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2019

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Heavy Metal Accumulation As A Threat To The Endangered Egyptian Vulture(Neophron Percnopterus L.) In Turkey, Eli̇f Yamaç, Menekşe Özden, Sunay Balaban, Semra Malkoç Jan 2019

Heavy Metal Accumulation As A Threat To The Endangered Egyptian Vulture(Neophron Percnopterus L.) In Turkey, Eli̇f Yamaç, Menekşe Özden, Sunay Balaban, Semra Malkoç

Turkish Journal of Zoology

Due to anthropogenic activity, most vulture species are threatened. Neophron percnopterus, the Egyptian vulture, is a vulture species with a declining population. One of the most important factors threatening the species is exposure to chemicals. The second largest population of this bird species is found in Turkey. Accumulation of heavy metals for this species has not been investigated. The aim of this study was to detect and measure As, Cd, Cr, Cu, Hg, Ni, Pb, and Zn values in the feathers of Neophron percnopterus. Calamis and vane, which are different part of the feathers, were analyzed separately with ICP-OES. According …

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Neuroprotective Role Of Delta Opioid Receptors In Hypoxic Preconditioning, Şevi̇n Güney, Si̇bel Di̇ncer, Güleser Göktaş, Gülnur Take Kaplanoğlu Jan 2019

Neuroprotective Role Of Delta Opioid Receptors In Hypoxic Preconditioning, Şevi̇n Güney, Si̇bel Di̇ncer, Güleser Göktaş, Gülnur Take Kaplanoğlu

Turkish Journal of Medical Sciences

Background/aim: The purpose of the present study was to explore the neuroprotective role of delta opioid receptors (DOR) in the rat cortex in hypoxic preconditioning. Materials and methods: Rats were randomly divided into 8 groups: control (C), sham (S), hypoxic preconditioning (PC), severe hypoxia (SH), PC + SH, PC + SH + Saline (PS), PC + SH + DPDPE (DPDPE, selective DOR agonist), PC + SH + NT (NT, Naltrindole, selective DOR antagonist). Drugs were administered intracerebroventrically. Twenty four h after the end of 3 consecutive days of PC (10% O2, 2 h/day), the rats were subjected to severe hypoxia …

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Seasonal, Sex Variations In Vitamin D Levels And Their Association With Pulmonary Function In Children With Asthma, Şebnem Özdoğan Jan 2019

Seasonal, Sex Variations In Vitamin D Levels And Their Association With Pulmonary Function In Children With Asthma, Şebnem Özdoğan

Turkish Journal of Medical Sciences

Background/aim: We aimed to examine the seasonal and sex variations in vitamin D levels in children with asthma and their associations with lung function. Materials and methods: We conducted a cohort study involving children aged 7?17 years old with asthma. Vitamin D levels were obtained and pulmonary function tests (PFTs) were performed in winter months (December, January, and February) and at the end of summer (August, September, and October). Seasonal and sex variations in vitamin D levels and lung function were examined. Results: A total of 56 children (26 males, mean age: 11.93 ± 1.8) were enrolled. The mean vitamin …

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A Novel Marker Relationship Between Carotid Intima-Media Thickness And Disease Activity Score-28 In Patients With Rheumatoid Arthritis: Human Endothelial Cell-Specific Molecule-1, Göksel Tuzcu, Ali̇ Uğur Uslu, Ayça Tuzcu, Rabi̇a Aydoğan Baykara, Ahmet Omma, Adem Küçük Jan 2019

A Novel Marker Relationship Between Carotid Intima-Media Thickness And Disease Activity Score-28 In Patients With Rheumatoid Arthritis: Human Endothelial Cell-Specific Molecule-1, Göksel Tuzcu, Ali̇ Uğur Uslu, Ayça Tuzcu, Rabi̇a Aydoğan Baykara, Ahmet Omma, Adem Küçük

Turkish Journal of Medical Sciences

Background/aim: Human endothelial cell-specific molecule-1 (endocan) is a marker of vascular endothelial dysfunction that may be used in the evaluation of inflammatory-associated atherosclerotic lesions. Endocan may be a marker for the evaluation of atherosclerosis and disease activity in rheumatoid arthritis (RA) patients.Materials and methods: We included 39 RA patients assessed according to the American College of Rheumatology/European League Against Rheumatology 2010 diagnostic criteria and recruited 30 age- and sex-matching healthy subjects for the control group.Results: Endocan values were 14.11 ± 3.27 for the RA patients and 12.10 ± 2.92 for the controls. The endocan values of the patients were significantly …

