputs A Forward Model Of Eye Movement, Gyutae Kim, Jean Laurens, Tatyana A. Yakusheva, Pablo M. Blazquez
The Macaque Cerebellar Flocculus Outputs A Forward Model Of Eye Movement, Gyutae Kim, Jean Laurens, Tatyana A. Yakusheva, Pablo M. Blazquez
Open Access Publications
No abstract provided.
Psychosocial Moderation Of Polygenic Risk For Cannabis Involvement: The Role Of Trauma Exposure And Frequency Of Religious Service Attendance, Jacquelyn L. Meyers, Emma C. Johnson, Vivia V. Mccutcheon, Kathleen K. Bucholz, Arpana Agrawal, Et Al.
Psychosocial Moderation Of Polygenic Risk For Cannabis Involvement: The Role Of Trauma Exposure And Frequency Of Religious Service Attendance, Jacquelyn L. Meyers, Emma C. Johnson, Vivia V. Mccutcheon, Kathleen K. Bucholz, Arpana Agrawal, Et Al.
Open Access Publications
No abstract provided.
Achieving Tight Control Of A Photoactivatable Cre Recombinase Gene Switch: New Design Strategies And Functional Characterization In Mammalian Cells And Rodent, Kyle Meador, Christina L. Wysoczynski, Aaron J. Norris, Jason Aoto, Michael R. Bruchas, Chandra L. Tucker
Achieving Tight Control Of A Photoactivatable Cre Recombinase Gene Switch: New Design Strategies And Functional Characterization In Mammalian Cells And Rodent, Kyle Meador, Christina L. Wysoczynski, Aaron J. Norris, Jason Aoto, Michael R. Bruchas, Chandra L. Tucker
Open Access Publications
No abstract provided.
Zbtb32 Restrains Antibody Responses To Murine Cytomegalovirus Infections, But Not Other Repetitive Challenges, Arijita Jash, You W. Zhou, Diana K. Gerardo, Tyler J. Ripperger, Bijal A. Parikh, Sytse Piersma, Deepa R. Jamwal, Pawel R. Kiela, Adrianus C. M. Boon, Wayne M. Yokoyama, Chyi S. Hsieh, Deepta Bhattacharya
Zbtb32 Restrains Antibody Responses To Murine Cytomegalovirus Infections, But Not Other Repetitive Challenges, Arijita Jash, You W. Zhou, Diana K. Gerardo, Tyler J. Ripperger, Bijal A. Parikh, Sytse Piersma, Deepa R. Jamwal, Pawel R. Kiela, Adrianus C. M. Boon, Wayne M. Yokoyama, Chyi S. Hsieh, Deepta Bhattacharya
Open Access Publications
No abstract provided.
Blending Insights From Implementation Science And The Social Sciences To Mitigate Inequities In Screening For Hereditary Cancer Syndromes, Laura Senier, Colleen M Mcbride, Alex T Ramsey, Vence L Bonham, David A Chambers
Blending Insights From Implementation Science And The Social Sciences To Mitigate Inequities In Screening For Hereditary Cancer Syndromes, Laura Senier, Colleen M Mcbride, Alex T Ramsey, Vence L Bonham, David A Chambers
Open Access Publications
Genomic screening to identify people at high risk for adult-onset hereditary conditions has potential to improve population health. However, if not equitably accessible, genomics-informed screening programs will exacerbate existing health inequities or give rise to new ones. To realize the disease prevention potential of these screening tools, we need strategies to broaden their reach. We propose a conceptual framework that merges insights from implementation science and sociological research on health inequities. Our framework does three things: first, it broadens the arenas of action beyond those typically addressed in implementation science frameworks; second, it argues for recruiting more diverse partners to …
