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2019

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Self-Transcendence In Mountaineering And Base Jumping, Erik Monasterio, C. Robert Cloninger Jan 2019

Self-Transcendence In Mountaineering And Base Jumping, Erik Monasterio, C. Robert Cloninger

Open Access Publications

No abstract provided.


Chronic Pain And Chronic Opioid Use After Intensive Care Discharge – Is It Time To Change Practice?, Dusica M. Stemenkovic, Helen Laycock, Menelaos Karanikolas, Nebojsa Gojko Ladjevic, Vojislava Neskovic, Carsten Bantel Jan 2019

Chronic Pain And Chronic Opioid Use After Intensive Care Discharge – Is It Time To Change Practice?, Dusica M. Stemenkovic, Helen Laycock, Menelaos Karanikolas, Nebojsa Gojko Ladjevic, Vojislava Neskovic, Carsten Bantel

Open Access Publications

No abstract provided.


Nicotine Oxidation By Genetic Variants Of Cyp2b6 And In Human Brain Microsomes, Adam Joseph Bloom, Pan-Fen Wang, Evan D. Kharasch Jan 2019

Nicotine Oxidation By Genetic Variants Of Cyp2b6 And In Human Brain Microsomes, Adam Joseph Bloom, Pan-Fen Wang, Evan D. Kharasch

Open Access Publications

No abstract provided.


Novel Chitohexaose Analog Protects Young And Aged Mice From Clp Induced Polymicrobial Sepsis, Pragnya Das, Santosh K. Panda, Beamon Agarwal, Sumita Behera, Syed M. Ali, Mark E. Pulse, Joseph S. Solomkin, Steven M. Opal, Vineet Bhandari, Suchismita Acharya Jan 2019

Novel Chitohexaose Analog Protects Young And Aged Mice From Clp Induced Polymicrobial Sepsis, Pragnya Das, Santosh K. Panda, Beamon Agarwal, Sumita Behera, Syed M. Ali, Mark E. Pulse, Joseph S. Solomkin, Steven M. Opal, Vineet Bhandari, Suchismita Acharya

Open Access Publications

No abstract provided.


Role Of Arginase 2 In Systemic Metabolic Activity And Adipose Tissue Fatty Acid Metabolism In Diet-Induced Obese Mice, Reem T. Atawia, Haroldo A. Toque, Mohamed M. Meghil, Tyler W. Benson, Nicole K.H Yiew, Christopher W. Cutler, Neal L. Weintraub, Ruth B. Caldwell, Robert W. Caldwell Jan 2019

Role Of Arginase 2 In Systemic Metabolic Activity And Adipose Tissue Fatty Acid Metabolism In Diet-Induced Obese Mice, Reem T. Atawia, Haroldo A. Toque, Mohamed M. Meghil, Tyler W. Benson, Nicole K.H Yiew, Christopher W. Cutler, Neal L. Weintraub, Ruth B. Caldwell, Robert W. Caldwell

Open Access Publications

No abstract provided.


X-Ray Structures Of The High-Affinity Copper Transporter Ctr1, Feifei Ren, Brandon L. Logeman, Xiaohui Zhang, Yongjian Liu, Dennis J. Thiele, Peng Yuan Jan 2019

X-Ray Structures Of The High-Affinity Copper Transporter Ctr1, Feifei Ren, Brandon L. Logeman, Xiaohui Zhang, Yongjian Liu, Dennis J. Thiele, Peng Yuan

Open Access Publications

No abstract provided.


Two-Year Evaluation Of Mandatory Bundled Payments For Joint Replacement, Michael L. Barnett, Andrew Wilcock, J. Michael Mcwilliams, Arnold M. Epstein, Karen E. Joynt Maddox, E. John Orav, David C. Grabowski, Ateev Mehrotra Jan 2019

Two-Year Evaluation Of Mandatory Bundled Payments For Joint Replacement, Michael L. Barnett, Andrew Wilcock, J. Michael Mcwilliams, Arnold M. Epstein, Karen E. Joynt Maddox, E. John Orav, David C. Grabowski, Ateev Mehrotra

Open Access Publications

No abstract provided.


Comparison Of Two Models Of Family-Based Treatment For Childhood Obesity: A Pilot Study, Kristie Bergmann, Zoe Mestre, David Strong, Dawn M. Eichen, Kyung Rhee, Scott Crow, Denise Wilfley, Kerri N. Boutelle Jan 2019

Comparison Of Two Models Of Family-Based Treatment For Childhood Obesity: A Pilot Study, Kristie Bergmann, Zoe Mestre, David Strong, Dawn M. Eichen, Kyung Rhee, Scott Crow, Denise Wilfley, Kerri N. Boutelle

Open Access Publications

No abstract provided.


