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2019

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The Current Volume 30 : Issue 12, Nova Southeastern University Nov 2019

The Current Volume 30 : Issue 12, Nova Southeastern University

Student Newspapers

No abstract provided.


Data On The Endogenous Conversion Of Tyrosol Into Hydroxytyrosol In Humans., Anna Boronat, Julian Mateus, Natalia Soldevila-Domenech, Mercè Guerra, Jose Rodríguez-Morató, Carlota Varon, Daniel Muñoz, Francina Barbosa, Juan Carlos Morales, Andrea Gaedigk, Klaus Langohr, Maria-Isabel Covas, Clara Pérez-Mañá, Montserrat Fitó, Rachel F. Tyndale, Rafael De La Torre Nov 2019

Data On The Endogenous Conversion Of Tyrosol Into Hydroxytyrosol In Humans., Anna Boronat, Julian Mateus, Natalia Soldevila-Domenech, Mercè Guerra, Jose Rodríguez-Morató, Carlota Varon, Daniel Muñoz, Francina Barbosa, Juan Carlos Morales, Andrea Gaedigk, Klaus Langohr, Maria-Isabel Covas, Clara Pérez-Mañá, Montserrat Fitó, Rachel F. Tyndale, Rafael De La Torre

Manuscripts, Articles, Book Chapters and Other Papers

Here we present new and original data on the endogenous conversion of tyrosol (Tyr) into hydroxytyrosol (OHTyr) in humans and its effects on the cardiovascular system. A randomized, crossover, controlled clinical trial was performed with individuals at cardiovascular risk (n = 33). They received white wine (WW) (females 1, males 2 standard drinks/day), WW plus Tyr capsules (WW + Tyr) (25mg Tyr capsule, one per WW drink), and water (control) ad libitum. Intervention periods were of 4 weeks preceded by three-week wash-out periods. We assessed the conversion of Tyr to OHTyr, its interaction with a polygenic activity score (PAS) …


Transgenic Control Of Aflatoxin Contamination In Maize Through Host-Induced Gene Silencing Targeting Aspergillus Flavus Genes Encoding Polygalacturonase (P2c) And Versicolorin Dehydrogenase (Aflm), Yenjit Raruang Nov 2019

Transgenic Control Of Aflatoxin Contamination In Maize Through Host-Induced Gene Silencing Targeting Aspergillus Flavus Genes Encoding Polygalacturonase (P2c) And Versicolorin Dehydrogenase (Aflm), Yenjit Raruang

LSU Doctoral Dissertations

Maize (Zea mays L.) is susceptible to Aspergillus flavus infection and subsequent contamination with aflatoxins, the most potent naturally produced carcinogenic secondary metabolites. Here, the A. flavus gene aflM encoding the versicolorin dehydrogenase in aflatoxin biosynthesis and the p2c gene encoding the polygalacturonase that is involved in infection were selected as targets for suppression through host induced gene silencing (HIGS). A HIGS vector targeting these genes was constructed and introduced into immature B104 maize embryos. Thirteen out of fifteen p2c transformation events and six out of seven aflM events were confirmed positive by PCR. Kernels containing the p2c gene …


Food Habits Of Coyotes (Canis Latrans) In The Valles Caldera National Preserve, New Mexico, Suzanne J. Gifford, Eric M. Gese, Robert R. Parmenter Nov 2019

Food Habits Of Coyotes (Canis Latrans) In The Valles Caldera National Preserve, New Mexico, Suzanne J. Gifford, Eric M. Gese, Robert R. Parmenter

United States Department of Agriculture Wildlife Services: Staff Publications

Wildlife managers needed to understand coyote (Canis latrans) ecology in order to develop management plans on the nascent Valles Caldera National Preserve in northern New Mexico. Managers concerned about low elk (Cervus elaphus) recruitment had observed an increase in sightings of coyotes and observations of coyote predation on elk calves. Our objective was to identify and quantify coyote diet, and assess the temporal variation in coyote diet on the Valles Caldera National Preserve, particularly as related to elk calf consumption. We examined coyote food habits using 1,385 scats analyzed monthly from May 2005 to November 2008. …


Health Information Management- A Tool For Effective Health Care Delivery In Nigeria; Mother And Child Hospital, Akure, Ondo State Experience, Tajudeen Temitayo Adebayo Dr., Ebenezer Seun Orimoloye Mr Nov 2019

Health Information Management- A Tool For Effective Health Care Delivery In Nigeria; Mother And Child Hospital, Akure, Ondo State Experience, Tajudeen Temitayo Adebayo Dr., Ebenezer Seun Orimoloye Mr

