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Cytotoxic Activity Of Stem Of Pycnarrhena Cauliflora Through Apoptosis Induction On Human Breast Cancer Cell Line T47d, Masriani, Rudiyansyah, Rini Muharini, Eny Enawaty

Pharmaceutical Sciences and Research

Cytotoxic activities of extracts of Pycnarrhena cauliflora leaves, stems and roots on some human cancer cells have been known. However, the cytotoxicity of stem of Pycnarrhena cauliflora on human breast cancer cell line T47D through an apoptosis induction has not been proven yet. This study was an effort in understanding the cytotoxic activity of stem of Pycnarrhena cauliflora through apoptosis induction. The crude ethanol extract was partitioned between n-hexane and dichloromethane at pH 3, 7 and 9, which was subsequently tested for their cytotoxic activity against human breast cancer cell line T47D by using 3-(4,5-dimethylthiazol-2-yl)- 2,5-diphenyltetrazolium bromide (MTT). Flow cytometric …

Efek Xilooligosakarida (Xos) Dalam Mencegah Diabetes Mellitus Tipe 2, Lusi Putri Dwita, Hanifah Rahmi

Pharmaceutical Sciences and Research

Type 2 diabetes mellitus (T2DM) is one of the leading causes of death in Indonesia. Early intervention is very important to delay the development of this disease. This study aimed to determine the effect of XOS (Xylo-oligosaccharide) as prebiotic in preventing insulin resistance. The rats were divided into 5 groups: XOS 2 gr/kg, XOS 1 gr/kg, XOS 0.5 gr/kg, diabetic control, and non-diabetic control. Animals were given the test substances and standard feed for 2 weeks then induced with STZ (streptozotocin) except for non-diabetic control. On the 19th day, the data was collected. The results showed that XOS 2 gr/kg …

Bpc 157 Promotes Skeletal Muscle Cells Migration In Association With Up-Regulation Of Paxillin And Vinculin Expression, Szu-Heng Wang, Li-Ping Lin, Miao-Sui Lin, Jong-Hwei S. Pang, Wen-Chung Tsai

Rehabilitation Practice and Science

BPC 157 was first isolated from human gastric juice. It is a stable 15-amino acid fragment (GEPPPGKPADDAGLV), and the healing-promoting effects of BPC 157 have been reported on muscle injury. The aim of this study was to investigate the effect and molecular mechanism of BPC 157 on migration of skeletal muscle cells. Skeletal muscle cells were isolated from the gastrocnemius muscle of Sprague-Dawley rats, and treated with BPC 157. The cell migration was evaluated by transwell filter migration assay. The spreading of cells was evaluated microscopically. The protein expressions of paxillin and vinculin (which were positive regulators of cell migration) …

Management And Population Status Of Kihansi Spray Toad Nectophrynoides Asperginis In Captive Breeding Facilities In Tanzania, Cuthbert L. Nahonyo, Ezekiel M. Goboro, Richard S. Ugomba, Emmanuel S. Nkombe, Severinus Mutagwaba, Hussein Adam, Juma I. Kimera, Person Kalenga, Wilirk Ngalason

Tanzania Journal of Science

Kihansi spray toad Nectophrynoides asperginis was discovered in 1996 in Kihansi gorge. The toad was declared extinct in the wild in 2009 due to habitat alteration. Before its extinction, 499 individuals were flown to the United States of America zoos in 2000 for captive breeding. In 2010, the University of Dar es Salaam, and in 2011 the Kihansi captive breeding facilities were established in Tanzania. The intention was to breed, and reintroduce the toad back to the natural environment in the gorge. The founder populations for the two facilities were sourced from the USA zoos. This study addresses captive management …

Some Histopathological Findings In Dead Kihansi Spray Toads In Captivity, Joshua J Malago

