Digital Commons Network^™

Synthesis And Antitumor Activities Of 2-(Piperidin-4-Yl)-Thiazole-4-Carboxamides Analogues Of Tubulysins, Xiangfu Peng, Mingsha Shao, Shuchao Ma, Lei Yao

Turkish Journal of Chemistry

}Tubulysins are a family of natural products that exhibit potent antitumor activities, which have attracted much attention from synthetic and medicinal chemists. Previous attempts to aromatize the Tuv part of tubulysin analogues led to a loss in antitumor activity, which suggested that the Ile and Tuv fragments of these analogues were adopting different conformations than the natural products. In this study, a series of 2-(piperidin-4-yl)-thiazole-4-carboxamides have been prepared to investigate whether an intramolecular H-bond between key NH and OH groups is responsible for the conformational control. The antitumor activities of these analogues have been screened using MDA-MB-231-breast, Siha-cervical, MCF7-breast, and …

Electrochemical Oxidation Of Curcuminoids: An Experimental And Computational Investigation, Zeynep Kalaycioğlu, Nurgül Karadaş, Mehmet Emi̇n Çinar, Si̇bel Ayşil Özkan, Duri̇şehvar Özer Ünal, Ayşegül Gölcü, Fatma Bedi̇a Eri̇m

Turkish Journal of Chemistry

Curcuminoids, reported to have important biological properties, such as antioxidant, anti-Alzheimer, and antidiabetic properties, comprise curcumin (CRM; 1,7-bis [4-hydroxy-3-methoxyphenyl]-1,6-heptadiene-3,5-dione) and its derivatives demethoxycurcumin (DMC; (E,6E)-1-(3,4-dimethoxy-cyclohexyl)-7-(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione) and bisdemethoxycurcumin (BDMC; 1,7-bis[4-hydroxyphenyl]-1,6-heptadiene-3,5-dione). Their electrochemical oxidations are thoroughly explored by applying cyclic and differential pulse voltammetric techniques. The dependence of current intensities and potentials on pH, concentration, scan rate, and nature of the buffer was investigated. The outcome is supported by density functional theory computations indicating the transfer of 4-e$^{-}$/H$^{+}$, 6-e$^{-}$/H$^{+}$, and 8-e$^{-}$/H$^{+}$ couples involved in the oxidation mechanisms of CRM, DMC, and BDMC, respectively, leading to the formation of the same oxidized product.

Determination Of N-Acetylcysteine In The Presence Of Ciprofloxacin Or Levofloxacin In Microparticulate Dry Powder Inhalers, Yağmur Akdağ Çayli, Selma Şahi̇n, Emi̇rhan Nemutlu, Levent Öner

Turkish Journal of Chemistry

A fast and easy method was validated for simultaneous determination of ciprofloxacin hydrochloride monohydrate (CP), levofloxacin hemihydrate (LV), and N-acetylcysteine (NAC) in samples. The analysis was performed on a C$_{18}$ column (250 x 4.6 mm, 5 μm) (Inertsil ODS-3V) using an isocratic elution method with a mobile phase composed of 25 mM KH$_{2}$PO$_{4}$ (pH 3.0) and methanol (72:28, v/v) at a flow rate of 1 mL/min. UV detection was performed at 214 nm for NAC and 293 nm for CP and LV. The method was validated for linearity, accuracy, precision (repeatability and reproducibility), specificity, sensitivity, and stability. The calibration study …

Methyl-Substituted 2-Aminothiazole--Based Cobalt(Ii) And Silver(I) Complexes: Synthesis, X-Ray Structures, And Biological Activities, Ezzat Khan, Tufail Ahmad, Zarif Gul, Farhat Ullah, Muhammad Nawaz Tahir, Awal Noor

