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Researchers Discover New Biomarker For Age-Related Macular Degeneration, Staff

Browse All News

No abstract provided.

Too Hot To Move: Temperatures During Transportation Might Reduce The Survival Of Salvinia Weevils (Coleoptera: Curculionidae), Lauren A. Cozad, Rodrigo Diaz, Christopher R. Mudge

Faculty Publications

© 2019 Florida Entomological Society. All rights reserved. The biological control agent, Cyrtobagous salviniae Calder and Sands (Coleoptera: Curculionidae) (salvinia weevil), is being used for management of the highly invasive fern Salvinia molesta Mitchell (Salvinaceae) in Louisiana and Texas, USA. The weevils and plants are transported from the nurseries and rearing facilities to the field release sites in plastic totes. Despite the increased transport of weevil-infested plants during the warmer months, limited data exist on the impact of heat stress and survivability of adult C. salviniae. Therefore, research was conducted to determine temperatures inside totes during summer transport, and to …

Circular Rna Circnol10 Inhibits Lung Cancer Development By Promoting Sclm1-Mediated Transcriptional Regulation Of The Humanin Polypeptide Family, Aruo Nan, Lijian Chen, Nan Zhang, Yangyang Jia, Xin Li, Hanyu Zhou, Yihui Ling, Zhishan Wang, Chengfeng Yang, Sijin Liu, Yiguo Jiang

Toxicology and Cancer Biology Faculty Publications

circNOL10 is a circular RNA expressed at low levels in lung cancer, though its functions in lung cancer remain unknown. Here, the function and molecular mechanism of circNOL10 in lung cancer development are investigated using in vitro and in vivo studies, and it is shown that circNOL10 significantly inhibits the development of lung cancer and that circNOL10 expression is co‐regulated by methylation of its parental gene Pre‐NOL10 and by splicing factor epithelial splicing regulatory protein 1 (ESRP1). circNOL10 promotes the expression of transcription factor sex comb on midleg‐like 1 (SCML1) by inhibiting transcription factor ubiquitination and thus also affects regulation …

Cerebrovascular Smooth Muscle Cells As The Drivers Of Intramural Periarterial Drainage Of The Brain, Roxana Aldea, Roy O. Weller, Donna M. Wilcock, Roxana O Carare, Giles Richardson

Physiology Faculty Publications

The human brain is the organ with the highest metabolic activity but it lacks a traditional lymphatic system responsible for clearing waste products. We have demonstrated that the basement membranes of cerebral capillaries and arteries represent the lymphatic pathways of the brain along which intramural periarterial drainage (IPAD) of soluble metabolites occurs. Failure of IPAD could explain the vascular deposition of the amyloid-beta protein as cerebral amyloid angiopathy (CAA), which is a key pathological feature of Alzheimer's disease. The underlying mechanisms of IPAD, including its motive force, have not been clarified, delaying successful therapies for CAA. Although arterial pulsations from …

Unh Manchester Launches Program To Boost State’S Biosciences Workforce, Erika Mantz

UNH Today Archive

No abstract provided.

Templating The Formation Of Multidimensional Hybrid Materials And Composites, Garrett Kraft

Doctoral Dissertations

Templating is a commercially viable process to achieve materials with reproducible morphology ranging from the nano-scale to the macro-scale. Templating techniques can be broken down into two broad categories based on their design strategy. The two design strategies are ether sacrificial templates or reusable templates. Sacrificial templates are consumed or unrecoverable. As a result, a new template has to be made and used with every production run and must be inexpensive to keep manufacturing costs reasonable. A reusable template requires that the template be durable and easily removed from the material afterward without damaging the structure that was just templated. …

Stride-Time Variability Is Related To Sensorimotor Cortical Activation During Forward And Backward Walking, Boman Groff, Prokopios Antonellis, Kendra K. Schmid, Brian Knarr, Nicholas Stergiou

Journal Articles

Previous research has used functional near-infrared spectroscopy (fNIRS) to show that motor areas of the cortex are activated more while walking backward compared to walking forward. It is also known that head movement creates motion artifacts in fNIRS data. The aim of this study was to investigate cortical activation during forward and backward walking, while also measuring head movement. We hypothesized that greater activation in motor areas while walking backward would be concurrent with increased head movement. Participants performed forward and backward walking on a treadmill. Participants wore motion capture markers on their head to quantify head movement and pressure …

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.

Time Keeping: Philippine Style, S.J. Badillo

Philippine Studies: Historical and Ethnographic Viewpoints

No abstract provided.

Spectator 2019-01-23, Editors Of The Spectator

The Spectator

No abstract provided.

