Digital Commons Network^™

Anatomy And Physiology I & Ii (Uga, Scaling Up Oer), Deloris Hesse, Lindsey Beebe, Ann Massey, Daniel Mcnabney, Rob Nichols

Biological Sciences Grants Collections

This Grants Collection for Anatomy and Physiology I & II was created under a Spring 2018 Pilot for G2C and Scaling Up OER Textbook Transformation Grant.

Affordable Learning Georgia Grants Collections are intended to provide faculty with the frameworks to quickly implement or revise the same materials as a Textbook Transformation Grants team, along with the aims and lessons learned from project teams during the implementation process.

Each collection contains the following materials:

• Linked Syllabus or Syllabi
• Initial Proposal
• Final Report

Effects Of Short-Term Human-Horse Interactions On Human Heart Rate Variability: A Multiple Single Case Study, Saan Ecker, Amy Lykins

People and Animals: The International Journal of Research and Practice

Influences from human-horse interactions form the basis of the emerging field of equine-assisted psychotherapy (EAP). However, the psychophysiological effects of horses on humans in the EAP context have been underinvestigated. This multiple single case design study examined the effects of short-term human-horse interactions on human heart rate variability (HRV). Nine adults with limited prior experience with horses participated in time-limited in vivo exposures to five different free-roaming horses in a yard. Results were mixed with HRV improving from a preexposure baseline in 40% and deteriorating in 23% of the 43 ten-minute horse-human interactions. In the remaining horse-human interactions, HRV was …

Age At Menarche, Measures Of The Midlife Gut Microbiome, And Cardiovascular Risk Factors, Yan Wang

Theses and Dissertations

Introduction Early menarche has been associated with greater risks of cardiovascular disease (CVD) and CVD-related mortality but the mechanisms remain unclear. We hypothesized that early menarche and CVD may share as a common cause, changes in the natural history of the gut microbiome. Methods We obtained data on 2,400 adult female twins from the TwinsUK registry. Participants reported their age at menarche retrospectively and underwent anthropometric and clinical laboratory measures in 1992-2014. They provided fecal samples in 2007-2012. Microbial DNA sequences represent the V4 region of the 16S rRNA gene. OTU-picking was done using open-reference strategy in QIIME and the …

Cold Exposure Induces Dynamic, Heterogeneous Alterations In Human Brown Adipose Tissue Lipid Content, Crystal L. Coolbaugh, Bruce M. Damon, Emily C. Bush, E Brian Welch, Theodore F. Towse

Peer Reviewed Articles

Brown adipose tissue undergoes a dynamic, heterogeneous response to cold exposure that can include the simultaneous synthesis, uptake, and oxidation of fatty acids. The purpose of this work was to quantify these changes in brown adipose tissue lipid content (fat-signal fraction (FSF)) using fat-water magnetic resonance imaging during individualized cooling to 3 °C above a participant’s shiver threshold. Eight healthy men completed familiarization, perception-based cooling, and MRI-cooling visits. FSF maps of the supraclavicular region were acquired in thermoneutrality and during cooling (59.5 ± 6.5 min). Brown adipose tissue regions of interest were defined, and voxels were grouped into FSF decades …

Medical School Watercooler Newsletter - September 15, 2019, Lindsey Lyle

Watercooler Newsletter

This is the September 15, 2019 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

Pediatric intensivist joins USA College of Medicine faculty

Medical Spanish Interest Group and SRFC care for Latino immigrant population

Register Now: Obstetrics and Gynecology Conference

Med School Café video online: "What Is Urogynecology?"