Turkish Journal of Chemistry

2-Aminothiazole derivatives bear three nucleophilic centers, i.e. endocyclic N, exocyclic NH$_{2}$, and S atom in the ring system. In addition to these centers there are $\pi$-electrons in the ring system which can also expectedly be involved in some sort of coordination. To the best of our knowledge the solid state coordination chemistry of such ligands has not been fully presented in the literature. These ligands (2-amino-4-methylthiazole and 2-amino-5-methylthiazole) were coupled with CoCl$_{2}$ under aerobic conditions to form tetrahedral complexes, bis(2-amino-4-methylthiazole)dichlorocobalt(II) (1) and bis(2-amino-5-methylthiazole)dichlorocobalt(II) (2). Reaction of 2-amino-5-methylthiazole with AgNO$_{3}$ led to an expected two-coordinated, bis(2-amino-5-methylthiazole)silver(I) nitrate (3) as crystalline material. …

Antioxidant Properties Of Water-Soluble Phthalocyanines Containing Quinoline 5-Sulfonic Acid Groups, Armağan Günsel, Esma Hande Alici, Ahmet Turgut Bi̇lgi̇çli̇, Gülnur Arabaci, Meryem Ni̇lüfer Yaraşir

Turkish Journal of Chemistry

In the present study, the antioxidant properties of peripherally and nonperipherally water-soluble tetra (quinoline 5-sulfonic acid) substituted metal-free (1,2), Zn(II) (3, 4), Co(II) (5, 6), and Mn(III)Cl (7, 8) phthalocyanine (Pc) derivatives were reported. In order to determine the antioxidant properties of the Pc compounds, three different commonly known antioxidant methods were used: DPPH ($\alpha $,$\alpha $-diphenyl-$\beta $-picrylhydrazyl) radical scavenging, ferrous ion chelating, and reducing power assays. Compound \textbf{6} showed the best DPPH activity among the other tested compounds except for the standards. The ferrous ion chelating IC$_{50\, }$value of compound 7 was nearly as good as that of the …

Molecular Dynamics Simulations Of Adsorption Of Long Pyrene-Peg Chains On A Thin Carbon Nanotube, Peli̇n Deni̇z Akkuş, Ayşe Özge Kürkçüoğlu Levi̇tas

Turkish Journal of Chemistry

Carbon nanotubes have emerged as highly promising theranostic agents due to their unique structural/physical features, high surface area, and high drug-loading capacity. The high cytotoxicity of carbon nanotubes can be eliminated by noncovalent coating using hydrophilic polymers. We investigated the adsorption of long pyrene functionalized polyethylene glycol (PEG) chains, PEG$_{2000}$ and PEG$_{5000}$, on a single-walled carbon nanotube (SWNT) from a crowded solution. Full-atom molecular dynamics simulations in explicit water were used to mimic the experimental conditions of noncovalent PEGylation with a stoichiometry of one SWNT to ten pyrene-PEG. Although the diffusional behavior of the pyrene molecules still attached to the …

Developing And Modeling Scaffold Free Vascular Constructs, Sanket Pattanaik

MUSC Theses and Dissertations

Despite a strong clinical demand for tissue replacement therapies, few tissue-engineered constructs (TECs) have attained FDA approval. Fewer still demonstrate long term viability of implanted cells, with root causes of failure of these devices identified as poor cell retention, poor vascularization, and inflammation following implantation. Focusing on the first two of these issues, we attempt to create a rapidly vascularizable TEC by optimizing a novel vascular implant model developed in our laboratory: the scaffold-free, prevascular endothelial-fibroblast construct (SPEC). The optimization process calls on a hybrid in vivo, in vitro, and in silico approach. We first developed an in vivo temporal …

Digital Image Processing And Metabolic Parameter Linearity To Noninvasively Detect Analyte Concentration, Joseph Allen Jr

Theses and Dissertations

Spectroscopy is the scientific technique of quantifying and measuring electromagnetic, or light, reflectance or absorption. Atoms emit and/or absorb light when light passes through. The excitations provide specific energy signatures that relate to the element that is emitting or absorbing the light. Non-invasive biosensors monitor physical health properties such as heart rate, oxygen saturation, and tissue blood flow as a result of spectroscopy. Several attempts have been made to non-invasively detect metabolic chemical, or analyte, concentration with various spectroscopic techniques. The primary limitation is due to signal-to-noise ratio. This research focuses on a unique method that combines emission spectroscopy and …

The Mythology Of Sanctuary Cities, Kit Johnson

Faculty Articles

Sanctuary jurisdictions — be they cities, counties, or states — employ various means of disentangling local law enforcement from federal civil immigration enforcement. Much of the criticism directed at these “sanctuary cities” revolves around a set of myths — such as that these jurisdictions are lawless or dangerous. This Essay identifies nine myths about sanctuary cities and subjects each to a fact-based shakedown.

