Digital Commons Network^™

Myeloid Acat1/Soat1 Ko Attenuates Pro-Inflammatory Responses In Macrophages And Protects Against Atherosclerosis In A Model Of Advanced Lesions, Elaina M. Melton, Haibo Li, Jalen Benson, Paul Sohn, Li-Hao Huang, Bao-Liang Song, Bo-Liang Li, Catherine C.Y. Chang, Ta-Yuan Chang

Open Access Publications

No abstract provided.

Phosphorylation Of The Hcn Channel Auxiliary Subunit Trip8b Is Altered In An Animal Model Of Temporal Lobe Epilepsy And Modulates Channel Function, Kendall M. Foote, Kyle A. Lyman, Ye Han, Ioannis E. Michailidis, Robert J. Heuermann, Danielle Mandikian, James S. Trimmer, Geoffrey T. Swanson, Dane M. Chetkovich

Open Access Publications

No abstract provided.

Safety And Efficacy Of Digital Single-Operator Pancreatoscopy For Obstructing Pancreatic Ductal Stones, Olaya I. Brewer Gutierrez, Daniel K. Mullady, Natalie Cosgrove, Et Al.

Open Access Publications

No abstract provided.

Implementation Of The Uterine Fibroids Option Grid Patient Decision Aids Across Five Organizational Settings: A Randomized Stepped-Wedge Study Protocol, Peter Scalia, Mary C. Politi, Tessa Madden, Et Al

Open Access Publications

No abstract provided.

Respiratory Viral Surveillance Of Healthcare Personnel And Patients At An Adult Long-Term Care Facility, Caroline A O'Neil, Lindsay Kim, Mila M Prill, H Keipp Talbot, Brett Whitaker, Senthilkumar K Sakthivel, Yange Zhang, Jing Zhang, Suxiang Tong, Nimalie Stone, Shikha Garg, Susan I Gerber, Hilary M Babcock

Open Access Publications

We conducted active surveillance of acute respiratory viral infections (ARIs) among residents and healthcare personnel (HCP) at a long-term care facility during the 2015-2016 respiratory illness season. ARIs were observed among both HCP and patients, highlighting the importance of including HCP in surveillance programs.

The Impact Of Surgeon Volume And Training Status On Implant Alignment In Total Knee Arthroplasty, Gregory S Kazarian, Charles M Lawrie, Toby N Barrack, Matthew J Donaldson, Gary M Miller, Fares S Haddad, Robert L Barrack

Open Access Publications

BACKGROUND: Implant malalignment may predispose patients to prosthetic failure following total knee arthroplasty (TKA). A more thorough understanding of the surgeon-specific factors that contribute to implant malalignment following TKA may uncover actionable strategies for improving implant survival. The purpose of this study was to determine the impact of surgeon volume and training status on malalignment.

METHODS: In this retrospective multicenter study, we performed a radiographic analysis of 1,570 primary TKAs performed at 4 private academic and state-funded centers in the U.S. and U.K. Surgeons were categorized as high-volume (≥50 TKAs/year) or low-volume (<50 TKAs/year), and as a trainee (fellow/resident under the supervision of an attending surgeon) or a non-trainee (attending surgeon). On the basis of these designations, 3 groups were defined: high-volume non-trainee, low-volume non-trainee, and trainee. The postoperative medial distal femoral angle (DFA), medial proximal tibial angle (PTA), and posterior tibial slope angle (PSA) were radiographically measured. Outlier measurements were defined as follows: DFA, outside of 5° ± 3° of valgus; PTA, >±3° deviation from the neutral axis; and …

Developmental Pathology Of Congenital Kidney And Urinary Tract Anomalies, Sanjay Jain, Feng Chen

Open Access Publications

No abstract provided.

Card And Rbpa Modify The Kinetics Of Initial Transcription And Slow Promoter Escape Of The Mycobacterium Tuberculosis Rna Polymerase, Drake Jensen, Ana R. Manzano, Christina L. Stallings, Eric A. Galburt

Open Access Publications

No abstract provided.

Dietary Pattern And Risk Of Multiple Myeloma In Two Large Prospective Us Cohort Studies, Dong Hoon Lee, Teresa T. Fung, Fred K. Tabung, Graham A. Colditz, Irene M. Ghobrial, Bernard A. Rosner, Edward L. Giovannucci, Brenda M. Birmann

Open Access Publications

No abstract provided.