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The Role Of Right Ventricular Volumes And Inferior Vena Cava Diameters In The Evaluation Of Volume Status Before Colonoscopy, Şule Arican, Ramazan Dertli̇, Çağdaş Dağli, Gülçi̇n Hacibeyoğlu, Mustafa Koyuncu, Ahmet Topal, Sema Tuncer Uzun, Mehmet Asil Jan 2019

The Role Of Right Ventricular Volumes And Inferior Vena Cava Diameters In The Evaluation Of Volume Status Before Colonoscopy, Şule Arican, Ramazan Dertli̇, Çağdaş Dağli, Gülçi̇n Hacibeyoğlu, Mustafa Koyuncu, Ahmet Topal, Sema Tuncer Uzun, Mehmet Asil

Turkish Journal of Medical Sciences

Background/aim: Ultrasonographic measurements of inferior vena cava (IVC) diameters and right ventricle (RV) volumes are important tools for the evaluation of intravascular volume. The current study investigates the association of IVC diameters and RV volumes before colonoscopy in prediction of postanesthesia hypotension.Materials and methods: Seventy patients scheduled for colonoscopy were included in the study. Preoperatively, expirium (dIVC max) and inspirium (dIVC min) IVC diameters were measured using M-mode ultrasonography and the collapsibility index (IVC-CI) was calculated. Ventricular volumes and areas were also measured using transthoracic echocardiography. Postanesthesia hypotension was defined as mean arterial blood pressure of 30% in the mean …

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Initial Regional Evaluation Of The Cystic Fibrosis Newborn Screening Program: Data From The Mediterranean Coast Of Turkey, Abdurrahman Erdem Başaran, Ayşen Başaran, Di̇lara Fatma Kocacik, Özgül Alper, Deni̇z Acican, Ayşen Bi̇ngöl Jan 2019

Initial Regional Evaluation Of The Cystic Fibrosis Newborn Screening Program: Data From The Mediterranean Coast Of Turkey, Abdurrahman Erdem Başaran, Ayşen Başaran, Di̇lara Fatma Kocacik, Özgül Alper, Deni̇z Acican, Ayşen Bi̇ngöl

Turkish Journal of Medical Sciences

Background/ aim: Since January 2015, the Cystic Fibrosis Newborn Screening (CFNS) program has been implemented in Turkey. We aimed to evaluate the demographic, clinical, and laboratory data of cases referred from the CFNS program and to determine the most suitable cut-off value for immunoreactive trypsinogen (IRT)-1 and immunoreactive trypsinogen (IRT-2) that are used in the CFNS program in Turkey. Materials and methods: A total of 156 Turkish Caucasian subjects were determined as positive cases during 3 years, from January 2015 to January 2018, and were referred to the pediatric pulmonology clinics of Akdeniz University Hospital, Antalya, Turkey, for the national …

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The Validity And Reliability Of The Turkish Version Of The Physical Activity Scale For Individuals With Physical Disabilities (Pasipd), Kardem Ulaş, Semra Topuz, Gönül Horasan Jan 2019

The Validity And Reliability Of The Turkish Version Of The Physical Activity Scale For Individuals With Physical Disabilities (Pasipd), Kardem Ulaş, Semra Topuz, Gönül Horasan

Turkish Journal of Medical Sciences

Background/aim: The aim of this study is to assess the validity and reliability of Turkish translation of thePhysical Activity Scale for Individuals with Physical Disabilities (PASIPD) in a disabled Turkish population.Materials and methods: Following the translation protocol of the PASIPD, the Turkish version of the PASIPD, Short Form-36, and International Physical Activity Questionnaire were administered to 198 developmentally and physically disabled individuals.Results: The Turkish version of the PASIPD was found to be reliable. The domains of the Turkish version of the PASIPD were also found to be valid. Four factors were obtained from the questionnaire. The ICC was 1.0 since …

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The Effect Of Parathyroidectomy On Bone Mineral Density In Primary Hyperparathyroidism, Mustafa Çalişkan, Selvi̇han Beysel, Muhammed Kizilgül, Mustafa Özbek, Erman Çakal Jan 2019

The Effect Of Parathyroidectomy On Bone Mineral Density In Primary Hyperparathyroidism, Mustafa Çalişkan, Selvi̇han Beysel, Muhammed Kizilgül, Mustafa Özbek, Erman Çakal

