Digital Commons Network^™

The Lived Experience Of Work And Career Among Individuals With Bipolar Disorder: A Phenomenological Study Of Discussion Forum Narratives, Susan R. Rathbun-Grubb

Faculty Publications

Individuals with invisible chronic illnesses are often at a disadvantage in the workplace in terms of job security, promotion, and occupational success. Because little is known about the use of public online support forums to help patients with mental health disorders cope with the impact their illness has on their work and career, this research identifies and examines online forum posts related to employment by contributors with bipolar disorder. Seven percent of the total eligible posts from four discussion forums (n = 7,712) contained mentions of work and career (n = 572). A thematic analysis of the 572 posts is …

"Like Two Beach Umbrellas Put Together": Investigating The Health Information Practices Of South Carolina Lgbtq+ Communities, Vanessa Kitzie, Travis L. Wagner, Valerie A. Lookingbill, Alexander N. Vera

Faculty Publications

This poster presents initial findings from an exploratory, qualitative study investigating the health information practices of LGBTQ+ communities in South Carolina (SC). Significant health disparities exist between LGBTQ+ people and their cisgender, heterosexual counterparts. An important but under-researched barrier producing disparities is informational, as LGBTQ+ people face challenges in learning about their healthcare needs, navigating the healthcare system, and overcoming barriers to care. This study addresses research gaps via the following questions: 1) How do LGBTQ+ communities create, seek, share, and use health information?, and 2) What social and structural factors affect these health-related information practices?Findings are informed by ~30 …

Resituating Public Library Values To Leverage The Health Information Practices Of South Carolina Lgbtq+ Communities, Vanessa Kitzie, Travis L. Wagner, Alexander N. Vera, Valerie A. Lookingbill

Faculty Publications

No abstract provided.

We Try To Find Something For Whatever Obstacle Might Be In Our Way": Understanding The Health Information Practices Of South Carolina Lgbtq+ Communities, Vanessa Kitzie, Travis L. Wagner, Valerie A. Lookingbill, Alexander N. Vera

Faculty Publications

Title: “We Try to Find Something for Whatever Obstacle Might be in Our Way”: Understanding the Health Information Practices of South Carolina LGBTQ+ Communities Objective: LGBTQ+ people experience health disparities compared to heterosexual, cisgender peers. Individual and systemic barriers produe these disparities. One barrier is informational, as LGBTQ+ people experience challenges when learning about their health needs, navigating the healthcare system, and overcoming obstacles to care. This paper investigates the future of libraries and the health sciences by exploring how they can address these informational barriers. Methods: This paper reports on ~30 ongoing interviews with LGBTQ+ community leaders from South …

A Knowledge Lens: Humans In Action, Darin S. Freeburg

Faculty Publications

Every member of a social system sees that system in a particular way. This essay outlines a

new way of seeing the uniquely human characteristics in these systems, with particular attention to what happens when this view is taken. Termed the Knowledge Lens, this view embraces complexity, sees the potential of innovation through conversation, and understands the barriers limiting the traditionally assumed powers of data, information, and knowledge. This lens is approached within the context of ensuring that graduates of a Knowledge School are equipped with the tools and understanding necessary to facilitate positive change and increase human agency--both in …

Culture And Heritage: A Foundation For Sustainable Development Through Understanding And Tolerance Of Cultural Differences, Melodena Stephens, Shamma Bint Sultan Bin Khalifa Al Nahyan, Frederik Panz, Filareti Kotsi

All Works

No abstract provided.

Coming Of Age In The Rio Grande Valley: Race, Class, Gender, And Generations In Narco Culture, Rosalynn A. Vega

Anthropology Faculty Publications

Based on ethnographic observations in the Rio Grande Valley of South Texas, this article examines the multiple, overlapping, criss-crossing axes of inequality that both shape and fracture the experiences of individual borderland residents. Instead of focusing on the national border, this article analyzes intersecting axes of social inequality and uses ethnographic data to describe social borders that divide and separate those living in the borderlands. Using ethnographic data culled from 133 young adults in focus group settings, this article merges the theory of intersectionality with border studies scholarship in order to analyze how socio-economic stratification, gender inequality, histories of racial …

Justice Kennedy And The First Amendment, David L. Hudson Jr.

