Digital Commons Network^™

Buckley 2.0: How Would The Buckley Court Decide Buckley Today?, Miriam Galston

GW Law Faculty Publications & Other Works

If you read Supreme Court campaign finance cases, you will be struck by the disconnect between the lofty rhetoric used to justify the constitutional protections afforded political speech and the impoverished sound bites and hyperbolic attack ads that dominate contemporary electoral communications. The origin of this disconnect is in large part two phenomena. First, in the last decade the Court has failed to take the factual record seriously and, as a result, makes generalizations that are belied by contemporary campaign practices. Relatedly, the Court has adopted doctrines that co-exist in uneasy relationships with campaign finance doctrines of longstanding. As a …

Delegation, Time, And Congressional Capacity: A Response To Adler And Walker, Richard J. Pierce Jr

GW Law Faculty Publications & Other Works

This is a response to an article by Jonathan Adler and Chris Walker. In Delegation and Time, Adler and Walker introduce an important new way of thinking about broad congressional delegations of power. After reviewing the traditional arguments against broad congressional delegations of power they note that broad delegations increasingly raise a serious temporal problem.

In their words, “broad congressional delegations of authority at one time period become a source of authority for agencies to take action at a later time that was wholly unanticipated by the enacting Congress or could no longer receive legislative support.” They also note that …

Effect Of Mental And Physical Practice On Clinical Skill Learning In Kinesiology, Melanie E. Perreault, Christopher Brown, Robert J. Doan, David R. Dolbow

Internet Journal of Allied Health Sciences and Practice

Purpose: The amount of information required for an allied health professional has increased dramatically. In-class practice time and large amounts of practice materials may be difficult for instructors to acquire. Mental practice is a method of practice that does not involve physical movement or materials. This study investigated the effect of mental practice, physical practice, and a combination of mental and physical practice on kinesiology students learning three manual muscle tests.

Method: Fifty-six students aged 18 to 26 years (M = 20.09, SD + 1.58), pursuing a degree in kinesiology with an emphasis in either athletic training or kinesiotherapy …

The Experience And Perception Of Physiotherapists In Nigeria Re: Fall Prevention In Recurrent-Faller Older Adults, Perpetua Chinenye Obi, Henrietha Chibuzor Nwankwo, Diaemeta Emofe, Isreal Adandom, Michael E. Kalu

Internet Journal of Allied Health Sciences and Practice

Background: Effective fall prevention practices are essential for reducing falls among older adults. Rehabilitation professionals like physiotherapists are essential members of the fall prevention team, yet little is known about the experiences of physiotherapists practicing fall prevention in developing nations. Objective: To explore the experiences of physiotherapists in Nigeria who practice fall prevention among older adults. Method: We adopted a phenomenological approach to the traditional qualitative design in this study. We purposefully selected and conducted face-to-face interview with twelve physiotherapists who have treated at least one older adult who reported falling two or three times within last six months. Data …

Graphene Nanoflake Uptake Mediated By Scavenger Receptors, Fatima Alnasser, Valentina Castagnola, Luca Boselli, Margarita Esquivel-Gaon, Esen Efeoglu, Jennifer Mcintyre, Hugh Byrne, Kenneth A. Dawson

Articles

The biological interactions of graphene have been extensively investigated over the last 10 years. However, very little is known about graphene interactions with the cell surface and how the graphene internalization process is driven and mediated by specific recognition sites at the interface with the cell. In this work, we propose a methodology to investigate direct molecular correlations between the biomolecular corona of graphene and specific cell receptors, showing that key protein recognition motifs, presented on the nanomaterial surface, can engage selectively with specific cell receptors. We consider the case of apolipoprotein A-I, found to be very abundant in the …

Vibrational Characterization Of Granulosa Cells From Patients Affected By Unilaterial Ovarian Endometriosis: New Insights From Infrared And Raman Microspectroscopy, Valentina Notarstefano, Giorgia Gioacchini, Hugh Byrne, Carlotta Zaca, Eleni Sereni, Lisa Vaccari, Andrea Borini, Oliana Carnevali

Articles

Endometriosis is a chronic gynaecological disease characterised by the presence of endometrial cells in extra-uterine regions. One of the main factors impacting on the fertility of women affected by endometriosis is the poor oocyte quality. Granulosa Cells (GCs) regulate oocyte development and maintain the appropriate microenvironment for the acquisition of its competence; hence, the dysregulation of these functions in GCs can lead to severe cellular damages also in oocytes. In this study, luteinized GCs samples were separately collected from both ovaries of women affected by Unilateral Ovarian Endometriosis and analysed by infrared and Raman microspectroscopy. The spectral data were compared …