Library Philosophy and Practice (e-journal)

The study investigates Health Information: A Tool for effective Health Care Delivery in Nigeria (Mother and Child Hospital, Akure Experience.). The descriptive survey design approach was employed and questionnaire was the research instruments. The patients, medical and paramedical staff (Doctors, HROs, Nurses, MLS and others) of the Mother and Child Hospital, Akure were used as the respondents; convenience sampling technique was adopted to get the samples involved. Two hundred questionnaires were administered and all were retrieved by the researcher and was used for this study. Data presentation and analysis were done using frequencies, simple percentages and chi-square statistics. The result …


Cactus-Based Mucilage As A Natural Dispersant For Crude Oil Spills, Fei Guo Nov 2019

Cactus-Based Mucilage As A Natural Dispersant For Crude Oil Spills, Fei Guo

USF Tampa Graduate Theses and Dissertations

Oil spills are a critical threat to the marine environment, and the spilled oil as a source of pollution can have long-term adverse effects on the marine ecosystem. Traditional mechanical clean-up operations have apparent advantages for dealing with small and medium-scale oil spills. For large-scale oil spills, dispersants are a practical and minimally influential approach to the environment. As the dispersant components are iteratively updated, dispersants become more efficient and safer. However, the toxicity of the dispersants remains a significant impediment to their application. An efficient and non-toxic dispersant is increasingly becoming a requirement.

The cactus mucilage extracts studied in …


The Adaptations Of The Sulfur-Oxidizing, Gammaproteobacterium "Candidatus Endoriftia Persephone", Endosymbiont Of The Giant Tubeworm Riftia Pachyptila, To Hydrothermal Vent Habitat Heterogeneity, Juliana M. Leonard Nov 2019

The Adaptations Of The Sulfur-Oxidizing, Gammaproteobacterium "Candidatus Endoriftia Persephone", Endosymbiont Of The Giant Tubeworm Riftia Pachyptila, To Hydrothermal Vent Habitat Heterogeneity, Juliana M. Leonard

USF Tampa Graduate Theses and Dissertations

The siboglinid tubeworm Riftia pachyptila is a dominant member of the deep-sea megafauna where seawater and hydrothermal vent (HTV) effluent interface and mix. It is one of the fastest growing invertebrates on land or in the sea. It does not have a digestive tract (e.g. mouth, gut, or anus), and is completely dependent on its sulfur-oxidizing endosymbiont, the Gammaproteobacterium “Candidatus Endoriftia persephone” for its nutritional requirements. This association was the first and is the most well studied among chemolithoautotrophic symbioses. “Ca. E. persephone” is a chemolithoautotrophic bacterium that oxidizes sulfide as an electron donor for energy, reduces oxygen as a …


Reducing Underrepresentation: Promising Practices In Florida, Catherine A. Mullins Nov 2019

Reducing Underrepresentation: Promising Practices In Florida, Catherine A. Mullins

USF Tampa Graduate Theses and Dissertations

In this study, I examined representation rates of gifted students from diverse backgrounds in Florida county school districts. Florida state legislation governing gifted student education allows for alternative identification methods to be used for students from underrepresented groups if plans for such identification are approved by the Florida Department of Education; however, this option, informally referred to as “Plan B” after subsection B of the legislation governing gifted services, is not a requirement that districts must follow. Consequently, there are large differences in the ways districts identify underrepresented students for gifted services. State legislation identifies underrepresented populations as students with …


Engineering Career Academies: A Comparison Of Middle School Student Academic Performance, Jakub D. Prokop Nov 2019

Engineering Career Academies: A Comparison Of Middle School Student Academic Performance, Jakub D. Prokop

USF Tampa Graduate Theses and Dissertations

A quasi-experimental study tested an integrated curriculum design in two career academies with engineering themes at the middle school level. Teachers in the engineering career academies, using the National Standards of Practice, implemented cross curricular units to middle school student cohorts. Participant cohorts ranged in sample sizes (n = 79, 155, 237, and 232) during the four years of analysis. Constructivism was used as a framework for the study and supported by integrated curriculum units. This study examined middle school students’ performance in reading and mathematics on state assessments of students in the engineering career academies to students not enrolled …


Compare Healthcare Utilization In The First Three Years Of Life For Infants With Prenatal Opioid Exposure Based On Type Of Neonatal Care Received, Renee Robinson, Amanda Slaunwhite, Evelyn Rider, Janet Johnson, Amanda Walch Nov 2019