The Macaque Cerebellar Flocculus Outputs A Forward Model Of Eye Movement, Gyutae Kim, Jean Laurens, Tatyana A. Yakusheva, Pablo M. Blazquez Jan 2019

The Macaque Cerebellar Flocculus Outputs A Forward Model Of Eye Movement, Gyutae Kim, Jean Laurens, Tatyana A. Yakusheva, Pablo M. Blazquez

Open Access Publications

No abstract provided.


Steady-State Activation Of The High-Affinity Isoform Of The Α4Β2Δ Gabaa Receptor, Spencer R. Pierce, Thomas C. Senneff, Allison L. Germann, Gustav Akk Jan 2019

Steady-State Activation Of The High-Affinity Isoform Of The Α4Β2Δ Gabaa Receptor, Spencer R. Pierce, Thomas C. Senneff, Allison L. Germann, Gustav Akk

Open Access Publications

No abstract provided.


Myeloid Acat1/Soat1 Ko Attenuates Pro-Inflammatory Responses In Macrophages And Protects Against Atherosclerosis In A Model Of Advanced Lesions, Elaina M. Melton, Haibo Li, Jalen Benson, Paul Sohn, Li-Hao Huang, Bao-Liang Song, Bo-Liang Li, Catherine C.Y. Chang, Ta-Yuan Chang Jan 2019

Myeloid Acat1/Soat1 Ko Attenuates Pro-Inflammatory Responses In Macrophages And Protects Against Atherosclerosis In A Model Of Advanced Lesions, Elaina M. Melton, Haibo Li, Jalen Benson, Paul Sohn, Li-Hao Huang, Bao-Liang Song, Bo-Liang Li, Catherine C.Y. Chang, Ta-Yuan Chang

Open Access Publications

No abstract provided.


Safety And Efficacy Of Digital Single-Operator Pancreatoscopy For Obstructing Pancreatic Ductal Stones, Olaya I. Brewer Gutierrez, Daniel K. Mullady, Natalie Cosgrove, Et Al. Jan 2019

Safety And Efficacy Of Digital Single-Operator Pancreatoscopy For Obstructing Pancreatic Ductal Stones, Olaya I. Brewer Gutierrez, Daniel K. Mullady, Natalie Cosgrove, Et Al.

Open Access Publications

No abstract provided.


Respiratory Viral Surveillance Of Healthcare Personnel And Patients At An Adult Long-Term Care Facility, Caroline A O'Neil, Lindsay Kim, Mila M Prill, H Keipp Talbot, Brett Whitaker, Senthilkumar K Sakthivel, Yange Zhang, Jing Zhang, Suxiang Tong, Nimalie Stone, Shikha Garg, Susan I Gerber, Hilary M Babcock Jan 2019

Respiratory Viral Surveillance Of Healthcare Personnel And Patients At An Adult Long-Term Care Facility, Caroline A O'Neil, Lindsay Kim, Mila M Prill, H Keipp Talbot, Brett Whitaker, Senthilkumar K Sakthivel, Yange Zhang, Jing Zhang, Suxiang Tong, Nimalie Stone, Shikha Garg, Susan I Gerber, Hilary M Babcock

Open Access Publications

We conducted active surveillance of acute respiratory viral infections (ARIs) among residents and healthcare personnel (HCP) at a long-term care facility during the 2015-2016 respiratory illness season. ARIs were observed among both HCP and patients, highlighting the importance of including HCP in surveillance programs.


Association Between Rotator Cuff Muscle Size And Glenoid Deformity In Primary Glenohumeral Osteoarthritis, Alexander W Aleem, Peter N Chalmers, Daniel Bechtold, Adam Z Khan, Robert Z Tashjian, Jay D Keener Jan 2019

Association Between Rotator Cuff Muscle Size And Glenoid Deformity In Primary Glenohumeral Osteoarthritis, Alexander W Aleem, Peter N Chalmers, Daniel Bechtold, Adam Z Khan, Robert Z Tashjian, Jay D Keener

Open Access Publications

BACKGROUND: Although glenoid morphology has been associated with fatty infiltration of the rotator cuff in arthritic shoulders, the association of rotator cuff muscle area with specific patterns of glenoid wear has not been studied. The purpose of our study was to assess the associations of glenoid deformity in primary glenohumeral osteoarthritis and rotator cuff muscle area.