Analysis Of Bodily Fluids Using Vibrational Spectroscopy: A Direct Comparison Of Raman Scattering And Infrared Absorption Techniques For The Case Of Glucose In Blood Serum, Drishya Prachalil, Clément Bruno, Franck Bonnier, Helen Blasco, Igor Chourpa, Matthew Baker, Jennifer Mcintyre, Hugh Byrne

Articles

Analysis of biomarkers present in the blood stream can potentially deliver crucial information on patient health and indicate the presence of numerous pathologies. The potential of vibrational spectroscopic analysis of human serum for diagnostic purposes has been widely investigated and, in recent times, infrared absorption spectroscopy, coupled with ultra-filtration and multivariate analysis techniques, has attracted increasing attention, both clinical and commercial. However, such methods commonly employ a drying step, which may hinder the clinical work flow and thus hamper their clinical deployment. As an alternative, this study explores the use of Raman spectroscopy, similarly coupled with ultra-filtration and multivariate analysis …

Improved Performance Of Near Infrared Excitation Raman Spectroscopy Using Reflective Thin-Film Gold On Glass Substrates For Cytology Samples, Sinead Barton, Kevin O'Dwyer, Marion Butler, Hugh Byrne, Luke O'Neill, Bryan M. Hennelly

Articles

Confocal near-infrared Raman spectroscopy has been shown to have applications in the area of clinical biology. A source wavelength in the near infrared is preferred over visible wavelengths for inspecting biological samples due to superior wave number resolution and reduced photo damage. However, these excitation sources have a number of drawbacks when compared to lasers in the visible wavelength region, including the requirement to use expensive highly pure crystal substrates such as Raman grade calcium fluoride as well as long acquisition times due to the lower Raman scattering efficiency. This paper investigates the use of a reflective substrate comprising a …

Numerically Modelling Time And Dose Dependent Cytotoxicity, Hugh Byrne, Marcus A. Maher

Articles

Dose-response curves are fundamental tools of in vitro toxicology, extensively employed in toxicant or drug screening. They are expressed by a variety of end-points and assays, measured at different time-points in a choice of cell-lines, but are typically quantified only using the mean concentration for 50% response (e.g. drug efficacy or pathway inhibition) as an indicator of overall effect. However, the response is the result of a complex and dynamic cascade of events which occur between the initial exposure and the measured end-point, and the characteristic rates of the contributing stages govern the dose response and ultimately the measured characteristic …

Human Rights And Precarious Workplaces: A Comment On British Columbia Human Rights Tribunal V Schrenk Case Comments

UBC Law Review

No abstract provided.

The Science, Law, And Politics Of Canada's Pathways To Paris: Introduction To Ubc Law Review's Special Section On Canada And Climate Change Special Section: Canada And Climate Change

UBC Law Review

No abstract provided.

The Role Of Science In Contemporary Canadian Environmental Decision Making: The Example Of Environmental Assessment Special Section: Canada And Climate Change

UBC Law Review

No abstract provided.

In Search Of An Ecological Approach To Constitutional Principles And Environmental Discretion In Canada Special Section: Canada And Climate Change

UBC Law Review

No abstract provided.

Productive Response To Two Concentrate Allocation Strategies In Dairy Cows Grazing With Restricted Pasture Allowance, Gustavo Bretschneider, Eloy Salado, Alejandra Cuatrin, Juan Mattera, Mariela Pece, Dario Arias, Maira Cuffia, Virginia Dieguez

Turkish Journal of Veterinary & Animal Sciences

The objective of this study was to compare the effects of two concentrate allotment strategies on the performance of dairy cows grazing on restricted pasture and supplemented with conserved forage. Dairy cows fed equal amounts of concentrate (fixed daily rate: 5.5 kg DM/cow) were compared to cows supplemented with concentrate according to their lactation stage as follows: 10.0, 5.0, and 1.5 kg DM/cow daily during early, mid, and late lactation, respectively (average daily dose: 5.5 kg DM/cow). There was a supplementation strategy × lactation stage interaction (P < 0.05) for energy-corrected milk (ECM). For early lactation cows, supplementation at a variable rate increased ECM yield by 14.61% (P < 0.05). There was a supplementation strategy × lactation stage interaction (P < 0.05) for body weight change. At late lactation stage, cows supplemented at a fixed rate gained weight (+ 0.16 kg/day), whereas those supplemented at a variable rate lost weight (- 0.08 kg/day; P < 0.05). No significant effect was found for body condition score. The prioritization of milk production rather than the attenuation of body reserve mobilization suggests that concentrate allowance based on lactation stage may be unsuitable for minimizing the negative energy balance in early lactation cows.

