Digital Commons Network^™

In Search Of Solidarity: The Politics Of Queer Activism In New York City, Nathan Shearn

Renée Crown University Honors Thesis Projects - All

No abstract provided.

Historical Ecology And Longitudinal Research Strategies Around Lake Mývatn Iceland, Thomas Mcgovern, George Hambrecht, Megan Hicks

Publications and Research

Historical Ecology has proven to be a very influential tool kit for thinking about complex human interactions with changing landscapes, climate, and other humans. It has also provided concrete and practical frameworks for carrying out sustained long- term place-based research projects that break through traditional periodization to look at the dialectical interaction of human economies and local and regional ecosystems through time. The “longitudinal perspective” pioneered by Carole Crumley’s work in Burgundy has proved to be a very effective tool for carrying out sustained multi-year, multi-investigator, and multi- generational investigations in landscapes around the globe. This paper presents an overview …

Placebo Marks, Jake Linford

Scholarly Publications

Scholars often complain that sellers use trademarks to manipulate consumer perception. This manipulation ostensibly harms consumers by limiting their ability to make informed choices. For example, holding other things constant, consumers spend more money on goods with a high-performance reputation. Critics characterize that result as wasteful, if not anticompetitive. But recent marketing research shows that trademarks with a high-performance reputation may sometimes influence perception to the benefit of the consumer.

A trademark with a high-performance reputation can deliver a performance-enhancing placebo effect. Research subjects perform better at physical and mental tasks when they prepare or play with a product bearing …

Preliminary Study On The Effects Of Akkermensia Muciniphilia On Akt Phosphorylation In Diabetic Pig Models, Brian Ko

Honors Theses

The onset of type 2 diabetes has been shown to affect the Akt signaling pathway, responsible for modulating cellular metabolism. The pro biotic Akkermensia muciniphilia has been recently shown to have an anti-inflammatory, anti-diabetic effect on animals inoculated with it, particularly within the Akt signaling pathway. This preliminary study utilized a twofactor experimental design with streptozotocin-induced diabetes and the presence of Akkermensia muciniphila in pig models in order to elucidate the probiotic's mechanism of action on the disease. Following analysis of insulin-sensitive tissues of muscle, pancreas, and liver, there was observed a mixed response to the presence of the probiotic …

About A Revolution: Toward Integrated Treatment In Drug And Mental Health Courts, Sara Gordon

North Carolina Law Review

No abstract provided.

Hemp On The Horizon: The 2018 Farm Bill And The Future Of Cbd*, Shannon Smith

North Carolina Law Review

No abstract provided.

The Religious Exemption Loophole: A Building Public Health Crisis In North Carolina, Brian Champion

North Carolina Law Review

No abstract provided.

Cultivating A Pedagogy Of Empathy: Teaching Science Fiction In A Changing Biotechnological World, Kathy L. Avery

College of Graduate Studies: Theses & Dissertations

CULTIVATING A PEDAGOGY OF EMPATHY: Teaching Science Fiction in a Changing Biotechnological World

By

KATHY L. AVERY

(Under the Direction of John Weaver)

Abstract

I argue that science fiction affords us the ability to think past our anthropocentrism, opening up a space for us to consider our relationship to burgeoning biotechnologies and the other. I provide critical interpretations of science fiction film and literature, which I believe stimulate the power of the narrative imagination to envision the “netherworld experience of the other”. I believe science fiction provides a site of speculation, a means to better understand and consider the role …

Chasing Nutrients And Algal Blooms In Gulf And Caribbean Waters: A Personal Story, Brian E. Lapointe

Gulf and Caribbean Research

Over the past 5 decades, coastal waters have experienced unprecedented global change, including widespread eutrophication, harmful algal blooms (HAB), dead zones, and loss of biodiversity. During this period, I have studied the effects of nutrients (N, P) on HAB dynamics in tropical seagrass and coral reef ecosystems. Important findings that emerged from my research include: 1) a primary role of anthropogenic nitrogen (N) relative to phosphorus (P) as a driving factor in algal blooms and coastal eutrophication; 2) altered N:P stoichiometry that results in greater P—limitation and metabolic stress in reef corals; 3) recognition that macroalgal blooms be considered as …

