Digital Commons Network^™

Ending My Childhood: Stories Of Growth, Jackson Keller

All NMU Master's Theses

No abstract provided.

Assessment Of Sex Differences And Amphetamine On Schedule-Induced Polydipsia, Min Park

All NMU Master's Theses

Amphetamine (AMPH) is one of the most common psychotropic drugs abused in the United States. Its major pharmacological effect is to increase synaptic dopamine levels in the mesolimbic reward pathway, which in turn causes behavioral effects in animals, and subjective effects in humans. These reinforcing properties of AMPH trigger very strong levels of craving the drug, and eventually result in patterns of compulsive use of AMPH. Regarding psychostimulant action, female rats have been reported to be more vulnerable to the reinforcing effects of psychostimulants. In the current study, schedule-induced polydipsia (SIP), an animal model of compulsive behavior, was applied for …

Animal Assisted Therapy And Support Animals, What Mental Health Professionals Know And Understand, Alexandro H. Velez

UNLV Theses, Dissertations, Professional Papers, and Capstones

Animal-assisted therapy can greatly benefit mental health professionals with clients in and out of the school settings in many ways. It is believed mental health professionals are successfully implementing Animal Assisted Therapy, even though some are not. Mental health professionals who are not using Animal Assisted Therapy are not doing so as the result of various variables, such as lack of information, knowledge, training, certification and policies, which prevents them from using Animals Assisted Therapy with clients and the community. It is also believed some mental health professionals are using animals as part of therapeutic interventions without proper training. The …

Early Changes In Memory, Motor Coordination And Strength In The Transgenic Rat Model Of Alzheimer’S Disease, Tgf344-Ad, Mark Andrew Winslow

Boise State University Theses and Dissertations

Introduction: Alzheimer’s disease (AD) is the most common form of dementia and an estimated 5.7 million American’s are currently suffering from this disease resulting in $277 billion in health care costs as of 2018. As the number of cases and cost are expected to double by 2050, new approaches are needed to properly identify at-risk individuals prior to irreversible changes to the brain caused by this disease. Purpose: Through the use of a novel rodent model, this study assessed early changes in muscular coordination and strength relative to cognitive decline due to AD, as well as providing insight into the …

Seed Predation By Owyhee Harvester Ants And The Potential Of Seed Introductions In Recovery Efforts For Slickspot Peppergrass, Jennifer A. Brown

Boise State University Theses and Dissertations

Slickspot peppergrass (Lepidium papilliferum) is a rare plant endemic to the sagebrush-steppe habitat in southwestern Idaho. Within sagebrush-steppe, the plant is restricted to microsites known as “slick spots”– shallow depressions of soil characterized by distinct clay layers and surface water retention that is higher than that of surrounding areas. Having one of the highest extirpation rates among rare plant taxa in Idaho, and considering its unique habitat requirements, limited range, and declining numbers, land managers and conservationists have voiced concern regarding the species’ long-term viability. While range-wide declines in slickspot peppergrass have been attributed largely to the loss …

Dynamic Modeling Of A Suspended And Shock Isolated System In Seismic Loading, Emilie Murphy

Boise State University Theses and Dissertations

A dynamic model for a suspended and shock isolated system is derived and implemented in MATLAB’s Simulink software. The purpose of this implementation is to create a design tool which is modularized to be able to accommodate any configuration of a similar system in any kind of loading. The design tool is used to compute the level of acceleration experienced at specific points in space within the system in the presence of seismic events, as typified by the dynamic displacement caused by the Sumatra, Indonesia earthquake of 2007. It is determined that under this 8.4 magnitude earthquake, accelerations within the …

Recreation, Fire And Disease Create A Mosaic Of Threats For Golden Eagles In Southwestern Idaho, Caitlin Marie Davis

Boise State University Theses and Dissertations

Anthropogenic stressors have resulted in ecosystem impoverishment and biodiversity loss worldwide. As the strength and reach of the human footprint increases, investigation of the additive or interactive effects of synergistic stressors on the landscape is imperative for conserving ecosystems and species within them. Apex predators can reflect how stressors impact ecosystems because of bottom-up effects. Golden eagles (Aquila chrysaetos) are apex predators of North American sagebrush-steppe ecosystems that are impacted by a suite of stressors, including wildfire, outdoor recreation disturbance, and habitat loss. We investigated whether multiple threats had additive or interactive effects on golden eagle occupancy, reproduction, …

