Digital Commons Network^™

How To Solve The Problem Of Evil: A Deontological Strategy, Justin Mooney

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Mikel Burley, Ed., Wittgenstein, Religion And Ethics: New Perspectives From Philosophy And Theology, Charles Guth Iii, Griffin Klemick

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Is The Cosmos Fine-Tuned For Life, Or For The Possibility Of Life? (And Why Patristic And Medieval Demonology Might Hold Part Of The Answer), Travis Dumsday

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Textbook List, Fall 2019, Office Of Registrar

Semester Schedules and Information

No abstract provided.

Course List, Fall 2019, Office Of Registrar

Semester Schedules and Information

No abstract provided.

Class Schedule - Fall 2019, Office Of Registrar

Semester Schedules and Information

No abstract provided.

Disguised Patent Policymaking, Saurabh Vishnubhakat

Faculty Scholarship

Patent Office power has grown immensely in this decade, and the agency is wielding its power in predictably troubling ways. Like other agencies, it injects politics into its decisions while relying on technocratic justifications. It also reads grants of authority expansively to aggrandize its power, especially to the detriment of judicial checks on agency action. However, this story of Patent Office ascendancy differs from that of other agencies in two important respects. One is that the U.S. patent system still remains primarily a means for allocating property rights, not a comprehensive regime of industrial regulation. Thus, the Patent Office cannot …

Text By Mus, Mustafa Abubaker

Graduate Scholarly Works

This is why I have created a Twitter bot to generate interactive thread-based creative writing in the form of short stories called Text By Mus as my interactive media project in the graduate level course Web Content Development: Writing for Interactive Media PRWR 6850 instructed by Dr. Sergio Figueiredo. The account features “choose your own adventure” stories written in the literary fiction style. I would like to use the Twitter bot to combat the mass-market production of what is called literature in lieu of digital fiction being just as good as classical, all-time great fiction. This project presents a software …

Fall 2019

Scientia

Education Taking Flight; The Vincentian Question and the Chemistry Teacher; Science Goes Global; Minister of Hope: Neurosurgeon and cancer researcher Alfredo Quinones-Hinojosa, MD, believes hope is more powerful than fear; What's New: The college introduced four new programs and tracks in its offerings for the 2019-20 academic year; Lab Notes; A Teacher Who Really Counts: Golden Apple Recipient Candice Cortese (CSH MA '10) Reflects on her Love of Teaching Math; One Smart Cookie: Chemistry Student Lucienna Wolf Says, "If You Really Apply Yourself, the Teachers Are More Than Happy to Help You."

World Changers: Seeing Beyond The Majority, Seventh-Day Adventist Theological Seminary

Current: Faith Meets Life and Culture

No abstract provided.

Stub1 Suppresseses Tumorigenesis And Chemoresistance Through Antagonizing Yap1 Signaling, Dong-E Tang, Yong Dai, Lie-Wen Lin, Yong Xu, Dong-Zhou Liu, Xiao-Ping Hong, Hao-Wu Jiang, Song-Hui Xu

Open Access Publications

Yes-associated protein (YAP) is a component of the canonical Hippo signaling pathway that is known to play essential roles in modulating organ size, development, and tumorigenesis. Activation or upregulation of YAP1, which contributes to cancer cell survival and chemoresistance, has been verified in different types of human cancers. However, the molecular mechanism of YAP1 upregulation in cancer is still unclear. Here we report that the E3 ubiquitin ligase STUB1 ubiquitinates and destabilizes YAP1, thereby inhibiting cancer cell survival. Low levels of STUB1 expression were correlated with increased protein levels of YAP1 in human gastric cancer cell lines and patient samples. …

Association Of Circulating Ceramides With Cardiac Structure And Function In The Community: The Framingham Heart Study, Chike C Nwabuo, Meredith Duncan, Vanessa Xanthakis, Linda R Peterson, Gary F Mitchell, David Mcmanus, Susan Cheng, Ramachandran S. Vasan

Open Access Publications

Background A higher circulating plasma ceramide ratio (C16:0/C24:0) is associated with an increased risk of heart failure, even after accounting for standard risk factors including lipid markers. However, the pathobiological mechanisms that underlie this association are incompletely understood. We tested the hypothesis that plasma ceramide ratio (C16:0/C24:0) is associated with adverse cardiac remodeling in the community. Methods and Results We evaluated 2652 Framingham Offspring Study participants (mean age, 66±9 years; 55% women) who attended their eighth examination cycle and underwent routine echocardiography and liquid chromatography-tandem mass spectrometry-based assays for circulating ceramide concentrations. We used multivariable linear regression models to relate …

Astrovirus Replication In Human Intestinal Enteroids Reveals Multi-Cellular Tropism And An Intricate Host Innate Immune Landscape, Abimbola O. Kolawole, Andrew B Janowski, David Wang, Christiane E. Wobus, Et Al.