Raptor Review, Georgia Southern University

Center for Wildlife Education

• Coming Soon: Wetland Preserve Waterfowl Pond
• Federal Duck Stamps
• 52nd Annual Rattlesnake & Wildlife Festival
• Georgia DNR Recreational Lands: Magnolia Springs State Park in Millen, GA
• Berry College Eagle Cam

Association Of Phlebotomus Guggisbergi With Leishmania Major And Leishmania Tropica In A Complex Transmission Setting For Cutaneous Leishmaniasis In Gilgil, Nakuru County, Kenya, Barrack O. Owino, Damaris Matoke-Muhia, Yasser Alraey, Jackline Milkah Mwangi, Johnstone M. Ingonga, Philip M. Ngumbi, Aitor Casas-Sanchez, Alvaro Acosta-Serrano, Daniel K. Masiga

All Peer-Reviewed Publications

Background Phlebotomus (Larroussius) guggisbergi is among the confirmed vectors for cutaneous leishmaniasis (CL) transmission in Kenya. This scarring and stigmatizing form of leishmaniasis accounts for over one million annual cases worldwide. Most recent CL epidemics in Kenya have been reported in Gilgil, Nakuru County, where the disease has become a public health issue. However, little is known about the factors that drive its transmission. Here, we sought to determine the occurrence, distribution and host blood feeding preference of the vectors, and to identify Leishmania species and infection rates in sandflies using molecular techniques. This information could lead to a better …

Mine Reclamation's Reliance On King Coal: Meeting Legacy Environmental Obligations With A Declining Industry, Claire Jarrell

University of Colorado Law Review

Coal mines throughout Appalachia have left the land scarred and the water damaged. Although mine reclamation programs are the only major system of recourse for addressing environmental degradation caused by mining, the downturn of the coal market has put reclamation programs in a precarious position for achieving that end. Funds for coal mine reclamation are derived from the current coal industry's profits. As coal profits continue to atrophy, so too does the pot of money designated for reclamation efforts. These dwindling financial resources are particularly problematic because there is still significant need for reclamation funding throughout Appalachia.

This Comment explores …

The Quasi-Parent Conundrum, Michael J. Higdon

University of Colorado Law Review

Although family law is very much concerned with legal parentage and its attendant rights, children are much more concerned with maintaining relationships with those who care for them, regardless of whether that person is a legal parent or someone functioning as one. What happens though if the child's legal parent attempts to banish the quasi-parent from the child's life? Doing so can be extremely damaging to the child. Nonetheless, parents do possess a constitutional right to make decisions about how to rear their children, including who may have access to the child.

Trying to strike a balance between protecting the …

Patterns Of Diatom Diversity Correlate With Dissolved Trace Metal Concentrations And Longitudinal Position In The Notheast Pacific Coastal Offshore Transition Zone, P. Dreux Chappell, E. Virginia Armbrust, Katherine A. Barbeau, Randelle M. Bundy, Jagruti Vedamati, Bethany D. Jenkins

OES Faculty Publications

Diatoms are important primary producers in the northeast Pacific Ocean, with their productivity closely linked to pulses of trace elements in the western high nitrate, low chlorophyll (HNLC) region of the oceanographic time series transect 'Line P.' Recently, the coastal-HNLC transition zone of the Line P transect was identified as a hotspot of phytoplankton productivity, potentially controlled by a combination of trace element and macronutrient concentrations. Here we describe diatom community composition in the eastern Line P transect, including the coastal- HNLC transition zone, with a method using high-throughput sequencing of diatom 18S gene amplicons. We identified significant correlations between …