Owning Colors, Deborah Gerhardt, Jon J. Lee

Faculty Articles

Color is powerful. Historically, colors have been invested with mystical, symbolic, and religious significance. We are biologically wired to respond to color cues. A particular color may stimulate emotion, activate memory, and influence perception of the passage of time. Yet the omnipresence of color in our visual world is just the beginning of the story. We have learned to attach many meanings to colors through our lived experiences. Colors have become heuristics for even our abstract ideas. They connect communities. They unite and divide sports fans. They may be shorthand for gender identity, sexual orientation, race, and political identity. Although …

State Benchmark Plan Coverage Of Opioid Use Disorder Treatments And Services: Trends And Limitations, Stacey A. Tovino

Faculty Articles

Professor Tovino offers a survey of state benchmark plan coverage of opioid use disorder treatments and services, and identifies trends and limitations relevant thereto. Part II of the article provides background information regarding opioid use disorder and the treatments and services available for individuals with this disorder. Part III reviews federal mental health parity law and federal mandatory mental health and substance use disorder law as applied to insurance coverage of treatments and services for opioid use disorder, with a focus on the Affordable Care Act's (ACA's) state benchmark health plan selection requirement and the effect on that requirement of …

Method Development And Optimization For The Recovery Of Carbohydrates From A Microalga Species Of Chlorella Vulgaris By Combined Physical And Chemical Pre-Treatments, William Richard Hammann

Theses and Dissertations

A key focus of microalgae-based fuels/chemicals research and development has been on the lipids that many strains generate, but recent studies show that solely recovering these lipids may not be cost competitive with fossil-derived processes. However, if the carbohydrates can also be recovered and ultimately converted into useful chemical intermediates, this may improve the economics for microalgae-based sustainable product technologies.

In the present work, physical and chemical pre-treatments were performed on the Chlorella vulgaris microalgae strain to recover the carbohydrates from the biomass. A central composite design approach was used to optimize hydrolysis conditions including temperature, acid concentration, microalgae solid-to-liquid …

Using Art To Make A Baby: How Rhode Island's Insurance Coverage Mandate Is Preventing Same-Sex Couples From Having Biological Children, Carla Centanni

Roger Williams University Law Review

No abstract provided.

Collegiate Aviation Pilots: Analyses Of Fatigue Related Decision-Making Scenarios, Julius Keller, Flavio Coimbra Mendonca Mr, Jason E. Cutter

International Journal of Aviation, Aeronautics, and Aerospace

According to Dawson and McCulloch (2005), indicating factors for pilot fatigue may be difficult to ascertain. However, fatigue is a probable cause in 15%-20% of all aircraft accidents (Akerstedt, 2000). It may be assumed fatigue has been important latent condition for many of the general aviation incidents and or accidents but not necessarily identified as a probable cause. Events that barely missed a detrimental situation due to fatigue, often go unnoticed and or unreported. Furthermore, fatigue can influence the quality of flight instruction and flight operations overall. The purpose of the current paper was to examine fatigue related decision-making responses …

Determination Of Parameters During Quasi-Steady Stall Maneuver Using Genetic Algorithm, Ambuj Srivastava, Ajit Kumar, Ajoy Kanti Ghosh

International Journal of Aviation, Aeronautics, and Aerospace

The current work offers the determination of longitudinal aerodynamic derivatives during flight manoeuver at angles of attack near the stall. The flight manoeuver near stall is highly non-linear in nature due to separated flow at such elevated angles of attack. Kirchoff’s model for Quasi-Steady Stall Modelling (QSSM) is employed to represent the non-linear nature of aerodynamics during flight manoeuver at elevated angles of attack close to the stall. The Genetic Algorithm (GA) optimized output error method is utilized for estimating the parameters specific to stall characteristics and longitudinal aerodynamics of the ATTAS aircraft. The comparative evaluation of the parameter estimates …