The Effect Of Barefoot Running On Emg Activity In The Gastrocnemius And Tibialis Anterior In Active College-Aged Females, Ryan Beierle, Phoebe Burton, Hayden Smith, Michael Smith, Stephen J. Ives

International Journal of Exercise Science

International Journal of Exercise Science 12(1): 1110-1120, 2019. Running is one of the most popular forms of exercise, thus overuse injuries such as plantar fasciitis, shin splints, and tibial stress fractures are also common. Barefoot/forefoot running has shown promise to reduce overuse injuries by decreasing the impact upon contact with the ground. The arch of the foot utilizes a ‘spring’ system that simultaneously reduces impact and propels the stride forward. Increased muscle activity in a particular location is indicative of greater impact forces, suggesting a larger risk for overuse injuries. The current study investigated the role of the barefoot condition …

Gower Embodies Uab's Collaborative Spirit Through Cross-Campus Partnerships, Haley Herfurth

Browse All News

No abstract provided.

More Anatomically Realistic And Quantitative Models Of Pulmonary Surfactant Action And Alveolar Stability, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Working Papers

To explore basic mechanisms of action of pulmonary surfactant in preventing alveolar collapse, a first-principles analysis is done analyzing forces on the shared walls separating adjacent alveolar gas bubbles. The analysis holds for concave alveolar models with either rounded, dome-like surfaces or flat, box-like surfaces. The analysis also holds for neighboring alveoli of varying size and shape. Surfactant action is characterized by two parameters describing reduction in surface tension vs. log concentration. The resulting equations describe the net pressure tending to shift the shared position of a wall, as a function of the perturbation from a balanced initial state. In …

Unraveling The Functional Role Of The Orphan Solute Carrier, Slc22a24 In The Transport Of Steroid Conjugates Through Metabolomic And Genome-Wide Association Studies, Sook Wah Yee, Adrian Stecula, Huan-Chieh Chien, Ling Zou, Elena V Feofanova, Marjolein Van Borselen, Kit Wun Kathy Cheung, Noha A Yousri, Karsten Suhre, Jason M Kinchen, Eric Boerwinkle, Roshanak Irannejad, Bing Yu, Kathleen M Giacomini

Faculty, Staff and Student Publications

Variation in steroid hormone levels has wide implications for health and disease. The genes encoding the proteins involved in steroid disposition represent key determinants of interindividual variation in steroid levels and ultimately, their effects. Beginning with metabolomic data from genome-wide association studies (GWAS), we observed that genetic variants in the orphan transporter, SLC22A24 were significantly associated with levels of androsterone glucuronide and etiocholanolone glucuronide (sentinel SNPs p-value

The “Rights” Of Precision Drug Development For Alzheimer’S Disease, Jeffrey Cummings, Howard H. Feldman, Philip Scheltens

School of Medicine Faculty Research

There is a high rate of failure in Alzheimer’s disease (AD) drug development with 99% of trials showing no drug-placebo difference. This low rate of success delays new treatments for patients and discourages investment in AD drug development. Studies across drug development programs in multiple disorders have identified important strategies for decreasing the risk and increasing the likelihood of success in drug development programs. These experiences provide guidance for the optimization of AD drug development. The “rights” of AD drug development include the right target, right drug, right biomarker, right participant, and right trial. The right target identifies the appropriate …

A Comparison Of Lung Function Values Among A Scuba Diver Population And In Comparison To A Non-Diver Population, Gabriel C. Hutson, Jeremy D. Rentsch, Erin M. Eaton

Journal of the South Carolina Academy of Science

The purpose of this study was to investigate possible correlations between lung function values (PEF, IRV, ERV, and FVC) among a diver population, as well as in comparison to a non-diver population. Independent variables for both populations were biological sex, age, and weekly physical activity. Independent variables for the diver population were dive tenure, number of logged dives, certification level, and gas mixture used. A spirometry test was conducted to collect lung function values of both populations. Data from this study suggest a statistically significant relationship between diver and non-diver sex and FVC, diver age and ERV, diver sex and …

Initial Development Of A Prototype Sensor Testbed For Fetal Monitoring, Christian Beauvais

Theses and Dissertations

The objective of this research is to design and manufacture a device that exhibits some of the bio-physiological signals relevant to fetal health monitoring. Currently, limited options exist for testing the performance of monitoring devices such as the tocodynamometer (TOCO) and electrocardiograph (ECG) that measure the bio-physiological signals of a woman and her fetus. Sensor designers need ways of generating and acquiring signals that do not carry the ethical burden of human testing. The development of such a device, as considered in this work, may involve using muscle wire or an inflatable tube as prospective foundations for simulating uterine contraction. …

