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Risk Factors And Prevalence Of Sti Symptoms In Rural Mayan Villages In Guatemala, Mabel Ezeonwu, Heidi A. Stecher, Lauren Smith, Ronald Carrick

International Nursing Research Congress (INRC)

This study investigates the prevalence of sexually transmitted infections (STIs) in rural Guatemalan villages as well as the risk factors that predispose the population particularly women to STIs.

Predictors Of Multiple Sexual Partners Among Youth Aged 15 To 24 In Gambia, Ismaila Sonko

International Nursing Research Congress (INRC)

In order to mitigate the spread of sexually transmitted infections (STIs) and HIV/AIDS that affects many young men and women especially among countries in Sub-Saharan Africa, having multiple sexual partners (MSPs) is one of the key factors that has been predicted to contribute to it's spread.

Improving Hiv Treatment Program Adherence In An Ethnically Diverse Urban Clinic, Nadine A. Brown Farr

International Nursing Research Congress (INRC)

Advances in research and treatment modalities have greatly increased the lifespan and outcomes for individuals living with HIV. However, the emotional challenges and social stigma remain barriers to treatment. This project review steps implemented in three urban California clinics to help counteract these issues.

Hiv/Sti And Intimate Partner Violence Prevention For Latinos, Nilda (Nena) Peragallo Montano, Natalia Villegas, Rosina Cianelli, Madeline Fernandez

International Nursing Research Congress (INRC)

The purpose of this study is to assess risk factors and to identify prevention strategies for Latino men and women between 18 and 50 years old in the U.S. This presentation is aimed at professionals interested in HIV prevention strategies for Latinos/or and the development of culturally-specific interventions.

Typha (Cattail) Invasion In North American Wetlands: Biology, Regional Problems, Impacts, Ecosystem Services, And Management, Sheel Bansal, Shane C. Lishawa, Sue Newman, Brian A. Tangen, Douglas Wilcox, Dennis Albert, Michael J. Anteau, Michael J. Chimney, Ryann L. Cressey, Edward Dekeyser, Kenneth J. Elgersma, Sarah A. Finkelstein, Joanna Freeland, Richard Grosshans, Page E. Klug, Daniel J. Larkin, Beth A. Lawrence, George Linz, Joy Marburger, Gregory Noe, Clint Otto, Nicholas Reo, Jennifer Richards, Curtis Richardson, Leroy Rodgers, Amy J. Schrank, Dan Svedarsky, Steven Travis, Nancy Tuchman, Lisamarie Windham-Myers

United States Department of Agriculture Wildlife Services: Staff Publications

Typha is an iconic wetland plant found worldwide. Hybridization and anthropogenic disturbances have resulted in large increases in Typha abundance in wetland ecosystems throughout North America at a cost to native floral and faunal biodiversity. As demonstrated by three regional case studies, Typha is capable of rapidly colonizing habitats and forming monodominant vegetation stands due to traits such as robust size, rapid growth rate, and rhizomatic expansion. Increased nutrient inputs into wetlands and altered hydrologic regimes are among the principal anthropogenic drivers of Typha invasion. Typha is associated with a wide range of negative ecological impacts to wetland and agricultural …

The Effect Of Immunomoduline And Phytin Compounds On Lipid Peroxidation Induced At Toxic Experimental Hepatitis, K.T. Mirzaahmedova

Central Asian Journal of Pediatrics

The influence of immunomodulin, phytin compounds as phytin-C and cobalt phytate and their combinations on lipid peroxidation processes in experimental toxic hepatitis in rats was studied. It was found that the studied drugs in carbon tetrachloride poisoning had a unidirectional antioxidant effect. Combined administration of immunomodulin with phytin compounds increased antioxidant activity.

The Weekly Challenger, June 20, 2019, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The June 20, 2019, issue of The Weekly Challenger.

Open Textbook Project [Poster], Sue Ann Gardner

University of Nebraska-Lincoln Libraries: Presentations

Details of a porject undertaken to collaboratively write and produce an open access parasitology textbook for undergraduate and graduate students. The book will be published by Zea Books at the University of Nebraska-Lincoln in 2020 and be available in English and Spanish both online and print-on-demand through lulu.com.

Co-Executive Editors: Scott L. Gardner and Sue Ann Gardner, University of Nebraska-Lincoln. Publisher: Paul Royster/Zea Books, University of Nebraska-Lincoln. Spanish Translator: Yoanna Esquivel Greenwood, University of Nebraska-Lincoln. Project Coordinator: Sue Ann Gardner.

Project website: Concepts in Animal Parasitology.

