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2019

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Standardization Of Postoperative Care Guidelines For Pediatric Cleft Palate Patients, Tatyana Grib, Macy Therese G. Andrada, Julie C. Barragan, Amanda K. Dailor, Samantha T. Gerber, Mercedes S. Greenberg Dec 2019

Standardization Of Postoperative Care Guidelines For Pediatric Cleft Palate Patients, Tatyana Grib, Macy Therese G. Andrada, Julie C. Barragan, Amanda K. Dailor, Samantha T. Gerber, Mercedes S. Greenberg

Master's Projects and Capstones

At a large, community-based pediatric hospital in Southern California, a quality improvement project commenced with a goal to improve patient outcomes by decreasing length of stay and pain levels, while increasing toleration of feeds. Implementing a standardized guideline would ensure safe practice across the continuum and allow providers to use a systematic tool for postoperative care, including nursing care interventions and medications. The Root-Cause- Analysis tool was used to assess the microsystem and determine the contributing factors to the identified problem. A SWOT analysis was then performed, followed by a plan to collect data from all pediatric cleft palate procedures …


Conceptualizing The Promise Of Life Skills Education For Adolescent Girls In The Global South: A Critical Discourse Analysis, Olivia Casey Dec 2019

Conceptualizing The Promise Of Life Skills Education For Adolescent Girls In The Global South: A Critical Discourse Analysis, Olivia Casey

Master's Theses

In recent years, international development organizations have increasingly championed life skills education as a crucial tool for empowering girls in the global South. However, while life skills education continues to gain momentum and popularity within the international development landscape, the heterogeneity of life skills interventions remains significant. In this study, I aimed to uncover how key global actors differently conceptualize life skills and the promises they are understood to hold for adolescent girls in the global South at the current moment. Utilizing the methodology of critical discourse analysis, I examined key documents on girls’ life skills education published by central …


Disaggregated Hispanic Groups And Cancer: Importance, Methodology, And Current Knowledge, Paulo S. Pinheiro, Karen E. Callahan, Erin N. Kobetz Dec 2019

Disaggregated Hispanic Groups And Cancer: Importance, Methodology, And Current Knowledge, Paulo S. Pinheiro, Karen E. Callahan, Erin N. Kobetz

Environmental & Global Health Faculty Research

Cancer is the leading cause of death among Latinos/Hispanics, the largest racial/ethnic minority group in the United States. Their cancer burden has nearly doubled in 15 years, with 129,000 new cancer cases nationwide in 2014. As this relatively young Hispanic population ages, this burden will inevitably increase; thus, accurate characterization of the Hispanic cancer experience is critical. In this chapter, we summarize the current knowledge on cancer in Hispanics, with a focus on the imperative of disaggregating by specific Hispanic group (Mexicans, Puerto Ricans, Cubans, Central Americans, South Americans, and Dominicans) and nativity. We also describe for the first time …


Postharvest Heat Treatments To Inhibit Penicillium Digitatum Growth And Maintain Quality Of Mandarin (Citrus Reticulata Blanco), Diana B. Queb-Gonzalez, Aurelio Lopez-Malo, María E. Sosa-Morales, Rossana Villa-Rojas Dec 2019

Postharvest Heat Treatments To Inhibit Penicillium Digitatum Growth And Maintain Quality Of Mandarin (Citrus Reticulata Blanco), Diana B. Queb-Gonzalez, Aurelio Lopez-Malo, María E. Sosa-Morales, Rossana Villa-Rojas

Department of Food Science and Technology: Faculty Publications

Use of fungicides is a common practice as a postharvest treatment to control fruit decay. Nowadays, environment-friendly technologies, such as heat treatments, are viable replacements. This study evaluated the effects of post-harvest heat treatments (traditional and microwave-assisted) on mandarins intentionally inoculated with Penicillium digitatum. For the studied heat treatments, the target temperature was 50C, which was held for 2.5 min. After heating, mandarins were cooled and stored at 25C for 13 days. MW treatments effectively prevented mold growth during storage, while HW only delayed it. Control mandarins (without treatment) showed the highest significant weight loss. Neither thermal treatment nor storage …


