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2019

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Susceptibility Of Borrelia Burgdorferi Morphological Forms To Chemical Antimicrobials, Ann-Aubrey Kaiwilani Reid Nov 2019

Susceptibility Of Borrelia Burgdorferi Morphological Forms To Chemical Antimicrobials, Ann-Aubrey Kaiwilani Reid

Theses and Dissertations

Borrelia burgdorferi is the etiological agent of Lyme disease. Not much is known about the susceptibility of this organism to chemical disinfection. Current antimicrobial susceptibility test methods, such as those published by the American Society for Testing and Materials (ASTM), usually require assessment of the number of colony forming units (cfu) of growing organisms on plates following exposure to an agent. For fast-growing organisms, plates are ready for counting 1-2 days post plating, while several weeks may be needed for slower growing organisms. Spirochetes, like B. burgdorferi are difficult to grow on solid media and typically require long incubation periods, …

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Investigation Of Thymidine Kinase 1 In Cancer Progression, Eliza Esther King Bitter Nov 2019

Investigation Of Thymidine Kinase 1 In Cancer Progression, Eliza Esther King Bitter

Theses and Dissertations

Understanding cancer biomarkers for diagnosis and prognosis leads to improved patient treatments and care. This thesis addresses the relevance of thymidine kinase 1 (TK1) as a cancer biomarker and the role of TK1 in cancer progression. Worldwide, cancer leads to more than 12 million deaths annually. In the United States alone, each year over 1.5 million cases will be diagnosed and over half a million persons will die. The most prevalent cancer types include skin, lung, breast, prostate, and colon. TK1 is known to be present in the serum of patients with multiple cancer types, including lung, breast, colon and …

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A Study Of Preservation Aspects Of Libraries In Srinagar, Dr. Mohammad Ishaq Lone, Abdul Wahid, Abdul Shakoor Nov 2019

A Study Of Preservation Aspects Of Libraries In Srinagar, Dr. Mohammad Ishaq Lone, Abdul Wahid, Abdul Shakoor

Library Philosophy and Practice (e-journal)

Although libraries are in existence from the time writing got evolved. However, preservation aspects were not taken into consideration seriously till recent times when the damage by different factors was noticed. The damage by insects, human, environmental factors and others could cause a vacuum to the already accumulated knowledge over the centuries of human history. The present study is an effort in this direction to ascertain the various facts related to preservation in different libraries in Srinagar, the summer capital of Jammu & Kashmir. The situation can be considered to be threatening as there is lack of awareness among the …

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Developing A Transfection Method For Didymium Iridis, Uriel Adolfo Baray Nov 2019

Developing A Transfection Method For Didymium Iridis, Uriel Adolfo Baray

College of Science and Health Theses and Dissertations

The plasmodial slime mold and member of Mycetozoa, Didymium iridis, has been studied in a variety of contexts such as RNA editing (Traphagen et al., 2010; Hendrickson and Silliker, 2010a; Hendrickson and Silliker, 2010b), mitochondrial inheritance (Silliker et al., 2002), biological speciation (Betterley and Collins, 1983; Clark et al., 1991) and mating competency (Shipley and Holt, 1982). Further studies are hindered by the lack of a transfection protocol, which would allow for gene manipulation in D. iridis (hereafter Didymium). Transfection methods developed in the related slime molds, Physarum polycephalum (Burland et al., 1993) and Dictyostelium discoideum (Fey et al., 1995; …

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Songbird Use Of Problem-Solving Feeders In Urban And Rural Areas, Kayce Miller Nov 2019

Songbird Use Of Problem-Solving Feeders In Urban And Rural Areas, Kayce Miller

College of Science and Health Theses and Dissertations

Behavioral flexibility is important for animals to adapt to novel situations in their environment. It has been suggested that birds living in complex environments (e.g., urban areas) should be more flexible than conspecifics in less complex environments. Birds are a particularly well studied group, where novel foraging problems are used to assess flexibility and problem-solving performance of urban and rural animals of the same species; however, this is most frequently done in a lab setting with wild-caught birds originating from different habitats. Using a field-based method to test problem-solving performance should give additional insight into other factors influencing birds’ flexibility. …

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Entry By Multiple Picornaviruses Is Dependent On A Pathway That Includes Tnk2, Wasl, And Nck1, Hongbing Jiang, Christian Leung, Stephen Tahan, David Wang Nov 2019

Entry By Multiple Picornaviruses Is Dependent On A Pathway That Includes Tnk2, Wasl, And Nck1, Hongbing Jiang, Christian Leung, Stephen Tahan, David Wang