Compare Healthcare Utilization In The First Three Years Of Life For Infants With Prenatal Opioid Exposure Based On Type Of Neonatal Care Received, Renee Robinson, Amanda Slaunwhite, Evelyn Rider, Janet Johnson, Amanda Walch

Journal of Health Disparities Research and Practice

Purpose/Background: Infants with prenatal opioid and other drug exposure often experience withdrawal symptoms known as neonatal abstinence syndrome (NAS). Some hospitals have modified clinical environments to promote recovery (reduced stimulation, nursery-like rooms, permitting rooming-in). While existing research has demonstrated efficacy of lower-stimulation environment, there is no known research evaluating longer-term implications of clinical environment on infant health beyond immediate neonatal period in states disproportionately affected by the opioid epidemic with diverse urban-rural populations such as Alaska.

Materials & Methods: The goal of this project is to determine whether supportive care decreases the likelihood of foster care placement from birth to …


Mountain West Clinical Translational Research-Infrastructure Network: Introduction, Parvesh Kumar Nov 2019

Mountain West Clinical Translational Research-Infrastructure Network: Introduction, Parvesh Kumar

Journal of Health Disparities Research and Practice

The Mountain West (MW) Clinical Translational Research Infrastructure Network (CTR- IN) Program represents a consortium of all of the 13 major public universities across seven Institutional Development Awards (IDeA) states with the overall goal of increasing and enhancing research capacity. The MW CTR-IN Program covers 1/3rd the U.S. land mass and almost 1/3rd of all IDeA states stretching across 4 time zones. The 13 major U.S. public partner universities in the 7 IDeA states are as follows: University of Alaska at Anchorage (UAA), University of Alaska at Fairbanks (UAF), University of Montana (UM), Montana State University (MSU), University …


The Relationship Between Maternal And Obese Children’S Daily Physical Activity., Shelby J. Foote, Alexandra Venezia, Darby J. Winkler, Keith R. Losche, Danielle D. Wadsorth Nov 2019

The Relationship Between Maternal And Obese Children’S Daily Physical Activity., Shelby J. Foote, Alexandra Venezia, Darby J. Winkler, Keith R. Losche, Danielle D. Wadsorth

International Journal of Exercise Science

International Journal of Exercise Science 12(5): 1302-1314, 2019. This study examined the effects of maternal influence on child’s daily physical activity. Participants consisted of eight families; parents (n = 9) and obese children (n = 10). Families were asked to attend exercise sessions at a university laboratory for 10 weeks. Daily physical activity was measured with a MovBand 3 which is a wrist worn accelerometer that records physical activity as moves. Linear mixed-effects models were used to predict daily physical activity over time and child physical activity as a function of parent physical activity on a day-to-day basis. …


Is The Ftp Test A Reliable, Reproducible And Functional Assessment Tool In Highly-Trained Athletes?, Eanna M. Mc Grath, Nicholas Mahony, Neil Fleming, Bernard Donne Nov 2019

Is The Ftp Test A Reliable, Reproducible And Functional Assessment Tool In Highly-Trained Athletes?, Eanna M. Mc Grath, Nicholas Mahony, Neil Fleming, Bernard Donne

International Journal of Exercise Science

International Journal of Exercise Science 12(4): 1334-1345, 2019. The aim of the current study was to assess reliability of the Functional Threshold Power test (FTP) and the corresponding intensity sustainable for 1-hour in a “quasi-steady state”. Highly-trained athletes (n = 19) completed four non-randomized tests over successive weeks on a Wattbike; a 3-min incremental test (GxT) to exhaustion, two 20-min FTP tests and a 60-min test at computed FTP (cFTP). Power at cFTP was calculated by reducing 20-min FTP data by 5% and was compared with power at Dmax and lactate threshold (TLac). Ventilatory and blood lactate …


Effect Of Capris In Validity Of Air-Displacement Plethysmography In Female College Students, Sydney Haynes, Joshua Miller, Kyle Susa Nov 2019

Effect Of Capris In Validity Of Air-Displacement Plethysmography In Female College Students, Sydney Haynes, Joshua Miller, Kyle Susa

International Journal of Exercise Science

International Journal of Exercise Science 12(4): 1315-1321, 2019. Body composition testing is completed in human performance laboratories, local health clubs, and many other locations each day. Maintaining proper technique is required to make sure the results are reliable and valid. The purpose of this study was to compare traditional clothing (spandex shorts and sports bra) and non-traditional clothing (Capri-length spandex pants and sports bra) in females while utilizing the Bod Pod to determine body composition. Nineteen female participants ages 18 - 25 years (Mage = 21.2 years) performed two Bod Pod tests either wearing traditional or non-traditional clothing when …


