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Goals, Outcomes, And Efficacy Of Music Programming In Prisons, Liam Byrnes 18

Honor Scholar Theses

No abstract provided.

The Ethics Of Single-Use Plastics, Kiara Goodwine '19

Honor Scholar Theses

No abstract provided.

Unpacking The Opioid Epidemic: Intervention Methods And Effects On Women And Children, Olivia Miller 19

Honor Scholar Theses

No abstract provided.

Inspire : Vol 2, Issue 4, Department Of Medicine

INSPIRE – Department of Medicine Archives

Content

• Message From The Chair
• The Story of a Stroke Champion; Professor Ayeesha Kamran Kamal
• Department of Medicine Appreciation Evening
• Conquering Hepatitis via Micro-elimination (CHIME) Grant
• Department of Medicine
• Pilot Project;
• Electronic Attendance for Grand Rounds & Meetings
• Potential to sync with One45
• Say Good-Bye to Manual Attendance Sheets
• Department of Medicine at National and International Forums Featured Faculty Profile Dr. Syed Ahsan; “ Humility and patience are the hallmarks of a good leader.”
• What Are Academics Around the World Reading This Month?

Performance Of A Novel Low-Cost, Instrument-Free Plasma Separation Device For Hiv Viral Load Quantification And Determination Of Treatment Failure In People Living With Hiv In Malaysia: A Diagnostic Accuracy Study, Minh D. Pham, Berhan A. Haile, Iskandar Azwa, Adeeba Kamarulzaman, Nishaan Raman, Alireza Saeidi, Maria Kahar Bador, Margaret Tan, Jiawei Zhu, Yi Feng, Julian H. Elliott, Mary L. Garcia, Fan Li, Suzanne M. Crowe, Stanley Luchters, David A. Anderson

Population Health, East Africa

HIV viral load (VL) testing is the recommended method for monitoring the response of people living with HIV and receiving antiretroviral therapy (ART). The availability of standard plasma VL testing in low- and middle-income countries (LMICs), and access to this testing, are limited by the need to use fresh plasma. Good specimen collection methods for HIV VL testing that are applicable to resource-constrained settings are needed. We assessed the diagnostic performance of the filtered dried plasma spot (FDPS), created using the newly developed, instrument-free VLPlasma device, in identifying treatment failure at a VL threshold of 1,000 copies/ml in fresh plasma. …

Humanitarian Assistance In Protracted Emergencies: Rethinking The Role Of Food Aid In Adjumani, Victoria Puglia

Independent Study Project (ISP) Collection

Humanitarian food assistance is incredibly susceptible to funding cuts, which reduces the quantity of food available to refugees. If refugees depend solely on food aid for survival, the implication of reductions is increased food insecurity at a household level. The Government of Uganda champions a self-reliance strategy that has failed to support refugees to the desired extent, especially when food rations are low. This study aims to assess the impact of humanitarian food assistance on the socioeconomic structures of refugee settlements in Adjumani, Uganda to understand the consequences of unstable food aid. The research was conducted over a four-week period. …

The Intersections Of Health And Wealth: Socioeconomic Status, Frailty, And Mortality In Industrial England, Samantha Lee Yaussy

Theses and Dissertations

Socioeconomic status (SES) is considered one of the most powerful predictors of mortality today. However, studies of health in living populations and bioarchaeological studies of health in the past often oversimplify the connection between SES and mortality and overlook heterogeneity in frailty within a population and the potential for multiple types of marginalization to be layered within a single individual. This dissertation project uses skeletal samples to examine the interactions of SES, demographic characteristics (e.g., age and sex), exposure to physiological stressors, and mortality in the context of industrialization in 18th- and 19th-century England. Skeletal data from four industrial-era cemeteries …

Tool Migration: A Framework To Study The Cross-Disciplinary Use Of Mathematical Constructs In Science, Chia-Hua Lin

