Regionalist Social Movements In Contemporary Chile: Production Of Space, Place, Territory, And Scale Through Collective Action, Miguel A. Contreras

Dissertations - ALL

In the last decade, the organization of several territorially based social movements in Chile has expressed a significant level of social discomfort about the political and economic system of the country. The central objective of this dissertation is to analyze how motivations, achievements, and failures of these movements have a dialectical relationship with the spatial features, specifically with the concepts place, territory and scale. Critical geography, political geography, and social movements’ studies provide the theoretical framework for the analysis, highlighting the significance of social movements as producers of collective knowledge. This research used a qualitative approach with a mix-methods design …

Snowstorms In Upstate New York: Synoptics, Spatial Modeling And Temporal Variability, Justin Joseph Hartnett

Dissertations - ALL

This dissertation examines the characteristics of snowstorms that affect Central New York, a subsection of the eastern Great Lakes region, in a series of chapters organized as journal articles. The first article develops a classification scheme to categorize snowstorms in Central New York from the 1985/86 season to the 2014/15 season. Twelve different snowstorm types were classified by their connection to the Great Lakes, the presence or absence of a synoptic low, or their area of cyclogenesis.

The second article uses the 2055 classified snowstorms to examine their relative contribution to seasonal snowfall totals. Although lake-effect snowstorms are the dominant …

Homology Over A Complete Intersection Ring Via The Generic Hypersurface, Eric Jeffrey Ottman

Dissertations - ALL

We study homological properties and constructions for modules over a complete intersection ring $Q/(f_1,\ldots,f_c)$ by way of the related generic hypersurface ring $Q[T_1,\ldots,T_c]/(f_1T_1+\cdots+f_cT_c)$. The advantage of this approach is that over a hypersurface ring, free resolutions are eventually 2-periodic, given by matrix factorizations, and are thus relatively easy to understand. We approach this relationship in two ways. First, we give a correspondence between the two rings in the graded setting, where existing results are insufficient for preserving graded structures. As an application, we use this correspondence to move a functor appearing in a theorem of Orlov to the generic hypersurface …

Detection And Inference In Gravitational Wave Astronomy, Steven Daniel Reyes

Dissertations - ALL

We explore the detection and astrophysical modeling of gravitational waves de- tected by the Advanced Laser Interferometer Gravitational wave Observatory (LIGO) and Virgo. We discuss the techniques used in the PyCBC search pipeline to discover the first gravitational wave detection GW150914, and estimate the statistical signifi- cance of GW150914, and the marginal trigger LVT151012. During Advanced LIGO’s first observing run there were no detections of mergers from binary neutron star and neutron star-black hole binaries. We use Bayesian inference to place upper limits on the rate of coalescence of these binaries. We use developments made in the PyCBC search pipeline …

Homeostatic Elastic States And The Stability Of Elastic Arteries, Xinyu Zhang

Dissertations - ALL

Vascular mechanics has undergone significant growth within the last 50 years owing to the rapid development of nonlinear continuum mechanics occurring roughly within the same period and motivated primarily by rubber materials. However, one important distinction of blood vessels, in contrast to typical engineering materials is that, through a variety of physiological mechanisms, they seek to maintain constant a preferred mechanical state (mechanical homeostasis) thereby exhibiting a remarkable mechanical stability in response to temporal evolution and alterations in blood pressure, vessel tethering forces and geometry and material properties. The mechanical state experienced by blood vessels plays a critical role in …

Tailor Made In India: Jaipur's Masters Of Cloth, Doctors Of Clothing, Alisa Weinstein

Dissertations - ALL

This dissertation is about Jaipur’s tailors, making custom-crafted clothing for individual customers in a rapidly changing and globally fashion-informed India. Indian-crafted clothing and textiles are a source of pride domestically and have long been used and admired throughout the world. So how is that India’s tailors, the people whose knowledge, abilities, and hard work form the backbone of this industry, receive so little thought or recognition? Although tailors are a seemingly well-respected and integral part of shaping Jaipur’s cultural landscape, my inquiries often revealed that tailors and their labor are popularly characterized as mundane. While considerable attention gets paid to …

Raising An Indoor Generation: Outdoor Environmental Education Impact On Adolescent Development, Daisy Elizabeth Bewley

