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2019

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Exploring Convergence Of Snake Skin-Inspired Texture Designs And Additive Manufacturing For Mechanical Traction, Catherine Sue Tiner Dec 2019

Exploring Convergence Of Snake Skin-Inspired Texture Designs And Additive Manufacturing For Mechanical Traction, Catherine Sue Tiner

Graduate Theses and Dissertations

This research focuses on the understanding, development, and additive manufacture of a 3D printed snake skin-inspired texture pattern. The design functionalities of snake skin were determined through the study of the snake species Python Regius otherwise known as the ball python. Each scale of a snake has hierarchical texture with hexagonal macro-patterns aligned on the ventral surface of the skin with overriding anisotropic micro textured patterns such as denticulations and fibrils. Using a laser-powder bed fusion (L-PBF) process, 420 stainless steel samples were 3D printed which closely resemble the above described directional texture of natural snake skin. This printed surface …


Asymmetric Synthesis Of The C29-C34 Moiety Of Fragment A Of The Antascomicin B & Thermal Azole Based Claisen Rearrangements, Dharma Theja Nannapaneni Dec 2019

Asymmetric Synthesis Of The C29-C34 Moiety Of Fragment A Of The Antascomicin B & Thermal Azole Based Claisen Rearrangements, Dharma Theja Nannapaneni

Graduate Theses and Dissertations

The dissertation describes asymmetric synthesis towards C29-C34 moiety of fragment A of the Antascomicin B and Thermal azole based Claisen rearrangements. In chapter 1, we describes asymmetric synthesis towards C29-C34 moiety of fragment A of the Antascomicin B. The non-immunosuppressant Rapamycin, Ascomycin, and Tacrolimus (FK506), strongly binds with FKBP12, the ligand FKBP12 complexes responsible for immunosuppressive activity. Antascomicin B structurally related to Rapamycin, Ascomycin, and Tacrolimus (FK506), binds strongly to FKBP12, yet does not shown immunosuppressive activity. The ligand FKBP12 binding complexes shown to have potent neuroprotective and neurogenerative properties in mouse models of Parkinson’s disease. The linear synthesis of …


Coccidiosis Vaccination And Nutrient Utilization In Broiler Chickens, Alyson Elaine Gautier Dec 2019

Coccidiosis Vaccination And Nutrient Utilization In Broiler Chickens, Alyson Elaine Gautier

Graduate Theses and Dissertations

Four experiments were conducted to evaluate the interrelationships among coccidiosis vaccination and nutrient utilization in floor-reared broiler chickens. Experiment 1 longitudinally compared the effects of coccidiosis vaccination and a chemical coccidiostat on broiler performance, nutrient digestibility, and intestinal morphology. Coccidiosis vaccination had no significant impact on morphology, overall body weight gain and feed intake of vaccinated birds, although vaccination impaired overall FCR. Vaccination elicited a transient reduction in digestibility of energy and nutrients, particularly for lipids, but vaccinated birds were able to recover from these reductions by 20 d. Experiment 2 assessed the impact of vaccination in digestibility of different …


Quantitative Analysis Techniques For Assessing Organelle Organization And Dynamics In Individual Cells, Isaac Vargas Dec 2019

Quantitative Analysis Techniques For Assessing Organelle Organization And Dynamics In Individual Cells, Isaac Vargas

Graduate Theses and Dissertations

In biomedical optics and microscopy, the organization and morphology of organelles have been widely studied. In spite of novel imaging techniques, there is still a lack of quantitative tools to easily measure cellular characteristics from image data. Previous studies have explored multiple approaches to assess organelle organization and alignment, resulting in complicated and extensive algorithms that are both subject to multiple steps of image processing and influenced by non-cellular artifacts. In this thesis, a technique called the Modified Blanket Method (MBM) is introduced to quantify organelle organization through measurements of fractal dimension (FD) on a pixel-by-pixel basis. With the use …


