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Deep Learning Beyond Traditional Supervision, Shixing Chen

Wayne State University Dissertations

With the rapid development of innovative models and huge success on various applications, the field of deep learning has attracted enormous attention in computer vision, machine learning, and artificial intelligence. Countless researches have validated the superior performance and unprecedented extensiveness of deep learning models, especially with the advantages of high performance computing by GPUs and parallel computation. Nonetheless, drawbacks including strong dependency on supervision (sufficient labeled data) and monotonous usage of categorized labels are negatively interfering the advancement of deep learning.

In this dissertation, we plan to expose and exploit some possibilities of deep learning without using data and labels …

Effect Of Tofacitinib On Patient-Reported Outcomes In Patients With Active Psoriatic Arthritis And An Inadequate Response To Tumour Necrosis Factor Inhibitors In The Phase Iii, Randomised Controlled Trial: Opal Beyond., Vibeke Strand, Kurt De Vlam, Jose A Covarrubias-Cobos, Philip Mease, Dafna D Gladman, Linda Chen, Elizabeth Kudlacz, Joseph Wu, Joseph C Cappelleri, Thijs Hendrikx, Ming-Ann Hsu

Articles, Abstracts, and Reports

Objectives: Tofacitinib is an oral Janus kinase inhibitor for treatment of psoriatic arthritis (PsA). Patient-reported outcomes (PROs) were evaluated in patients with PsA with inadequate responses to tumour necrosis factor inhibitors (TNFi-IR) in a 6-month, phase III randomised controlled trial (OPAL Beyond [NCT01882439]).

Methods: Patients (N=394) received tofacitinib 5 or 10 mg twice daily or placebo (advancing to tofacitinib 5 or 10 mg twice daily at month 3). Least squares mean changes from baseline and percentages of patients reporting improvements ≥minimum clinically important differences and scores ≥normative values were determined in Patient Global Assessment of disease activity (PtGA), Pain, Patient …

Advancing Urban Wildlife Research Through A Multi-City Collaboration, Seth B. Magle, Mason Fidino, Elizabeth W. Lehrer, Travis Gallo, Matthew P. Mulligan, María Jazmín Ríos, Adam A. Ahlers, Julia L. Angstmann, Amy Belaire, Barbara Dugelby, Ashley Gramza, Laurel Hartley, Brandon Macdougall, Travis J. Ryan, Carmen M. Salsbury, Heather Sander, Christopher Schell, Kelly Simon, Sarah St. Onge, David Drake

Scholarship and Professional Work - LAS

Research on urban wildlife can help promote coexistence and guide future interactions between humans and wildlife in developed regions, but most such investigations are limited to short-term, single-species studies, typically conducted within a single city. This restricted focus prevents scientists from recognizing global patterns and first principles regarding urban wildlife behavior and ecol- ogy. To overcome these limitations, we have designed a pioneering research network, the Urban Wildlife Information Network (UWIN), whereby partners collaborate across several cities to systematically collect data to populate long-term datasets on multiple species in urban areas. Data collected via UWIN support analyses that will enable …

Validating The 3d And 2d Mandibular Plane To The Frankfort Plane For Craniofacial Measurement, Jason Jyun-Chen Kuo, Ellen Wen-Ching Ko

Taiwanese Journal of Orthodontics

Purpose: This study evaluated whether the three-dimensional (3D) plane-to-plane mandibular plane angle measurement method could be applied in clinical analysis in a manner similar to the application of conventional two-dimensional (2D) cephalometric measurement, regardless of whether patients had symmetrical planes. Patients and methods: This retrospective study selected 30 patients who had undergone both lateral cephalometric radiography and cone beam computed tomography (CBCT). The 2D measurement was manually traced from the lateral cephalometric radiographs for the Frankfort horizontal plane line and mandibular plane line (2D FMA). The 3D reconstructions for each patient in the CBCT were evaluated using 3D software and …

Disease/Health/Medicine/History: On The Consolidation Of A Subfield Of Study, Diego Armus

History Faculty Works

This essay reviews the following works:

Medicine and Nation Building in the Americas, 1890–1940. By José Amador. Nashville: Vanderbilt University Press, 2015. Pp. ix + 219. $39.95 paperback. ISBN: 9780826520210.

