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2019

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Evaluation Of A Countywide Alternative To Qof, Aimed At Improving Person-Centred Coordinated Care, J Close, B Fosh, R Byng, R Blackwell, L Witts, L Hall, H Lloyd Jan 2019

Evaluation Of A Countywide Alternative To Qof, Aimed At Improving Person-Centred Coordinated Care, J Close, B Fosh, R Byng, R Blackwell, L Witts, L Hall, H Lloyd

Peninsula Medical School

No abstract provided.


Measuring Aberrations Of Multifocal And Extended Depth-Of-Focus Intraocular Lenses, Aguila-Carrasco A Del, Eleni Papadatou, Phillip J. Buckhurst Jan 2019

Measuring Aberrations Of Multifocal And Extended Depth-Of-Focus Intraocular Lenses, Aguila-Carrasco A Del, Eleni Papadatou, Phillip J. Buckhurst

School of Health Professions

No abstract provided.


Safeguarding Children And The Use Of Theory In Practice, Pa Welbourne Jan 2019

Safeguarding Children And The Use Of Theory In Practice, Pa Welbourne

School of Health Professions

No abstract provided.


An Evaluation Of The Fishing For Litter (Ffl) Scheme In The Uk In Terms Of Attitudes, Behavior, Barriers And Opportunities, Kayleigh J. Wyles, Sabine Pahl, Lauren Carroll, Richard C. Thompson Jan 2019

An Evaluation Of The Fishing For Litter (Ffl) Scheme In The Uk In Terms Of Attitudes, Behavior, Barriers And Opportunities, Kayleigh J. Wyles, Sabine Pahl, Lauren Carroll, Richard C. Thompson

School of Psychology

No abstract provided.


Social Evaluation Of Faces Across Gender And Familiarity, Mila Mileva, Robin S.S. Kramer, A. Mike Burton Jan 2019

Social Evaluation Of Faces Across Gender And Familiarity, Mila Mileva, Robin S.S. Kramer, A. Mike Burton

School of Psychology

Models of social evaluation aim to capture the information people use to form first impressions of unfamiliar others. However, little is currently known about the relationship between perceived traits across gender. In Study 1, we asked viewers to provide ratings of key social dimensions (dominance, trustworthiness, etc.) for multiple images of 40 unfamiliar identities. We observed clear sex differences in the perception of dominance—with negative evaluations of high dominance in unfamiliar females but not males. In Study 2, we used the social evaluation context to investigate the key predictions about the importance of pictorial information in familiar and unfamiliar face …


Understanding Student Charters Through Psychological Contracts In Higher Education: A Grounded Theory Approach, Julie Ann Osborn Jan 2019

Understanding Student Charters Through Psychological Contracts In Higher Education: A Grounded Theory Approach, Julie Ann Osborn

Other Faculty of Health Theses

The introduction of higher fees and globalisation have created a competitive environment in which UK universities operate. Higher fees and globalisation have placed emphasis on higher education institutions operating as a profit driven sector with feedback sought from consumers in the form of large scale surveys e.g. National Student Survey (NSS). Our understanding of the student experience has been framed within a broadly positivist framework, which arguably limits our understanding. The purpose of this study was to trial a new way of exploring the student experience. This novel approach used the psychological contract as a sensitising concept. It has been …


Effect Of Phytoestrogens On Breast And Prostate Cancer Cell Lines – Potential Implications For Bone Metastasis, Safaa Salman Mezban Al-Thamiree Jan 2019

Effect Of Phytoestrogens On Breast And Prostate Cancer Cell Lines – Potential Implications For Bone Metastasis, Safaa Salman Mezban Al-Thamiree

Other Faculty of Health Theses

The effect of phytoestrogens on breast and prostate cancer cell lines – potential implications for bone preferential metastasis to bone Safaa Salman Mezban AL-Thamiree Abstract Many epidemiological studies indicate that diets rich in phytoestrogens (PE), especially soy and grain products, may be associated with a lower risk of some steroid hormone-dependent cancers such as breast and prostate. In particular PE have been shown to reduce the incidence of skeletal metastasis which have a high degree of morbidity and mortality. However, the most effective combinations of PEs and the mechanism through which they may reduce bone metastasis remain unclear. Therefore, this …


Exploring The Sensitivity Of Mantle Cell Lymphoma To Inhibitors Of Bruton’S Tyrosine Kinase, Hannah Patricia Thompson Jan 2019

Exploring The Sensitivity Of Mantle Cell Lymphoma To Inhibitors Of Bruton’S Tyrosine Kinase, Hannah Patricia Thompson