Tanzania Journal of Science

Raising of Kihansi spray toad (KST), Nectophrynoides asperginis, in captivity is associated with disorders that can be fatal. Since diagnosis of these disorders cannot be confirmed grossly, the current study was aimed at exploring histopathological findings in dead KSTs kept under captivity in Tanzania. Dead KSTs were immediately recovered, observed for gross changes, fixed in 10% neutral buffered formalin, processed routinely, and stained sections reviewed for histological changes. Observed infectious agents were strongyloides (25.3%), ciliates (1.7%), lungworms (0.6%), fungi (3.4%) and bacteria (5.1%) or mixed infections (9%) of these agents. Noted histopathological lesions in affected organs included infiltration of inflammatory …

Understorey Bird Communities 8 And 18 Years After River Diversion In Kihansi Gorge, Udzungwa Mountains In The Eastern Arc Mountains, Tanzania, Chacha Werema, Charles A. Msuya

Tanzania Journal of Science

On the most south-western slopes of the Udzungwa Mountains in Tanzania lies Kihansi River. The river was diverted underground in 2000 to run electric turbines for electricity generation. Using mist netting, pre-diversion (in 1998 and 1999) and short term post-diversion (in 2001) effects of the river diversion on understorey birds were undertaken before and year after river diversion, respectively. Intermediate and long-term effects of river diversion on understorey birds at the same transects are non-existent. In September 2008 and August and September 2018, using mist nets, birds were surveyed at the same transects  to assess whether or not there have …

Mammals Inventory Of The Kihansi River Gorge In Udzungwa Mountains, Tanzania, Dennis K. Ikanda, Samuel N. Mtoka, Mustafa Hassanali, Anna Mshanga

Tanzania Journal of Science

The Kihansi gorge montane forest in Udzungwa Mountains forms part of the Eastern Arc Mountains (EAM) which contain some of the most biologically diverse and endemic montane ecosystems in all of Africa. The Kihansi river gorge was opened up for hydroelectric development in the late 1990s, attracting hundreds of farming communities whose activities lead to environmental degradation and hence presumed biodiversity loss in the montane forest which is not understood. Using camera traps, an inventory of mammals of the area was conducted for 24 consecutive days. About 14 mammal species were photo captured, indicating diverse assemblage of large and medium …

Histopathological Diagnosis Of Diseases Affecting Amphibians Inhabiting Kihansi Gorge, Tanzania, Joshua J Malago

Tanzania Journal of Science

Kihansi gorge is a natural habitat to Kihansi spray toad (KST), Nectophrynoides asperginis. The toad is extinct in its natural habitat partly due to diseases. Efforts to successfully re-introduce it are primed by awareness and mitigation of prevalent diseases at the gorge. This study aimed at exploring the prevalent amphibian diseases at and around Kihansi gorge. A total of 182 individuals from Petropedetes yakusini (n = 60), Nectophrynoides tornieri (n = 60) and Leptopelis uluguruensis (n = 62) species were collected, humanely sacrificed, fixed in formalin, routinely processed, sectioned, stained with haematoxylin and eosin and analysed for diseases by histopathology. …

Full Issue, Iajbs Ateneo De Manila University

Journal of Management for Global Sustainability

No abstract provided.

Correlation Of Population And Environmental Behavior With Rat Density Rate In Plague Disease-Focus, Threatened And Safe Areas In Tutur District, Pasuruan Regency, 2016, Evi Noerista Lestari, Susilowati Andajani, Usman Hadi

Folia Medica Indonesiana

Plague disease remains a public health problem in the world. According to the International Health Regulations (IHR), an outbreak is an infectious disease that has the potential to cause an outbreak. The purpose of this study was to analyze a significant relationship between human behavior and the environment with the density of the number of rats in the focus, threatened and outbreak-safe areas in Tutur Regency, Pasuruan Regency, in 2016. This was an observational analytic study with cross correlation sectional where the research variables are population behavior, environment, and the number of rat densities observed once at a time. The …

