Digital Commons Network^™

Characteristics Of Cause Of Death, Victim, Crime, Offender, And Familial Relationship, William J. Reilly

Walden Dissertations and Doctoral Studies

Broad personality or global traits are unlikely to assist in solving capital crimes, so forensic psychologists have begun to focus on characteristics of the crime to create differentiating profiles. The purpose of this study was to determine if offender and victim characteristics and method of murder could provide cluster profiles differentiating familial relationship between offender and victim. Guided by classical conditioning theory and social learning theory, an archival database of 147 capital offenders responsible for 506 victims was analyzed. Cluster analysis yielded 3 distinct profiles. Compared to other clusters, Cluster 1 offenders tended to be Black and unfamiliar with their …

Utilizing Food Safety Knowledge In Comprehensive Patient Care Among Harlem Hospital Physicians, Sean Alexander Shivers

Walden Dissertations and Doctoral Studies

According to the World Health Organization (WHO), people throughout the world become sick every year from consuming contaminated foods, which impacts countries’ socioeconomic development, straining their healthcare system, travel and tourism, and foreign trade markets. To help alleviate the impact foodborne illness (FBI) has on society, scholars suggest physicians incorporate food safety in their standard work practice. The purpose of this study was to determine if Harlem Hospital physicians utilized food safety knowledge in comprehensive patient care with a diagnosis of FBI, in addition to how physicians passed this food safety information onto the patient. A qualitative methodology using an …

Repercussions Of The Mechanistic Dehumanization Of Muslim Americans, Resilience, And Sustainable Communities, Melvin Walters

Walden Dissertations and Doctoral Studies

There is a lack of research on the relationship between dehumanization of minority religious groups and affiliation with terrorism, which suggests a need to consider the consequences of dehumanization perceptions beyond promoting aggression. This qualitative case study addresses whether dehumanization embedded in public policies influences Muslim Americans 18 to 25 years of age, native and nonnative, to engage in homegrown terrorism. Using Schneider and Ingram’s social constructions of target populations as the foundation, research questions focused on how perceptions of mechanistic dehumanization in policy design influence homegrown terrorism among Muslim- American adults. Data were acquired through archival data that included …

The Impact Of Campus Health Services On The Attitudes, Perceptions, Beliefs, And Behaviors Of Historically Black College And University Students, Micah Mccray Griffin

Walden Dissertations and Doctoral Studies

African Americans suffer worse health outcomes related to chronic disease than any other racial or ethnic group. The negative effects associated with poor dietary habits and a low propensity to exercise impact young adult African Americans who attend Historically Black Colleges/Universities (HBCUs) and can lead to higher mortality rates. It is important for HBCU campus health centers to address the perceptions and beliefs of students to positively impact health behaviors associated with diet and exercise. At the time of this study, there was limited research on-campus health centers and their impact on HBCU student health beliefs and behaviors. Therefore, this …

Predictive Factors Of Drug Court Completion For Female Participants, Shannon Jordan

Walden Dissertations and Doctoral Studies

Women comprise one of the fastest growing populations of the criminal justice system, yet little research exists concerning the success of these women completing a coed pretrial drug court diversion program. Trauma theory was applied to inform the variables in this quantitative correlational study. The predictive nature of age, educational level, marital status, violent criminal history, and mental health problems for women were examined in relation to completion of a coed pretrial drug court diversion program. A convenience sample from secondary, archival data was obtained from a criminal justice agency in Washington, DC. The dataset included women who participated in …

Mobile Devices In Higher Education: Faculty Perception In The United Arab Emirates, Shameen Sucrine Monteiro

Walden Dissertations and Doctoral Studies

Research has been conducted on the effectiveness of mobile devices in education; however, few scholars have addressed how faculty members perceive the use of mobile devices in the classroom. Mobile devices in higher education have the potential to support innovative teaching modalities. The purpose of this qualitative case study was to explore faculty perceptions of using the mobile device as an instructional aid in a higher educational institution in the United Arab Emirates (UAE). The conceptual framework was Zhao and Frank's metaphorical use of ecology and the ecosystem. Three research questions focused on faculty members' perceptions of uses, challenges, and …

Mothers' Parenting Discipline Style And Their Early Puberty Daughters' Engagement In High-Risk Behaviors, Yvette C. White