Behavior Skills Training To Improve Parent Treatment Fidelity And Generalization In A Feeding Program, Melissa Stiffler Dec 2019

Behavior Skills Training To Improve Parent Treatment Fidelity And Generalization In A Feeding Program, Melissa Stiffler

Electronic Theses & Dissertations

Feeding problems are five times more likely to occur in children with autism spectrum disorder (ASD) than in typically developing peers (Sharp, et al., 2013). Though behavior analytic protocols have demonstrated efficacy, less research has investigated methods to transfer technology to non–professional caregivers. This study utilized a behavioral skills training (BST) procedure to increase generalization of treatment methods from the clinic to the home environment for three parent-child dyads. Meal observations were conducted prior to treatment to determine baseline rates of behavior, specifics of the child’s food refusal, oral motor deficits, and nutritional needs. Baseline observations were used to develop …


Housing Prices And Household Savings: Evidence From Urban China, Weida Kuang, Tao Li, Jing Jian Xiao Dec 2019

Housing Prices And Household Savings: Evidence From Urban China, Weida Kuang, Tao Li, Jing Jian Xiao

Human Development and Family Science Faculty Publications

Based on precautionary saving motives, this research develops a three-period life-cycle model to manifest the impact of housing prices on household savings in urban China. The theoretical model illustrates that the expected appreciation of housing prices at a household’s middle age leads to the increase in household savings at a household’s young age. Second, household savings at a household’s young age are positively associated with both expected educational and medical expenditures in a household’s middle age and pension expenditures at a household’s old age. Third, the expected housing prices crowd out educational and medical expenditures at a household’s middle age. …


Standardization Of Postoperative Care Guidelines For Pediatric Cleft Palate Patients, Amanda Dailor, Macy Therese G. Andrada, Julie C. Barragan, Samantha T. Gerber, Mercedes S. Greenberg, Tatyana Grib Dec 2019

Standardization Of Postoperative Care Guidelines For Pediatric Cleft Palate Patients, Amanda Dailor, Macy Therese G. Andrada, Julie C. Barragan, Samantha T. Gerber, Mercedes S. Greenberg, Tatyana Grib

Master's Projects and Capstones

At a large, community-based pediatric hospital in Southern California, a quality improvement project commenced with a goal to improve patient outcomes by decreasing length of stay and pain levels, while increasing toleration of feeds. Implementing a standardized guideline would ensure safe practice across the continuum and allow providers to use a systematic tool for postoperative care, including nursing care interventions and medications. The Root-Cause-Analysis tool was used to assess the microsystem and determine the contributing factors to the identified problem. A SWOT analysis was then performed, followed by a plan to collect data from all pediatric cleft palate procedures performed …


Strategic Success: The Ansoff Matrix Vs. The Balanced Scorecard, Christian Cleberg Dec 2019

Strategic Success: The Ansoff Matrix Vs. The Balanced Scorecard, Christian Cleberg

Honors Program: Senior Projects (Public)

Academic and professional research has proven that strategic planning and management frameworks have tremendous impact on an organization’s success. However, these studies do not opine on the usability and fit of strategic frameworks within an organization. This paper examines the composition of two popular frameworks, the Ansoff matrix and the balanced scorecard, and illustrates the various ways that these frameworks have found success in the corporate world. It also compares and contrasts the frameworks’ differing structures and offers recommendations for how these frameworks may be applied to companies with diverse goals and missions.