Theses and Dissertations

This dissertation is concerned with the scientific practice in which a mathematical construct that was originally developed to study a particular subject matter subsequently used in other disciplines or sub-disciplines for a different subject matter, a phenomenon that I call ‘tool migration.’ I argue that tool migration can be ‘epistemically risky.’ Specifically, uprooting a research tool from one disciplinary context and re-situating it for use in another can change how the tool is applied; whatever has made the tool useful and reliable in the first place may not have stayed the same in the new context. Using the migrations of …

Role Of Resources For Care In Improving Care Behaviors, Children’S Nutritional Status And Early Childhood Development In Low- And Middle-Income Countries, Sulochana Basnet

Theses and Dissertations

Poor child growth and suboptimal early childhood development are global health problems. Provision of appropriate care may help to achieve optimum child growth and development. Maternal resources for care such as education, knowledge, health, autonomy, reasonable workload, and social support may be needed to provide appropriate care behaviors, and improve children’s nutritional status, and early childhood development. The overall goal of this research was to understand the role of resources for care in improving care behaviors, child nutritional status, and early childhood development. The baseline Alive & Thrive household surveys from Bangladesh, Vietnam, and Ethiopia were used. We examined the …

The Development Of A Health, Safety And Environment Management System For An Integrated Gender Separated Campus In The Middle East Region – A Case Study, Fatima Sbait Salmeen Al Wahshi

Biology Theses

In recent years, concerns regarding health, safety, and environmental issues increased. This led to the development of integrated Health, Safety and Environment (HSE) Management Systems in many organizations, including universities. The study of the current HSE management system of the United Arab Emirates University (UAEU) has been conducted as a typical National university in the Middle East Region with the added unique feature of a large integrated campus with gender separation. Emphasis has been given to the E-shared laboratories of the UAEU as the interface between the two sides (male/female) of the campus. The E-shared laboratories incorporate most of the …

Rare Variant Of Guillain-Barré Syndrome After Chikungunya Viral Fever, Sajid Hameed, Sara Khan

Section of Neurology

Chikungunya (CHIK) viral fever is a self-limiting illness that presents with severe debilitating arthralgia, myalgia, fever and rash. Neurological complications are rare. We present a case of a 36-year-old woman who presented with acute onset progressive difficulty swallowing and left arm weakness. She was diagnosed with CHIK viral fever 4 weeks prior to admission. After investigations, she was diagnosed with a pharyngeal-cervical-brachial variant of Guillain-Barré syndrome. In hospital, she required ventilator support. Her condition improved after five sessions of intravenous immunoglobulin with almost complete resolution within 6 months of symptom onset. With frequent CHIK outbreaks, the neurological complications are increasingly …

The Makes Of A Turnaround Church : Common Patterns And Contributing Factors, Edgar Bazan

ATS Dissertations

No abstract provided.

Regression For Pooled Testing Data With Biomedical Applications, Juexin Lin

Theses and Dissertations

Since first introduced by Dorfman in 1943, pooled testing has been widely used as a cost and time effective testing protocol in the variety of applications. This dis- sertation consists of three projects that reveal the use of pooling techniques in the disease prevention from the perspective of regression. For disease monitoring and control, individual covariates information are often of practical interest and yield meaningful interpretations. It is natural to model the outcome of interest, which can be either a disease status (binary) or a biomarker concentration index (continuous), with individual-specific covariates through a regression analysis. Chapter 2 focuses on …

The Design And Physical Properties Of An Optimized Chitosan Hydrogel For Potential Use In Endodontics, Hunter Housley

Master's Theses (2009 -)

Introduction: The aim of this study was to synthesize an optimized chitosan/carbon dot hydrogel and measure its effects on the proliferation of dental pulp stem cells. Methods: 1.5% w/v chitosan hydrogel samples were fabricated with 300 mg/ml aqueous β-glycerol phosphate (β-GP) to create an optimized chitosan with a gelation onset temperature below 37°C. Spermidine-functionalized carbon dots (CDs) were added to test groups in concentrations of 25 µg/ml and 50 µg/ml. Complex shear viscosity of the prepared hydrogel samples was evaluated with a Kinexus pro+ shear rheometer (Malvern Panalytical). Samples were evaluated for cellular proliferation with dental pulp stem cells at …