Law Faculty Scholarship

This essay reviews some of Justice Anthony Kennedy’s most significant contributions to First Amendment jurisprudence. These include his calls for absolute protection for pure political speech, his strong protection for commercial speech, his distaste for campaign finance reform laws that censored speech, his general concern for the silencing of sexual expression, his coercion test in Establishment Clause cases, and his significant failure in the public-employee free-speech decision Garcetti v. Ceballos.

The Popular Constitutional Canon, Thomas G. Donnelly

Law Faculty Publications

Popular constitutionalism scholarship has often left out the American people. Sure, ordinary citizens make cameo appearances—often through the actions of elected officials and elite movement leaders. However, focusing on high politics among elite actors—even if those actors are not judges—simply is not enough. If popular constitutional views do, indeed, matter, then we can expect constitutional partisans to try to manipulate the processes through which these views emerge. Some constitutional scholars have made a start, reflecting on the importance of the constitutional canon. However, these scholars focus mostly on the legal canon and often ignore its popular analog. At the same …

Copyrights In Higher Education: Motivating A Research Agenda, Jacob H. Rooksby

Law Faculty Publications

The Bayh–Dole Act of 1980 enabled American universities to engage in technology transfer. Thirty years of research has investigated the legislation’s effectiveness and derivative university practices, such as the establishment of technology transfer offices. Unfortunately, the technology transfer literature has focused primarily on patenting as the primary transfer vehicle for protecting intellectual property in universities, overlooking other forms of IP ownership, such as copyrights. Legal scholarship shows, however, that universities are increasingly using copyrights to protect their intellectual property and that the number of university-held copyrights exceeds patents. This paper examines the use of copyrights to protect and transfer university …

Unjust Timing Limitations In Genetic Malpractice Cases, Lauren E. Clatch

Law Faculty Publications

As genomic data are increasingly being collected and applied in clinical care, physicians, laboratories, and other health care providers are more frequently being sued for alleged medical malpractice or negligence. Because the genetic underpinnings of an existing or future health condition may not be immediately apparent, such cases sometimes raise unique timing issues involving the applicable statute of limitations, statute of repose, or statutory notification requirements. Although these timing limitations on when a lawsuit can be brought have important policy rationales and justifications, such as helping to protect providers from open-ended liability, their application to genetic liability cases may sometimes …

Catalog 2019-2020, University Of North Florida

UNF Course Catalogs

No abstract provided.

Policies And Procedures Perceived By School Leaders To Reduce Truancy In A Public Charter School, Alix Desulme

All Theses And Dissertations

This qualitative study examined the causes of student truancy and the policies and procedures established by one public charter school to reduce truancy. Eight participants were asked to discuss the policies and procedures of their school, CSS, and how they as school leaders contributed to the success of the school regarding low truancy rates. Student truancy has become a major concern in the United States with some states and some counties experiencing higher truancy rates than others. This study aimed to understand leaders’ perceptions of the effectiveness of truancy policies at their school. To understand what factors affected truancy at …

"Cyborg Justice" And The Risk Of Technological-Legal Lock-In, Rebecca Crootof

Law Faculty Publications

Although Artificial Intelligence (AI) is already of use to litigants and legal practitioners, we must be cautious and deliberate in incorporating AI into the common law judicial process. Human beings and machine systems process information and reach conclusions in fundamentally different ways, with AI being particularly ill-suited for the rule application and value balancing required of human judges. Nor will “cyborg justice”—hybrid human/AI judicial systems that attempt to marry the best of human and machine decisionmaking and minimize the drawbacks of both—be a panacea. While such systems would ideally maximize the strengths of human and machine intelligence, they might also …

Reflections On A Law Teaching Career As The Curtain Closes Only To Open Again, Jonathan K. Stubbs

Law Faculty Publications

Grandmother once said to me, "Johnny boy, it ain't as long as it has been." Stated another way, Grandma was telling me that there were not as many years to come in her life as had already passed. In some respects, that's the way it is with one's teaching career. There is a beginning, a middle, and then a "something else." I write to briefly share a few personal comments regarding how I am thinking about what happens next in my evolving career. [..]