Open Access Publications

Human astroviruses (HAstV) are understudied positive-strand RNA viruses that cause gastroenteritis mostly in children and the elderly. Three clades of astroviruses, classic, MLB-type and VA-type have been reported in humans. One limitation towards a better understanding of these viruses has been the lack of a physiologically relevant cell culture model that supports growth of all clades of HAstV. Herein, we demonstrate infection of HAstV strains belonging to all three clades in epithelium-only human intestinal enteroids (HIE) isolated from biopsy-derived intestinal crypts. A detailed investigation of infection of VA1, a member of the non-canonical HAstV-VA/HMO clade, showed robust replication in HIE …

Transcriptional And Epigenetic Regulation Of Cardiac Electrophysiology, Jesus Jimenez, Stacey L Rentschler

Open Access Publications

Spatiotemporal gene expression during cardiac development is a highly regulated process. Activation of key signaling pathways involved in electrophysiological programming, such as Notch and Wnt signaling, occurs in early cardiovascular development and these pathways are reactivated during pathologic remodeling. Direct targets of these signaling pathways have also been associated with inherited arrhythmias such as Brugada syndrome and arrhythmogenic cardiomyopathy. In addition, evidence is emerging from animal models that reactivation of Notch and Wnt signaling during cardiac pathology may predispose to acquired arrhythmias, underscoring the importance of elucidating the transcriptional and epigenetic effects on cardiac gene regulation. Here, we highlight specific …

A Human Stat1 Gain-Of-Function Mutation Impairs Cd8 + T Cell Responses Against Gammaherpesvirus 68, Wei Qian, Cathrine A Miner, Harshad Ingle, Derek J Platt, Megan T Baldridge, Jonathan J Miner

Open Access Publications

Autosomal dominant STAT1 mutations in humans have been associated with chronic mucocutaneous candidiasis (CMC), as well as with increased susceptibility to herpesvirus infections. Prior studies have focused on mucosal and Th17-mediated immunity against

Enrollment Report, Fall 2019, Planning, Research, And Policy Analysis

Enrollment Reports (2004-2019)

Enrollment Report for Fall 2019 for Illinois State University

From Traps To Snapshots: Examining The Ecology Of Feral Predators And Native Small Mammals In Southeastern Australia Through Case Studies Of Two Faunal Sampling Methods, Katherine Karson

Independent Study Project (ISP) Collection

The red fox (Vulpes vulpes) and feral cat (Felis catus) are introduced mesopredators that significantly threaten native small mammal species in Australia. For decades, environmental managers have attempted to mitigate the effects of these introduced species. However, ecosystems are highly complex, making it difficult to assess the impacts of feral predators on communities of native fauna independent of other disturbances such as fire regime and habitat fragmentation. Cost-effective ecological monitoring programs are imperative for evaluating threats to native species and informing environmental decisions. New technology has become increasingly present in wildlife monitoring, and camera trapping has provided an alternative to …

Swagriculture: A Qualitative Examination Of Women’S Participation In Samoa’S Agriculture Industry As Farmers And Growers, Charlotte Crandall

Independent Study Project (ISP) Collection

This study is an examination of how women participate in agriculture in Samoa as farmers and growers, what hardships women encounter and how they overcome these, and the organizations that influence people’s experiences. Censuses have historically undercounted the number of women in agriculture in developing countries, largely due to rigid international definitions of what counts as labor, which overlook cultural nuances, and this study aims to fill this gap in research. Data was collected through nine Talanoa-inspired interviews with women involved with farming or growing in Samoa, and overarching themes were analyzed. The themes have been grouped by the specific …

An Analysis Of The Rajasthan Public Health System’S Response To The 2019 Dengue Insurgence, Luke Bryan

Independent Study Project (ISP) Collection

Dengue virus is in a pandemic status and is a major public health issue in the modern world. The mosquito-borne disease is largely prevalent in Asia and specifically India, where more than half of the states are considered to have complete presence of the dengue virus. The intricate infrastructure of the Indian public health system looks for dengue cases at all levels and reports to the integrated disease surveillance programme (IDSP).