High Rates Of N² Fixation In Temperate, Western North Atlantic Coastal Waters Expands The Realm Of Marine Diazotrophy, Margaret R. Mulholland, P. W. Bernhardt, Brittany Widner, C. R. Selden, P. D. Chappell, S. Clayton, A. Mannino, K. Hyde

OES Faculty Publications

Dinitrogen (N₂) fixation can alleviate N limitation of primary productivity by introducing fixed nitrogen (N) to the world's oceans. Although measurements of pelagic marine N₂ fixation are predominantly from oligotrophic oceanic regions, where N limitation is thought to favor growth of diazotrophic microbes, here we report high rates of N₂ fixation from seven cruises spanning four seasons in temperate, western North Atlantic coastal waters along the North American continental shelf between Cape Hatteras and Nova Scotia, an area representing 6.4% of the North Atlantic continental shelf area. Integrating average areal rates of N₂ fixation during …

Recommended Priorities For Research On Ecological Impacts Of Ocean And Coastal Acidification In The U.S. Mid-Atlantic, Grace K. Saba, Kaitlin A. Goldsmith, Sarah R. Cooley, Daniel Grosse, Shannon L. Meseck, A. Whitman Miller, Beth Phelan, Matthew Poach, Robert Rheault, Kari St. Laurent, Jeremy M. Testa, Judith S. Weis, Richard Zimmerman

OES Faculty Publications

The estuaries and continental shelf system of the United States Mid-Atlantic are subject to ocean acidification driven by atmospheric CO₂, and coastal acidification caused by nearshore and land-sea interactions that include biological, chemical, and physical processes. These processes include freshwater and nutrient input from rivers and groundwater; tidally-driven outwelling of nutrients, inorganic carbon, alkalinity; high productivity and respiration; and hypoxia. Hence, these complex dynamic systems exhibit substantial daily, seasonal, and interannual variability that is not well captured by current acidification research on Mid-Atlantic organisms and ecosystems. We present recommendations for research priorities that target better understanding of the …

Global Perspectives On Observing Ocean Boundary Current Systems, Robert E. Todd, Francisco P. Chavez, Sophie Clayton, Sophie Cravatte, Marlos Goes, Michelle Graco, Xiaopei Lin, Janet Sprintall, Nathalie V. Zilberman, Matthew Archer, Javier Arístegui, Magdalena Balmaseda, John M. Bane, Molly O. Baringer, John A. Barth, Lisa M. Beal, Peter Brandt, Paulo H.R. Calil, Edmo Campos, Luca R. Centurioni, Maria Paz Chidichimo, Mauro Cirano, Meghan F. Cronin, Enrique N. Curchitser, Russ E. Davis, Marcus Dengler, Brad Deyoung, Shenfu Dong, Ruben Escribano, Andrea J. Fassbender, Sarah E. Fawcett, Ming Feng, Gustavo J. Goni, Alison R. Gray, Dimitri Gutiérrez, Dave Hebert, Rebecca Hummels, Shin-Ichi Ito, Marjorlaine Krug, François Lacan, Lucas Laurindo, Alban Lazar, Craig M. Lee, Matthieu Lengaigne, Naomi M. Levine, John Middleton, Ivonne Montes, Mike Muglia, Takeyoshi Nagai, Hilary I. Palevsky, Jaine B. Palter, Helen E. Phillips, Alberto Piola, Albert J. Plueddemann, Bo Qiu, Regina R. Rodrigues, Moninya Roughan, Daniel L. Rudnick, Ryan R. Rykaczewski, Martin Saraceno, Harvey Seim, Alex Sen Gupta, Lynne Shannon, Bernadette M. Sloyan, Adrienne J. Sutton, Luanne Thompson, Anja K. Van Der Plas, Denis Volkov, John Wilkin, Dongxiao Zhang, Linlin Zhang