Acute Caffeine Ingestion Increases Velocity And Power In Upper And Lower Body Free-Weight Resistance Exercises, Thomas Degrange, William Jackson, Tyler Williams, Rebecca R. Rogers, Mallory Marshall, Christopher Ballmann Nov 2019

Acute Caffeine Ingestion Increases Velocity And Power In Upper And Lower Body Free-Weight Resistance Exercises, Thomas Degrange, William Jackson, Tyler Williams, Rebecca R. Rogers, Mallory Marshall, Christopher Ballmann

International Journal of Exercise Science

International Journal of Exercise Science 12(2): 1280-1289, 2019. The purpose of this study was to examine the acute effects of caffeine supplementation on velocity and power output during bench press and back squat exercises. Resistance trained males (n = 12) consuming less than 300 mg of caffeine daily, were recruited for this study. In a blinded crossover study design, participants supplemented with 6 mg· kg-1 caffeine or placebo (placebo, gluten-free cornstarch) 60 min prior to exercise. Participants completed 3 × 1 repetition with maximum explosive intent at 80% of their 1-RM for bench and squat exercises with two …


New Guidelines Lead To Improvement In Cholesterol Levels In Americans, But More Work Is Needed, Adam Pope Nov 2019

New Guidelines Lead To Improvement In Cholesterol Levels In Americans, But More Work Is Needed, Adam Pope

Browse All News

No abstract provided.


Adapting The Diabetes Prevention Program For Low And Middle-Income Countries: Protocol For A Cluster Randomised Trial To Evaluate 'Lifestyle Africa'., Delwyn Catley, Thandi Puoane, Lungiswa Tsolekile, Ken Resnicow, Kandace Fleming, Emily A. Hurley, Joshua M. Smyth, Mara Z. Vitolins, Estelle V. Lambert, Naomi Levitt, Kathy Goggin Nov 2019

Adapting The Diabetes Prevention Program For Low And Middle-Income Countries: Protocol For A Cluster Randomised Trial To Evaluate 'Lifestyle Africa'., Delwyn Catley, Thandi Puoane, Lungiswa Tsolekile, Ken Resnicow, Kandace Fleming, Emily A. Hurley, Joshua M. Smyth, Mara Z. Vitolins, Estelle V. Lambert, Naomi Levitt, Kathy Goggin

Manuscripts, Articles, Book Chapters and Other Papers

Introduction: Low and middle-income countries like South Africa are experiencing major increases in burden of non-communicable diseases such as diabetes and cardiovascular conditions. However, evidence-based interventions to address behavioural factors related to these diseases are lacking. Our study aims to adapt the CDC's National Diabetes Prevention Program (DPP) within the context of an under-resourced urban community in Cape Town, South Africa.

Methods/analysis: The new intervention (Lifestyle Africa) consists of 17 weekly sessions delivered by trained community health workers (CHWs). In addition to educational and cultural adaptations of DPP content, the programme adds novel components of text messaging and …


Prevalence And Risk Factors For Dyslipidemia Among Adults In Rural And Urban China: Findings From The China National Stroke Screening And Prevention Project (Cnsspp), Sampson Opoku, Yong Gan, Wenning Fu, Dajie Chen, Emmanuel Addo-Yobo, Diana Trofimovitch, Wei Yue, Feng Yan, Zhihong Wang, Zuxun Lu Nov 2019

Prevalence And Risk Factors For Dyslipidemia Among Adults In Rural And Urban China: Findings From The China National Stroke Screening And Prevention Project (Cnsspp), Sampson Opoku, Yong Gan, Wenning Fu, Dajie Chen, Emmanuel Addo-Yobo, Diana Trofimovitch, Wei Yue, Feng Yan, Zhihong Wang, Zuxun Lu

ETSU Faculty Works

Background: Dyslipidemia is a modifiable risk factor for cardiovascular disease (CVD). We investigated the prevalence and associated risk factors of dyslipidemia- raised total cholesterol (TC), raised triglycerides (TG), raised low-density lipoprotein (LDL-C), low high-density lipoprotein (HDL-C), and raised non-high-density lipoprotein (non-HDL-C) in rural and urban China. Methods: We analyzed data from 136,945 participants aged 40-100 years of the CNSSPP project for 2014. Dyslipidemia was defined by the NCEP-ATP III and the 2016 Chinese guidelines for the management of dyslipidemia in adults. Complete data on demographic, metabolic and lifestyle characteristics were used. Chi-square tests and multivariable logistic regression were used to …