Hematologic, Biochemical, Genetic, And Histological Biomarkers For The Evaluation Of The Toxic Effects Of Fipronil For Rhamdia Quelen, Ana Carolina Fredianelli, Victor Hugo Pierin, Samara Caroline Uhlig, Luciana Do Amaral Gurgel Galeb, Daniel Carlos Coatti Rocha, Deivid Roni Ribeiro, Amanda Anater, Claudia Turra Pimpão

Turkish Journal of Veterinary & Animal Sciences

This study aimed to determine the lethal concentration 50% (LC$_{50}$) and behavioral, hematological, biochemical, histopathological, and genetic disorders of fipronil for Rhamdia quelen in acute toxicity tests for 96 h. To determine the LC$_{50}$, 42 juveniles were distributed in groups of 0, 0.1, 0.2, 0.3, 0.4, 0.5, and 0.8 mg L$^{-1}$ of fipronil. For other evaluations 36 silver catfish were divided into control, 0.3 mg L$^{-1}$, and 0.4 mg L$^{-1}$ groups. Blood, kidneys, livers, and gills were collected for evaluation. The LC$_{50}$ calculated with probit-type regression was 0.811 mg L$^{-1}$ at 48 h of study. There was total mortality of …

Microsatellite Panels For Parentage Testing Of Kilis Goats Reared In Turkey, Mahmut Keski̇n, Onur Yilmaz, Zühal Gündüz, Nezi̇h Ata, Sabri̇ Gül, İbrahi̇m Cemal, Orhan Karaca, Süleyman Ercüment Önel

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to develop PCR-based suitable microsatellite marker panels for paternity testing and to define pedigree errors in Kilis goats. A total of 137 head of goats were used, consisting of 118 head of kids and 19 head of possible candidate sires. A total of 392 alleles were observed in 22 microsatellite markers. Allele numbers ranged between 12 (SRCRSP7) and 24 (BM1818, INRA0023, and SRCRSP15) with an average of 17.82. The mean value of the effective allele numbers was obtained as 9.44. The overall polymorphic information content value was quite high (0.88). The overall observed (Ho) …

Phylogenetic Relationships Of Native Turkish Cattle Breeds Using Microsatellite Markers, Yusuf Özşensoy, Ercan Kurar, Müge Doğan, Zafer Bulut, Mehmet Ni̇zamlioğlu, Ayşe Işik, Aysun Çamlidağ, Vahdetti̇n Altunok

Turkish Journal of Veterinary & Animal Sciences

A total of 20 microsatellite DNA markers were used for genetic characterization and determination of phylogenetic relationships of native cattle breeds of Turkey, including the Anatolian Grey (AG), Anatolian Black (AB), South Anatolian Red (SAR), East Anatolian Red (EAR), Southern Anatolian Yellow (SAY), and Zavot (ZAV). DNA samples were isolated from 271 blood samples using an organic method. Amplified polymerase chain reaction products were separated by capillary electrophoresis and genotypes were determined for 20 microsatellites. A total of 269 different alleles were determined. The lowest (7.80) and highest (10.80) mean allele numbers were observed for the ZAV and SAY populations, …

A Case Of Ex Vivo Boosted Immune Cell Therapy For Chronic Ulcerative Dermatitis In A Dog, Seulgi Bae

Turkish Journal of Veterinary & Animal Sciences

A 13-year-old castrated male Shih Tzu was presented with recurrent otitis externa and ulcerative dermatitis. Previous investigations had failed to identify the cause, and the lesion was resistant to treatment. According to the histopathological examination, a tentative diagnosis of chronic ulcerative dermatitis with bacterial infection was made. To treat the patient, immune cell therapy with antibiotics was conducted every 2 weeks, for a total of six sessions. After treatment, the skin lesion resolved. No side effects were observed during therapy. To the best of our knowledge, this is the first case report of the use of immune cell therapy for …

Influence Of Rearing Conditions And Birth Season On Calf Welfare In The First Month Of Life, Ljiljana Samolovac, Slavca Hristov, Branislav Stankovic, Radojka Maletic, Renata Relic, Zvonko Zlatanovic

