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2019

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The Rationale, Design, And Methods Of A Randomized, Controlled Trial To Evaluate The Efficacy And Safety Of An Active Strategy For The Diagnosis And Treatment Of Acute Pulmonary Embolism During Exacerbations Of Chronic Obstructive Pulmonary Disease, Roger Yusen, Slice Investigators, Et Al Jan 2019

The Rationale, Design, And Methods Of A Randomized, Controlled Trial To Evaluate The Efficacy And Safety Of An Active Strategy For The Diagnosis And Treatment Of Acute Pulmonary Embolism During Exacerbations Of Chronic Obstructive Pulmonary Disease, Roger Yusen, Slice Investigators, Et Al

Open Access Publications

No abstract provided.


Comparison Of The Pharmacokinetic Properties Of Triamcinolone And Dexamethasone For Local Therapy Of The Inner Ear, Alec Nicholas Salt, Jared James Hartsock, Jennifer Hou, Fabrice Piu Jan 2019

Comparison Of The Pharmacokinetic Properties Of Triamcinolone And Dexamethasone For Local Therapy Of The Inner Ear, Alec Nicholas Salt, Jared James Hartsock, Jennifer Hou, Fabrice Piu

Open Access Publications

No abstract provided.


Chronic Ly49h Receptor Engagement In Vivo Decreases Nk Cell Response To Stimulation Through Itam-Dependent And Independent Pathways Both In Vitro And In Vivo, Phillip N. Key, Joe Germino, Liping Yang, Sytse J. Piersma, Sandeep K. Tripathy Jan 2019

Chronic Ly49h Receptor Engagement In Vivo Decreases Nk Cell Response To Stimulation Through Itam-Dependent And Independent Pathways Both In Vitro And In Vivo, Phillip N. Key, Joe Germino, Liping Yang, Sytse J. Piersma, Sandeep K. Tripathy

Open Access Publications

No abstract provided.


Treatment, Complications, And Outcomes Of Metastatic Disease Of The Spine: From Patchell To Promis, Alexander T. Yahanda, Jacob M. Buchowski, Adam M. Wegner Jan 2019

Treatment, Complications, And Outcomes Of Metastatic Disease Of The Spine: From Patchell To Promis, Alexander T. Yahanda, Jacob M. Buchowski, Adam M. Wegner

Open Access Publications

No abstract provided.


Shared Cell Of Origin In A Patient With Erdheim-Chester Disease And Acute Myeloid Leukemia, Armin Ghobadi, Christopher A. Miller, Tiandao Li, Michelle O'Laughlin, Yi-Shan Lee, Mohga Ali, Peter Westervelt, John F. Dipersio, Lukas Wartman Jan 2019

Shared Cell Of Origin In A Patient With Erdheim-Chester Disease And Acute Myeloid Leukemia, Armin Ghobadi, Christopher A. Miller, Tiandao Li, Michelle O'Laughlin, Yi-Shan Lee, Mohga Ali, Peter Westervelt, John F. Dipersio, Lukas Wartman

Open Access Publications

No abstract provided.


Genetic Variation Across Rna Metabolism And Cell Death Gene Networks Is Implicated In The Semantic Variant Of Primary Progressive Aphasia, Celeste M. Karch, Natalie L. Wen, Et Al. Jan 2019

Genetic Variation Across Rna Metabolism And Cell Death Gene Networks Is Implicated In The Semantic Variant Of Primary Progressive Aphasia, Celeste M. Karch, Natalie L. Wen, Et Al.

Open Access Publications

No abstract provided.


A Comparison Of Shallow And Deep Learning Methods For Predicting Cognitive Performance Of Stroke Patients From Mri Lesion Images, Sucheta Chauhan, Lovekesh Vig, Michele De Filippo De Grazia, Maurizio Corbetta, Shandar Ahmad, Marco Zorzi Jan 2019

A Comparison Of Shallow And Deep Learning Methods For Predicting Cognitive Performance Of Stroke Patients From Mri Lesion Images, Sucheta Chauhan, Lovekesh Vig, Michele De Filippo De Grazia, Maurizio Corbetta, Shandar Ahmad, Marco Zorzi

Open Access Publications

No abstract provided.