Computation Of Eclipse Time For Low-Earth Orbiting Small Satellites, Sumanth R M

International Journal of Aviation, Aeronautics, and Aerospace

This paper addresses a method for computing eclipse and daylight time for satellites in LEO. Continuous health-monitoring of the satellite is required for the success the mission. For this, the satellites are primarily powered by solar energy but during the eclipse time, the satellite’s functioning is affected as it cannot generate power during this period and also, its temperature drops rapidly. To tackle these issues, computing eclipse time for satellites becomes essential so as to plan for sizing its secondary power source for continuous functioning. In this work, eclipse time is being computed and it is shown that eclipse time …

Fatigue Identification And Management In Flight Training: An Investigation Of Collegiate Aviation Pilots, Flavio A. Coimbra Mendonca Mr, Julius Keller, Chientsung Lu

International Journal of Aviation, Aeronautics, and Aerospace

Objective: The purpose of this study was to evaluate collegiate aviation students’ self-awareness of their fatigue issues; to investigate possible causes of fatigue afflicting collegiate aviation students; and to investigate the collegiate aviation students’ lifestyle and perceptions of personal solutions to fatigue.

Background: Pilot fatigue is a significant safety hazard in aviation operations. Several factors can contribute to fatigue, including inadequate sleep, long work hours, and inadequate nutritional habits. Some factors, such as social and academic activities, could be unique for Title 14 Code of Federal Regulations (CFR) Part 141 collegiate aviation pilots. Previous studies have addressed fatigue in …

[Introduction To] Group Dynamics: Seventh Edition, Donelson R. Forsyth

Bookshelf

Learn how group dynamics theory applies in the real world with the help of this best seller. Group Dynamics, 7th Edition, covers all major theories and topics pertaining to group and team processes. Focus on what's most important with clearly organized chapters and highlighted key points, and see how to apply concepts to actual groups through extended case studies -- one in every chapter. The author draws on examples from a range of disciplines including psychology, management, law, education, sociology, and political science to help you develop a deeper understanding of each topic that you'll take with you …

[Introduction To] Collateral Values: The Natural Capital Created By Landscapes Of War., Todd R. Lookingbill, Peter D. Smallwood

Bookshelf

This book explores the unanticipated benefits that may arise after wars and conflicts, showing how the preservation of battlefields and the establishment of borderlands can create natural capital in the former landscapes of war. The editors call this Collateral Value, in contrast to the collateral damage that war inflicts upon infrastructure, natural capital, and human capital. The book includes case studies recounting successes and failures, opportunities and risks, and ambitious proposals.

The book is organized in two sections. The first visits U.S., English, and French battlefield sites dating from medieval England to World War I. The second explores borderlands located …

Dialogic Teaching In A Detracked High School Ela Class: "We Talk Here", Signy Emler

Theses & Dissertations

This dissertation combines the two fields of dialogic teaching and detracking in a study of one teacher’s English Language Arts high school classroom. The policy of tracking students into separate academic classes perpetuates segregation and is antithetical to the principles of democracy. Dialogic teaching is where students and the teacher engage in inquiry and exploratory talk to co-construct knowledge, and all students are provided with frequent opportunities to express their voices. Grounded in theory that views language and identity as socially constructed and situated, this qualitative case study examined how students from different racial, socio-economic, political and cultural backgrounds worked …

Effects Of Urea And Distillers Inclusion In Finishing Diets On Steer Performance And Carcass Characteristics, Bradley M. Boyd, James C. Macdonald, Matthew K. Luebbe, Galen E. Erickson

Nebraska Beef Cattle Reports

An experiment was conducted to evaluate the effect of supplemental urea in dry rolled corn based finishing diets containing low inclusions of distillers grains. Treatments were set up in a 3 × 3 factorial arrangement. The first factor was wet distillers inclusion at either 10, 15, or 20% of diet DM. The second factor was urea inclusion at either 0, 0.5, or 1.0% of diet dry matter. Increasing inclusion of distillers linearly improved feed conversion and linearly reduced dry matter intake. An interaction for feed efficiency was observed where there was no effect of added urea when 10% or 20% …

