Digital Commons Network^™

3d Printing Of Silk Fibroin-Based Hybrid Scaffold Treated With Platelet Rich Plasma For Bone Tissue Engineering, Liang Wei, Shaohua Wu, Mitchell Kuss, Xiping Jiang, Runjun Sun, Reid Patrick, Xiaohong Qin, Bin Duan

Department of Mechanical and Materials Engineering: Faculty Publications

3D printing/bioprinting are promising techniques to fabricate scaffolds with well controlled and patient-specific structures and architectures for bone tissue engineering. In this study, we developed a composite bioink consisting of silk fibroin (SF), gelatin (GEL), hyaluronic acid (HA), and tricalcium phosphate (TCP) and 3D bioprinted the silk fibroin-based hybrid scaffolds. The 3D bioprinted scaffolds with dual crosslinking were further treated with human platelet-rich plasma (PRP) to generate PRP coated scaffolds. Live/Dead and MTT assays demonstrated that PRP treatment could obviously promote the cell growth and proliferation of human adipose derived mesenchymal stem cells (HADMSC). In addition, the treatment of PRP …

The Impact Of Estradiol And Stress On Spatial Memory, Soniya Assudani Patel

Doctoral Dissertations

Spatial memory is a critical cognitive function that involves for navigating, interpreting, and representing environments, planning a route, remembering the location of an object or event, and understanding spatial configurations. The three studies presented are original investigations on how estradiol, anxiety, and stress influence hippocampal-dependent spatial memory. The first study assessed the impact of estradiol level on spatial memory in young adult women. Salivary assays were obtained to determine the exact estradiol level. Women at the high and low estradiol phases of their natural menstrual cycle were compared to each other and to women on oral contraceptives (OCs). Behavioral performance …

Milk Oligopeptide Inhibition Of (Α)-Tocopherol Fortified Linoleic Acid Oxidation, Haina Yuan, Jinyan Gong, Kun Tang, Jinge Huang, Gongnian Xiao, Jianmin Lv

Biological Engineering Student Research

This study investigated the effect of milk oligopeptides and (α)-tocopherol on inhibition of linoleic acid oxidation using Fe²⁺-vitamin C induced linoleic acid oxidation model through analysis of malondialdehyde, peroxide value, and conjugated diene and triene in the model. The alteration of milk oligopeptides maximal absorption wavelength, fluorescent feature, and secondary structure were further investigated to elucidate the interactions between milk oligopeptide and (α)-tocopherol that altered the inhibitory effect of linoleic acid oxidation. Results showed that Pro-Tyr-Tyr-Ala-Lys (PYYAK) and Ile-Pro-Ile-Gln-Tyr (IPIQY) with (α)-tocopherol significantly inhibited the oxidation of linoleic acid and reduced the formation of malondialdehyde by 38% and …

The Cosmological Empire Of Pliny The Elder: An Examination Of Political Themes In The Second Book Of The Historia Naturalis, Kevin Alan Mccormick

Dissertations and Theses

Pliny the Elder's Historia Naturalis, written in the 70s CE and perhaps left unfinished at its author's death in 79, is among the largest documents to have survived down to us from antiquity. It comprises some thirty-seven books on a breadth of topics about the natural world, and man's interaction with the world and marshalling of its resources. The work has often been referred to as the world's first encyclopedia. Recent scholarship has rescued Pliny's reputation from its degradation among the scholars of the early twentieth century, and modern scholars have approached the document via several analytical avenues, including …

Problem-Based Learning In Human Growth & Development Counselor Education, Javier F. Casado Pérez Ph.D. Ncc, Elliot Witherspoon Lpc

Teaching and Supervision in Counseling

As a core curricular standard that applies to all Council for the Accreditation of Counseling and Related Educational Programs (CACREP, 2015) accredited programs, human growth and development can present unique challenges for the teaching professional. In this article, we present an in-class activity grounded in problem-based learning that uniquely lends itself to the task of supporting medium-to-large classrooms in learning about human growth and development.