The Effect Of Subconjunctival Bevacizumab On Angiogenesis In Rabbit Model, Nurwasis Nurwasis, Diana Yuliawati, Evelyn Komaratih, Heriyawati Heriyawati

Folia Medica Indonesiana

Bone is an important organ for supports the body that stores reserve of calcium, phosphorus, and other minerals. In fracture conditions where bleeding, soft tissue edema, nerve damage, and blood vessels around the bone damage happen, they can cause the mobilization of these minerals in the surrounding tissue. One of the efforts made in the treatment of these fractures is reconnection, in which it works by filling of bone defect with a matrix and administration of anti-infection. Biomaterial filling in defective bone is thought to accelerate the healing process of bone fracture and prevent osteomyelitis. For this reason, this study …

A Framework For The Development Of A Global Standardised Marine Taxon Reference Image Database (Smartar-Id) To Support Image-Based Analyses, Kerry L. Howell, Jaime S. Davies, A. Louise Allcock, Andreia Braga-Henriques, Pal Buhl-Mortensen, Marina Carreiro-Silva, Carlos Dominguez-Carrió, Jennifer M. Durden, Nicola L. Foster, Chloe A. Game, Becky Hitchin, Tammy Horton, Brett Hosking, Daniel O.B. Jones, Christopher Mah, Marchais C Laguionie, Lenaick Menot, Telmo Morato, Tabitha R.R. Pearman, Nils Piechaud, Rebecca E. Ross, Henry A. Ruhl, Hanieh Saeedi, Paris V. Stefanoudis, Gerald H. Taranto, Michael B. Thompson, James R. Taylor, Paul Tyler, Johanne Vad, Lissette Victorero, Rui P. Vieira, Lucy C. Woodall, Joana R. Xavier, Daniel Wagner

School of Biological and Marine Sciences

No abstract provided.

Characteristics Of Habitat, Distribution, And Diversity Of Anopheles Spp In Kemelak Bindung Langit Village, Ogan Komering Ulu Regency, South Sumatra, Giri Maretasari, Yuanita Windusari, Syafrina Lamin, Laila Hanum, Dwi Septiawati

Journal of Environmental Science and Sustainable Development

Malaria is an infectious disease caused by Plasmodium andis transmitted through the bite of a female Anopheles vector. Ogan Komering Ulu (OKU) is a district in South Sumatra that is endemic to malaria. The study aims to determine habitat type, environmental factors that influence larvae development, and distribution of Anopheles larvae. The experiment was conducted from January to February 2019 in the Kelurahan Kemelak Bindung Langit, OKU. Species identification was carried out in the Entomology Laboratory, Baturaja Health Research and Development Center, OKU. Sampling locations were determined based on field observations, through simple purposive sampling. Identification of mosquito larvae which …

Relationship Between Sustainable Outer Space Law And The Use Of Satellite Technology In Handling Marine Plastic Debris, Andreas Pramudianto

Journal of Environmental Science and Sustainable Development

Since the discovery of plastic material, which ends up as plastic waste after use and partly enters the sea, it has become a global problem that needs serious treatment. No international agreement exists about handling marine plastic debris. By contrast, national laws have been created to plastic bags and plastic debris. Currently, the existing legal instruments, especially in outer space law, are still traditional and inadequate. A sustainable new paradigm in outer space law is needed, such as the use of satellite technology, such as the COSMOS satellite by RKA Recosmos, for global environmental issues, including the ozone layer, climate …

Predictive Modeling Of Influenza In New England Using A Recurrent Deep Neural Network, Alfred Amendolara

Theses

Predicting seasonal variation in influenza epidemics is an ongoing challenge. To better predict seasonal influenza and provide early warning of pandemics, a novel approach to Influenza-Like-Illness (ILI) prediction was developed. This approach combined a deep neural network with ILI, climate, and population data. A predictive model was created using a deep neural network based on TensorFlow 2.0 Beta. The model used Long-Short Term Memory (LSTM) nodes. Data was collected from the Center for Disease Control, the National Center for Environmental Information (NCEI) and the United States Census Bureau. These parameters were temperature, precipitation, wind speed, population size, vaccination rate and …

