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2019

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Body Condition Helps To Explain Metabolic Rate Variation In Wolf Spiders, Stella F. Uiterwaal, John P. Delong Jan 2019

Body Condition Helps To Explain Metabolic Rate Variation In Wolf Spiders, Stella F. Uiterwaal, John P. Delong

School of Biological Sciences: Faculty Publications

1. Metabolism is the fundamental process that powers life. Understanding what drives metabolism is therefore critical to our understanding of the ecology and behavior of organisms in nature.

2. Metabolic rate generally scales with body size according to a power law. However, considerable unexplained variation in metabolic rate remains after accounting for body mass with scaling functions.

3. We measured resting metabolic rates (oxygen consumption) of 227 field-caught wolf spiders. Then, we tested for effects of body mass, species, and body condition on metabolic rate.

4. Metabolic rate scales with body mass to the 0.85 power in these wolf spiders, …


Modeling Genomes To Phenomes To Populations In A Changing Climate: The Need For Collaborative Networks, Nika Galic, Allyson G. Hindle, John P. Delong, Karen Watanabe, Valery Forbes, C. Loren Buck Jan 2019

Modeling Genomes To Phenomes To Populations In A Changing Climate: The Need For Collaborative Networks, Nika Galic, Allyson G. Hindle, John P. Delong, Karen Watanabe, Valery Forbes, C. Loren Buck

School of Biological Sciences: Faculty Publications

Condensed Abstract

Climate is changing globally and its impacts can arise at different levels of biological organization; yet, cross-level consequences of climate change are still poorly understood. Designing effective environmental management and adaptation plans requires implementation of mechanistic models that span the biological hierarchy. Because biological systems are inherently complex and dynamic in nature, dealing with complexities efficiently necessitates simplification of systems or approximation of relevant processes, but there is little consensus on mathematical approaches to scale from genes to populations. Here we present an effort that aims to bring together groups that often do not interact, but that are …


Distribution Extension Of Aspiculuris Americana Parasite Of Peromyscus Difficilis In Hidalgo, Mexico, Griselda Pulido-Flores, Scott Monks, Jorge Falcón-Ordaz Jan 2019

Distribution Extension Of Aspiculuris Americana Parasite Of Peromyscus Difficilis In Hidalgo, Mexico, Griselda Pulido-Flores, Scott Monks, Jorge Falcón-Ordaz

Harold W. Manter Laboratory of Parasitology: Faculty Publications

English: As a part of an ongoing project to inventory the helminth parasites of rodents in Mexico, 30 individuals of Aspiculuris americana were collected inhabiting the intestine from three specimens of the rock mouse Peromyscus difficilis, collected from Cerro Xihuingo, Municipality of Tepeapulco, Hidalgo State, Mexico. This species of nematode parasite different species of the genus Peromyscus (P. gossypinus, P. leucopus, P. maniculatus, and P. floridanus) distributed from Yukon Territory in Canada to Florida in the United States of America. This is the first report of Aspiculuris americana in a Mexican endemic rodent, widening …


Pine-Wood Derived Nanobiochar For Removal Of Carbamazepine From Aqueous Media: Adsorption Behavior And Influential Parameters, Mitra Naghdi, Mehrdad Taheran, Rama Pulicharla, Tarek Rouissi, Satinder K. Brar, M. Verma, R. Y. Surampalli Jan 2019

Pine-Wood Derived Nanobiochar For Removal Of Carbamazepine From Aqueous Media: Adsorption Behavior And Influential Parameters, Mitra Naghdi, Mehrdad Taheran, Rama Pulicharla, Tarek Rouissi, Satinder K. Brar, M. Verma, R. Y. Surampalli

Department of Civil and Environmental Engineering: Faculty Publications

In recent years, application of biochar for removal of pollutants from aqueous solutions has been of interest due to favorable physicochemical properties and availability of feedstock. However, adsorption behavior has been reported only for raw and micro biochar particles and taking advantage of biochar nanoparticles, which offer superior specific surface area, did not receive any attention. The objective of this study was to investigate the adsorption efficiency of produced nanobiochar from pinewood. For this purpose, removal of carbamazepine (CBZ), a globally prescribed pharmaceutical, at very low concentrations (0.5–20 ppb) on as-produced nanobiochar with average particle size of 60 nm was …


Systems And Methods For Construction Of Electrically Conductive Concrete Slab With Protection From Current Leakage, Christopher Tuan, Lim Nguyen Jan 2019

Systems And Methods For Construction Of Electrically Conductive Concrete Slab With Protection From Current Leakage, Christopher Tuan, Lim Nguyen

Department of Civil and Environmental Engineering: Faculty Publications

Systems and methods for a conductive concrete slab having protection against one or more of surface current, ground fault current, and current leakage. A method includes, but is not limited to, introducing an electrical insulation base layer to a ground surface; introducing a plurality of electrodes to the electrical insulation base layer; and casting conductive concrete over the plurality of electrodes and the electrical insulation base layer. An electrical insulation top layer can also be applied to mitigate one or more of surface current and ground fault current.


