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2019

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The Effects Of Supplementation Of Rumen-Protected Choline On Some Blood And Milk Metabolites In The Transition Period Of Dairy Cattle, Ni̇yazi̇ Alan, Mustafa Salman Jan 2019

The Effects Of Supplementation Of Rumen-Protected Choline On Some Blood And Milk Metabolites In The Transition Period Of Dairy Cattle, Ni̇yazi̇ Alan, Mustafa Salman

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to investigate nonesterified fatty acid (NEFA), beta-hydroxy butyric acid (BHBA), and milk urea nitrogen (MUN) profiles for dairy cows fed with rumen-protected choline (RPC) during the transition period. A total of 30 dairy cows were allocated to one control and two experimental groups (10 animals per group) and were fed from 3 weeks before calving to 21 days in milk. The control was fed only the basal diet. Treatment groups 1 and 2 were fed a basal diet containing 60 and 120 g/head/day RPC, respectively. The differences between groups were insignificant for MUN levels …

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Cointegration Analysis Of Wild And Farmed Sea Bream And Sea Bass Prices In Turkey, Mehmet Saltuk Arikan, Ahmet Cumhur Akin, Mustafa Bahadir Çevri̇mli̇, Mustafa Agah Teki̇ndal Jan 2019

Cointegration Analysis Of Wild And Farmed Sea Bream And Sea Bass Prices In Turkey, Mehmet Saltuk Arikan, Ahmet Cumhur Akin, Mustafa Bahadir Çevri̇mli̇, Mustafa Agah Teki̇ndal

Turkish Journal of Veterinary & Animal Sciences

Market integration is an indicator of the extent to which different products are interrelated, and the presence of market integration between products suggests that they are substitutes. The objective of this study was to determine the market interaction between wild and farmed products of two fish species, namely sea bream and sea bass. For this purpose, the relationship between the producer price time series of cultured sea bream, wild sea bream, cultured sea bass, and wild sea bass in the period of 2009-2017 was tested using the cointegration analysis technique. It was found that the wild sea bream and sea …

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Serodiagnostic Potential Of Brucella Outer Membrane And Periplasmic Proteins, Aitbay Bulashev, Orken Akibekov, Zhanbolat Suranshiyev, Bakytkali Ingirbay, Saule Eskendirova Jan 2019

Serodiagnostic Potential Of Brucella Outer Membrane And Periplasmic Proteins, Aitbay Bulashev, Orken Akibekov, Zhanbolat Suranshiyev, Bakytkali Ingirbay, Saule Eskendirova

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to evaluate the serological diagnostic potential of the Brucella recombinant outer membrane (rOMP25, rOMP31) and periplasmic proteins (rBP26, rSOD) in a comparative way using an indirect enzyme-linked immunosorbent assay (i-ELISA). Rabbit and/or mouse antibodies to Brucella whole cell and/or soluble protein preparations recognized all recombinant proteins used, which confirms the expression of target antigens in E. coli in active form. The recombinant proteins showed different antigenicity to antibodies of cattle kept on a brucellosis-affected (endemic) farm and/or a new focus of infection. Thus, the presence of anti-Brucella antibodies was confirmed by i-ELISA/rSOD in 79% …

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Morphometric Analysis Of The Skulls Of Domestic Cattle (Bos Taurus L.) And Water Buffalo (Bubalus Bubalis L.) In Turkey, Ermi̇ş Özkan, Abu Bakar Siddiq, Ki̇fayet Oya Kahveci̇oğlu, Muhsi̇n Öztürk, Vedat Onar Jan 2019

Morphometric Analysis Of The Skulls Of Domestic Cattle (Bos Taurus L.) And Water Buffalo (Bubalus Bubalis L.) In Turkey, Ermi̇ş Özkan, Abu Bakar Siddiq, Ki̇fayet Oya Kahveci̇oğlu, Muhsi̇n Öztürk, Vedat Onar

Turkish Journal of Veterinary & Animal Sciences

A total of 20 domestic cattle (Bos taurus L.) and 15 water buffalo (Bubalis bubalis L.) skulls were analyzed in this study. All of the specimens belonged to female individuals. Using a total of 27 craniometric measurements from each of the skulls, 9 indices were calculated. Although there were statistically significant differences between the linear measurements of the skulls of both species, while calculating the indices with their ratios, the values of the measurements of the facial area were determinative in the craniology. Among these indices, the facial index 1 value was statistically significant (P < 0.01) in the comparison of these two species. On the other hand, while considering the orbit and foramen magnum measurements, in contrast with the transversal measurement, the height was more determinant for their index and form.

