Digital Commons Network^™

A Disaster Preparedness Focused Dnp: Meeting Real-Time National And Global Needs, Patricia Tooker, Kathleen Dee Ahern, Nancy Cherofsky

Biennial Convention (CONV)

This presentation will provide the participants with a description of a Disaster Preparedness Focused DNP curriculum. Courses as well as evaluative tools will be presented. The Integration of the AACN Doctoral Essentials with Criteria for Evaluation of Nurse Practitioner Programs will be demonstrated through student learning outcomes.

Sleep And Cognitive Function: Examining How Sleep Impacts Cognition In Older Adults Living With Hiv, Judy A. Frain

Biennial Convention (CONV)

Participants will learn how older adults living with HIV experience poor sleep despite effective use of antiretroviral therapy to control their HIV virus. The correlation between poor sleep and cognitive function will be examined and the detrimental effect this has on successfully aging while living with HIV will be discussed.

An Assessment Of The Role Of Florida Pharmacists In The Administration Of Inactivated Influenza Vaccine To Pregnant Women, Oluyemisi O. Falope

USF Tampa Graduate Theses and Dissertations

The influenza vaccine is a safe and effective vaccine in preventing influenza infection in the general population. The Centers for Disease Control (CDC) recommend that pregnant women receive influenza inactivated vaccine (IIV) due to the high morbidity and mortality associated with influenza infection in pregnant women. Despite the recommendation, the U.S. national influenza vaccine uptake rates among pregnant women continue to remain low. Studies have shown barriers to influenza vaccine uptake in pregnant women to include issues with access, unavailability of vaccine, and lack of time during prenatal visits. These barriers can be overcome using pharmacists because, among healthcare providers, …

Modeling Mastitis Reveals Relative Impact Of (A)Symptomatic Infectivity, O. Liota Weinbaum, Helen J. Wearing

Shared Knowledge Conference

Despite widespread compliance with control recommendations, chronic infectious disease remains problematic in animal agriculture. Efforts to disrupt transmission target symptomatic individuals, but disease persists at the population level. Staphylococcus aureus mastitis in dairy cows is a painful inflammation of the udder that reduces milk volume and quality. The popularly targeted transmission mechanism is contact between the milk of symptomatic cows and the udders of susceptible cows via milking equipment. A common control practice is to milk symptomatic cows last, known as the Milk Last Intervention (MLI). However, asymptomatic cows are also infectious. We suspect that they play an important role …

Clpc Affects The Intracellular Survival Capacity Of Staphylococcus Aureus In Non-Professional Phagocytic Cells, Gubesh Gunaratnam, Lorena Tuchscherr, Mohamed I. Elhawy, Ralph Bertram, Janina Eisenbeis, Christian Spengler, Thomas Tschernig, Bettina Löffler, Greg A. Somerville, Karin Jacobs, Mathias Herrmann, Markus Bischoff

School of Veterinary and Biomedical Sciences: Faculty Publications

Invasion and persistence of bacteria within host cells requires that they adapt to life in an intracellular environment. This adaptation induces bacterial stress through events such as phagocytosis and enhanced nutrient-restriction. During stress, bacteria synthesize a family of proteins known as heat shock proteins (HSPs) to facilitate adaptation and survival. Previously, we determined the Staphylococcus aureus HSP ClpC temporally alters bacterial metabolism and persistence. This led us to hypothesize that ClpC might alter intracellular survival. Inactivation of clpC in S. aureus strain DSM20231 significantly enhanced long-term intracellular survival in human epithelial (HaCaT) and endothelial (EA.hy926) cell lines, without markedly affecting …

The Lived Experience Of Critically Ill Patients In Isolation Rooms: Surviving Isolation, Sondos Eqylan, Reema Safadi

Biennial Convention (CONV)

Critically ill patients with infectious diseases have dramatically increased in prevalence over the last few years. Patients suffer physically, psychologically and socially during staying in isolation settings. This session focusing on the meaning of critically ill patients' isolation experiences, their concerns and needs, psychological conditions, and relationships with healthcare providers

Improving Clinician Behaviors And Patient Safety Outcomes Through Standardization Of A Pediatric Vaccine Administration Process, Monica Joan Gingell, Marianne L. Durham, Susan Corbridge

Biennial Convention (CONV)

While significant research has focused on the safety of childhood vaccines' intrinsic properties, little attention has been given to the complex and error-prone vaccine administration process. The purpose of this quality improvement project is to improve clinician knowledge of pediatric vaccines and safe administration behaviors leading to decreased error.