Using Engagement Journalism To Serve The Needs Of Caregivers Of People With Autism, Ariam Alula Dec 2019

Using Engagement Journalism To Serve The Needs Of Caregivers Of People With Autism, Ariam Alula

Capstones

I’m Ariam. I worked with a diverse group of families who are intimately impacted by the autism spectrum disorder and other disabilities through caring for a loved one with the diagnosis. During the program, I used my journalism education, advocacy work, and interpersonal skills to support the emotional and informational needs of the community. The majority of the caretakers I engaged over the duration of the program reside in the Bronx, my home borough. I chose to focus on the lived experiences of people in this community because they represent my own. I have an older brother on the spectrum …


Multiple Mitochondrial Thioesterases Have Distinct Tissue And Substrate Specificity And Coa Regulation, Suggesting Unique Functional Roles., Carmen Bekeova, Lauren Anderson-Pullinger, Kevin Boye, Felix Boos, Yana Sharpadskaya, Johannes M Herrmann, Erin L. Seifert Dec 2019

Multiple Mitochondrial Thioesterases Have Distinct Tissue And Substrate Specificity And Coa Regulation, Suggesting Unique Functional Roles., Carmen Bekeova, Lauren Anderson-Pullinger, Kevin Boye, Felix Boos, Yana Sharpadskaya, Johannes M Herrmann, Erin L. Seifert

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Acyl-CoA thioesterases (Acots) hydrolyze fatty acyl-CoA esters. Acots in the mitochondrial matrix are poised to mitigate β-oxidation overload and maintain CoA availability. Several Acots associate with mitochondria, but whether they all localize to the matrix, are redundant, or have different roles is unresolved. Here, we compared the suborganellar localization, activity, expression, and regulation among mitochondrial Acots (Acot2, -7, -9, and -13) in mitochondria from multiple mouse tissues and from a model of Acot2 depletion. Acot7, -9, and -13 localized to the matrix, joining Acot2 that was previously shown to localize there. Mitochondria from heart, skeletal muscle, brown adipose tissue, and …


Art-Based Health Education For Homeless And Marginally Housed Women In San Francisco, Trineca R-N Godfrey Dec 2019

Art-Based Health Education For Homeless And Marginally Housed Women In San Francisco, Trineca R-N Godfrey

Master's Projects and Capstones

San Francisco currently has the highest rate of unsheltered homeless persons in the United States. Between limited resources and stigma many women included in this most vulnerable population are left with little to no support. Cis women as well as trans and non- binary people are at high risk for negative mental health outcomes due to violence (physical and psychological), stigma, lack of social support, societal marginalization, and the lack of healthcare. Lyon-Martin Health Services and the Women’s Community Clinic, in San Francisco’s Mission Neighborhood, caters to this community through its Outreach Department. Following a staff and outreach client needs …


Characterization Of Fatty Acid Composition Of Bull Sperm With Varied Cryotolerance, Holly Evans Dec 2019

Characterization Of Fatty Acid Composition Of Bull Sperm With Varied Cryotolerance, Holly Evans

Theses and Dissertations

The objectives of this study were to determine fatty acid composition and acrosome status from bull sperm with different freezabilities (n = 12). We hypothesized that lipid fractions had differentiated fatty acid compositions and such differences influence sperm freezability and the sperm acrosome. Fatty acids were extracted from fresh frozen sperm and fractionated by solid-phase extraction. Thirtyour fatty acids were quantified. Saturated fatty acids were predominant, accounting for 71 to 80% of fatty acids in both fractions. Differences in composition between fractions existed (P < 0.001). Branched chain fatty acid concentrations (15 to 18 µg) were almost twice that of polyunsaturated fatty acid concentrations found in the polar fractions (8 to 9 µg; P < 0.001). Sperm with differentiated freezabilities had few differences in 22:0, 18:1 cis 9, and 14:0 13-methyl fatty acids (P ≤ 0.011). Analyses of acrosome status of sperm revealed that acrosomes were affected differently among bulls.