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Snake Envenomation In Two Cattle: Clinical/Laboratory Aspects And Treatment Using Equine-Derived Antivenin Of Viperidae, Nuri̇ Altuğ, Cafer Tayer İşler Jan 2019

Snake Envenomation In Two Cattle: Clinical/Laboratory Aspects And Treatment Using Equine-Derived Antivenin Of Viperidae, Nuri̇ Altuğ, Cafer Tayer İşler

Turkish Journal of Veterinary & Animal Sciences

In this case report, specific antivenin treatment for Viperidae snake envenomation in two cattle was defined for the first time. The diagnosis of snake envenomation was made according to the history and clinical findings. Clinical examination revealed systemic (tachycardia, dyspnea, cyanosis, hypersalivation, ruminal hypotony) and local (swelling of the leg and head) findings depending on the location of snake bites. Laboratory analysis determined granulocytic leukocytosis, monocytosis, decreased iron binding capacity, and increased CK and LDH enzyme activities. In the specific treatment of cases, equine-derived polyvalent antivenin containing antitoxic immunoglobulins against Viperidae species was administered. Additionally, 5% dextrose, antibiotics, dexamethasone, antihistamines, …

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Molecular Detection And Phylogenetic Analysis Of The Honeybee (Apis Mellifera) Sacbrood Virus In Turkey, Gülnur Kalayci, Abdurrahman Anil Çağirgan, Kemal Pekmez, Buket Özkan, Murat Kaplan Jan 2019

Molecular Detection And Phylogenetic Analysis Of The Honeybee (Apis Mellifera) Sacbrood Virus In Turkey, Gülnur Kalayci, Abdurrahman Anil Çağirgan, Kemal Pekmez, Buket Özkan, Murat Kaplan

Turkish Journal of Veterinary & Animal Sciences

Sacbrood virus (SBV) is widely distributed in honeybees. It is an infectious and contagious disease, which affects both the larvae and adult stages of honeybees (Apis mellifera). This study reports the detection of sacbrood virus in Turkey in 2017. Phylogenetic analysis based on partial sequences encoding the polyprotein gene was carried out in SBV-infected bees from four different apiaries. Phylogenetic analysis revealed noteworthy results. Although European-South American, Asian, and Korean genotypes have a maximum of 5.3% variance with each other, the variation rates between them and the Turkish genotype were 10.4%, 11.4%, and 12.5%, respectively. Sequences of Turkish isolates did …

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Molecular Detection Of Anaplasma Spp. In Blood And Milk Of Dairy Cattle In The Philippines, Angelito Pangan Dela Cruz, Remil Linggatong Galay, Kristina Andrea Claveria Sandalo, Flor Marie Immanuelle Rafallo Pilapil-Amante, Tetsuya Tanaka Jan 2019

Molecular Detection Of Anaplasma Spp. In Blood And Milk Of Dairy Cattle In The Philippines, Angelito Pangan Dela Cruz, Remil Linggatong Galay, Kristina Andrea Claveria Sandalo, Flor Marie Immanuelle Rafallo Pilapil-Amante, Tetsuya Tanaka

Turkish Journal of Veterinary & Animal Sciences

Anaplasmosis has become a major concern in the cattle industry throughout the world due to its great economic impact. The causative agents, Anaplasmaspecies, are primarily transmitted by ticks, occurring intracellularly within blood cells, with some species being zoonotic. In this study, the presence of Anaplasma spp. was investigated in the blood and milk of dairy cattle in the Philippines. Blood and milk samples were collected from 98 dairy cattle from selected farms in five provinces in the southern part of Luzon Island in the Philippines. After DNA extraction, a conventional PCR for the control gene actin was performed, followed by …

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The Effect Of Anesthetic (2-Phenoxyethanol) Application On Some Biochemical And Hematological Parameters In Russian Sturgeon (Acipenser Gueldenstaedtii) And Siberian Sturgeon (Acipenser Baerii) During Transport, Selçuk Duman Jan 2019

The Effect Of Anesthetic (2-Phenoxyethanol) Application On Some Biochemical And Hematological Parameters In Russian Sturgeon (Acipenser Gueldenstaedtii) And Siberian Sturgeon (Acipenser Baerii) During Transport, Selçuk Duman

Turkish Journal of Veterinary & Animal Sciences

Experiments were carried out to determine the effect of 2-phenoxyethanol to reduce stress response during the transportation of Russian and Siberian sturgeons. In transportation experiment 1 (TE$_{1}$), Siberian sturgeons (687.2 ± 17.41 g) were stocked in tanks and transported for 90 min (stocking density = 65 ± 0.71 kg/$m^{3}$). Before transport, 0.5 mg/L 2-phenoxyethanol was applied to the first group (TE$_{1-A}$, n = 285) but not to the second group (TE$_{1-B}$, n = 287). In transportation experiment 2 (TE2), Russian sturgeons (1873 ± 159 g) were divided into two groups and stocked in tanks as they have a density of …