Other Faculty of Health Theses

EXPLORING THE SENSITIVITY OF MANTLE CELL LYMPHOMA TO INHIBITORS OF BRUTON’S TYROSINE KINASE Mantle cell lymphoma (MCL) is an incurable B-cell lymphoma which responds poorly to conventional chemotherapy. Inhibitors of Bruton’s tyrosine kinase (BTKi) have shown a significant clinical effect; despite this success however, approximately one third of MCL patients have primary resistance to the drug, and patients who initially respond to treatment frequently acquire secondary resistance with aggressive relapse of the disease. The purpose of this study was to understand how BTKi-resistance or sensitivity is mediated, aiming to identify new targets for therapy or predictive biomarkers of response. Combining …


Relationship Of Nocturnal Sleep Dysfunction And Pain Subtypes In Parkinson's Disease, Pablo Martinez-Martin, Alexandra M. Rizos, John B. Wetmore, Angelo Antonini, Per Odin, Suvankar Pal, Rani Sophia, Camille Carroll, Davide Martino, Cristian Falup-Pecurariu, Belinda Kessel, Thomasin Andrews, Dominic Paviour, Claudia Trenkwalder, Kallol Ray Chaudhuri Jan 2019

Relationship Of Nocturnal Sleep Dysfunction And Pain Subtypes In Parkinson's Disease, Pablo Martinez-Martin, Alexandra M. Rizos, John B. Wetmore, Angelo Antonini, Per Odin, Suvankar Pal, Rani Sophia, Camille Carroll, Davide Martino, Cristian Falup-Pecurariu, Belinda Kessel, Thomasin Andrews, Dominic Paviour, Claudia Trenkwalder, Kallol Ray Chaudhuri

Peninsula Medical School

© 2018 International Parkinson and Movement Disorder Society Background: Little research has been conducted regarding the relationship between sleep disorders and different pain types in Parkinson's disease (PD). Objective: To explore the influence of the various pain subtypes experienced by PD patients on sleep. Methods: Three hundred consecutive PD patients were assessed with the PD Sleep Scale-Version 2 (PDSS-2), King's PD Pain Scale (KPPS), King's PD Pain Questionnaire (KPPQ), Visual Analog Scales for Pain (VAS-Pain), and Hospital Anxiety and Depression Scale. Results: According to the PDSS-2, 99.3% of our sample suffered from at least one sleep issue. Those who reported …


Refractory Depression – Cost-Effectiveness Of Radically Open Dialectical Behaviour Therapy: Findings Of Economic Evaluation Of Reframed Trial, James Shearer, Thomas R. Lynch, Rampaul Chamba, Susan Clarke, Roelie J. Hempel, David G. Kingdon, Heather O'Mahen, Bob Remington, Sophie C. Rushbrook, Ian T. Russell, Maggie Stanton, Michaela Swales, Alan Watkins, Ben Whalley, Sarah Byford Jan 2019

Refractory Depression – Cost-Effectiveness Of Radically Open Dialectical Behaviour Therapy: Findings Of Economic Evaluation Of Reframed Trial, James Shearer, Thomas R. Lynch, Rampaul Chamba, Susan Clarke, Roelie J. Hempel, David G. Kingdon, Heather O'Mahen, Bob Remington, Sophie C. Rushbrook, Ian T. Russell, Maggie Stanton, Michaela Swales, Alan Watkins, Ben Whalley, Sarah Byford

School of Psychology

BackgroundRefractory depression is a major contributor to the economic burden of depression. Radically open dialectical behaviour therapy (RO DBT) is an unevaluated new treatment targeting overcontrolled personality, common in refractory depression, but it is not yet known whether the additional expense of RO DBT is good value for money.AimsTo estimate the cost-effectiveness of RO DBT plus treatment as usual (TAU) compared with TAU alone in people with refractory depression (trial registration: ISRCTN85784627).MethodWe undertook a cost-effectiveness analysis alongside a randomised trial evaluating RO DBT plus TAU versus TAU alone for refractory depression in three UK secondary care centres. Our economic evaluation, …


How Group-Based Interventions Can Improve Services For People With Severe Obesity, Dawn Swancutt, Mark Tarrant, Jonathan Pinkney Jan 2019

How Group-Based Interventions Can Improve Services For People With Severe Obesity, Dawn Swancutt, Mark Tarrant, Jonathan Pinkney

Peninsula Medical School

No abstract provided.


Statins And Parkinson's: A Complex Interaction, Camille B. Carroll, Richard K.H. Wyse, Donald G. Grosset Jan 2019

Statins And Parkinson's: A Complex Interaction, Camille B. Carroll, Richard K.H. Wyse, Donald G. Grosset

Peninsula Medical School

No abstract provided.


