Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2019

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 59731 - 59760 of 65715

Full-Text Articles in Entire DC Network

Wireless Smart Bandage For Real-Time Monitoring And Healing Of Chronic Wounds, Ting Zhang Jan 2019

Wireless Smart Bandage For Real-Time Monitoring And Healing Of Chronic Wounds, Ting Zhang

All ETDs from UAB

Chronic wound recovery time is long and easy to recur, which brings a high burden on the patient's physical and psychological aspects. The increase in the cost of per capita medical services and the increase in the number of people in demand for medical services have led to an increasing requirement for real-time monitoring and healing in patient's health outside of the hospital. For this purpose, the smart bandage is being developed to monitor the real-time situation of the wound. With the development of wireless sensor networks, the increasing number of sensing units has placed a great burden on the …

Go to article

Self-Tracking Practices: The Roles Of Social Contexts And Chronic Conditions, Aowen Zhu Jan 2019

Self-Tracking Practices: The Roles Of Social Contexts And Chronic Conditions, Aowen Zhu

All ETDs from UAB

The rapid development of mobile health (mHealth) technologies is propelled by the culture of disease prevention and management. Smartphone applications and wearable devices provide valuable personal data for self enhancement. In addition to health promotion, people with chronic conditions are using apps and devices to monitor symptoms and behaviors. There is great potential for self-tracking practices to reduce health care cost and improve population health. However, the emphasis on personal responsibility of individuals’ health may hinder the long-term effectiveness of self-tracking practices. The purpose of the study is to examine the associations between social contexts and self-tracking practices, chronic health …

Go to article

Time Trends In The Prevalence Of Diagnosed Sialolithiasis From Taiwanese Nationwide Health Insurance Dental Dataset, Yu-Hsun Wang, Yi-Tzu Chen, Yu-Wei Chiu, Hui-Chieh Yu, Yu-Chao Chang Jan 2019

Time Trends In The Prevalence Of Diagnosed Sialolithiasis From Taiwanese Nationwide Health Insurance Dental Dataset, Yu-Hsun Wang, Yi-Tzu Chen, Yu-Wei Chiu, Hui-Chieh Yu, Yu-Chao Chang

Journal of Dental Sciences

Abstract Background/Purpose Sialolithiasis, the so-called salivary gland stone, is a condition forming salivary calculi within a salivary gland or ducts. Little is known about the epidemiological survey of sialolithiasis in Taiwanese population. In this study, we conducted an age-period-cohort (APC) analysis evaluating the prevalence of sialolithiasis. Materials and methods A retrospective study was conducted to analyze the registered database compiled by the Taiwanese National Health Insurance Research Database from 1996 to 2013. The APC analysis was performed to investigate the effects of age, diagnosis period, and birth cohort with sialolithiasis. Results We found that the prevalence of sialolithiasis varied from …

Go to article

Therapeutic Potentials Of Oral Health Instructions In Periodontitis Patients With Diabetes Mellitus: Glycemic Control And Beyond, Chih-Wei Tseng, Kuo-Ching Lu, Chun-Jen Huang Jan 2019

Therapeutic Potentials Of Oral Health Instructions In Periodontitis Patients With Diabetes Mellitus: Glycemic Control And Beyond, Chih-Wei Tseng, Kuo-Ching Lu, Chun-Jen Huang

Journal of Dental Sciences

No abstract provided.