Turkish Journal of Medical Sciences

Background/aim: This study aimed to investigate the change in bone mineral density (BMD) before and 1 year after parathyroidectomy in patients with primary hyperparathyroidism (PHPT). Materials and methods: The clinical and biochemical parameters and DEXA screening of patients with symptomatic PHPT (n = 28) and asymptomatic PHPT (n = 63) were investigated before and 1 year after parathyroidectomy. Results: Patients with symptomatic PHPT had a higher prevalence of nephrolithiasis (18.2% vs. 4.6%, P = 0.032) when compared to the prevalence in patients with asymptomatic PHPT. The prevalence of osteoporosis in the lumbar spine (63.0% vs. 37.5%, P = 0.026) and …

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Clinical Results Of Intradiscal Hydrogel Administration (Gelstix) In Lumbar Degenerative Disc Disease, Ayşegül Ceylan, İbrahi̇m Aşik, Güngör Enver Özgenci̇l, Burak Erken Jan 2019

Clinical Results Of Intradiscal Hydrogel Administration (Gelstix) In Lumbar Degenerative Disc Disease, Ayşegül Ceylan, İbrahi̇m Aşik, Güngör Enver Özgenci̇l, Burak Erken

Turkish Journal of Medical Sciences

Background/aim: Degenerative disc disease (DDD) is one of the main causes of lower back pain. In this study, we evaluate the efficacy of percutaneous intradiscal GelStix administration in patients with discogenic pain due to lumbar DDD who were unresponsive to conservative methods.Materials and methods: A total of 29 patients were included in the study, which took place between 2013 and 2017. Sedation was performed in the prone position in the operating room, and a C-arm was located so as to provide a lateral view of the surgical field. A 22-G, 3.5-inch needle was inserted into the center of the disc …

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Pipeline Flex Embolization Device (Ped Flex) For The Treatment Of Intracranial Aneurysms: Periprocedural Outcomes And First-Year Angiographic Results, Şükrü Oğuz, Ömer Naci̇ Tabakci, Ender Uysal, Eser Bulut, Hasan Di̇nç Jan 2019

Pipeline Flex Embolization Device (Ped Flex) For The Treatment Of Intracranial Aneurysms: Periprocedural Outcomes And First-Year Angiographic Results, Şükrü Oğuz, Ömer Naci̇ Tabakci, Ender Uysal, Eser Bulut, Hasan Di̇nç

Turkish Journal of Medical Sciences

Background/aim: The Pipeline Flex Embolization Device (PED Flex) is a new updated version of the PED classic that incorporates a new delivery system to allow facilitation of stent deployment, resheathing, and removal of the capture coil. This study evaluated the PED Flex in terms of the technical aspects of the procedure and first-year follow-up results. Materials and methods: This retrospective study involved prospectively collected data from May 2015 to August 2017. The primary endpoint was technical aspects of the procedure, and the secondary endpoint was first-year follow-up results. Results: Forty-nine patients with 59 target intracranial aneurysms were enrolled. Patients' mean …

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The Effect Of Pregabalin On Tourniquet-Induced Ischemia-Reperfusion Injury:A Prospective Randomized Study, Ömer Karaca, Hüseyi̇n Ulaş Pinar, Ahmet Fevzi̇ Özgür, Sevsen Kulaksizoğlu, Rafi̇ Doğan Jan 2019

The Effect Of Pregabalin On Tourniquet-Induced Ischemia-Reperfusion Injury:A Prospective Randomized Study, Ömer Karaca, Hüseyi̇n Ulaş Pinar, Ahmet Fevzi̇ Özgür, Sevsen Kulaksizoğlu, Rafi̇ Doğan

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to investigate the efficacy of pregabalin on ischemia-reperfusion injuries.Materials and methods: Fifty-four patients were randomly assigned into 2 groups. A 150-mg tablet of pregabalin was given the night before and then 1 h before the operation for patients in Group P (pregabalin group, n = 27). A placebo was given to patients in Group C (control group, n = 27) at the same times. After combined spinal-epidural anesthesia was performed, venous blood samples were taken before tourniquet inflation (t1), just before tourniquet deflation (t2), and 20 min after tourniquet deflation (t3) for the …

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Abdominal Girth Has A Strong Correlation With Actual And Ultrasound Estimated Epidural Depth, Mehmet Cantürk, Nazan Kocaoğlu, Meltem Hakki Jan 2019