Walden Dissertations and Doctoral Studies

Some early puberty girls engage in high-risk externalizing behaviors such as early sexual activity, delinquent behavior, and disruptive behaviors. Harsh parenting experienced by girls who develop early has been associated with delinquent and disruptive behaviors. The purpose of this quantitative correlational study was to examine predictive relationships between the style of parental discipline by mothers of early puberty girls and the likelihood and frequency of the girls' engagement in high-risk behaviors. Parenting style theory, including the authoritarian, authoritative, and permissive style of parenting, served as the theoretical foundation for the study. Survey data were collected from 28 mothers who identified …

Predictive Relationship Between Socio-Demographics, Medication, And Treatment Completion Among Persons Experiencing Homelessness Treated For Tuberculosis, Sophia Ajoku

Walden Dissertations and Doctoral Studies

Approximately 80% of people who contract tuberculosis (TB) in the United States are first infected with untreated latent tuberculosis infection (LTBI). LTBI is an ongoing public health concern in people who experience homelessness. Because of the transient nature of this population, it is often difficult for them to adhere to and complete treatment for LTBI. In this quantitative, correlational of a cross-sectional study, secondary data was from a public health clinic in southern U.S. The theoretical framework used for the study was the social ecological framework. Multiple logistic regression was used to determine if a statistically significant predictive relationship existed …

The Role Of Online Support For Anaplastic Thyroid Cancer Patients And Survivors, Bevin J. Nixon

Walden Dissertations and Doctoral Studies

The rate of thyroid cancer diagnosis has risen, and researchers' findings point to improved diagnostic testing and overdiagnosis as well as increases in actual incidences as the reasons behind this rise. With improved treatments and testing methods, the number of thyroid cancer survivors has also increased. Thyroid cancer presents challenges to coping and can cause significant stress in an individual's life. More specifically, anaplastic thyroid cancer (ATC) creates complicated challenges for patients and survivors. The problem is patients need support during diagnosis and treatment when adjusting to their 'new normal' and may be reaching to Internet based social support groups …

The Psychological Impact Of Testosterone Replacement Therapy In Middle-Aged Men, Gregory E. Coles Sr.

Walden Dissertations and Doctoral Studies

Decreased testosterone levels (hypogonadism) in middle-aged men (aged 45-64) has been associated with increased levels of depression. Studies have suggested that increases in anxiety and/or attention problems may also be associated with hypogonadism but have not provided empirical evidence to support these suggestions. The purpose of this quantitative study was to examine depression, anxiety, and attention problems in middle-aged men using a psychological self-report inventory. The theoretical model used in this study was the biomedical model, which combined pharmacological treatment with psychological self-report inventories to determine if there was an association or relationship between the testosterone levels in men and …

Some Current Trends And Challenges In Philippine Aquaculture, With An Emphasis On Synergies With Biodiversity Initiatives, Ronald Allan L. Cruz, Vikas Kumar, Janice A. Ragaza

Biology Faculty Publications

No abstract provided.

A Rapid And Accurate Minion-Based Workflow For Tracking Species Biodiversity In The Field, Hendrik Freitag, Simone Maestri, Emanuela Cosentino, Marta Paterno, Jhoana M. Garces, Luca Marcolungo, Massimiliano Alfano, Iva Njunjić, Menno Schilthuizen, Ferry Slik, Michele Menegon, Marzia Rossato, Massimo Delledonne

Biology Faculty Publications

Genetic markers (DNA barcodes) are often used to support and confirm species identification. Barcode sequences can be generated in the field using portable systems based on the Oxford Nanopore Technologies (ONT) MinION sequencer. However, to achieve a broader application, current proof-of-principle workflows for on-site barcoding analysis must be standardized to ensure a reliable and robust performance under suboptimal field conditions without increasing costs. Here, we demonstrate the implementation of a new on-site workflow for DNA extraction, PCR-based barcoding, and the generation of consensus sequences. The portable laboratory features inexpensive instruments that can be carried as hand luggage and uses standard …

How Have Advances In Ct Dosimetry Software Impacted Estimates Of Ct Radiation Dose And Cancer Incidence? A Comparison Of Ct Dosimetry Software: Implications For Past And Future Research, Susannah Maxwell, Richard Fox, Donald Mcrobbie, Max Bulsara, Jenny Doust, Peter O'Leary, John Slavotinek, John Stubbs, Rachael Moorin

Health Sciences Papers and Journal Articles

Objective: Organ radiation dose from a CT scan, calculated by CT dosimetry software, can be combined with cancer risk data to estimate cancer incidence resulting from CT exposure. We aim to determine to what extent the use of improved anatomical representation of the adult human body “phantom” in CT dosimetry software impacts estimates of radiation dose and cancer incidence, to inform comparison of past and future research.