Medicine and Public Health in Latin America: A History. By Marcos Cueto and Steven Palmer. New York: Cambridge University Press, 2015. Pp. ix + 306. $32.99 paperback. ISBN: 9781107633018.

A History of Family Planning in Twentieth-Century Peru. By Raúl Necochea López. Chapel Hill: University of North Carolina Press, 2014. Pp. xii + 234. $37.50 paperback. ISBN: 9781469618081.

Progressive Mothers, Better Babies: Race, Public Health, and the State in Brazil, 1850–1945. …

The Effects Of 8 Oz Of Fresh Vs. Commercial Orange Juice On Blood Pressure In Normotensive Males Aged 18-59, Cheng Yi Wong, Izac Dinio

Loma Linda University Research Reports

Background: Oranges have been known to possess numerous health benefits for humans as they are rich in vitamin C, A, and potassium. Citrus fruits contain a substance known as “citrus sinensis juice” which boosts immune function and aids in wound healing. Sinensis juice can also reduce blood pressure, inflammation, and risk of cardiovascular disease.

Objective: To determine the effects of drinking eight ounces of fresh vs. commercial orange juice on blood pressure in healthy normotensive males ages 18-59 years.

Design: Randomized, single-blinded, crossover study.

Participants: Healthy males aged 18-59 years, willing to keep the same lifestyle, …

Decoupling The Effects Of The Amyloid Precursor Protein From Amyloid-Β Plaques On Axonal Transport Dynamics In The Living Brain, Christopher S. Medina, Taylor W. Uselman, Daniel R. Barto, Frances Cháves, Russell E. Jacobs, Elaine L. Bearer

Pathology Research and Scholarship

Amyloid precursor protein (APP) is the precursor to Aβ plaques. The cytoplasmic domain of APP mediates attachment of vesicles to molecular motors for axonal transport. In APP-KO mice, transport of Mn2+ is decreased. In old transgenic mice expressing mutated human (APPSwInd) linked to Familial Alzheimer's Disease, with both expression of APPSwInd and plaques, the rate and destination of Mn2+ axonal transport is altered, as detected by time-lapse manganese-enhanced magnetic resonance imaging (MEMRI) of the brain in living mice. To determine the relative contribution of expression of APPSwInd versus plaque on transport dynamics, we developed a Tet-off system to decouple expression …

The Role Of Serum Histones In Canine Heat Stroke, Jenna Acutt

Scripps Senior Theses

Rising temperatures all over the world has correlated with more frequent heat stroke related injuries and death. This statistic not only applies to humans, but to canines as well, who have similar body temperature thresholds. Recent studies have demonstrated that serum histones, released after cell death from heat stroke, play a role in heat stroke related injuries and death. This proposal aims to determine the severity of the effects caused by serum histone release after heat stroke by exposing selected canine cell lines to cell lysate and purified histones H2A, H2B, H3, and H4, which have been found to be …

An Analysis And Critique Of Mental Health Treatment In American State Prisons And Proposal For Improved Care, Shelby Hayne

Scripps Senior Theses

Mental health treatment in state prisons is revealed to be highly variable, under-funded, and systematically inadequate. Existing literature exposes this injustice but fails to provide a comprehensive proposal for reform. This paper attempts to fill that gap, outlining a cost-effective, evidence-based treatment proposal, directly addressing the deficits in care revealed through analysis of our current system. In addition, this paper provides historical overviews of the prison system and mental health treatment, utilizing theoretical perspectives to contextualize this proposal in the present state of affairs. Lastly, the evidence is provided to emphasize the potential economic and social benefits of improving mental …

Face Off: An Examination Of State Biometric Privacy Statutes & Data Harm Remedies, Maya E. Rivera

Fordham Intellectual Property, Media and Entertainment Law Journal

As biometric authentication becomes an increasingly popular method of security among consumers, only three states currently have statutes detailing how such data may be collected, used, retained, and released. The Illinois Biometric Information Privacy Act is the only statute of the three that enshrines a private right of action for those who fail to properly handle biometric data. Both the Texas Capture or Use Biometric Identifier Act Information Act and the Washington Biometric Privacy Act allow for state Attorneys General to bring suit on behalf of aggrieved consumers. This Note examines these three statutes in the context of data security …