Abdominal Girth Has A Strong Correlation With Actual And Ultrasound Estimated Epidural Depth, Mehmet Cantürk, Nazan Kocaoğlu, Meltem Hakki

Turkish Journal of Medical Sciences

Background/aim: This study aimed to assess the correlations of actual epidural depth (ND) and ultrasound estimated epidural depth in the paramedian sagittal oblique plane (ED/PSO) and transverse median plane (ED/TM) with the abdominal girth (AG), body mass index (BMI), and weight of patients. Materials and methods: One hundred and thirty patients of either sex scheduled for unilateral inguinal hernia repair were enrolled. ED/PSO and ED/TM were assessed with a 2-5 MHz curved array probe at the L3-4 intervertebral space. The epidural needle was marked with a sterile marker upon locating the epidural space. The ND was assessed by measuring the …

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Assessment Of The Visual Pathways In Patients With Neurofibromatosis-1 By 3s-Space Technique With 3-Tesla Mri, Özge Saraç, Oktay Algin, Mehmet Beyazal, Fatma Banu Anlar, Ali̇ Varan, Adi̇le Tülay Kansu Jan 2019

Assessment Of The Visual Pathways In Patients With Neurofibromatosis-1 By 3s-Space Technique With 3-Tesla Mri, Özge Saraç, Oktay Algin, Mehmet Beyazal, Fatma Banu Anlar, Ali̇ Varan, Adi̇le Tülay Kansu

Turkish Journal of Medical Sciences

Background/aim: We aimed to evaluate the size/tortuosity of the optic nerve (ON) and the dilatation of the ON sheath (ONS) in neurofibromatosis type 1 (NF-1) patients with 3T-MRI, and to assess the usefulness of 3D-SPACE in imaging the optic pathway, ON, and ONS in NF-1 patients. Materials and methods: Twenty consecutive NF-1 patients without optic pathway glioma (OPG) (Group 1), 16 consecutive NF-1 patients with OPG (Group 2), and 19 controls were included in this study. The thickness and tortuosity of the ON and the diameter of the ONS were measured on STIR and 3D-SPACE images. Results: The thickness of …

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Can We Predict Patients That Will Not Benefit From Invasive Mechanical Ventilation? A Novel Scoring System In Intensive Care: The Imv Mortality Prediction Score (Impres), Tevfi̇k Özlü, Mehtap Pehli̇vanlar Küçük, Akin Kaya, Esra Yarar, Sami̇ Cenk Kirakli, Özlem Şengören Di̇ki̇ş, Hale Kefeli̇ Çeli̇k, Serdar Özkan, Hayri̇ye Bektaş Aksoy, Ahmet Oğuzhan Küçük Jan 2019

Can We Predict Patients That Will Not Benefit From Invasive Mechanical Ventilation? A Novel Scoring System In Intensive Care: The Imv Mortality Prediction Score (Impres), Tevfi̇k Özlü, Mehtap Pehli̇vanlar Küçük, Akin Kaya, Esra Yarar, Sami̇ Cenk Kirakli, Özlem Şengören Di̇ki̇ş, Hale Kefeli̇ Çeli̇k, Serdar Özkan, Hayri̇ye Bektaş Aksoy, Ahmet Oğuzhan Küçük

Turkish Journal of Medical Sciences

Background/aim: The present study aimed to define the clinical and laboratory criteria for predicting patients that will not benefit from invasive mechanical ventilation (IMV) treatment and determine the prediction of mortality and prognosis of these critical ill patients. Materials and methods: The study was designed as an observational, multicenter, prospective, and cross-sectional clinical study. It was conducted by 75 researchers at 41 centers in intensive care units (ICUs) located in various geographical areas of Turkey. It included a total of 1463 ICU patients who were receiving invasive mechanical ventilation (IMV) treatment. A total of 158 parameters were examined via logistic …

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Neutrophil-To-Lymphocyte Ratio, Monocyte-To-Lymphocyte Ratio, And Platelet-To-Lymphocyte Ratio In Different Etiological Causes Of Thyrotoxicosis, Işilay Taşkaldiran, Tülay Omma, Çağatay Emi̇r Önder, Sevde Nur Firat, Gönül Koç, Mustafa Kemal Kiliç, Şeri̇fe Mehli̇ka Kuşkonmaz, Cavi̇t Çulha Jan 2019