Sequence Variability In The Nramp1 Geneamong Indigenous And Exotic Chicken Types, Abazuh Uchenna Desmond, Adekoya Khalid Olajide, Oboh Bola Olufunmilayo

Makara Journal of Science

The natural resistance-associated macrophage protein 1 (NRAMP1) gene in chickens, which exists on chromosome 7, is thought to play a significant role in disease resistance. Variations in this gene have been documented and have played crucial roles in the variations in the resistance and/or susceptibility that is expressed by individuals and different groups of animal species. In this study, the NRAMP1 gene was studied for single nucleotide polymorphism (SNP) variability between indigenous and exotic chicken breeds. The gene was amplified using the polymerase chain reaction (PCR) method and sequenced and analyzed. Six SNPs, both synonymous and non-synonymous (C3700T, G3702C, A3712C, …

The Effects Of Helicobacter Pylori On Cognition: A Report, Kenric Gordon, Thomas Petersen, Dawson Hedges

Journal of Undergraduate Research

Last year we applied for an ORCA grant for our study of the effects of Helicobacter Pylori on Cognition. Helicobacter Pylori is a bacterium that causes ulcers in the stomach. It has also been implied to cause decreased cognitive functioning. (Berrett, Erickson, Brown, Hedges, 2016) Due to this, it is necessary to discover how Helicobacter Pylori effects cognition and how we can tell through EEG whether someone has Helicobacter Pylori.

"We Didn't Know": An Examination Of Health And Nutrition Knowledge, Behaviors And Clinical Risk Factors To Guide A Pilot Health Education Intervention For Refugees From Burma, Elizabeth B. Smith, Lauren R. Sastre

Journal of Refugee & Global Health

No abstract provided.

Predicting The Future: Parental Progeny Investment In Response To Environmental Stress Cues, Leah Gulyas, Jennifer R. Powell

Biology Faculty Publications

Environmental stressors can severely limit the ability of an organism to reproduce as lifespan is decreased and resources are shifted away from reproduction to survival. Although this is often detrimental to the organism’s reproductive fitness, certain other reproductive stress responses may mitigate this effect by increasing the likelihood of progeny survival in the F1 and subsequent generations. Here we review three means by which these progeny may be conferred a competitive edge as a result of stress encountered in the parental generation: heritable epigenetic modifications to nucleotides and histones, simple maternal investments of cytosolic components, and the partially overlapping phenomenon …

The Genesis Of The “Brain-Eating” Amoeba, Alan L. Gillen, Jonathan Augusta, Kurt Schneckenburger

Faculty Publications and Presentations

The Creator made all creatures, including amoebas, with variation and plasticity in their genome for global differences of climate, terrain, and environment. God made all creatures to multiply and fill the earth. Diversification and speciation from the original kind would be normal even in a perfect world. Naegleria fowleri is a global amoeba pathogen that is the causative agent of primary amoebic meningoencephalitis (PAM), thus termed “brain-eating.” Many people are evidently exposed, based upon antibody levels, to this amoeba while swimming in warm waters. Only a small percentage succumb to the germ, but once invasion happens, only about 1% survive. …

Table Of Contents: The Medicine Forum Volume 20, 2018-2019

The Medicine Forum

Clinical Images

Case Reports

• Cardiology
• Endocrinology
• Gastroenterology and Hepatology
• Hematology and Oncology
• Infectious Disease
• Pulmonary Medicine
• Rheumatology

Original Article

Editorial

Literature Review

Creative Writing

The Medicine Forum: Volume 20

The Medicine Forum

The Journal of Thomas Jefferson University Hospital - Department of Internal Medicine, Volume 20, 2018-2019

TABLE OF CONTENTS

Clinical Images

Case Reports

• Cardiology
• Endocrinology
• Gastroenterology and Hepatology
• Hematology and Oncology
• Infectious Disease
• Pulmonary Medicine
• Rheumatology

Original Article

Editorial

Literature Review

Creative Writing

N2n N4-Disubstituted Quinazoline-2,4-Diamines And Uses Thereof, Roman Manetsch, Kurt S. Van Horn, Whittney Burda, Lindsey N. Shaw, Renee Fleeman, Megan Barber, David Lawrence Flanigan

USF Patents

Described herein are quinazoline-based compounds and formulations thereof. In some embodiments, the compounds and/or formulations thereof can be effective to inhibit and/or kill A. baumannii. Also described herein are methods of treating a subject in need thereof by administering to the subject in need thereof a quinazoline-based compound and/or formulation thereof to the subject in need thereof.

