Digital Commons Network^™

A Stable Tetramer Is Not The Only Oligomeric State That Mitochondrial Single-Stranded Dna Binding Proteins Can Adopt, Saurabh P. Singh, Vandna Kukshal, Roberto Galletto

Open Access Publications

No abstract provided.

Activation Of Tel1atm Kinase Requires Rad50 Atpase And Long Nucleosome-Free Dna But No Dna Ends, Sarem Hailemariam, Sandeep Kumar, Peter M. Burgers

Open Access Publications

No abstract provided.

Detection Of Tar Dna-Binding Protein 43 (Tdp-43) Oligomers As Initial Intermediate Species During Aggregate Formation, Rachel L. French, Zachary R. Grese, Himani Aligireddy, Dhruva D. Dhavale, Ashley N. Reeb, Niraja Kedia, Paul T. Kotzbauer, Jan Bieschke, Yuna M. Ayala

Open Access Publications

No abstract provided.

Disparities In Access To Musculoskeletal Care: Narrowing The Gap: Aoa Critical Issues Symposium, Dane H Salazar, Christopher J Dy, W Stephen Choate, Howard M Place

Open Access Publications

The current health-care system in the United States has numerous barriers to quality, accessible, and affordable musculoskeletal care for multiple subgroups of our population. These hurdles include complex cultural, educational, and socioeconomic factors. Tertiary referral centers provide a disproportionately large amount of the care for the uninsured and underinsured members of our society. These gaps in access to care for certain subgroups lead to inappropriate emergency room usage, lengthy hospitalizations, increased administrative load, lost productivity, and avoidable complications and/or deaths, which all represent a needless burden on our health-care system. Through advocacy, policy changes, workforce diversification, and practice changes, orthopaedic …

The Structure Of Acinetobacter-Secreted Protease Cpaa Complexed With Its Chaperone Cpab Reveals A Novel Mode Of A T2ss Chaperone–Substrate Interaction, Darya V. Urusova, Rachel L. Kinsella, Nichole D. Salinas, M. Florencia Haurat, Mario F. Feldman, Niraj H. Tolia

Open Access Publications

No abstract provided.

Synthesis And Characterization Of Diazirine Alkyne Probes For The Study Of Intracellular Cholesterol Trafficking, Mckenna Feltes, Samantha Moores, Sarah E. Gale, Kathiresan Krishnan, Laurel Mydock-Mcgrane, Douglas F. Covey, Daniel S. Ory, Jean E. Schaffer

Open Access Publications

No abstract provided.

Association Between The Hla-Drb1*03:01-Dqb1*02:01 Haplotype And Pf4/Heparin Antibodies, Ray Zhang, Brian F. Duffy, Vinzenz Lange, Charles S. Eby, Chang Liu

Open Access Publications

No abstract provided.

The Complex Genetics And Biology Of Human Temperament: A Review Of Traditional Concepts In Relation To New Molecular Findings, C. Robert Cloninger, Kevin M. Cloninger, Igor Zwir, Lisa Keltikangas-Järvinen

Open Access Publications

No abstract provided.

Operative Vaginal Delivery Is A Safe Option In Women Undergoing A Trial Of Labor After Cesarean, Erin Krizman, Patricia Grzebielski, Kathleen M Antony, Emmanuel Sampene, Matthew Shanahan, J Igor Iruretagoyena, Justin Bohrer

Open Access Publications

No abstract provided.

Oxytocin And Oxytocinase In The Obese And Nonobese Parturients During Induction And Augmentation Of Labor, Annemaria De Tina, Jeremy Juang, Thomas F Mcelrath, Jack D Baty, Arvind Palanisamy

Open Access Publications

No abstract provided.

Hepatic Monoacylglycerol Acyltransferase 1 Is Induced By Prolonged Food Deprivation To Modulate The Hepatic Fasting Response, Andrew J. Lutkewitte, Kyle S. Mccommis, George G. Schweitzer, Kari T. Chambers, Mark J. Graham, Lingjue Wang, Gary J. Patti, Angela M. Hall, Brian N. Finck

Open Access Publications

No abstract provided.