Association Of Polygenic Liability For Alcohol Dependence And Eeg Connectivity In Adolescence And Young Adulthood, Jacquelyn L. Meyers, Emma C Johnson, Arpana Agrawal, Et Al
Association Of Polygenic Liability For Alcohol Dependence And Eeg Connectivity In Adolescence And Young Adulthood, Jacquelyn L. Meyers, Emma C Johnson, Arpana Agrawal, Et Al
Open Access Publications
Differences in the connectivity of large-scale functional brain networks among individuals with alcohol use disorders (AUD), as well as those at risk for AUD, point to dysfunctional neural communication and related cognitive impairments. In this study, we examined how polygenic risk scores (PRS), derived from a recent GWAS of DSM-IV Alcohol Dependence (AD) conducted by the Psychiatric Genomics Consortium, relate to longitudinal measures of interhemispheric and intrahemispheric EEG connectivity (alpha, theta, and beta frequencies) in adolescent and young adult offspring from the Collaborative Study on the Genetics of Alcoholism (COGA) assessed between ages 12 and 31. Our findings indicate that …
Contribution And Interaction Of Shiga Toxin Genes To Escherichia Coli O157:H7 Virulence, Gillian A M Tarr, Taryn Stokowski, Smriti Shringi, Phillip I Tarr, Stephen B Freedman, Hanna N Oltean, Peter M Rabinowitz, Linda Chui
Contribution And Interaction Of Shiga Toxin Genes To Escherichia Coli O157:H7 Virulence, Gillian A M Tarr, Taryn Stokowski, Smriti Shringi, Phillip I Tarr, Stephen B Freedman, Hanna N Oltean, Peter M Rabinowitz, Linda Chui
Open Access Publications
No abstract provided.
Role Of Apd-Ribosylation In Bone Health And Disease, Chun Wang, Gabriel Mbalaviele
Role Of Apd-Ribosylation In Bone Health And Disease, Chun Wang, Gabriel Mbalaviele
Open Access Publications
The transfer of adenosine diphosphate (ADP)-ribose unit(s) from nicotinamide adenine dinucleotide (NAD
Transdermal Fluorescence Detection Of A Dual Fluorophore System For Noninvasive Point-Of-Care Gastrointestinal Permeability Measurement, Richard B Dorshow, J R Johnson, Martin P Debreczeny, I Rochelle Riley, Jeng-Jong Shieh, Thomas E Rogers, Carla Hall-Moore, Nurmohammad Shaikh, L Colleen Rouggly-Nickless, Phillip I Tarr
Transdermal Fluorescence Detection Of A Dual Fluorophore System For Noninvasive Point-Of-Care Gastrointestinal Permeability Measurement, Richard B Dorshow, J R Johnson, Martin P Debreczeny, I Rochelle Riley, Jeng-Jong Shieh, Thomas E Rogers, Carla Hall-Moore, Nurmohammad Shaikh, L Colleen Rouggly-Nickless, Phillip I Tarr
Open Access Publications
The intestinal mucosal barrier prevents macromolecules and pathogens from entering the circulatory stream. Tight junctions in this barrier are compromised in inflammatory bowel diseases, environmental enteropathy, and enteric dysfunction. Dual sugar absorption tests are a standard method for measuring gastrointestinal integrity, however, these are not clinically amenable. Herein, we report on a dual fluorophore system and fluorescence detection instrumentation for which gastrointestinal permeability is determined in a rat small bowel disease model from the longitudinal measured transdermal fluorescence of each fluorophore. This fluorophore technology enables a specimen-free, noninvasive, point-of-care gastrointestinal permeability measurement which should be translatable to human clinical studies.