Methods: We collected 20 adult cases for each of three CT protocols (abdomen/pelvis, chest and head) from each of five public hospitals (random sample) (January-April inclusive 2010) and three private clinics (self-report). Organ …

Proteomic Analysis Of Plasmodium Falciparum Histone Deacetylase 1 Complex Proteins, Jessica A. Engel, Emma L. Norris, Paul Gilson, Jude Przyborski, Addmore Shonhai, Gregory L. Blatch, Tina S. Skinner, Jeffrey Gorman, Madeleine Headlam, Katherine T. Andrews

Health Sciences Papers and Journal Articles

Plasmodium falciparum histone deacetylases (PfHDACs) are an important class of epigenetic regulators that alter protein lysine acetylation, contributing to regulation of gene expression and normal parasite growth and development. PfHDACs are therefore under investigation as drug targets for malaria. Despite this, our understanding of the biological roles of these enzymes is only just beginning to emerge. In higher eukaryotes, HDACs function as part of multi-protein complexes and act on both histone and non-histone substrates. Here, we present a proteomics analysis of PfHDAC1 immunoprecipitates, identifying 26 putative P. falciparum complex proteins in trophozoite-stage asexual intraerythrocytic parasites. The …

Metabolic Effects Of 17a-Estradiol Are Growth Hormone Independent And Sex Specific, Silvana Sidhom

Electronic Theses and Dissertations

Aging is a major risk factor for metabolic syndromes and type two diabetes. With growing elderly populations worldwide and increasing incidence of age-related diseases there is a great need to develop pharmacological interventions that would delay aging and protect from age-related diseases. 17-alpha estradiol (17α-E2) is an epimer of the primary female sex hormone estradiol and has been shown to extend lifespan and downregulate markers of age-related metabolic dysfunction in male mice. Because 17α-E2 does not induce feminization in males it holds potential as a novel therapeutic in humans for age-related metabolic dysfunction. Importantly, we have previously shown that 17α-E2 …

Mechanism Of Nanogp8 In Glioblastoma Multiforme, Jonhoi Smith

Electronic Theses and Dissertations

Glioblastoma multiforme (GBM) is an incurable brain tumor, with patients only expecting to live 15 to 16 months post-diagnosis with the most current treatments options including surgery, chemotherapy, and radiation. How GBM resist treatment is still not very well known. However, cancer stem cells (CSCs), a subset of cells in GBM tissue considered responsible for therapeutic resistance and the poor patient prognosis. NANOG, a homeobox gene, is responsible for maintaining pluripotency of embryonic stem cells and is observed in CSCs. NANOGP8, a retrogene in the NANOG family is expressed in CSCs and provides cells with stem-like characteristics previously observed in …

Identification And Functional Characterization Of A Long Non-Coding Rna Associated With Prostate Cancer, Md Faqrul Hasan

Electronic Theses and Dissertations

Prostate cancer is the most common cancer in men in the western world. Although early stage prostate cancer is treatable late stage, more specifically, metastatic and drug resistant prostate cancers are mostly incurable. The failure of current treatments obligates the research community to explore novel areas in prostate cancer biology and find better therapeutic targets. Emerging evidences show that non-coding RNAs specifically long non-coding RNAs (lncRNAs) play regulatory roles in various cellular processes and are frequently dysregulated in cancer including prostate cancer. These aberrantly expressed lncRNAs mostly with unexplored genetic information may drive cancer progression. Previous studies done in our …

Development Of A Functional Testing Platform For The Sensory Segment Of The Neuromuscular Reflex Arc, Alisha Colon

Electronic Theses and Dissertations

Investigations of human biology and disease have been hindered by the use of animal models. The information obtained from such studies often results in clinically irrelevant results and drug trial failures. Additionally, several governing bodies have been formulating legislation to move away from animal models and toward more ethical and efficient testing platforms for drug discovery and cosmetic research. As an answer to these issues, "body-on-a-chip" systems have been a rapidly developing field which easily recapitulates in vivo functionality, providing a more relevant, repeatable, and ethical testing platform to better predict biology. These systems can be used as human-based testing …

Human-Wildlife Conflict And Coexistence In A More-Than-Human World: A Multiple Case Study Exploring The Human-Elephant-Conservation Nexus In Namibia And Sri Lanka, Cynthia Castaldo-Walsh