Go to article

Significance Of Acculturation, Assimilation, And Allostatic Load As Risk Factors For Obesity Among Hispanics, Yenni Elvia Cedillo Juare Jan 2019

Significance Of Acculturation, Assimilation, And Allostatic Load As Risk Factors For Obesity Among Hispanics, Yenni Elvia Cedillo Juare

All ETDs from UAB

Obesity has increased during the last two decades in the United States (U.S.) and is considered a major risk factor for chronic diseases within the Hispanic community. The burden of obesity in Hispanics is associated with higher rates of morbidity and mortality and an increase in healthcare costs. Hispanics’ challenges after migration extend to subsequent generations, putting the population at risk for disease development. Specifically, migration can lead to the adoption of health behaviors, beliefs, values, and language of the host country, a process known as acculturation, which has been associated with changes in health behaviors. Among the Hispanic population, …

Go to article

Personal, Environmental, And Behavioral Factors Of Condom Use Among African American Adolescent Males, Jessica Thames Chambliss Jan 2019

Personal, Environmental, And Behavioral Factors Of Condom Use Among African American Adolescent Males, Jessica Thames Chambliss

All ETDs from UAB

Risky sexual behaviors among adolescents increase the negative outcomes of the occurrence of an unplanned pregnancy and contracting or transmitting disease. Adoles- cents that engage in risky sexual activities are at greater risk for adverse health and social outcomes. Unfortunately, the impact of pregnancy and sexually transmitted infections (STIs) among adolescents is far-reaching and does not only affect the immediate individuals. Despite a decline in teen pregnancy and birth rates, the diagnosis of STIs is steadily increasing among adolescents. Moreover, African American adolescent males in the United States and specifically in Alabama are disproportionally more at risk for STIs. Additionally, …

Go to article

Sexual Behaviors And Non-Initiation Of The Hpv Vaccine Among Young Adult Cancer Survivors, Brooke Cherven Jan 2019

Sexual Behaviors And Non-Initiation Of The Hpv Vaccine Among Young Adult Cancer Survivors, Brooke Cherven

All ETDs from UAB

Advances in treatment for childhood cancer have led to increased survival rates. There are currently an estimated 400,000 survivors of childhood cancer living in the United States who are at risk for developing subsequent malignancies, including cancers associated with the human papillomavirus (HPV). HPV is the most common sexually transmitted infection; sexual behaviors associated with increased risk for HPV acquisition include younger age at first intercourse, multiple sexual partners, and inconsistent condom use. The prevalence of high-risk sexual behaviors, and the relationship between sexual behaviors and HPV vaccine non-initiation among young adult cancer survivors is unknown. This study used data …

Go to article

Examining Naloxone Access: A Spatial Asessment Of Opioid Use In Urban And Rural Contexts, Keith Chichester Jan 2019

Examining Naloxone Access: A Spatial Asessment Of Opioid Use In Urban And Rural Contexts, Keith Chichester

All ETDs from UAB

Background: Elements of the physical environment have been shown to influence health behaviors including drug use and overdose mortality. Throughout the opioid epidemic in the United States, rural regions have been disproportionately affected by opioid overdose. Although the relationship between the urban built environment and opioid overdose has been established, little is known as to how trends may differ in rural areas. Methods: Risk terrain modeling was used as a spatial analytical approach to assess environmental features that significantly increase the risk of opioid overdose in Jefferson County, Alabama. Spatial risk assessments were conducted for urban and rural regions as …

Go to article

The Strategy Of Federally Qualified Health Centers: The Influence Of Context And Performance Implications, Seongwon Choi Jan 2019

The Strategy Of Federally Qualified Health Centers: The Influence Of Context And Performance Implications, Seongwon Choi

All ETDs from UAB

The three papers included in this dissertation attempt to provide empirical evidence on the relationship among strategies employed by Federally Qualified Health Centers (FQHCs), the contextual factors and consequent performance. The findings of these studies contribute to the existing body of literature on FQHC strategies and performance. In addition, the findings also provide key practical implications to FQHC managers as well as policymakers. Overall, the results of this dissertation suggest that the FQHC strategy on spatial differentiation is associated with a set of organizational and environmental factors. However, there was little support for the relationship between Medicaid expansion and FQHC …

Go to article

Dna Template Sequence Effects On Rna Polymerase I Transcription Elongation, Andrew Martin Clarke Jan 2019

Dna Template Sequence Effects On Rna Polymerase I Transcription Elongation, Andrew Martin Clarke