“All That Was Important In Life”: Toward A Compassionate Anthropocene In Tracy K. Smith’S “Watershed”, Isaac B. Robertson

BYU English Symposium

In Tracy K. Smith’s “Watershed,” the Pulitzer-prize winner and current Poet Laureate of America juxtaposes accounts of ecological violence with individual eschatological experiences. Having been “powerfully compelled and disturbed by a Nathaniel Rich article about chemical pollution that appeared in the New York Times Magazinein January 2016,”¹Smith knew that she wanted to compose a found poem using lines of the report, although she didn’t know at the time what form that would take. Later, she “had the idea of marrying the facts from that article . . . with the narratives of near-death-experience (NDE) survivors.” Yet while …

Contributors, Marvels & Tales Editors

Marvels & Tales

No abstract provided.

Reviews, Marvels & Tales Editors

Marvels & Tales

No abstract provided.

Keynote 2: Student Choice (What Can Student-Directed Learning Look Like?), Joe Ruhl

Faculty Technology Showcase

Moving from a teacher-centered classroom to a student-centered classroom creates a “teacher paradox,” because on the surface, the teacher appears to become the least important person in the classroom. But in transitioning from a “sage on the stage” to a “guide on the side” (while team teaching with a fleet of classroom computers), the teacher’s impact on the lives of the students is actually enhanced. How does one design units of instruction that are student-centered? Come and find out how one high school teacher has attempted to pull this off.

Influence Of Gut Microbiome On Obesity In Western-Style Dietary Practices Versus Other Diets: A Systematic Review, Keely A. Niemeyer, Doris I. Buezo, Loren Landeros, Karina Corral

OSRI Journal of Student Research and Innovation

BACKGROUND: The human gut is home to a microbiome that has a complex relationship to human health. Like the human genome project, microbiome is catching the attention of researchers who seek new methods to combat obesity and negative health outcomes associated with it.

OBJECTIVES: This systematic review aims to distinguish the impact of a Western diet on gut health verses a plant-based diet.

DATA SOURCES: EBSCOHost library databases inclusive of CINAHL plus, ScienceDirect, and PubMed using keywords to better understand the correlation of dietary practices and microbiome balance.

STUDY ELIGIBILITY: Criteria that include diet, current research, and scholarly peer reviewed …

Agenesis Of The Corpus Callosum Is Associated With Developmental Delay And Intellectual Disability, Quinton J. Mandle

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Romaniello R, Marelli S, Giorda R, et al. Clinical characterization, genetics, and long-term follow-up of a large cohort of patients with agenesis of the corpus callosum. Journal of Child Neurology, 2016;32(1):60-71. doi: 10.1177/0883073816664668.

The Physiological And Molecular Mechanisms Of The Nitrogen Excretion In Mahi-Mahi (Coryphaena Hippurus) And Zebrafish (Danio Rerio), Yadong Wang

Open Access Dissertations

Many ecologically important fishes, including mahi-mahi (Coryphaena hippurus), and their offspring were directly exposed to crude oil following the Deepwater Horizon (DWH) oil spill. Early life stage fish are especially vulnerable to the toxicity of crude oil-derived polycyclic aromatic hydrocarbons (PAHs). In teleosts, yolk sac proteins are the main energy source during development and are usually catabolized into ammonia or urea. Although excretion of these waste products is sensitive to oil exposure, we know little about the underlying mechanisms of this process. This dissertation sought to investigate the ontogeny of ammonia and urea handling in the early life …

Idsc Opinion - Homeland Determination, Justice John Stegner

In re CSRBA (Coeur d'Alene)

The Idaho Supreme Court reversed the district court’s decisions as follows: first, the district court improperly applied New Mexico’s primary-secondary distinction and instead should have analyzed the claims from the perspective of what the Tribe needed to establish a homeland. Under that framework, the district court should have allowed aboriginal purposes of plant gathering and cultural uses; second, the priority date associated with nonconsumptive water rights on lands reacquired by the tribe was found to be time immemorial. The Court affirmed the remainder of the district court’s decisions and remanded for proceedings consistent with the opinion

Program Review: Philosophy Program, University Of Nebraska At Kearney Philosophy Program

Academic Program Reviews

No abstract provided.

Vol.48 N.07 September 5th 2019, Voice Media Ventures

Black Voice News

No abstract provided.