A Meta-Analysis Of Genome-Wide Association Studies Identifies Multiple Longevity Genes, Mary K. Wojczynski, Michael A. Province, Et Al. Jan 2019

A Meta-Analysis Of Genome-Wide Association Studies Identifies Multiple Longevity Genes, Mary K. Wojczynski, Michael A. Province, Et Al.

Open Access Publications

No abstract provided.


Patients With Endometrial Cancer Continue To Lack Understanding Of Their Risks For Cancer, Subhjit Sekhon, L. Stewart Massad, Andrea R. Hagemann, Rebecca Dick, Andrea Leon, Abigail S. Zamorano, Premal H. Thaker, Carolyn K. Mccourt, David G. Mutch, Matthew A. Powell, Lindsay M. Kuroki Jan 2019

Patients With Endometrial Cancer Continue To Lack Understanding Of Their Risks For Cancer, Subhjit Sekhon, L. Stewart Massad, Andrea R. Hagemann, Rebecca Dick, Andrea Leon, Abigail S. Zamorano, Premal H. Thaker, Carolyn K. Mccourt, David G. Mutch, Matthew A. Powell, Lindsay M. Kuroki

Open Access Publications

No abstract provided.


Communication Interventions In Adult And Pediatric Oncology: A Scoping Review And Analysis Of Behavioral Targets, Bryan A. Sisk, Ginny L. Schulz, Jennifer W. Mack, Lauren Yaeger, James Dubois Jan 2019

Communication Interventions In Adult And Pediatric Oncology: A Scoping Review And Analysis Of Behavioral Targets, Bryan A. Sisk, Ginny L. Schulz, Jennifer W. Mack, Lauren Yaeger, James Dubois

Open Access Publications

No abstract provided.


Clinical Impact Of An Antimicrobial Stewardship Program On High-Risk Pediatric Patients, Jennifer L. Goldman, Jason G. Newland, Michael Prince, Diana Yu, Brian R. Lee Jan 2019

Clinical Impact Of An Antimicrobial Stewardship Program On High-Risk Pediatric Patients, Jennifer L. Goldman, Jason G. Newland, Michael Prince, Diana Yu, Brian R. Lee

Open Access Publications

No abstract provided.


Inhaled Gm-Csf In Neonatal Mice Provides Durable Protection Against Bacterial Pneumonia, Elizabeth M. Todd, Rashmi Ramani, Taylor P. Szasz, S. Celeste Morley Jan 2019

Inhaled Gm-Csf In Neonatal Mice Provides Durable Protection Against Bacterial Pneumonia, Elizabeth M. Todd, Rashmi Ramani, Taylor P. Szasz, S. Celeste Morley

Open Access Publications

No abstract provided.


Dermal And Muscle Fibroblasts And Skeletal Myofibers Survive Chikungunya Virus Infection And Harbor Persistent Rna, Alissa R. Young, Marissa C. Locke, Lindsey E. Cook, Bradley E. Hiller, Rong Zhang, Matthew L. Hedberg, Kristen J. Monte, Deborah J. Veis, Michael J. Diamond, Deborah J. Lenschow Jan 2019

Dermal And Muscle Fibroblasts And Skeletal Myofibers Survive Chikungunya Virus Infection And Harbor Persistent Rna, Alissa R. Young, Marissa C. Locke, Lindsey E. Cook, Bradley E. Hiller, Rong Zhang, Matthew L. Hedberg, Kristen J. Monte, Deborah J. Veis, Michael J. Diamond, Deborah J. Lenschow

Open Access Publications

No abstract provided.