Dental Professionals Occupational Noise Exposure And Its Auditory And Non-Auditory Effects, Alexis Frees

Theses

The purpose of this study was to assess noise exposure and its auditory and non-auditory effects on workers in five clinical departments in the School of Dental Medicine at Rutgers Biomedical Health Sciences Campus in Newark, New Jersey. The study included environmental noise level measurement, dental instrument sound level measurement, personal noise dosimetry and a questionnaire survey to assess non-auditory effects. Octave band analysis of environmental noise levels showed that they are slightly above the standard noise criteria for clinics, and measurements from six dental instruments confirm that they contribute higher sound pressure levels at the frequencies of 1000, 2000, …

Impact Of Stirrer Speed And Media Type-Loading On The Breakage Kinetics During Wet Stirred Media Milling Of Griseofulvin, Nathaniel Parker

Theses

The aim of this study is to investigate the impact of stirrer speed (2000-4000 rpm) and bead loading (~20-60%) on the breakage kinetics-energy consumption during milling of griseofulvin, a poorly soluble drug, and compare the performance of crosslinked polystyrene (CPS) beads with that of yttrium-stabilized zirconia (YSZ) beads. Laser diffraction, SEM, viscometry, and XRPD were used for characterization. A microhydrodynamic model was used to interpret the breakage kinetics. An increase in stirrer speed led to faster breakage due to more frequent and forceful CPS bead-bead collisions. Despite causing slight decrease in maximum contact pressure, an increase in CPS bead loading …

Lithium As A Possible Therapeutic Drug In Posttraumatic Brain Injury, Tulika Das

Theses

Lithium, a popular drug for treating mental health disorder has shown promising effect in recent research on traumatic brain injury (TBI). The mechanism of lithium for treating bipolar mood disorder is still not properly understood, but recent studies showed that lithium is neuroprotective in TBI. In my thesis, the neuroprotective effects of lithium were examined in primary neuronal culture and mild blunt injury using rodent model of Lateral Fluid Percussion Injury (LFPI). At first determination of the neuroprotective/toxicity effects of lithium in neuronal culture was done and observed that 0.5 - 1.0 mM concentrations were found to be neuroprotective as …

Opportunities For Improving Livestock Production With E-Management Systems, Dave L. Swain, Rebecca N. Handcock, Greg J. Bishop-Hurley, Don Menzies

IGC Proceedings (1977-2023)

There is increased interest in hardware and software that can support e-Management for grassland-based livestock industries. Managers of grazing livestock were early adopters of radio frequency identification (RFID) technologies automatically monitoring individual animal performance. Recent developments of remote sensing, automated individual recording and management, location based systems, improved data transfer and technologies that can be used in more extensive grazing systems are providing new opportunities for the development of e-Management systems. There is a need for better data integration and systems that can provide the best available information to enable better decision-making. For greater industry adoption of more integrated e-Management …

Growth Of Bali Bulls Fattened With Forage Tree Legumes In Eastern Indonesia: Leucaena Leucocephala In Sumbawa, Tanda Panjaitan, Muhammad Fauzan, H. Dahlanuddin, Michael J. Halliday, H. Max Shelton

IGC Proceedings (1977-2023)

The contribution of West Nusa Tenggara Province to domestic beef supply in Indonesia is relatively small, however, beef cattle are very important for the livelihoods of smallholder farmers in the region.