Effects Of The In Ovo Injection Of Vitamin D3 Sources On The Hatchability, Performance, Breast Meat Yield, Small Intestine Morphology, And Immunity Of Ross 708 Broilers Subjected To Dietary Insufficiency And Pathogenic Agents, Seyed Abolghasem Fatemi Dec 2019

Effects Of The In Ovo Injection Of Vitamin D3 Sources On The Hatchability, Performance, Breast Meat Yield, Small Intestine Morphology, And Immunity Of Ross 708 Broilers Subjected To Dietary Insufficiency And Pathogenic Agents, Seyed Abolghasem Fatemi

Theses and Dissertations

Effects of varying dosages (0.6 to 4.8 μg/egg) of vitamin D3 (D3) and 25-hydroxycholecalciferol (25OHD3), administrated by in ovo (amniotic) injection, on various embryonic and post-hatch physiological variables in Ross 708 broilers were investigated. The in ovo injection of 1.2 to 4.8 μg of both D3 and 25OHD3 increased serum 25OHD3 concentrations in broiler embryos in comparison to non-injected and diluent-injected control groups. Furthermore, the effects of 2.4 μg of D3 and 25OHD3 alone and in combination on the performance, meat yield and quality, small intestine morphology, and immunity of the broilers fed a diet restricted in calcium and phosphorous …


Effect Of Pro- And Prebiotics On The Apparent Digestibility Of Nutrients And Identification Of Fecal Bacterial Isolatew In The Sedentary And Exercising Horse, Courtney Heaton Dec 2019

Effect Of Pro- And Prebiotics On The Apparent Digestibility Of Nutrients And Identification Of Fecal Bacterial Isolatew In The Sedentary And Exercising Horse, Courtney Heaton

Theses and Dissertations

The primary objectives of the following experiments were to: 1) determine the impact of a directed microbial (DFM) blend on digestibility and microbial populations on horses fed low (LQ) and high (HQ) quality hay, 2) evaluate the differences in diet digestibility, microbial populations, and blood metabolites due to DFM supplementation to the exercising horse, 3) assess the impact of short-chain fructooligosaccharide (scFOS) supplementation on digestibility and the fecal microbial ecosystem in senior (SR) vs. mature (MA) horses, and 4) determine the relationship between insulin dysregulation (ID) and morphometric neck measurements (MNM) in the non-obese stock-type horse. Results indicated that: 1) …


Evaluation Of Health, Production Parameters, Time To First Detected Estrus, And Behavior In Dairy Cows Treated With Pegbovigrastim, Mauricio Xavier Da Silva Oliveira Dec 2019

Evaluation Of Health, Production Parameters, Time To First Detected Estrus, And Behavior In Dairy Cows Treated With Pegbovigrastim, Mauricio Xavier Da Silva Oliveira

Theses and Dissertations

Pegbovigrastim injection (IMR) represents a new approach in overcoming mastitis. The objective of this study was to evaluate production parameters, overall health, time to first detected heat, and behavior of cows treated with IMR or a saline control. Study cows (n = 270) were blocked by parity group (multiparous or primiparous) and randomly assigned to control (CON, n = 144) or treatment (IMR, n = 126). Milk yield, fat, protein, lactose, solids nonfat percent, somatic cell count, and body condition, hygiene, and lameness were evaluated weekly. Animals were evaluated for metritis twice weekly via evaluation of rectal temperature, per rectum …


How The Dogface Got Its Color: How Genetics And The Environment Influence Color Variation Within And Between Species In The Zerene Butterfly, Jennifer Fenner Dec 2019

How The Dogface Got Its Color: How Genetics And The Environment Influence Color Variation Within And Between Species In The Zerene Butterfly, Jennifer Fenner

Theses and Dissertations

A fundamental question in biology is: How is variation generated? At a basic level, the vast amount of variation and biodiversity is generated through a combination of genetic and environmental processes. Traditionally these processes were treated independently, but recently fields such as evolutionary development have worked to unify our understanding of these mechanisms and to investigate how these processes interact with each other to generate variation. Developmental plasticity provides a fantastic framework for studying how genetic and environmental (GxE) interactions shape and maintain natural variation. Butterflies and their wing color patterns have long been model systems for plasticity. This dissertation …


Rice (Oryza Sativa) Response To Sub-Lethal Concentrations Of Crop Desiccants, Justin M. Mccoy Dec 2019

Rice (Oryza Sativa) Response To Sub-Lethal Concentrations Of Crop Desiccants, Justin M. Mccoy