Rights To The River: Implementing A Social Cost-Benefit Analysis In The United States Hydropower Relicensing Process, Claire Wendle

Scripps Senior Theses

Private hydropower operations across the United States are utilizing a public resource, rivers, for power production benefits. The Federal Energy Regulatory Commission regulates river use through a relicensing procedure that occurs every thirty or fifty years through a cost-benefit analysis framework to determine the best public use of the river. This thesis explores the structure of the current cost-benefit analysis and the effects of timing, public participation and valuation of ecosystem services in the final relicensing decision, and recommends the use of a social cost-benefit framework to distribute the natural resource benefits rivers provide more equally and give fair weight …

The Effects Of An Early Motion Protocol For Rehabilitation Following A Massive Rotator Cuff Tear Repair: A Case Report, Kody Strum

Physical Therapy Scholarly Projects

Background and Purpose: Rotator cuff tears are one of the most common musculoskeletal injuries to occur in the United States. Following a surgical repair, there are two main rehabilitation protocols: early motion and delayed motion. Despite the large number of patients in need of rehab following a rotator cuff tear surgical repair, there is not yet a definitive answer in the literature as far as the best protocol to use.

Case Description: The patient was a 68-year-old male who injured himself while slipping and attempting to catch himself with his right arm. He presented to physical therapy following a surgical …

Using The Landing Error Scoring System (Less) To Predict The Risk Of Lower Extremity Injuries In Athletes, Marit Mikkelsen, Anthony Peterson, Travis Rinkenberger

Physical Therapy Scholarly Projects

Introduction: Athletes that participate in any sport are at an increased risk of injury, especially lower extremity injury. In particular, many athletes experience anterior cruciate ligament (ACL) injury during competition and practice sessions. The Landing Error Scoring System (LESS) is a tool used to identify athletes with a higher potential risk for ACL injury.

Purpose: The purpose of this study is to compare vertical jump landing mechanics between genders and among various sports.

Methods: Forty-one participants (21 females, 20 males) were recruited from a NCAA Division I university. Participants were from the following sports: football, volleyball, women’s soccer, and men’s …

A Behavioral Confirmation And Reduction Of The Natural Versus Synthetic Drug Bias, Brian P. Meier, Amanda J. Dillard, Eric S. Osorio, Courtney M. Lappas

Psychology Faculty Publications

Research reveals a biased preference for natural versus synthetic drugs; however, this research is based upon self-report and has not examined ways to reduce the bias. We examined these issues in five studies involving 1,125 participants. In a Pilot Study (N = 110), participants rated the term natural to be more positive than the term synthetic, which reveals a default natural-is-better belief. In Studies 1 (N = 109) and 2 (N = 100), after a supposed personality study, participants were offered a thank you “gift” of a natural or synthetic pain reliever. Approximately 86% (Study 1) and 93% (Study 2) …

The Importance Of Muslim Fathers In America, Brady Silva

Spectrum

No abstract provided.

The Beginning Of The End For Belugas In Captivity In The United States, Megan E. Boyd

Animal Law Review

Beluga whales have been displayed in aquariums and zoos for decades, but the end of captive beluga displays in the United States is near, thanks to Georgia Aquarium v. Pritzker. In 2012, the Georgia Aquarium, on behalf of members of the beluga cooperative breeding program, applied to the National Marine Fisheries Service (NMFS) for a special permit allowing the breeding cooperative to import eighteen beluga whales from Russia. After NMFS denied the permit, the Aquarium brought suit, arguing that NMFS’s denial was arbitrary and capricious and that without an influx of belugas, the United States captive beluga whale breeding program …