Using Microsoft Hololens To Improve Memory Recall In Anatomy And Physiology: A Pilot Study To Examine The Efficacy Of Using Augmented Reality In Education, Chen Chen, Lei Zhang, Tony Luczak, Eboni Smith, Reuben F. Burch

Journal of Educational Technology Development and Exchange (JETDE)

This paper explores the use of augmented reality (AR) to improve memory recall and learning experiences in human anatomy and physiology. In particular, the opportunity to assess new computer technologies to improve learning environments may allow for an improvement in self-efficacy and a reduction in test anxiety. Twenty-two undergraduates participated in one of two study groups, the Microsoft HoloLens group (HLNS) or the traditional projector-based Microsoft Power Point group (PPT). Each group completed a five-minute, three-subject anatomy identification and brain physiology memory test. After a three-minute time delay, participants completed a fill-in-the-blank anatomy identification test and brain physiology question test, …

Our Envirome, Spring/Summer 2019, Issue 40

Sustain Magazine

No abstract provided.

Recent Trends, Current Research In Cyberpsychology: A Literature Review, Amarjit Kumar Singh, Pawan Kumar Singh

Library Philosophy and Practice (e-journal)

Cyberpsychology refers to the study of the mind and behavior in the context of interactions with technology. It is an emerging branch, which has focused on the psychological aspects connected to the increasing presence and usages of technology in modern lives. This paper traces recent advancement and trends of Cyberpsychology is an emerging domain of knowledge and goes on the give a literature review of the same. An analysis of the recent research and literature covering 300 most relevant research papers from the period of 2012 to 15, August 2019 was conducted to determine and shape the research pattern based …

Emergent Behavior Development And Control In Multi-Agent Systems, David W. King

Theses and Dissertations

Emergence in natural systems is the development of complex behaviors that result from the aggregation of simple agent-to-agent and agent-to-environment interactions. Emergence research intersects with many disciplines such as physics, biology, and ecology and provides a theoretical framework for investigating how order appears to spontaneously arise in complex adaptive systems. In biological systems, emergent behaviors allow simple agents to collectively accomplish multiple tasks in highly dynamic environments; ensuring system survival. These systems all display similar properties: self-organized hierarchies, robustness, adaptability, and decentralized task execution. However, current algorithmic approaches merely present theoretical models without showing how these models actually create hierarchical, …

Measures Of Fluid Loss During Surfing: A Preliminary Analysis In Recreational Surfers, Rudi A. Meir, Zachary James Crowley-Mchattan Dr, Lyndon O. Brooks, Blake Duncan, Christian Gorrie, Jeremy Sheppard

International Journal of Aquatic Research and Education

Surfing is a popular sport, but little is known about the extent to which recreational surfers experience fluid loss from this activity. The principal objective of this research was to estimate fluid loss during a surfing session through changes in pre- to post-session urine color (Ucol), urine osmolality (Uosm), and body mass (BM). Data were collected from 11 recreational surfers across 14 surf sessions conducted under various environmental (mean water temperature = 22.1 SD ± 2.3; range = 20-26^oC; air temperature range = 13.1-31.5^oC; relative humidity range = 37.5-88.1%) and surfing conditions (e.g. winter/summer, wave type, …

Dissociable Learning Processes, Associative Theory, And Testimonial Reviews: A Comment On Smith And Church (2018, Andy J. Wills, Charlotte E.R. Edmunds, Pelley M Le, Fraser Milton, Ben R. Newell, Dominic M. Dwyer, David R. Shanks

School of Psychology

No abstract provided.