September 5, 2019, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

The Indiana Statesman, September 5, 2019, Indiana State University

Student Newspaper

Emotional Support Animals can benefit ISU students; Sasha Obama set to begin college career at University of Michigan; Man who allegedly supplied Mac Miller with fentanyl-laced pills is arrested; Hurricane Dorian gets stronger as it zeroes in on Carolinas coast

Sworn To Secrecy: The Ethics Of Confidentiality Agreements, Rachel Robinson-Greene

Languages, Philosophy, and Communication Studies Faculty Publications

On August 31st, President Trump revealed that he is currently “suing various people for violating their confidentiality agreements.” This kind of behavior from the President is unremarkable because it has happens so often. In the highest profile case, President Trump had Stormy Daniels, a woman with whom he was having an adulterous affair, sign a non-disclosure agreement, promising that she would not speak about the nature of their relationship.

Use Of Probiotic Bacterial Strains And Cell Extracts To Inhibit Acidosis And Liver Abscesses In Cattle, Samodha Charaka Fernand

Department of Animal Science: Faculty Publications

Disclosed are methods of using probiotic bacterial strains Aneurinibacillus migulanus, Aneurinibacillus aneurinilyti cus and / or extracts thereof for inhibiting the growth of Streptococcus bovis , Fusobacterium necrophorum , and Acranobacterium ( Actinomyces ) pyogenes . These bacterial strains and / or their extracts can be used in cattle to treat acidosis and / or liver abscesses , as well as inhibit foot rot, among other infections and conditions caused by Strepto coccus bovis and / or Fusobacterium necrophorum and / or Acranobacterium (Actinomyces) pyogenes. Compositions for use in these methods are also provided.

Biomarker Identified For Early Beta Cell Death In Type 1 Diabetes, Jeff Hansen

Browse All News

No abstract provided.

Virus-Induced Cochlear Inflammation In Newborn Mice Alters Auditory Function, Cathy Yea Won Sung, Maria C. Seleme, Shelby Payne, Stipan Jonjic, Keiko Hirose, William Britt

Open Access Publications

Although human cytomegalovirus (HCMV) is a known cause of sensorineural hearing loss in infants with congenital HCMV (cCMV) infections, mechanisms that contribute to sensorineural hearing loss (SNHL) in infants with cCMV infection are not well defined. Using a murine model of CMV infection during auditory development, we have shown that peripheral infection of newborn mice with murine CMV (MCMV) results in focal infection of the cochlea and virus-induced cochlear inflammation. Approximately 50%-60% of infected mice exhibited increased auditory brainstem response (ABR) thresholds across a range of sound frequencies. Histological analyses of the cochlea in MCMV-infected mice with elevated ABR thresholds …

Daily Eastern News: September 05, 2019, Eastern Illinois University

September

No abstract provided.

Altered Gating Of KV1.4 In The Nucleus Accumbens Suppresses Motivation For Reward, Bernadette O'Donovan, Adewale Adeluyi, Erin L Anderson, Robert D. Cole, Jill R. Turner, Pavel I. Ortinski

Neuroscience Faculty Publications

Deficient motivation contributes to numerous psychiatric disorders, including withdrawal from drug use, depression, schizophrenia, and others. Nucleus accumbens (NAc) has been implicated in motivated behavior, but it remains unclear whether motivational drive is linked to discrete neurobiological mechanisms within the NAc. To examine this, we profiled cohorts of Sprague-Dawley rats in a test of motivation to consume sucrose. We found that substantial variability in willingness to exert effort for reward was not associated with operant responding under low-effort conditions or stress levels. Instead, effort-based motivation was mirrored by a divergent NAc shell transcriptome with differential regulation at potassium and dopamine …

Geographical Analysis Of Proposed Nature Reserves In Muthanna Governorate, Anwar Sabah Mohammed Al-Kalabi

Uruk Journal of Human Sciences

The present study is based on analyzing the natural geographical potentials in Muthanna Governorate and its suitability for the establishment of natural reserves and their development. The areas studied as nature reserves were of two types, namely, wild reserves. These included three sites in Badia, Muthanna Governorate (Hadaniya, , Rifaiya) in the district of Salman, and the Wadi Al-Dhobaa Valley in the area of ​​Basayeh. The second type was the aqueducts, which included two sites, the Sawa Lake Reserve and a low-lying reserve. She also studied the Western Sawa Wildlife Reserve of the Directorate of Muthanna Agriculture, which includes the …

Evaluation Of Epas1 Variants For Association With Bovine Congestive Heart Failure [Version 1; Peer Review: 2 Approved], Michael P. Heaton, Adam S. Bassett, Katherine J. Whitman, Greta M. Krafsur, Sang M. Lee, Jaden M. Carlson, Halden J. Clark, Helen R. Smith, Madeline C. Pelster, Veronica Basnayake, Dale M. Grotelueschen, B. Vander Ley