Theses and Dissertations

Research was conducted at the Mississippi State University Delta Research and Extension Center from 2016 to 2018 to determine the effects of sub-lethal concentrations of paraquat, glyphosate, saflufenacil, and sodium chlorate exposure to rice at late-season growth stages, determine the effects of exposure to sub-lethal concentrations of glyphosate or paraquat on multiple rice cultivars, and characterize the effects of paraquat exposure and Oebalus pugnax feeding on rice grain quality. In the current research, rough rice grain yields were reduced by exposure to sub-lethal concentrations of soybean desiccants 0 to 28 DAH. Rice injury was determined to not be an accurate …


Perceptions Of Food, Supportive Resistance Resources, And Nutrition Knowledge Of Bariatric Surgery Patients, Savannah K. Walker Dec 2019

Perceptions Of Food, Supportive Resistance Resources, And Nutrition Knowledge Of Bariatric Surgery Patients, Savannah K. Walker

Theses and Dissertations

Adult overweight and obesity is a life-threatening health concern worldwide. Bariatric surgery is a successful treatment for severely obese individuals however, there is a moderate risk for weight regain. This study evaluated perception of food, supportive resistance resources, and nutrition knowledge, which play important roles in successful weight loss post bariatric surgery. Participants completed a three-part questionnaire at three time intervals: prior to surgery, 2 months post-surgery, and 5 months post-surgery. Results show that bariatric patients’ eating behavior significantly changes post bariatric surgery, but a disordered perception of food remains. Bariatric surgery patients believe support from significant others and family …


Impact Of Refrigerated Storage On The Dissipation Of Woody Broiler Breast Meat, Michael Byron Dec 2019

Impact Of Refrigerated Storage On The Dissipation Of Woody Broiler Breast Meat, Michael Byron

Theses and Dissertations

Chicken breast samples, (n=90; n=30 normal, n=30 moderate woody breast (WB), n=30 severe WB) were collected from a commercial processing plant on 5 separate occasions. After 5 days of storage at 2-4 ºC, 84% of severe WB fillets dissipated to moderate WB, which was greater (P<0.05) than all other storage times. In comparison, 40-52% of the moderate WB fillets dissipated to slight WB or normal breasts after 3 to 5 days of storage. Shear force was greater (P<0.05) for normal breast meat than moderate and severe WB meat on day 0. After 2, 3, 4, and 5 days of storage the upper position (cranial part) of severe WB had greater shear force than normal fillets (P<0.05). Therefore, the dissipation that occurred in woody breast meat over refrigerated storage was apparent through palpation but did not result in improved texture in the cranial portion of the breast, based on shear force results.


Docosahexaenoic Acid Consumption Impedes Early Interferon- And Chemokine-Related Gene Expression While Suppressing Silica-Triggered Flaring Of Murine Lupus, Abby D. Benninghoff, Melissa A. Bates, Preeti S. Chauhan, Kathryn A. Wierenga, Kristen N. Gilley, Andrij Holian, Jack R. Harkema, James J. Pestka Dec 2019

Docosahexaenoic Acid Consumption Impedes Early Interferon- And Chemokine-Related Gene Expression While Suppressing Silica-Triggered Flaring Of Murine Lupus, Abby D. Benninghoff, Melissa A. Bates, Preeti S. Chauhan, Kathryn A. Wierenga, Kristen N. Gilley, Andrij Holian, Jack R. Harkema, James J. Pestka

Animal, Dairy, and Veterinary Science Faculty Publications

Exposure of lupus-prone female NZBWF1 mice to respirable crystalline silica (cSiO2), a known human autoimmune trigger, initiates loss of tolerance, rapid progression of autoimmunity, and early onset of glomerulonephritis. We have previously demonstrated that dietary supplementation with the ω-3 polyunsaturated fatty acid docosahexaenoic acid (DHA) suppresses autoimmune pathogenesis and nephritis in this unique model of lupus flaring. In this report, we utilized tissues from prior studies to test the hypothesis that DHA consumption interferes with upregulation of critical genes associated with cSiO2-triggered murine lupus. A NanoString nCounter platform targeting 770 immune-related genes was used to assess …