Neutrophil-To-Lymphocyte Ratio, Monocyte-To-Lymphocyte Ratio, And Platelet-To-Lymphocyte Ratio In Different Etiological Causes Of Thyrotoxicosis, Işilay Taşkaldiran, Tülay Omma, Çağatay Emi̇r Önder, Sevde Nur Firat, Gönül Koç, Mustafa Kemal Kiliç, Şeri̇fe Mehli̇ka Kuşkonmaz, Cavi̇t Çulha

Turkish Journal of Medical Sciences

Background/aim: The most common causes of thyrotoxicosis include Graves' disease (GD), toxic multinodular goiter (TMNG), toxic adenoma (TA), and subacute granulomatous thyroiditis (SAT). In our study, we aimed to see whether neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR), and mean platelet volume (MPV) may be helpful in the differential diagnosis of these diseases.Materials and methods: We retrospectively analyzed the hospital records of the Endocrinology Clinic of our hospital between 2016 and 2019. We included data from 66 GD, 37 TA, and 35 SAT patients. We compared the data with those of 35 healthy subjects as controls.Results: NLR, MLR, …

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Development And Psychometric Testing Of The Family Functioning Questionnaire In Rehabilitation (Ffqr), Hati̇ce Abaoğlu, Esra Aki Jan 2019

Development And Psychometric Testing Of The Family Functioning Questionnaire In Rehabilitation (Ffqr), Hati̇ce Abaoğlu, Esra Aki

Turkish Journal of Medical Sciences

Background/aim: The present study aimed to develop a reliable and valid assessment tool for measuring family functioning in rehabilitation. Materials and methods: Semistructured interviews were performed with 100 rehabilitation professionals working in pediatrics to identify the feature to be measured. The items determined with the qualitative analysis of the data were presented to 14 experts and content validity was provided. The questionnaire created based on the judgments of the experts was administered to 440 parents of children with special needs. Results: After validity and reliability analysis, the final version of the questionnaire comprised 48 items with four factors identified as …

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The Effect Of N-Acetylcysteine On Inflammation And Oxidative Stress In Cisplatin-Induced Nephrotoxicity: A Rat Model, İnayet Güntürk, Cevat Yazici, Sema Kader Köse, Fatma Dağli, Bi̇lal Yücel, Arzu Hanim Yay Jan 2019

The Effect Of N-Acetylcysteine On Inflammation And Oxidative Stress In Cisplatin-Induced Nephrotoxicity: A Rat Model, İnayet Güntürk, Cevat Yazici, Sema Kader Köse, Fatma Dağli, Bi̇lal Yücel, Arzu Hanim Yay

Turkish Journal of Medical Sciences

Background/Aim: Cisplatin is a highly effective chemotherapeutic agent used in the treatment of solid organ cancers. Besides its chemotherapeutic effectiveness, cisplatin administration is associated with numerous side effects. Of those, the most clinically significant and common effect is nephrotoxicity. Recent studies reported that oxidative stress and inflammation are probably the most important mechanisms that contribute to the nephrotoxicity. N-acetylcysteine (NAC) is an antioxidant and antiinflammatory agent. In the present study, the effects of NAC on cisplatin-induced nephrotoxicity were investigated. Materials and methods: Rats were divided into four groups each including eight rats: CONT, NAC-250, CP, and CP+NAC. Rats in experimental …

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Cover And Contents Jan 2019

Cover And Contents

Turkish Journal of Medical Sciences

No abstract provided.

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Radiographic Comparison Of Cervical Spine Motion Using Lma Fastrach, Lma Ctrach, And The Macintosh Laryngoscope, Gözde İnan, Nurdan Bedi̇rli̇, Zerri̇n Özköse Şatirlar Jan 2019

Radiographic Comparison Of Cervical Spine Motion Using Lma Fastrach, Lma Ctrach, And The Macintosh Laryngoscope, Gözde İnan, Nurdan Bedi̇rli̇, Zerri̇n Özköse Şatirlar

Turkish Journal of Medical Sciences

Background/aim: The optimal technique for airway management in patients with cervical pathology remains unclear. Intubating laryngeal mask airway devices such as LMA CTrach and LMA Fastrach have not been compared for cervical spine (C-spine) movements in the context of cervical pathology. The present study aimed to determine upper C-spine movements by radiography during intubation with different devices as well as comparing the duration and success of intubation in cervical surgery.Materials and methods: Sixty patients scheduled for elective cervical surgery were registered in this prospective, randomized study. Patients with cervical trauma/injury, previous neck surgery, and body mass index (BMI) of >35 …