Information Sources And Services For Using Research Scholars And Faculty Members In The School Of Life Science In Periyar University, Salam, Tamilnadu: A Case Study, Duraisekar S, Palaniappan M Nov 2019

Information Sources And Services For Using Research Scholars And Faculty Members In The School Of Life Science In Periyar University, Salam, Tamilnadu: A Case Study, Duraisekar S, Palaniappan M

Library Philosophy and Practice (e-journal)

This paper described that users visit the school of Life Science in Periyar University for collecting information from Research scholars and faculty members. The researchers have attempted to find out the perceptions and outlook of the university library users with highly response to utilize the facility is available. The study shows that the quality of collection with respect to books, Journals and e-resources. Purpose of using e-resources and satisfaction level of using e-resources. This study reveals that the accuser to spent more than one hours for searching e-resources. Access e-resources for preparing the papers for seminars and conferences at the …


Why We Love Community Engagement (And Your Chapter Will Too!), Kady L. Martini Nov 2019

Why We Love Community Engagement (And Your Chapter Will Too!), Kady L. Martini

Biennial Convention (CONV)

This presentation will explain how a small community service project turned into a community engagement partnership that will service both the community and the Epsilon Chapter of Sigma Theta Tau International for years to come.


Elderly Health Services At Senior Centers In An Urban South Korean Community, Boas Yu Nov 2019

Elderly Health Services At Senior Centers In An Urban South Korean Community, Boas Yu

Biennial Convention (CONV)

The purpose of this study was to identify the current status of elderly health services provided by senior centers in South Korea and to pinpoint any improvements or recommendations needed for the South Korean senior centers to better serve elderly population.


Mhealth Intervention To Prevent College Students Hazardous Drinking For College Students: A Randomized Trial, Donna Kazemi Nov 2019

Mhealth Intervention To Prevent College Students Hazardous Drinking For College Students: A Randomized Trial, Donna Kazemi

Biennial Convention (CONV)

Participants should expect to learn about mHealth technology advances to deliver interventions to address risky behaviors among young adults. Particularly of interest to nurse practitioners and school health nurses since mHealth interventions have the potential to be effective interventions to address risky drinking among students.


“We Can Learn Some Things From Them, But They Can Learn Some Things From Us Too”: Intergenerational Perceptions Of Shared Infant Feeding Information, Alexis L. Woods Barr Nov 2019

“We Can Learn Some Things From Them, But They Can Learn Some Things From Us Too”: Intergenerational Perceptions Of Shared Infant Feeding Information, Alexis L. Woods Barr

USF Tampa Graduate Theses and Dissertations

Breastfeeding is associated with unparalleled benefits for infants, mothers, families and society. In light of the breastfeeding disparities and health disparities experienced by the African American community, their women and children stand to gain the most from breastfeeding practices compared to other first-food feeding methods. Moreover, African American mothers are constantly exposed to messages, images, and stereotypes about motherhood (from multiple channels of communication) which influences their infant feeding practices. Many of these exposures send mixed messages and tend to be cultural contradictions of Black motherhood. What complicates this issue is the shortage of research that investigates the intergenerational infant …


“Man Plans But Ultimately, God Decides”: A Phenomenological Investigation Of The Contextual Family Planning Beliefs Of Recently Resettled Congolese Refugee Women In West Central Florida., Linda Bomboka Wilson Nov 2019

“Man Plans But Ultimately, God Decides”: A Phenomenological Investigation Of The Contextual Family Planning Beliefs Of Recently Resettled Congolese Refugee Women In West Central Florida., Linda Bomboka Wilson

USF Tampa Graduate Theses and Dissertations

Existent demographic changes in the United States are largely a result of the current international refugee crisis. Within the past three years, there has been an influx of refugees who were affected by the wars in the Democratic Republic of Congo (DRC). Congolese refugees were the highest number of all refugee groups to arrive in the United States in Fiscal Years 2016-2018, yet little is known about their lived experiences, particularly as they apply to reproductive health and family planning in general. Congolese refugee women who resettle in the United States are unique because many lived in refugee camps for …


The Growth And Development Of Sweet Basil (Ocimum Basilicum) And Bush Basil (Ocimum Minimum) Grown Under Three Light Regimes In A Controlled Environment, Mohammed Aldarkazali, Hail Z. Rihan, Demelza Carne, Michael P. Fuller Nov 2019