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A Prospective Clinical Investigation Of The Effects Of Anti-Tnf Alpha Therapy On Exercise Capacity In Patients With Ankylosing Spondylitis, Erhan Çapkin, Seyhan Bi̇lge Keski̇n, Murat Karkucak, Ahmet Ayar Jan 2019

A Prospective Clinical Investigation Of The Effects Of Anti-Tnf Alpha Therapy On Exercise Capacity In Patients With Ankylosing Spondylitis, Erhan Çapkin, Seyhan Bi̇lge Keski̇n, Murat Karkucak, Ahmet Ayar

Turkish Journal of Medical Sciences

The purpose of this study was to investigate possible effects of anti-TNF alpha therapy on cardiorespiratory fitness and physical functional capacity of patients with ankylosing spondylitis (AS). Materials and methods: Twenty-eight AS patients meeting the modified New York criteria with active disease state and an equivalent number of healthy individuals as the control were prospectively enrolled. Physical working capacity and aerobic exercise capacity of the participants were determined by using cardiopulmonary exercise tests, performed before and 4 months after initiation of anti-TNF alpha therapy. Results: The mean age of the patients was 37 ± 9.1 years, and mean duration of …

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Abnormal Retinal Microvasculature Found In Active Rheumatoid Arthritis:A Different Perspective Of Microvascular Health, Hakan Babaoğlu, Ata Baytaroğlu, Murat Torğutalp, Abdulsamet Erden, Si̇bel Kadayifçilar, Umut Kalyoncu Jan 2019

Abnormal Retinal Microvasculature Found In Active Rheumatoid Arthritis:A Different Perspective Of Microvascular Health, Hakan Babaoğlu, Ata Baytaroğlu, Murat Torğutalp, Abdulsamet Erden, Si̇bel Kadayifçilar, Umut Kalyoncu

Turkish Journal of Medical Sciences

We aimed to assess the association between retinal vascular caliber (RVC) scores and disease activity in rheumatoid arthritis (RA) patients.Materials and methods: Forty-seven RA patients, 32 systemic lupus erythematosus (SLE) patients, and 45 healthy people were enrolled. RA and SLE patients were subdivided into groups according to C-reactive protein (CRP) levels. RA patients were also grouped according to Disease Activity Score-28 (DAS-28). Fundus photography was performed for all patients. RVC was summarized as the central retinal artery and vein equivalents (CRAE and CRVE).Results: Mean CRVE for RA patients was 213.3 ± 17.8 µm compared with 209.2 ± 14.1 µm for …

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High Rates Of Malnutrition And Epilepsy: Two Common Comorbidities In Children With Cerebral Palsy, Kürşad Aydin, Ayşe Kartal, Esma Keleş Alp Jan 2019

High Rates Of Malnutrition And Epilepsy: Two Common Comorbidities In Children With Cerebral Palsy, Kürşad Aydin, Ayşe Kartal, Esma Keleş Alp

Turkish Journal of Medical Sciences

The aim of this study was to evaluate the nutritional status of children with cerebral palsy and determine the particular characteristics of the disorder. Materials and methods: The nutritional status of the children was assessed by the Gomez classification using weight-for-age. The Gross Motor Function Classification System was used to determine the gross and fine motor functions.Results: The study was conducted with 197 children (58.4% males) between the ages of 1 and 18 years old. Asphyxia (44.1%) was the primary etiological factor, and spastic quadriplegia (41.6%) was the most common type of cerebral palsy. Malnutrition was the most frequent comorbidity …

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Comparison Of Early And Long Term Outcomes Of Open Lichtenstein Repair And Totally Extraperitoneal Herniorrhaphy For Primary Inguinal Hernias, Bariş Sevi̇nç, Nurullah Damburaci, Murat Güner, Ömer Karahan Jan 2019

Comparison Of Early And Long Term Outcomes Of Open Lichtenstein Repair And Totally Extraperitoneal Herniorrhaphy For Primary Inguinal Hernias, Bariş Sevi̇nç, Nurullah Damburaci, Murat Güner, Ömer Karahan

Turkish Journal of Medical Sciences

Inguinal hernia repair is one of the most common surgical procedures worldwide. There is still controversy over which method has the best postoperative results. The aim of this study was to compare early and late postoperative results of laparoscopic totally extraperitoneal herniorrhaphy (TEP) and open Lichtenstein herniorrhaphy (OLR). Materials and methods: The study was conducted in a randomized prospective manner and it was concluded with 302 patients (147 cases in TEP group and 155 cases in OLR group). All procedures were performed by two experienced surgeons in both open and laparoscopic inguinal hernia repair.Results: The groups were similar in terms …