METHODS: A retrospective study of 370 computed tomographic (CT) scans of osteoarthritic shoulders was performed. Glenoid deformity according to the modified Walch classification was determined, and retroversion, inclination, and humeral-head subluxation were calculated using automated 3-dimensional software. Rotator cuff muscle area was measured on …


Pathogen-Negative Sepsis—An Opportunity For Antimicrobial Stewardship, Gabriel C. Lockhart, Jacob Hanin, Scott T. Micek, Marin H. Kollef Jan 2019

Pathogen-Negative Sepsis—An Opportunity For Antimicrobial Stewardship, Gabriel C. Lockhart, Jacob Hanin, Scott T. Micek, Marin H. Kollef

Open Access Publications

No abstract provided.


Understanding The Experience Of Psychopathology After Intimate Partner Violence: The Role Of Personality, Paulo A S Moreira, Márcia Pinto, C. Robert Cloninger, Daniela Rodrigues, Carlos Fernandes Da Silva Jan 2019

Understanding The Experience Of Psychopathology After Intimate Partner Violence: The Role Of Personality, Paulo A S Moreira, Márcia Pinto, C. Robert Cloninger, Daniela Rodrigues, Carlos Fernandes Da Silva

Open Access Publications

Objectives: To fully understand the dynamics of Intimate Partner Violence (IPV) it is necessary to understand the role of personality. The current understanding of which personality characteristics are associated with IPV victimization is, however, far from comprehensive. Given this gap in the literature, our objective was to examine the associations between the dimensions of the psychobiological model of personality and psychopathological symptoms in women who had experienced IPV.

Methods: Using a case-control design, a group of women who had experienced IPV and who were living in shelters (

Results: Victims of IPV showed significantly higher levels of Harm Avoidance and …


Imaging Biomarkers Of Adiposity And Sarcopenia As Potential Predictors For Overall Survival Among Patients With Endometrial Cancer Treated With Bevacizumab, J. Gillen, K. A. Mills, J. Dvorak, B. Zheng, T. Thai, R. Salani, C. M. Cosgrove, B. Davidson, P. H. Thaker, K. N. Moore Jan 2019

Imaging Biomarkers Of Adiposity And Sarcopenia As Potential Predictors For Overall Survival Among Patients With Endometrial Cancer Treated With Bevacizumab, J. Gillen, K. A. Mills, J. Dvorak, B. Zheng, T. Thai, R. Salani, C. M. Cosgrove, B. Davidson, P. H. Thaker, K. N. Moore

Open Access Publications

No abstract provided.


Nfat5 Up-Regulates Expression Of The Kidney-Specific Ubiquitin Ligase Gene Rnf183 Under Hypertonic Conditions In Inner-Medullary Collecting Duct Cells, Yujiro Maeoka, Yan Wu, Takumi Okamoto, Soshi Kanemoto, Xiao Peng Guo, Atsushi Saito, Rie Asada, Koji Matsuhisa, Takao Masaki, Kazunori Imaizumi, Masayuki Kaneko Jan 2019

Nfat5 Up-Regulates Expression Of The Kidney-Specific Ubiquitin Ligase Gene Rnf183 Under Hypertonic Conditions In Inner-Medullary Collecting Duct Cells, Yujiro Maeoka, Yan Wu, Takumi Okamoto, Soshi Kanemoto, Xiao Peng Guo, Atsushi Saito, Rie Asada, Koji Matsuhisa, Takao Masaki, Kazunori Imaizumi, Masayuki Kaneko

Open Access Publications

No abstract provided.


Field-In-Field Breast Planning For A Jawless, Double-Stack Mlc Linac Using Flattening-Filter-Free Beams, Robert Morris, Eric Laugeman, Jessica Hilliard, Imran Zoberi, Ana Heerman, Geoffrey Hugo, Sasa Mutic, Bin Cai Jan 2019

Field-In-Field Breast Planning For A Jawless, Double-Stack Mlc Linac Using Flattening-Filter-Free Beams, Robert Morris, Eric Laugeman, Jessica Hilliard, Imran Zoberi, Ana Heerman, Geoffrey Hugo, Sasa Mutic, Bin Cai

Open Access Publications

BACKGROUND: This study intends to develop an efficient field-in-field (FiF) planning technique with the Eclipse treatment planning system (TPS) to determine the feasibility of using the Halcyon treatment delivery system for 3D treatment of breast cancer.