Memory, Language, And Healing, Isabel Velázquez Jan 2019

Memory, Language, And Healing, Isabel Velázquez

Spanish Language and Literature Papers

One morning on a spring day not unlike the one during which I write these lines, Dr. Marie Chantal Kalisa came into my office and gifted me with a word. It wasn't a strange occurrence, this. As office neighbors, friends, and fellow members of the order of the culturally dislocated, we were engaging in just an ordinary part of our ongoing conversation on language, memory, cultural (non)transmission, and the many intimate losses and transformations that come as a by-product of geographic displacement. A lovely word it was, its Kirundi vowels bright, shiny, sweet to my ears. A tiny jewel wrapped …


Investigation On Utilizing Garbage As A Resource For A Sustainable Neighbourhood: Case Study Of A Neighbourhood In New Cairo, Egypt, Marianne N. Guirguis, Rania Rushdy Moussa Jan 2019

Investigation On Utilizing Garbage As A Resource For A Sustainable Neighbourhood: Case Study Of A Neighbourhood In New Cairo, Egypt, Marianne N. Guirguis, Rania Rushdy Moussa

Architectural Engineering

Waste management comprises the actions required for managing waste material produced from human activities from its source of origin to its final removal. Usually, it collects resources from all forms of matter such as gaseous, liquid, solid, and radioactive. This action is made to avoid the negative effects of wastes on the environment and human wellbeing. The effect of accumulating waste may be highly severe for numerous communities in developing countries such as Egypt. Egyptian neighbourhoods suffer from effects of accumulating local wastes and garbage. Public health and the visual image of the neighbourhoods, in addition to the different social, …


Accounting For Heterogeneous Invasion Rates Reveals Management Impacts On The Spatial Expansion Of An Invasive Species, Kim M. Pepin, David W. Wolfson, Ryan S. Miller, Michael A. Tabak, Nathan P. Snow, Kurt C. Vercauteren, Amy J. Davis Jan 2019

Accounting For Heterogeneous Invasion Rates Reveals Management Impacts On The Spatial Expansion Of An Invasive Species, Kim M. Pepin, David W. Wolfson, Ryan S. Miller, Michael A. Tabak, Nathan P. Snow, Kurt C. Vercauteren, Amy J. Davis

United States Department of Agriculture Wildlife Services: Staff Publications

Success of large-scale control programs for established invasive species is challenging to evaluate because of spatial variability in expansion rates, management techniques, and the strength of management intensity. For a well-established invasive species in the spreading phase of invasion, a useful metric of impact is the magnitude by which control slows the rate of spatial spread. The prevention of spatial spreading likely results in substantial benefits in terms of ecosystem or economic damage that is prevented by an expanding invasive species. To understand how local management actions could impact the spatial spread of an established invasive species, we analyzed distribution …


American White Pelican (Pelecanus Erythrorhynchos) Growth, Nutrition And Immunology, Treena L. Ferguson, Brian J. Rude, D. Tommy King Jan 2019

American White Pelican (Pelecanus Erythrorhynchos) Growth, Nutrition And Immunology, Treena L. Ferguson, Brian J. Rude, D. Tommy King

United States Department of Agriculture Wildlife Services: Staff Publications

Limited information about nutrition exists on American White Pelicans (Pelecanus erythrorhynchos) from hatching to fledging. To detail immunity, metabolism and nutrition of juvenile American White Pelicans, during 22-23 July 2011, 103 samples of regurgitate matter were collected at five Chase Lake, North Dakota, USA, and three Bitter Lake, South Dakota, USA, sub-colonies. Regurgitate sample nutrient content was significantly different for organic matter (P = 0.012), crude protein (P = 0.001), neutral detergent fiber (P = 0.014), acid detergent fiber (P = 0.005) and energy (P = 0.034) between North (n = 5) …