All ETDs from UAB

The production of ribosomes represents the major synthetic effort of a rapidly dividing cell, and is intimately linked to the regulation of cell growth and proliferation. Developing a greater understanding of the mechanisms that regulate ribosome biogenesis is therefore crucial to understanding cellular control of the growth cycle. Ribosome biogenesis begins with the synthesis of the 35S ribosomal RNA (rRNA) by RNA polymerase I (Pol I). This RNA is co- and post-transcriptionally processed to produce the 18S, 5.8S, and 25S rRNAs. These RNAs are critical components of ribosomes, and Pol I has been demonstrated to be a key regulation target …

Go to article

Effects Of A Ketogenic Diet On Body Composition, Metabolic Health, And Quality Of Life In Ovarian And Endometrial Cancer Patients, Caroline Whitney Cohen Jan 2019

Effects Of A Ketogenic Diet On Body Composition, Metabolic Health, And Quality Of Life In Ovarian And Endometrial Cancer Patients, Caroline Whitney Cohen

All ETDs from UAB

Ketogenic diets (KDs) have garnered considerable research attention in recent years, having been investigated as a therapy for neurologic, metabolic, and even dermatologic diseases. Recent research has also focused on KDs as a potential intervention for cancer, with preclinical studies demonstrating profound effects such as inhibiting tumor growth, enhancing the effects of radiation and chemotherapy, and prolonging survival. However, to date few studies have been conducted in cancer patients. In order to determine if KDs might augment existing cancer treatment protocols, additional research is needed. Accordingly, the objective of this project was to conduct the first randomized, controlled trial examining …

Go to article

Quality Of Life And Mental Health After Pediatric Central Nervous System Tumor Treated With Surgery Only, Alexandra Cutillo Jan 2019

Quality Of Life And Mental Health After Pediatric Central Nervous System Tumor Treated With Surgery Only, Alexandra Cutillo

All ETDs from UAB

Benign pediatric central nervous system (CNS) tumors treated with surgery alone have been considered relatively harmless to long-term health. However, a developing line of research has identified several late effects experienced in this population including psychological, adaptive, behavioral, neurological, and cognitive problems. Quality of life of children after resection alone has not previously been evaluated, especially in comparison to that of healthy children and children with chronic illness. Further, there has been no research geared toward developing psychosocial programs to address the late effects identified in this population. The following manuscripts contribute to the literature by evaluating and providing potential …

Go to article

Exposure Assessment Of Ultrafine Particles And Hazardous Chemicals In Electronic Cigarettes, Oluwabunmi Magret Dada Jan 2019

Exposure Assessment Of Ultrafine Particles And Hazardous Chemicals In Electronic Cigarettes, Oluwabunmi Magret Dada

All ETDs from UAB

The widespread use of electronic cigarettes (e-cig) among youths and adolescents is a growing public health problem due to exposures to harmful byproducts formed during heating. These byproducts include particulate matter, benzene, and toluene. However, the mechanisms and variables governing their formation including the chemical content of e-cig liquid (e-liquid) are not fully understood. This study aimed to assess exposures to particulate matter, benzene, and toluene in e-cig vapors (e-vapors) and their coupling to e-liquid chemical content. A novel nuclear magnetic resonance spectroscopy method was developed to characterize e-liquids (propylene glycol, glycerol, and nicotine) and the functional content of flavorings. …

Go to article

Surface Treatment Effects On Shear Bond Strength And Biaxial Flexural Strength Of Three Generations Of Zirconia, Yasko A. Darkoue Jan 2019

Surface Treatment Effects On Shear Bond Strength And Biaxial Flexural Strength Of Three Generations Of Zirconia, Yasko A. Darkoue