The Growth And Development Of Sweet Basil (Ocimum Basilicum) And Bush Basil (Ocimum Minimum) Grown Under Three Light Regimes In A Controlled Environment, Mohammed Aldarkazali, Hail Z. Rihan, Demelza Carne, Michael P. Fuller

School of Biological and Marine Sciences

Light is a crucial element for plant growth and production. In areas where natural light is not sufficient for optimal plant growth and production, high pressure sodium (HPS) light sources are widely used. However, HPS lamps are considered not very electrically efficient generating high radiant heat and as a consequence, there has been a lot of interest in replacing HPS lamps with new more efficient lighting sources in the form of light-emitting diodes (LEDs). The effects of three lighting sources (White LED, Blue/Red LED and HPS) on the growth, development and on the essential oil yield and quality of sweet …


Racism, Bias, And Discrimination As Modifiable Barriers To Breastfeeding For African American Women: A Scoping Review Of The Literature, Karen Marie Robinson, Alissa Fial, Lisa Hanson Nov 2019

Racism, Bias, And Discrimination As Modifiable Barriers To Breastfeeding For African American Women: A Scoping Review Of The Literature, Karen Marie Robinson, Alissa Fial, Lisa Hanson

College of Nursing Faculty Research and Publications

Introduction

Although breastfeeding has been shown to improve health outcomes for infants, African American women initiate and continue breastfeeding at lower rates than women from other racial groups. This scoping review was conducted to assess the effect racism, bias, and discrimination have on breastfeeding care, support, and outcomes for African American women.

Methods

A scoping review was performed of the literature published between January 2010 through December 2019 using databases MEDLINE via PubMed, CINAHL, Cochrane Library, PsycINFO, and Sociological Abstracts. Studies that examined racism, bias, or discrimination with breastfeeding as an outcome were included. After a review of titles and …


Biochar Incorporation Increased Nitrogen And Carbon Retention In A Waste-Derived Soil, H. Kate Schofield, T. R. Pettitt, Alan D. Tappin, Gavyn K. Rollinson, Mark F. Fitzsimons Nov 2019

Biochar Incorporation Increased Nitrogen And Carbon Retention In A Waste-Derived Soil, H. Kate Schofield, T. R. Pettitt, Alan D. Tappin, Gavyn K. Rollinson, Mark F. Fitzsimons

School of Geography, Earth and Environmental Sciences

No abstract provided.


Perceptions Of The Effectiveness Of Food Policy Coalitions In Strengthening Community Food Security In The United States., Joseph G. England Iii Nov 2019

Perceptions Of The Effectiveness Of Food Policy Coalitions In Strengthening Community Food Security In The United States., Joseph G. England Iii

USF Tampa Graduate Theses and Dissertations

Food insecurity is experienced most acutely and addressed most innovatively at the community level to which the concept of community food security (CFS) finds purchase (Hamm and Bellows, 2003). In recognition of the many varying dynamics embedded in the CFS concept, Food Policy Coalitions have become an organizational model adapted by communities across the United States. While FPCs have grown in number considerably over the last decade, there remains a considerable lack of empirical research documenting evaluation and engagement methods, as well as strategies used to address community food security. This research, framed by the Community Coalition Action Theory, draws …


Role Of The Conserved Ndr/Lats Kinase Orb6 In Controlling Cell Growth And Stress Adaptation, Chuan Chen Nov 2019

Role Of The Conserved Ndr/Lats Kinase Orb6 In Controlling Cell Growth And Stress Adaptation, Chuan Chen

Open Access Dissertations

Adaptation to the nutritional environment is critical for all cells. RAS GTPase is a highly conserved GTP binding protein with crucial functions for cell growth and differentiation in response to environmental conditions. Inappropriate activation of human RAS GTPase has a causal role in cancer, congenital malformations, and neurodevelopmental disorders. Our lab previously found that the conserved NDR kinase Orb6 regulates the mRNA and protein levels of Ras1 guanine nucleotide exchange factor (GEF) Efc25, by controlling the coalescence of the mRNA-binding protein Sts5 into ribonucleoprotein (RNP) granules. However, it is still unclear whether the Orb6-Sts5 axis regulates RAS GTPase activity in …


Speaker Biographies, Sienna Craig, John Kopper Nov 2019

Speaker Biographies, Sienna Craig, John Kopper

Women on the Faculty: A Dartmouth Centennial

This document contains the biographies of all of the event speakers.