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Differentiation Between Intestinal Behçet's Disease And Crohn's Disease Based On Endoscopy, Jing Fen Ye, Jian Long Guan Jan 2019

Differentiation Between Intestinal Behçet's Disease And Crohn's Disease Based On Endoscopy, Jing Fen Ye, Jian Long Guan

Turkish Journal of Medical Sciences

Differentiating intestinal Behçet's disease (BD) from Crohn's disease (CD) is highly challenging, as they often mimic each other in terms of clinical manifestations. Endoscopy is an important modality for distinguishing bowel lesions. The study was designed to identify clinical manifestations that are easily confused and to evaluate the efficacy of endoscopy for distinguishing intestinal BD from CD by several overlapping signs.Materials and methods: The data from 111 patients with intestinal BD and 81 patients with CD were retrospectively analyzed. Logistic regression was applied to establish a prediction model based on endoscopic findings for the differential diagnosis. The diagnostic efficacy of …

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The Effects Of Uterine Size With Or Without Abdominal Obesity On Spinal Block Level And Vasopressor Requirement In Elective Cesarean Section: A Prospective Observational Study, İlkben Günüşen, Asuman Sargin, Ali̇ Akdemi̇r, Ahmet Mete Ergenoğlu Jan 2019

The Effects Of Uterine Size With Or Without Abdominal Obesity On Spinal Block Level And Vasopressor Requirement In Elective Cesarean Section: A Prospective Observational Study, İlkben Günüşen, Asuman Sargin, Ali̇ Akdemi̇r, Ahmet Mete Ergenoğlu

Turkish Journal of Medical Sciences

Hypotension is a serious complication caused by spinal anesthesia that places both the mother and fetus at increased risk. We aimed to investigate the effects of uterine size with or without abdominal obesity on sensory block level of pregnant women receiving spinal anesthesia. Materials and methods: This study included 125 term parturients who underwent cesarean section. Motor and sensory block characteristics, the distance between the symphysis pubis and the fundus (SPF), the distance between the symphysis pubis and the xiphoid (SPX), newborn and placental weights, adverse effects, and doses of ephedrine were recorded. Results: Sensory block level and ephedrine dose …

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Current Perspectives For The Treatment Of Chronic Myeloid Leukemia, Eli̇fcan Aladağ Karakulak, İbrahi̇m Celaletti̇n Haznedaroğlu Jan 2019

Current Perspectives For The Treatment Of Chronic Myeloid Leukemia, Eli̇fcan Aladağ Karakulak, İbrahi̇m Celaletti̇n Haznedaroğlu

Turkish Journal of Medical Sciences

With an annual incidence of 1-2 in a million, Ph*(+) chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell disease that makes myeloid neoplastic cells breed out of control. This BCR-ABL(+) myeloproliferative disease makes up about 15%-20% of all leukemia cases in adults. CML is seen more in males than females, with a rate of three to two. However, it does not show differences in prevalence in terms of age. CML consists of three clinical phases. The first one is the chronic phase, defined by rising white blood cell levels and also by myeloid proliferation and bone marrow maturation. …

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The Role Of Hepcidin, Gdf15, And Mitoferrin-1 In Iron Metabolism Of Polycythemia Vera And Essential Thrombocytosis Patients, Canan Albayrak Yaşar, Pinar Tarkun, Eli̇f Bi̇rtaş Ateşoğlu, Fatma Ceyla Eraldemi̇r, Özgür Doğa Özsoy, Esra Terzi̇ Demi̇rsoy, Özgür Mehtap, Ayfer Gedük, Abdullah Haci̇hani̇fi̇oğlu Jan 2019

The Role Of Hepcidin, Gdf15, And Mitoferrin-1 In Iron Metabolism Of Polycythemia Vera And Essential Thrombocytosis Patients, Canan Albayrak Yaşar, Pinar Tarkun, Eli̇f Bi̇rtaş Ateşoğlu, Fatma Ceyla Eraldemi̇r, Özgür Doğa Özsoy, Esra Terzi̇ Demi̇rsoy, Özgür Mehtap, Ayfer Gedük, Abdullah Haci̇hani̇fi̇oğlu