OES Faculty Publications

Ocean boundary current systems are key components of the climate system, are home to highly productive ecosystems, and have numerous societal impacts. Establishment of a global network of boundary current observing systems is a critical part of ongoing development of the Global Ocean Observing System. The characteristics of boundary current systems are reviewed, focusing on scientific and societal motivations for sustained observing. Techniques currently used to observe boundary current systems are reviewed, followed by a census of the current state of boundary current observing systems globally. Next steps in the development of boundary current observing systems are considered, leading to …

Metaproteomics Reveal That Rapid Perturbations In Organic Matter Prioritize Functional Restructuring Over Taxonomy In Western Arctic Ocean Microbiomes, Molly P. Mikan, H. Rodger Harvey, Emma Timmins-Schiffman, Michael Riffle, Damon H. May, Ian Salter, William S. Noble, Brook L. Nunn

OES Faculty Publications

We examined metaproteome profiles from two Arctic microbiomes during 10-day shipboard incubations to directly track early functional and taxonomic responses to a simulated algal bloom and an oligotrophic control. Using a novel peptide-based enrichment analysis, significant changes (p-value < 0.01) in biological and molecular functions associated with carbon and nitrogen recycling were observed. Within the first day under both organic matter conditions, Bering Strait surface microbiomes increased protein synthesis, carbohydrate degradation, and cellular redox processes while decreasing C1 metabolism. Taxonomic assignments revealed that the core microbiome collectively responded to algal substrates by assimilating carbon before select taxa utilize and metabolize nitrogen intracellularly. Incubations of Chukchi Sea bottom water microbiomes showed similar, but delayed functional responses to identical treatments. Although 24 functional terms were shared between experimental treatments, the timing, and degree of the remaining responses were highly variable, showing that organic matter perturbation directs community functionality prior to alterations to the taxonomic distribution at the microbiome class level. The dynamic responses of these two oceanic microbial communities have important implications for timing and magnitude of responses to organic perturbations within the Arctic Ocean and how community-level functions may forecast biogeochemical gradients in oceans.

Seasonal Variability Of Forces Controlling Sedimentation In The Sundarbans National Forest, Bangladesh, Rip P. Hale, C. A. Wilson, E. J. Bomer

OES Faculty Publications

Southwest Bangladesh, located on the Ganges-Brahmaputra-Meghna delta, is experiencing the impacts of sea level rise (SLR) due to processes at both the local and global scale. In particular, regional alterations of the hydrodynamic network, due to embankment construction, have drastically altered effective SLR, placing millions of inhabitants at risk of prolonged inundation, and threatening the world’s largest continuous mangrove stand, the Sundarbans National Forest (SNF). In order to effectively employ landscape recovery solutions, an understanding of local sediment transport and deposition is critical. This field-based study investigates the sediment dynamics between the mangrove platform and tidal channels of the SNF …

Ebullition Of Oxygen From Seagrasses Under Supersaturated Conditions, Matthew H. Long, Kevin Sutherland, Scott D. Wankel, David J. Burdige, Richard C. Zimmerman

OES Faculty Publications

Gas ebullition from aquatic systems to the atmosphere represents a potentially important fraction of primary production that goes unquantified by measurements of dissolved gas concentrations. Although gas ebullition from photosynthetic surfaces has often been observed, it is rarely quantified. The resulting underestimation of photosynthetic activity may significantly bias the determination of ecosystem trophic status and estimated rates of biogeochemical cycling from in situ measures of dissolved oxygen. Here, we quantified gas ebullition rates in Zostera marina meadows in Virginia, U.S.A. using simple funnel traps and analyzed the oxygen concentration and isotopic composition of the captured gas. Maximum hourly rates of …

Spatial Structuring And Life History Connectivity Of Antarctic Silverfish Along The Southern Continental Shelf Of The Weddell Sea, Jilda Alicia Caccavo, Julian R. Ashford, Svenja Ryan, Chiara Papetti, Michael Schröder, Lorenzo Zane