Complementary Roles Of Pif1 Helicase And Single Stranded Dna Binding Proteins In Stimulating Dna Replication Through G-Quadruplexes, Melanie A. Sparks, Saurabh P. Singh, Peter M. Burgers, Roberto Galletto

Open Access Publications

No abstract provided.

Are The Intrinsically Disordered Linkers Involved In Ssb Binding To Accessory Proteins?, Min Kyung Shinn, Alexander G. Kozlov, Bihn Nguyen, Wlodek M. Bujalowski, Timothy M. Lohman

Open Access Publications

No abstract provided.

Association Between Rotator Cuff Muscle Size And Glenoid Deformity In Primary Glenohumeral Osteoarthritis, Alexander W Aleem, Peter N Chalmers, Daniel Bechtold, Adam Z Khan, Robert Z Tashjian, Jay D Keener

Open Access Publications

BACKGROUND: Although glenoid morphology has been associated with fatty infiltration of the rotator cuff in arthritic shoulders, the association of rotator cuff muscle area with specific patterns of glenoid wear has not been studied. The purpose of our study was to assess the associations of glenoid deformity in primary glenohumeral osteoarthritis and rotator cuff muscle area.

METHODS: A retrospective study of 370 computed tomographic (CT) scans of osteoarthritic shoulders was performed. Glenoid deformity according to the modified Walch classification was determined, and retroversion, inclination, and humeral-head subluxation were calculated using automated 3-dimensional software. Rotator cuff muscle area was measured on …

Pathogen-Negative Sepsis—An Opportunity For Antimicrobial Stewardship, Gabriel C. Lockhart, Jacob Hanin, Scott T. Micek, Marin H. Kollef

Open Access Publications

No abstract provided.

Comparison Of The Clinical Characteristics Of Hospital-Acquired And Non-Hospital-Acquired Acinetobacter Calcoaceticus-Baumannii Complex In A Large Midwest Us Health Care System, Juan J. Calix, Jason P. Burnham, Mario F. Feldman

Open Access Publications

No abstract provided.

Interdisciplinary Handover Between Obstetric Nursing And Neonatal Physician Teams: An Observational Study, Anshul Arora, Thomas Kannampallil, Joanna Abraham

Open Access Publications

Objective: We investigated the content and quality of communication of interservice interprofessional handover between obstetric nurses and neonatal physicians for high-risk deliveries.

Design: Observational study.

Setting: Labour and delivery unit at a tertiary care hospital.

Method: We audio-recorded handovers between obstetric and neonatal teams (n=50) and conducted clinician interviews (n=29). A handover content framework was developed and used to qualitatively code missing core and ancillary content and their potential for adverse events.

Results: 26 (52%) handovers missed one or more clinical content elements; a third of the handovers missed at least one core clinical content element. Increase in the number …

Understanding The Experience Of Psychopathology After Intimate Partner Violence: The Role Of Personality, Paulo A S Moreira, Márcia Pinto, C. Robert Cloninger, Daniela Rodrigues, Carlos Fernandes Da Silva

Open Access Publications

Objectives: To fully understand the dynamics of Intimate Partner Violence (IPV) it is necessary to understand the role of personality. The current understanding of which personality characteristics are associated with IPV victimization is, however, far from comprehensive. Given this gap in the literature, our objective was to examine the associations between the dimensions of the psychobiological model of personality and psychopathological symptoms in women who had experienced IPV.

Methods: Using a case-control design, a group of women who had experienced IPV and who were living in shelters (

Results: Victims of IPV showed significantly higher levels of Harm Avoidance and …

Npy2r Signaling Gates Spontaneous And Mechanical, But Not Thermal, Pain Transmission, Sihan Chen, Xian-Yu Liu, Yingfu Jiao, Zhou-Feng Chen, Weifeng Yu

Open Access Publications

No abstract provided.

Imaging Biomarkers Of Adiposity And Sarcopenia As Potential Predictors For Overall Survival Among Patients With Endometrial Cancer Treated With Bevacizumab, J. Gillen, K. A. Mills, J. Dvorak, B. Zheng, T. Thai, R. Salani, C. M. Cosgrove, B. Davidson, P. H. Thaker, K. N. Moore

Open Access Publications

No abstract provided.