Open Access Publications

Comprehensive knowledge of the host factors required for picornavirus infection would facilitate antiviral development. Here we demonstrate roles for three human genes,

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Evaluating Climate Change Impacts On Drinking Water Reservoirs And Wastewater System Resilience In Connecticut, U.S.A., Cristina Mullin Nov 2019

Evaluating Climate Change Impacts On Drinking Water Reservoirs And Wastewater System Resilience In Connecticut, U.S.A., Cristina Mullin

Doctoral Dissertations

Societies depend on the proper functioning and resilience of critical infrastructure systems including those for drinking water and wastewater, but these systems are vulnerable to natural and anthropogenic stressors. For example, wastewater systems are especially susceptible to extreme weather events while drinking water systems are vulnerable to diminished source water quality — both of which can disrupt proper functioning. Climate change and human development, economic problems, and pollution further challenge water system resilience. Despite the criticality of these systems and known vulnerabilities, little scholarship exists that aims to interrogate their resilience. This dissertation attempts to narrow this gap in the …

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Immune-Mediated Colitis From Dual Checkpoint Inhibitors., Nishanth Thalambedu, Yasir Khan, Qian Zhang, Shristi Khanal, Ammar Ashfaq Nov 2019

Immune-Mediated Colitis From Dual Checkpoint Inhibitors., Nishanth Thalambedu, Yasir Khan, Qian Zhang, Shristi Khanal, Ammar Ashfaq

Abington Jefferson Health Papers

Melanoma is a deadly disease with immunotherapy treatment options that emerged in the last few years and have changed the disease outcome. However, it is associated with immune-related toxic effects despite improving survival. We present the case of a 53-year-old woman who had two weeks of diarrhea after she was treated with dual immunotherapy agents for her advanced melanoma. The final workup revealed pancolitis, possibly due to immunotherapy adverse effects. Initial conservative treatment, unfortunately, did not lead to a clinical improvement until a steroid was introduced. We are reporting this case to alert our fellow physicians about the immune-mediated toxicities …

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New Insights Into The Lactate Shuttle: Role Of Mct4 In The Modulation Of The Exercise Capacity., Sara Bisetto, Megan C Wright, Romana A Nowak, Angelo C Lepore, Tejvir S Khurana, Emanuele Loro, Nancy J Philp Nov 2019

New Insights Into The Lactate Shuttle: Role Of Mct4 In The Modulation Of The Exercise Capacity., Sara Bisetto, Megan C Wright, Romana A Nowak, Angelo C Lepore, Tejvir S Khurana, Emanuele Loro, Nancy J Philp

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Lactate produced by muscle during high-intensity activity is an important end product of glycolysis that supports whole body metabolism. The lactate shuttle model suggested that lactate produced by glycolytic muscle fibers is utilized by oxidative fibers. MCT4 is a proton coupled monocarboxylate transporter preferentially expressed in glycolytic muscle fibers and facilitates the lactate efflux. Here we investigated the exercise capacity of mice with disrupted lactate shuttle due to global deletion of MCT4 (MCT4−/−) or muscle-specific deletion of the accessory protein Basigin (iMSBsg−/−). Although MCT4−/− and iMSBsg−/− mice have normal muscle morphology and contractility, only MCT4−/− mice exhibit an exercise intolerant …

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Dengue Hemorrhagic Fever: A Scientometric Study, Janarthanan Pichai, . Prabakar Stanleay Dr., . Nithyanandam Kannan Dr. Nov 2019

Dengue Hemorrhagic Fever: A Scientometric Study, Janarthanan Pichai, . Prabakar Stanleay Dr., . Nithyanandam Kannan Dr.

Library Philosophy and Practice (e-journal)

“Dengue Hemorrhagic Fever” is the topic selected for the Scientometric study to assess the responsibilities of the global scientists through the measurement of the impact of their research publications. “Dengue Hemorrhagic Fever” affects the health of the society and particularly the young generation are suffering a lot and many of them destined to “Early Death”. The Scientometric study in this research reveals that only 646 publications were published from 2009 to 2018, which means the research contribution on “Dengue Hemorrhagic Fever” is very low. The country wise publications show that “India” leads the table with more number of publications than …

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Trissopathes (Anthozoa: Antipatharia) In The North-East Atlantic, With A Description Of T. Grasshoffi Sp. Nov., Tina N. Molodtsova, Álvaro Altuna, Jason M. Hall-Spencer Nov 2019

Trissopathes (Anthozoa: Antipatharia) In The North-East Atlantic, With A Description Of T. Grasshoffi Sp. Nov., Tina N. Molodtsova, Álvaro Altuna, Jason M. Hall-Spencer