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The Effect Of Hyperglycemic Peak Induced By Oral Glucose Tolerance Test On The Oxidant And Antioxidant Levels, Teki̇n Yildirim, Ayşe Yeşi̇m Göçmen, Zeynep Tuğba Özdemi̇r, Eli̇f Börekci̇, Eli̇f Turan, Yalçin Aral Jan 2019

The Effect Of Hyperglycemic Peak Induced By Oral Glucose Tolerance Test On The Oxidant And Antioxidant Levels, Teki̇n Yildirim, Ayşe Yeşi̇m Göçmen, Zeynep Tuğba Özdemi̇r, Eli̇f Börekci̇, Eli̇f Turan, Yalçin Aral

Turkish Journal of Medical Sciences

Background/aim: The possibility of adverse effects of the oral glucose tolerance test (OGTT) carried out for the screening of gestational diabetes among pregnant women and fetuses is a frequently discussed topic. The purpose of this study was to investigate the effects of the hyperglycemia peak during OGTT on the levels of oxidants and antioxidants in the body.Materials and methods: Eighty individuals who applied to the Outpatient Clinic with suspected diabetes and OGTT indication were included in the study. Glucose, total oxidant capacity status (TOS), total antioxidant capacity (TAS), superoxide dismutase (SOD), and lipid hydroperoxide (LOOH) levels were tested on blood …

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Role Of Aortic Stiffness And Inflammation In The Etiology Of Young-Onset Hypertension, Serkan Gökaslan, Çi̇ğdem Özer Gökaslan, Emi̇n Demi̇rel, Sefa Çeli̇k Jan 2019

Role Of Aortic Stiffness And Inflammation In The Etiology Of Young-Onset Hypertension, Serkan Gökaslan, Çi̇ğdem Özer Gökaslan, Emi̇n Demi̇rel, Sefa Çeli̇k

Turkish Journal of Medical Sciences

Background/aim: Young-onset hypertension is a form of condition diagnosed in patients aged below 40. Cytokines such as interleukin (IL)-6 and also MCP-1 may play a role in the development of arterial hypertension. Aortic stiffness can be detected by measuring pulse wave velocity (PWV). We aimed to explore the relationship between inflammation and aortic stiffness and investigate their roles in the etiology of young-onset hypertension.Materials and methods: We enrolled 16 patients diagnosed with young-onset hypertension and 16 volunteers without hypertension. The plasma levels of MCP-1 and IL-6 were determined using an enzyme-linked immunosorbent assay and quantitative enzyme-linked immunoassay, respectively. Carotid-femoral PWV …

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The Turkish Version Of The Modified Falls Efficacy Scale: Reliability And Validity From The Viewpoint Of Balance, Ni̇lüfer Çeti̇şli̇ Korkmaz, Mehmet Duray, Esra Doğru Hüzmeli̇, Hande Şenol Jan 2019

The Turkish Version Of The Modified Falls Efficacy Scale: Reliability And Validity From The Viewpoint Of Balance, Ni̇lüfer Çeti̇şli̇ Korkmaz, Mehmet Duray, Esra Doğru Hüzmeli̇, Hande Şenol

Turkish Journal of Medical Sciences

Background/aim: The factors associated with fall-related self-efficacy should be addressed, especially in the elderly. The Modified Falls Efficacy Scale (MFES) is a simple instrument with good scaling properties and reliability. The aim of the present study was to determine the reliability and the validity of the Turkish version of the MFES from the viewpoint of balance.Materials and methods: In this study, 164 participants aged >65 years were included. The use of walking aids and assistive devices, history and frequency of falls in the previous year, living environment, and exercise habits were noted. Balance and risk of falling were assessed with …

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Relationship Between Tissue And Serum Eosinophilia In Children Undergoing Adenotonsillectomy With Allergic Rhinitis, Nur Yücel Eki̇ci̇, Özgür Külahci Jan 2019

Relationship Between Tissue And Serum Eosinophilia In Children Undergoing Adenotonsillectomy With Allergic Rhinitis, Nur Yücel Eki̇ci̇, Özgür Külahci

Turkish Journal of Medical Sciences

Background/aim: Previous reports suggested that allergic/eosinophilic inflammation affects the adenoid and tonsillar tissue. The aim of this study is to evaluate and compare the tissue and serum eosinophilia in children undergoing adenotonsillectomy with allergic rhinitis.Materials and methods: The clinical registers of 125 children undergoing adenoidectomy/tonsillectomy due to adenoid/tonsil hypertrophy were examined and reviewed retrospectively. Fifty-seven children with positive skin prick test and symptoms of allergic rhinitis were included in the study as the atopic group, whereas 68 children with no allergic symptoms and negative skin prick test were included as the nonatopic group. Consequently, the total immunoglobulin E level and …

