Digital Commons Network^™

Shear Force Fiber Spinning: Process Parameter And Polymer Solution Property Considerations, Arzan C. Dotivala, Kavya P. Puthuveetil, Christina Tang

Chemical and Life Science Engineering Publications

For application of polymer nanofibers (e.g., sensors, and scaffolds to study cell behavior) it is important to control the spatial orientation of the fibers. We compare the ability to align and pattern fibers using shear force fiber spinning, i.e. contacting a drop of polymer solution with a rotating collector to mechanically draw a fiber, with electrospinning onto a rotating drum. Using polystyrene as a model system, we observe that the fiber spacing using shear force fiber spinning was more uniform than electrospinning with the rotating drum with relative standard deviations of 18% and 39%, respectively. Importantly, the approaches are complementary …

Rapid, Single-Step Protein Encapsulation Via Flash Nanoprecipitation, Shani L. Levit, Rebecca C. Walker, Christina Tang

Chemical and Life Science Engineering Publications

Flash NanoPrecipitation (FNP) is a rapid method for encapsulating hydrophobic materials in polymer nanoparticles with high loading capacity. Encapsulating biologics such as proteins remains a challenge due to their low hydrophobicity (logP < 6) and current methods require multiple processing steps. In this work, we report rapid, single-step protein encapsulation via FNP using bovine serum albumin (BSA) as a model protein. Nanoparticle formation involves complexation and precipitation of protein with tannic acid and stabilization with a cationic polyelectrolyte. Nanoparticle self-assembly is driven by hydrogen bonding and electrostatic interactions. Using this approach, high encapsulation efficiency (up to ~80%) of protein can be achieved. The resulting nanoparticles are stable at physiological pH and ionic strength. Overall, FNP is a rapid, efficient platform for encapsulating proteins for various applications.

Identifying Important Parameters In The Inflammatory Process With A Mathematical Model Of Immune Cell Influx And Macrophage Polarization, Marcella Torres, Jing Wang, Paul J. Yannie, Shobha Ghosh, Rebecca A. Segal, Angela M. Reynolds

Mathematics and Applied Mathematics Publications

In an inflammatory setting, macrophages can be polarized to an inflammatory M1 phenotype or to an anti-inflammatory M2 phenotype, as well as existing on a spectrum between these two extremes. Dysfunction of this phenotypic switch can result in a population imbalance that leads to chronic wounds or disease due to unresolved inflammation. Therapeutic interventions that target macrophages have therefore been proposed and implemented in diseases that feature chronic inflammation such as diabetes mellitus and atherosclerosis. We have developed a model for the sequential influx of immune cells in the peritoneal cavity in response to a bacterial stimulus that includes macrophage …

A Not-So Beautiful Mind: A Review Of The Genetics Of Schizophrenia, Lydia Pack

Oswald Research and Creativity Competition

Schizophrenia is often called “the cancer of the brain” because of the lifelong, horrendous implications of the disease. Though research has been conducted on schizophrenia for a century or more, it has just recently been realized how large a role genetics may play in the development of the disease. This review will discuss why research on schizophrenia genes has been difficult, what genes have been found, how the current treatments are being revolutionized, and how to progress in this field. The difficulty in research is due in part to the complex genetics behind the disease as well as possible environmental …

Increasing Warm-Season Native Grass Biomass Using Fire, Herbicide, And Nitrogen Applications, Sharon A. Clay, Alexander Smart, David E. Clay

Native Plant Focused Publications

The North American Great Plains tallgrass prairie was once a system of native cool and warm season grasses, which have been degraded by non-native invasive plants. Native grass restoration is highly desirable to improve ecosystem functions and productivity. In this two-year study, the impact of fire, herbicide, and nitrogen on productivity and the presence of invasive species [primarily the cool season grass, smooth brome (Bromus inermis Leyss.)] and native warm season native grass species [big bluestem (Andropogon gerardii Vitman), sideoats and blue grama (Bouteloua curtipendula (Michx.) Torr.), and B. gracilis (Willd. Ex Kunth) Lag. ex Griffiths] were investigated. Spring fire …

A Place Through Time, Vincent Argentina

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Structure-Function Analysis Of Inorganic Pyrophosphatase From Thermus Thioreducens, Joseph Ng

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Alteration In Capsaicin Levels In Peppers Using Gibberellin, Cytokinin And Auxin Plant Growth Regulators, Lawana Adcock-Downey

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Enhanced Stimulation Of Plant Root Growth In Hydroponic Systems Using Blue And Red Flourescent Light, Lawana Adcock-Downey

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Identifying Biomarkers For Post-Traumatic Stress Disorder (Ptsd) In Humans, Joseph Ng

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Isolation Of Mutant Bacteria That Sense Amino Acids From The Enviroment, Luis R. Cruz-Vera

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Regulation Of Plasmid Conjugation In Uropathogenic Escherichia Coli, Tanya Sysoeva

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Assessing The Status Subterranean Biodiversity At Shelta Cave In Huntsville: Traditional Surveys And Examining The Persistence And Efficacy Of Enviromental Dna, Matthew L. Niemiller

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Quantify Changes In The Glyclosis Metabollic Cycle Revelant To Diabtede Using A Rat Model, Bernhard Vogler

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Metabolomics To Quantify Cahnges In The Tca Cycle Relevant To Diabetes Using A Rat Model, Bernhard Vogler