Understanding The Effects Of Mass Mortality Events On Plant Communities And Consumer Behavior, Carolina Baruzzi Dec 2019

Understanding The Effects Of Mass Mortality Events On Plant Communities And Consumer Behavior, Carolina Baruzzi

Theses and Dissertations

Mass mortality events (MMEs) are die-offs that result in increased carrion biomass and sometimes the impairment of functional roles. Concurrently, several vulture species are declining. Carrion is a basal resource in ecosystems and its recycling by vultures is considered an ecosystem service. However, the consequences of simultaneously increasing carrion loads and declining vulture populations are unknown. I developed a theoretical framework predicting that, with increasing carrion biomass, carrion food web diversity would increase horizontally and vertically, respectively increasing and decreasing carrion recycling efficiency. Using a manipulative experiment, I investigated the role of bottom-up and top-down forces affecting plant communities during …


Vegetable, Dietary Fiber Consumption And Obesity In Japan And The United States, Megumi Hashida Dec 2019

Vegetable, Dietary Fiber Consumption And Obesity In Japan And The United States, Megumi Hashida

Theses and Dissertations

The US and Japanese populations do not meet recommended DF intakes. This study indicated the relationship between the variety of vegetables available in markets and vegetable consumption in the US and Japan. The number of vegetables available in markets was determined using online resources from five markets in each country. Mean number of vegetable products in the US was 104.4 products (SD: ±36.8) and mean number of vegetable products in the Japanese markets was 120.2 products (SD: ±15.6). There was no significant relationship between the variety of vegetables in markets and vegetable consumption between the US and Japan. This study …


The Nurse’S Role In Prognosis-Related Communication In Pediatric Oncology Nursing Practice, Amy Rose Newman, Lauri Linder, Kristin Haglund Dec 2019

The Nurse’S Role In Prognosis-Related Communication In Pediatric Oncology Nursing Practice, Amy Rose Newman, Lauri Linder, Kristin Haglund

College of Nursing Faculty Research and Publications

The experiences of pediatric oncology nurses with prognosis-related communication (PRC) remain largely unknown. The purpose of this article is to report results of focus groups wherein 15 pediatric oncology nurses from three Midwestern pediatric cancer programs provided descriptions of PRC and how they experience PRC within their daily practice. Data from focus groups were analyzed via an interpretive descriptive approach, which resulted in three themes: (1) nurses’ operational definition of PRC, (2) nurses’ roles in PRC, and (3) nurses’ preparation for engagement in PRC. From discussions within the focus groups, nurses recognized that PRC occurs across a continuum. Nurses distinguished …


Novel Host-Bacterial Symbioses Revealed: Characterization Of Wolbachia In Arthropods Of Western North America, Joanne P. Odden, Wyatt Eng, Kelsey Lee, Helen Donelick, Mallory Hiefield, Jamie Steach, Lauren Chan Dec 2019

Novel Host-Bacterial Symbioses Revealed: Characterization Of Wolbachia In Arthropods Of Western North America, Joanne P. Odden, Wyatt Eng, Kelsey Lee, Helen Donelick, Mallory Hiefield, Jamie Steach, Lauren Chan

Western North American Naturalist

Arthropod-bacterial symbioses are prevalent and play significant roles in ecosystems and the economy, and in some cases, habitat invasion. Wolbachia bacteria form symbiotic associations with a wide range of arthropod hosts and can affect both host reproduction and resistance to viral infections. The extent to which Wolbachia infects different arthropod species is fundamental not only to host biology, but also to the health of humans, ecosystems, and agriculture. Much of what we know about the effects of Wolbachia comes from a few key taxa, such as the model organism Drosophila melanogaster and the mosquito vector of human disease, Aedes aegypti …


Bio Buzz Newsletter, Issue 18, December 2019, Denison Biology Department Dec 2019

Bio Buzz Newsletter, Issue 18, December 2019, Denison Biology Department

Biology Buzz Newsletter

No abstract provided.