Ecological Risk Assessment Of Heavy Metals In Soils From An Informal E-Waste Dismantling Site, Buriram Province, Thailand, Nisakorn Amphalop

Chulalongkorn University Theses and Dissertations (Chula ETD)

The research aimed to investigate the contamination and fractionations, and evaluate the ecological risk posed by heavy metals in the e-waste site in Daeng Yai and Ban Pao e-waste dismantling sites, Buriram Province, Thailand. The soil samples were taken from e-waste houses (EW), and e-waste open-burning sites (OB) as representatives of the e-waste sites, while soils from paddy fields (PF), non-e-waste houses, and groundwater wells represented the surrounding area, and the reference site was located 5 km away from the e-waste dismantling site. The soil samples were digested by aqua regia by the microwave digester for total heavy metal determination, …

Enrichment, Characterization And Application Of Bacterial Consortia For Degrading 2-Mercaptobenzothiazole In Rubber Processing Wastewater, Saowaluk Krainara

Chulalongkorn University Theses and Dissertations (Chula ETD)

Benzothiazoles is widely used as vulcanized accelerator in rubber industry. The high volume of 2-MBT usages resulted in its release into the environment and can cause adverse health impacts. This study aimed to obtain efficient 2-MBT-degrading bacteria for wastewater application. The bacterial consortia were enriched by incubating rubber wastewater sludge in a medium containing 2-MBT for 28 days followed by a stepwise acclimation by gradually increasing 2-MBT concentrations in an NH4Cl-containing medium for 76 days. The process significantly increased the bacterial number and changed the dominant populations and degradative genes. Among these consortia, the EN consortium had the highest specific …

Selective Oxidation Of H2s In Biogas To Sulfur On V2o5 Catalyst Dispersedon Ceo2-Mo2 (M = Ti, Si, Zr) Mixed Oxides, Benjamaporn Tudkesorn

Chulalongkorn University Theses and Dissertations (Chula ETD)

In this research, the characteristics and catalytic performances of V2O5catalysts supported on mixed oxides CeO2-MO2 (M = Ti, Si, Zr) as compared to the commercial CeO2 supported ones were studied in the selective catalytic oxidation of H2S in biogas to sulfur at 130oC. The mixed-oxide supports were prepared by co-precipitation method with 3 wt.% vanadium loading by wet impregnation method. From the XRD and Raman spectroscopy results, all the catalysts exhibited high dispersion of V2O5 on the supports with the 1:1 molar ratio CeO2-SiO2 mixed oxide showed the highest conversion of H2S at ̴ 73% and low selectivity of SO2 …

Comparative Study On The Effectiveness Of Myofunctional Therapy Of The Tongue After Frenectomy In Ankyloglossia, Nattakarn Povichit

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: This study's objective of was investigate the effectiveness of myotherapy on tongue mobility and tongue function after surgical correction in ankyloglossia. Method: This study was carried out in 15 subjects assigned to the control group (n=5). The other 10 individuals with ankyloglossia were randomly received frenectomy alone (F; n=5) and frenectomy performed with tongue myofunctional therapy (FM; n=5). Tongue myofunctional therapy was performed 1 day after surgery, and 3 times a day for 3 months. Age, gender, height, weight, IBM, Kotlow's free tongue movement, maximal interincisal mouth opening (MIO), interincisal mouth opening with tongue tip to maxillary incisive papillae …

Evaluation Of Maxillary Sinus On Anatomical Characteristics And Related Factors Using Cone Beam Computed Tomography Images, Nutcha Benjaphalakron

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objective: The aim of this study was to evaluate prevalence of the anatomical characteristics in maxillary sinuses; and its association with sex, age, tooth area and dental status using cone beam computed tomography (CBCT). Methods: Retrospectively reviewed CBCT images of maxillary sinuses from 370 sinuses in 185 patients at the Faculty of Dentistry, Chulalongkorn University were evaluated. Residual ridge height (RRH), lateral wall thickness (LWT), sinus septa, posterior superior alveolar artery (PSAA), membrane thickness (MT) and ostium were evaluated and compared according to sex, age, tooth area and dental status. Results: Mean RRH was 12.13 ± 3.64 mm. Mean LWT …