The Perceived Effectiveness Of Brief Psychological Techniques For Acute Postoperative Pain, Alsanaani Tahani Jan 2019

The Perceived Effectiveness Of Brief Psychological Techniques For Acute Postoperative Pain, Alsanaani Tahani

Other Faculty of Health Theses

Postoperative pain is still a challenge and patients are still suffering from postoperative pain, despite the administration of multiple analgesic methods for treating pain. In a systematic review and meta-analysis I found that brief psychological interventions such as relaxation techniques including simple breathing exercises or guided imagery, and simple distraction techniques such as listening to music, or practicing a script of self-hypnosis may help those patients to cope better with their pain. Although quality of these studies was not always of the highest level, the findings synthesized from 30 randomised controlled trials indicated that brief psychological interventions did reduce postoperative …


Governance Through Diversion In Neoliberal Times And The Possibilities For Transformative Social Justice, Patricia Gray, Roger Smith Jan 2019

Governance Through Diversion In Neoliberal Times And The Possibilities For Transformative Social Justice, Patricia Gray, Roger Smith

School of Law, Humanities and Social Sciences

Over the last decade, the dramatic increase in the number of young people diverted from formal processing through the youth justice system in England and Wales, and the equally sharp drop in the rate of youth custody suggest that the neoliberal formula for the penal governance of young people who offend has been undergoing significant reshaping. This article draws on research which interrogates the changes that are currently taking place, particularly the proliferation of “out of court” community-based measures of diversion and offense resolution, to develop a more fine-tuned conceptualization of the complexities of neoliberal youth penality. We base our …


Changes In Marine Phytoplankton Diversity: Assessment Under The Marine Strategy Framework Directive, A. Mcquatters-Gollop, I. Rombouts Jan 2019

Changes In Marine Phytoplankton Diversity: Assessment Under The Marine Strategy Framework Directive, A. Mcquatters-Gollop, I. Rombouts

School of Biological and Marine Sciences

No abstract provided.


The Processing Of Compound Radial Frequency Patterns, Gunnar Schmidtmann, Frederick A.A. Kingdom, Gunter Loffler Jan 2019

The Processing Of Compound Radial Frequency Patterns, Gunnar Schmidtmann, Frederick A.A. Kingdom, Gunter Loffler

School of Health Professions

No abstract provided.


Radial Frequency Patterns Describe A Small And Perceptually Distinct Subset Of All Possible Planar Shapes, Gunnar Schmidtmann, Ingo Fruend Jan 2019

Radial Frequency Patterns Describe A Small And Perceptually Distinct Subset Of All Possible Planar Shapes, Gunnar Schmidtmann, Ingo Fruend

School of Health Professions

No abstract provided.


Imi - Clinical Myopia Control Trials And Instrumentation Report, James S. Wolffsohn, Pete S. Kollbaum, David A. Berntsen, David A. Atchison, Alexandra Benavente, Arthur Bradley, Hetal Buckhurst, Michael Collins, Takashi Fujikado, Takahiro Hiraoka, Masakazu Hirota, Debbie Jones, Nicola S. Logan, L Lundstrom, Hidemasa Torii, Scott A. Read, Kovin Naidoo Jan 2019

Imi - Clinical Myopia Control Trials And Instrumentation Report, James S. Wolffsohn, Pete S. Kollbaum, David A. Berntsen, David A. Atchison, Alexandra Benavente, Arthur Bradley, Hetal Buckhurst, Michael Collins, Takashi Fujikado, Takahiro Hiraoka, Masakazu Hirota, Debbie Jones, Nicola S. Logan, L Lundstrom, Hidemasa Torii, Scott A. Read, Kovin Naidoo

School of Health Professions

No abstract provided.


Faith-Based Support For Alzheimer's Family Caregivers In Madison County, Alabama, Meredith Lewis Jan 2019

Faith-Based Support For Alzheimer's Family Caregivers In Madison County, Alabama, Meredith Lewis

Walden Dissertations and Doctoral Studies

Alzheimer's disease, the sixth leading cause of death in the United States, is incurable. Because of the extensive long-term care required for patients with Alzheimer's, the typical caregiver is often a middle-aged family member with his or her own health problems. The purpose of this quantitative cross-sectional study was to determine the extent to which there was a difference in the perception of quality of life between Alzheimer's family caregivers who receive tangible faith-based support compared to the Alzheimer's family caregivers who receive no social support. The theoretical basis was social support theory, which suggests that support buffers stress. The …