Turkish Journal of Medical Sciences

GDF15, hepcidin and mitoferrin-1 (mfrn-1) are proteins involved in systemic iron regulation. There are no studies in the literature demonstrating the serum mfrn-1 levels in polycythemia vera (PV) and essential thrombocythemia (ET) patients. The aim of this study was to investigate GDF15, hepcidin and mfrn-1 levels in PV and ET patients.Materials and methods: Ten PV, 17 ET patients, and 27 healthy controls (HCs) were enrolled. GDF15, hepcidin and mfrn-1 values were measured with enzyme-linked immunosorbent assay (ELISA).Results: GDF15 levels were higher in the myeloproliferative neoplasm (MPN) group (P = 0.002). Hepcidin levels were not different between MPN patients and HCs. …

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The Investigation Of Strongyloides Stercoralis Seroprevalence In Immunosupressed Patients In Turkey, Fi̇li̇z Kaya, Ahmet Çağkan İnkaya, Ali̇ İhsan Ertenli̇, Osman Abbasoğlu, Sercan Aksoy, Yakut Akyön Yilmaz, Si̇bel Ergüven Jan 2019

The Investigation Of Strongyloides Stercoralis Seroprevalence In Immunosupressed Patients In Turkey, Fi̇li̇z Kaya, Ahmet Çağkan İnkaya, Ali̇ İhsan Ertenli̇, Osman Abbasoğlu, Sercan Aksoy, Yakut Akyön Yilmaz, Si̇bel Ergüven

Turkish Journal of Medical Sciences

In immunosuppressed patients, strongyloidiasis can be lifethreatening because of hyperinfection or dissemination. Therefore, diagnosis of S. stercoralis is important in immunosuppressed patients with chronic strongyloidiasis. In this study, our objective was to investigate the presence of S. stercoralis antibodies by an ELISA method in immunosuppressed patients. Materials and methods: A total of 100 immunosuppressed patients' sera were included in the study. Forty-two of the patients were receiving immunosuppressive therapies for cancer or being treated for hematopoietic malignancies, 38 of the patients were receiving immunosuppressive drugs for rheumatic diseases, 14 were receiving immunosuppressive therapies for liver transplantation. Two of the patients …

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A Neglected Causative Agent In Diabetic Foot Infection: A Retrospective Evaluation Of 13 Patients With Fungal Etiology, Anil Murat Ozturk, Meltem Taşbakan, Di̇lek Yeşi̇m Meti̇n, Can Yener, Serhat Uysal, Ilgin Yildirim Şi̇mşi̇r, İlgen Ertam, Hüsnü Pullukçu, Bi̇lgi̇n Arda, Şevki̇ Çeti̇nkalp Jan 2019

A Neglected Causative Agent In Diabetic Foot Infection: A Retrospective Evaluation Of 13 Patients With Fungal Etiology, Anil Murat Ozturk, Meltem Taşbakan, Di̇lek Yeşi̇m Meti̇n, Can Yener, Serhat Uysal, Ilgin Yildirim Şi̇mşi̇r, İlgen Ertam, Hüsnü Pullukçu, Bi̇lgi̇n Arda, Şevki̇ Çeti̇nkalp

Turkish Journal of Medical Sciences

Clinicians often neglect fungal infections and do not routinely investigate deep tissue from the wound for fungal culture and sensitivity due to insufficient information in the literature. In this study, we aimed to evaluate fungal etiology of invasive fungal diabetic foot which is rarely reported in the literature.Materials and methods: The patients who were unresponsive to antibiotic therapy and those with positive fungal in bone or deep tissue culture were enrolled in the study. Detailed hospital records were retrieved for demographics and clinical features. Results: A total of 13 patients who were diagnosed with invasive fungal diabetic foot (ten females, …

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Fatigue And Sleep In Children And Adolescents With Juvenile Idiopathic Arthritis:A Cross-Sectional Study, Ela Tarakci, Sai̇me Ni̇lay Arman, Kenan Barut, Sezgi̇n Şahi̇n, Amra Adrovi̇ç, Özgür Kasapçopur Jan 2019

Fatigue And Sleep In Children And Adolescents With Juvenile Idiopathic Arthritis:A Cross-Sectional Study, Ela Tarakci, Sai̇me Ni̇lay Arman, Kenan Barut, Sezgi̇n Şahi̇n, Amra Adrovi̇ç, Özgür Kasapçopur

Turkish Journal of Medical Sciences

The aims of this study were to primarily investigate fatigue and sleep and to secondarily examine possible relationships between disease activity, pain, and functional ability in children and adolescents with juvenile idiopathic arthritis (JIA). Materials and methods: Ninety-six patients were enrolled in the study. Disease activity, functional ability, fatigue symptoms, fatigue severity, and sleep quality were assessed with the Juvenile Arthritis Disease Activity Score (JADAS), Childhood Health Assessment Questionnaire (CHAQ), Pediatric Quality of Life Inventory-Multidimensional Fatigue Scale (PedsQL-F), visual analog scale (VAS), and Pittsburgh Sleep Quality Index (PSQI), respectively. Results: Fatigue severity was moderate to high in 75% of patients …