Development Of Cell-Penetrating Peptides Targeting Nuclear And Extra-Nuclear Signaling Pathways In Cancer Cells, Panthita Kaewjanthong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Growth factors and hormones often mediate their biological effects through series of protein-protein interaction between cytoplasmic signaling molecules or transcription factors. Interfering of these protein-protein interactions has been shown to reduce or inhibit biological and growth responses to various growth factors and hormones. We previously demonstrated that progesterone receptor (PR) contains a polyproline domain (PPD) which directly interact to Src homology 3 (SH3) domain-containing molecules and expression of PR-PPD inhibits EGFR-mediated NSCLC cell proliferation. In this study, we investigated that the introduction of PR-PPD by cell-penetrating peptide could inhibit EGF-induced NSCLC cell proliferation. PR-PPD was attached to a cancer-specific CPP, …

Roles Of Lin28 Proteins In Cholangiocarcinoma, Nattapong Puthdee

Chulalongkorn University Theses and Dissertations (Chula ETD)

LIN28 is an RNA-binding protein, a known as regulator of microRNAs biogenesis and play a role in multiple cellular functions such as stem cell maintenance, cell metabolism and implicated in oncogenesis. In cancer study, LIN28 protein is frequently expressed and associated with tumor aggressiveness and poor disease outcome. Previous studies have shown that paralog-LIN28B was upregulated in during CCA development. However, the role of LIN28B in cholangiocarcinogenesis remains largely unknown. The present study, we found LIN28B is overexpressed in CCA patients' tissues. Overexpression of LIN28B in cholangiocytes-MMNK-1 cells showed that LIN28B enhanced cell proliferation, clonogenic potential, and promoted epithelial-to mesenchymal …

Cyp3a And Drug Transporters Activity Changes In Thai Elderly With Or Without Chronic Kidney Disease Using A Microdose Cocktail, Punyabhorn Rattanacheeworn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Thai general population has become more “aged society” (>60 years old) and chronic kidney disease (CKD) is one of major public health problems in Thailand. Ageing and CKD are known to affect pharmacokinetics which generally determines drug exposure in plasma and site of action. Due to the related mechanisms are still unclear, cytochrome P450 (CYP)3A and drug transporters activity changes were investigated in Thai elderly with or without CKD compared to healthy adults using a microdose cocktail. This study was conducted in 3 groups of subjects: Group 1, healthy young subjects; Group 2, healthy elderly subjects; Group 3; elderly …

Development Of Niosome Containing Ace Inhibitor/Cyclodextrin Complexes As An Ophthalmic Delivery For Lowering Intraocular Pressure, Hay Marn Hnin

Chulalongkorn University Theses and Dissertations (Chula ETD)

The purpose of this study was to develop a stable niosomal eye drop containing angiotensin converting enzyme (ACE) inhibitor for lowering intraocular pressure. Three ACE inhibitors i.e., captopril, quinapril and fosinopril (FOS) were used in this study. Their inclusion complexes formation with parent CDs i.e., alphaCD, betaCD and gammaCD were determined. All drugs represented 1:1 stoichiometry inclusion complex with each CD. Of these, FOS/gammaCD complex showed the highest stability constant. Kinetic degradation study confirmed that FOS showed the lowest degradation in the presence of gammaCD. The obtained results of solution- and solid-state characterizations including molecular docking supported the true inclusion …

Development And Optimization Of Self-Microemulsifying Astaxanthin Delivery System Using The Design Of Experiment (Doe) Approach, Mo Mo Ko Zin

Chulalongkorn University Theses and Dissertations (Chula ETD)

The purpose of this research was to develop and optimize a self-microemulsifying delivery system (SMEDS) to improve dissolution rate of poor soluble compound AST by mixture experimental design. The solubility of AST was analyzed with various excipients so that the appropriate oil, surfactant, and cosurfactant were figured out. Through the findings about the microemulsion existence area, the pseudoternary phase diagrams were constructed for selecting the optimum combination of excipients in a formulation of SMEDS. The optimized LCT-SMEDS obtained from the design space was composed of 19.59% castor oil (oil; X1), 62.34% Cremophor® RH 40 (surfactant; X2), and 18.03% Tween® 80 …