Isolation Of Rabies Virus From The Salivary Glands Of Wild And Domestic Carnivores During A Skunk Rabies Epizootic, Cornell University Jimenez, Terry R. Spraker, Jessica Anderson, Richard Bowen, Amy Gilbert Jan 2019

Isolation Of Rabies Virus From The Salivary Glands Of Wild And Domestic Carnivores During A Skunk Rabies Epizootic, Cornell University Jimenez, Terry R. Spraker, Jessica Anderson, Richard Bowen, Amy Gilbert

United States Department of Agriculture Wildlife Services: Staff Publications

Rabies is a fatal zoonotic disease of global importance. Rabies virus is shed in the saliva of infected hosts and is primarily transmitted through bite contact. Canine rabies has been eliminated from the US, but wildlife constitutes more than 90% of the reported cases of animal rabies in the US each year. In the US, several wild carnivore species are reservoirs of distinct variants of rabies virus (RV). After decades of apparent absence, the south-central skunk (SCSK) RV variant was detected in Colorado in 2007 and resulted in a large-scale epizootic in striped skunk (Mephitis mephitis) populations in northern Colorado …


Predation And Disease-Related Economic Impacts Of Wild Pigs On Livestock Producers In 13 States, Aaron M. Anderson, Chris Slootmaker, Erin Harper, Ryan S. Miller, Stephanie A. Shwiff Jan 2019

Predation And Disease-Related Economic Impacts Of Wild Pigs On Livestock Producers In 13 States, Aaron M. Anderson, Chris Slootmaker, Erin Harper, Ryan S. Miller, Stephanie A. Shwiff

United States Department of Agriculture Wildlife Services: Staff Publications

We report the results of a survey on wild pigs (Sus scrofa) damage to livestock producers in 13 US states (Alabama, Arkansas, California, Florida, Georgia, Louisiana, Mississippi, Missouri, North Carolina, Oklahoma, South Carolina, Tennessee, Texas). The survey was distributed by the USDA National Agricultural Statistical Service in the summer of 2017 to a sample of livestock producers in the 13-state region. Findings indicate that predation and disease-related damage can be substantial in certain states and for certain types of livestock. In particular, damage to cattle operations in Texas and Arkansas was substantially higher than damage in other states …


Taking The Bait: Species Taking Oral Rabies Vaccine Baits Intended For Raccoons, Betsy S. Haley, Are R. Berentsen, Richard M. Engeman Jan 2019

Taking The Bait: Species Taking Oral Rabies Vaccine Baits Intended For Raccoons, Betsy S. Haley, Are R. Berentsen, Richard M. Engeman

United States Department of Agriculture Wildlife Services: Staff Publications

Raccoon rabies in eastern USA is managed by strategically distributing oral rabies vaccine (ORV) baits. The attractiveness, palativity, density, and non-target species bait take affect ORV effectiveness. We examined raccoon and non-target species differences in investigating/removing fish-meal polymer and coated sachet baits applied to simulate two aerial bait distribution densities. Bait densities of 150 baits/km2 and 75 baits/km2 were evaluated, respectively, in zones expected to have high and low

Racc oon densities. Three primary non-target species visited baits: coyotes, white-tailed deer, and feral swine. The proportion of bait stations visited by raccoons during 1 week observation periods ranged from 50 …


In Situ Evaluation Of An Automated Aerial Bait Delivery System For Landscape-Scale Control Of Invasive Brown Treesnakes On Guam, Shane Siers, Will Pitt, John Eisemann, Larry Clark, Aaron B. Shiels, C. S. Clark, R. J. Gosnell, M. C. Messaros Jan 2019

In Situ Evaluation Of An Automated Aerial Bait Delivery System For Landscape-Scale Control Of Invasive Brown Treesnakes On Guam, Shane Siers, Will Pitt, John Eisemann, Larry Clark, Aaron B. Shiels, C. S. Clark, R. J. Gosnell, M. C. Messaros

United States Department of Agriculture Wildlife Services: Staff Publications

After decades of biodiversity loss and economic burden caused by the brown treesnake invasion on the Pacific island of Guam, relief hovers on the horizon. Previous work by USDA Wildlife Services (WS) and its National Wildlife Research Center (NWRC) demonstrated that brown treesnake numbers in forested habitats can be dramatically suppressed by aerial delivery of dead newborn mouse (DNM) baits treated with 80 mg of acetaminophen. However, manual bait preparation and application is impractical for landscape-scale treatment. WS, NWRC, and the US Department of the Interior have collaborated with Applied Design Corporation to engineer an automated bait manufacturing and delivery …