Microbial Colonization Of Pneumatic Tourniquets In The Orthopedic Operating Room, Syed Hamza Mufarrih, Nada Qaisar Qureshi, Rizwan Haroon Rashid, Bilal Ahmed, Seema Irfan, Akbar Jaleel Zubair, Shahryar Noordin

Section of Orthopaedic Surgery

Background: The rate of surgical site infections following orthopedic procedures is approximately 2% globally. Potential sources of contamination in the operating room include pneumatic tourniquets, blood pressure cuffs, and stethoscopes, among others. Our study aims to investigate microbial colonization on reusable pneumatic tourniquets stored and used in the orthopedic department of our institution and evaluate the efficacy of the cleaning protocols employed. Methods: Over a course of two weeks, 26 samples were obtained. A total of 14 pneumatic tourniquets were sampled preoperatively on Monday morning following the weekly cleaning protocol of soaking the tourniquets in sodium hypochlorite for 30 minutes …

A Quasi-Experimental Study Of The Effect Of Experience Staging Techniques On Engagement, Emerson Ferrell Watanabe

Theses and Dissertations

The purpose of this study is to examine the effect of experience staging techniques (personalization through co-creation and multisensory stimuli) on engagement level. This study also explores the possible contribution of experience staging techniques as practical tools that recreation professionals can use to better engage participants in recreation activities and events. A 2-way univariate ANOVA revealed no significant relationship between the use of co-creative and multisensory stimulating techniques and engagement levels in participants (F (3,200) = .263, p = .826, partial η2 = .004). Practical applications for recreation professionals and further research opportunities are discussed.

Drawing Trump Naked: Curbing The Right Of Publicity To Protect Public Discourse, Thomas E. Kadri

Maryland Law Review

From Donald Trump to Lindsay Lohan to Manuel Noriega, real people who are portrayed in expressive works are increasingly targeting creators of those works for allegedly violating their “right of publicity”—a state-law tort that prohibits the unauthorized use of a person’s name, likeness, and other identifying characteristics. Intuitively, we might feel confident that Mark Zuckerberg should not be able to block his portrayal in The Social Network movie, that Marilyn Monroe could not have stopped Andy Warhol from exhibiting his vibrant paintings, that O.J. Simpson could not have demanded money from FX to air the American Crime Story docudrama. But …

Children Shouldn't Play With Dead Things, Sarah Adcock

Graduate School of Art Theses

I view my creative process as alchemy, the transformation of materials through experimentation. I use wax as a material that transcends its historical use as a sculptural process for casting and instead, use it for its transmutable qualities to inform content. Because of its plasticity and duality as fragile and resilient, wax is symbolically submissive and assertive. By applying heat, wax can be molded and formed into new shapes. Once it cools, wax reverts back to its natural state; solid and impermeable. I use objects to explore desires of origin and life. Transitional objects, the first “me not me” possession …

Do Psychopathic Traits Influence Distractibility By Empathy-Eliciting Pictures?, Priya M. Reji

Student Theses

Empathy is a crucial component in forming interpersonal connections, and reflects the ability to share and understand the feelings of others. Psychopathy is often associated with a reduced ability to feel and display empathetic concern towards other people. The Response Modulation Hypothesis argues that such individuals have an attentional deficit, which makes it difficult for them to shift focus between stimuli, thus individuals who have high scores on the interpersonal-affective factor of psychopathy have an increased ability to ignore emotional stimuli that are goal-irrelevant. The current study investigated whether psychopathic traits would influence distractibility on an emotional Stroop (eStroop) task. …

Amyloidogenicity Of Naturally Occurring Full-Length Animal Iapp Variants, Larry M. Palato, Shannon Pilcher, Alissa Oakes, Arleen Lamba, Jaris Torres, Litza I. Ledesma Monjaraz, Crystabel Munoz, Edward Njoo, Dillon J. Rinauro, Kate Alexandra Menefee, Angela Tun, Betssy L. Jauregui, Sarah Shapiro, Olivia H. Nossiff, Eileen Olivares, Kevin Chang, Viviane Nguyen, Luiza A. Nogaj, David A. Moffet

Chemistry and Biochemistry Faculty Works

Aim: To identify naturally occurring variants of IAPP capable of inhibiting the aggregation of human IAPP and protecting living cells from the toxic effects of human IAPP. Background: The loss of insulin-producing β-cells and the overall progression of type 2 diabetes appears to be linked to the formation of toxic human IAPP (hIAPP, Islet Amyloid Polypeptide, amylin) amyloid in the pancreas. Inhibiting the initial aggregation of hIAPP has the potential to slow, if not stop entirely, the loss of β-cells and halt the progression of the disease. Objective: To identify and characterize naturally occurring variants of IAPP capable of inhibiting …