Repurposing Of Glycine-Rich Proteins In Abiotic And Biotic Stresses In The Lone-Star Tick (Amblyomma Americanum), Rebekah Bullard, Surendra Raj Sharma, Pradipta Kumar Das, Sarah E. Morgan, Shahid Karim

Faculty Publications

Tick feeding requires the secretion of a huge number of pharmacologically dynamic proteins and other molecules which are vital for the formation of the cement cone, the establishment of the blood pool and to counter against the host immune response. Glycine-rich proteins (GRP) are found in many organisms and can function in a variety of cellular processes and structures. The functional characterization of the GRPs in the tick salivary glands has not been elucidated. GRPs have been found to play a role in the formation of the cement cone; however, new evidence suggests repurposing of GRPs in the tick physiology. …

Making Sure Your Voice Is Heard Lgbtqi Documentation For End Of Life, Kenneth J. Mangano Bhas, Mcm

Patient Care Services / Nursing

No abstract provided.

Ada News - 06/17/2019, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

The Effect Of Disclosure On Adherence To Antiretroviral Therapy Among Adults Living With Hiv In Ethiopia: A Systematic Review And Meta-Analysis., Getenet Dessie, Fasil Wagnew, Henok Mulugeta, Dessalegn Amare, Dube Jara, Cheru Tesema Leshargie, Ayenew Negesse, Swati Rayasam, Sahai Burrowes

BACKGROUND: Several factors have been identified as being associated with increased adherence to antiretroviral therapy, including sero-status disclosure; however, studies examining the effect of disclosure on ART adherence in Ethiopia have had inconsistent findings. This systematic review and meta-analysis therefore aims to estimate the pooled effect of disclosure on adherence to ART among adults living with HIV in Ethiopia.

METHODS: We performed a systematic search for articles reporting on peer-reviewed, quantitative, English-language observational studies of reporting the association between self sero-status disclosure and good ART adherence in adults living with HIV/AIDS in Ethiopia during published from 2010 to 2015. We …

Responding To Biological Attacks, Barry Kellman

DePaul Journal of Health Care Law

No abstract provided.

Public Health Preparedness & Response: An Exercise In Administrative Law, John D. Blum, Jordan Paradise

DePaul Journal of Health Care Law

No abstract provided.

Porcine Interferon Complex And Co-Evolution With Increasing Viral Pressure After Domestication, Jordan Jennings, Yongming Sang

Agricultural and Environmental Sciences Faculty Research

Consisting of nearly 60 functional genes, porcine interferon (IFN)-complex represents an evolutionary surge of IFN evolution in domestic ungulate species. To compare with humans and mice, each of these species contains about 20 IFN functional genes, which are better characterized using the conventional IFN-α/β subtypes as examples. Porcine IFN-complex thus represents an optimal model for studying IFN evolution that resulted from increasing viral pressure during domestication and industrialization. We hypothesize and justify that porcine IFN-complex may extend its functionality in antiviral and immunomodulatory activity due to its superior molecular diversity. Furthermore, these unconventional IFNs could even confer some functional and …

Scale Optimization Of Milkguard Biosensor For Detecting E. Coli In Human Breast Milk, Jerard Roniel Del Rosario Madamba

Bioengineering Master's Theses

Milkguard is an alginate-based biosensor developed to detect E. coli in human breast milk via the metabolism of X-gal (5-Bromo-4-Chloro-3-Indolyl β-D-Galactopyranoside) by β-galactosidase. In order to deconvolute metabolic reproducibility from scaling laws, the commercial enzyme β-galactosidase was used to mimic the biological function of the bacterial lac operon. Downscaling was explored as an optimization of the biosensor design based on numerical solutions to Fickian-based diffusion models. The characterization of large capsules (d ≅ 3 mm) and atomized microcapsules (d ≅ 300 ± 60 μm) yielded size-specific Michaelis-Menten constants. Small capsules (K_m = 3.6 x 10^-4 M; Vmax ’’ …

A Rapid Viability And Drug‑Susceptibility Assay Utilizing Mycobacteriophage As An Indicator Of Drug Susceptibilities Of Anti‑Tb Drugs Against Mycobacterium Smegmatis Mc2 155, Gillian Catherine Crowley, Jim O'Mahony, Aidan Coffey, Riona G. Sayers, Paul D. Cotter

Department of Biological Sciences Publications

Background: A rapid in-house TM4 mycobacteriophage-based assay, to identify multidrug resistance against various anti-tuberculosis drugs, using the fast-growing Mycobacterium smegmatis mc² 155 in a microtiter plate format was evaluated, based on phage viability assays. Methods: A variety of parameters were optimized before the study including the minimum incubation time for the drugs, phage and M. smegmatis mc² 155 to be in contact. An increase in phage numbers over 2 h was indicative that M. smegmatis mc² 155 is resistant to the drugs under investigation, however when phage numbers remained static, M. smegmatis mc² 155 found to …

Antimicrobial Susceptibility Against Metronidazole And Carbapenem In Clinical Anaerobic Isolates From Pakistan, Kauser Jabeen, Yusra Shafquat, Joveria Farooqi, Kiran Mehmood, Seema Irfan, Rumina Hasan, Afia Zafar