Nearly Complete Genome Sequences Of 17 Enterovirus D68 Strains From Kansas City, Missouri, 2018, Suman B. Pakala, Yi Tan, Ferdaus Hassan, Annie Mai, Robert H. Markowitz, Meghan H. Shilts, Seesandra V. Rajagopala, Rangaraj Selvarangan, Suman R. Das

Manuscripts, Articles, Book Chapters and Other Papers

Here, we report 17 nearly complete genome sequences of enterovirus D68 (EV-D68) isolated from Kansas City, MO, in 2018. Phylogenetic analysis suggests that these strains belong to subclade B3, similar to the ones that caused the 2016 epidemics in the United States but different from the 2014 outbreak B1 strains.

The Observer, Central Washington University

Student Newspaper

Student newspaper for Central Washington University for November 7-13, 2019. Vol. 114, No. 6.

Epidemiological Analysis Of Malaria Decrease In El Salvador From 1955 Until 2017, Tatiana I. Gardellini Guevara

USF Tampa Graduate Theses and Dissertations

The disease of malaria is complex, with clinical presentation that ranges from severe and complicated to mild and uncomplicated or even to asymptomatic malaria. A recent effort made by several world organizations has shown important advances in the effort to control and eradicate malaria. Following the general ordinance established by the trans-border organizations, each country has tried to define, according to their local geopolitical scenario, individual ¨road maps¨ to succeed in reducing the morbidity and mortality caused by malaria. Moreover, it is now accepted universally that these road maps need to be revised and appropriated in order to correct actions …

Refugees' Perceptions Of Primary Care: What Makes A Good Doctor's Visit?, Anne Mutitu, Bev Zabler, Jeana M. Holt

Patient Experience Journal

Redesigning primary care is a national priority, as the United States (US) struggles with issues of poor access, high cost, and suboptimal quality. Refugees are among the populations who suffer from America’s disjointed health care system, resulting in disproportionate health disparities. Although there are many studies on refugee health, few share refugees' perceptions of primary care. We asked local refugees who were seen for primary care services at a midwestern academic nurse-led clinic, what makes a good doctor's visit?  The clinic served as the hub of a federally funded refugee Community Centered Health Home (CCHH) pilot project. This qualitative study …

The Role Of Adaptive Immunity In Chronic Hypoxia-Induced Pulmonary Hypertension, Levi David Maston

Biomedical Sciences ETDs

Inflammation is a prominent pathologic feature in pulmonary arterial hypertension as demonstrated by pulmonary vascular infiltration of inflammatory cells, including T and B lymphocytes. However, the contribution of the adaptive immune system is not well characterized in pulmonary hypertension (PH) caused by chronic hypoxia (CH). Inflammatory cells, through various mechanisms, have the capability to increase pulmonary vascular resistance in various disease states. CD4⁺T cells have the potential to play a significant role in the disease process initiated by hypoxia. CD4⁺T cells are largely responsible for orchestrating downstream immune processes and are critical in focusing and amplifying …

Impact Of The Human Footprint On Anthropogenic Mortality Of North American Reptiles, Jacob E. Hill, Travis L. Devault, Jerrold L. Belant

United States Department of Agriculture Wildlife Services: Staff Publications

Human activities frequently result in reptile mortality, but how direct anthropogenic mortality compares to natural morality has not been thoroughly investigated. There has also been a limited examination of how anthropogenic reptile mortality changes as a function of the human footprint. We conducted a synthesis of causespecific North American reptile mortality studies based on telemetry, documenting 550 mortalities of known cause among 2461 monitored individuals in 57 studies. Overall 78% of mortality was the result of direct natural causes, whereas 22% was directly caused by humans. The single largest source of mortality was predation, accounting for 62% of mortality overall. …

Immune Gene Diversity And Populations Structure Of Reticulated Flatwoods Salamander (Ambystoma Bishopi), Steven Tyler Williams

LSU Master's Theses

Reticulated flatwoods salamander (Ambystoma bishopi) populations began decreasing dramatically in the late 1900s. Contemporary populations are small, isolated, and may be susceptible to inbreeding and reduced adaptive potential because of low genetic variation. Genetic variation at immune genes is especially important as it influences disease susceptibility and adaptation to emerging infectious pathogens, a central conservation concern for declining amphibians. Connectivity between isolated populations is also vital to maintain genetic diversity and avoid inbreeding. I collected tissue samples from across the extant range of this salamander to examine genetic variation and population structure in: immune genes broadly (immunome), the …

Molecules That Inhibit Efflux Pumps In Multi-Drug Resistant Bacteria And Uses Thereof, George W. Gokel, Michael R. Gokel, Saeedeh Negin, Mohit Patel

UMSL Patents

Methods and compositions are provided for increasing or enhancing the efficacy of antibiotics, such as by increasing antimicrobial activity, against a variety of microbes by co-administration with synthetic amphiphiles, including lariat ethers and hydraphiles. Methods and compositions for overcoming antibiotic resistance are also provided.