The Effects Of Climate Change On The Heart Rates & Growth Of Sea Slugs In The Gulf Of Maine, Jennifer Leigh Gibson

Master's Theses and Capstones

In the next 80 years, sea surface temperatures are expected to increase by 1.5o to 2oC and ocean pH is expected to drop by 0.06 to 0.32 units, with exacerbated effects seen in coastal waters. Temperature increase has already forced organisms to shift their range polewards and ocean acidification has negatively affected calcifying organisms. Interactive effects, only more recently studied, vary depending on phylum and life cycle stage. This study examined both the upper thermal tolerance and interactive effect of temperature and acidification on the heart rate of five cold-water species of nudibranchs (Aeolidia papillosa, Cuthona gymnota, Dendronotus frondosus, Flabellina …

Systemic Immunologic Consequences Of Chronic Periodontitis, D. K. Gaudilliere, A. Culos, K. Djebali, Amy S. Tsai, Edward A. Ganio, W. M. Choi, Xiaoyuan Han, A. Maghaireh, B. Choisy, Q. Baca, J. F. Einhaus, J. J. Hedou, B. Bertrand, K. Ando, R. Fallahzadeh, Mohammad Sajjad Ghaemi, R. Okada, N. Stanley, A. Tanada, M. Tingle, T. Alpagot, J. A. Helms, M. S. Angst, N. Aghaeepour, B. Gaudilliere

All Dugoni School of Dentistry Faculty Articles

Chronic periodontitis (ChP) is a prevalent inflammatory disease affecting 46% of the US population. ChP produces a profound local inflammatory response to dysbiotic oral microbiota that leads to destruction of alveolar bone and tooth loss. ChP is also associated with systemic illnesses, including cardiovascular diseases, malignancies, and adverse pregnancy outcomes. However, the mechanisms underlying these adverse health outcomes are poorly understood. In this prospective cohort study, we used a highly multiplex mass cytometry immunoassay to perform an in-depth analysis of the systemic consequences of ChP in patients before (n = 28) and after (n = 16) periodontal treatment. A high-dimensional …

A Study Of Human Balance And Coordination Using A Head Mounted Display, Daniel Gracia De Luna

Theses and Dissertations

Virtual Reality (VR) is growing with new technologies and applications. The new technologies help the user to feel more immersed in virtual environments, but interaction and immersion is an area that has not been well studied. Immersion is the feeling and reaction of users while they are in a virtual environment. This investigation is focused on the study of the human balance and coordination when human subjects are inside a virtual environment. Over 60 subjects are studied under an experiment, where their trajectory is captured and analyzed to identify possible differences or similitudes between male and female subjects.

Essays On Alternative Investments, Chad Kwon

Theses and Dissertations

This dissertation considers the role of cultural traits in the markets for alternative investments. The latter refers to assets that are not traditionally discussed when building a financial portfolio for ordinary investors. These are subject to low turnover, high maintenance costs, and low liquidity for investors. These features distinguish them to be non-typical assets that demand more careful strategy to acquire, maintain, and sell these belongings. Nevertheless, investors are interested in these assets for the dual purposes of building equities and consuming benefits simultaneously during ownership. We focus on two types of durable assets—residential houses and paintings at art auctions—to …

The Prisoner As Object: Rhetorical Agency And The Literacy Of Prison Tattooing, Rebecca R. Reyes

Theses and Dissertations

Prison is an environment by which man is no longer a man. In an institution designed to limit the agency of incarcerated individuals, a literacy event has unfolded through the rhetorical practice of prison tattooing that allows individuals to re/gain their agency. Tattoos allow for the incarcerated, who are seen as state property, to break down the dehumanizing assemblage that has been created. The body, now an object, becomes a site for rhetorical communication where an emergent agency develops within the relationship of all intra-acting factors. I analyze and build upon ambient rhetoric, visual rhetoric, Kairos, and counternarratives to …

Stem Heroes: A Narrative-Based Intervention To Increase Self-Efficacy And Interest In Science, Technology, Engineering, And Mathematics In Elementary School-Aged Children, Lauren M. Carino

Seton Hall University Dissertations and Theses (ETDs)