Desmin Forms Toxic, Seeding-Competent Amyloid Aggregates That Persist In Muscle Fibers, Niraja Kedia, Khalid Arhzaouy, Sara K. Pittman, Yuanzi Sun, Mark Batchelor, Conrad C. Weihl, Jan Bieschke Jan 2019

Desmin Forms Toxic, Seeding-Competent Amyloid Aggregates That Persist In Muscle Fibers, Niraja Kedia, Khalid Arhzaouy, Sara K. Pittman, Yuanzi Sun, Mark Batchelor, Conrad C. Weihl, Jan Bieschke

Open Access Publications

No abstract provided.


Bogotá River Anthropogenic Contamination Alters Microbial Communities And Promotes Spread Of Antibiotic Resistance Genes, Carlos Eduardo Posada-Perlaza, Adán Ramírez-Rojas, Paola Porras, Boahemaa Adu-Oppong, Ana-María Botero-Coy, Félix Hernández, Juan M. Anzola, Lorena Díaz, Gautam Dantas, Alejandro Reyes, María Mercedes Zambrano Jan 2019

Bogotá River Anthropogenic Contamination Alters Microbial Communities And Promotes Spread Of Antibiotic Resistance Genes, Carlos Eduardo Posada-Perlaza, Adán Ramírez-Rojas, Paola Porras, Boahemaa Adu-Oppong, Ana-María Botero-Coy, Félix Hernández, Juan M. Anzola, Lorena Díaz, Gautam Dantas, Alejandro Reyes, María Mercedes Zambrano

Open Access Publications

No abstract provided.


Indirect Cost Of Traumatic Brachial Plexus Injuries In The United States, Thomas S. Hong, Andrea Tian, Ryan Sachar, Wilson Z. Ray, David M. Brogan, Christopher J. Dy Jan 2019

Indirect Cost Of Traumatic Brachial Plexus Injuries In The United States, Thomas S. Hong, Andrea Tian, Ryan Sachar, Wilson Z. Ray, David M. Brogan, Christopher J. Dy

Open Access Publications

No abstract provided.


Optimizing Efficiency And Safety In External Beam Radiotherapy Using Automated Plan Check (Apc) Tool And Six Sigma Methodology, Shi Liu, Karl K. Bush, Julian Bertini, Yabo Fu, Jonathan M. Lewis, Daniel J. Pham, Yong Yang, Thomas R. Niedermayr, Lawrie Skinner, Lei Xing, Beth M. Beadle, Annie Hsu, Nataliya Kovalchuk Jan 2019

Optimizing Efficiency And Safety In External Beam Radiotherapy Using Automated Plan Check (Apc) Tool And Six Sigma Methodology, Shi Liu, Karl K. Bush, Julian Bertini, Yabo Fu, Jonathan M. Lewis, Daniel J. Pham, Yong Yang, Thomas R. Niedermayr, Lawrie Skinner, Lei Xing, Beth M. Beadle, Annie Hsu, Nataliya Kovalchuk

Open Access Publications

No abstract provided.


A Regulatory Variant Of Chrm3 Is Associated With Cannabis-Induced Hallucinations In European Americans, Zhongshan Cheng, Chureerat Phokaew, Yi-Ling Chou, Dongbing Lai, Jacquelyn L. Meyers, Arpana Agrawal, Lindsay A. Farrer, Henry R. Kranzler, Joel Gelernter Jan 2019

A Regulatory Variant Of Chrm3 Is Associated With Cannabis-Induced Hallucinations In European Americans, Zhongshan Cheng, Chureerat Phokaew, Yi-Ling Chou, Dongbing Lai, Jacquelyn L. Meyers, Arpana Agrawal, Lindsay A. Farrer, Henry R. Kranzler, Joel Gelernter

Open Access Publications

No abstract provided.


Modelling Resilience In Adolescence And Adversity: A Novel Framework To Inform Research And Practice, Gin S. Malhi, Pritha Das, Erica Bell, Greg Mattingly, Zola Mannie Jan 2019

Modelling Resilience In Adolescence And Adversity: A Novel Framework To Inform Research And Practice, Gin S. Malhi, Pritha Das, Erica Bell, Greg Mattingly, Zola Mannie

Open Access Publications

No abstract provided.