All ETDs from UAB

SURFACE TREATMENT EFFECTS ON SHEAR BOND STRENGTH AND BIAXIAL FLEXURAL STRENGTH OF THREE GENERATIONS OF ZIRCONIA YASKO A. DARKOUE MASTER OF SCIENCE IN DENTISTRY ABSTRACT Objectives: Mechanical and chemical surface treatments are required to achieve a durable bond to zirconia. The objective of this study is to compare the effects of particle abrasion and pressure on shear bond strength and biaxial flexural strength of Lava (Frame, Plus and Esthetic) zirconia to obtain a favorable combination of pressure and particle type to produce optimum strength and optimize the bond produced. A protocol for mechanical treatment balancing strength of the type zirconia …

Go to article

A Study Of Enamel Thickness Of Permanent Maxillary Canines, Daniel Diaz Rubayo Jan 2019

A Study Of Enamel Thickness Of Permanent Maxillary Canines, Daniel Diaz Rubayo

All ETDs from UAB

Introduction: Tooth agenesis is defined as the lack of development of a tooth. Maxillary lateral incisors have been reported to be missing in 2.2% of the population in the United States of America. Two treatment options are available: opening the space to restore the missing tooth with a dental prosthesis; or close the space by moving the adjacent teeth into the space and substituting the missing lateral incisor with the maxillary canine. With a wider crown and a more convex labial surface than lateral incisors, canines require a significant amount of reduction in order to achieve an adequate occlusion and …

Go to article

Regulation Of St6gal-I In Cancer: Sox2 Identified As Novel Driver Of St6gal-I Expression, Kaitlyn Alexandra Dorsett Jan 2019

Regulation Of St6gal-I In Cancer: Sox2 Identified As Novel Driver Of St6gal-I Expression, Kaitlyn Alexandra Dorsett

All ETDs from UAB

ST6Gal-I is a sialyltransferase that functions to add an 2-6 linked sialic acid to N-linked glycoproteins. The expression of ST6Gal-I is upregulated in many cancers at both the mRNA and protein levels. ST6Gal-I has also been shown to promote cancer stem cell (CSC) characteristics including chemoresistance, tumor-initiating potential, and spheroid growth. However, the transcriptional drivers of ST6Gal-I expression in stem-like cells remain largely unknown. Herein we highlight that SOX2 and ST6GAL1 are both located on one of the most commonly amplified chromosomal segments in cancer, amplicon 3q26. Copy number gains in both SOX2 and ST6GAL1 are observed in roughly 25% …

Go to article

What Are The Factors Related To The Success Or Failure Of Adolescents Enrolled In Uab Tasc Adolescent Substance Abuse Program?, Tamesha Alicia Duesbury Jan 2019

What Are The Factors Related To The Success Or Failure Of Adolescents Enrolled In Uab Tasc Adolescent Substance Abuse Program?, Tamesha Alicia Duesbury

All ETDs from UAB

Illicit drug use during adolescence is common. According to the National Survey on Drug Use and Health, marijuana usage and the misuse of prescription pain relievers were the main substances used during 2016. The survey reported that 4 million people age 12 and over were diagnosed with a marijuana disorder, 2.1 million an opioid use disorder, and 1.8 million with a prescription pain reliever disorder. Limited research has been conducted on adolescent substance abuse programs, yet there is a need for effective and efficient interventions. Using multiple logistic regression this study sought to identify the factors contributing to the success …

Go to article

Regulation Of Intestinal Innate Lymphoid Cells In Acute And Chronic Inflammation, Sarah Dulson Jan 2019

Regulation Of Intestinal Innate Lymphoid Cells In Acute And Chronic Inflammation, Sarah Dulson

All ETDs from UAB

The Innate Lymphoid Cell (ILC) population encompasses five subpopulations that are increasingly appreciated to participate in immune responses to inflammation and injury as well as directly influence homeostasis in tissues throughout the body. ILCs are enriched at mucosal surfaces, such as the gastrointestinal tract, where they are transcriptionally poised for rapid activation. Therefore, ILCs contribute significantly to protective responses to infection, and can exacerbate inflammation and disease when dysregulated. Herein, we demonstrate two pathways that regulate intestinal ILC phenotype and function and delineate the impact of these pathways on both protective and pathogenic roles of ILCs. Using a murine model …