Early Recruitment Of Crassostrea Virginica To Restored And Natural Oyster Reefs In The Western Mississippi Sound: Larval Supply And Post-Settlement Success, Leah Morgan Dec 2019

Early Recruitment Of Crassostrea Virginica To Restored And Natural Oyster Reefs In The Western Mississippi Sound: Larval Supply And Post-Settlement Success, Leah Morgan

Master's Theses

The eastern oyster (C. virginica) is a foundation species that improves water quality, protects shorelines, provides refuge for other organisms, and contributes to commercial fisheries. Successful early recruitment of eastern oyster is vital for resupplying adult populations in the face of habitat loss. Coastal oyster populations are challenged by freshwater input, hypoxia, predation and overfishing. Consequently, substantial efforts have been dedicated toward oyster restoration within the northern Gulf of Mexico. The overall objective of this study was to consider the role and importance of early recruitment to oyster restoration in western Mississippi Sound. During the summer 2018 recruitment period, we …


Distribution, Abundance, And Trophic Ecology Of Anguilliform Leptocephali In The Northern Gulf Of Mexico, Lillian Collins Dec 2019

Distribution, Abundance, And Trophic Ecology Of Anguilliform Leptocephali In The Northern Gulf Of Mexico, Lillian Collins

Master's Theses

All species of anguilliform eels have pelagic leptocephalus larval stages, which provides a means of monitoring the population dynamics of these otherwise cryptic and hard to study species. The goals of this study were to: 1) describe the distribution and abundance of anguilliform eel leptocephali across the northern Gulf of Mexico, and 2) examine the trophic ecology of leptocephali using stable isotope values of carbon and nitrogen (δ13C and δ15N). A 25-year (1990-2014) ichthyoplankton dataset provided by the National Oceanic and Atmospheric Administration (NOAA) Southeast Area Monitoring and Assessment Program (SEAMAP) was used to examine interannual variations in leptocephalus distribution, …


Development And Employment Of Environmental Dna Methods For The Detection Of Bull Sharks (Carcharhinus Leucas) In A Freshwater And Estuarine Interface In The Mobile-Tensaw Delta And Mobile Bay, Alabama, Katherine Schweiss Dec 2019

Development And Employment Of Environmental Dna Methods For The Detection Of Bull Sharks (Carcharhinus Leucas) In A Freshwater And Estuarine Interface In The Mobile-Tensaw Delta And Mobile Bay, Alabama, Katherine Schweiss

Master's Theses

Species conservation and management is influenced by the quality of monitoring methods employed, especially when targeting elusive, but ecologically significant species, like elasmobranchs. Bull Sharks (Carcharhinus leucas) are highly mobile predators that rely on estuaries and freshwater rivers for maturation, resources, and refuge; their ability to withstand changing environmental conditions may mean they are linking ecosystems through their habitat usage and movements. Rather than setting nets or attaching acoustic monitoring devices, which can be expensive, time-consuming, and invasive, the analysis of environmental DNA (eDNA) for tracing species presence was used to target C. leucasDNA. The present research …


Effects Of Water Table Depth And Edaphic Characteristics On Plant Diversity In A Southern Mississippi Pitcher Plant Bog, Patrick Kirby Dec 2019

Effects Of Water Table Depth And Edaphic Characteristics On Plant Diversity In A Southern Mississippi Pitcher Plant Bog, Patrick Kirby

Master's Theses

This study examined the effects that water table depth and soil characteristics have on plant species richness and species composition within pitcher plant bogs across seasons. Eight piezometers were installed at random distances to monitor long-term water table depth and pressure fluctuations along a ~710-meter line transect traversing upland and bog habitats. Vegetation sampling quadrats (n=128) were set up near each piezometer. Cover data and water table depths were collected in spring and late summer. Soil samples collected from each treatment group were used to obtain soil texture and nutrient data. The summer collection period yielded a total gdiversity of …