Beyond Bird Feed: Proso Millet For Human Health And Environment, Saurav Das, Rituraj Khound, Meenakshi Santra, Dipak K. Santra

Department of Agronomy and Horticulture: Faculty Publications

Domesticated in 8000–10,000 BP in northern China, proso millet (Panicum miliaceum L.) is the best adaptive rotational crop for semiarid central High Plains of the USA, where average annual precipitation is 356–407 mm. Proso millet has multiple benefits when consumed as human food. Proso millet is rich in minerals, dietary fiber, polyphenols, vitamins and proteins. It is gluten-free and therefore, ideal for the gluten intolerant people. Proso millet contains high lecithin which supports the neural health system. It is rich in vitamins (niacin, B-complex vitamins, folic acid), minerals (P, Ca, Zn, Fe) and essential amino acids (methionine and cysteine). …

Winter Wheat Grain Yield Response To Fungicide Application Is Influenced By Cultivar And Rainfall, Emmanuel Byamukama, Shaukat Ali, Jonathan Kleinjan, Dalitso N. Yabwalo, Christopher Graham, Melanie Caffe-Treml, Nathan D. Mueller, John Rickertsen, William A. Berzonsky

Department of Agronomy and Horticulture: Faculty Publications

Winter wheat is susceptible to several fungal pathogens throughout the growing season and foliar fungicide application is one of the strategies used in the management of fungal diseases in winter wheat. However, for fungicides to be profitable, weather conditions conducive to fungal disease development should be present. To determine if winter wheat yield response to fungicide application at the flowering growth stage (Feekes 10.5.1) was related to the growing season precipitation, grain yield from fungicide treated plots was compared to non-treated plots for 19 to 30 hard red winter wheat cultivars planted at 8 site years from 2011 through 2015. …

A Two-Amino Acid Difference In The Coat Protein Of Satellite Panicum Mosaic Virus Isolates Is Responsible For Differential Synergistic Interactions With Panicum Mosaic Virus, R. V. Chowda-Reddy, Nathan A. Palmer, Serge Edme, Gautam Sarath, Frank A. Kovacs, Gary Y. Yuen, Robert Mitchell, Satyanarayana Tatineni

Department of Agronomy and Horticulture: Faculty Publications

Panicum mosaic virus (PMV) (genus Panicovirus, family Tombusviridae) and its molecular parasite, Satellite panicum mosaic virus (SPMV), synergistically interact in coinfected proso and pearl millet (Panicum miliaceum L.) plants resulting in a severe symptom phenotype. In this study, we examined synergistic interactions between the isolates of PMV and SPMV by using PMV-NE, PMV85, SPMV-KS, and SPMV-Type as interacting partner viruses in different combinations. Coinfection of proso millet plants by PMV-NE and SPMV-KS elicited severe mosaic, chlorosis, stunting, and eventual plant death compared with moderate mosaic, chlorotic streaks, and stunting by PMV85 and SPMV-Type. In reciprocal combinations, coinfection …

Soil Fauna Accelerate Dung Pat Decomposition And Nutrient Cycling Into Grassland Soil, Kenneth S. Evans, Martha Mamo, Ana Wingeyer, Walter Schacht, Kent Eskridge, Jeff Bradshaw, Daniel Ginting

Department of Agronomy and Horticulture: Faculty Publications

Soil fauna play critical roles in various ecosystem functions and services, but empirical data measuring their impact on dung pat decomposition and subsequent nutrient cycling into rangeland soils are limited. The objective of this study was to quantify the effect of soil fauna, using dung beetle as an indicator, on dung decomposition and subsequent translocation of dung nutrients into grassland soil over time. A field experiment was conducted early in the summer season and late in the summer season of 2014 and 2015. In each season, dung beetle abundance, changes in dung properties, and subsequent translocation of dung nutrients into …