School Of Culinary Arts & Food Technology-Winter Newsletter 2019, James Murphy Dec 2019

School Of Culinary Arts & Food Technology-Winter Newsletter 2019, James Murphy

Other resources

The School of Culinary Arts and Food Technology, TU Dublin, Autumn Newsletter captured the many events, research, awards, significant contributions and special civic and community activities which the students and staff members of the school have successfully completed up to the Winter period of 2019. The successful completion of these activities would not be possible without the active and on-going support of the 'INSPIRED' friends of Culinary Arts (school supporters) and our school's industry association supporters.


Nucleus Pulposus Of The Intervertebral Disc: The Effect Of Environmental Factors On Metabolic Activity, Lukas M. Jaworski Dec 2019

Nucleus Pulposus Of The Intervertebral Disc: The Effect Of Environmental Factors On Metabolic Activity, Lukas M. Jaworski

Open Access Dissertations

Lower back pain is a major socioeconomic concern in developed nations. Moreover, it is a condition which a majority of people will experience an episode within their lifetime, with a portion becoming chronically afflicted. Degeneration of the intervertebral disc (IVD) is believed to play a critical role in initiating lower back pain. Poor nutrient supplies are implicated as a one of the root causes of this degeneration and much effort has been spent to better elucidate the behavior of IVD cells. The IVD is the largest avascular structure within the body, relying on diffusion to migrate nutrients in and clear …


Functional Significance Of The Hexosamine Biosynthesis Pathway In Pancreatic Cancer, Nikita Satish Sharma Dec 2019

Functional Significance Of The Hexosamine Biosynthesis Pathway In Pancreatic Cancer, Nikita Satish Sharma

Open Access Dissertations

Pancreatic cancer is a notoriously lethal disease. Late detection, lack of effective biomarkers, presence of a treatment refractory population of cells, an impermeable stroma, metastasis and tumor recurrence are some of the factors contributing to the dismissal 5-year survival rate of 8% for this disease. Hexosamine Biosynthesis Pathway (HBP) is a unique node in cancer metabolism. Its end product, UDP-GlcNAc is used by both tumor cells and the extracellular matrix component Hyaluronan for signaling, proliferation and metastasis of pancreatic cancer cells. While there have been reports examining the significance of HBP in individual factors contributing to tumor aggressiveness, a comprehensive …


Food Preferences Among Children At Arcadia Elementary School, Laurel Lee Dec 2019

Food Preferences Among Children At Arcadia Elementary School, Laurel Lee

Community Based Research

My research, conducted from September through November of 2017, showed that the children preferred more processed foods and starches instead of healthier options such as fruits and vegetables, even when healthy options were available. According to the parents/caregivers surveyed, their children prefer to eat processed American meals. Parents/caregivers desired for their children to eat a variety of different foods including fruit, vegetables, proteins, and traditional Hispanic food. This study acknowledges that healthy meal options are available at schools, but there needs to be more research on how to best encourage students to take advantage of these nutritious choices in order …


Patient-Centered Education To Improve Health Outcomes Of Adult Jamaicans With Diabetes, Patricia Anderson Dec 2019

Patient-Centered Education To Improve Health Outcomes Of Adult Jamaicans With Diabetes, Patricia Anderson

DNP Qualifying Manuscripts

There is a 42% prevalence of diabetes among Jamaicans (Ministry of Health, Jamaica Health and Lifestyle Survey, 2018). The survey found that Jamaicans will continue to face challenges of diabetes and its complication as approximately four out of ten Jamaicans are unaware that they have diabetes, and thus delay receiving healthcare.

Limited health literacy is predominant among the diabetic Jamaican population and negatively affects health outcomes (Singh & Aiken, 2017). Jamaicans were found to have poor knowledge of diabetes; in particular, they had difficulty identifying clinical signs of hyper/hypoglycemia, the importance of examining eyes and feet for abnormalities, normal fasting …