Animal Welfare Act: Excluded Animals, Michael Mcfadden, Sue Leary, Kathy Hessler

Animal Law Review

Michael McFadden discusses the Animal Welfare Act’s exclusion of farmed animals and possible reasons for their exclusion. He then briefly discusses welfare problems faced by farmed animals. He ends by describing the various ways in which consumers are showing increasing concern for farmed animals and how consumers, especially millennial consumers, are poised to force the agricultural industry to improve conditions for farmed animals. Sue Leary recounts the history of efforts to include rats, mice, and birds, in the AWA. Next, she explains the historical and contemporary issues with including common laboratory research animals under animal protection laws. She ends her …

2019-2020 Peter Morgane Student Research Fellowship, University Of New England College Of Osteopathic Medicine

Peter Morgane Research Fellowships

2019 recipients of the University of New England College of Osteopathic Medicine's Peter Morgane Research Fellowship.

Montanan, Winter 2019, University Of Montana--Missoula

Montanan Magazine, 1969-2024

This is the magazine of the University of Montana with news about the University for UM alumni as well as current faculty, students, staff, and administrators. This is volume 36, number 1.

Mathematical Modeling Of Type 1 Diabetes, Gianna Wu

HMC Senior Theses

Type 1 Diabetes (T1D) is an autoimmune disease where the pancreas produces little to no insulin, which is a hormone that regulates blood glucose levels. This happens because the immune system attacks (and kills) the beta cells of the pancreas, which are responsible for insulin production. Higher levels of glucose in the blood could have very negative, long term effects such as organ damage and blindness.

To date, T1D does not have a defined cause nor cure, and research for this disease is slow and difficult due to the invasive nature of T1D experimentation. Mathematical modeling provides an alternative approach …

Talking About Black Lives Matter And #Metoo, Linda S. Greene, Lolita Buckner Innes, Bridget J. Crawford, Mehrsa Baradaran, Bennett Capers, Osamudia R. James, Keisha Lindsay

Articles

No abstract provided.

First Amendment Law—The Regulation Of Religious Lobbyists: A Spiritual Battle For The Soul Of Democracy, Nicholas Melvin Smith

Western New England Law Review

Governmental transparency is among the most fundamental requirements of a democracy. This belief is the backbone of codes of ethics amongst both states and the federal government. Codes of ethics universally apply to state employees, as well as those attempting to influence policy. We call these influencers lobbyists. Every state regulates the actions of lobbyists. Some states have broad, sweeping language that requires lobbyists to report a great deal of information to the state, which is then made public to voters, while other states allow for express exemptions to keep certain actions out of the public eye.

Because the federal …

The Economics Of Honey Bee (Hymenoptera: Apidae) Management And Overwintering Strategies For Colonies Used To Pollinate Almonds, Gloria Degrandi-Hoffman, Henry Graham, Fabiana Ahumada, Matthew Smart, Nick Ziolkowski

Department of Entomology: Faculty Publications

Commercial honey bee (Apis mellifera L.) colonies significantly contribute to agricultural productivity through crop pollination. Almond production requires the most colonies because there are more than a million acres of orchards that require cross-pollination for nut set. With the rising costs of managing and transporting colonies to almond orchards combined with the high colony losses beekeepers routinely experience, we asked if renting colonies for almond pollination was profitable. We conducted a longitudinal study on 190 colonies from their establishment in April until they were placed in almond orchards 10 mo later. In the fall, equal numbers of colonies were placed …

Development Of A Procedure To Measure The Performance Of Ventilation Filters For Nanoparticles, A. Bahloul, C. Brochot, P. Abdolghader, F. Haghighat

Résumés de conférences

No abstract provided.

Spiking Network Optimized For Word Recognition In Noise Predicts Auditory System Hierarchy, Seyedeh Fatemeh Khatami, Monty Escabí

All Faculty Articles - School of Engineering and Computer Science

The auditory neural code is resilient to acoustic variability and capable of recognizing sounds amongst competing sound sources, yet, the transformations enabling noise robust abilities are largely unknown. We report that a hierarchical spiking neural network (HSNN) optimized to maximize word recognition accuracy in noise and multiple talkers predicts organizational hierarchy of the ascending auditory pathway. Comparisons with data from auditory nerve, midbrain, thalamus and cortex reveals that the optimal HSNN predicts several transformations of the ascending auditory pathway including a sequential loss of temporal resolution and synchronization ability, increasing sparseness, and selectivity. The optimal organizational scheme enhances performance by …