Persistence And Conspecific Observations Improve Problem-Solving Abilities Of Coyotes, Julie K. Young, Laura Touzot, Stacey P. Brummer Jan 2019

Persistence And Conspecific Observations Improve Problem-Solving Abilities Of Coyotes, Julie K. Young, Laura Touzot, Stacey P. Brummer

United States Department of Agriculture Wildlife Services: Staff Publications

Social learning has important ecological and evolutionary consequences but the role of certain factors, such as social rank, neophobia (i.e., avoidance of novel stimuli), persistence, and task-reward association, remain less understood. We examined the role of these factors in social learning by captive coyotes (Canis latrans) via three studies. Study 1 involved individual animals and eliminated object neophobia by familiarizing the subjects to the testing apparatus prior to testing. Studies 2 and 3 used mated pairs to assess social rank, and included object neophobia, but differed in that study 3 decoupled the food reward from the testing apparatus (i.e., altered …


Experimental Infections Of Norway Rats With Avian‑Derived Low‑Pathogenic Influenza A Viruses, Kaci K. Vandalen, Nicole M. Nemeth, Nicholas O. Thomas, Nicole L. Barrett, Jeremy W. Ellis, Heather J. Sullivan, Alan B. Franklin, Susan A. Shriner Jan 2019

Experimental Infections Of Norway Rats With Avian‑Derived Low‑Pathogenic Influenza A Viruses, Kaci K. Vandalen, Nicole M. Nemeth, Nicholas O. Thomas, Nicole L. Barrett, Jeremy W. Ellis, Heather J. Sullivan, Alan B. Franklin, Susan A. Shriner

United States Department of Agriculture Wildlife Services: Staff Publications

Influenza A viruses (IAVs) are a public-health, veterinary, and agricultural concern. Although wild birds are considered the primary reservoir hosts for most IAVs, wild-bird IAV strains are known to spill over into poultry, domestic or wild mammals, and humans. Occasionally, spillover events may result in adaptation or reassortment with other strains. Moreover, some IAV strains found in wild waterfowl mutate into highly pathogenic forms in poultry, causing tremendous economic losses. When domestic animals, wildlife, and humans dwell in close proximity to each other, such as may be the case with agricultural operations, wildlife may represent a potential risk for interspecies …


Movement Responses Inform Effectiveness And Consequences Of Baiting Wild Pigs For Population Control, Nathan P. Snow, Kurt C. Vercauteren Jan 2019

Movement Responses Inform Effectiveness And Consequences Of Baiting Wild Pigs For Population Control, Nathan P. Snow, Kurt C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

Wild pigs (Sus scrofa) damage agricultural and natural resources throughout their nearly global distribution. Subsequently, population control activities (e.g., trapping, shooting, or toxic baiting) frequently involve the deployment of bait to attract wild pigs. A better understanding of how wild pigs respond to bait sites can help maximize efficiency of baiting programs and identify any potential pitfalls. We examined the movement behaviors of 68 wild pigs during three stages of intensive baiting programs (i.e., 15 days each: prior, during, and post baiting) spread across two distinct study areas in southern and northern Texas, USA. We found that bait sites needed …


Raccoon (Procyon Lotor) Response To Ontario Rabies Vaccine Baits (Onrab) In St. Lawrence County, New York, Usa, Kerri Pedersen, Amy T. Gilbert, Kathleen M. Nelson, Daniel P. Morgan, Amy J. Davis, Kurt C. Vercauteren, Dennis Slate, Richard B. Chipman Jan 2019

Raccoon (Procyon Lotor) Response To Ontario Rabies Vaccine Baits (Onrab) In St. Lawrence County, New York, Usa, Kerri Pedersen, Amy T. Gilbert, Kathleen M. Nelson, Daniel P. Morgan, Amy J. Davis, Kurt C. Vercauteren, Dennis Slate, Richard B. Chipman