For the most up-to-date information about these patents, including the availability of Certificates of Correction, be sure to check the United States Patent and Trademark Office's free, publicly accessible database: Patent Public Search https://ppubs.uspto.gov/pubwebapp/static/pages/landing.html

Uab's 1917 Clinic To Find New Home In Lakeview, Alicia Rohan

Browse All News

No abstract provided.

A Deda Family Membrane Protein Is Required For Burkholderia Thailandensis Colistin Resistance, Pradip R. Panta, Sujeet Kumar, Caroline F. Stafford, Caitlin E. Billiot, Martin V. Douglass, Carmen M. Herrera, M. Stephen Trent, William T. Doerrler

Faculty Publications

© Copyright © 2019 Panta, Kumar, Stafford, Billiot, Douglass, Herrera, Trent and Doerrler. Colistin is a “last resort” antibiotic for treatment of infections caused by some multidrug resistant Gram-negative bacterial pathogens. Resistance to colistin varies between bacterial species. Some Gram-negative bacteria such as Burkholderia spp. are intrinsically resistant to very high levels of colistin with minimal inhibitory concentrations (MIC) often above 0.5 mg/ml. We have previously shown DedA family proteins YqjA and YghB are conserved membrane transporters required for alkaline tolerance and resistance to several classes of dyes and antibiotics in Escherichia coli. Here, we show that a DedA family …

Atm Deficiency Accelerates Dna Damage, Telomere Erosion, And Premature T Cell Aging In Hiv-Infected Individuals On Antiretroviral Therapy, Juan Zhao, Lam Ngoc Nguyen, Lam Nhat Nguyen, Xindi Dang, Dechao Cao, Sushant Khanal, Madison Schank, Bal Krishna Chand Thakuri, Stella C. Ogbu, Zheng D. Morrison, Xiao Y. Wu, Zhengke Li, Yue Zou, Mohamed El Gazzar, Shunbin Ning, Ling Wang, Jonathan P. Moorman, Zhi Q. Yao

ETSU Faculty Works

HIV infection leads to a phenomenon of inflammaging, in which chronic inflammation induces an immune aged phenotype, even in individuals on combined antiretroviral therapy (cART) with undetectable viremia. In this study, we investigated T cell homeostasis and telomeric DNA damage and repair machineries in cART-controlled HIV patients at risk for inflammaging. We found a significant depletion of CD4 T cells, which was inversely correlated with the cell apoptosis in virus-suppressed HIV subjects compared to age-matched healthy subjects (HS). In addition, HIV CD4 T cells were prone to DNA damage that extended to chromosome ends—telomeres, leading to accelerated telomere erosion—a hallmark …

The Implementation Of An Open Source Electronic Medical Record At A Faith-Based Community Clinic, Gabri Warren

Graduate Theses, Dissertations, and Capstones

Faith-based nursing and healthcare is increasingly gaining popularity as the industry looks to minimize costs and improve health outcomes. Historically, qualitative studies have not shown the extent to which individuals and communities are impacted by health initiatives initiated by faith institutions. Healthcare technology can help support the specialty by providing increased quantity and quality data to analyze. Traditional, proprietary EMRs are too costly; however, open source systems offer a low cost, and easily modifiable option to non-profit, or smaller organizations. The data collected by an open source system allows organizations to improve the care that patients receive, and helps guide …

Comparing The Effect Of Community Engagement On The Impact Of Water Filter Usage, Brooks N. Holt, Kim L. Larson

Biennial Convention (CONV)

The research team will conduct a household survey in summer 2019 to determine how community collaboration can influence the impact and use of household water filters on family health outcomes.