Whole-Cortex Mapping Of Common Genetic Influences On Depression And A Social Deficits Dimension, Alexander S. Hatoum, Andrew E. Reineberg, Harry R. Smolker, John K. Hewitt, Naomi P. Friedman Jan 2019

Whole-Cortex Mapping Of Common Genetic Influences On Depression And A Social Deficits Dimension, Alexander S. Hatoum, Andrew E. Reineberg, Harry R. Smolker, John K. Hewitt, Naomi P. Friedman

Open Access Publications

No abstract provided.


Multi-Ancestry Sleep-By-Snp Interaction Analysis In 126,926 Individuals Reveals Lipid Loci Stratified By Sleep Duration, Raymond Noordam, Yun Ju Sung, Karen Schwander, Lisa De Las Fuentes, Treva K. Rice, Dabeeru C. Rao, Mary Feitosa, Aldi Kraja, Mike Province, Et Al. Jan 2019

Multi-Ancestry Sleep-By-Snp Interaction Analysis In 126,926 Individuals Reveals Lipid Loci Stratified By Sleep Duration, Raymond Noordam, Yun Ju Sung, Karen Schwander, Lisa De Las Fuentes, Treva K. Rice, Dabeeru C. Rao, Mary Feitosa, Aldi Kraja, Mike Province, Et Al.

Open Access Publications

No abstract provided.


Allogeneic Transplantation In Elderly Patients ≥65 Years With Non-Hodgkin Lymphoma: A Time-Trend Analysis, Nirav N. Shah, Ravi Vij, Et Al. Jan 2019

Allogeneic Transplantation In Elderly Patients ≥65 Years With Non-Hodgkin Lymphoma: A Time-Trend Analysis, Nirav N. Shah, Ravi Vij, Et Al.

Open Access Publications

No abstract provided.


End Points For Sickle Cell Disease Clinical Trials: Renal And Cardiopulmonary, Cure, And Low-Resource Settings, Ann T. Farrell, Shalini Shenoy, Et Al. Jan 2019

End Points For Sickle Cell Disease Clinical Trials: Renal And Cardiopulmonary, Cure, And Low-Resource Settings, Ann T. Farrell, Shalini Shenoy, Et Al.

Open Access Publications

No abstract provided.


End Points For Sickle Cell Disease Clinical Trials: Patient-Reported Outcomes, Pain, And The Brain, Ann T. Farrell, Allison A. King, Et Al. Jan 2019

End Points For Sickle Cell Disease Clinical Trials: Patient-Reported Outcomes, Pain, And The Brain, Ann T. Farrell, Allison A. King, Et Al.

Open Access Publications

No abstract provided.


Mechanisms Underlying Bone Loss Associated With Gut Inflammation, Ke Ke, Manoj Arra, Yousef Abu-Amer Jan 2019

Mechanisms Underlying Bone Loss Associated With Gut Inflammation, Ke Ke, Manoj Arra, Yousef Abu-Amer

Open Access Publications

Patients with gastrointestinal diseases frequently suffer from skeletal abnormality, characterized by reduced bone mineral density, increased fracture risk, and/or joint inflammation. This pathological process is characterized by altered immune cell activity and elevated inflammatory cytokines in the bone marrow microenvironment due to disrupted gut immune response. Gastrointestinal disease is recognized as an immune malfunction driven by multiple factors, including cytokines and signaling molecules. However, the mechanism by which intestinal inflammation magnified by gut-residing actors stimulates bone loss remains to be elucidated. In this article, we discuss the main risk factors potentially contributing to intestinal disease-associated bone loss, and summarize current …


A Review Of The Immunomodulating Components Of Maternal Breast Milk And Protection Against Necrotizing Enterocolitis, Lila S Nolan, Olivia B Parks, Misty Good Jan 2019