Evaluation Of Cobb Mv × Cobb 500 Broiler Response To Various Nutrient Regimens To Maximize Performance And Economics, Rosana Hirai

Theses and Dissertations

To maximize the economics of a new commercial broiler cross, research on its nutritional specifications is necessary. Study 1 investigated the effects of feeding four amino acid densities (AAD) on performance and yield of Cobb MV × Cobb 500 broilers at d 33 and 36. Data demonstrated a stepwise decrease in feed conversion ratio (FCR) as AAD level increased. Improvements in performance, processing, and economic return were observed when feeding higher AAD levels. Study 2 estimated the digestible lysine (dLys) requirements of Cobb MV × Cobb 500 broilers from d 0-14 and evaluated the impact of varying starter dLys levels …

Understanding Biomechanical Constraints For Modelling Expressive Performance: A Guitar Case Study, Leandro L. Costalonga, Marcelo S. Pimenta, Eduardo R. Miranda

School of Art, Design and Architecture

No abstract provided.

Expression And Function Of Nesfatin-1 Are Altered By Stage Of The Estrous Cycle, Alicia T. Pate, Abigayle L. Schnell, Teresa A. Ennis, Willis K. Samson, Gina L.C. Yosten

Biological Sciences Faculty Research & Creative Works

Nesfatin-1 is a peptide derived from the nucleo-bindin 2 (Nucb2) precursor protein that has been shown to exert potent effects on appetite and cardiovascular function in male animals. Sex hormones modulate the expression of Nucb2 in several species, including goldfish, mouse, and rat, and human studies have revealed differential expression based on male or female sex. We therefore hypothesized that the ability of nesfatin-1 to increase mean arterial pressure (MAP) would be influenced by stage of the estrous cycle. Indeed, we found that in cycling female Sprague-Dawley rats, nesfa-tin-1 induced an increase in MAP on diestrus, when both estrogen and …

A Flavor Perception Game Designed To Introduce Basic Chemical Sensation Of Taste Modalities To Undergraduate Nursing And Exercise Sciences Students, Angela L. Mahaffey

Nursing: School of Nursing Faculty Publications and Other Works

The Flavor Perception Game was designed with the goals of developing an interactive and hands-on activity, providing a platform to review chemical senses of the five tastes, promoting student investment in the course material, and providing a basis for discussion on chemical senses of the five tastes. Knowledge of taste sensation is useful for nursing and exercise sciences students, as human physiology is integral to both baccalaureate curricula. The game is inexpensive, easy to incorporate into a 50-minute lecture period, and free of chocolate allergens. Student participants (N=34) tasted three candies and completed a voluntary anonymous poll regarding their detection …

Organically Modified Inorganic Nanoparticles For Halochromic Ionophores And Nucleic Acids, William Johnston

Doctoral Dissertations

In this dissertation, four nanoparticle reaction schemes were developed as substrates for halochromic dyes or nucleic acids. The reaction schemes include the use of two substrates: silica nanoparticles and halloysite nanotubes. The protocols can incorporate silica (SiO2) nanoparticles and halloysite aluminosilicate (AlO2SiO2) nanotubes due to the presence of silane groups on the surface of either substrate. The reaction schemes are presented along with detailed protocols which were written to facilitate both reproducibility and to serve as an aid to further study and for easy modification of the protocol to suit a researcher's needs. The data is discussed in the materials …

Characterization Of B-Lymphoblast Lines Derived From A Severely Autistic Child, Both Parents, And Donor Controls, Delia Juliana

All Theses

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition affecting approximately 1% of the population. It occurs roughly four times more in males than females, and includes individuals with classic autism, as well as those with "incomplete" forms. Behavioral characteristics include, but are not limited to: restricted, stereotyped, and repetitive actions, as well as impairments in communication and social interaction. At the Greenwood Genetics Center, Greenwood, SC, ASD patients and control donors provided peripheral blood as a source of lymphocytes, and a skin-scrape sample as a source of fibroblasts for genetic analysis. A severely autistic patient, coded as B26, his two …

Gender In Apocalyptic California: The Ecological Frontier, Marykate Eileen Messimer