Effectiveness Of The E-Nursus Children Intervention In The Training Of Nursing Students, Cristina Álvarez-García, Carmen Álvarez-Nieto, Janet Kelsey, Rachel Carter, Sebastián Sanz-Martos, Isabel M. López-Medina

School of Nursing and Midwifery

The paediatric population is the most vulnerable to exposure to environmental risk factors. Institutions of higher education have to equip nursing students with the attitudes, knowledge, and skills to respond to this using blended learning. The aim of this study was to evaluate the effect of e-NurSus Children intervention on student nurses’ attitudes, knowledge, and skills. A quasi-experimental study of time series was designed using pre and post educational intervention evaluation in 2018. The participants were nursing students (N = 267) from Spain (n = 110) and the United Kingdom (n = 157). Three instruments were used: the Sustainability Attitudes …

Indigenous Women And Research: Global Conversations On Indigeneity, Rights, And Education, Elizabeth Sumida Huaman, Tessie Naranjo

International Journal of Human Rights Education

No abstract provided.

Developments For The Treatment Of Invasive Infections Due To Multidrug-Resistant Acinetobacter Baumannii, David Laurent, Richard Drew, Dustin Wilson

The University of Louisville Journal of Respiratory Infections

Acinetobacter baumannii is a significant pathogen in healthcare settings (specifically prominent in healthcare- and ventilator-associated pneumonia) due primarily to its virulence and resistance to a wide variety of antimicrobial drug classes, including carbapenems (CRAB). Existing therapies (notably polymyxins, minocycline, tigecycline, amikacin, and sulbactam) often result in suboptimal tissue concentrations, high rates of toxicity, and increasing rates of resistance. Although utilizing combinations of antibiotics (specifically those containing colistin) have been employed, results have been mixed, and control trials are lacking. Eravacycline is a novel tetracycline with an improved pharmacokinetic profile and more potent activity against A. baumannii relative to tigecycline. Cefiderocol …

Jcph Presentations At The American Public Health Association Annual Conference 2019

JCPH at APHA 2019

No abstract provided.

“It’S Always A Part Of You”: The Connection Between Sacred Spaces And Indigenous/Aboriginal Health, Danelle Cooper, Treena Delormier, Maile Taualii

International Journal of Human Rights Education

Since colonization, Indigenous/Aboriginal Peoples (IAP) have fought for their inherent rights to follow their ways of life on their traditional territories. One continuing battle is the protection of sacred spaces. Sacred spaces are places recognized by IAP as deeply spiritually and powerful. Relationships to sacred spaces sustain spiritual connections integral to our concepts of holistic health/well-being and are vital for cultural integrity. Though all of the natural world is sacred to IAP, the particular cultural and spiritual significance of sacred spaces and impact on health merits attention. Drawing from qualitative research, this article investigates IAP’s perspectives and experiences regarding the …

The Importance Of Integrating “Biosecurity Policies” In The Peruvian Maritime Sector, Christian Velarde Morillas

World Maritime University Dissertations

No abstract provided.

The Implementation Of The International Convention For The Control And Management Of Ships’ Ballast Water And Sediments, 2004 In China : Challenges And Prospects, Shuyan Ji

World Maritime University Dissertations

No abstract provided.

Finding The Evidence: Search And Reporting Methodologies For Systematic Reviews And Meta-Analyses, Linda Östlundh

Presentations

No abstract provided.

Bismarck To No Effect: Fertility Decline And The Introduction Of Social Insurance In Prussia, Timothy W. Guinnane, Jochen Streb

Discussion Papers

Economists have long argued that introducing social insurance will reduce fertility. The hypothesis relies on standard models: if children are desirable in part because they provide security in case of disability or old age, then state programs that provide insurance against these events should induce couples to substitute away from children in the allocation of wealth. We test this claim using the introduction of social insurance in Germany in the 1880s and 1890s. Bismarck’s social-insurance system provided health insurance, workplace-accident insurance, and old age pensions to a majority of the working population. The German case appeals because the social insurance …

Total Phenolic And Flavonoid Content And Biological Activities Of Extracts And Isolated Compounds Of Cytisus Villosus Pourr., Farida Larit, Francisco León, Samira Benyahia, Stephen J. Cutler

Faculty and Student Publications

© 2019 by the authors. Kadsura coccinea (Lem.) A.C. Smith is an evergreen, woody climbing plant that is widely distributed throughout southwest mainland China. Extracts of this plant are used in traditional Chinese medicine (TCM) for the treatment of various diseases, like cancer and dermatosis, and as an anodyne to relieve pain, while the leaves are used to treat eczema. In the current study, the toxicity of essential oil from its stem (EOKC) was studied against two strains of bed bugs (Cimex lectularius). Essential oil from the plant was obtained by hydrodistillation and analyzed by GC/MS. The major compound identified …