School of Biological and Marine Sciences

A new species of antipatharian (black coral) in the genus Trissopathes is described. It is common in the bathyal zone of the north-east Atlantic, including the Bay of Biscay, Celtic Slope and adjacent banks and seamounts. The species is often observed in underwater photographs from untrawled parts of carbonate mounds in the area. Trissopathes grasshoffi sp. nov. can be easily distinguished from its three congeners by having relatively sparse branching, a higher density of primary pinnules, and 3–6 secondary anterolateral pinnules as well as by the shape and size of its spines. The present state of knowledge of Trissopathes is …

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Distinct Vip And Pacap Functions In The Distal Nerve Stump During Peripheral Nerve Regeneration, Xin Peng Dun Nov 2019

Distinct Vip And Pacap Functions In The Distal Nerve Stump During Peripheral Nerve Regeneration, Xin Peng Dun

More Faculty of Health Research

No abstract provided.

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Using Paleosols To Reconstruct Past Environments Before, During And After Periods Of Anatomically Human Migration At Gona, Ethiopia, Kevin Takashita-Bynum Nov 2019

Using Paleosols To Reconstruct Past Environments Before, During And After Periods Of Anatomically Human Migration At Gona, Ethiopia, Kevin Takashita-Bynum

Steeplechase: An ORCA Student Journal

Environmental change is thought to have driven dispersals of Anatomically Modern Humans (AMH) out of Africa, yet the precise landscape context of these migrations remains unclear. Furthermore, river-based archives of paleoenvironment during periods of dispersal are scarce. Gona, an area in northeastern Ethiopia with one of the most continuous records of East African Paleolithic and Neolithic archaeology, contains abundant Middle to Late Pleistocene river deposits interbedded with volcanic ash. This study examines the physical and chemical changes of 11 fossilized soils (paleosols) extracted from Gona’s paleoanthropological sites that range in age from the Middle to the Late Pleistocene (~380-11 ka). …

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Keep The Faith Not The Guilt: Demonization Of Sex Workers, Jessica Hodges Nov 2019

Keep The Faith Not The Guilt: Demonization Of Sex Workers, Jessica Hodges

Steeplechase: An ORCA Student Journal

Previous research shows that religiosity and attitudes about sexual topics are strongly correlated and typically negative. That is, as religiosity increases, views toward sexual topics tend to become more conservative or generally more negative in valence. However, current research also suggests that one’s sexual guilt may be the mediating influence in the relationship between religiosity and negative sexual attitudes. The present study seeks to replicate and extend research that examined the extent to which an individual's religiosity and sexual guilt influence their perspective of pornography and sex workers (Study 1). To replicate this (Study 2), a survey containing relevant measures …

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J. Michael Queen (1948 – 2019): A Memorial, Arthur N. Palmer Nov 2019

J. Michael Queen (1948 – 2019): A Memorial, Arthur N. Palmer

International Journal of Speleology

No abstract provided.

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Drivers Of Ant Composition, Richness, And Trophic Guilds In Neotropical Iron Ore Cavities, Rodrigo A. Castro-Souza, Thais G. Pellegrini, Marconi Souza-Silva, Rodrigo L. Ferreira Nov 2019

Drivers Of Ant Composition, Richness, And Trophic Guilds In Neotropical Iron Ore Cavities, Rodrigo A. Castro-Souza, Thais G. Pellegrini, Marconi Souza-Silva, Rodrigo L. Ferreira

International Journal of Speleology

Subterranean habitats may be considered limiting for animal colonization, especially for ants, due to permanent darkness and mainly because of oligotrophic conditions. While not as deep as limestone caves, iron ore caves and other subterranean habitats may be more available for colonization because of their shallower depth. We use the richness and composition of ants to assess how differences in habitat structure affect the biodiversity and ecosystem function between cavities and surrounding epigean landscapes. We predicted that the distribution of ants would be different because of the variation in habitat structure and cavity conditions may act as a filter for …

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Rawls, Climate Change, And Essential Goods, Gloria Li Nov 2019

Rawls, Climate Change, And Essential Goods, Gloria Li

Acta Cogitata: An Undergraduate Journal in Philosophy

Climate change is one of the most important social and environmental justice issues of the 21st century. As such, it deserves serious treatment by John Rawls, perhaps the most important social justice theorist of the 20th century. In this paper, I first discuss Rawls’ conception of a well-ordered society presented in A Theory of Justice and how climate change may be incorporated in his principles of justice as an intergenerational savings problem. Then, I present a characterization of environmental goods like clean air and clean water as a special kind of good in Rawlsian justice and argue that this is …

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Acta Cogitata - Volume 7, C. Áine Keefer, W. John Koolage Nov 2019

Acta Cogitata - Volume 7, C. Áine Keefer, W. John Koolage

Acta Cogitata: An Undergraduate Journal in Philosophy

No abstract provided.