Over time, researchers have struggled to identify effective interventions to support girls’ self-efficacy and interest in science, technology, engineering, and mathematics (STEM). The primary purpose of this study was to examine whether a theoretically-grounded narrative-based intervention would be able to increase elementary school-aged girls’ self-efficacy in respect to future careers and interest in STEM subjects in school. The study sought to do this by using the stories of the “Heroes of STEM”, a series of four graphic novels developed by the principal researcher, as an intervention tool linking girls’ typically preferred subject (i.e., reading, language arts) to math and science. …

Remote Sensing Of Explosives-Induced Stress In Plants: Hyperspectral Imaging Analysis For Remote Detection Of Unexploded Threats, Paul V. Manley, Vasit Sagan, Felix B. Fritschi, Joel Gerard Burken

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Explosives contaminate millions of hectares from various sources (partial detonations, improper storage, and release from production and transport) that can be life-threatening, e.g., landmines and unexploded ordnance. Exposure to and uptake of explosives can also negatively impact plant health, and these factors can be can be remotely sensed. Stress induction was remotely sensed via a whole-plant hyperspectral imaging system as two genotypes of Zea mays, a drought-susceptible hybrid and a drought-tolerant hybrid, and a forage Sorghum bicolor were grown in a greenhouse with one control group, one group maintained at 60% soil field capacity, and a third exposed to …

The Effects Of Urbanization On Avian Seed Dispersal Success Of Toxicodendron Radicans (Anacardiaceae), Aiden M. Stanley

Electronic Theses and Dissertations

Urbanization is increasing at a dramatic rate as the human population increases. While it is well-known that urbanization tends to decrease species diversity (i.e., biotic homogenization), it is not known how urbanization affects the frequency and efficiency of species interactions. Seed dispersal is a plant-animal interaction that depends on disperser feeding rate, disperser diversity, probability of seed dispersal and germination. How these factors are affected by urbanization however is unknown. In this study, we evaluate how urbanization alters these factors. Urban sites had 2x higher feeding rate and 3x higher number of disperser species. The probability of seed dispersal however …

Minding The Gaps In Lawyers' Rules Of Professional Conduct, Anita Bernstein

Faculty Scholarship

No abstract provided.

The Gsk-3Β-Fbxl21 Axis Regulates Tcap Via Ubiquitin-Mediated Proteasomal Pathway In The Cytoplasm, Jiah Yang

Dissertations and Theses (Open Access)

Protein turnover is one of the most essential mechanisms controlling circadian rhythms. F-Box and Leucine Rich Repeat Protein21 (FBXL21) is a circadian E3 ligase which shows oscillatory mRNA transcripts and protein levels. It was previously found to perform subcellular compartment-specific E3 ligase activities targeting the core clock proteins CRYPTOCHROME(CRY)1/2. Here we identified a new sarcomeric target substrate, Telethonin(TCAP), which also shows circadian oscillation in its mRNA transcript and protein expression and, importantly, interaction with FBXL21 in an anti-phasic manner. Via computational and pharmacological tests, we identified Glycogen Synthase Kinase-3β(GSK-3β) as a regulator of FBXL21. Biochemical and molecular characterizations demonstrated that …

Evaluating The Therapeutic Efficacy Of Grb2 Inhibition In Ovarian Malignancies, Olivia Lara

Dissertations and Theses (Open Access)

Purpose: Adaptor proteins such as growth factor receptor-bound protein-2 (Grb2) play important roles in cancer cell signaling. In the present study, we examined the biological effects of liposomal antisense oligodeoxynucleotide that blocks Grb2 expression (L-Grb2) in ovarian cancer models.

Experimental Design: Murine orthotopic models of ovarian cancer (OVCAR5 and SKOV3ip1) were used to study the biological effects of L-Grb2 on tumor growth. In vitro experiments (cell viability assay, Western blot analysis, siRNA transfection, and reverse phase protein array) were carried out to elucidate the mechanism and potential predictors of tumor response to L-Grb2.

Results: Treatment with L-Grb2 decreased tumor growth …

Identifying And Targeting Adaptive Changes To Bet Inhibition In Ovarian Cancer, Christopher Lafargue

Dissertations and Theses (Open Access)

Purpose: To identify combination strategies using Bromodomain and Extra-Terminal Domain (BET) inhibitors in a mechanism driven fashion to maximize anti-tumor activity, and to determine the efficacy of BET inhibitor combinations in pre-clinical ovarian cancer mouse models.