Small Business Responses To Reduce Impacts From Natural Disasters, Lenox Lemar Godfrey Jan 2019

Small Business Responses To Reduce Impacts From Natural Disasters, Lenox Lemar Godfrey

Walden Dissertations and Doctoral Studies

Florida is a hurricane-prone state, and not all small business owners are prepared to survive in the wake of a hurricane or flood event, as only 14% of small business owners prepare for natural disasters compared to 44.9% for large corporations. Small business owners can enhance the survivability of their companies with well prepared disaster plans. The purpose of this qualitative case study was to explore strategies 5 small business owners in northwest Florida implemented to avoid permanent business closure after a natural disaster. The conceptual framework was the theory of planned behavior. Data were collected through interviews with 5 …


Mice Fed An Obesogenic Western Diet, Administered Antibiotics, And Subjected To A Sterile Surgical Procedure Develop Lethal Septicemia With Multidrug-Resistant Pathobionts, Sanjiv K. Hyoju, Alexander Zaborin, Robert Keskey, Anukriti Sharma, Wyatt Arnold, Fons Van Den Berg, Sangman Michael Kim, Neil Gottel, Cindy Bethel, Angella Charnot-Katsikas, Peng Jianxin, Carleen Adriaansens, Emily Papazian, Jack A. Gilbert, Olga Zaborina, John C. Alverdy Jan 2019

Mice Fed An Obesogenic Western Diet, Administered Antibiotics, And Subjected To A Sterile Surgical Procedure Develop Lethal Septicemia With Multidrug-Resistant Pathobionts, Sanjiv K. Hyoju, Alexander Zaborin, Robert Keskey, Anukriti Sharma, Wyatt Arnold, Fons Van Den Berg, Sangman Michael Kim, Neil Gottel, Cindy Bethel, Angella Charnot-Katsikas, Peng Jianxin, Carleen Adriaansens, Emily Papazian, Jack A. Gilbert, Olga Zaborina, John C. Alverdy

Biology Faculty Publications

Despite antibiotics and sterile technique, postoperative infections remain a real and present danger to patients. Recent estimates suggest that 50% of the pathogens associated with postoperative infections have become resistant to the standard antibiotics used for prophylaxis. Risk factors identified in such cases include obesity and antibiotic exposure. To study the combined effect of obesity and antibiotic exposure on postoperative infection, mice were allowed to gain weight on an obesogenic Western-type diet (WD), administered antibiotics and then subjected to an otherwise recoverable sterile surgical injury (30% hepatectomy). The feeding of a WD alone resulted in a major imbalance of the …


Best Practice Guidelines For Training Professional Carers In The Administration Of Buccal (Oromucosal) Midazolam For The Treatment Of Prolonged And/Or Clusters Of Epileptic Seizures In The Community, Rohit Shankar Jan 2019

Best Practice Guidelines For Training Professional Carers In The Administration Of Buccal (Oromucosal) Midazolam For The Treatment Of Prolonged And/Or Clusters Of Epileptic Seizures In The Community, Rohit Shankar

Peninsula Medical School

No abstract provided.


Exploring Patients’ And Healthcare Professionals’ Experiences Of Patient-Witnessed Resuscitation: A Qualitative Study Protocol, Martina Fiori, Ruth Endacott, Jos M. Latour Jan 2019

Exploring Patients’ And Healthcare Professionals’ Experiences Of Patient-Witnessed Resuscitation: A Qualitative Study Protocol, Martina Fiori, Ruth Endacott, Jos M. Latour

School of Nursing and Midwifery

No abstract provided.


Effects Of Family-Centered Care Interventions On Preterm Infants And Parents In Neonatal Intensive Care Units: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials, Xiang Ding, Lihui Zhu, Rong Zhang, L Wang, T-T Wang, Jos M. Latour Jan 2019

Effects Of Family-Centered Care Interventions On Preterm Infants And Parents In Neonatal Intensive Care Units: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials, Xiang Ding, Lihui Zhu, Rong Zhang, L Wang, T-T Wang, Jos M. Latour

School of Nursing and Midwifery

Objective: To review English and Chinese randomized controlled trials (RCTs) to determine the effects of family-centered care interventions on preterm infants’ and parental outcomes in Neonatal Intensive Care Units and to conduct a meta-analysis. Review method used: Systematic review and meta-analysis. Data sources: MEDLINE, CINAHL, EMBASE, PsycInfo, BNI, AMED and the Chinese databases CNKI and Wanfang were searched in April 2017 and updated in August 2018. Review methods: Only RCTs were included. Participants were preterm infants ≤ 37 weeks gestational age and parents. Interventions were related to family-centered care and outcome measures were infant and parent clinical outcomes. Included studies …