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Tools To Support Collaboration In Educating Emergent Multilingual Students: Jumpstart And Electronic Performance Log, Margaret Bouchard, W. Jason Stegemoller Nov 2019

Tools To Support Collaboration In Educating Emergent Multilingual Students: Jumpstart And Electronic Performance Log, Margaret Bouchard, W. Jason Stegemoller

i.e.: inquiry in education

Collaboration is a vital component of educating emergent multilingual students, and technology plays an integral role in supporting the process. This article presents two tools to facilitate collaboration among emergent multilingual students: Jumpstart and Electronic Performance Log. The authors developed the digital tools in concert with paraeducators and teachers during a two-year, grant-funded, professional development program. In their roles as participant-observers, the authors were able to work with paraeducators and teachers to create tools that fit within the learning context during a professional development program for high school paraeducators. Concepts from activity theory are used to demonstrate that teaching emergent …

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Effectiveness Of Cooperative Learning On Students Achievement In Genetics, Self-Efficacy And Conceptions Of Learning Biology, Demet Arı, Özlem Sadi Nov 2019

Effectiveness Of Cooperative Learning On Students Achievement In Genetics, Self-Efficacy And Conceptions Of Learning Biology, Demet Arı, Özlem Sadi

i.e.: inquiry in education

The purpose of this study is to analyze the effect of cooperative learning, which is defined as the process of working in small groups to achieve a goal, on students’ general academic achievement in “General Principles of Genetics” unit, their academic self-efficacy and conceptions of learning biology (COLB). In the study, in order to investigate the effects of cooperative learning and the teaching method that the biology curriculum in Turkey anticipates on the students’ academic achievement, their self-efficacy and COLB, pre-test/post-test control group quasi experimental design was used. The study was administered to 126 Turkish high school students from four …

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Inquiry In Education: Crossing The Borders, Antonina Lukenchuk Nov 2019

Inquiry In Education: Crossing The Borders, Antonina Lukenchuk

i.e.: inquiry in education

No abstract provided.

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The Ticker, November 25, 2019 Nov 2019

The Ticker, November 25, 2019

The Ticker

The Ticker is the student newspaper of Baruch College. It has been published continuously since 1932, when the Baruch College campus was the School of Business and Civic Administration of the City College of New York.

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Pancreatic Islets Communicate With The Brain Via Vagal Sensory Neurons, Madina Makhmutova Nov 2019

Pancreatic Islets Communicate With The Brain Via Vagal Sensory Neurons, Madina Makhmutova

Open Access Dissertations

Sensory denervation affects pancreatic islet function, glucose metabolism and diabetes onset, but how islet endocrine cells interact with sensory neurons has not been studied. In this thesis work we attempted to anatomically and physiologically characterize vagal islet-brain pathway in search of the sensory modality that islet is transmitting to the brain. Here we show that the pancreatic islets are innervated by vagal sensory axons expressing substance P, calcitonin-gene related peptide, and serotonin receptor 5HT3R. Vagal neurons projecting to the pancreas terminate in the commissural nucleus of the solitary tract. These neurons respond to chemical but not mechanical stimulation of the …

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11-25-2019 Zebrafish Research Pioneer To Speak At Swosu About Neurological Development, Southwestern Oklahoma State University Nov 2019

11-25-2019 Zebrafish Research Pioneer To Speak At Swosu About Neurological Development, Southwestern Oklahoma State University

THE BARK ARCHIVE 2019

Dr. Judith Eisen, professor of biology at the University of Oregon, will be guest speaker at the Southwestern Oklahoma State University Department of Biological Sciences J.D. Maness Seminar Series on Wednesday, December 4.

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Johnson Research Show Bats In Attics Good For Conservation, Ohio University College Of Arts & Sciences Nov 2019

Johnson Research Show Bats In Attics Good For Conservation, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

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Mia-Sig: Multiplex Chromatin Interaction Analysis By Signal Processing And Statistical Algorithms., Minji Kim, Meizhen Zheng, Simon Zhongyuan Tian, Byoungkoo Lee, Jeffrey Chuang, Yijun Ruan Nov 2019

Mia-Sig: Multiplex Chromatin Interaction Analysis By Signal Processing And Statistical Algorithms., Minji Kim, Meizhen Zheng, Simon Zhongyuan Tian, Byoungkoo Lee, Jeffrey Chuang, Yijun Ruan