Estimating Body Mass Through Bone Mineral Density Studies Using Dexa (Dual-Energy X-Ray Absorptiometry), Kaitlin Harstine Dec 2019

Estimating Body Mass Through Bone Mineral Density Studies Using Dexa (Dual-Energy X-Ray Absorptiometry), Kaitlin Harstine

Master's Theses

Identification of a decedent is one of the primary goals of forensic anthropologists. In order to do this, one must build a biological profile based on the remains that are provided. Sex, age, ancestry, and stature are four of the most common, however a fifth addition piece of information that could be beneficial is body mass. The goal of this research is to explore the relationship between bone mineral density (BMD) and body mass, using data collected from dual x-ray absorptiometry (DEXA) scans of 107 collegiate football athletes. Athletes are a good fit for this study because they have achieved …


The Effect Of Historic Shipwrecks On Sediment Microbiomes In The Northern Gulf Of Mexico, Melissa Brock Dec 2019

The Effect Of Historic Shipwrecks On Sediment Microbiomes In The Northern Gulf Of Mexico, Melissa Brock

Master's Theses

Microorganisms are ubiquitously distributed across all aquatic habitats, but it is the environmental conditions of a habitat that determine which microorganisms can thrive in terms of abundance or metabolic activity. Habitats that experience consistent physical and chemical environmental conditions repeatedly favor specific taxonomic groups which may result in a microbial assemblage that is commonly associated with that habitat (i.e., a core microbiome). Core microbiomes have been identified for a variety of natural marine habitats including methane seeps, wood falls, octocoral, and deep-sea sediments. However, it was unknown if the presence of man-made structures on the seafloor, including historic shipwrecks, also …


Elevated Adhd Symptoms As A Predictor Of Rule Violations Among Male Juvenile Offenders, Kathleen Lolley Ramsey Dec 2019

Elevated Adhd Symptoms As A Predictor Of Rule Violations Among Male Juvenile Offenders, Kathleen Lolley Ramsey

Master's Theses

Youth with ADHD are disproportionately at-risk for engaging in criminality and aggression relative to the general population, and this may be a function of underlying executive function deficits associated with self-regulation. More specifically, youth with ADHD may be susceptible to difficulties with behavioral regulation (impulsivity) and emotional regulation (e.g., managing feelings of anger). The current study sought to expand on previous research to examine the relationship between ADHD symptoms and aggression and the potential moderating effects of anger control among institutionalized youth. Archival data comprising a sample (N=119) of male adolescents who were admitted to a maximum-security residential facility were …


Involuntary Signal-Based Grounding Of Civilian Unmanned Aerial Systems (Uas) In Civilian Airspace, Keith Conley Dec 2019

Involuntary Signal-Based Grounding Of Civilian Unmanned Aerial Systems (Uas) In Civilian Airspace, Keith Conley

Master's Theses

This thesis investigates the involuntary signal-based grounding of civilian unmanned aerial systems (UAS) in unauthorized air spaces. The technique proposed here will forcibly land unauthorized UAS in a given area in such a way that the UAS will not be harmed, and the pilot cannot stop the landing. The technique will not involuntarily ground authorized drones which will be determined prior to the landing. Unauthorized airspaces include military bases, university campuses, areas affected by a natural disaster, and stadiums for public events. This thesis proposes an early prototype of a hardware-based signal based involuntary grounding technique to handle the problem …


Expanding The Fear Of Loss Of Vigilance Theory: Using Intolerance Of Uncertainty, Responsibility For Harm, And Fear Of Sleep To Predict Nocturnal Panic Attacks, Nicole S. Smith Dec 2019

Expanding The Fear Of Loss Of Vigilance Theory: Using Intolerance Of Uncertainty, Responsibility For Harm, And Fear Of Sleep To Predict Nocturnal Panic Attacks, Nicole S. Smith