Scientometric Study On Immunology At National Level Through Web Of Science Database, Sathiyapriya Sathiyapriya.C, Gomathi Palanisamy

Library Philosophy and Practice (e-journal)

Abstract

This study reveals that research productivity of Immunology in India during the year 1993-2017 (25 years). The Web of Science (WoS) database was used in the data reclamation. The explore term used was “Immunology” and considered as a vital keyword of the topic discussed. Source and highly cited articles based on data obtained on Immunology beginning Web of Knowledge. It is found that the Country is India together contributed 397 articles during 1993-2017. The study mainly focused that year wise, Language wise publications, Document type publications, Authorship pattern, Subramaniam’s degree of collaboration and H- index score for highly productive …

Nature On The Move, Onno Oerlemans

Criticism

No abstract provided.

The Divergence Of Binary Sex And The Transgender, Kelsey Marie Pittman

Liberty University Law Review

No abstract provided.

The Absence Of Religious Neutrality In K-12 Public Science Education, John H. Calvert

Liberty University Law Review

No abstract provided.

Materials Deemed Harmful To Minors Are Welcomed Into Classrooms And Libraries Via Educational "Obscenity Exemptions", Judith A. Reisman, Mary E. Mcalister

Liberty University Law Review

No abstract provided.

Academic Senate - Agenda, 1/22/2019, Academic Senate

Academic Senate Agendas

No abstract provided.

The Lumberjack Newspaper, January 22, 2019, The Lumberjack Staff

2019

The student newspaper of Humboldt State University

Integrating Wildfires Propagation Prediction Into Early Warning Of Electrical Transmission Line Outages, Songyi Dian, Peng Cheng, Qiang Ye, Jirong Wu, Ruisen Luo, Chen Wang, Dafeng Hui, Ning Zhou, Dong Zou, Qin Yu, Xiaofeng Gong

Biology Faculty Research

Wildfires could pose a significant danger to electrical transmission lines and cause considerable losses to the power grids and residents nearby. Previous studies of preventing wildfire damages to electrical transmission lines mostly analyze wildfire and power system security independently due to their differences in disciplines and cannot satisfy the requirement of the power grid for active and timely responses. In this paper, we have designed an integrated wildfire early warning system framework for power grids, taking prediction of wildfires and early warning of line outage probability together. First, the proposed model simulates the spatiotemporal process of wildfires via a geography …

Putative Cellular And Molecular Roles Of Zika Virus In Fetal And Pediatric Neuropathologies, Rajendra Ghardbaran, Rajendra Ghardbaran, Latchman Somenarain

Publications and Research

Although the World Health Organization declared an end to the recent Zika virus (ZIKV) outbreak and its association with adverse fetal and pediatric outcome, on November 18, 2016, the virus still remains a severe public health threat. Laboratory experiments thus far supported the suspicions that ZIKV is a teratogenic agent. Evidence indicated that ZIKV infection cripples the host cells' innate immune responses, allowing productive replication and potential dissemination of the virus. In addition, studies suggest potential transplacental passage of the virus and subsequent selective targeting of neural progenitor cells (NPCs). Depletion of NPCs by ZIKV is associated with restricted brain …

Scholar Tackles Slimy Project To Improve Gwu Environmental Sustainability Practices, Office Of University Communications

Gardner-Webb NewsCenter Archive

For his summer research project, one Gardner-Webb University senior enthusiastically tackled a dirty and slimy process. Jacob C. Jackson ’19 chose a socially-responsible research project for the immediate impact it would have on campus waste management. The biology major from Tryon, N.C., decided to expand the work done by a previous undergraduate scholar to improve the University’s environmental sustainability practices.

Cytochrome P450s And Uses Thereof, Joseph Chappell, Lyle F. Ralston

Pharmaceutical Sciences Faculty Patents

The invention relates to isolated cytochrome P450 polypeptides and nucleic acid molecules, as well as expression vectors and transgenic plants containing these molecules. In addition, the invention relates to uses of such molecules in methods of increasing the level of resistance against a disease caused by a plant pathogen in a transgenic plant, in methods for producing altered compounds, for example, hydroxylated compounds, and in methods of producing isoprenoid compounds.

Multi-Ancestry Study Of Blood Lipid Levels Identifies Four Loci Interacting With Physical Activity, Tuomas O. Kilpeläinen, Amy R. Bentley, Raymond Noordam, Yun Ju Sung, Karen Schwander, Thomas W. Winkler, Hermina Jakupović, Daniel I. Chasman, Alisa Manning, Ioanna Ntalla, Hugues Aschard, Michael R. Brown, Lisa De Las Fuentes, Nora Franceschini, Xiuqing Guo, Dina Vojinovic, Stella Aslibekyan, Mary F. Feitosa, Minjung Kho, Solomon K. Musani, Melissa Richard, Heming Wang, Zhe Wang, Traci M. Bartz, Lawrence F. Bielak, Archie Campbell, Rajkumar Dorajoo, Virginia Fisher, Fernando P. Hartwig, Andrea R. V. R. Horimoto, Donna K. Arnett