Student Theses 2015-Present

In an increasingly digital world, children are growing up with less involvement and interaction with the environment. Hands-on and experiential learning is less popular in schools and a more test-oriented and numerical evaluation is increasingly popular. This thesis explores the decrease in outdoor environmental education and the impact that has on adolescent development and developmental milestones in children. This impact extends past just mental development and impacts the physical health development of children. Obesity, attention deficit disorders, and other behavioral issues are just a few of the signs of the problems that have arisen due to a decrease in environmental …

Designing The City, Sustainably: Sustainability And Climate Change Resiliency In New York City, Cosima Balletti-Thomas

Student Theses 2015-Present

Abstract

This paper explores how New York City and especially Manhattan has integrated sustainability into its agenda as a coastal metropolitan nucleus. Secondly, it assesses the New York City’s resiliency strategies that utilize environmental policy and design to confront its vulnerability to changes in the environment on account of global climate change, which has primarily manifested in the Northeastern region in the form of sea level rise, storm surge, and frequent flooding. Chapter 1 uses quantitative climate data from a multitude of sources such as the New York State Department of Environmental Conservation'sreport on the “Impacts of Climate Change …

Preparing For Climate Change In New York City - Geographic Information Systems As A Valuable Tool For Natural Hazard Management, Amy Carrillo

Student Theses 2015-Present

This paper addresses the impact of climate change in New York City. Chapter 1 focuses on details found in the United Nations Intergovernmental Panel on Climate Change Report on the impact of climate change worldwide. At the city level, this paper analyzes New York City’s Risk Landscape: A Guide to Hazard Mitigation and New York City Panel on Climate Change 2019 Report, which provides data on how climate change will impact NYC, specifically. Chapter 2 explores the history of Geographic Information Systems (GIS) and its use in mitigation and conservation practices over time. Chapter 3 studies how GIS has been …

Engineering Hyaluronic Acid For Biomedical Applications, Deep S. Bhattacharya

Theses & Dissertations

This work presents research using the naturally available non- sulfated carbohydrate glycosaminoglycan hyaluronic acid (HA) for the synthesis of different chemical derivatives of HA for evaluation of binding kinetics with CD44 and P- selectin proteins for applications in fluorescence image-guided surgery. Chemical derivatives of HA such as deacetylated HA (deHA), sulfated HA (sHA), and deacetylated and sulfated HA (s-deHA) were synthesized by modulating sulfating and deacetylating reagents to alter binding specificities to CD44. Modified HA derivatives and CD44 biophysical interactions were assessed by fluorescence polarization. In silico techniques were also used to determine binding using molecular docking and MM-PBSA approaches. …

Efficacy And Efficiency Evaluation Of Real-Time Feedback For Caregiver Training, Elizabeth J. Preas

Theses & Dissertations

Children with an autism spectrum disorder often have deficits in completing activities of daily living skills independently, which then falls on the responsibility of caregivers to assist their child. Behavioral skills training is an efficacious method to train caregivers to implement various behavioral interventions that includes several training components, which can be time intensive. Alternative caregiver training methods that are effective and efficient are needed to train caregivers to implement activities of daily living skills with their child. The present study used two concurrent multiple-baseline across participants design to evaluate the effects of real-time feedback and behavioral skills training to …

Roles Of Autism Gene Arid1b In Murine Brain Development And Behavior, Amanda L. Smith

Theses & Dissertations

Autism spectrum disorder (ASD) and intellectual disability (ID) are highly prevalent neurodevelopmental disorders characterized by social and communication deficits, stereotyped behaviors, cognitive dysfunction, and deficits in adaptive behaviors. The pathogenesis underlying these disorders remains unknown, and thus no pharmacologic or genetic therapies are currently available. Recent progress in the field has shown that haploinsufficiency of the AT-rich interactive domain-containing 1B (ARID1B) gene is a genetic cause of ASD and ID. Our lab recently developed an Arid1b knockout mouse model to better study its role in the pathogenesis of these disorders. One theory regarding the cause of neurodevelopmental disorders …

Book Review: Phenomena Of Power: Authority, Domination, And Violence, Kerri J. Malloy

Faculty Research, Scholarly, and Creative Activity

No abstract provided.