Master's Theses

Nocturnal panic involves experiencing panic attacks out of a sleeping state without obvious causes such as nightmares or loud noises. Roughly half of patients with panic disorder will experience nocturnal panic in addition to panic attacks while awake, or daytime panic. Like daytime panic, nocturnal panic also occurs in other disorders such as PTSD. The Fear of Loss of Vigilance theory is currently the only model available to explain nocturnal panic. It suggests that nocturnal panickers fear states in which they cannot easily react to or protect themselves from danger. Prior research using a self-report measure to differentiate nocturnal and …


The Thiol Specific Antioxidant (Tsa1) Gene Is Required For Survival In Macrophages And Oxidative Stress Resistance In Histoplasma Capsulatum, Lauren Kennedy Dec 2019

The Thiol Specific Antioxidant (Tsa1) Gene Is Required For Survival In Macrophages And Oxidative Stress Resistance In Histoplasma Capsulatum, Lauren Kennedy

Master's Theses

Histoplasma capsulatum(Hc) is a pathogenic fungus that causes one of the most common invasive fungal respiratory diseases, Histoplasmosis. Histoplasmaundergoes a dimorphic shift from mold to yeast which is crucial to pathogenesis of the organism.

The thiol specific antioxidant gene, Tsa1,is strongly upregulated in the yeast (pathogenic) morphotype. This data led to the hypothesis that this gene plays a role in protecting Hcfrom host mediated oxidative attack. To characterize Tsa1 function, a knockdown strain (tsa1-RNAi) was created by RNAi gene silencing. Expression of Tsa1in the tsa1-RNAistrain was reduced to 10% that …


The Variability Of High-Frequency Motions And Their Interactions With The Mesoscale On The Mississippi Shelf, Jordan Earls Dec 2019

The Variability Of High-Frequency Motions And Their Interactions With The Mesoscale On The Mississippi Shelf, Jordan Earls

Master's Theses

In this study, we examine the spatial and temporal variability of high-frequency and low-frequency motions across the Mississippi Shelf and how the high-frequency motions are modulated by low-frequency mesoscale motions. For this purpose, we use Acoustic Doppler Current Profiler (ADCP) measurements collected at nearshore (23 m), mid-shelf (60 m), and shelf break (88 m) stations. High-frequency motions are defined as motions with periods less than 36 hours, whereas mesoscale motions have larger periods. The collected datasets are analyzed through bandpass filtering, least square harmonic analysis, spectral analysis, and empirical orthogonal functions (EOF). We find that along-shelf barotropic mesoscale motions contain …


The Quiet Classroom Game With An Indiscriminable Contingency In A High School, Stefanie Schrieber Dec 2019

The Quiet Classroom Game With An Indiscriminable Contingency In A High School, Stefanie Schrieber

Master's Theses

The Quiet Classroom Game (QCG) is an interdependent group contingency utilized to decrease classroom noise levels, increase student engagement, and decrease disruptive behaviors in the classroom setting. The purpose of the current study was to investigate the effects of the QCG in three high school classrooms in the Southeastern United States. Classrooms were recruited based on teacher reports of excessive noise and high rates of disruptive behavior. A multiple baseline design with two intervention phases was utilized to examine the effects of the intervention. The first phase was the QCG alone, and the second phase was the QCG with an …


Changes In Antarctic Bottom Water Formation During Interglacial Periods, Samuel Glasscock Dec 2019

Changes In Antarctic Bottom Water Formation During Interglacial Periods, Samuel Glasscock

Master's Theses

In the modern Southern Ocean and during the last interglacial period, Marine Isotope Stage 5, there are observations that point to reduced Antarctic Bottom Water (AABW) formation. These reductions are believed to be driven by an increase in the strength of the Southern Ocean density stratification due to surface water freshening. Any reduction in AABW formation has important implications for global climate as AABW plays a vital role in the cycling of carbon in the world’s ocean. The primary question this study seeks to answer is do these AABW reductions occur during any of the other interglacials of the past …