Graduate Theses and Dissertations

Climate change is the consequence of ideologies that promote human reproduction and resource consumption by sacrificing human justice, nonhuman species, and the land. Both biology and queer ecologies resist this notion of human separation and supremacy by showing that no body is a singular, impermeable entity, that all beings are biologically and inexorably connected. My dissertation demonstrates that fiction writers use this knowledge to locate a utopian vision that can counteract the dystopian impotence of living within climate change. This argument is founded on novels written by women and set in California, a state that uniquely inhabits a utopian and …

Characterization Of The Swine Gut Microbiome Dynamics, Culturomics And Probiotics, Xiaofan Wang

Graduate Theses and Dissertations

The gastrointestinal tract is a critical place where the immune system concentrates many of its protective functions. It exerts both physical and biochemical defenses against invading foodborne pathogens and other hazards. In pigs, the gut microbiota community assembled postnatal plays a very important role in the development of multiple physiologic aspects, such as development of the gastrointestinal tract, nutrient exchange, immune defense against foreign pathogens and growth performance. Microbiome-host communication changes with age. Despite recent advances in understanding the swine gut microbiome at different growth stages, a comprehensive longitudinal study of the lifelong dynamics of the swine gut microbiome is …

Sex And Death On The Western Emigrant Trail: The Biology Of Three American Tragedies, Debra E. L. Martin

Anthropology Faculty Research

This book offers a different look at how to think about the starvation and death that hounded emigrants attempting to get to California and Oregon in the early years of nineteenth-century US expansion. Specifically, the Donner party and two lesser-known Mormon handcart groups are scrutinized for what the patterns of age at death by sex can reveal. In the subtitle The Biology of Three American Tragedies, “biology” here means solely demographic data on sex and age at death. These are really the only biological variables examined, so the title Sex and Death on the Western Emigrant Trail is more accurate …

Heat Waves And Heat-Related Mortality In East Tennessee, Taiwo Adesoba

Electronic Theses and Dissertations

Heat waves represent a public health challenge that requires multiple responses and warnings to protect vulnerable populations. Although studies have reported an increasing trend of heat wave occurrence in many areas of the world, no clear trend exists in East Tennessee. Using data from Parameter-elevated Relationships on Independent Slope Models (PRISM), CDC WONDER and the United States Census Bureau, the relationship between mortality rates and year was estimated during heat wave events between 1999 and 2010. Five heat wave definitions were tested. Overall, 2007 and 2010 stand out as the years with the highest number of heat wave days in …

Modeling Extreme Heat Events Using Global Reanalysis Data: An Assessment Of Current Climate Data And The Need For Improved Weather Station Data In Tennessee, John Reasons

Electronic Theses and Dissertations

Wet Bulb Globe Temperature (WBGT) is used to assess categorical heat stress risk factors for individuals working in outdoor environments and to provide guidelines for work/rest ratios and water intake. The variables required to compute WBGT are used by meteorologists for many purposes and are available through the Copernicus Program which was implemented by European Centre for Medium-Range Weather Forecasts (ECMWF) to provide users access to ECMWF Re-Analysis (ERA) historical database. WBGT values for Tennessee during National Weather Service (NWS) issued excessive heat warnings were calculated to determine the need for additional advisories based on WBGT guidelines. Monthly average WBGT …

Effects Of Alternative Carbohydrate Sources And Soybean-Derived Isoflavones On The Microbiome And Immune System Of Nursery Piglets And Intestinal Porcine Epithelial Cell Line J-2, Sydney Kinstler

Department of Animal Science: Dissertations, Theses, and Student Research

Four experiments were conducted to characterize the microbiome of the piglet and observe effects of diet on growth performance and immunity. In Exp. 1, 96 nursery piglets were fed varying carbohydrate sources and in Exp. 2, 64 piglets were fed a soy protein concentrate or soybean meal as-is or supplemented with an isoflavone concentrate. Body and feeder weights were measured for growth performance estimation. Luminal contents and scrapings were isolated for microbial composition analysis. Fecal and blood samples were extracted in Exp. 2 for microbiome and immunity analysis. Diets did not affect growth performance (P > 0.10); however, Exp. 1 …