Sand Fly–Associated Phlebovirus With Evidence Of Neutralizing Antibodies In Humans, Kenya, David P. Tchouassi, Marco Marklewitz, Edith Chepkorir, Florian Zirkel, Sheila B. Agha, Caroline C. Tigoi, Edith Koskei, Christian Drosten, Christian Borgemeister, Baldwyn Torto, Sandra Junglen, Rosemary Sang

All Peer-Reviewed Publications

We describe a novel virus, designated Ntepes virus (NPV), isolated from sand flies in Kenya. NPV has the characteristic phlebovirus trisegmented genome architecture and is related to, but distinct from, Gabek Forest phlebovirus. Diverse cell cultures derived from wildlife, livestock, and humans were susceptible to NPV, with pronounced permissiveness in swine and rodent cells. NPV infection of newborn mice caused rapid and fatal illness. Permissiveness for NPV replication in sand fly cells, but not mosquito cells, suggests a vector-specific adaptation. Specific neutralizing antibodies were found in 13.9% (26/187) of human serum samples taken at the site of isolation of NPV …

Perspectives On Social Support And Stigma In Prep-Related Care Among Gay And Bisexual Men On Prep: A Qualitative Investigation, Juan Pablo Zapata

Master's Theses (2009 -)

Men who have sex with men (MSM) are disproportionately impacted by HIV. Today, one of the most effective and innovative HIV prevention tools available is pre-exposure prophylaxis (PrEP). Despite its remarkable effectiveness at preventing HIV transmission, awareness and uptake of PrEP as a prevention strategy has been slow to take hold. As evidenced in previous literature, experiences of stigma have been found to negatively impact psychological and physical stress, and medication adherence. Social support has been found to buffer against some of these psychological and behavioral responses. This study explored the psychosocial dimensions of PrEP use among MSM to promote …

The Impact Of Concomitant Empiric Cefepime On Patient Outcomes Of Methicillin-Resistant Staphylococcus Aureus Bloodstream Infections Treated With Vancomycin, Evan J. Zasowski, Trang D. Trinh, Safana M. Atwan, Marina Merzlyakova, Abdalhamid M. Langf, Sahil Bhatia, Michael J. Rybak

Faculty Publications & Research of the TUC College of Pharmacy

Background: Data suggest that vancomycin + β-lactam combinations improve clearance of methicillin-resistant Staphylococcus aureus(MRSA) bloodstream infections (BSIs). However, it is unclear which specific β-lactams confer benefit. This analysis evaluates the impact of concomitant empiric cefepime on outcomes of MRSA BSIs treated with vancomycin.

Methods: Retrospective cohort study of adults with MRSA BSI from 2006 to 2017. Vancomycin + cefepime therapy was defined as ≥24 hours of cefepime during the first 72 hours of vancomycin. The primary outcome was microbiologic failure, defined as BSI duration ≥7 days and/or 60-day recurrence. Multivariable logistic regression was used to evaluate the association between …

Z4, A Slow Puncture: An Autoethnographic Exploration Of Language, Embodiment, And Meaning-Making, Charlotte Rose Samuels

Independent Study Project (ISP) Collection

In my ISP, I explored language as it relates to the ways in which people living in Cato Manor make sense of HIV/AIDS in their community. With 7.1-7.2 million people living with HIV (PLWHIV) in South Africa, individuals across the country are either infected or affected by illness. KwaZulu-Natal (KZN), the province with the highest rate of HIV, is also the province that was surveyed with the disproportionately highest internal stigma rates for PLWHIV. High prevalence of HIV, particularly in KZN, calls for a constant contextualization of life in the presence of illness.

Throughout the world, metaphor and symbolism is …

From The American People: An Autoethnographic Exploration Of South African Ngos' Perceptions Of Pepfar, Antonia Asher

Independent Study Project (ISP) Collection

The aim of this research was to understand what the ideal partnership would be between United States (US) governmental aid agencies and South African non-governmental organizations (NGOs), specifically concerning HIV/AIDS programs funded by the US President’s Emergency Plan for AIDS Relief (PEPFAR), from the perspective of NGOs. PEPFAR is the largest relief fund for a single disease; thus, I additionally sought to deeply reflect upon myself as a US citizen in South Africa, a country that has received trillions of dollars from taxpayers such as myself.