United States Department of Agriculture Wildlife Services: Staff Publications

Oral rabies vaccination (ORV) campaigns have been conducted annually in the US over the past two decades to prevent raccoon (Procyon lotor) rabies, which is enzootic along the eastern region of the country from southeastern Canada to Alabama. Because raccoon rabies has been eliminated from neighboring Canadian provinces, continued detection of the variant in the US is of concern due to the potential for infected raccoons to cross the border via the St. Lawrence River. Ontario Rabies Vaccine Baits (ONRAB) containing a live, recombinant human adenovirus expressing the rabies virus glycoprotein have been under experimental use in the …


Taking The Bait: Species Taking Oral Rabies Vaccine Baits Intended For Raccoons, Betsy S. Haley, Are R. Berentsen, Richard M. Engeman Jan 2019

Taking The Bait: Species Taking Oral Rabies Vaccine Baits Intended For Raccoons, Betsy S. Haley, Are R. Berentsen, Richard M. Engeman

United States Department of Agriculture Wildlife Services: Staff Publications

Raccoon rabies in eastern USA is managed by strategically distributing oral rabies vaccine (ORV) baits. The attractiveness, palativity, density, and non-target species bait take affect ORV effectiveness. We examined raccoon and non-target species differences in investigating/removing fish-meal polymer and coated sachet baits applied to simulate two aerial bait distribution densities. Bait densities of 150 baits/km2 and 75 baits/km2 were evaluated, respectively, in zones expected to have high and low raccoon densities. Three primary non-target species visited baits: coyotes, white-tailed deer, and feral swine. The proportion of bait stations visited by raccoons during 1 week observation periods ranged from …


Potential Role Of Wildlife In The Usa In The Event Of A Foot-And-Mouth Disease Virus Incursion, Vienna R. Brown, Sarah N. Bevins Jan 2019

Potential Role Of Wildlife In The Usa In The Event Of A Foot-And-Mouth Disease Virus Incursion, Vienna R. Brown, Sarah N. Bevins

United States Department of Agriculture Wildlife Services: Staff Publications

Foot-and-mouth disease (FMD) is caused by foot-and-mouth disease virus (FMDV) which affects domestic and wild cloven-hoofed species. The FMD-free status of the USA and the tremendous economic impact of a virus incursion motivated the development of this evaluation of the potential role of wildlife in the event of a virus introduction. Additionally, this manuscript contains a summary of US vulnerabilities for viral incursion and persistence which focuses specifically on the possible role of wildlife. The legal movement of susceptible live animals, animal products, by-products and animal feed containing animal products pose a risk of virus introduction and spread. Additionally, the …


Trail Cameras Are A Key Monitoring Tool For Determining Target And Non-Target Bait-Take During Rodent Removal Operations: Evidence From Desecheo Island Rat Eradication, Aaron B. Shiels, D. Will, C. Figuerola-Hernández, K.J. Swinnerton, S. Silander, C. Samra, G.W. Witmer Jan 2019

Trail Cameras Are A Key Monitoring Tool For Determining Target And Non-Target Bait-Take During Rodent Removal Operations: Evidence From Desecheo Island Rat Eradication, Aaron B. Shiels, D. Will, C. Figuerola-Hernández, K.J. Swinnerton, S. Silander, C. Samra, G.W. Witmer

United States Department of Agriculture Wildlife Services: Staff Publications

Efforts to remove invasive rodents (e.g. Rattus spp. and Mus musculus) from islands often use toxicant-laced baits containing the anticoagulants brodifacoum or diphacinone. Rodenticide baits are generally delivered through aerialor hand-broadcast, or in bait stations. These baits are not rodent-specific and are subject to non-target consumption or secondary exposure (e.g. an individual preying upon another individual that has consumed bait). During rodenticide applications, it is generally unknown which animals are visiting and consuming bait; and to quantify this, we recommend using trail cameras (e.g. Reconyxtm motion-activated infra-red) positioned to monitor individual bait pellets. To demonstrate the importance and effectiveness …


Black Bear Use Of Forest Roads In Western Washington, Gary W. Witmer Jan 2019

Black Bear Use Of Forest Roads In Western Washington, Gary W. Witmer

United States Department of Agriculture Wildlife Services: Staff Publications

Radiolocations (108) of 20 black bears were used to assess use or avoidance of 3 forest road types in western Washington. Distances of bears to each type of road were compared to distances of 108 random points using t-tests. Females and males avoided 2-lane roads, while only males avoided 1-lane roads, the most common road type in the area. Females, but not males, were located closer to overgrown, spur roads than expected. This road type has substantial cover of grasses, forbs, and berry-producing shrubs along with protective tree cover. This situation may provide easy travel for females along with security …