Metabolically Healthy Obesity: Facts And Fantasies, Gordon I Smith, Bettina Mittendorfer, Samuel Klein
Metabolically Healthy Obesity: Facts And Fantasies, Gordon I Smith, Bettina Mittendorfer, Samuel Klein
Open Access Publications
Although obesity is typically associated with metabolic dysfunction and cardiometabolic diseases, some people with obesity are protected from many of the adverse metabolic effects of excess body fat and are considered "metabolically healthy." However, there is no universally accepted definition of metabolically healthy obesity (MHO). Most studies define MHO as having either 0, 1, or 2 metabolic syndrome components, whereas many others define MHO using the homeostasis model assessment of insulin resistance (HOMA-IR). Therefore, numerous people reported as having MHO are not metabolically healthy, but simply have fewer metabolic abnormalities than those with metabolically unhealthy obesity (MUO). Nonetheless, a small …
Mechanism Of Microtubule Plus-End Tracking By The Plant-Specific Spr1 Protein And Its Development As A Versatile Plus-End Marker, Rachappa Balkunde, Layla Foroughi, Eric Ewan, Ryan Emenecker, Valeria Cavalli, Ram Dixit
Mechanism Of Microtubule Plus-End Tracking By The Plant-Specific Spr1 Protein And Its Development As A Versatile Plus-End Marker, Rachappa Balkunde, Layla Foroughi, Eric Ewan, Ryan Emenecker, Valeria Cavalli, Ram Dixit
Open Access Publications
No abstract provided.
Structural And Functional Evidence That Lipoprotein Lpqn Supports Cell Envelope Biogenesis In Mycobacterium Tuberculosis, Geoff C. Melly, Haley Stokas, Jennifer L. Dunaj, Fong Fu Hsu, Malligarjunan Rajavel, Chih-Chia Su, Edward W. Yu, Georgiana E. Purdy
Structural And Functional Evidence That Lipoprotein Lpqn Supports Cell Envelope Biogenesis In Mycobacterium Tuberculosis, Geoff C. Melly, Haley Stokas, Jennifer L. Dunaj, Fong Fu Hsu, Malligarjunan Rajavel, Chih-Chia Su, Edward W. Yu, Georgiana E. Purdy
Open Access Publications
No abstract provided.
Myeloid Acat1/Soat1 Ko Attenuates Pro-Inflammatory Responses In Macrophages And Protects Against Atherosclerosis In A Model Of Advanced Lesions, Elaina M. Melton, Haibo Li, Jalen Benson, Paul Sohn, Li-Hao Huang, Bao-Liang Song, Bo-Liang Li, Catherine C.Y. Chang, Ta-Yuan Chang
Myeloid Acat1/Soat1 Ko Attenuates Pro-Inflammatory Responses In Macrophages And Protects Against Atherosclerosis In A Model Of Advanced Lesions, Elaina M. Melton, Haibo Li, Jalen Benson, Paul Sohn, Li-Hao Huang, Bao-Liang Song, Bo-Liang Li, Catherine C.Y. Chang, Ta-Yuan Chang
Open Access Publications
No abstract provided.
Phosphorylation Of The Hcn Channel Auxiliary Subunit Trip8b Is Altered In An Animal Model Of Temporal Lobe Epilepsy And Modulates Channel Function, Kendall M. Foote, Kyle A. Lyman, Ye Han, Ioannis E. Michailidis, Robert J. Heuermann, Danielle Mandikian, James S. Trimmer, Geoffrey T. Swanson, Dane M. Chetkovich
Phosphorylation Of The Hcn Channel Auxiliary Subunit Trip8b Is Altered In An Animal Model Of Temporal Lobe Epilepsy And Modulates Channel Function, Kendall M. Foote, Kyle A. Lyman, Ye Han, Ioannis E. Michailidis, Robert J. Heuermann, Danielle Mandikian, James S. Trimmer, Geoffrey T. Swanson, Dane M. Chetkovich
Open Access Publications
No abstract provided.
Implementation Of The Uterine Fibroids Option Grid Patient Decision Aids Across Five Organizational Settings: A Randomized Stepped-Wedge Study Protocol, Peter Scalia, Mary C. Politi, Tessa Madden, Et Al
Implementation Of The Uterine Fibroids Option Grid Patient Decision Aids Across Five Organizational Settings: A Randomized Stepped-Wedge Study Protocol, Peter Scalia, Mary C. Politi, Tessa Madden, Et Al
Open Access Publications
No abstract provided.
Developmental Pathology Of Congenital Kidney And Urinary Tract Anomalies, Sanjay Jain, Feng Chen
Developmental Pathology Of Congenital Kidney And Urinary Tract Anomalies, Sanjay Jain, Feng Chen
Open Access Publications
No abstract provided.