Epidemiology and Environmental Health Faculty Publications

Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects. To identify lipid loci interacting with physical activity, we performed genome-wide analyses of circulating HDL cholesterol, LDL cholesterol, and triglyceride levels in up to 120,979 individuals of European, African, Asian, Hispanic, and Brazilian ancestry, with follow-up of suggestive associations in an additional 131,012 individuals. We find four loci, in/near CLASP1, LHX1, SNTA1, and CNTNAP2, that are associated with circulating lipid levels through interaction with physical activity; higher levels of physical activity enhance the HDL …

Gene Annotation Errors Are Common In The Mammalian Mitochondrial Genomes Database., Carlos F Prada, Jeffrey L Boore

Articles, Abstracts, and Reports

BACKGROUND: Although animal mitochondrial DNA sequences are known to evolve rapidly, their gene arrangements often remain unchanged over long periods of evolutionary time. Therefore, comparisons of mitochondrial genomes may result in significant insights into the evolution both of organisms and of genomes. Mammalian mitochondrial genomes recently published in the GenBank database of NCBI show numerous rearrangements in various regions of the genome, from which it may be inferred that the mammalian mitochondrial genome is more dynamic than expected. However, it is alternatively possible that these are errors of annotation and, if so, are misleading our interpretations. In order to verify …

New Master's Degree In Anatomy Offered, And Classes Begin In June, Staff

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No abstract provided.

Biotransformed Metabolites Of The Hop Prenylflavanone Isoxanthohumol, Hyun Jung Kim, Soon-Ho Yim, Fubo Han, Bok Yun Kang, Hyun Jin Choi, Da-Woon Jung, Darren R. Williams, Kirk R. Gustafson, Edward J. Kennelly, Ik-Soo Lee

Publications and Research

A metabolic conversion study on microbes is known as one of the most useful tools to predict the xenobiotic metabolism of organic compounds in mammalian systems. The microbial biotransformation of isoxanthohumol (1), a major hop prenylflavanone in beer, has resulted in the production of three diastereomeric pairs of oxygenated metabolites (2–7). The microbial metabolites of 1 were formed by epoxidation or hydroxylation of the prenyl group, and HPLC, NMR, and CD analyses revealed that all of the products were diastereomeric pairs composed of (2S)- and (2R)- isomers. The structures of these metabolic compounds were elucidated to be (2S,200S)- and (2R,200S)-40 …

Assessing Insect Flight Behavior In The Laboratory: A Primer On Flight Mill Methodology And What Can Be Learned, Steven E. Naranjo

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Dispersal is a key component in the population ecology and dynamics of insects and remains one of the most difficult and intractable ecological processes to study in the field. As a consequence, many researchers have looked to laboratory methods for investigating the myriad factors that govern and impact an insect’s ability to move within its environment. A key tool in this effort since at least the early 1950s has been the insect flight mill. Nearly 260 studies have been published using flight mills covering 214 species in 61 families and 9 orders. This review explores the methodology and technology of …

Cytochrome P450s And Uses Thereof, Joseph Chappell, Lyle F. Ralston

Pharmaceutical Sciences Faculty Patents

The invention relates to isolated cytochrome P450 polypeptides and nucleic acid molecules, as well as expression vectors and transgenic plants containing these molecules. In addition, the invention relates to uses of such molecules in methods of increasing the level of resistance against a disease caused by a plant pathogen in a transgenic plant, in methods for producing altered compounds, for example, hydroxylated compounds, and in methods of producing isoprenoid compounds.

Crow's Nest, January 22, 2019, Crow's Nest Staff

Crow's Nest

The January 22, 2019, issue of the Crow's Nest.

The Daily Gamecock, Tuesday, January 22, 2019, University Of South Carolina, Office Of Student Media

January

No abstract provided.

Upregulation Of The Wnk4 Signaling Pathway Inhibits Epithelial Sodium Channels Of Mouse Tracheal Epithelial Cells After Influenza A Infection, Yapeng Hou, Yong Cui, Zhiyu Zhou, Hongfei Liu, Hongfei Zhang, Yan Ding, Hongguang Nie, Hong-Long Ji

Cellular and Molecular Biology Faculty Publications and Presentations

Influenza virus has a significant impact on the respiratory system. The mechanism of how influenza virus impairs the fluid transport in airway is not fully understood. We examined its effects on epithelial sodium channels (ENaC), which are very important for water and salt transport in the respiratory system. We focused on the impacts of influenza virus on ENaC activity in mouse tracheal epithelial cells (MTECs) and applied Ussing chamber apparatus for recording the short-circuit currents in primary cultured MTECs. Expressions of α and γ-ENaC were measured at the protein and mRNA levels by western blot and quantitative real-time polymerase chain …