Novel Optimization Approaches For Integrated Design And Operation Of Smart Manufacturing And Energy Systems, Alphonse Hakizimana Dec 2019

Novel Optimization Approaches For Integrated Design And Operation Of Smart Manufacturing And Energy Systems, Alphonse Hakizimana

All Dissertations

This dissertation contributes novel theoretical results that enable the use of efficient optimization algorithms for the design of energy and manufacturing systems with high operational flexibility. Operational flexibility is a central theme of the smart grid and smart manufacturing paradigms because it enables systems to optimally adapt to highly dynamic and uncertain operating environments. Such environments are increasingly prevalent in the energy and manufacturing industries due to factors such as the increasing use of variable renewable energy resources (e.g., wind and solar) and the potential benefits of responding quickly to variations in product demands, real-time electricity markets, etc. For systems …


African American Female Law Enforcement Officers' Lived Experiences And Mentoring: A Thematic Narrative, Harold Wilson Dec 2019

African American Female Law Enforcement Officers' Lived Experiences And Mentoring: A Thematic Narrative, Harold Wilson

Doctoral Dissertations

Black female officers are an underrepresented sub-group of the law-enforcement profession. The bulk of research on women’s policing has focused on the growth of women in law enforcement, barriers, sexual harassment, gender differences, why women are deterred from law enforcement, physical limitations, and instruments used during the recruitment process, and the stress endured after entry into the profession. When looking at Black female officers’ lived experience and perceptions around mentoring; research is lacking. Eight Black female officers from the San Francisco Bay Area participated in this study. Findings revealed that all of the women have faced a recurring sense of …


Community Leader-Scholars With Refugee Experiences: Collective Hope, Healing, And Multi-Generational Resistance, Jane Pak Dec 2019

Community Leader-Scholars With Refugee Experiences: Collective Hope, Healing, And Multi-Generational Resistance, Jane Pak

Doctoral Dissertations

Through a Critical Refugee Studies (CRS) lens that inherently challenges power, encourages multi-disciplinary approaches, and centers refugee epistemologies, this study centers ways of knowing and being among a group of ten Community Leader-Scholars (CoLS) with refugee experiences. This dissertation posits that CoLS offer critical perspectives that introduce new logics that disrupt traditional spaces and power dynamics. I frame CoLS as undergraduate or graduate students (or recent alumni) with refugee experiences who have self-identified and illustrated a commitment to community well-being in one or more of their transnational communities. This study employed qualitative research methods that included 10 interviews and four …


Caesarean Section Rates In South Asian Cities: Can Midwifery Help Stem The Rise?, Sulochana Dhakal Rai, Amudha Poobalan, Rafat Jan, Malin Bogren, Juliet Wood, Ganesh Dangal, Pramod Regmi, Edwin Van Teijlingen, Keshar Bahadur Dhakal, Sahib Jan Badar, Farhana Shahid Dec 2019

Caesarean Section Rates In South Asian Cities: Can Midwifery Help Stem The Rise?, Sulochana Dhakal Rai, Amudha Poobalan, Rafat Jan, Malin Bogren, Juliet Wood, Ganesh Dangal, Pramod Regmi, Edwin Van Teijlingen, Keshar Bahadur Dhakal, Sahib Jan Badar, Farhana Shahid

Journal of Asian Midwives (JAM)

Introduction: Caesarean section (CS) is a life-saving surgical intervention for delivering a baby when complications arisein childbirth. World Health Organization recommends a rate of CS from 10% to 15%. However, CS rates increased steadily in recent decades and have almost doubled from 12.1% in 2000 to 21.1% in 2015. Therefore, this has become a global public health problem. The main purpose of the scoping review article is to give an overview and analysis of the rising CS use in four South Asian countries: Bangladesh, India, Nepal and Pakistan.
Methods: A scoping review was carried-out using several bibliographic electronic databases (MEDLINE, …


Factors Related To Adverse Mental Health Condition Of Demented Family Caregivers: A Study In West Bengal, India, Ipsita Basu, Susmita Mukhopadhyay Dec 2019