School of Veterinary and Biomedical Sciences: Faculty Publications

Background: Bovine congestive heart failure (BCHF) has become increasingly prevalent in feedlot cattle in the Western Great Plains of North America. BCHF is an untreatable complex condition involving pulmonary hypertension that culminates in right ventricular failure and death. A protein variant of hypoxia-inducible factor 2 alpha (HIF2α, encoded by the endothelial PAS domain-containing protein 1 gene, EPAS1) was previously reported to be associated with pulmonary hypertension at altitudes exceeding 2,000 m. Our aim was to evaluate EPAS1 haplotypes for association with BCHF in feedlot cattle raised at moderate altitudes (1,200 m).

Methods: Paired samples of clinical cases and unaffected controls …

A Silent Epidemic With No Voice: Alzheimer's Education In An African American Midwest Community, Sandra D. Fields

Dissertations

Alzheimer’s disease is a growing crisis in this country, particularly in the African American community. Despite this awareness by the health care community and educational programs offered about the disease, a deficit in research assessing the impact of these programs exists. Consequently, the purpose of this study is to analyze the key criterion relative to the educational programs about Alzheimer’s offered by local organizations and the impact they have on a Midwest African American community.

According to research regarding Alzheimer’s disease, African Americans continue to go undiagnosed and untreated. The literature review in this study explores the synergy of three …

The Role Of Bilingual Interactional Contexts In Predicting Interindividual Variability In Executive Functions: A Latent Variable Analysis, Andree Hartanto, Hwajin Yang

Research Collection School of Social Sciences

Despite a growing number of studies on bilingual advantages in executive functions (EF), their findings have been inconsistent. To shed light on this issue, we aimed to address both the conceptual and methodological limitations that have prevailed in the literature: failure to consider diverse bilingual experiences when assessing bilingual advantages or to address the task impurity problems that can arise with EF tasks. Drawing on the adaptive control hypothesis and control process model of code-switching, we adopted theory-driven and latent variable approaches to examine the relations between bilingual interactional contexts and EF. By administering 9 EF tasks to 175 bilingual …

Vincristine And Bortezomib Use Distinct Upstream Mechanisms To Activate A Common Sarm1-Dependent Axon Degeneration Program, Stefanie Geisler, Ryan A Doan, Galen C Cheng, Aysel Cetinkaya-Fisgin, Shay X Huang, Ahmet Höke, Jeffrey Milbrandt, Aaron Diantonio

Open Access Publications

Chemotherapy-induced peripheral neuropathy is one of the most prevalent dose-limiting toxicities of anticancer therapy. Development of effective therapies to prevent chemotherapy-induced neuropathies could be enabled by a mechanistic understanding of axonal breakdown following exposure to neuropathy-causing agents. Here, we reveal the molecular mechanisms underlying axon degeneration induced by 2 widely used chemotherapeutic agents with distinct mechanisms of action: vincristine and bortezomib. We showed previously that genetic deletion of SARM1 blocks vincristine-induced neuropathy and demonstrate here that it also prevents axon destruction following administration of bortezomib in vitro and in vivo. Using cultured neurons, we found that vincristine and bortezomib converge …

Kenyon Collegian - September 5, 2019

The Kenyon Collegian

No abstract provided.

Silicon Fertilization In Rice And Wheat: Dynamics With Trace Elements And Effect Of Silicate Slag Granular Size On The Release Pattern Of Monosilicic Acid In Soil, Wooiklee S. Paye

LSU Doctoral Dissertations

Studies were conducted to evaluate the impact of silicon (Si) fertilization on the uptake of harmful trace elements in Louisiana rice production system, and document the effect of silicate slag granular size on its ability to supply Si in wheat. The influence of silicate slag and lime on the uptake and translocation of harmful trace elements in rice grain was determined. Results showed that both slag and lime had similar effects on pH at five of the nine sites investigated. Soil Si was significantly (P <0.001) increased with application of silicate slag at all sites. Lime and silicate slag had no effect on the concentration of trace elements in soil. However, increasing Si rates were negatively correlated with arsenic (As) and cadmium (Cd) concentration in rice grain. The release pattern of monosilicic acid (H₄SiO₄) from wollastonite and silicate slag was compared in a wheat greenhouse …