Multiple Changes Underlie Allelic Divergence Of Cup2 Between Saccharomyces Species, Xueing C. Li, Justin C. Fay

Open Access Publications

No abstract provided.

Anchor Surgeon Views Of Patient Selection And Expectations For Periacetabular Osteotomy, Adam I. Edelstein, Karen Kaiser Tegal, Sara Shaunfield, Anchor Group, John C. Clohisy, Michael D. Stover

Open Access Publications

No abstract provided.

Complications Associated With Combined Surgical Hip Dislocation And Periacetabular Osteotomy For Complex Hip Deformities, Adam I. Edelstein, Stephen T. Duncan, Sean Akers, Gail Pashos, Perry L. Schoenecker, John C. Clohisy

Open Access Publications

No abstract provided.

Perspectives Of United States–Based Infectious Diseases Physicians On Outpatient Parenteral Antimicrobial Therapy Practice, Yasir Hamad, Michael A. Lane, Susan E. Beekmann, Philip M. Polgreen, Sara C. Keller

Open Access Publications

No abstract provided.

Neutralizing Antibodies Against Mayaro Virus Require Fc Effector Functions For Protective Activity, James T. Earnest, Katherine Basore, Vicky Roy, Adam L. Bailey, David Wang, Galit Alter, Daved H. Fremont, Michael S. Diamond

Open Access Publications

No abstract provided.

Rory Regulates The Nlrp3 Inflammasome, Cyrielle Billon, Meghan H. Murray, Amer Avdagic, Thomas P. Burris

Open Access Publications

No abstract provided.

Thiol Isomerase Erp57 Targets And Modulates The Lectin Pathway Of Complement Activation, Oskar Eriksson, Joyce Chiu, Philip J. Hogg, John P. Atkinson, M. Kathryn Liszewski, Robert Flaumenhaft, Bruce Furie

Open Access Publications

No abstract provided.

Photoreceptors In A Mouse Model Of Leigh Syndrome Are Capable Of Normal Light-Evoked Signaling, Sidney M. Gospe Iii, Amanda M. Travis, Alexander V. Kolesnikov, Mikael Klingeborn, Luyu Wang, Vladimir J. Kefalov, Vadim Y. Arshavsky

Open Access Publications

No abstract provided.

Nfat5 Up-Regulates Expression Of The Kidney-Specific Ubiquitin Ligase Gene Rnf183 Under Hypertonic Conditions In Inner-Medullary Collecting Duct Cells, Yujiro Maeoka, Yan Wu, Takumi Okamoto, Soshi Kanemoto, Xiao Peng Guo, Atsushi Saito, Rie Asada, Koji Matsuhisa, Takao Masaki, Kazunori Imaizumi, Masayuki Kaneko

Open Access Publications

No abstract provided.

Field-In-Field Breast Planning For A Jawless, Double-Stack Mlc Linac Using Flattening-Filter-Free Beams, Robert Morris, Eric Laugeman, Jessica Hilliard, Imran Zoberi, Ana Heerman, Geoffrey Hugo, Sasa Mutic, Bin Cai

Open Access Publications

BACKGROUND: This study intends to develop an efficient field-in-field (FiF) planning technique with the Eclipse treatment planning system (TPS) to determine the feasibility of using the Halcyon treatment delivery system for 3D treatment of breast cancer.

METHODS: Ten treatment plans were prepared on the Halcyon treatment planning system and compared to the same patients' clinically delivered TrueBeam plans which used flattened 6 MV and 10 MV beams. Patients selected for this study were treated via simple, tangential breast irradiation and did not receive radiotherapy of the supraclavicular or internal mammary lymph nodes. Planning target volumes (PTV) volumes ranged from 519 …

Identification And Characterization Of Nanh2 And Nanh3, Enzymes Responsible For Sialidase Activity In The Vaginal Bacterium Gardnerella Vaginalis, Lloyd S. Robinson, Jane Schwebke, Warren G. Lewis, Amanda L. Lewis

Open Access Publications

No abstract provided.

A Stable Tetramer Is Not The Only Oligomeric State That Mitochondrial Single-Stranded Dna Binding Proteins Can Adopt, Saurabh P. Singh, Vandna Kukshal, Roberto Galletto

Open Access Publications

No abstract provided.