Home Range And Habitat Use Of West Virginia Canis Latrans (Coyote), Lauren M. Mastro, Dana J. Morin, Eric M. Gese Jan 2019

Home Range And Habitat Use Of West Virginia Canis Latrans (Coyote), Lauren M. Mastro, Dana J. Morin, Eric M. Gese

United States Department of Agriculture Wildlife Services: Staff Publications

Canis latrans (Coyote) has undergone a range expansion in the United States over the last century. As a highly opportunistic species, its home range and habitat use changes with ecological context. Coyotes were first reported in West Virginia in 1950 but were not commonly observed until the 1990s, and there is scant information on Coyotes in the region. We used telemetry data from 8 radiocollared Coyotes in West Virginia to estimate home-range size and third-order habitat selection. Home-range areas (95% utilization distributions; UDs) varied from 5.22 to 27.79 km2 (mean = 12.48 ± 2.61 km2), with highly concentrated use of …


The Role Of Scavenging In Disease Dynamics, Joaquín Vicente, Kurt C. Vercauteren Jan 2019

The Role Of Scavenging In Disease Dynamics, Joaquín Vicente, Kurt C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

Contents

Introduction................ 161

The Use of Animal Remains and the Exposure of Scavengers to Disease........ 163

The Relevance of Scavenging for Pathogens to Spread and Persist.......... 166

Human Related Factors Resulting in Increased Risk for Disease Transmission Through Scavenging.............. 170

Management of Scavenging to Reduce Disease Risks.............. 173

Restoration of Large Predators.................. 174

Elimination of Hunting of Scavengers............ 174

Destruction of Big Game and Domestic Animal Carcasses........... 174

Restoration of the Effects of Overabundance............. 175

Excluding Mammalian and Avian Scavengers from Natural Carrions.......... 176

Excluding Mammalian and Avian Scavengers from Vulture Restaurants........... 176

Conclusions and Future Perspectives........... 178

References............... 178


Using Unmanned Aerial Vehicles For Bird Harassment On Fish Ponds, Ciera A. Rhoades, Peter J. Allen, D. Tommy King Jan 2019

Using Unmanned Aerial Vehicles For Bird Harassment On Fish Ponds, Ciera A. Rhoades, Peter J. Allen, D. Tommy King

United States Department of Agriculture Wildlife Services: Staff Publications

The effects of aquaculture decline on piscivorous birds in the Mississippi Delta concern catfish farmers, with possible increases in fish loss and disease transmission. Piscivorous birds quickly habituate to most current methods of harassment (loud noises and visual disturbances) leading to increased depredation and disease. Our study was designed to test the efficacy of using unmanned aerial vehicles (UAVs) to effectively control piscivorous birds at fish farms. We hypothesized that a UAV would be more efficient at reducing the number of fish-eating birds on fish ponds than current forms of harassment. We conducted pre-treatment bird surveys, harassment observations, and post-treatment …


Locally Fixed Alleles: A Method To Localize Gene Drive To Island Populations, Jaye Sudweeks, Brandon Hollingsworth, Dimitri V. Blondel, Karl J. Campbell, Sumit Dhole, John D. Eisemann, Owain Edwards, John Godwin, Gregg R. Howald, Kevin P. Oh, Antoinette J. Piaggio, Thomas A.A. Prowse, Joshua V. Ross, J. Royden Saah, Aaron B. Shiels, Paul Q. Thomas, David W. Threadgill, Michael R. Vella, Fred Gould, Alun L. Lloyd Jan 2019

Locally Fixed Alleles: A Method To Localize Gene Drive To Island Populations, Jaye Sudweeks, Brandon Hollingsworth, Dimitri V. Blondel, Karl J. Campbell, Sumit Dhole, John D. Eisemann, Owain Edwards, John Godwin, Gregg R. Howald, Kevin P. Oh, Antoinette J. Piaggio, Thomas A.A. Prowse, Joshua V. Ross, J. Royden Saah, Aaron B. Shiels, Paul Q. Thomas, David W. Threadgill, Michael R. Vella, Fred Gould, Alun L. Lloyd

United States Department of Agriculture Wildlife Services: Staff Publications

Invasive species pose a major threat to biodiversity on islands. While successes have been achieved using traditional removal methods, such as toxicants aimed at rodents, these approaches have limitations and various off-target effects on island ecosystems. Gene drive technologies designed to eliminate a population provide an alternative approach, but the potential for drive-bearing individuals to escape from the target release area and impact populations elsewhere is a major concern. Here we propose the “Locally Fixed Alleles” approach as a novel means for localizing elimination by a drive to an island population that exhibits significant genetic isolation from neighboring populations. Our …


3,190,000 Barrels: The Deepwater Horizon Oil Spill, Jessica Young, Special Collections, Fleet Library Jan 2019

3,190,000 Barrels: The Deepwater Horizon Oil Spill, Jessica Young, Special Collections, Fleet Library

6th Baker & Whitehill Student Artists' Book Contest 2020

No abstract provided.