Go to article

Impact Of Familial Chronic Illness On Adolescent Somatization, Lindsey Elliott Jan 2019

Impact Of Familial Chronic Illness On Adolescent Somatization, Lindsey Elliott

All ETDs from UAB

Somatic symptoms, or physical symptoms that do not have an identifiable organic etiology, have a prevalence of 10-30% in children. They have been associated with poor psychosocial outcomes in children, including emotional and behavioral problems, school absences, and impaired social functioning. Further, these symptoms represent a burden on the health care system as patients with somatic symptoms are frequent users of both primary care physicians and specialists. The etiology of somatic symptoms is thought to be due to a combination of biological, psychological, interpersonal, and healthcare factors. Two theories exist regarding the etiology of somatic symptoms. Brown’s integrative conceptual model …

Go to article

Marcks Effector Domain: Functions In Glioblastoma Progression And Novel Cytolytic Therapy, Nicholas James Eustace Jan 2019

Marcks Effector Domain: Functions In Glioblastoma Progression And Novel Cytolytic Therapy, Nicholas James Eustace

All ETDs from UAB

Glioblastoma (GBM; grade IV astrocytoma) is the most common primary adult brain malignancy and remains incurable despite tremendous advances in our understanding of this heterogeneous disease. In this dissertation, we explore the challenges encountered in the treatment of GBM and discuss a promising new therapeutic approach gleaned from studies of the phospholipid binding “effector” domain (ED) of the protein Myristoylated alanine-rich protein C kinase substrate (MARCKS). Following an introduction to central nervous system (CNS) tumors and the grading of diffuse gliomas, we explain how recent advancements to our understanding of the cellular and molecular composition of CNS tu-mors, and the …

Go to article

The Relationship Of Bedside Assessment Of Orientation And Cognition To Treatment Outcome In Moderate To Severe Traumatic Brain Injury: A Growth Curve Analysis, Amber Marie Fahey Jan 2019

The Relationship Of Bedside Assessment Of Orientation And Cognition To Treatment Outcome In Moderate To Severe Traumatic Brain Injury: A Growth Curve Analysis, Amber Marie Fahey

All ETDs from UAB

Disorientation and cognitive impairment are commonly experienced in acute moderate to severe TBI patients and deficits early in recovery are predictive of worse long-term outcome. Hence, tracking recovery over time is a significant aspect of rehabilitation research. The Orientation-Log (O-log) and Cognition-Log (Cog-log) are important clinical measures used to monitor cognitive progress during treatment and previous research has shown them to be predictive of long-term outcome. This study used two-level growth curve modeling to, 1) determine the growth trajectory of orientation and cognition in persons with moderate to severe TBI in acute rehabilitation, as determined by the O-log and Cog-log, …

Go to article

Wear Of Orthodontic Bite Turbos And Opposing Enamel, Kyle Feagin Jan 2019

Wear Of Orthodontic Bite Turbos And Opposing Enamel, Kyle Feagin

All ETDs from UAB

Orthodontic bite turbos are used to separate the maxillary and mandibular arches when disocclusion is needed for facial placement of orthodontic brackets or extrusion of teeth. The bite turbo should have adequate wear resistance to maintain the disocclusion but also avoid abrasion of the opposing enamel. The objective of this study was to measure the wear and opposing enamel wear of three materials used as bite turbos. 8 specimens (10x8x4 mm) each of Transbond LR (3M), Transbond Plus (3M) and Triad gel (Dentsply) were prepared in silicone molds and light cured for 30 seconds using an Acteon Satelec Blue Ray …

Go to article

Bet Bromodomain Inhibition As An Approach For Treatment Of Cholangiocarcinoma, Samuel Charles Fehling Jan 2019

Bet Bromodomain Inhibition As An Approach For Treatment Of Cholangiocarcinoma, Samuel Charles Fehling