Bali cattle (Boss javanicus) are the predominant breed as they are adapted to harsh nutritional conditions, are highly fertile and have low calf mortality (Toelihere 2003). While genetically capable of achieving a growth rate of 0.85 kg/d (Mastika 2003), Panjaitan (2012) identified poor nutrition as a severe limitation to animal growth in traditional village systems. Improving feed quality and supply is vital to increasing growth rates and …

Effect Of High Se And Co Alfalfa Forage On Animal Production, Xiao-Lei Jie, Xiao Guo, Hua-Feng Hu

IGC Proceedings (1977-2023)

Total and available selenium (Se) and cobalt (Co) concentrations are low in Chinese soils, especially those found in mainly in temperate humid sub-humid conditions in the northeast to the southwest band across China (Tan et al. 2002). The levels of Se and Co are marginally deficit in the brown soil of the Yellow River region which causes lower production level and quality in forage and crop plants. Application of Se and Co fertilizers to arable lands is essential to produce high Se and Co forages. Henan is a Province where produce high-quality grass forages are used to support dairy …

Performance, Carcass Characteristics And Meat Quality Of Grazing Lambs Finished On Tropical Grasses, Cesar H. E. C. Poli, Samuel Carnesella, Fernando M. Souza, Concepta Mcmanus, Zélia M. S. Castilhos, Liris Kindlein, Jaime U. Tarouco

IGC Proceedings (1977-2023)

Brazil is a country of continental size, and more than seven million ha are occupied with tropical pasture. Worldwide animal production from tropical pastures is also very significant where Cynodon, Panicum and Paspalum are important genus. These grasses are widely used in the production of cattle, and are growing in importance for sheep production, but their potential for producing quality lamb is not fully known.

The objective of this study was to evaluate the potential of two tropical grasses for finishing lambs in autumn to reduce the seasonality of production of lamb for meat.

Alternative Pasture Development System And Breeding Weight For Beef Heifers, H. A. Lardner, Daalkhaijav Damiran, Steve Hendrick, Kathy Larson

IGC Proceedings (1977-2023)

Proper development of replacement beef heifers is critical and needs to be accomplished at lower costs without sacrificing reproductive performance. The current recommendations indicate heifers should reach approximately 65% of mature body weight (MBW) at breeding for successful reproduction (Patterson et al. 1992; NRC 1996). Meeting heifer maintenance and gestation nutrient requirements are getting more economically challenged for beef producers in western Canada. Therefore, producers are moving from drylot development systems where cattle are housed and fed in pens to the adoption of extensive grazing systems (Kelln et al. 2011) in field paddocks. Limited research has been conducted …

Variation Of Rumen Bacterial Diversity In Steers After The Beginning Of Grazing, Miwa Nakano, Satoshi Haga, Masanori Tohno, Kazuhiro Matoba, Ryuichi Uegaki, Hiroshi Ishizaki

IGC Proceedings (1977-2023)

Holstein heifers before or after puberty often are herded on public pastures in Japan. The herbage intake and rumen fermentation of grazing heifers that are not adapted for fresh herbage decreases due to a change of feed from stall-fed dried forage to fresh herbage. This limits their performance during the first several weeks on pasture. Thus, the feeding program such as supplementation before and after the beginning of grazing is important. An increase in ammonia concentration and a decline in fibre degradation in the rumen of a heifer (both of which occur simultaneously with low herbage intake and rumen fermentation) …

Forage Systems Effect On Forage-Fed Beef Production, Guillermo Scaglia, Basu Bhandari, Jeffrey M. Gillespie, Jim J. Wang

IGC Proceedings (1977-2023)

Locally produced forage-finished beef offers high value while enhancing economic, environmental, and social sustainability. It enhances environmental quality and the natural resource base, and makes good use of resources both on and off-farm. On the farm, it makes the most of the ability of cattle to convert grass to meat in a low-input system, making efficient use of solar energy, improving soil nutrient cycling, conserving soil and water, and limiting reliance on non-renewable resources (DeRamus 2004). Although the major causes of increased greenhouse gas emissions are due to population growth and industrialization, agriculture contributes to carbon dioxide (CO2) emissions through …