Nmr Metabolomics Protocols For Drug Discovery, Fatema Bhinderwala, Robert Powers Jan 2019

Nmr Metabolomics Protocols For Drug Discovery, Fatema Bhinderwala, Robert Powers

Department of Chemistry: Faculty Publications

Drug discovery is an extremely difficult and challenging endeavor with a very high failure rate. The task of identifying a drug that is safe, selective and effective is a daunting proposition because disease biology is complex and highly variable across patients. Metabolomics enables the discovery of disease biomarkers, which provides insights into the molecular and metabolic basis of disease and may be used to assess treatment prognosis and outcome. In this regard, metabolomics has evolved to become an important component of the drug discovery process to resolve efficacy and toxicity issues, and as a tool for precision medicine. A detailed …


Influenza H1 Mosaic Hemagglutinin Vaccine Induces Broad Immunity And Protection In Mice, Brigette N. Corder, Brianna L. Bullard, Jennifer L. Debeauchamp, Natalia A. Ilyushina, Richard J. Webby, Eric A. Weaver Jan 2019

Influenza H1 Mosaic Hemagglutinin Vaccine Induces Broad Immunity And Protection In Mice, Brigette N. Corder, Brianna L. Bullard, Jennifer L. Debeauchamp, Natalia A. Ilyushina, Richard J. Webby, Eric A. Weaver

School of Biological Sciences: Faculty Publications

Annually, influenza A virus (IAV) infects ~5–10% of adults and 20–30% of children worldwide. The primary resource to protect against infection is by vaccination. However, vaccination only induces strain-specific and transient immunity. Vaccine strategies that induce cross-protective immunity against the broad diversity of IAV are needed. Here we developed and tested a novel mosaic H1 HA immunogen. The mosaic immunogen was optimized in silico to include the most potential B and T cell epitopes (PBTE) across a diverse population of human H1 IAV. Phylogenetic analysis showed that the mosaic HA localizes towards the non-pandemic 2009 strains which encompasses the broadest …


Life Ascending: Mechanism And Process In Physiological Adaptation To High-Altitude Hypoxia, Jay F. Storz, Graham R. Scott Jan 2019

Life Ascending: Mechanism And Process In Physiological Adaptation To High-Altitude Hypoxia, Jay F. Storz, Graham R. Scott

School of Biological Sciences: Faculty Publications

To cope with the reduced availability of O2 at high altitude, air-breathing vertebrates have evolved myriad adjustments in the cardiorespiratory system to match tissue O2 delivery with metabolic O2 demand. We explain how changes at interacting steps of the O2 transport pathway contribute to plastic and evolved changes in whole-animal aerobic performance under hypoxia. In vertebrates native to high altitude, enhancements of aerobic performance under hypoxia are attributable to a combination of environ- mentally induced and evolved changes in multiple steps of the pathway. Additionally, evidence suggests that many high-altitude natives have evolved mechanisms for attenuating maladaptive acclimatization responses to …


Ecological Pleiotropy And Indirect Effects Alter The Potential For Evolutionary Rescue, John P. Delong, Jonathan Belmaker Jan 2019

Ecological Pleiotropy And Indirect Effects Alter The Potential For Evolutionary Rescue, John P. Delong, Jonathan Belmaker

School of Biological Sciences: Faculty Publications

Invading predators can negatively affect naïve prey populations due to a lack of evolved defenses. Many species therefore may be at risk of extinction due to overexploitation by exotic predators. Yet the strong selective effect of predation might drive evolution of imperiled prey toward more resistant forms, potentially allowing the prey to persist. We evaluated the potential for evolutionary rescue in an imperiled prey using Gillespie eco‐evolutionary models (GEMs). We focused on a system parameterized for protists where changes in prey body size may influence intrinsic rate of population growth, space clearance rate (initial slope of the functional response), and …