To accomplish this, I interviewed NGO staff about the nature of current partnerships, outcomes …

Women In Conservation: A Study Of Effective Community-Based Conservation And The Empowerment Of Women In Tanzania, Ruby Krietzman

Independent Study Project (ISP) Collection

The subject of this study is women involved in Community-Based Conservation (CBC) from areas surrounding Lake Manyara National Park, Ngorongoro Conservation Area, and Mount Kilimanjaro National Park. CBC is a participatory process between people and organizations who have responsibilities affecting conservation. Communities surrounding protected conservation areas tend to experience high levels of poverty and marginalization due to exclusive conservation policies and the lack of co-management principles. Although tourism revenue is abundant in these locations, the benefits rarely impact local community members that disproportionately experience the effects of conservation. This is especially true for women who hold the responsibilities of collecting …

Characterizing Systems Of Reporting And Mitigating Anthrax Outbreaks Near Mto Wa Mbu, Monduli District, Tanzania, Megan Levy

Independent Study Project (ISP) Collection

Northern Tanzania has experienced several anthrax outbreaks in the recent past. In Monduli district, an outbreak in 2016 prompted an organization of district officials to create an updated outbreak response action plan. The pastoralist community is often affected by these outbreaks due to their frequent direct contact with cattle and herds’ proximity to wild species potentially affected by the disease. This characterization of the existing systems of reporting and mitigating anthrax outbreaks was accomplished through structured interviews with ward and village officers, local veterinarians, and members of the pastoralist community in Monduli district near Mto wa Mbu. The purpose of …

Vaccine Hesitancy In The United States And Switzerland, Anna E. Lunderberg

Independent Study Project (ISP) Collection

Vaccine hesitancy (VH), or the reluctance or refusal to participate in vaccination programs, is a complex phenomenon with far-reaching impacts on society. VH can impact vaccine uptake and facilitate subsequent outbreaks, as seen with the case of measles. Perceptions of vaccination are similar in the United States and Switzerland, and misinformation in each country contributed to VH through impaired parental risk-benefit analysis; parental analysis and subsequent VH is associated with both anti-vaccination messages gaining prominence and a decrease in the public perception of the health risk from vaccine-preventable diseases (VPDs). There are many proposed strategies for addressing VH on both …

Quality Over Quantity: A Comparative Analysis Of The Quality Measures And Performance Between Switzerland And The United States, Lexi Farina

Independent Study Project (ISP) Collection

Even in the best health systems, poor quality of care continues to cause harm to patients and prevent them from receiving the best treatment possible. Thus, it is important to record and report quality of care measures because they can help inform policy changes and improve performance. In this paper, a comparative analysis between the United States and Switzerland is conducted to understand the process for defining and assessing quality indicators in each country as well as compare their quality of care performance results. The methods for this study include a literature review of relevant background information relating to quality …

Nationalizing Services For The Trans-National: How Sub-Saharan Migrants Navigate Healthcare Access In Tunisia, Batoul Hasan

Independent Study Project (ISP) Collection

The right to human health and the resources that empower this state is an entitlement recognized under international law. With the circumstances surrounding their journeys, migrants face increased risks and vulnerabilities that necessitate social protections. Nations of reception, due to exclusionary policies or lack of capacity, may fail to guarantee these protections. This study investigates how this phenomenon unfolds in Tunisia, a middle-income nation undergoing a host of political and economic changes, but one that’s nonetheless become an alluring destination for migrants, specifically those from sub-Saharan African nations. The analysis proceeds from an assessment of the public health situation in …