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Does Mammalian Target Of Rapamycin Or Sestrin 1 Protein Signaling Have A Role In Bone Fracture Healing?, Özhan Pazarci, Halef Okan Doğan, Seyran Kilinç, İsmet Yalkin Çamurcu Jan 2019

Does Mammalian Target Of Rapamycin Or Sestrin 1 Protein Signaling Have A Role In Bone Fracture Healing?, Özhan Pazarci, Halef Okan Doğan, Seyran Kilinç, İsmet Yalkin Çamurcu

Turkish Journal of Medical Sciences

Background/aim: Fracture healing is a complex physiological process that involves a well-orchestrated series of biological events. The mammalian target of rapamycin (mTOR) and sestrin 1 (SESN 1) play a central role in cell metabolism, proliferation, and survival. The aim of our study is to present serum mTOR and SESN 1 levels by comparing patients with or without bone fractures. It is also a guide for further research on the roles of these proteins in fracture healing. Materials and methods: A total of 34 patients (10 females, 24 males) with bone fractures and 32 controls (10 females, 22 males) participated in …

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Ifn-Γ Stimulated Dental Follicle Mesenchymal Stem Cells Regulate Activated Lymphocyte Response In Rheumatoid Arthritis Patients In Vitro, Noushin Zibandeh, Deni̇z Genç, Güzi̇de Nevsun İnanç, Rafi̇ Haner Di̇reskeneli̇, Tunç Akkoç Jan 2019

Ifn-Γ Stimulated Dental Follicle Mesenchymal Stem Cells Regulate Activated Lymphocyte Response In Rheumatoid Arthritis Patients In Vitro, Noushin Zibandeh, Deni̇z Genç, Güzi̇de Nevsun İnanç, Rafi̇ Haner Di̇reskeneli̇, Tunç Akkoç

Turkish Journal of Medical Sciences

Background/aim: Multipotent mesenchymal stem cells (MSCs) have been investigated in autoimmune diseases such as rheumatoid arthritis (RA) due to their immunomodulatory and regenerative properties. In this study, their immunosuppressive effects on peripheral blood mononuclear cells (PBMC) of RA patients were studied.Materials and methods: Dental follicle stem cells (DFSCs) were isolated from follicle tissue in the orofacial region. Characterization and multipotency analyses were performed. Lymphocytes were isolated from peripheral venous blood of RA patients (n = 5) and healthy individuals (n = 5). DFSCs were preincubated with IFN-γ for 48 h. PBMCs of RA patients and healthy individuals were separately cultured …

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The Impact Of Breeder Age On Egg Quality And Lysozyme Activity, Dorota Banaszewska, Barbara Biesiada-Drzazga, Dominik Ostrowski, Kamil Drabik, Justyna Batkowska Jan 2019

The Impact Of Breeder Age On Egg Quality And Lysozyme Activity, Dorota Banaszewska, Barbara Biesiada-Drzazga, Dominik Ostrowski, Kamil Drabik, Justyna Batkowska

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to analyze the biological components of eggs as well as lysozyme activity in relation to the age of hens. The research material consisted of eggs from parent stock of Ross 308 meat chickens. The eggs were evaluated at peak laying, i.e. eggs from 30-week-old hens, and after peak laying, i.e. from hens aged 60 weeks. Ninety eggs were evaluated in each period (180 eggs in total). Egg quality traits were divided into destructive and nondestructive traits. In addition, lysozyme activity in the albumen of the eggs was assessed. The quantitative characteristics of the eggs …

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Effect Of Various Antioxidants And Their Combinations On Bull Semen Cryopreservation, Şükrü Güngör, Ayhan Ata, Muhammed Enes İnanç, John P. Kastelic Jan 2019

Effect Of Various Antioxidants And Their Combinations On Bull Semen Cryopreservation, Şükrü Güngör, Ayhan Ata, Muhammed Enes İnanç, John P. Kastelic