Department of Conflict Resolution Studies Theses and Dissertations

This qualitative multiple case study explored human-elephant conflict-coexistence relationships and issues of conservation in Namibia (Damaraland) and Sri Lanka (Wasgamuwa) from a posthumanist, multispecies perspective. Within each region, conflict between humans and elephants is considered high, elephants are considered endangered and are of high conservation priority, the human population has grown significantly, and community-based organizations are implementing holistic approaches to increase positive relations between humans and elephants. This study was guided by research questions that explored the current landscape of the human-elephant-conservation nexus within each region, the shared histories between humans and elephants over time, and the value in utilizing …

Post-Decisional Conflict In Selecting Cancer Treatments: Perception Of Information Disclosure May Influence Decisional Conflict, Decisional Regret, And Self-Acceptance In Bereaved Parents Of Children With Cancer, Danielle De Santis Sperandeo

Department of Conflict Resolution Studies Theses and Dissertations

This study aimed to establish a connection, if any, between perceptions of information disclosure about medical treatment and decisional conflict in bereaved parents of children with cancer. Decisional regret was an important theme in this exploration because decisional conflict strongly aligns with the propensity to mentally redo past events, thereby forming counterfactual alternatives to reality. People generate counterfactuals to hypothesize a more favorable outcome subsequent to a negative event or the death of a child as applicable to this study. A secondary objective was to investigate the potential influence of counterfactual processing and regret on the construct of self-acceptance: a …

The Political Animal: The Animal Rights Movement And Public Policy, Dorothy Jean Simnett

Department of Conflict Resolution Studies Theses and Dissertations

Social movements are consequences of social conflict. This project examines the conflicting and contentious efforts of animal rights activists at changing public policy and it evaluates the successes and failures of the animal rights movement. Animal rights activists’ challenges concerning animal rights, animal welfare and animal protection, combined with divergences from the special interest consortiums compounded by societal norms will all be addressed here. Furthermore, none of this has been previously addressed in the field of Conflict Resolution. This project highlights the challenges that animal rights advocates encounter when attempting to safeguard animal protective measures. The power struggle between animal …

Covert Singing In Anticipatory Auditory Imagery, Tim A. Pruitt, Andrea R. Halpern, P. Q. Pfordresher

Faculty Journal Articles

To date, several fMRI studies reveal activation in motor planning areas during musical auditory imagery. We addressed whether such activations may give rise to peripheral motor activity, termed subvocalization or covert singing, using surface electromyography. sensors placed on extrinsic laryngeal muscles, facial muscles, and a control site on the bicep measured muscle activity during auditory imagery that preceded singing, as well as during the completion of a visual imagery task. Greater activation was found in laryngeal and lip muscles for auditory than for visual imagery tasks, whereas no differences across tasks were found for other sensors. Furthermore, less accurate singers …

The Socialization Of Female Hostage Negotiators: Their Voices, Perspectives, & Experiences, Lieutenant Superville

Department of Conflict Resolution Studies Theses and Dissertations

In its fifth annual study, the National Center for Women and Policing reported that women continue to face widespread bias in police hiring and are under-represented because of biased selection practices and recruitment policies that keep their number artificially low. Once hired, women face discrimination, harassment, intimidation, and are maliciously thwarted as they move up the ranks. With respect to gender and organizational culture, the NCWP study failed to capture and describe the perceptions and socialization experiences of those who moved up into the specialized units, particularly female hostage negotiators. For this reason, the current study was designed to examine …

A Case Study Of Crisis Management Training Needs: Saudi Airlines, Hussain Saad Alqahtani

Department of Conflict Resolution Studies Theses and Dissertations

This dissertation explores crisis management policies, programs, and training in the Kingdom of Saudi Arabia’s premier airliners, Saudi Arabian Airlines. Saudi Arabian Airlines is a domestic and international carrier with a major role in the transportation of millions of Muslim pilgrims to the Kingdom during the annual Hajj season. This event places enormous strains on the capacity of the carrier, the airport, ground support systems, and the societal infrastructure of country. There have been tireless efforts by the Airline’s staffers to serve millions of visitors including pilgrims in a timely, safe and appropriate manner. Crisis management for Saudi Arabian Airlines …

Conflict, Stress And Faith Experienced By Caregivers Of Bipolar Family Members, Sharonrose Bollers