A Review Of The Immunomodulating Components Of Maternal Breast Milk And Protection Against Necrotizing Enterocolitis, Lila S Nolan, Olivia B Parks, Misty Good

Open Access Publications

Breast milk contains immunomodulating components that are beneficial to newborns during maturation of their immune system. Human breast milk composition is influenced by an infant's gestational and chronological age, lactation stage, and the mother and infant's health status. Major immunologic components in human milk, such as secretory immunoglobulin A (IgA) and growth factors, have a known role in regulating gut barrier integrity and microbial colonization, which therefore protect against the development of a life-threatening gastrointestinal illness affecting newborn infants called necrotizing enterocolitis (NEC). Breast milk is a known protective factor in the prevention of NEC when compared with feeding with …


The Zebrafish Xenograft Platform-A Novel Tool For Modeling Kshv-Associated Diseases, Eric S Pringle, Jaime Wertman, Nicole Melong, Andrew J Coombs, Andrew L Young, David O'Leary, Chansey Veinotte, Carolyn-Ann Robinson, Michael N Ha, Graham Dellaire, Todd E Druley, Craig Mccormick, Jason N Berman Jan 2019

The Zebrafish Xenograft Platform-A Novel Tool For Modeling Kshv-Associated Diseases, Eric S Pringle, Jaime Wertman, Nicole Melong, Andrew J Coombs, Andrew L Young, David O'Leary, Chansey Veinotte, Carolyn-Ann Robinson, Michael N Ha, Graham Dellaire, Todd E Druley, Craig Mccormick, Jason N Berman

Open Access Publications

Kaposi's sarcoma associated-herpesvirus (KSHV, also known as human herpesvirus-8) is a gammaherpesvirus that establishes life-long infection in human B lymphocytes. KSHV infection is typically asymptomatic, but immunosuppression can predispose KSHV-infected individuals to primary effusion lymphoma (PEL); a malignancy driven by aberrant proliferation of latently infected B lymphocytes, and supported by pro-inflammatory cytokines and angiogenic factors produced by cells that succumb to lytic viral replication. Here, we report the development of the first


Changes In Food Cravings And Eating Behavior After A Dietary Carbohydrate Restriction Intervention Trial, Katherene O-B Anguah, Majid M Syed-Abdul, Qiong Hu, Miriam Jacome-Sosa, Colette Heimowitz, Vicki Cox, Elizabeth J Parks Jan 2019

Changes In Food Cravings And Eating Behavior After A Dietary Carbohydrate Restriction Intervention Trial, Katherene O-B Anguah, Majid M Syed-Abdul, Qiong Hu, Miriam Jacome-Sosa, Colette Heimowitz, Vicki Cox, Elizabeth J Parks

Open Access Publications

Compared to low-fat diets, low-carbohydrate (CHO) diets cause weight loss (WL) over a faster time frame; however, it is unknown how changes in food cravings and eating behavior contribute to this more rapid WL in the early phases of dieting. We hypothesized that reductions in food cravings and improved eating behaviors would be evident even after a relatively short (4-week) duration of CHO-restriction, and that these changes would be associated with WL. Adult participants (


Gna11 Brain Somatic Pathogenic Variant In An Individual With Phacomatosis Pigmentovascularis, Joseph M. Sliepka, Yi-Shan Lee, Et Al. Jan 2019

Gna11 Brain Somatic Pathogenic Variant In An Individual With Phacomatosis Pigmentovascularis, Joseph M. Sliepka, Yi-Shan Lee, Et Al.

Open Access Publications

No abstract provided.


Selective Small Molecule Parg Inhibitor Causes Replication Fork Stalling And Cancer Cell Death, Jerry H. Houl, Roderick A. Stegeman, Tom Ellenberger, In-Kwon Kim, Et Al. Jan 2019

Selective Small Molecule Parg Inhibitor Causes Replication Fork Stalling And Cancer Cell Death, Jerry H. Houl, Roderick A. Stegeman, Tom Ellenberger, In-Kwon Kim, Et Al.

Open Access Publications

No abstract provided.