A Spatial Framework For Ex-Ante Impact Assessment Of Agricultural Technologies, José F. Andrade, Juan I. Rattalino Edreira, Andrew Farrow, Marloes P. Van Loon, Peter Q. Craufurd, Jairos Rurinda, Shamie Zingore, Jordan Chamberlin, Lieven Claessens, Julius Adewopo, Martin K. Van Ittersum, Kenneth G. Cassman, Patricio Grassini

Department of Agronomy and Horticulture: Faculty Publications

Traditional agricultural research and extension relies on replicated field experiments, on-farm trials, and demonstration plots to evaluate and adapt agronomic technologies that aim to increase productivity, reduce risk, and protect the environment for a given biophysical and socio-economic context. To date, these efforts lack a generic and robust spatial framework for ex-ante assessment that: (i) provides strategic insight to guide decisions about the number and location of testing sites, (ii) define the target domain for scaling-out a given technology or technology package, and (iii) estimate potential impact from widespread adoption of the technology(ies) being evaluated. In this study, we developed …

Nebraska’S Natural Resource District System: Collaborative Approaches To Adaptive Groundwater Quality Governance, Gregory N. Sixt, Laurens Klerkx, J. David Aiken, Timothy S. Griffin

Department of Agricultural Economics: Faculty Publications

Nonpoint source pollution of groundwater by nitrates from agricultural activity is a persistent problem for which developing effective policy approaches has proven difficult. There is little empirical information on forms of governance or regime attributes that effectively and sustainably address agricultural nonpoint source pollution of groundwater. Nebraska’s Natural Resource District (NRD) system is a rare example of a groundwater governance regime that is putting programmes in place that are likely to generate sustainable groundwater quality outcomes. We focus on three groundwater nitrate management programmes in the state that collectively represent the broader NRD system. The research shows that four elements …

Ultrastructural Studies Of Acrosomal Formation In The Testis Of Male Greater Cane Rat (Thryonomys Swinderianus), A. O. Adebayo, A. K. Akinloye, Amadi O. Ihunwo, V. O. Taiwo, B. O. Oke

Brain and Mind Institute

Purpose:

In furthering the understanding of the process of spermatogenesis in the greater cane rat, this study describes the ultrastructural spermiogenic transformation and acrosomal formation in the testes of this hystricomorphic rodent that is currently undergoing domestication in parts of West Africa.

Materials and Methods:

Testicular samples were obtained from ten sexually mature cane rats that were perfused-fixed using Karnovsky's fixative (phosphate buffered 2% paraformaldehyde – 2.5% glutaraldehyde fixative at pH 7.4). The samples were processed for ultrastructural analysis and examined under the transmission electron microscope.

Results:

The testes of the cane rat showed uniqueness in its cellular associations and …

Changes On Movement Control Of Dart Throwing Under Distance And Target Weight Constraints, Carlos E. Campos, Guilherme M. Lage, Andre G.P. Andrade, Crislaine R. Couto, Suziane P. Santos, Vitor L.S. Profeta, Herbert Ugrinowitsch

Athletic Performance Research

The aim of the study was to verify the effects of dart weight and target distance on kinematic variables of the movement control of the underarm dart throwing task. Four women and one man performed the task of throwing a dart at two horizontal circular targets located at 2m (Nt) and 3m (Ft) away, with two different weights, 22g (Ld) and 44g (Hd). On the first phase of the experiment, the human volunteers performed 200 trials per day during four sessions. On the fifth day, it had 40 more trials in a pseudo random order that were recorded and analysed. …

การสื่อสารยุคดิจิทัลกับพฤติกรรมการดูแลสุขภาพของพนักงานการท่าเรือแห่งประเทศไทย เขตคลองเตย จังหวัดกรุงเทพมหานคร, วริษฐา จีนโต

Chulalongkorn University Theses and Dissertations (Chula ETD)