Experimental Design: We used a novel, previously uncharacterized pan-BET inhibitor, CN210, for all in vitro (MTT, apoptosis, protein expression, reverse phase protein array (RPPA) analysis and in vivo (orthotopic mouse model)) experiments. The poly (ADP-ribose) polymerase (PARP) inhibitor olaparib, as well as the mechanistic target of rapamycin (mTOR) inhibitors rapamycin and INK-128 were also used. Statistical analyses of in vitro and in vivo experiments …

A Framework For The Development, Design And Implementation Of A Sustained Arctic Ocean Observing System, Craig M. Lee, Sandy Starkweather, Hajo Eicken, Mary-Louise Timmermans, Jeremy Wilkinson, Stein Sandven, Dmitry Dukhovskoy, Sebastian Gerland, Jacqueline Grebmeier, Janet M. Intrieri, Sung-Ho Kang, Molly Mccammon, An T. Nguyen, Igor Polyakov, Benjamin Rabe, Hanne Sagen, Sophie Seeyave, Denis Volkov, Agnieszka Beszczynska-Möller, Léon Chafik, Matthew Dzieciuch, Gustavo Goni, Torill Hamre, Andrew Luke King, Are Olsen, Roshin P. Raj, Thomas Rossby, Øystein Skagseth, Henrik Søiland, Kai Sørensen

Graduate School of Oceanography Faculty Publications

Rapid Arctic warming drives profound change in the marine environment that have significant socio-economic impacts within the Arctic and beyond, including climate and weather hazards, food security, transportation, infrastructure planning and resource extraction. These concerns drive efforts to understand and predict Arctic environmental change and motivate development of an Arctic Region Component of the Global Ocean Observing System (ARCGOOS) capable of collecting the broad, sustained observations needed to support these endeavors. This paper provides a roadmap for establishing the ARCGOOS. ARCGOOS development must be underpinned by a broadly endorsed framework grounded in high-level policy drivers and the scientific and operational …

Rcrab: An R Analytics Tool To Visualize And Analyze The Movement Of Horseshoe Crabs In Long Island Sound, Ismael Youssef, Samah Senbel, Jo-Marie Kasinak, Jennifer Mattei

School of Computer Science & Engineering Faculty Publications

Mark-recapture programs are important for studying the ecology and population dynamics of wildlife. An R shiny analytics tool was developed to track the movement of horseshoe crabs in Long Island Sound based on tag and resight data. The crabs were tagged and recaptured by volunteers of Project Limulus, a community-based research program. The dataset contains tag and recapture location information for 14,065 horseshoe crabs over 18 years. The dataset was initially cleaned by removing records with missing, duplicate or incorrect data. A new data structure was developed to save the data and simplify processing: Three dimensions were used, one for …

A Survey Of College Students With Learning Disabilities And Attention Deficit Hyperactivity Disorder To Identify Their Relationship And Use Of College Disability Resource Centers, Telia M. West

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

College students with learning disabilities (LD) and/or attention deficit hyperactivity disorder (ADHD) complete college at lower rates than their non-disabled peers (Newman & Madaus, 2015). Colleges receiving federal funding are required to have a disability resource center (DRC) that provides and coordinates accommodations for students with disabilities. This project examined the factors that led students with LD and/or ADHD to initially contact their college DRC. This project examined data from 61 college students pursuing an undergraduate degree with LD and/or ADHD who had already contacted their DRC. A survey was sent to those students asking about circumstances surrounding their …

Licentious Legends: A Folklore Podcast, Alexandra L. Haynes

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Licentious Legends was created out of a need to both understand and educate about sexual contemporary legends; not just what they are and what defines them, but the effect that they have on those who experience them. The purpose of this podcast is not to shame, but to take what has been found and educate about the joys and dangers of these legends. These legends range from the everyday (such as "The Hook"), to legends about a young man killing himself with a plunger. In an effort to gather as many examples as they could, Faye interviewed several of their …

Infestation Intensities, Attachment Patterns, And The Effect On Host Contest Behavior Of The Tick Ixodes Pacificus On The Lizard Sceloporus Occidentalis, Dylan M. Lanser

Master's Theses

Parasites often have profound effects on the survival and evolution of their hosts, and hence on the structure and health of entire ecosystems. Yet basic questions, such as the degree of virulence of a given parasite on its host, and factors influencing which hosts in a population are at the greatest risk of infection, are vexingly difficult to resolve. The western blacklegged tick-western fence lizard (Ixodes pacificus-Sceloporus occidentalis) system is important, primarily because I. pacificus, a vector of the Lyme disease spirochete Borrelia burgdorferi, is dependent on S. occidentalis for blood meals in its subadult stages, …