Faculty Research 2019

The single-molecule multiplex chromatin interaction data are generated by emerging 3D genome mapping technologies such as GAM, SPRITE, and ChIA-Drop. These datasets provide insights into high-dimensional chromatin organization, yet introduce new computational challenges. Thus, we developed MIA-Sig, an algorithmic solution based on signal processing and information theory. We demonstrate its ability to de-noise the multiplex data, assess the statistical significance of chromatin complexes, and identify topological domains and frequent inter-domain contacts. On chromatin immunoprecipitation (ChIP)-enriched data, MIA-Sig can clearly distinguish the protein-associated interactions from the non-specific topological domains. Together, MIA-Sig represents a novel algorithmic framework for multiplex chromatin interaction analysis.

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Building Capacity For Collaborative Research On Opioid And Other Substance Use Disorders Through The Clinical And Translational Science Award Program, Linda B. Cottler, Alan I. Green, Harold Alan Pincus, Scott Mcintosh, Jennifer L. Humensky, Kathleen Brady Nov 2019

Building Capacity For Collaborative Research On Opioid And Other Substance Use Disorders Through The Clinical And Translational Science Award Program, Linda B. Cottler, Alan I. Green, Harold Alan Pincus, Scott Mcintosh, Jennifer L. Humensky, Kathleen Brady

Project ECHO Bibliography

The opioid crisis in the USA requires immediate action through clinical and translational research. Already built network infrastructure through funding by the National Institute on Drug Abuse (NIDA) and National Center for Advancing Translational Sciences (NCATS) provides a major advantage to implement opioid-focused research which together could address this crisis. NIDA supports training grants and clinical trial networks; NCATS funds the Clinical and Translational Science Award (CTSA) Program with over 50 NCATS academic research hubs for regional clinical and translational research. Together, there is unique capacity for clinical research, bioinformatics, data science, community engagement, regulatory science, institutional partnerships, training and …

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What's Happening: November 25, 2019, Maine Medical Center Nov 2019

What's Happening: November 25, 2019, Maine Medical Center

What's Happening

No abstract provided.

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Pediatric Brainstem Gliomas: An Institutional Experience, Altaf Ali Laghari, Mirza Zain Baig, Muhammad Ehsan Bari, Aneela Darbar, Naureen Mushtaq, Umme E Hani Abdullah, Daniya Aziz Khan Nov 2019

Pediatric Brainstem Gliomas: An Institutional Experience, Altaf Ali Laghari, Mirza Zain Baig, Muhammad Ehsan Bari, Aneela Darbar, Naureen Mushtaq, Umme E Hani Abdullah, Daniya Aziz Khan

Section of Neurosurgery

Objective: The aim of this study was to analyze the clinical profiles and outcomes of pediatric brainstem gliomas treated at our institute.
Methodology: We reviewed the files of 18 pediatric age group patients diagnosed with brainstem glioma at our institution. The following variables were recorded: age, sex, duration of symptoms, date of diagnosis, main clinical symptoms, Karnofsky performance status score, magnetic resonance imaging findings, histopathology findings, details of the treatment given, disease progression, and date of mortality/last follow-up. This data were then transferred to SPSS version 23 which was used for further analysis.
Results: The mean age of our cohort …

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Mapping Seafloor Relative Reflectance And Assessing Coral Reef Morphology With Eaarl-B Topobathymetric Lidar Waveforms, Nicholas Wilson, Christopher E. Parrish, Tim Battista, C. Wayne Wright, Bryan Costa, Richard K. Slocum, Jennifer A. Dijkstra, Matthew T. Tyler Nov 2019

Mapping Seafloor Relative Reflectance And Assessing Coral Reef Morphology With Eaarl-B Topobathymetric Lidar Waveforms, Nicholas Wilson, Christopher E. Parrish, Tim Battista, C. Wayne Wright, Bryan Costa, Richard K. Slocum, Jennifer A. Dijkstra, Matthew T. Tyler

Center for Coastal and Ocean Mapping

Topobathymetric lidar is becoming an increasingly valuable tool for benthic habitat mapping, enabling safe, efficient data acquisition over coral reefs and other fragile ecosystems. In 2014, a novel topobathymetric lidar system, the Experimental Advanced Airborne Research Lidar-B (EAARL-B), was used to acquire data in priority habitat areas in the U.S. Virgin Islands (USVI), spanning the 0–44-m depth range. In this study, new algorithms and procedures were developed for generating seafloor relative reflectance, along with a suite of shape-based waveform features from EAARL-B. Waveform features were then correlated with percent cover of coral morphologies, domed and branched, and total cover of …

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