การวิจัยเรื่อง “การสื่อสารยุคดิจิทัลกับพฤติกรรมการดูแลสุขภาพของพนักงานการท่าเรือแห่ง ประเทศไทย เขตคลองเตย จังหวัดกรุงเทพมหานคร” มีวัตถุประสงค์เพื่อศึกษาพฤติกรรมการดูแลสุขภาพกับการใช้สื่อสังคมออนไลน์ด้านสุขภาพของพนักงานการท่าเรือแห่งประเทศไทย และศึกษาปัจจัยการใช้สื่อสังคมด้านสุขภาพที่มีความสัมพันธ์กับพฤติกรรมการดูแลสุขภาพของพนักงานการท่าเรือแห่งประเทศไทย เขตคลองเตย จังหวัดกรุงเทพมหานคร ที่ใช้การวิจัยแบบผสมผสาน(Mixed Method) คือ วิจัยเชิงปริมาณและวิจัยเชิงคุณภาพ โดยการสำรวจด้วยแบบสอบถามออนไลน์ จำนวน 100 ชุด สถิติที่ใช้ประกอบด้วยสถิติเชิงบรรยาย (Descriptive statistics) ได้แก่ สถิติค่าความถี่(Frequency) ค่าร้อยละ(Percent) ค่าเฉลี่ย(Mean) และค่าเบี่ยงเบนมาตรฐาน(Standard deviation) สถิติเชิงอนุมาน (Inferential statistics) ได้แก่ การทดสอบค่าเฉลี่ยของกลุ่มตัวอย่างสองกลุ่มที่มีความเป็นอิสระต่อกัน(Independent Sample T-test) การวิเคราะห์ความแปรปรวนทางเดียว(One way ANOVA) การวิเคราะห์ค่าสัมประสิทธิ์สหสัมพันธ์แบบเพียรสัน(Pearson’s Correlation) และการวิเคราะห์ค่าสัมประสิทธิ์สหสัมพันธ์แบบสเปียแมน(Spearman’s Correlation) ผลการเก็บข้อมูลจากการสำรวจจากกลุ่มตัวอย่าง จำนวน 100 คน พบว่า พนักงานการท่าเรือแห่ง ประเทศไทยส่วนใหญ่เป็นเพศหญิง ช่วงอายุ 30-39 ปี มีการศึกษาในระดับปริญญาตรี ส่วนใหญ่มีรายได้ต่อเดือนตั้งแต่ 20,001-30,000 บาท และผู้ตอบแบบสอบถามส่วนใหญ่ไม่มีโรคประจำตัว คิดเป็นร้อยละ 78 ผู้ตอบแบบสอบถามส่วนใหญ่ใช้สื่อสังคมออนไลน์เพื่อรับข้อมูลข่าวสารด้านสุขภาพผ่านสื่อเฟซบุ๊ก(Facebook) คิดเป็นร้อยละ 86 ส่วนการรับข้อมูลด้านสุขภาพผ่านสื่อออนไลน์ของหน่วยงานการท่าเรือฯ ส่วนใหญ่รับสื่อผ่านช่องทางไลน์(Line) จากหน่วยงานสำนักแพทย์และอนามัยการท่าเรือแห่งประเทศไทย ได้รับประโยชน์ด้านความรู้เบื้องต้นในการดูแลสุขภาพและสังเกตความผิดปกติของตนเอง ผู้ตอบแบบสอบถามส่วนใหญ่มีระดับพฤติกรรมการดูแลสุขภาพด้านการป้องกันโรคอยู่ในระดับสูง ผลการวิจัยพบว่า ปัจจัยส่วนบุคคลด้านเพศ อายุและรายได้มีความสัมพันธ์ทางบวกกับพฤติกรรมการดูแลสุขภาพด้านการป้องกันโรคอย่างมีนัยสำคัญทางสถิติที่ระดับ .05 ทัศนคติการรับข่าวสารด้านสุขภาพผ่านสื่อออนไลน์มีความสัมพันธ์ทางบวกกับพฤติกรรมการดูแลสุขภาพด้าน การจัดการความเครียดอย่างมีนัยสำคัญทางสถิติที่ระดับ .05 และความถี่ของสื่อสุขภาพออนไลน์ของหน่วยงาน การท่าเรือฯที่กระตุ้นให้มีการดูแลสุขภาพมากขึ้นมีความสัมพันธ์ทางบวกกับพฤติกรรมการดูแลสุขภาพด้านการจัดการความเครียดและการป้องกันโรคอย่างมีนัยสำคัญทางสถิติที่ระดับ .05