Card And Rbpa Modify The Kinetics Of Initial Transcription And Slow Promoter Escape Of The Mycobacterium Tuberculosis Rna Polymerase, Drake Jensen, Ana R. Manzano, Christina L. Stallings, Eric A. Galburt
Card And Rbpa Modify The Kinetics Of Initial Transcription And Slow Promoter Escape Of The Mycobacterium Tuberculosis Rna Polymerase, Drake Jensen, Ana R. Manzano, Christina L. Stallings, Eric A. Galburt
Open Access Publications
No abstract provided.
Are The Intrinsically Disordered Linkers Involved In Ssb Binding To Accessory Proteins?, Min Kyung Shinn, Alexander G. Kozlov, Bihn Nguyen, Wlodek M. Bujalowski, Timothy M. Lohman
Are The Intrinsically Disordered Linkers Involved In Ssb Binding To Accessory Proteins?, Min Kyung Shinn, Alexander G. Kozlov, Bihn Nguyen, Wlodek M. Bujalowski, Timothy M. Lohman
Open Access Publications
No abstract provided.
Npy2r Signaling Gates Spontaneous And Mechanical, But Not Thermal, Pain Transmission, Sihan Chen, Xian-Yu Liu, Yingfu Jiao, Zhou-Feng Chen, Weifeng Yu
Npy2r Signaling Gates Spontaneous And Mechanical, But Not Thermal, Pain Transmission, Sihan Chen, Xian-Yu Liu, Yingfu Jiao, Zhou-Feng Chen, Weifeng Yu
Open Access Publications
No abstract provided.
Comparative Genomic Analysis Of Six Glossina Genomes, Vectors Of African Trypanosomes, Geoffrey M. Attardo, Patrick Minx, Chad Tomlinson, Wesley C. Warren, Richard K. Wilson, Et Al
Comparative Genomic Analysis Of Six Glossina Genomes, Vectors Of African Trypanosomes, Geoffrey M. Attardo, Patrick Minx, Chad Tomlinson, Wesley C. Warren, Richard K. Wilson, Et Al
Open Access Publications
No abstract provided.
Multiple Changes Underlie Allelic Divergence Of Cup2 Between Saccharomyces Species, Xueing C. Li, Justin C. Fay
Multiple Changes Underlie Allelic Divergence Of Cup2 Between Saccharomyces Species, Xueing C. Li, Justin C. Fay
Open Access Publications
No abstract provided.
Microglia Drive Apoe-Dependent Neurodegeneration In A Tauopathy Mouse Model, Yang Shi, Melissa Manis, Justin Long, Kairuo Wang, Patrick M. Sullivan, Javier Remolina Serrano, Rosa Hoyle, David M. Holtzman
Microglia Drive Apoe-Dependent Neurodegeneration In A Tauopathy Mouse Model, Yang Shi, Melissa Manis, Justin Long, Kairuo Wang, Patrick M. Sullivan, Javier Remolina Serrano, Rosa Hoyle, David M. Holtzman
Open Access Publications
No abstract provided.
Rory Regulates The Nlrp3 Inflammasome, Cyrielle Billon, Meghan H. Murray, Amer Avdagic, Thomas P. Burris
Rory Regulates The Nlrp3 Inflammasome, Cyrielle Billon, Meghan H. Murray, Amer Avdagic, Thomas P. Burris
Open Access Publications
No abstract provided.
Thiol Isomerase Erp57 Targets And Modulates The Lectin Pathway Of Complement Activation, Oskar Eriksson, Joyce Chiu, Philip J. Hogg, John P. Atkinson, M. Kathryn Liszewski, Robert Flaumenhaft, Bruce Furie
Thiol Isomerase Erp57 Targets And Modulates The Lectin Pathway Of Complement Activation, Oskar Eriksson, Joyce Chiu, Philip J. Hogg, John P. Atkinson, M. Kathryn Liszewski, Robert Flaumenhaft, Bruce Furie
Open Access Publications
No abstract provided.