Pasantía En Red Oss: Más Que Una Clínica, Saad Ehsan

Independent Study Project (ISP) Collection

RED OSS es una organización en Conchalí, Santiago que provee pruebas rápidas de VIH y actualiza otras pruebas para ETS en una manera gratuita desde 1991. Durante mi pasantía, investigué como una organización disminuye las desigualdades de salud. También aprendí sobre el financiamiento de RED OSS, las pruebas rápidas y el nicho de RED OSS en un país con un sistema pública. Utilicé observaciones y entrevistas para estudiar la clínica. Tuve oportunidades para asistir los talleres para prevenir homofobia y ver las consejerías con un voluntario. También actualicé el sitio web para reflejar los servicios que RED OSS ofrece. En …

Social Support And Discrimination: The Experiences Of Recovering Heroin Addicts In Kunming, China, Phoebe Li

Independent Study Project (ISP) Collection

Opioids have had a long, complex position in Chinese society, dating all the way back to the Ming dynasty. In 1949, 5% of the overall Chinese population and 25% of the population in Yunnan smoked opium regularly, which led to societal collapse and economic downturn. Since then, the Chinese government has used many different methods to attempt to control drug use and trafficking, including registering all users, executing traffickers, and using Compulsory Rehabilitation Centers. Starting in 2008, the government switched to a harm reduction approach and began to invest in methadone clinics, community support groups, and needle exchange programs. Because …

Is Technology The Key To Prevention Of Falls Among The Elderly In Rapidly Aging Societies? A Case Study Of Kunming, China, Phoebe Kiburi

Independent Study Project (ISP) Collection

As the aging society rapidly becomes more dominant in the world, there is a pressing need for different stakeholders to tend to the needs of the aging sufficiently. This is crucial in ensuring the robustness of the healthcare system as a whole; given that it can only be as strong as its weakest link. This study focuses on one of the areas of need of the ageing society: fall prevention.

Numerous studies have been done on interventions by the government, private entities, elderly people and their caregivers to prevent occurrence and recurrence of falls. However, most of these have been …

Health On The Move: Health-Seeking Behavior Of Changpa Nomads In Ladakh, India, Maya Lubeck-Schricker

Independent Study Project (ISP) Collection

The goal of this study is to understand the health-seeking behavior of Changpa nomads in the Changthang region of Ladakh, India including what health issues these communities face, what they do when they fall sick, any preventative health behavior they implement, as well as the health infrastructure available to them. Very little literature exists on the health seeking-behavior of people in South Asia in general, much less among nondominant lifestyles such as that of nomadic or semi-nomadic people. As such, this research hopes to move towards closing that knowledge gap by conducting and analyzing 26 in depth semi-structured interviews and …

Murine Typhus Presenting With Acute Psychosis And Disseminated Intravascular Coagulation: A Case Report, Abdullah M. Pervaiz, Rabail Tariq, Salman A. Bangash, Yasir Lal

School of Medicine Publications

Murine typhus is an endemic infectious disease caused by Rickettsia typhi and is transmitted by fleas. It typically causes a mild illness with symptoms of fever, rash, headache, chills, and non-specific gastrointestinal complaints. However, there have been no reported cases in the literature of murine typhus infection causing symptoms of acute psychosis and disseminated intravascular coagulation (DIC).

A 30-year-old female with a history of gastric bypass and chronic pain syndrome presented to the emergency department with altered mental state and fever. She developed vivid visual hallucinations, DIC, and hypoxia with pulmonary opacities, ultimately requiring intubation. Magnetic resonance imaging (MRI) showed …

Genetic Structure Of The Painted Bunting And Its Implications For Conservation Of Migratory Populations, Andrea Contina, Jose L. Alcantara, Eli S. Bridge, Jeremy D. Ross, William F. Oakley, Jeffrey F. Kelly, Kristen Ruegg

School of Integrative Biological & Chemical Sciences Faculty Publications

The Painted Bunting Passerina ciris is a Neotropical songbird which breeds primarily in the USA during the summer and migrates to Mexico, Central America, southern Florida and the Caribbean over the winter. Male Painted Buntings are brightly coloured, which makes them highly sought after as pets, particularly in Mexico, Central America and Europe. We used short sequence repeats (microsatellite DNA) to investigate the population genetic structure of the Painted Bunting and its implications in conservation management of migratory populations. We found a detectable level of population differentiation as revealed by pairwise FST and RST comparisons and Bayesian clustering …