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Comparison Of Reference Systems In The Assessment Of Age-Related Serum Immunoglobulin Levels In Pediatric Patients, İlknur Külhaş Çeli̇k, Ersoy Ci̇velek, Ayşe Meti̇n, Tayfur Gi̇ni̇ş, Müge Toyran, Emi̇ne Di̇bek Misirlioğlu, Can Naci̇ Kocabaş Jan 2019

Comparison Of Reference Systems In The Assessment Of Age-Related Serum Immunoglobulin Levels In Pediatric Patients, İlknur Külhaş Çeli̇k, Ersoy Ci̇velek, Ayşe Meti̇n, Tayfur Gi̇ni̇ş, Müge Toyran, Emi̇ne Di̇bek Misirlioğlu, Can Naci̇ Kocabaş

Turkish Journal of Medical Sciences

Ig level assessment is frequently used in the diagnosis and follow-up of immunodeficiency, as well as in studies investigating the prevalence of low serum Ig level in specific diseases.Material and methods: Patients who underwent Ig testing in the inpatient and outpatient clinics of our hospital in the years 2010-2016 were included. The Ig levels of the patients were assessed separately according to two reference systems commonly used in Turkey and another reference system used in the USA.Results: A total of 20,138 patients (57.6% male) were included in the study. The median age of the patients was 55.7 months (interquartile range: …

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A Comparison Of The Effects Of Mirror Therapy And Phantom Exercises On Phantom Limb Pain, Bahar Külünkoğlu, Fati̇h Erbahçeci̇, Afra Alkan Jan 2019

A Comparison Of The Effects Of Mirror Therapy And Phantom Exercises On Phantom Limb Pain, Bahar Külünkoğlu, Fati̇h Erbahçeci̇, Afra Alkan

Turkish Journal of Medical Sciences

Although mirror therapy (MT) and phantom exercises (PE) have been shown to reduce pain, the efficacy of these methods in terms of pain, quality of life (QoL), and psychological status (PS) has not been investigated and compared to date. The aim of this study was to determine whether there is any difference between MT and PE in the treatment of phantom limb pain (PLP).Materials and methods: Forty unilateral transtibial amputees (aged 18-45 years) participated in this study. The subjects were randomly divided into `MT group' and `PE group'. QoL was assessed using Short-Form 36 (SF-36), psychological status using the Beck …

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8-Armed Octopus: Evaluation Of Clinicopathologic Prognostic Factors Of Urothelial Carcinoma Of The Upper Urinary System, Sümeyye Ekmekci̇, Ülkü Küçük, Yelda Dere, İzzeti̇ye Ebru Çakir, Hati̇ce Ceren Sayar, Batuhan Ergani̇, Özgür Çakmak, Ozan Bozkurt, Kutsal Yörükoğlu Jan 2019

8-Armed Octopus: Evaluation Of Clinicopathologic Prognostic Factors Of Urothelial Carcinoma Of The Upper Urinary System, Sümeyye Ekmekci̇, Ülkü Küçük, Yelda Dere, İzzeti̇ye Ebru Çakir, Hati̇ce Ceren Sayar, Batuhan Ergani̇, Özgür Çakmak, Ozan Bozkurt, Kutsal Yörükoğlu

Turkish Journal of Medical Sciences

This study was designed to determine the characteristic features of upper urinary system urothelial carcinomas (UUSUCs) and to evaluate the clinicopathological parameters associated with prognosis.Materials and methods: A total of 74 cases of UUSUC were included, from three different centers. Demographic data and histopathological features such as tumor localization, concomitant tumor in the urinary system, distant metastasis with overall survival and disease-free survival obtained from the hospital records were evaluated retrospectively. Histopathologic prognostic features such as grade, perineural invasion, lymphovascular invasion, tumor necrosis, and surgical margin status were also evaluated.Results: Seventy cases (94.6%) underwent open nephroureterectomy whereas 4 cases (5.4%) …

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Reliability And Validity Of The Turkish Version Of The Physical Activity Questionnaire For Older Children (Paq-C), Leyla Erdi̇m, Ayşe Ergün, Sema Kuğuoğlu Jan 2019

Reliability And Validity Of The Turkish Version Of The Physical Activity Questionnaire For Older Children (Paq-C), Leyla Erdi̇m, Ayşe Ergün, Sema Kuğuoğlu