All ETDs from UAB

Cholangiocarcinoma (CCA) is a highly aggressive neoplasm which arises from the epithelial layer of the biliary tract. It is the second most common primary hepatic malignancy. As CCA is typically diagnosed at late disease stage, the current standard of care, resection followed by gemcitabine with cisplatin, is not effective. Further, up to 90% of CCA patients are ineligible for resection. Of those eligible for resection, postoperative chemotherapy does not prolong overall survival leading to a 5-year survival of ~30%. Previously, mutations have been identified in KRAS (17% of CCA cases), TP53 (44%) and SMAD4 (17%) but none have been recognized …

Go to article

Utilization Of The Zebrafish Model System To Predict Effects Of Dietary Lipid Composition On Human Health, Lauren Adele Fowler Jan 2019

Utilization Of The Zebrafish Model System To Predict Effects Of Dietary Lipid Composition On Human Health, Lauren Adele Fowler

All ETDs from UAB

Obesity is a disease that encompasses the interaction of both genetics and life-style factors, and the pathology behind its development remains unclear. Specifically, defining the influence of dietary lipid intake on adiposity and metabolic health continues to be a fundamental challenge, and the use of animal models will be required to gain a full understanding of the processes contributing to diet-induced obesity in humans. The zebrafish Danio rerio has emerged as a powerful model system to study diet-induced obesity and metabolic disease in humans, while simultaneously offering multiple advantages over rodent models. This dissertation addresses multiple aspects regarding the use …

Go to article

Associations Between Dietary Fat Intake And Waist Circumference, Phonchit Teng Soukhamneut Jan 2019

Associations Between Dietary Fat Intake And Waist Circumference, Phonchit Teng Soukhamneut

All ETDs from UAB

The objective of this study was to assess: 1) trends in dietary fat intake from 2003-2016 2) the association between type of dietary fat intake and waist circumference (WC), 3) the association between type of dietary fat intake and body shape, and 4) whether these associations vary by sex and race/ethnicity. This secondary data analysis included 27,057 adults aged 19 to 65 from the National Health and Examination Survey (NHANES) 2003-2016. For WC, participants were categorized into high-risk (men: WC ≥ 40 in; women: WC ≥ 35 in) and low-risk (men: WC < 40 in; women: WC < 35 in). Total fat intake was categorized as high (TOTFAT ≥ 35%) and low (TOTFAT< 35%). Saturated fat intake was categorized into high (SATFAT ≥ 10%) and low (SATFAT < 10%). Unsaturated fat intake was categorized into high (UNSATFAT ≥ 25%) and low (UNSATFAT < 25%). Logistic regression was performed to assess the associations between DFI and WC and DFI and body shape, controlling for age, BMI, and total caloric intake. NHW men with high TOTFAT were found to have 1.41 (OR: 1.41, 1.19 – 1.68) times the odds of having a high-risk WC compared to men with a diet low in TOTFAT, controlling for age, BMI, and total caloric intake. NHW men with a diet high in SATFAT were at increased odds of having a high-risk WC compared to men with a diet low in SATFAT, after controlling for covariates (OR: 1.49, 1.21 -1.84). NHW men with a diet high in UNSATFAT were at increased odds of having a high-risk WC compared to men with a diet low in UNSATFAT after controlling for covariates (OR: 1.375, 1.09 – 1.74). There were no significant associations found among NWB and MA men for any type of dietary fat intake. For women, no associations were found between type of dietary fat and WC by race/ethnicity. There were no associations between DFI and body shape by race/ethnicity groups and sex. Future studies are needed to further investigate the body shape cut-off points for increased risk associated with chronic disease.