Activity, Physiology And Milk Production Of Yaks And Two Different Yak Crossbreds Grazing Himalayan Pasture Sites At 4700 M And 3000 M, Shanker R. Barsila, Naba R. Devkota, Michael Kreuzer, Svenja Marquardt

IGC Proceedings (1977-2023)

Yaks (Bos grunniens) and crossbreds of yaks with different local cattle breeds are important for the livelihood of local herders in the Himalayas. They are often kept in a system of transhumance comprising the use of different pasture sites for grazing along an altitudinal gradient throughout the year. The animals are moved upwards to the high altitude pastures in spring/early summer and gradually moved downwards in late summer/autumn. Yaks are suitable for very high altitudes as they are especially adapted to low oxygen partial pressure, forage scarcity and cold and harsh environment (Wiener et al. 2003). However, …

Fatty Acid Metabolism On Pasture- And Feedlot-Finished Cattle, Cuk T. Noviandi, Robert E. Ward, Jong-Su Eun, Dale R. Zobell, Rusty D. Stott, Blair L. Waldron, Mike D. Peel

IGC Proceedings (1977-2023)

Feeding high-grain diets to finishing beef cattle results in high proportions of saturated fatty acids (SFA) in the beef, which is considered to confer negative impacts on human health. In contrast, pasture-finished cattle produce lower proportion of SFA, greater n-3 and less n-6 polyunsaturated fatty acids (PUFA), and higher conjugated linoleic acids (CLA) compared to high grain-finished beef (Noviandi et al. 2012). Increased n-3 PUFA, especially C18:3 n-3, can reduce the risk of heart disease, hypertension, inflammation, and mammary cancer, and lower cholesterol concentration in blood (De Deckere et al. 1998; Tapiero et al. 2002).

Nitrogen fertilisation …

Development Of Feeding System Based On Azolla (Azolla Pinnata) And Sheanut Cake (Vitellaria Paradoxa) For Nellore Sheep Reared In Different Production Systems, K. Sarjan Rao, Y. Ravindra Reddy

IGC Proceedings (1977-2023)

Since protein sources such as ground nut cake and soya bean are too expensive to feed as supplements to livestock in India, steps have been taken to reduce cost by utilizing alternative feedstuffs to replace the traditional sources in ration formulation (Parashuramului et al. 2013). Azolla which is a free-floating nitrogen fixing water fern has a potential to be used as a protein supplement for ruminants (Ahirwar and Leela, 2012). Sheanut cake (Vitellaria paradoxa) which is produced after extraction of fats use in cosmetics and as a cocoa butter substitute in chocolate making, is also a rich …

Lca Study On Sheep Milk Production In Sardinian Farms At Different Input Levels, Enrico Vagnoni, Antonello Franca, Leo Breedveld, Claudio Porqueddu, Pierpaolo Duce

IGC Proceedings (1977-2023)

This paper illustrates a Life Cycle Assessment (LCA) study carried out with the purposes of comparing the environmental impacts of sheep milk production from three different dairy farms in Sardinia, Italy, characterized by different production systems.

Forage Allowance And Cow Genotype, Tools To Increase Animal Production In Native Pastures, Pablo Soca, Mariana Carriquiry, Martín Do Carmo

IGC Proceedings (1977-2023)

In eight plots (four per block) the effects of two FA per two cow genotypes were tested from August 2007 to March 2010, on a Campos grassland (major species were Axonopus affinis, Oxalis sp., Cyperus sp., Cynodon dactylon, Eryngium nudicaule, Gaudinia fragilis, Chevreulia sarmentosa, Stipa setigera, Paspalum notatum and Coelorhachis selloana) in Uruguay (32º 20` S, 54º 26` W). Forage allowance varied seasonally, in HIGH (5, 3, 4 and 4 kg DM/kg LW) and LOW (3, 3, 2 and 2 kg DM/kg LW) during autumn, winter, spring and summer; respectively. Continuous stocking method was …