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to analyze the influence of farm conditions and season of birth on body mass, respiratory system diseases and diarrhea occurrence, and mortality during the first month of calves? life. The study was conducted on two tie-stall-system farms with intensive milk production and similar nutrition of dairy cows, but with differences in rearing conditions of calves in the first week of life. The calves were tied on lying area with straw as bedding material (farm A) or free in individual boxes with straw bedding (farm B). In the first consumption, they take 1-2 L of …

The Influence Of Haptoglobin Phenotype On Differential Leukocyte Count In Neonatal Calves, Elena Kalaeva, Olga Zemlyanukhina, Vladislav Kalaev, Kseniya Efimova, Anton Chernitskiy, Nikolay Kaverin, Vladimir Safonov

Turkish Journal of Veterinary & Animal Sciences

This research was conducted to study the content and phenotypes of haptoglobin and their correlation to the differential leukocyte count in healthy Red-motley Holstein calves (n = 30). The blood samples from calves were taken through puncture of the jugular vein on days 1, 7, 14, and 28 after birth. Differential leukocyte count was analyzed by manual enumeration. Serum haptoglobin content was determined by spectrophotometry (UV-1700 Shimadzu, Japan). Haptoglobin phenotypes were studied using gel electrophoresis. Serum haptoglobin content in calves on day 1 after birth was 3.8 ± 0.7 g/L, on day 7 was 3.5 ± 0.7 g/L, and on …

Sequence Characterization Of Full-Length S, Yeganeh Yousefi, Mohammad Reza Bassami, Gholam Ali Kalidari, Mohammad Mehdi Ghahramani Seno

Turkish Journal of Veterinary & Animal Sciences

Infectious bronchitis virus (IBV) causes heavy economic losses in chicken farms worldwide. Like many other viral diseases, vaccination is the gold standard approach in controlling and preventing the spread of IBV. However, IBV is continuously evolving and new strains of this virus emerge that, due to variable antigenic cross-reactivity, may reduce or nullify the protective effect of vaccination programs. Therefore, advance knowledge of the IBV strain(s) circulating in a region will be very useful in deciding which commercial vaccine(s) would be most effective. In this line, we analyzed the nucleotide sequence of the full-length 1$_{1}$ gene of IBV viruses isolated …

Management Of A Coxiella Burnetii-Infected Sheep Flock After An Outbreak Of Q Fever In Humans, Jana Avbersek, Mateja Pate, Andrej Skibin, Matjaz Ocepek, Brane Krt

Turkish Journal of Veterinary & Animal Sciences

Following an outbreak of Q fever in a group of students who contracted the infection during a training course on a sheep farm, a detailed investigation of the sheep flock involved was conducted. Of 478 flock animals, 60 Coxiella burnetii ELISA-positive and 60 ELISA-negative ewes were selected for the trial and divided into four groups. A month after the initial ELISA screening, all ewes in the flock (except the control group) were vaccinated. Sequentially collected blood samples were tested with ELISA and PCR; feces, milk, manure, bedding, and soil were tested with PCR. The immune response to the vaccination was …

Negative Effects Of Occurrence Of Clinical Mastitis From Calving To End Of The Voluntary Waiting Period On Reproduction In Holstein Cows, Seçki̇n Salar, Oğuz Çalişici, Duygu Çalişici, Doğukan Özen, Ayhan Baştan

Turkish Journal of Veterinary & Animal Sciences

The objective was to evaluate the effects of clinical mastitis (CM) on reproductive performance in high-milk?producing cows before the service period. The data of Holstein Friesian cows (n = 550) in a commercial farm was retrospectively evaluated. The diagnosis of CM was made by the presence of visible abnormalities in milk or symptoms of inflammation of one or more of the quarters. Cows were checked to detect CM prior to each milking. Calving to first service interval (CFSI), calving to conception interval (CCI), and services per conception (SC) were evaluated as reproductive parameters. Calving to first service interval (83.68 ± …

Formation Of Local Protection Of The Respiratory Tract In Holstein Calves, Yuriy Alekhin, Maksim Zhukov, Valentina Morgunova, Galina Chusova, Irina Klementeva

Turkish Journal of Veterinary & Animal Sciences

The processes of formation of the local protection of the respiratory tract in nasal secretion samples of Holstein calves from birth to 6 months of age that were born from clinically healthy cows were examined. Only clinically healthy animals were involved in the experiment. Nasal secretion samples were collected with the help of a sterile foam tampon with a fixing thread in order to assess local immunity in animals at the age of 1, 5, 10, 30, 60, 90, 120, 150, and 180 days. Total protein, mucin, lysozyme activity, and alkaline phosphatase (ALP) were determined using commercially available methods. The …