Gasdermins In Apoptosis: New Players In An Old Game., Corey Rogers, Emad S. Alnemri

Department of Biochemistry and Molecular Biology Faculty Papers

Apoptosis is a form of programmed cell death (PCD) that plays critical physiological roles in removing superfluous or dangerous cell populations that are unneeded or threatening to the health of the host organism. Although the molecular pathways leading to activation of the apoptotic program have been extensively studied and characterized starting in the 1970s, new evidence suggests that members of the gasdermin superfamily are novel pore-forming proteins that augment apoptosis by permeabilizing the mitochondria and participate in the final stages of the apoptotic program by inducing secondary necrosis/pyroptosis. These findings may explain outstanding questions in the field such as why …

Euclidean Dynamical Triangulations: Running Couplings And Curvature Correlation Functions, Scott David Bassler

Dissertations - ALL

Quantum field theories have been incredibly successful at describing many fundamental aspects of reality with great precision, sometimes relying on the powerful computational tool of lattice methods. Gravity has so far eluded a quantum field theory description, leading many to consider alternate theories like String Theory. However, recent results in lattice quantum gravity have brought some renewed interest in the subject. After reviewing the progress made so far in Euclidean Dynamical Triangulations, a lattice theory of gravity, we examine how the couplings of the theory run with scale. We find that the dimensionless couplings $\hat{G}$ and $\hat{\Lambda}$ are not separately …

Understanding The Role Of Anisotropy On The Optoelectronic And Colloidal Properties Of Quantum Rods For Programmable Self-Assembly With Dna Origami, Yuetian Chen

Dissertations - ALL

Semiconductor nanocrystals, like quantum dots (QDs) and quantum rods (QRs), have tunable optoelectronic properties that depend on their composition, size and asymmetry. A small change in size or aspect ratio can lead to measurable changes in optical absorption and photoluminescence emission energies, as well as varied degrees of polarized optical behaviors at those energies. My dissertation research focuses on investigating the role of anisotropy on the optoelectronic and colloidal properties of quantum rods, as well as using DNA-mediated self-assembly to align these quantum rods on DNA origami for energy transfer applications in biocompatible systems. First, CdSe of systematically varied aspect …

Numerical Investigation Of Laser-Induced Ignition Phenomena, Deshawn Coombs

Dissertations - ALL

This thesis investigates various aspects of laser-ignition. Laser ignition is a form of combustion initiation by means of a focused laser pulse in a combustible mixture. The ignition process consists of a chain of processes with varying degrees of importance to the prediction of a successful flame propagation. Some of these processes include plasma formation, induced shock wave, emergence of a flame kernel, and successful transition to a self-sustained flame or flame quenching. This thesis will explore various aspects of this process using computational fluid dynamics and model analysis with the aim of identifying the controlling processes and simplified ways …

Digital Readout And Control Of A Superconducting Qubit, Caleb Jordan Howington

Dissertations - ALL

In the quest to build a fault-tolerant quantum computer, superconducting circuits based on Josephson junctions have emerged as a leading architecture. Coherence times have increased significantly over the last two decades, and processors with ∼ 50 qubits have been experimentally demonstrated. These systems traditionally utilize microwave frequency control signals, and heterodyne based detection schemes for measurement. Both of these techniques rely heavily on room temperature microwave generators, high-bandwidth lines from room temperature to millikelvin temperatures, and bulky non-reciprocal elements such as cryogenic microwave isolators. Reliance on these elements makes it impractical to scale existing devices up a single order of …

Locating People Of Interest In Social Networks, Pivithuru Wijegunawardana

Dissertations - ALL

By representing relationships between social entities as a network, researchers can analyze them using a variety of powerful techniques. One key problem in social network analysis literature is identifying certain individuals (key players, most influential nodes) in a network. We consider the same problem in this dissertation, with the constraint that the individuals we are interested in identifying (People of Interest) are not necessarily the most important nodes in terms of the network structure. We propose an algorithm to find POIs, algorithms to collect data to find POIs, a framework to model POI behavior and an algorithm to predict POIs …