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Efficacy Testing Of Nanotherapeutic Against Multi Drug Resistant Psuedomonas, Surangi Jayawardena

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Quantum Dots As A Tool For Rapid Point-Of-Care Diagnostics Of Clamydia, Surangi Jayawardena

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Synthesis Of Photcoupling Heterobifunctional Linkers For Nanomaterial Surface Functionalization, Surangi Jayawardena

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Targeted Antibacterial Therpeutics For Multi Drug Resistant Pseudomonas Aeruginosa, Surangi Jayawardena

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Comparing Glucose Tolerance In The Lew.1wr1 And Wistar Furth Rat, Sharifa T. Love-Rutledge

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Network And Agent-Based Modeling For Complex System Studies, Leonard Petnga

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Almost Periodically Forced Sigmoid Beverton-Holt Models, Toka Diagana

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

Genetic Level Of Penetration And Expressivity In Factors For Type Of Hemophilia, Hemoglobin, Aptt And Genotype, Naser Kamberi, Hyzer Rizani

Conference Presentations

This study investigates the penetration and genetic expression of factor VIII of hemophilia to individuals who are in the fourth degree of kinship from the mother’s line. So it comes to two hemophiliac brothers and a hemophiliac cousin whose mothers are sisters but who are married in different families. For these cases of hemophiliacs were performed laboratory, biochemical and genetic analyzes to observe the level of penetration and expression of factor VIII. We will present with the help of the genetic tree the origins or gene genealogies of the gene for this disease. Based on biochemical and genetic analysis using …

Han Shan’S Transparent Eyeball: The Asian Roots Of American Eco-Poetry, Tony Barnstone

English

No abstract provided.

The Repatriation Of The Palaeoamericans: Kennewick Man/The Ancient One And The End Of A Non-Indian Ancient North America, Ann M. Kakaliouras

Anthropology

This article considers the repatriation of some the most ancient human skeletal remains from the United States as two sorts of ending: their end as objects of scientific study, and their end as ancient non-American Indian settlers of North America. In the 1990s, some prominent physical anthropologists and archaeologists began replacing ‘Palaeoindian’ with the new category of ‘Palaeoamerican’ to characterize the western hemisphere's earliest inhabitants. Kennewick Man/the Ancient One, a nearly nine-thousand-year-old skeleton, convinced some anthropologists that contemporary Native American people (descendants of Palaeoindians) were not biologically related to the very first American colonists. The concept of the Palaeoamerican therefore …

Southern Accent September 2018 - April 2019, Southern Adventist University

Southern Accent - Student Newspaper

Southern Adventist University's newspaper, Southern Accent, for the 2018-2019 academic year.

Effect Of Aflibercept On Macular Retinal Layers And Peripheral Non Perfusion In Subjects With Proliferative Diabetic Retinopathy, Swetha Bindu Velaga

Student Theses, Dissertations and Capstones

Background: The relation between UWF fluorescein angiography (FA) and retinal non-perfusion were studied previously. The relationship between retinal thickness and retinal non-perfusion in subjects with diabetic retinopathy has not been studied using SD-OCT and UWF. Thus, in this current study we used SD-OCT to visualize the individual layers of retina and to evaluate whether the extent of non-perfusion is correlated with macular retinal layer thickness in subjects with PDR with no diabetic macular edema.

Methods: In this prospective longitudinal multicenter, randomized study a total of 36 eyes of thirty six subjects were included in final analysis. Subjects with any history …

Practice Makes The Deficiency Of Global Motion Detection In People With Pattern-Related Visual Stress More Apparent, Jana Wegrzyn

Student Theses, Dissertations and Capstones

Pattern-related visual stress (PRVS) refers to the perceptual difficulties experienced by some individuals when exposed to high contrast striped patterns. People with PRVS were reported to have reduced sensitivity to global motion at baseline testing and the difference disappears at a second estimate. The present study was to investigate the effect of practice on global motion threshold in adults with and without PRVS. Methods: A total of 101 subjects were recruited and the Wilkins & Evans Pattern Glare Test was used to determine if a subject had PRVS. The threshold to detect global motion was measured with a random dot …

Biological Port Sampling Software (Biosamp) Development, Joshua Moser

M. S. in Project Management

The Northeast Port Biological Sampling Program collects marine organism lengths, length frequencies and age structures (otoliths, scales, spines, etc...) which are strategically requested to attain a representative sample of the associated federally managed stocks. Historically the biological sampling staff have used paper based data collection methods in the field and then transcribed this data into a web based data entry application. These methods are prone to error in legibility, transcription and data entry; an electronic data collection process will significantly reduce the quantity of errors, improve the efficiency of data collection activities and increase data quality.

The Biological Port Sampling …

Handoff Communication Among Senior Nursing Students: A Phenomenological Study, Juanita Hanley-Gumbs

Student Theses, Dissertations and Capstones

Despite discussions in health care regarding poor communication and its link to patient safety, it was revealed in the literature that many student nurses are inadequately prepared to conduct handoff communication. Student nurses have difficulty in this area due to limited or no experience with the handoff process, which jeopardizes patient safety. The purpose of this research study was to understand how senior nursing students make meaning of their lived experiences with handoff communication. The guiding research question for this study is: How do senior nursing students make meaning of their lived experiences with handoff communication during the change-of-shift report …