Department of Conflict Resolution Studies Theses and Dissertations

Mental health issues present challenges to the mentally ill, and to the family members who are their caregivers. Among the challenges faced by caregivers are conflict and stress. This transcendental phenomenological study explored the experiences and perceptions of caregivers of conflict, stress, and the role of faith. In addition, this study sought to learn what lessons and strategies caregivers utilized and often created while caring for their family member with bipolar disorder. In this study ten caregivers were interviewed, telephonically or face-to-face, using a semi-structured interview format. Coming from four states, some were employed, some were retired, and one was …

Unmanned Aerial System And Satellite-Based High Resolution Imagery For High-Throughput Phenotyping In Dry Bean, Sindhu Sankaran, Juan José Quirós, Phillip N. Miklas

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Dry bean breeding programs are crucial to improve the productivity and resistance to biotic and abiotic stress. Phenotyping is a key process in breeding that refers to crop trait evaluation. In recent years, high-throughput plant phenotyping methods are being developed to increase the accuracy and efficiency for crop trait evaluations. In this study, aerial imagery at different resolutions were evaluated to phenotype crop performance and phenological traits using genotypes from two breeding panels, Durango Diversity Panel (DDP) and Andean Diversity Panel (ADP). The unmanned aerial system (UAS) based multispectral and thermal data were collected for two seasons at multiple time …

Divergent Antigen-Specific Cellular Immune Responses During Asymptomatic Subclinical And Clinical States Of Disease In Cows Naturally Infected With Mycobacterium Avium Subsp. Paratuberculosis, Judith R. Stabel, J. P. Bannantine

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Infection of the host with Mycobacterium avium subsp. paratuberculosis results in chronic and progressive enteritis that traverses both subclinical and clinical stages. The mechanism(s) for the shift from an asymptomatic subclinical disease state to advanced clinical disease is not fully understood. In the present study, naturally infected dairy cattle were divided into subclinical and clinical infection groups, along with noninfected control cows of similar parity, to study host immune responses in different stages of infection. Both infection groups had higher levels of secretion of gamma interferon (IFN-􏰇), tumor necrosis factor-alpha (TNF-􏰈), and interleukin-2 (IL-2) than control cows, whereas only clinical …

Race, Slavery And Justice: A Justice System Case Study, Camille Cameron

Reports & Public Policy Documents

We do not have to look far today in Canada to see the legacies of slavery in their full effect. One of these legacies is the way in which we have chosen to forget slavery, or perhaps to deny it, and to create a different narrative. “Slavery is Canada’s best-kept secret, locked within the national closet,” asserts Afua Cooper. Ask many Canadians about the history of slavery in Canada and they will talk about the Underground Railroad. This is what many of us learned in school, that slavery existed in America, not in Canada, and that Canada’s heroic, romantic role …

Filling The Gaps: Common Bottlenose Dolphin (Tursiops Truncatus) Population Dynamics, Structure, And Connectivity Within Florida Panhandle Bays, Sounds, And Estuaries, Christina Toms

Electronic Theses and Dissertations

At the time of the Deepwater Horizon oil spill in 2010, very little was known about the inshore bottlenose dolphin (Tursiops truncatus) populations hit hardest by the spill. Without previous population demographic data impacts were challenging to assess. My dissertation was designed to build research capacity moving forward by helping to fill data gaps in the western Florida Panhandle. The first study presented here resulted in the first system-wide assessment of seasonal abundance, survival, and site fidelity patterns of bottlenose dolphins that inhabit the Pensacola Bay system. In contrast to a previous study that reported only 33 dolphins, results from …

The Role Of Nrf2 Signalling In Cell Proliferation And Tumorigenesis Of Chromium Transformed Human Bronchial Epithelial Cells, Marco Antonio De Freitas Clementino

Theses and Dissertations--Toxicology and Cancer Biology

Hexavalent Chromium (Cr(VI) induces malignant cell transformation in normal bronchial epithelial (BEAS-2B) cells. Cr(VI)-transformed cells exhibit increased level of antioxidants, are resistant to apoptosis, and are tumorigenic. RNAseq analysis in Cr(VI)-transformed cells showed that expression of transcripts associated with mitochondrial oxidative phosphorylation is reduced, and the expression of transcripts associated with pentose phosphate pathway, glycolysis, and glutaminolysis are increased. Sirtuin-3 (SIRT3) regulates mitochondrial adaptive response to stress, such as metabolic reprogramming and antioxidant defense mechanisms. SIRT3 was upregulated and it positively regulated mitochondrial oxidative phosphorylation in Cr(VI)-transformed cells. Our results suggests that SIRT3 plays an important role in mitophagy deficiency …