Analyses of the IDSP and trends of dengue cases was done in response to dengue outbreaks throughout the state. Geographic information system (GIS) maps were created to evaluate a …

What About The Environment?: Exploring The Neglected Third Dimension Of Antimicrobial Resistance, Paige E. Montfort

Independent Study Project (ISP) Collection

Antimicrobial resistance (AMR) is one of the most urgent and complex health risks of our time, with links to human health, animal health, and the environment. The majority of research and policy related to AMR, however, has been dedicated to human and animal health. The third dimension — the environment — has been relatively neglected. Conversations about this problem have begun, but gaps in understanding remain. This study explores the key barriers that have hindered developments related to the environmental aspect of AMR and some of the solutions that have begun to or could be utilized to overcome these barriers. …

La Ciudad Versus El Campo: La Calidad De Vida De Los Adultos Mayores Aymara Entre Arica Y Putre, Clare Rogowski

Independent Study Project (ISP) Collection

The elderly population in Chile is increasing rapidly. In indigenous villages in the interior of Chile, like Putre, the younger generation is leaving to pursue education and employment opportunities in cities, in this case Arica. In many cases no one stays to take care of the elders. As the elderly begin to grow older and require greater support, the younger generation seeks to move their family members to the city so that they can care for them. While this provides for greater connection to family and access to medical care for the elderly relatives, the elderly loses their connection to …

“Para Nunca Más Vivirlo, Nunca Más Negarlo”: El Legado De Violencia Sexual Durante La Dictadura, Isabel De La Torre

Independent Study Project (ISP) Collection

Research Question: What are the mental health effects of sexual political violence against women during the dictatorship and during the current socio-political movement?

Objectives: The general objective of this study is to identify how sexual political violence has been used in Chile against women and to analyze its consequences on the mental health of survivors. More specifically, this study attempts to investigate the mechanisms sexual political torture during the dictatorship and now, visibilize the unique damages to mental health caused by this type of violence, and analyze the dictatorial legacy in regards to sexual violence and the current socio-political climate. …

Cambios En El Cronograma De Temporadas Reproductivas De Pingüinos De Magallanes (Spheniscus Magellanicus): Relaciones Entre Eventos Fenológicos Y Variables Climáticas, Grace Neumiller

Independent Study Project (ISP) Collection

Estudios a largo plazo han demostrado que hay fluctuaciones a lo largo de la fenología de la vida silvestre a causa de los cambios climáticos (Black, 2016). Los pingüinos de Magallanes (Spheniscus magellanicus) exhiben cambios en el cronograma de los eventos fenológicos de sus temporadas reproductivas a causa de variables oceanográficas y climáticas de su ambiente. A partir de fotos de cámaras trampas, este trabajo describe y analice algunos eventos en la fenología de los pingüinos de Magallanes en Isla Martillo, Canal Beagle, Tierra del Fuego, Argentina: el inicio de la temporada reproductiva, el periodo de muda de pichones, y …

Designing An Accessible Wave Energy Conversion Device For Powering Ocean Sensors, Sophie Coppieters ‘T Wallant

Independent Study Project (ISP) Collection

Currently, less than 5% of our oceans are comprehensively monitored and much more ocean data is needed to facilitate understanding of ocean physics, carbon cycling, and ocean ecosystems. Today, most autonomous ocean sensors are powered by primary battery, which have both limited capacity and lifetime. The goal of this research is to design a small, accessible renewable wave energy device to power autonomous free-floating ocean sensors. By designing a cheap, accessible, and simple wave energy converter, this work hopes to make ocean sensor deployment easier and cheaper for researchers, increase the lifetime of autonomous ocean sensors, and reduce the reliance …

An Evaluation Of Soils On Sólheimajökull Glacier Foreland: Using Invertebrates And Decomposition As Bio-Indicators Of Soil Quality, Carolyn Weisman