METHODS: Ten treatment plans were prepared on the Halcyon treatment planning system and compared to the same patients' clinically delivered TrueBeam plans which used flattened 6 MV and 10 MV beams. Patients selected for this study were treated via simple, tangential breast irradiation and did not receive radiotherapy of the supraclavicular or internal mammary lymph nodes. Planning target volumes (PTV) volumes ranged from 519 …


Operative Vaginal Delivery Is A Safe Option In Women Undergoing A Trial Of Labor After Cesarean, Erin Krizman, Patricia Grzebielski, Kathleen M Antony, Emmanuel Sampene, Matthew Shanahan, J Igor Iruretagoyena, Justin Bohrer Jan 2019

Operative Vaginal Delivery Is A Safe Option In Women Undergoing A Trial Of Labor After Cesarean, Erin Krizman, Patricia Grzebielski, Kathleen M Antony, Emmanuel Sampene, Matthew Shanahan, J Igor Iruretagoyena, Justin Bohrer

Open Access Publications

No abstract provided.


Glutathione Synthesis Contributes To Virulence Of Streptococcus Agalactiae In A Murine Model Of Sepsis, Elizabeth A Walker, Gary C Port, Michael G Caparon, Blythe E Janowiak Jan 2019

Glutathione Synthesis Contributes To Virulence Of Streptococcus Agalactiae In A Murine Model Of Sepsis, Elizabeth A Walker, Gary C Port, Michael G Caparon, Blythe E Janowiak

Open Access Publications

No abstract provided.


Prevalence And Impact Of Hepatitis E Virus Infection Among Persons With Chronic Hepatitis B Living In The Us And Canada, David R. Mcgivern, Hsing-Hua S. Lin, Junyao Wang, Tiffany Benzine, Henry L.A Janssen, Mandana Khalili, Mauricio Lisker-Melman, Robert J. Fontana, Steven H. Belle, Michael W. Fried Jan 2019

Prevalence And Impact Of Hepatitis E Virus Infection Among Persons With Chronic Hepatitis B Living In The Us And Canada, David R. Mcgivern, Hsing-Hua S. Lin, Junyao Wang, Tiffany Benzine, Henry L.A Janssen, Mandana Khalili, Mauricio Lisker-Melman, Robert J. Fontana, Steven H. Belle, Michael W. Fried

Open Access Publications

No abstract provided.


U.S. Adolescent And Adult Women's Experiences Accessing And Using Toilets In Schools, Workplaces, And Public Spaces: A Multi-Site Focus Group Study To Inform Future Research In Bladder Health, Deepa R Camenga, Sonya S Brady, Cecilia T Hardacker, Beverly R Williams, Jeni Hebert-Beirne, Aimee S James, Kathryn Burgio, Jesse Nodora, Jean F Wyman, Amanda Berry, Lisa K Low, Prevention Of Lower Urinary Tract Symptoms (Plus) Research Consortium Jan 2019

U.S. Adolescent And Adult Women's Experiences Accessing And Using Toilets In Schools, Workplaces, And Public Spaces: A Multi-Site Focus Group Study To Inform Future Research In Bladder Health, Deepa R Camenga, Sonya S Brady, Cecilia T Hardacker, Beverly R Williams, Jeni Hebert-Beirne, Aimee S James, Kathryn Burgio, Jesse Nodora, Jean F Wyman, Amanda Berry, Lisa K Low, Prevention Of Lower Urinary Tract Symptoms (Plus) Research Consortium

Open Access Publications

The World Health Organization recognizes access to clean and safe toilets as crucial for public health. This study explored U.S. adolescent and adult cisgender women's lived experiences accessing toilets in schools, workplaces, and public spaces. As part of the Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium, we conducted 44 focus groups with female participants (n = 360; ages 11-93). Focus groups were stratified by age (11-14, 15-17, 18-25, 26-44, 45-64, 65+) and conducted across 7 geographically diverse U.S. sites from July 2017-April 2018. Using a transdisciplinary approach, we conducted conventional qualitative coding informed by our PLUS conceptual framework …


Aebp1 Down Regulation Induced Cell Death Pathway Depends On Pten Status Of Glioma Cells, Swati Sinha, Arun Renganathan, Prathima B. Nagendra, Vasudeva Bhat, Brian Steve Mathew, Manchanahalli R. Satyanarayana Rao Jan 2019

Aebp1 Down Regulation Induced Cell Death Pathway Depends On Pten Status Of Glioma Cells, Swati Sinha, Arun Renganathan, Prathima B. Nagendra, Vasudeva Bhat, Brian Steve Mathew, Manchanahalli R. Satyanarayana Rao

Open Access Publications

No abstract provided.