Factors Related To Adverse Mental Health Condition Of Demented Family Caregivers: A Study In West Bengal, India, Ipsita Basu, Susmita Mukhopadhyay

Journal Articles

Dementia caregiving is a unique and the caregivers faces extreme challenges which affect care-giver's mental health adversely. Family caregiving towards elderly individuals with dementia is becoming widespread. The study aims to evaluate the mental health status of dementia family caregivers and some related factors that affect their mental health condition. Present cross sectional study includes a total of 134 family caregivers. Socio-demographic and caregiving related data were collected using pre-tested questionnaires. Standardized questionnaires were used to collect data on caregivers' mental health traits (measured in terms of level of stress and anxiety), level of psychosocial distress, support they provided and …


Bio-Chemical Assay Locking To Thwart Bio-Ip Theft, Sukanta Bhattacharjee, Jack Tang, Sudip Poddar, Mohamed Ibrahim, Ramesh Karri, Krishnendu Chakrabarty Dec 2019

Bio-Chemical Assay Locking To Thwart Bio-Ip Theft, Sukanta Bhattacharjee, Jack Tang, Sudip Poddar, Mohamed Ibrahim, Ramesh Karri, Krishnendu Chakrabarty

Journal Articles

It is expected that as digital microfluidic biochips (DMFBs) mature, the hardware design flow will begin to resemble the current practice in the semiconductor industry: design teams send chip layouts to third-party foundries for fabrication. These foundries are untrusted and threaten to steal valuable intellectual property (IP). In a DMFB, the IP consists of not only hardware layouts but also of the biochemical assays (bioassays) that are intended to be executed on-chip. DMFB designers therefore must defend these protocols against theft. We propose to “lock” biochemical assays by inserting dummy mix-split operations. We experimentally evaluate the proposed locking mechanism, and …


A Powerful Method To Integrate Genotype And Gene Expression Data For Dissecting The Genetic Architecture Of A Disease, Sarmistha Das, Partha Pratim Majumder, Raghunath Chatterjee, Aditya Chatterjee, Indranil Mukhopadhyay Dec 2019

A Powerful Method To Integrate Genotype And Gene Expression Data For Dissecting The Genetic Architecture Of A Disease, Sarmistha Das, Partha Pratim Majumder, Raghunath Chatterjee, Aditya Chatterjee, Indranil Mukhopadhyay

Journal Articles

To decipher the genetic architecture of human disease, various types of omics data are generated. Two common omics data are genotypes and gene expression. Often genotype data for a large number of individuals and gene expression data for a few individuals are generated due to biological and technical reasons, leading to unequal sample sizes for different omics data. Unavailability of standard statistical procedure for integrating such datasets motivates us to propose a two-step multi-locus association method using latent variables. Our method is powerful than single/separate omics data analysis and it unravels comprehensively deep-seated signals through a single statistical model. Extensive …


Occupational Health Hazards Of Library Professionals In India, Jiban K. Pal Dec 2019

Occupational Health Hazards Of Library Professionals In India, Jiban K. Pal

Journal Articles

The paper revisits a wide variety of health hazards in the library workplace. Through an exhaustive review, it explores the underlying causes of occupational risk & injuries to library workers; aiming to raise the awareness of healthy working practices and statutory requirements. It reflects the viewpoints surrounding the health and safety in libraries to illustrate possible health hazards of library workers in an Indian context. The paper informs about a variety of burdens that persist in the library workplace. It also outlines the major causes of occupational risk in terms of physical, chemical, biological, technological, emotional, and psychosocial hazards. It …


Arboretum Exchange, Fall 2019, Olivia Arias, Zinan Chi, Rudy Lawler, Emily Nelson, Ryan Rhee Dec 2019

Arboretum Exchange, Fall 2019, Olivia Arias, Zinan Chi, Rudy Lawler, Emily Nelson, Ryan Rhee

Sustainability Exchange Projects

The Arboretum Project, led by Professor Stan Braude of Biology, worked to certify the WashU campus as a Level II Arboretum. Students learned to identify and catalog trees, identified creative ways to engage the public with WU campus natural resources, and worked with Buildings & Grounds and the Office of Sustainability to plan for the future of tree initiatives on campus.