OES Faculty Publications

A multi-disciplinary approach was employed to examine a physical-biological population hypothesis for a critical forage species, the Antarctic silverfish Pleuragramma antarctica. Caccavo et al. (2018; Sci Rep 8:17856) had shown strong gene flow along the westward Antarctic Slope Current, in addition to spatially recurring length modes that provided evidence for episodic connectivity. In this paper, otolith nucleus chemistry from a subset of fish collected in the southern Weddell Sea as part of a hydrographic survey of the Filchner Trough system was used to test between connectivity scenarios. Nucleus chemistry, which reflects environmental exposure during early life, showed significant …

Dinitrogen Fixation Across Physico-Chemical Gradients Of The Eastern Tropical North Pacific Oxygen Deficient Zone, C. R. Selden, M. R. Mulholland, P.W. Bernhardt, B. Widner, A. Macías-Tapia, Q. Ji, A. Jayakumar

OES Faculty Publications

The Eastern Tropical North Pacific Ocean hosts one of the world's largest oceanic oxygen deficient zones (ODZs). Hot spots for reactive nitrogen (N_r) removal processes, ODZs generate conditions proposed to promote N_r inputs via dinitrogen (N₂) fixation. In this study, we quantified N₂ fixation rates by ¹⁵N tracer bioassay across oxygen, nutrient, and light gradients within and adjacent to the ODZ. Within subeuphotic oxygen‐deplete waters, N₂ fixation was largely undetectable; however, addition of dissolved organic carbon stimulated N₂ fixation in suboxic (μmol/kg O₂) waters, suggesting that diazotroph communities are …

Bomb Radiocarbon Age Validation For The Long-Lived, Unexploited Arctic Fish Species Coregonus Clupeaformis, John M. Casselman, Cynthia M. Jones, Steven E. Campana

OES Faculty Publications

The growth rates of freshwater fish in the Arctic would be expected to be very low, but some previous studies of lake whitefish (Coregonus clupeaformis) have reported relatively rapid growth and longevity estimates of less than 15 years. We used bomb radiocarbon chronologies to validate an ageing method based on otolith sections for lake whitefish in both an unexploited Arctic lake (MacAlpine Lake; longevity 50 years) and a lightly exploited temperate population (Lake Simcoe; longevity 49 years). Our results confirm previous suggestions that other ageing methods can seriously underestimate lake whitefish age after ~5–8 years. A Chapman–Robson estimate …

A Full-Ocean-Depth Rated Modular Lander And Pressure-Retaining Sampler Capable Of Collecting Hadal-Endemic Microbes Under In Situ Conditions, Logan M. Peoples, Matthew Norenberg, David Price, Madeline Mcgoldrick, Mark Novotny, Alexander Bochdansky, Douglas H. Bartlett

OES Faculty Publications

The hadal zone remains one of the least studied environments because of its inaccessibility, in part because of hydrostatic pressures extending to 110 MPa. Few instruments are capable of sampling from such great depths. We have developed a full-ocean-depth-capable lander that can be fit with sampling packages for the collection of still images, video, motile megafauna, and hadal seawater. One payload includes a pressure-retaining sampler (PRS) able to maintain seawater samples under in situ pressure during recovery. We describe the technical specifications of the lander and the PRS and preliminary results from three deployments at depths in excess of 10,700 …

Vertical Sleeve Gastrectomy Improves Ventilatory Drive Through A Leptin-Dependent Mechanism, Deanna M. Arble, Alan R. Schwartz, Vsevolod Y. Polotsky, Darleen A. Sandoval, Randy J. Seeley