Chemical Modifications Of Α-Mangostin For Cytotoxic Study On Lung Cancer Cell Lines, Nan Yadanar Lin Pyae

Chulalongkorn University Theses and Dissertations (Chula ETD)

α-Mangostin is a natural oxygenated and prenylated xanthone, which is mainly isolated from the pericarps of Garcinia mangostana. It possesses numerous pharmacological properties and promising therapeutic effects. However, the limitations of α-mangostin such as highly hydrophobicity and poor bioavailability hider its therapeutic applications. To overcome these drawbacks of α-mangostin, chemical modifications have been performed to discover the improved analogs. Herein, two semi-synthetic approaches to obtain new α-mangostin derivatives were investigated by the modifications of the phenolic hydroxy groups at C-3 and C-6 positions involving Smiles rearrangement to install amine functional groups and the addition reaction of isocyanate to form the …

Method Development For Determination Of Ss-Agonists Using Colorimetric And Electrochemical Sensors, Atchara Lomae

Chulalongkorn University Theses and Dissertations (Chula ETD)

This dissertation focused on the development of analytical sensors for quantitative analysis of various electroactive compounds such as β-agonists and neurotransmitters, which could be considered as important indicators for food-safety monitoring, drug doping control in sports, clinical testing, and health care inspection. Up to date, colorimetry and electrochemistry are the two attractive approaches that have extensively been employed as analytical sensing tools, due to their simple operation and interpretation, fast analysis time, good ability of coupling with other techniques, and high capability of miniaturization. With these two detection platforms, this dissertation would then be divided into two main parts: (1) …

Facial Features Detection System For Classifying Critical Situation Of Brain Surgery Postoperative Patients, Bhatarasiri Slakkham

Chulalongkorn University Theses and Dissertations (Chula ETD)

The purpose of this research is to create a model for detecting a help signal from stroke patients after surgery. Through artificial intelligence technology by detecting via a patient's face image to help reducing workload and hospital’s expenses. The data is collected from the Stroke Unit, King Chulalongkorn Memorial Hospital at the intensive care unit (ICU). The total number of samples is 8 persons, all these 8 were screened by the doctor and completed the consent forms before data being collected. The method of data collection is performed by attaching 3 small cameras on three positions: the left, right and …

Genetic And Pathogenic Characterizations Of Newly Emerged Duck Tembusu Virus Isolated In Thailand, Patchareeporn Ninvilai

Chulalongkorn University Theses and Dissertations (Chula ETD)

Duck Tembusu virus (DTMUV), a mosquito-borne Flavivirus, caused an emerging disease in ducks in Asia since 2010, resulting in significant economic loss in duck producing industry. After the initial outbreak in 2013, DTUMV cases have been continuously detected in several duck farms in Thailand. Thus, the disease surveillance and the genetic characterization of the Thai DTMUV are necessary. Therefore, the first objective of this dissertation was to investigate the genetic characteristic of DTMUVs circulating in Thailand. Our retrospective study demonstrated the presence of DTMUV in the Thai ducks since 2007. Phylogenetic analysis of the polyprotein gene sequence revealed that the …

Spatial And Temporal Variation Of Heavy Metals In Pm10 And Pm2.5 Surrounding E-Waste Dismantling Community In Buriram Province, Siriwipha Chanthahong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Spatial and temporal variation of heavy metals in PM10 and PM2.5 surrounding e-waste dismantling community at Buriram Province were investigated during April and September. The aims of this study were to monitor and compare between those found at non- (NS) and e-waste dismantling house (ES) and open dump area (OD), and identify potential sources of heavy metals including As, Cr, Cu, Cd, Ni, Mn, Pb, Zn and Fe. The heavy metals in PM were analyzed by ICP-MS. The results showed that average PM2.5 and PM10 were highest at NS (33.8 ±18.8 µg/m3) and OD (57.6 ±17.5 µg/m3), respectively. PM2.5 was …