Department of Pathology and Laboratory Medicine

Background: Globally metronidazole and carbapenem resistance in anaerobic organisms is increasing necessitating continuous surveillance to guide selection of empirical treatment. In this study we have determined metronidazole resistance in anaerobes using MIC Evaluator strips (M.I.C.E strips). Carbapenem resistance was evaluated only in metronidazole resistant isolates.
Material and methods: The study was conducted at the Aga Khan University (AKU) Hospital laboratory, Karachi, Pakistan (2014–2017). Metronidazole and imipenem resistance was evaluated using M.I.C.E strips and minimum inhibitory concentrations (MICs) were interpreted using Clinical Laboratory Standards Institute (CLSI) criteria. Clinical details including demographics, prolonged hospital stay, malignancy, transplant, dialysis, diabetes, site of infection …

Collaborative Molecular Epidemiology Study Of Metabolic Dysregulation, Dna Methylation, And Breast Cancer Risk Among Nigerian Women: Mend Study Objectives And Design, Tomi Akinyemiju, Omolola Salako, Adetola Daramola, Olusegun Alatise, Adewale Adeniyi, Gabriel Ogun, Omobolaji Ayandipo, Thomas Olajide, Olalekan Olasehinde, Olukayode Arowolo, Adewale Adisa, Oludolapo Afuwape, Aralola Olusanya, Aderemi Adegoke, Akinlolu Ojo, Trygve Tollefsbol, Donna K. Arnett

Epidemiology and Environmental Health Faculty Publications

PURPOSE To elucidate the role of metabolic dysregulation and associated DNA methylation changes on breast cancer risk and aggressive subtypes among Nigerian women. We describe the design and methods of a collaborative molecular epidemiology study of breast cancer in Nigerian hospitals.

METHODS The Mechanisms for Novel and Established Risk Factors for Breast Cancer in Women of Nigerian Descent (MEND) study was designed as a matched case-control study of 350 patients, age 18 to 75 years, with newly diagnosed, treatment-naïve breast cancer and 350 age-matched healthy controls from surrounding geographic areas. Patients with breast cancer seen for initial diagnosis at four …

Phage Therapy Against Biofilm Of Multidrug-Resistant Klebsiella Pneumoniae Isolated From Zakho Hospital Samples, Yousif Abdullah Albany, Mohammad Ismail Al-Berfkani, Mahde Saleh Assafi

Polytechnic Journal

Klebsiella pneumoniae causes infection in human, especially in immunocompromised patients. About 80% of nosocomial infection caused by K. pneumoniaeis due to multidrug-resistant strain. The emergence of antibiotic-resistant bacterial strains necessitates the exploration of alternative antibacterial therapies, which led to studying the ability of viruses that infect the bacteria (known as bacteriophage) to treat infection with K. pneumoniae. Bacterial biofilm which are crucial in the pathogenesis of much clinically important infection and are difficult to eradicate because they exist resistant to many antimicrobial treatment. Biofilm formation by K. pneumoniae is responsible for the catheter associated infection such as urinary tract infection …

Cardiovascular Factors Moderate The Association Of Infection Burden With Cognitive Function In Young To Middle-Aged U.S. Adults, Bruce L. Brown, Shawn D. Gale, Lance D. Erickson, Dawson W. Hedges, Andrew N. Berrett, Evan L. Thacker

Faculty Publications

Background: Infectious diseases might affect cognitive aging and dementia risk, possibly via neuroinflammation. Similarly, risk factors for cardiovascular and cerebrovascular diseases are associated with cognitive function and dementia. We hypothesized that cardiovascular risk factors moderate the association of exposure to infectious diseases with cognitive function.

Methods: We studied 5662 participants aged 20 to 59 years from the third National Health and Nutrition Examination Survey (1988–1994) in the United States. We used linear regression to investigate whether the Framingham general cardiovascular risk index moderated the association of infection burden based on exposure to eight different infectious diseases with cognitive functioning as …

Antibiotic Resistant Bacteria Isolated From Michigan Birds - A High School Learning Experience, Cody Benfant

Honors Theses

Bacteria, extremely small prokaryotic cells, are everywhere throughout the world. One striking thing about bacteria is their size: comparing a 2-micrometer bacterial cell to a 6-foot-tall human is similar in scale to comparing a 6-foot-tall human to the distance between Chicago, IL and Denver, CO! Despite their small size, bacteria are found in almost every ecosystem and environment imaginable. From deep sea hydrothermal vents to the clouds miles in the sky, there are trillions of bacteria flourishing in all of Earth’s ecosystems, performing many important functions in global nutrient cycles. While the majority of bacteria are beneficial to humans, …