Turkish Journal of Veterinary & Animal Sciences

Our objective was to evaluate the effects of adding 50 mM trehalose (TRE), 1 mM cysteine (CYS), or 400 µg catalase (CAT), individually or in combinations, to a Tris-based semen extender and determine the effects on fresh, chilled-equilibrated, and frozen-thawed bull sperm. Ejaculates from three Holstein bulls (1-3 years old) were pooled, divided into six equal portions, and put into a Tris-based extender supplemented with no additive (control), TRE, CYS, CAT, TRE + CYS, or TRE + CYS + CAT. In chilled-equilibrated semen, motility was highest in CAT but lowest in the control (P < 0.05). In thawed semen, motility was lower (P < 0.05) in CAT than in all other groups, which were not different. Based on a hypoosmotic swelling test (HOS test), TRE, CYS, and their combinations had higher (P < 0.05) percentages of sperm with an intact plasma membrane than the control or CAT groups. The TRE group had the least (P < 0.05) morphologically abnormal sperm. Plasma membrane and acrosomal integrity (PMAI) and high mitochondrial membrane potential (HMMP) values were highest in TRE and TRE + CYS and were lower (P < 0.05) in the control. Furthermore, HMMP was positively correlated with PMAI and HOS tests, but negatively correlated with major + minor abnormalities (r = 0.66, 0.242, and -0.349). In conclusion, the addition of TRE, with or without CYS, to a Tris-based semen extender improved several aspects of the frozen-thawed quality of bull semen. However, addition of CAT, by itself or in combination with other additives, did not protect bull sperm against cryopreservation-induced defects.

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Evaluation Of Passive Transfer In Goat Kids With Brix Refractometer And Comparison With Other Semiquantitative Tests, Hasan Batmaz, Yi̇ği̇t Kaçar, Onur Topal, Zafer Meci̇toğlu, Kadi̇r Semi̇h Gümüşsoy, Feyyaz Kaya Jan 2019

Evaluation Of Passive Transfer In Goat Kids With Brix Refractometer And Comparison With Other Semiquantitative Tests, Hasan Batmaz, Yi̇ği̇t Kaçar, Onur Topal, Zafer Meci̇toğlu, Kadi̇r Semi̇h Gümüşsoy, Feyyaz Kaya

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to evaluate the passive transfer (PT) status of goat kids by Brix refractometry and compare the results with other semiquantitative tests (total protein - TP, glutaraldehyde coagulation test - GCT, and gamma-glutamyltransferase - GGT) and immunoglobulin G (IgG). The study was conducted on 75 goat kids born from 47 Saanen goats. The blood samples were collected from the kids on day 0 (presuckling) and on the 1st, 2nd, and 3rd days after birth. The Brix% and TP concentrations were measured with refractometers, and GGT activity was measured using a dry chemistry system. The duration …

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Examining Stance Phases With The Help Of Infrared Optical Sensors In Horses, Ozan Gündemi̇r, Di̇lek Olğun Erdi̇kmen, Zi̇ynet Di̇la Ateşpare, Kozet Avanus Jan 2019

Examining Stance Phases With The Help Of Infrared Optical Sensors In Horses, Ozan Gündemi̇r, Di̇lek Olğun Erdi̇kmen, Zi̇ynet Di̇la Ateşpare, Kozet Avanus

Turkish Journal of Veterinary & Animal Sciences

The purpose of the present study was to examine the walking phases in horses using the OptoGait system, which works with optical sensors. In this pilot study, 52 healthy horses were used. For each horse, an average of 45 steps were examined. The stance phase, swing phase, step distance, and walking speeds of the horses were recorded. The stance phase of each step was examined in a separate manner in 3 steps: contact phase, foot flat, and propulsive phase. The contact phase and the propulsive phase of the forelimb and hind limb were significantly different. The propulsive phase was significantly …

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Ethnoveterinary Medicine In Turkey: A Comprehensive Review, Zeynep Büşra Erarslan, Şükran Kültür Jan 2019

Ethnoveterinary Medicine In Turkey: A Comprehensive Review, Zeynep Büşra Erarslan, Şükran Kültür

Turkish Journal of Veterinary & Animal Sciences

Today, traditional societies throughout the world possess a wealth of ethnoveterinary knowledge, which they have accumulated during prolonged interaction with nature. Turkey has ample resources of ethnoveterinary medicines as evident from its rich floral diversity and traditional botanical knowledge from the past. This review aims to compile herbal remedies used in ethnoveterinary medicine in Turkey with comprehensive usage information and to compare our findings with pharmacological studies. The botanical, family, and local names; used parts; preparation methods; administration/dosage and duration of the treatment; and ailments treated/therapeutic effects were presented by screening ethnobotanical and ethnoveterinary studies. The most cited plant families, …

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