“Being On Ssi Is A Full-Time Job:” How Ssi And Ssdi Beneficiaries Work Around And Within Labor Incentive Programs, Katie Savin

All Faculty Scholarship

Background and Purpose: Disabled individuals, their families, and communities are more likely to live in poverty than their non-disabled counterparts. The Social Security Administration (SSA) is social safety net that provides cash assistance programs through social insurance (Social Security Disability Insurance, or SSDI) and public assistance (Supplemental Security Income, or SSI) programs to people who meet eligibility criteria. The SSA offers work incentive programs that encourage enrolled disabled people to return to the workforce yet has found that these programs are infrequently utilized. This research aims to fill both knowledge and methodological gaps in the literature on why those support …

Who Defines My Quality Of Life? Perspectives From People With Developmental Disabilities And Their Caregivers, M. Chris-Cooper, Katie Savin, P. Mejia, J. Cummins

All Faculty Scholarship

No abstract provided.

Evolution Of Portulacineae Marked By Gene Tree Conflict And Gene Family Expansion Associated With Adaptation To Harsh Environments, Ning Wang, Ya Yang, Michael J. Moore, Samuel F. Brockington, Joseph F. Walker, Joseph W. Brown, Bin Liang, Tao Feng, Caroline Edwards, Jessica Mikenas, Julia E. Olivieri, Vera Hutchison, Alfonso Timoneda, Tommy Stoughton, Raúl Puente, Lucas C. Majure, Urs Eggli, Stephen A. Smith

All Faculty Articles - School of Engineering and Computer Science

Several plant lineages have evolved adaptations that allow survival in extreme and harsh environments including many families within the plant clade Portulacineae (Caryophyllales) such as the Cactaceae, Didiereaceae, and Montiaceae. Here, using newly generated transcriptomic data, we reconstructed the phylogeny of Portulacineae and examined potential correlates between molecular evolution and adaptation to harsh environments. Our phylogenetic results were largely congruent with previous analyses, but we identified several early diverging nodes characterized by extensive gene tree conflict. For particularly contentious nodes, we present detailed information about the phylogenetic signal for alternative relationships. We also analyzed the frequency of gene duplications, confirmed …

External Marking And Behavior Of Early Instar Helicoverpa Armigera (Lepidoptera: Noctuidae) On Soybean, Luiz E. R. Pannuti, Edson L. L. Baldin, Silvana L. Vieira De Paula Moraes, Thomas E. Hunt, Vinicius F. Canassa, José P. F. Bentivenha, Ivana F. Da Silva

Department of Entomology: Faculty Publications

Helicoverpa armigera Hübner (Lepidoptera: Noctuidae) is a pest of major agricultural crops, such as soybean and cotton. A better understanding of larval movement is important for its integrated management and resistance management. Studies with neonates through second instar larvae are still limited by the difficulties involving the handling and observation of these instars. Many studies require marking larvae, and most research involving marking is focused on moths. However, our study investigated aspects of larval behavior of the second instar of H. armigera on soybean plants. The dyes luminous powder red and Sudan Red 7B were tested as external larval …

Developmental Parameters Of Spodoptera Frugiperda (Lepidoptera: Noctuidae) Immature Stages Under Controlled And Standardized Conditions, Débora Goulart Montezano, Alexandre Specht, Daniel Ricardo Sosa-Gomez, Vânia Ferreira Roque-Specht, Silvana L. Vieira De Paula Moraes, Julie A. Peterson, Thomas E. Hunt

Department of Entomology: Faculty Publications

The fall armyworm, Spodoptera frugiperda (J. E. Smith, 1797), is the most important noctuid pest in the Americas and has recently become an invasive pest in Africa and in India. Having a detailed and standardized record of the biology and the larval development of S. frugiperda will be critical to further studies on integrated pest management, toxicology, and applied ecology. This study reports the temporal and morphological parameters of the immature stages of S. frugiperda for larvae fed on artificial diet under controlled conditions (25 ± 1 °C, 70 ± 10% RH and 14 hour photophase). The survival …