Lifestyle Management For Vestibular Disorders, Michelle Pock

Student Capstone Papers

Individuals with vestibular disorders have concerns that impact lifestyle including limiting activities of daily living, limiting participation in social events, difficulty driving, and difficulty working (Cohen, 2014). Occupational therapists are able to help individuals with vestibular disorders by task analyzing symptom provoking activities, assessing the impact of symptoms on occupations, providing adaptations, and providing ways to modify environments (Gronski, Neville, Kannenberg, & Cohen, 2017). While occupational therapists are qualified to provide services to sustain and improve the occupational performance of individuals with vestibular disorders, occupational therapy is not well represented in this area particularly in addressing lifestyle components for vestibular …

The Histone Deacetylase Inhibitor Tubacin Mitigates Endothelial Dysfunction By Up-Regulating The Expression Of Endothelial Nitric Oxide Synthase., Jihui Chen, Jian Zhang, Noor F. Shaik, Bing Yi, Xin Wei, Xiao-Feng Yang, Ulhas P. Naik, Ross Summer, Guijun Yan, Xinyun Xu, Jianxin Sun

Center for Translational Medicine Faculty Papers

Endothelial nitric oxide (NO) synthase (eNOS) plays a critical role in the maintenance of blood vessel homeostasis. Recent findings suggest that cytoskeletal dynamics play an essential role in regulating eNOS expression and activation. Here, we sought to test whether modulation of cytoskeletal dynamics through pharmacological regulation of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation affects eNOS expression and endothelial function in vitro and in vivo.Wefound that tubulin acetylation inducer (tubacin), a compound that appears to selectively inhibit HDAC6 activity, dramatically increased eNOS expression in several different endothelial cell lines, as determined by both immunoblotting and NO production assays. Mechanistically, we found …

Distinguished Professor Known For Enthusiasm; Scholarship, Micky Bedell

UNH Today Archive

No abstract provided.

Evaluating The Effectiveness Of A Community-Based Youth Non-Profit Organization At Increasing Prosocial Behavior And Decreasing Antisocial Behavior Among Young Boys: A Pilot Study, Molly A. Miller

LSU New Orleans Theses and Dissertations

Community-based youth non-profit organizations (NPOs) have become increasingly popular for the provision of youth prevention and intervention services, yet many youth NPOs lack the resources to undergo formal evaluation. Further, most existing program evaluations do not consider individual characteristics of the child or the child’s exposure to stressors. The current pilot study sought to evaluate the extent to which boys participated in 1:1 mentoring and other program activities at the Son of a Saint (SOAS) NPO, an organization seeking to provide positive male role models for fatherless young boys. In addition, the current study examined the effects of program involvement …

Weathering The Storm: Black Maternal Mortality, Resistance, And Power In Richard Wright’S “Down By The Riverside,” Zora Neale Hurston’S Their Eyes Were Watching God, And Jesmyn Ward’S Salvage The Bones, Renee Vincent

LSU New Orleans Theses and Dissertations

Representations of natural disasters in Black Southern literature identify social location as the greatest indicator of risk vulnerability. Moreover, they can expose the precarious subjectivity of the Black female reproductive body, as addressed through characters Lulu in Richard Wright’s “Down by the Riverside,” Janie in Zora Neale Hurston’s Their Eyes Were Watching God, and Jesmyn Ward’s Esch in Salvage the Bones. Together, these female characters share a legacy of social marginalization and Black female resistance that is (re)shaped through their experiences with ecological catastrophe. This thesis considers these three texts together as an ongoing testimony and as a …

Meteorological Information Extraction Algorithm For Ship Routing, Zhaokun Wei, Xinlian Xie, Ming Wei, Tiantian Bao

Journal of Marine Science and Technology–Taiwan

The meteorological environment plays an important role when optimizing ship routing. Therefore, with the goal of obtaining meteorological environmental data associated with ship routing, an algorithm that can accurately obtain environmental data around a rhumb route in a standardized common data form is proposed. A Mercator projection is a type of equal-angle projection, and a rhumb route is a straight line on a Mercator chart. Consequently, the linear equation for a rhumb route can be achieved using the point-slope form. Based on this linear equation, points with a regular spacing whose degree is determined by the longitudinal size of the …