Go to article

Characterization Of Chemical Uptake And Aryl Hydrocarbon Receptor Mutations In Zebrafish, Jaclyn Paige Souder Jan 2019

Characterization Of Chemical Uptake And Aryl Hydrocarbon Receptor Mutations In Zebrafish, Jaclyn Paige Souder

All ETDs from UAB

In a society driven by technology and industry, we must be increasingly aware of how changes to our environment impact our health. This is especially true concerning embryonic development, which is easily influenced by extra-embryonic factors, including environmental contaminants. Determining how exogenous compounds are absorbed, which receptors they act through, and how these receptors act endogenously is important to fully understand to what extent developmental exposures impact fetal and adult health. I have used the zebrafish model system to address these questions for two classes of environmentally-relevant chemicals—estrogens and dioxins. First, I developed an assay to measure the uptake of …

Go to article

The Role Of Protein Synthesis Attenuation And Eif2-Alpha Phosphorylation In Retinal Degeneration, Christopher Ryan Starr Jan 2019

The Role Of Protein Synthesis Attenuation And Eif2-Alpha Phosphorylation In Retinal Degeneration, Christopher Ryan Starr

All ETDs from UAB

Inherited retinal degeneration is a class of diseases in which there is no cure and very few treatment options available. An activated unfolded protein response has been detected in various animal models of retinal degenerative diseases. Several groups have found heightened activation of one pathway of the unfolded protein response in particular, the protein kinase R-like endoplasmic reticulum kinase signaling cascade, which converges on and phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 to transiently halt protein synthesis and allow the cell to reestablish homeostasis. Although it is widely accepted that this signaling is inherently protective, hyperactivity or …

Go to article

Dysregulation In The Central Nervous System Upon Mcmv Infection In Newborn Mice, Cathy Yea Won Sung Jan 2019

Dysregulation In The Central Nervous System Upon Mcmv Infection In Newborn Mice, Cathy Yea Won Sung

All ETDs from UAB

Human cytomegalovirus (HCMV) infection is a major cause of morbidity in infants and children throughout the world. Between 0.2-1.2% of all live births is infected with HCMV in the United States. Approximately 5-15% of these newborn babies will develop long-term neurological damage resulting in motor disorders, mental retardation, and sensorineural hearing loss. Although the neurological sequelae associated with congenital HCMV infections are well characterized, little is known about the pathogenesis of the damage to the central nervous system (CNS). To study the pathogenesis of congenital HCMV infection, we have developed a mouse model in which newborn mice are infected intraperitoneally …

Go to article

Unintentional Childhood Injuries In Rural Uganda: The Role Of Sibling Supervision And The Potential For Behavior Change Through Classroom-Based Instruction, Marissa Swanson Jan 2019

Unintentional Childhood Injuries In Rural Uganda: The Role Of Sibling Supervision And The Potential For Behavior Change Through Classroom-Based Instruction, Marissa Swanson

All ETDs from UAB

Objective: Unintentional childhood injury is a significant global health burden particularly in low and middle income countries (LMIC). Effective supervision can reduce risk of injury to supervisees. Frequently, older siblings assist in supervising younger siblings, but may not be as effective as adult caregivers at preventing supervisee injury. The current investigation had three primary objectives: 1) Assess Ugandan adult caregivers’ self-reported expectations for children to provide sibling supervision; 2) Assess sixth-grade students’ self-reported experiences providing supervision; 3) Determine whether students’ supervision knowledge and skill improve through participation in the Super Siblings program, a novel classroom-based, culturally-adapted intervention. Methods: Adult caregivers …

Go to article

Drive-By Bridge Monitoring And Damage Detection, Chengjun Tan Jan 2019

Drive-By Bridge Monitoring And Damage Detection, Chengjun Tan

All ETDs from UAB

Bridges are key components of the transportation network, and their safety is essential to maintain effective and safe operation of the transportation facilities. To maintain the structural integrity of the bridges, it is essential to estimate the extent and location of the structural damage through periodic monitoring. Therefore, there is considerable interest in bridge damage detection and considerable progress has been made in recent years. The traditional bridge health monitoring requires many sensors installed on the bridge to collect vibration data for damage assessment, which is expensive, time-consuming, and even dangerous in-site. Compared with traditional ways, the concept of indirect …

Go to article

First Prev Next Last