Photoreceptors In A Mouse Model Of Leigh Syndrome Are Capable Of Normal Light-Evoked Signaling, Sidney M. Gospe Iii, Amanda M. Travis, Alexander V. Kolesnikov, Mikael Klingeborn, Luyu Wang, Vladimir J. Kefalov, Vadim Y. Arshavsky
Photoreceptors In A Mouse Model Of Leigh Syndrome Are Capable Of Normal Light-Evoked Signaling, Sidney M. Gospe Iii, Amanda M. Travis, Alexander V. Kolesnikov, Mikael Klingeborn, Luyu Wang, Vladimir J. Kefalov, Vadim Y. Arshavsky
Open Access Publications
No abstract provided.
Nfat5 Up-Regulates Expression Of The Kidney-Specific Ubiquitin Ligase Gene Rnf183 Under Hypertonic Conditions In Inner-Medullary Collecting Duct Cells, Yujiro Maeoka, Yan Wu, Takumi Okamoto, Soshi Kanemoto, Xiao Peng Guo, Atsushi Saito, Rie Asada, Koji Matsuhisa, Takao Masaki, Kazunori Imaizumi, Masayuki Kaneko
Nfat5 Up-Regulates Expression Of The Kidney-Specific Ubiquitin Ligase Gene Rnf183 Under Hypertonic Conditions In Inner-Medullary Collecting Duct Cells, Yujiro Maeoka, Yan Wu, Takumi Okamoto, Soshi Kanemoto, Xiao Peng Guo, Atsushi Saito, Rie Asada, Koji Matsuhisa, Takao Masaki, Kazunori Imaizumi, Masayuki Kaneko
Open Access Publications
No abstract provided.
Identification And Characterization Of Nanh2 And Nanh3, Enzymes Responsible For Sialidase Activity In The Vaginal Bacterium Gardnerella Vaginalis, Lloyd S. Robinson, Jane Schwebke, Warren G. Lewis, Amanda L. Lewis
Identification And Characterization Of Nanh2 And Nanh3, Enzymes Responsible For Sialidase Activity In The Vaginal Bacterium Gardnerella Vaginalis, Lloyd S. Robinson, Jane Schwebke, Warren G. Lewis, Amanda L. Lewis
Open Access Publications
No abstract provided.
A Stable Tetramer Is Not The Only Oligomeric State That Mitochondrial Single-Stranded Dna Binding Proteins Can Adopt, Saurabh P. Singh, Vandna Kukshal, Roberto Galletto
A Stable Tetramer Is Not The Only Oligomeric State That Mitochondrial Single-Stranded Dna Binding Proteins Can Adopt, Saurabh P. Singh, Vandna Kukshal, Roberto Galletto
Open Access Publications
No abstract provided.
Activation Of Tel1atm Kinase Requires Rad50 Atpase And Long Nucleosome-Free Dna But No Dna Ends, Sarem Hailemariam, Sandeep Kumar, Peter M. Burgers
Activation Of Tel1atm Kinase Requires Rad50 Atpase And Long Nucleosome-Free Dna But No Dna Ends, Sarem Hailemariam, Sandeep Kumar, Peter M. Burgers
Open Access Publications
No abstract provided.
Detection Of Tar Dna-Binding Protein 43 (Tdp-43) Oligomers As Initial Intermediate Species During Aggregate Formation, Rachel L. French, Zachary R. Grese, Himani Aligireddy, Dhruva D. Dhavale, Ashley N. Reeb, Niraja Kedia, Paul T. Kotzbauer, Jan Bieschke, Yuna M. Ayala
Detection Of Tar Dna-Binding Protein 43 (Tdp-43) Oligomers As Initial Intermediate Species During Aggregate Formation, Rachel L. French, Zachary R. Grese, Himani Aligireddy, Dhruva D. Dhavale, Ashley N. Reeb, Niraja Kedia, Paul T. Kotzbauer, Jan Bieschke, Yuna M. Ayala
Open Access Publications
No abstract provided.