Turkish Journal of Medical Sciences

The Physical Activity Questionnaire for Older Children (PAQ-C) is one of the most frequently used questionnaires for evaluating moderate to vigorous levels of physical activity in children. However, a Turkish version of the questionnaire was not available. This study aimed to create a Turkish version of the PAQ-C and examine its psychometric characteristics and factor structure.Materials and methods: The study was conducted with 784 primary school students (ages 9-14 years). The PAQ-C was examined for content and construct validity and analyzed in terms of reliability. Content validity was evaluated with the content validity index (CVI), construct validity, exploratory factor analysis …

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Which Nostril Should Be Used For Nasotracheal Intubation With Airtraq Nt®: The Right Or Left? A Randomized Clinical Trial, Zehra İpek Arslan Aydin, Neşe Türkyilmaz Jan 2019

Which Nostril Should Be Used For Nasotracheal Intubation With Airtraq Nt®: The Right Or Left? A Randomized Clinical Trial, Zehra İpek Arslan Aydin, Neşe Türkyilmaz

Turkish Journal of Medical Sciences

Nasotracheal Airtraq is specifically designed to improve the glottis view and ease the nasotracheal intubation process in normal and difficult cases. Materials and methods: After Ethics committee approval, we decided to enroll 40 patients with an ASA physical status of I or II, between 18 and 70 years of age undergoing elective maxillofascial, oral, and double chin surgery to determine which nostril is more suitable for nasotracheal intubation with nasotracheal Airtraq. Patients were randomized into the right and left nostril groups. Results: Demographic and airway characteristics were similar among the groups. Nasotracheal intubation through the right nostril was shorter than …

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Ischemic Modified Albumin As A New Biomarker In Predicting Oxidative Stress In Alopecia Areata, Hati̇ce Ataş, Müzeyyen Gönül, Yasi̇n Öztürk, Mustafa Kavutçu Jan 2019

Ischemic Modified Albumin As A New Biomarker In Predicting Oxidative Stress In Alopecia Areata, Hati̇ce Ataş, Müzeyyen Gönül, Yasi̇n Öztürk, Mustafa Kavutçu

Turkish Journal of Medical Sciences

Results show that oxidative stress is a pathophysiologic factor for alopecia areata (AA); however, the markers used can be confounding. Thus, we aimed to investigate the role of oxidative stress in the pathogenesis of AA through an evaluation of ischemia-modified albumin (IMA); other markers of the oxidant/antioxidant system, such as SOD, CAT, GSH-ST, and MDA; and contributing clinical risk factors. Materials and methods: The usefulness of IMA as a new marker for oxidative stress was compared with that of other markers and evaluated in patients with AA.Results: The mean serum level of IMA was of higher statistical significance in AA …

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Determination Of Medication Adherence And Related Factors Among People Living With Hiv/Aids In A Turkish University Hospital, Erdal Ceylan, Ayşegül Koç, Ahmet Çağkan İnkaya, Serhat Ünal Jan 2019

Determination Of Medication Adherence And Related Factors Among People Living With Hiv/Aids In A Turkish University Hospital, Erdal Ceylan, Ayşegül Koç, Ahmet Çağkan İnkaya, Serhat Ünal

Turkish Journal of Medical Sciences

Widespread use of antiretroviral treatment (ART) has led to decrease in the incidence of HIV/AIDS-related mortality. Besides the availability of ART, medication adherence is essential for treatment success. There is a scarcity of data reported from Turkey regarding ART adherence among people living with HIV/AIDS (PLWHA). Therefore, this study was undertaken to determine medication adherence and related factors among PLWHA in Turkey.Materials and methods: The sample consisted of 158 PLWHA, who were being followed up at Infectious Diseases Outpatient Clinic of Hacettepe University Hospital. Data were collected using an individual questionnaire and the Turkish version of the Morisky Medication Adherence …

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The Role Of Ifih1 Gene Rs1990760 And Rs2111485 Single-Nucleotide Polymorphisms In Generalized Vitiligo Predisposition, Duru Onan, Ahu Yorulmaz, Fati̇h Süheyl Ezgü, Kadi̇r Mutlu Hayran, Seray Külcü Çakmak, Refi̇ka Ferda Artüz, Başak Yalçin Jan 2019

The Role Of Ifih1 Gene Rs1990760 And Rs2111485 Single-Nucleotide Polymorphisms In Generalized Vitiligo Predisposition, Duru Onan, Ahu Yorulmaz, Fati̇h Süheyl Ezgü, Kadi̇r Mutlu Hayran, Seray Külcü Çakmak, Refi̇ka Ferda Artüz, Başak Yalçin