From Mental Disorder To Shared Understanding: A Non-Categorical Approach To Support Individuals With Distress In Primary Care, Richard Byng, Nora Groos, Christopher Dowrick Jan 2019

From Mental Disorder To Shared Understanding: A Non-Categorical Approach To Support Individuals With Distress In Primary Care, Richard Byng, Nora Groos, Christopher Dowrick

Peninsula Medical School

This article argues that, rather than aiming for a psychiatric diagnosis, generalist professionals such as those working in primary care, as well as in other hospital and community settings, should use a non-diagnostic framework when encountering distress. The conceptual and empirical limitations of the psychiatric diagnostic system and evidence that psychological phenomena are dimensional suggest the need for an alternative approach; one that might also address problems of overdiagnosis and overmedication.1 There are three key problems with the current Diagnostic Statistical Manual (DSM) and International Classification of Diseases (ICD) systems of psychiatric classification. The process can be stigmatising; diagnoses are …


Evaluation Of The Impact Of The Nice Head Injury Guidelines On Inpatient Mortality From Traumatic Brain Injury: An Interrupted Time Series Analysis, Carl Marincowitz, Fiona Lecky, Victoria Allgar, Trevor Sheldon Jan 2019

Evaluation Of The Impact Of The Nice Head Injury Guidelines On Inpatient Mortality From Traumatic Brain Injury: An Interrupted Time Series Analysis, Carl Marincowitz, Fiona Lecky, Victoria Allgar, Trevor Sheldon

Peninsula Medical School

ObjectiveTo evaluate the impact of National Institute for Health and Care Excellence (NICE) head injury guidelines on deaths and hospital admissions caused by traumatic brain injury (TBI).SettingAll hospitals in England between 1998 and 2017.ParticipantsPatients admitted to hospital or who died up to 30 days following hospital admission with International Classification of Diseases (ICD) coding indicating the reason for admission or death was TBI.InterventionAn interrupted time series analysis was conducted with intervention points when each of the three guidelines was introduced. Analysis was stratified by guideline recommendation specific age groups (0–15, 16–64 and 65+).Outcome measuresThe monthly population mortality and admission rates …


Do Psychological Factors Relate To Energy Saving Behaviours In Inefficient And Damp Homes? A Study Among English Social Housing Residents, C Boomsma, Rv Jones, S Pahl, A Fuertes Jan 2019

Do Psychological Factors Relate To Energy Saving Behaviours In Inefficient And Damp Homes? A Study Among English Social Housing Residents, C Boomsma, Rv Jones, S Pahl, A Fuertes

School of Psychology

Social housing residents are vulnerable to rising energy costs. Reductions in energy use through behaviour change may be part of the solution but require an insight into the factors that relate to energy saving behaviour in this context. This paper responds to recent calls for an integrated approach to studying energy saving behaviours, investigating psychological (i.e. attitudes; perceived behavioural control; subjective norms), contextual (i.e. dwelling energy efficiency; problems with condensation, damp and mould), and socio-demographic factors (i.e. gender; age) together. Data was collected using a cross-sectional survey among social housing residents in South-West England. Dwelling characteristics were not found to …


Are Some Natural Environments More Psychologically Beneficial Than Others? The Importance Of Type And Quality On Connectedness To Nature And Psychological Restoration, Kayleigh J. Wyles, Mathew P. White, Caroline Hattam, Sabine Pahl, Haney King, Melanie Austen Jan 2019

Are Some Natural Environments More Psychologically Beneficial Than Others? The Importance Of Type And Quality On Connectedness To Nature And Psychological Restoration, Kayleigh J. Wyles, Mathew P. White, Caroline Hattam, Sabine Pahl, Haney King, Melanie Austen

School of Psychology

No abstract provided.


The Core-10 In Screening For Current Mental Health Problems And Severe Mental Illness In Prisoners, Gwen O'Connor, Reg Morris Jan 2019

The Core-10 In Screening For Current Mental Health Problems And Severe Mental Illness In Prisoners, Gwen O'Connor, Reg Morris

School of Psychology

No abstract provided.


The Importance Of Inter‐Individual Variation In Predicting Species' Responses To Global Change Drivers, Ella Guscelli, John I. Spicer, Piero Calosi Jan 2019

The Importance Of Inter‐Individual Variation In Predicting Species' Responses To Global Change Drivers, Ella Guscelli, John I. Spicer, Piero Calosi

School of Biological and Marine Sciences

No abstract provided.