The Effect Of Laying Period On Egg Quality Traits And Chemical Composition Of Lindovskaya (Linda) Geese Reared Under Breeder Conditions, Mehmet Sari, Kadi̇r Emre Buğdayci, Aykut Asim Akbaş, Mustafa Saatci, Mustafa Numan Oğuz

Turkish Journal of Veterinary & Animal Sciences

The study was conducted to determine the effect of laying period on egg quality traits as well as the chemical composition of Lindovskaya geese. The egg quality traits were examined by randomly taking a total of 90 eggs on the 45th ± 5, 60th ± 5, and 75th ± 5 days of the laying period from 3-year-old female Lindovskaya geese. It was determined that the effect of the laying period on external quality traits of eggs was statistically nonsignificant (P > 0.05). The effect of laying period on internal quality traits including height, diameter, and index of the yolk and albumen …

Neutralizing Antibody Titers Against Field Strains Of Bovine Viral Diarrhea Virus After Vaccination With Three Commercial Vaccines, Gi̇zem Alpay, Kadi̇r Yeşi̇lbağ

Turkish Journal of Veterinary & Animal Sciences

Modified killed vaccines against bovine viral diarrhea virus (BVDV) are used worldwide. In the present study, the cross-neutralization antibody responses against field strains from seven subgenotypes of BVDV-1 and one subgenotype of BVDV-2 were evaluated using sera obtained by three inactivated commercial vaccines. One vaccine contained both BVDV-1 and BVDV-2 strains, while the others contained only BVDV-1a. Three vaccine groups, each containing five calves, were vaccinated two times with 30-day intervals. The antibody titers were evaluated by virus neutralization assay. The monovalent vaccine induced the highest antibody titers. Significant levels of neutralizing antibody titers were maintained up to the last …

Histomorphological And Histochemical Structure Of The Midgut And Hindgut Of The Caucasian Honey Bee (Apis Mellifera Caucasia), Ahmet Ceylan, Sedat Sevi̇n, Özge Özgenç

Turkish Journal of Veterinary & Animal Sciences

The Caucasian honey bee (Apis mellifera caucasia subspecies of Apis mellifera L.) is one of the most common and prominent honey bee breeds in Turkey. The morphometry of endemic honey bee breeds has been extensively studied, but little attention has been given to the microscopic morphology of these bees. The aim of the current study was to describe for the first time the histomorphology of the midgut and hindgut of the Caucasian honey bee in Turkey. A total of 20 local Caucasian adult honey bee workers were sampled for histomorphological and histochemical analysis. The midgut epithelium consisted of epithelial cells …

Development Of Spermatogonial Stem Cell Niche And Immunoexpression Of Vimentin Filaments In The Testes Of Prenatal And Postnatal Indian Buffalo (Bubalus Bubalis), Ashritha Quanisha Carlo, Devendra Pathak, Opinder Singh, Neelam Bansal

Turkish Journal of Veterinary & Animal Sciences

In this study, we established the components of the buffalo spermatogonial stem cell (SSC) niche in prenatal (38.5-280 days of gestation), neonatal, prepubertal, and adult testes histochemically and immunohistochemically. Immunohistochemically, the changes in vimentin expression were evaluated. During prenatal life, the niche of primordial germ cells was formed by the surrounding mesenchymal cells and fibroblasts. The basement membrane (BM) was not organized at this stage. At 7.6 cm crown-rump length, testicular cords with a thin BM were seen. At the late gestational period, testicular cords with well-organized BM were seen. At the neonatal stage, the testicular cords were lined with …

Phenotypic Characterization And Differentiation Of Mesenchymal Stem Cells Originating From Adipose Tissue, Ece Çerçi̇, Hati̇ce Erdost

Turkish Journal of Veterinary & Animal Sciences

Stem cells are known as undifferentiated cells that are capable of divisions and self-renewal over an extended period. Adipose tissue-derived mesenchymal stem cells (ADSCs) are known to differentiate into many different organ and tissue cells. The purpose of this study was to characterize adipose tissue-derived mesenchymal stem cells in detail based on the expression status of certain surface markers and differentiation stages for clinical and laboratory applications. The migrating phase and mitotic property of the cells from adipose tissue were assessed under a microscope. Cell counting was performed during the first, second, and third passages. The cells were differentiated into …

Rehabilitation Tenure And Promotion Criteria, Department Of Rehabilitation, East Tennessee State University

Tenure and Promotion Criteria

No abstract provided.