Turkish Journal of Medical Sciences

Interferon-induced helicase (IFIH1) is a gene locus that has been recently defined as a candidate for susceptibility to generalized vitiligo (GV). The objectives of this study were to assess the association of IFIH1 gene, rs2111485, and rs1990760 single-nucleotide polymorphisms (SNP) with susceptibility to GV and the autoimmune diseases accompanying GV.Materials and methods: We prospectively studied GV patients and frequency-matched healthy controls by age and sex. The genotypes of the participants were determined for rs1990760 and rs2111485 SNPs of IFIH1. Dominant, recessive, and additive models were evaluated for each SNP adjusted for age and sex. Results: The patients and their controls …

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Association Of Common Il-10 Promoter Gene Variants With The Susceptibility To Head And Neck Cancer In Tunisia, Lamia Makni, Cherif Ben Hamda, Abrar Al Ansari, Oussema Souaiai, Ezzedine Gazouani, Amel Mezlini, Wassim Y. Almawi, Besma Yacoubi-Loueslati Jan 2019

Association Of Common Il-10 Promoter Gene Variants With The Susceptibility To Head And Neck Cancer In Tunisia, Lamia Makni, Cherif Ben Hamda, Abrar Al Ansari, Oussema Souaiai, Ezzedine Gazouani, Amel Mezlini, Wassim Y. Almawi, Besma Yacoubi-Loueslati

Turkish Journal of Medical Sciences

Background/aim: We investigated the association of three IL-10 promoter single-nucleotide polymorphisms and altered IL-10 plasma levels with the risk of head and neck cancer (HNC). Materials and methods: Study subjects comprised 194 HNC patients [137 nasopharyngeal cancer (NPC) and 57 laryngeal cancer (LC)], and 263 healthy controls. Genotyping of rs1800896 (-1082A>G), rs1800871 (-819C>T), and rs1800872 (-592A>C) IL-10 variants was performed by real-time PCR; IL-10 levels were measured by enzyme amplified immuno sensitivity assay (EAISA). Results: Carriage of rs1800896 A/A genotype was more frequent in the HNC and NPC cases, but was less frequent in the controls than …

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Possible Prediction Of Patterns Of Cervical Lymph Node Spread Based On Primary Tumor Location In Papillary Thyroid Carcinomas, Mehmet Eser Sancaktar, Güleser Saylam, Bülent Öcal, Ahmet Uluat, Ömer Bayir, Erman Çakal, Mehmet Hakan Korkmaz Jan 2019

Possible Prediction Of Patterns Of Cervical Lymph Node Spread Based On Primary Tumor Location In Papillary Thyroid Carcinomas, Mehmet Eser Sancaktar, Güleser Saylam, Bülent Öcal, Ahmet Uluat, Ömer Bayir, Erman Çakal, Mehmet Hakan Korkmaz

Turkish Journal of Medical Sciences

Backround/aim: Papillary thyroid carcinomas (PTC) frequently metastasize to regional lymph nodes. Our purpose was to investigate the predictive role of tumor location for lymph node metastasis pattern in PTCs.Materials and methods: Medical records of 110 PTC patients were reviewed retrospectively. Tumor location was determined as upper, middle, and lower pole according to ultrasonography (USG) findings. The effects of age, sex, tumor size, and location on lymph node metastasis were investigated. Results: The series comprised 87% females (n = 96) and 13% males (n = 14). Forty-three patients had central neck metastasis (CNM) and 14 had lateral neck metastasis (LNM). Upper …

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Polypharmacy And Drug-Related Problems Among People Living With Hiv/Aids: A Single-Center Experience, Emre Kara, Ahmet Çağkan İnkaya, Duygu Aydin Hakli, Salih Kutay Demirkan, Serhat Ünal Jan 2019

Polypharmacy And Drug-Related Problems Among People Living With Hiv/Aids: A Single-Center Experience, Emre Kara, Ahmet Çağkan İnkaya, Duygu Aydin Hakli, Salih Kutay Demirkan, Serhat Ünal

Turkish Journal of Medical Sciences

The HIV-infected population is aging, and the concomitant comorbidities increase the likelihood of polypharmacy. There is a scarcity of data for determining drug-related problems in people living with HIV/AIDS (PLWHA). Materials and methods: This cross-sectional study was carried out between 1 September 2015 and 1 July 2016. All patients underwent a face-to-face interview with a clinical pharmacist. PCNE Classification V 7.0 was used classify incident drug-related problems (DRPs). Results: The mean age of the patients was 40.4 ± 13.06 years. The rate of polypharmacy was 66.1% in patients with comorbidities and 12.3% in those without comorbidities (P < 0.001). DRPs were more prominent in older patients (46 vs. 37 years, P < 0.001), those with longer durations of antiretroviral therapy (ART) (45 vs. 27 months, P = 0.014), and those with lower education levels (P = 0.013). Receiving >3 ART drugs …

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