Digital Tools In The Classroom: Measuring The Effectiveness, Jeff Carpenter

Current Issues in Emerging eLearning

The purpose of the study is to determine if, compared to traditional practice, digital practice increases student measuring accuracy on an authentic task. Therefore the study explores the relative efficacy of digital versus traditional practice for increasing student measurement skills in applied situations. Research tells us that students’ poor performance with measuring skills is directly related to lack of practice. To increase the ability to accurately use a ruler, Junior High, Intermediate and Middle Schools students require more time on task than they typically spend practicing this skill. Since more time is hard to come by in the classroom, educators …

Pbrm1 Acts As A P53 Lysine-Acetylation Reader To Suppress Renal Tumor Growth., Weijia Cai, Liya Su, Lili Liao, Zongzhi Z Liu, Lauren Langbein, Essel Dulaimi, Joseph R Testa, Robert G Uzzo, Zhijiu Zhong, Wei Jiang, Qin Yan, Qing Zhang, Haifeng Yang

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

p53 acetylation is indispensable for its transcriptional activity and tumor suppressive function. However, the identity of reader protein(s) for p53 acetylation remains elusive. PBRM1, the second most highly mutated tumor suppressor gene in kidney cancer, encodes PBRM1. Here, we identify PBRM1 as a reader for p53 acetylation on lysine 382 (K382Ac) through its bromodomain 4 (BD4). Notably, mutations on key residues of BD4 disrupt recognition of p53 K382Ac. The mutation in BD4 also reduces p53 binding to promoters of target genes such as CDKN1A (p21). Consequently, the PBRM1 BD4 mutant fails to fully support p53 transcriptional activity and is defective …

Numerical Analysis Of Deep-Water Pipeline Abandonment And Recovery, Pan Gao, Bo-Wen Jin, Ji Zeng, Yi-Ting Zhan, Hui Zhou

Journal of Marine Science and Technology–Taiwan

Pipeline abandonment and recovery (A&R) is of great importance in offshore pipeline installation. A mathematical model of the A&R process is proposed based on the large deflection beam theory. To solve the model, an iteration process is adopted. The initial guess of the solution is obtained through the two-catenary approach, which significantly accelerates the iteration. A moving boundary technique is used to solve the governing equation of the suspended pipeline. With the proposed approach, the effects of the dominant parameters in the A&R process are studied. The cable length increases, and the maximum bending moment decreases, as the vessel moves …

The Tradition Of Cassava Rice Eating: Communication Patterns Of Sunda Wiwitan Indigenous Families In Cultural Heritage In Cireundeu Village, Cimahi City, West Java, Nanda Utaridah, Antar Venus, Atwar Bajari, Dadang Suganda

Library Philosophy and Practice (e-journal)

Abstract

The people of Cireundeu Village are known to hold firm Sundanese wiwitan customs and traditions of ancestral heritage that contain local wisdom. The tradition of eating cassava rice has been carried out by indigenous peoples for a hundred years since 1918 for generations. The process of introducing and applying the tradition of eating cassava rice was started by this traditional family in carrying out the inheritance of giving culture to the village of Cireundeu.

This research uses a qualitative method with a case study approach to three indigenous families in Cireundeu village who have different beliefs and birthplaces. As …

Mta3 Represses Cancer Stemness By Targeting The Sox2ot/Sox2 Axis, Liang Du, Lu Wang, Jinfeng Gan, Zhimeng Yao, Wan Lin, Junkuo Li, Yi Guo, Yuping Chen, Fuyou Zhou, Sai-Ching Jim Yeung, Robert P Coppes, Dianzheng Zhang, Hao Zhang

PCOM Scholarly Works

Cancer cell stemness (CCS) plays critical roles in both malignancy maintenance and metastasis, yet the underlying molecular mechanisms are far from complete. Although the importance of SOX2 in cancer development and CCS are well recognized, the role of MTA3 in these processes is unknown. In this study, we used esophageal squamous cell carcinoma (ESCC) as a model system to demonstrate that MTA3 can repress both CCS and metastasis in vitro and in vivo. Mechanistically, by forming a repressive complex with GATA3, MTA3 downregulates SOX2OT, subsequently suppresses the SOX2OT/SOX2 axis, and ultimately represses CCS and metastasis. More importantly, MTA3