Independent Study Project (ISP) Collection

Anthropogenic climate change has led to the retreat of glaciers globally. As glaciers melt, they expose the underlying land- termed the glacier foreland. These forelands provide a natural laboratory for studying ecological succession after a massive disturbance, which is in this case glaciation. In this study, soil invertebrates and decomposition are used as bio-indicators of the soil quality in the foreland of Sólheimajökull Outlet Glacier. Soil cores were collected from five sites (A-E) located 300m apart moving away from the glacier terminus. The abundance of each observed invertebrate taxa and the dissolved oxygen (DO) levels were taken for 30 soil …

(Wp 2019-02) A Road Not Taken? A Brief History Of Care In Economic Thought, John B. Davis, Robert Mcmaster

Economics Working Papers

Care is central to the human experience and part of the social provisioning process. Adam Smith recognized this, associating care with sympathy. Later contributions in the political economy tradition also provide scope for an analysis of care, but none as developed as Smith’s. With the emergence of the current mainstream, care is marginalized. Kenneth Boulding’s analysis provides an opportunity to interrogate care in the economy, but he fails to explicitly acknowledge care. It is left to feminist economics to highlight the centrality of care. An implication is that it challenges the conventional rubric of economic organization predicated on self-interest.

Experienced Males Recognise And Avoid Mating With Non-Virgin Females In The Western Flower Thrips, Adeyemi O. Akinyemi, William D.J. Kirk

All Peer-Reviewed Publications

The western flower thrips Frankliniella occidentalis (Thysanoptera: Thripidae) is a major insect pest on a wide range of crops throughout the world. There are several unexplained aspects of the mating behaviour, particularly in relation to male-male competition and mate choice. The objectives of the study were to test whether males can detect the mating status of females and whether males avoid mating with previously mated females. Experiments involved either 'experienced' adults taken from a laboratory culture, which had been exposed to high densities of thrips, or virgin adults reared individually. Experienced males mated readily with virgin females, but avoided mating …

Psychometric Analysis Of The Medical Terminology 350 Final Test Using Item Analysis And Kr20, Kristen Nicole Bowers

Doctoral Dissertations and Projects

Meaningful quantitative research studies require the use of instruments that have acceptable validity and reliability. The purpose of this study was to determine the reliability and validity of the Medical Terminology 350 Final Test (MT350) in a population of secondary health science students. The MT350 is an assessment instrument that measures participants’ recall of medical terminology meanings and is currently being used to assess learning in health science education. A review of literature has revealed a lack of psychometric analysis of the commonly used MT350. Past practice has suggested instruction that uses mnemonics can favorably influence medical vocabulary retention, but …

Behavioral And Immunohistochemical Characterization Of Rapid Reconditioning Following Extinction Of Contextual Fear, Amy R. Williams, Earnest S. Kim, K Matthews Lattal

Faculty Publications - Psychology Department

A fundamental property of extinction is that the behavior that is suppressed during extinction can be unmasked through a number of postextinction procedures. Of the commonly studied unmasking procedures (spontaneous recovery, reinstatement, contextual renewal, and rapid reacquisition), rapid reacquisition is the only approach that allows a direct comparison between the impact of a conditioning trial before or after extinction. Thus, it provides an opportunity to evaluate the ways in which extinction changes a subsequent learning experience. In five experiments, we investigate the behavioral and neurobiological mechanisms of postextinction reconditioning. We show that rapid reconditioning of unsignaled contextual fear after extinction …

Developing Herd Health Education For And Assessing Risky Practices Of Cow-Calf Producers, Andrew J. Allen, Donald A. Llewellyn, Susan R. Kerr, Tipton D. Hudson, J. Shannon Neibergs, Sarah M. Smith, Dale A. Moore

Journal of Extension

Bovine respiratory disease (BRD) is an often unrecognized problem in cow-calf herds. We describe a program we used to help producers identify and avoid practices that could increase their herds' risk for BRD. The greatest knowledge gains occurred for the topics of costs associated with BRD, BRD risks at the feedlot, and biosecurity measures. Through producer self-assessments, we found that the number of risky practices conducted by producers ranged from none to 22 per operation, averaging 10 per operation. Extension professionals should consider combining producer self-assessment with education on management as an effective strategy for informing producers of risks in …