Synthesis Of Oxidized Phospholipids By Sn-1 Acyltransferase Using 2–15-Hete Lysophospholipids, Gao-Yuan Liu, Sung Ho Moon, Christopher M. Jenkins, Harold F. Sims, Shaoping Guan, Richard W. Gross

Open Access Publications

No abstract provided.

Insulin-Independent Reversal Of Type-1 Diabetes Following Transplantation Of Adult Brown Adipose Tissue Supplemented With Igf-1, Subhadra C. Gunawardana, David W. Piston

Open Access Publications

No abstract provided.

Visual Field Loss In Patients With Diabetes In The Absence Of Clinically-Detectable Vascular Retinopathy In A Nationally Representative Survey, Yicheng K. Bao, Yan Yan, Mae Gordon, Janet B. Mcgill, Michael Kass, Rithwick Rajagopal

Open Access Publications

No abstract provided.

Graft Immaturity And Safety Concerns In Transplanted Human Kidney Organoids, Sun Ah Nam, Kohei Uchimura, Benjamin D. Humphreys, Et Al.

Open Access Publications

No abstract provided.

Dissemination And Stakeholder Engagement Practices Among Dissemination & Implementation Scientists: Results From An Online Survey, Christopher E. Knoepke, M. Pilar Ingle, Daniel D. Matlock, Ross C. Brownson, Russell E. Glasgow

Open Access Publications

No abstract provided.

Urinary Tract Infections After Combat-Related Genitourinary Trauma, Stephen Y. Liang, Brendan Jackson, Janis Kuhn, Faraz Shaikh, Dana M. Blyth, Timothy J. Whitman, Joseph L. Petfield, M. Leigh Carson, David R. Tribble, Jay R. Mcdonald, Infectious Disease Clinical Research Program Trauma Infectious Disease Outcomes Study Group

Open Access Publications

No abstract provided.

Stunting Is Preceded By Intestinal Mucosal Damage And Microbiome Changes And Is Associated With Systemic Inflammation In A Cohort Of Peruvian Infants, Mara Zambruni, Theresa J Ochoa, Anoma Somasunderam, Miguel M Cabada, Maria L Morales, Makedonka Mitreva, Bruce A Rosa, Gonzalo J Acosta, Natalia I Vigo, Maribel Riveros, Sara Arango, David Durand, Maitreyee N Berends, Peter Melby, Netanya S Utay

Open Access Publications

Stunting, defined as height-for-age

Heterogeneity Diffusion Imaging Of Gliomas: Initial Experience And Validation, Qing Wang, Gloria J. Guzmán Pérez-Carrillo, Maria Rosana Ponisio, Pamela Lamontagne, Sonika Dahiya, Daniel S. Marcus, Mikhail Milchenko, Joshua Shimony, Jingxia Liu, Gengsheng Chen, Amber Salter, Parinaz Massoumzadeh, Michelle M. Miller-Thomas, Keith M. Rich, Jonathan Mcconathy, Tammie L. S. Benzinger, Yong Wang

Open Access Publications

OBJECTIVES: Primary brain tumors are composed of tumor cells, neural/glial tissues, edema, and vasculature tissue. Conventional MRI has a limited ability to evaluate heterogeneous tumor pathologies. We developed a novel diffusion MRI-based method-Heterogeneity Diffusion Imaging (HDI)-to simultaneously detect and characterize multiple tumor pathologies and capillary blood perfusion using a single diffusion MRI scan.

METHODS: Seven adult patients with primary brain tumors underwent standard-of-care MRI protocols and HDI protocol before planned surgical resection and/or stereotactic biopsy. Twelve tumor sampling sites were identified using a neuronavigational system and recorded for imaging data quantification. Metrics from both protocols were compared between World Health …

Glutathione Synthesis Contributes To Virulence Of Streptococcus Agalactiae In A Murine Model Of Sepsis, Elizabeth A Walker, Gary C Port, Michael G Caparon, Blythe E Janowiak

Open Access Publications

No abstract provided.