Five-Year Outcomes Of The S1106 Study Of R-Hyper-Cvad Vs R-Bendamustine In Transplant-Eligible Patients With Mantle Cell Lymphoma, Manali Kamdar, Hongli Li, Robert W. Chen, Lisa M. Rimsza, Michael L. Leblanc, Timothy S. Fenske, Thomas C. Shea, Paul M. Barr, Tycel J. Phillips, John P. Leonard, Brad S. Kahl, Jonathan W. Friedberg, Sonali M. Smith Jan 2019

Five-Year Outcomes Of The S1106 Study Of R-Hyper-Cvad Vs R-Bendamustine In Transplant-Eligible Patients With Mantle Cell Lymphoma, Manali Kamdar, Hongli Li, Robert W. Chen, Lisa M. Rimsza, Michael L. Leblanc, Timothy S. Fenske, Thomas C. Shea, Paul M. Barr, Tycel J. Phillips, John P. Leonard, Brad S. Kahl, Jonathan W. Friedberg, Sonali M. Smith

Open Access Publications

No abstract provided.


Hyper-Activation Of Stat3 Sustains Progression Of Non-Papillary Basal-Type Bladder Cancer Via Fosl1 Regulome, William Vermi, Et Al Jan 2019

Hyper-Activation Of Stat3 Sustains Progression Of Non-Papillary Basal-Type Bladder Cancer Via Fosl1 Regulome, William Vermi, Et Al

Open Access Publications

No abstract provided.


Are Patients With Perforated Peptic Ulcers Who Are Negative For Helicobacter Pylori At A Greater Risk?, Rohit K. Rasane, Christopher B. Horn, Adrian A. Coleoglou Centeno, Nicholas B. Fiore, Marlon Torres Barboza, Qiao Zhang, Kelly M. Bochicchio, Laurie J. Punch, Grant V. Bochicchio, Obeid N. Ilahi Jan 2019

Are Patients With Perforated Peptic Ulcers Who Are Negative For Helicobacter Pylori At A Greater Risk?, Rohit K. Rasane, Christopher B. Horn, Adrian A. Coleoglou Centeno, Nicholas B. Fiore, Marlon Torres Barboza, Qiao Zhang, Kelly M. Bochicchio, Laurie J. Punch, Grant V. Bochicchio, Obeid N. Ilahi

Open Access Publications

No abstract provided.


Targeting Innate Immunity For Tuberculosis Vaccination, Shabaana A. Khader, Maziar Divangahi, Willem Hanekom, Philip C. Hill, Markus Maeurer, Karen W. Makar, Katrin D. Mayer-Barber, Musa M. Mhlanga, Elisa Nemes, Larry S. Schlesinger, Reinout Van Crevel, Ramakrishna Vankalayapati, Ramnik J. Xavier, Mihai G. Netea, On Behalf Of The Bill And Melinda Gates Foundation Collaboration For Tb Vaccine Discovery Innate Immunity Working Group Jan 2019

Targeting Innate Immunity For Tuberculosis Vaccination, Shabaana A. Khader, Maziar Divangahi, Willem Hanekom, Philip C. Hill, Markus Maeurer, Karen W. Makar, Katrin D. Mayer-Barber, Musa M. Mhlanga, Elisa Nemes, Larry S. Schlesinger, Reinout Van Crevel, Ramakrishna Vankalayapati, Ramnik J. Xavier, Mihai G. Netea, On Behalf Of The Bill And Melinda Gates Foundation Collaboration For Tb Vaccine Discovery Innate Immunity Working Group

Open Access Publications

No abstract provided.


A Window On The Lung: Molecular Imaging As A Tool To Dissect Pathophysiologic Mechanisms Of Acute Lung Disease, Guido Musch Jan 2019

A Window On The Lung: Molecular Imaging As A Tool To Dissect Pathophysiologic Mechanisms Of Acute Lung Disease, Guido Musch

Open Access Publications

No abstract provided.


Trial Of Sage-217 In Patients With Major Depressive Disorder, Handan Gunduz-Bruce, Christopher Silber, Inder Kaul, Anthony J. Rothschild, Robert Riesenberg, Abdul J. Sankoh, Haihong Li, Robert Lasser, Charles F. Zorumski, David R. Rubinow, Steven M. Paul, Jeffrey Jonas, James J. Doherty, Stephen J. Kanes Jan 2019

Trial Of Sage-217 In Patients With Major Depressive Disorder, Handan Gunduz-Bruce, Christopher Silber, Inder Kaul, Anthony J. Rothschild, Robert Riesenberg, Abdul J. Sankoh, Haihong Li, Robert Lasser, Charles F. Zorumski, David R. Rubinow, Steven M. Paul, Jeffrey Jonas, James J. Doherty, Stephen J. Kanes

Open Access Publications

No abstract provided.