Smallmouth Bass Population Demographics In Missouri Ozark Streams And An Evaluation Of A Statewide 305-Mm Minimum Length Limit, Edward M. Sterling, Kylie B. Sterling, Quinton E. Phelps, Tyler D. Ham, Sara J. Tripp Dec 2019

Smallmouth Bass Population Demographics In Missouri Ozark Streams And An Evaluation Of A Statewide 305-Mm Minimum Length Limit, Edward M. Sterling, Kylie B. Sterling, Quinton E. Phelps, Tyler D. Ham, Sara J. Tripp

College of Natural and Applied Sciences

The Ozark streams of Missouri provide anglers with unique Smallmouth Bass Micropterus dolomieu fishing opportunities. To ensure the sustainability and potential of these fisheries, we sampled five streams in the Ozark highland ecoregion of southern Missouri via recreational angling methods. From our samples, we developed estimates of recruitment, growth, and mortality, and assessed current regulations for Smallmouth Bass. To accomplish these objectives, we aged otoliths from 75 legal (305-mm) fish on each stream. Back-calculated length-at-age estimates were formed for sublegal lengths, and were paired with electrofishing length distributions on each stream using an age-length key. These data were used to …


Savvy Women And Boundary Negotiations In Qing Fiction, Jessica Moyer Dec 2019

Savvy Women And Boundary Negotiations In Qing Fiction, Jessica Moyer

East Asian Languages & Cultures: Faculty Publications

This paper examines a particular character type in Qing vernacular short stories: clever women who test the definition of feminine virtue by acting admirably outside normal gender boundaries. These female protagonists argue, meddle in men's business, divert property from the patriline, and even lose their chastity - yet each of them is presented as unquestionably virtuous. The rhetorical approaches by which their male authors present them in a positive light illuminate the strategies available to men and women for thinking creatively about gender in Qing China.


Exploring Self-Determination And Recreational Sports Participation For Adolescents With Disabilities, Samantha K. Papp Dec 2019

Exploring Self-Determination And Recreational Sports Participation For Adolescents With Disabilities, Samantha K. Papp

Honors Theses

Self-determination is a vital skill for individuals with disabilities and provides significant benefits, such as more positive adult outcomes and greater quality of life. Recreational sports participation is another fundamental aspect of life for individuals with disabilities, as it leads to increased physical activity, enhanced self-esteem, and improved peer acceptance. Despite the well-researched benefits of both self-determination skills and recreational sports participation, a literature review revealed few studies that examined the relationship between self-determination and recreational sports participation for individuals, particularly adolescents, with disabilities. This mixed methods study was designed to fill this void, using questionnaires, interviews, and observations to …


Towards The Synthesis Of An Artificial Fluorescent Siderophore, Ashley Burns Dec 2019

Towards The Synthesis Of An Artificial Fluorescent Siderophore, Ashley Burns

Honors Theses

Siderophores are molecules capable of binding ferric ions with high affinity (Ka = 1052). This thesis outlines our attempts to synthesize an artificial siderophore, which incorporates a signaling group to help monitor the uptake of ferric ions. The artificial siderophore is a tripodal molecular receptor synthesized in a five-step procedure with a proposed final sixth step. Rhodamine 6G azide (95.0% yield) was formed from rhodamine 6G and the synthesis of 2-azidoethanamine was modified from the literature. The tripodal arm portion of the sensor was successfully synthesized by protecting the catechol of 2,3-dihydroxybenzaldehyde to form 3-formyl-1,2-phenylene dimethanesulfonate (98.8% yield). The reduction …