Two-Photon Microperimetry: Sensitivity Of Human Photoreceptors To Infrared Light, Daniel Ruminski, Grazyna Palczewska, Maciej Nowakowski, Agnieszka Zielińska, Vladimir J Kefalov, Katarzyna Komar, Krzysztof Palczewski, Maciej Wojtkowski

Open Access Publications

Microperimetry is a subjective ophthalmologic test used to assess retinal function at various specific and focal locations of the visual field. Historically, visible light has been described as ranging from 400 to 720 nm. However, we previously demonstrated that infra-red light can initiate visual transduction in rod photoreceptors by a mechanism of two-photon absorption by visual pigments. Here we introduce a newly designed and constructed two-photon microperimeter. We provide for the first time evidence of the presence of a nonlinear process occurring in the human retina based on psychophysical tests using newly developed instrumentation. Since infra-red light penetrates the aged …

Advanced Glycation End Products Are Elevated In Estrogen Receptor-Positive Breast Cancer Patients, Alter Response To Therapy, And Can Be Targeted By Lifestyle Intervention, Katherine R. Walter, Lindsay L. Peterson, Et Al

Open Access Publications

No abstract provided.

The Children's Respiratory And Environmental Workgroup (Crew) Birth Cohort Consortium: Design, Methods, And Study Population, James E. Gern, Leonard B. Bacharier, Et Al

Open Access Publications

No abstract provided.

Building A Culture Of Health And Well-Being At Merck, Cathryn E. Gunther, Virginia Peddicord, Joseph Kozlowski, Yi Li, Danielle Menture, Raymond Fabius, Sharon Glave Frazee, Peter J. Nigro

Open Access Publications

No abstract provided.

A Fatal Case Of Disseminated Microsporidiosis Due To Anncaliia Algerae In A Renal And Pancreas Allograft Recipient, Neil W. Anderson, Atis Muehlenbachs, Sana Arif, Jackrapong Bruminhent, Paul J. Deziel, Raymund R. Razonable, Mark P. Wilhelm, Maureen G. Metcalfe, Yvonne Qvarnstrom, Bobbi S. Pritt

Open Access Publications

No abstract provided.

Prevalence And Impact Of Hepatitis E Virus Infection Among Persons With Chronic Hepatitis B Living In The Us And Canada, David R. Mcgivern, Hsing-Hua S. Lin, Junyao Wang, Tiffany Benzine, Henry L.A Janssen, Mandana Khalili, Mauricio Lisker-Melman, Robert J. Fontana, Steven H. Belle, Michael W. Fried

Open Access Publications

No abstract provided.

Seasonal Changes In The Prevalence Of Antibiotic-Susceptible Acinetobacter Calcoaceticus-Baumannii Complex Isolates Result In Increased Multidrug Resistance Rates During Winter Months, Jason P. Burnham, Mario F. Feldman, Juan J. Calix

Open Access Publications

No abstract provided.

The Role Of Fecal Microbiota Transplantation In Reducing Intestinal Colonization With Antibiotic-Resistant Organisms: The Current Landscape And Future Directions, Michael H. Woodworth, Mary K. Hayden, Vincent B. Young, Jennie H. Kwon

Open Access Publications

No abstract provided.

Clinical Impact Of Revised Cefepime Breakpoint In Patients With Enterobacteriaceae Bacteremia, Kap Sum Foong, Abigail L. Carlson, Munigala Satish, Carey-Ann D. Burnham, David K. Warren

Open Access Publications

No abstract provided.

Alcohol Binge-Induced Cardiovascular Dysfunction Involves Endocannabinoid–Cb1-R Signaling, Janos Paloczi, Csaba Matyas, Resat Cinar, Zoltan V. Varga, György Hasko, Thomas H. Schindler, George Kunos, Pal Pacher

Open Access Publications

No abstract provided.