Biological Sciences Faculty Research and Publications

Obesity hypoventilation syndrome (OHS) is a serious disorder characterized by daytime hypercapnia, disordered breathing, and a reduction in chemosensitivity. Vertical sleeve gastrectomy (VSG), a bariatric surgical procedure resulting in weight loss and weight-independent improvements in glucose metabolism, has been observed to substantially improve sleep-disordered breathing. However, it is unclear if the ventilatory effects of VSG are secondary to weight loss or the marked change in metabolic physiology. Using preclinical mouse models, we found that VSG leads to an improvement in the hypercapnic ventilatory response (HCVR) and reductions in circulating leptin levels independent of reductions in body mass, fat mass, and …

Safety In Children With Medical Complexity: Our Canaries In The Coal Mine?, Christine A. Schindler, Elisabeth S. Pordes, Steven D. Finkenbinder, K. Jane Lee

College of Nursing Faculty Research and Publications

Purpose of review

The goal of this paper is to describe the complicated and diverse safety risks facing children with medical complexity.

Recent findings

Children with medical complexity have an increased risk of experiencing adverse health outcomes related to multiple comorbidities, the complicated nature of their care, and frequent interactions with the health care system. The safety risks experienced by children with medical complexity are in large part due to the complex nature of their care rather than the specific risks posed by the complicated nature of their illnesses.

Summary

The complicated nature of care for children with medical complexity …

Pharmaceutical Drugs Of Uncertain Value, Lifecycle Regulation At The Us Food And Drug Administration, And Institutional Incumbency, Matthew Herder

Articles, Book Chapters, & Popular Press

Policy Points

• The US Food and Drug Administration (FDA) has in recent years allowed onto the market several drugs with limited evidence of safety and effectiveness, provided that manufacturers agree to carry out additional studies while the drugs are in clinical use.
• Studies suggest that these postmarketing requirements (PMRs) frequently lack transparency, are subject to delays, and fail to answer the questions of greatest clinical importance. Yet, none of the literature speaks directly to the challenges that the FDA—as a regulatory institution—encounters in enforcing PMRs.
• Through a series of interviews with FDA leadership, this article analyzes and situates those challenges …

Accounting For Intermediaries And Transnational Linkages In The Multi-Level Perspective: Mongolia’S Renewable Energy Transition, Madeline Lee

CMC Senior Theses

As the international community takes increasing action to mitigate the effects of climate change, increased focus has been placed on the topic of energy transitions in developing countries. This paper uses the multi-level perspective (MLP) framework to analyze the ongoing energy transition in Mongolia, specifically the integration of large-scale wind and solar energy systems. Attention is paid to the presence of transnational linkages and intermediaries that have substantially contributed to Mongolia’s success in diffusing renewable energy technology, as well as challenges Mongolia has faced as a result of limited technological and institutional capacity. The paper concludes that Mongolia’s transition shares …

Global Consciousness: A Functionalist Neurophilosophical Perspective, Connor C. Bowen

CMC Senior Theses

The purpose of this thesis is to explore a thought-provoking consequence of the functionalist theory of mind. Given the current organizational structure of Earth and field theories of consciousness in neuroscience, Earth is probably conscious. The argument is explored through an examination of the current organizational structure of Earth and field theories of consciousness in neuroscience, which leads to the conclusion that Earth is conscious. Various theories of mind have been proposed by neuroscientists and philosophers alike in an attempt to qualify what consciousness is and what provides the basis for consciousness to occur. Support, in the form of data …

The Characterization Of Alzheimer’S Disease And The Development Of Early Detection Paradigms: Insights From Nosology, Biomarkers And Machine Learning, Isabel Milano

CMC Senior Theses

Alzheimer’s Disease (AD) is the only condition in the top ten leading causes of death for which we do not have an effective treatment that prevents, slows, or stops its progression. Our ability to design useful interventions relies on (a) increasing our understanding of the pathological process of AD and (b) improving our ability for its early detection. These goals are impeded by our current reliance on the clinical symptoms of AD for its diagnosis. This characterizations of AD often falsely assumes a unified, underlying AD-specific pathology for similar presentations of dementia that leads to inconsistent diagnoses. It also hinges …